Abstract: Isomaltulose (6-0-alpha-D-glucopyranosido-D-fructose) is produced by passing a pure sucrose solution through a reactor containing dead, immobilized cells of an isomaltulose-forming microorganism. The sucrose solution preferably contains 45 to 75% by weight sucrose and has a temperature of 45.degree. to 65.degree. C.
Abstract: Powdery crystalline maltose characterized by a high concentration of the beta-anomer of maltose monohydrate is produced by:(1) obtaining a high purity maltose solution containing not less than 90% maltose and not more than 2.5% maltotriose by enzymatic saccharification of a liquefied starch solution having a low degree of hydrolysis;(2) concentrating the high purity maltose solution to a solid content of 65 to 80%;(3) adding seed crystals of beta-maltose monohydrate;(4) precipitating maltose monohydrate crystals in a primary crystallization stage;(5) spray drying the resulting massecuite to obtain a powdery product with a water content of 5.5-7.5%; and(6) aging the powdery product at a temperature of 50.degree.-75.degree. C., relative humidity of 50-70% and absolute humidity of 45-185 g water/Kg dry air.A product having low hygroscopicity is produced by this method.
Abstract: An antibiotic complex, consisting of two major components, has been isolated from fermentations of a new subspecies of Streptomyces albus culture. The two major components from the complex are two new macrolide antibiotics, which are active as antibacterial agents against certain gram-positive and gram-negative microorganisms.
Type:
Grant
Filed:
May 3, 1982
Date of Patent:
October 25, 1983
Assignee:
Pfizer Inc.
Inventors:
Walter D. Celmer, Walter P. Cullen, Riichiro Shibakawa, Junsuke Tone
Abstract: Sucrose mutase in whole cells of Protaminobacter rubrum #l is immobilized by contacting the cells with tannic acid, polyethylenimine, and an adduct of glutaraldehyde and an epihalohydrin/polyamine copolymer. The resultant reaction product has improved sucrose mutase activity and physical characteristics for use in a packed-bed reactor to convert sucrose to palatinose.
Abstract: Palatinose is produced from sucrose with an immobilized bacteria containing alpha-glucosyl transferase. The bacteria is immobilized by entrapping cells of the bacteria in calcium alginate gel granules and treating the granules with polyethyleneimine and glutaraldehyde. Palatinose is efficiently produced by packing the bacteria-containing granules in a column and passing a sucrose solution through the column at high velocity.
Abstract: Isomaltulose is produced by a process in which at least the isomaltulose-forming enzyme system of an isomaltulose-forming micro-organism genus Erwinia is immobilized on calcium alginate gel and then the immobilized enzyme system is contacted with a sucrose solution to convert at least part of the sucrose to isomaltulose.
Type:
Grant
Filed:
October 28, 1980
Date of Patent:
November 16, 1982
Assignee:
Talres Development (N.A.) N.V.
Inventors:
Christopher Bucke, Peter S. J. Cheetham
Abstract: Novel antibiotic 3-trehalosamine (U-59,834) producible in a fermentation under controlled conditions using the new microorganism Nocardiopsis trehalosei sp. nov., NRRL 12026.This antibiotic is active against Gram-positive bacteria, for example, Staphylococcus aureus, Bacillus subtilis, and Diplococcus pneumoniae. Thus, 3-trehalosamine can be used in various environments to eradicate or control such bacteria.
Type:
Grant
Filed:
September 17, 1979
Date of Patent:
June 30, 1981
Assignee:
The Upjohn Company
Inventors:
Lester A. Dolak, Alice L. Laborde, Thomas M. Castle
Abstract: Malt having a high content of alpha-1,6-hydrolase activity is prepared by germinating previously steeped barely until the average acrospire reaches a length of at least 11/4 times the average length of the kernals and it contains at least 55 units of alpha-1,6-hydrolase activity per gram of malt. The malt provides more complete hydrolyzing of starch to glucose and maltose, and it is useful in producing low carbohydrate beer, in producing distilled alcoholic beverages and in producing maltose syrup.
Type:
Grant
Filed:
July 28, 1978
Date of Patent:
February 17, 1981
Assignee:
Kurth Malting Corporation
Inventors:
George W. Pratt, Thomas W. Chapple, Michael J. Fahy
Abstract: The antibiotics Papulacandin A and Papulacandin B are etherified at the phenolic groups in positions 10 and/or 12 by introducing a group--CH.sub.2 --Kwherein K is a hydrocarbon radical which is either unsaturated and aliphatic, or it is saturated or unsaturated and substituted by cyclic hydrocarbons, such as aromatic or heterocyclic ones, or by functional groups, such as halogens, carboxyl groups, carboxyl ester or amide groups. These ethers are characterized by a good antifungal action e.g. against Candida albicans and also by an antifiral action.