Preparing Compound Containing Saccharide Radical Patents (Class 435/72)
  • Patent number: 10329588
    Abstract: The invention relates to means and methods for the biomethanation of H2 and CO2. In particular, the invention relates to devices for producing methane by means of methanogenic microorganisms by converting H2 and CO2, wherein the devices comprise at least one reactor, an aqueous medium, which is provided in the at least one reactor, wherein the methanogenic microorganisms are contained in the aqueous medium, a feeding apparatus, which is designed to introduce H2 and CO2 into the at least one reactor, wherein H2 and CO2 form a gaseous mixture therein, and a reaction-increasing device, which is designed to enlarge the contact surface between the aqueous medium having the methanogenic microorganisms and the gaseous mixture. The invention further relates to methods for producing methane in a reactor device by means of methanogenic microorganisms.
    Type: Grant
    Filed: June 27, 2014
    Date of Patent: June 25, 2019
    Inventor: Matthias Brunner
  • Patent number: 10301226
    Abstract: A process for production of anaerobic digestate based organic fertilizer includes combining anaerobic digestate and one or more grain by-products to create a combination of anaerobic digestate and one or more grain by-products. The combination of anaerobic digestate and one or more grain by-products is processed to yield the pH adjusted anaerobic digestate based organic fertilizer product.
    Type: Grant
    Filed: April 13, 2016
    Date of Patent: May 28, 2019
    Assignee: True Organic Products, Inc.
    Inventor: Jacob Matthew Evans
  • Patent number: 10165787
    Abstract: A GH10 xylanase variant is disclosed herein. This GH10 xylanase variant has increased thermostability compared with a parent GH10 xylanase enzyme comprising at least 90% sequence identity with the amino acid sequence of SEQ ID No. 1 wherein the variant has been modified at two or more of the following positions 7, 33, 79, 217 and 298 corresponding to the amino acid numbering of SEQ ID No. 1.
    Type: Grant
    Filed: January 30, 2015
    Date of Patent: January 1, 2019
    Assignee: DUPONT NUTRITION BIOSCIENCES APS
    Inventors: Rikke Hoeegh Lorentsen, Susan Arent Lund, Igor Nikolaev, Jan Hendrik A. Van Tuijl, Bert Koops
  • Patent number: 10144939
    Abstract: The invention relates to a process for the preparation of a fermentation product from lignocellulosic material, comprising the following steps: a) optionally, pre-treatment of the lignocellulosic material, b) optionally, washing of the optionally pretreated lignocellulosic material, c) enzymatic hydrolysis of the optionally washed and/or optionally pretreated lignocellulosic material using an enzyme composition comprising at least two cellulases and whereby the enzyme composition at least comprises LPMO, and optionally purifying the hydrolyzed lignocellulosic material, d) fermentation of the hydrolyzed lignocellulosic material to produce a fermentation product, and e) optionally, recovery of a fermentation product, wherein oxygen is consumed in amounts corresponding to between 20 and 5000 mmol molecular oxygen per kg glucan present in the lignocellulosic material, the oxygen is added after the pretreatment and before and/or during the enzymatic hydrolysis of the lignocellulosic material, preferably in an a
    Type: Grant
    Filed: April 29, 2015
    Date of Patent: December 4, 2018
    Assignee: DSM IP ASSETS B.V.
    Inventors: Bertus Noordam, Michael Petrus Jozef Berkhout
  • Patent number: 10112868
    Abstract: A method for post-consumer waste segregation, comminution, and creation of a cementitious aggregate, that enables more complete reclamation of zorba from a processing stream segregable from plastic waste. The plastic waste is simultaneously impregnated with silica to create a cementitious aggregate employable with load bearing utility as a substitute for traditional concrete aggregates.
    Type: Grant
    Filed: February 27, 2017
    Date of Patent: October 30, 2018
    Inventors: Kevin Furnary, Earl T. Balkum
  • Patent number: 9963692
    Abstract: The thermostable cellobiohydrolase of the present invention is a polypeptide which has cellobiohydrolase activity at least under conditions of a temperature of 75° C. and a pH of 5.5, and which includes a polypeptide including an amino acid sequence represented by SEQ ID NO: 1, 3, 5, or 7, a polypeptide including an amino acid sequence in which one or several amino acids are deleted, substituted, or added in an amino acid sequence represented by SEQ ID NO: 1, 3, 5, or 7, or a polypeptide including an amino acid sequence having 80% or greater but less than 100% sequence identity with an amino acid sequence represented by SEQ ID NO: 1, 3, 5, or 7.
    Type: Grant
    Filed: March 27, 2014
    Date of Patent: May 8, 2018
    Assignees: Honda Motor Co., Ltd., Kazusa DNA Research Institute
    Inventors: Migiwa Suda, Jiro Ohkuma, Asuka Yamaguchi, Yoshitsugu Hirose, Yasuhiro Kondo, Tomohiko Kato, Daisuke Shibata
  • Patent number: 9963727
    Abstract: The processes disclosed herein include saccharifying cellulosic and/or lignocellulosic biomass and fermenting the sugars to produce a sugar alcohol.
    Type: Grant
    Filed: September 3, 2013
    Date of Patent: May 8, 2018
    Assignee: XYLECO, INC.
    Inventors: Marshall Medoff, Thomas Craig Masterman, Jaewoong Moon, Aiichiro Yoshida
  • Patent number: 9963725
    Abstract: The present invention provides a continuous and cost effective chemo-enzymatic process for fractionation of holocellulose, obtained from agri-waste, into arabinoxylooligosaccharides, xylooligosaccharides and cellooligosaccharides, suitable for commercial applications. The process comprises of mixing the holocellulose with an aqueous medium in a controlled condition to obtain an aqueous extract comprising of soluble arabinoxylooligosaccharides and insoluble solid fraction; followed by treatment of the solid fraction with an aqueous alkali solution at controlled condition to obtain soluble xylooligosaccharides and cellulose residue. The cellulose residue is thereafter suspended in aqueous acid solution followed by treatment with an enzyme at controlled condition to obtain soluble cellooligosaccharides. The arabinoxylooligosaccharides, xylooligosaccharides and cellooligosaccharides obtained from the process have a degree of polymerization greater than 4.
    Type: Grant
    Filed: January 16, 2015
    Date of Patent: May 8, 2018
    Assignee: Arvind Mallinath Lali
    Inventor: Arvind Mallinath Lali
  • Patent number: 9957528
    Abstract: The invention relates to a process for the preparation of a sugar product from ligno-cellulosic material, comprising the following steps: a) optionally pre-treatment of the ligno-cellulosic material; b) optionally washing of the optionally pre-treated ligno-cellulosic material; c) enzymatic hydrolysis of the optionally washed and/or optionally pre-treated ligno-cellulosic material using an enzyme composition comprising at least two cellulase and whereby the enzyme composition at least comprises GH61; and d) optionally recovery of a sugar product; wherein during part of the time of the enzymatic hydrolysis, oxygen is added to the ligno-cellulosic material and during part of the time of the enzymatic hydrolysis less oxygen is added to the ligno-cellulosic material compared to the other part of the time of the enzymatic hydrolysis, preferably no oxygen is added to the ligno-cellulosic material.
    Type: Grant
    Filed: November 7, 2013
    Date of Patent: May 1, 2018
    Assignee: DSM IP ASSETS B.V.
    Inventors: Bertus Noordam, Michael Petrus Jozef Berkhout, Aida Hiseni
  • Patent number: 9758643
    Abstract: Methods for the production of a biodegradable plastics material obtained from plant waste materials are provided which include the steps of dissolving plant waste material in an anhydrous solvent which includes anhydrous trifluoroacetic acid in order to dissolve a cellulose fraction of the material, the waste material being at least partly dehydrated in such a way that its water content is not likely to cause hydrolysis of the cellulose fraction, and removing the solvent from the solution containing the non-hydrolyzed cellulose fraction.
    Type: Grant
    Filed: October 29, 2014
    Date of Patent: September 12, 2017
    Assignee: FONDAZIONE ISTITUTO ITALIANO DI TENOLOGIA
    Inventors: Ilker S. Bayer, Elisa Mele, Despina Fragouli, Roberto Cingolani, Athanasia Athanasiou
  • Patent number: 9637725
    Abstract: Provided are isolated polypeptides having catalase activity and polynucleotides encoding the polypeptides. Also provided are nucleic acid constructs, vectors and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides.
    Type: Grant
    Filed: December 19, 2012
    Date of Patent: May 2, 2017
    Assignee: Novozymes Inc.
    Inventors: Ye Liu, Junxin Duan, Yu Zhang, Lan Tang
  • Patent number: 9593388
    Abstract: A selective removal of metal and its anion species that are detrimental to subsequent hydrothermal hydrocatalytic conversion from the biomass feed prior to carrying out catalytic hydrogenation/hydrogenolysis/hydrodeoxygenation of the biomass in a manner that does not reduce the effectiveness of the hydrothermal hydrocatalytic treatment while minimizing the amount of water used in the process is provided.
    Type: Grant
    Filed: December 18, 2014
    Date of Patent: March 14, 2017
    Assignee: SHELL OIL COMPANY
    Inventors: Joseph Broun Powell, Juben Nemchand Chheda
  • Patent number: 9593448
    Abstract: A selective removal of chlorine and phosphorus that are detrimental to subsequent hydrothermal hydrocatalytic conversion from the biomass feed prior to carrying out catalytic hydrogenation/hydrogenolysis/hydrodeoxygenation of the biomass in a manner that does not reduce the effectiveness of the hydrothermal hydrocatalytic treatment while minimizing the amount of water used in the process is provided.
    Type: Grant
    Filed: December 18, 2014
    Date of Patent: March 14, 2017
    Assignee: SHELL OIL COMPANY
    Inventors: Joseph Broun Powell, Juben Nemchand Chheda
  • Patent number: 9562247
    Abstract: An object of the present invention is to provide a method for industrially producing a branched glucan having a cyclic structure. The method for producing a branched glucan having a cyclic structure comprises the steps of: (1) preparing a mixed liquid which contains a branching enzyme in which starch granules are suspended at a concentration of 5% by weight or more and 50% by weight or less, and allowing the branching enzyme to act on starch in the starch granules, wherein a temperature of the mixed liquid at the time of preparation is 0° C. or higher and not higher than the gelatinization starting temperature of the starch granule; and (2) elevating the temperature of the mixed liquid to 85° C. or higher and 129° C. or lower, wherein in the method, none of ?-amylase, ?-amylase, amyloglucosidase and ?transglucosidase is added to the mixed liquid.
    Type: Grant
    Filed: December 2, 2011
    Date of Patent: February 7, 2017
    Assignee: Ezaki Glico Co., Ltd.
    Inventors: Takeshi Takaha, Kouji Odan, Michiyo Yanase, Iwao Kojima, Tsunehisa Akiyama
  • Patent number: 9562177
    Abstract: A highly homogeneous starch-based glue composition is obtained by enzymatic modification of the starch with a branching enzyme which is supplied in an enzymatically modified starch with high long-term stability. The starch has a viscosity stability index SI of less than or equal to 1.3, calculated by the quotient of viscosity after 14 days and by viscosity after 2 hours after preparation of the starch. The starch is suitable for liquid storage, which is stable in the long-term, of a ready-to-use paste with a high bonding strength.
    Type: Grant
    Filed: November 15, 2011
    Date of Patent: February 7, 2017
    Assignee: Agrana Staerke GmbH
    Inventors: Karl-Jürgen Mann, Martin Kozich, Dietmar Grüll, Marnik Michel Wastyn
  • Patent number: 9512433
    Abstract: The present invention relates to a cell to be stably cultured in a medium, which cell is adjusted for the production of oligosaccharides, the cell being transformed to comprise at least one nucleic acid sequence coding for an enzyme involved in oligosaccharide synthesis. In addition the cell is transformed to comprise at least one nucleic acid sequence coding for a protein of the sugar efflux transporter family, a functional homolog or derivative thereof. Further, the invention concerns a method for the production of oligosaccharides involving above cell.
    Type: Grant
    Filed: December 9, 2013
    Date of Patent: December 6, 2016
    Assignee: JENNEWEIN BIOTECHNOLOGIE GmbH
    Inventors: Stefan Jennewein, Eric Huefner, Julia Parkot
  • Patent number: 9506048
    Abstract: The present invention relates to isolated polypeptides having cellobiohydrolase activity, catalytic domains, and cellulose binding domains and polynucleotides encoding the polypeptides, catalytic domains, and cellulose binding domains. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides, catalytic domains, or cellulose binding domains.
    Type: Grant
    Filed: January 26, 2012
    Date of Patent: November 29, 2016
    Assignees: Novozymes, Inc., Novozymes A/S
    Inventors: Mary Ann Stringer, Brett McBrayer
  • Patent number: 9487549
    Abstract: A method for the preparation of lignin from lignocellulosic material by pulping with alcohol, in particular with a C1-4 alcohol, water and a base, in particular NaOH, at a temperature below 100° C., in particular from 40° C. to 90° C., in particular from 50° C. to 70° C., characterized in that 3 to 12 parts of base, in particular 4 to 10 parts of base, in particular preferable 5 to 8 parts of base, are used per 100 parts of the dry lignocellulosic material to be pulped.
    Type: Grant
    Filed: September 1, 2011
    Date of Patent: November 8, 2016
    Assignee: Annikki GmbH
    Inventors: Karin Fackler, Thomas Ters, Ortwin Ertl, Kurt Messner
  • Patent number: 9458443
    Abstract: The invention discloses cellulase enzymes with optimized properties for processing of cellulose- and lignocellulose-containing substrates. In particular, cellobiohydrolase enzymes with preferred characteristics are disclosed. The present invention provides fusion, insertion, deletion and/or substitution variants of such enzymes. Enzyme variants have enhanced thermostability, proteolytic stability, specific activity and/or stability at extreme pH. Nucleic acid molecules encoding said enzymes, a composition comprising said enzymes, a method for preparation, and the use for cellulose processing and/or for the production of biofuels are disclosed.
    Type: Grant
    Filed: February 11, 2011
    Date of Patent: October 4, 2016
    Assignee: SUD-CHEMIE IP GMBH & CO. KG
    Inventors: Ulrich Kettling, Christoph Reisinger, Thomas Brück, Andre Koltermann, Jochen Gerlach, Isabel Unterstrasser, Lutz Röcher, Markus Rarbach, Jörg Claren, Andreas Kohl, Jan Carsten Pieck, Dominik Schlosser
  • Patent number: 9458482
    Abstract: A method is provided in which pretreated and densified cellulosic biomass particulates can be hydrolyzed at a high solids loading rate as compared with the solids loading rate of loose hydrolysable cellulosic biomass fibers. The resulting high concentration sugar-containing stream can be easily converted to biofuels or to an entire suite of other useful bioproducts.
    Type: Grant
    Filed: December 22, 2014
    Date of Patent: October 4, 2016
    Assignees: THE MICHIGAN BIOTECHNOLOGY INSTITUTE, BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY
    Inventors: Bryan Bals, Farzaneh Teymouri, Timothy J. Campbell, Bruce E. Dale
  • Patent number: 9404137
    Abstract: The present invention relates to compositions comprising: a polypeptide having cellulolytic enhancing activity and a heterocyclic compound. The present invention also relates to methods of using the compositions.
    Type: Grant
    Filed: August 5, 2011
    Date of Patent: August 2, 2016
    Assignee: NOVOZYMES, INC.
    Inventors: Feng Xu, Matthew Sweeney, Jason Quinlan
  • Patent number: 9376504
    Abstract: This disclosure describes techniques for using a single feedstock of barley to produce a fermented product and a method for filtering a large-particles stream from a liquid stream containing small particles of a process stream using a series of mechanical separation devices to increase yield.
    Type: Grant
    Filed: September 16, 2013
    Date of Patent: June 28, 2016
    Assignee: ICM, Inc.
    Inventors: Kurt A. Dieker, Charles C. Gallop, Scott D. Kohl, Keith Tjaden, Justin McMillen
  • Patent number: 9376461
    Abstract: Provided herein is a simple, one-step, non-enzymatic synthesis of O-Acetyl-ADP-ribose (OAADPR) from NAD and sodium acetate in acetic acid. The extension of this reaction to other carboxylic acids, demonstrates that the reaction between NAD, and NAD analogs produces mixtures of the corresponding 2?- and 3?-carboxylic esters. Included are O-carboxyl-ADP-ribose compounds and corresponding methods of synthesis (e.g., O-propionyl-ADP-ribose, O-succinyl-ADP-ribose, O-malonyl-ADP-ribose), as well as non-adenosine nucleoside compounds.
    Type: Grant
    Filed: June 6, 2012
    Date of Patent: June 28, 2016
    Assignee: GlaxoSmithKline LLC
    Inventors: Karsten Koppetsch, Bruce G. Szczepankiewicz, Robert B Perni
  • Patent number: 9322007
    Abstract: The disclosure provides variant Cel6a enzymes having increased thermostability, methods of making and using such polypeptides.
    Type: Grant
    Filed: July 20, 2012
    Date of Patent: April 26, 2016
    Assignee: The California Institute of Technology
    Inventors: Frances H. Arnold, Indira Wu
  • Patent number: 9255284
    Abstract: Methods to digest carbohydrates, especially lignocelluloses and hemicelluloses, using fungal proteins previously not recognized as having this activity are described.
    Type: Grant
    Filed: April 15, 2014
    Date of Patent: February 9, 2016
    Assignee: NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWETENSCHAPPELIJK ONDERZOEK TNO
    Inventor: Peter Jan Punt
  • Patent number: 9206406
    Abstract: Provided is a modified Family 1 carbohydrate binding module (CBM) comprising amino acid substitutions at one or more of positions 10, 11, 12, 14, 17, 21, 24, 29, 31, 33, and 37, said position determined from alignment of a Family 1 CBM amino acid sequence with SEQ ID NO: 30, and exhibiting from about 50% to about 99.9% amino acid sequence identity to SEQ ID NO: 30. Also provided are modified glycosidase enzymes comprising the modified Family 1 CBM, genetic constructs and genetically modified microbes for expressing the modified Family 1 CBM or modified glycosidase enzyme. The modified Family 1 CBM confers reduced lignin binding and/or increased hydrolyzing activity in the presence of lignin to the modified glycosidase enzyme, which may be used in a process for hydrolyzing cellulose or hemicellulose in the presence of lignin.
    Type: Grant
    Filed: February 11, 2011
    Date of Patent: December 8, 2015
    Assignee: IOGEN ENERGY CORPORATION
    Inventors: John J. Tomashek, Brian R. Scott, Daniel Kolczynski
  • Patent number: 9139858
    Abstract: A method to treat a lignocellulosic material including: pretreating the lignocellulosic material to produce a slurry; adding an alkali material to the slurry in a first conveyor; adding a first portion of an enzyme solution to the slurry while the slurry is in, entering or passing through the discharge of a second conveyor; transferring the slurry with the enzyme solution from the second conveyor slurry to a mixer; mixing the slurry with a second portion of the enzyme solution, and transferring the slurry with the enzyme solution mixed with the first and second portions of the enzyme solution to a first reactor vessel for enzymatic hydrolysis, wherein the viscosity of the slurry is reduced in the first reactor vessel.
    Type: Grant
    Filed: December 10, 2013
    Date of Patent: September 22, 2015
    Assignee: Andritz Inc.
    Inventors: Rodolfo Romero, Bertil Stromberg
  • Patent number: 9109049
    Abstract: The present invention relates to a method for pretreating lignocellulosic biomass containing alkali and/or alkaline earth metal (AAEM). The method comprises providing a lignocellulosic biomass containing AAEM; determining the amount of the AAEM present in the lignocellulosic biomass; identifying, based on said determining, the amount of a mineral acid sufficient to completely convert the AAEM in the lignocellulosic biomass to thermally-stable, catalytically-inert salts; and treating the lignocellulosic biomass with the identified amount of the mineral acid, wherein the treated lignocellulosic biomass contains thermally-stable, catalytically inert AAEM salts.
    Type: Grant
    Filed: March 14, 2013
    Date of Patent: August 18, 2015
    Assignee: Iowa State University Research Foundation, Inc.
    Inventors: Najeeb M. Kuzhiyil, Robert C. Brown, Dustin Lee Dalluge
  • Patent number: 9080187
    Abstract: Described herein are methods, compositions and synthetic biology approaches for solvent production, including but not limited to butanol production. Described herein are recombinant bacteria and yeast strains which may be used in production of a solvent, including but not limited to butanol, from lignocellulosic and other plant-based feedstocks. Described herein are methods of producing solvents, including but not limited to butanol, using bacteria and yeast strains. Described herein are methods of producing organisms that display highly efficient butanol production.
    Type: Grant
    Filed: May 19, 2008
    Date of Patent: July 14, 2015
    Assignees: The Board of Trustees of the University of Illinois, Eastman Renewable Materials, LLC
    Inventors: Hans P. Blaschek, Steven F. Stoddard, Zhen Shi
  • Publication number: 20150147783
    Abstract: The present invention relates to an isolated mutant eubacterium comprising at least one mutation resulting in a substitution of at least one amino acid in the beta-subunit of the RNA-polymerase encoded for by the rpoB-gene providing an altered production of a product of interest when said production of a product of interest is compared to the production of the same product in an isogenic wild type strain grown at identical conditions, wherein the substitution of at least one amino acid occurs at any of positions 469, 478, 482, 485, or 487 of SEQ ID NO:2, or at the equivalent positions in any eubacterial RNA-polymerase beta-subunit family member. Another aspect of the invention relates to a process for producing at least one product of interest in a mutant eubacterium and to a use of the mutant eubacterium according to the invention for producing at least one product of interest.
    Type: Application
    Filed: February 9, 2015
    Publication date: May 28, 2015
    Inventors: Steen Troels Joergensen, Jens Toenne Andersen, Niels Banke, Preben Nielsen
  • Publication number: 20150139958
    Abstract: Provided are a feed composition, which can be stored for a long time and is easily produced and adjustable in components, and which can increase the body weight and reduce a feed conversion ratio of farm animals to which the feed composition is fed, and a production method for the feed composition. In the feed composition, a liquid feed additive obtained by fermenting a carbohydrate-containing carbohydrate raw material by Aspergillus is substituted for 5 to 50% on a dry matter basis of a feed raw-material.
    Type: Application
    Filed: July 16, 2013
    Publication date: May 21, 2015
    Inventor: Masahiro Yamamoto
  • Patent number: 9023628
    Abstract: Biomass (e.g., plant biomass, animal biomass, and municipal waste biomass) is processed to produce useful products, such as fuels. For example, systems are described that can use feedstock materials, such as cellulosic and/or lignocellulosic materials, to produce ethanol and/or butanol, e.g., by fermentation.
    Type: Grant
    Filed: September 11, 2014
    Date of Patent: May 5, 2015
    Assignee: Xyleco, Inc.
    Inventor: Marshall Medoff
  • Patent number: 9005946
    Abstract: The invention provides variants of the Clostridium thermocellum endoglucanase (CelG) that have improved endoglucanase activity compared to the wild type enzyme. Also provided are related polynucleotides, compositions, vectors, host cells, and methods of use.
    Type: Grant
    Filed: March 10, 2010
    Date of Patent: April 14, 2015
    Assignee: Codexis, Inc.
    Inventors: Jie Yang, Xiyun Zhang, Ish Kumar Dhawan, Andrew Shaw
  • Patent number: 8999692
    Abstract: The present disclosure relates to cellulase variants. In particular the present disclosure relates to cellulase variants having reduced binding to non-cellulosic materials. Also described are nucleic acids encoding the cellulase, compositions comprising said cellulase, methods of identifying cellulose variants and methods of using the compositions.
    Type: Grant
    Filed: July 6, 2012
    Date of Patent: April 7, 2015
    Assignee: Danisco US Inc.
    Inventors: Luis G. Cascao-Pereira, Thijs Kaper, Bradley R. Kelemen, Amy D. Liu
  • Patent number: 8999705
    Abstract: This invention provides nucleic acids and proteins involved in oligosaccharide modification in the species Bifidobacteria. The invention provides methods for utilizing the proteins of the invention to generate human milk oligosaccharides or oligosaccharide mimics. The invention also provides compositions containing the human milk oligosaccharides or oligosaccharide mimics and methods for use.
    Type: Grant
    Filed: December 19, 2012
    Date of Patent: April 7, 2015
    Assignee: The Regents of the University of California
    Inventors: David A. Mills, Carlito B. Lebrilla, J. Bruce German, David Sela
  • Publication number: 20150093785
    Abstract: The invention provides apparatus and processes for cultivating algae.
    Type: Application
    Filed: December 8, 2014
    Publication date: April 2, 2015
    Inventors: Ari KETOLA, Veikko LATVALA
  • Patent number: 8980578
    Abstract: The present invention provides fungal xylanase and/or beta-xylosidase enzymes suitable for use in saccharification reactions. The present application further provides genetically modified fungal organisms that produce xylanase and/or beta-xylosidases, as well as enzyme mixtures exhibiting enhanced hydrolysis of cellulosic material to fermentable sugars, enzyme mixtures produced by the genetically modified fungal organisms, and methods for producing fermentable sugars from cellulose using such enzyme mixtures.
    Type: Grant
    Filed: June 10, 2013
    Date of Patent: March 17, 2015
    Assignee: Codexis, Inc.
    Inventors: Ryan Fong, Xiyun Zhang, Chris Noriega, Nicholas Agard, Anupam Gohel, Derek Smith
  • Patent number: 8969074
    Abstract: The present invention relates to an electromagnetic bioaccelerator for obtaining biomass by simulating environmental marine conditions, comprising at least the following elements: octagonal biomass converters (1), seawater reserve tanks (3), particle filters (4), UV light filters (5), feedback and mixture tanks (6), pressurization feed tanks (8), manometers (9), pressure controllers (10), buffer tanks (11), expansion tanks with a safety valve (12), heat exchangers (13), temperature control thermostats (14), recycled water feedback tanks (15), reinjection pumps (16), centrifuges for separating the biomass from the water (17), desuperheaters (18); control panels (25), recirculation pumps (26), densimeters (27), biomass mechanical extraction systems by means of centrifugation (32) and biomass accumulation tanks (33).
    Type: Grant
    Filed: December 14, 2007
    Date of Patent: March 3, 2015
    Assignee: Bio Fuel Systems, S.L.
    Inventors: Bernard A. J. Stroïazzo-Mougin, Cristian Gomis Catala
  • Patent number: 8945352
    Abstract: Methods are provided for changing a molecular structure of a biomass feedstock. The methods include a screw extrusion process.
    Type: Grant
    Filed: May 2, 2011
    Date of Patent: February 3, 2015
    Assignee: Xyleco, Inc.
    Inventor: Marshall Medoff
  • Patent number: 8945245
    Abstract: A method is provided in which pretreated and densified cellulosic biomass particulates can be hydrolyzed at a high solids loading rate as compared with the solids loading rate of loose hydrolysable cellulosic biomass fibers. The resulting high concentration sugar-containing stream can be easily converted to biofuels or an entire suite of other useful bioproducts.
    Type: Grant
    Filed: April 27, 2012
    Date of Patent: February 3, 2015
    Assignees: The Michigan Biotechnology Institute, Board of Trustees of Michigan State University
    Inventors: Bryan Bals, Farzaneh Teymouri, Tim Campbell, Bruce Dale
  • Publication number: 20150031084
    Abstract: Methods and systems for producing a biofuel using genetically modified sulfur-oxidizing and iron-reducing bacteria (SOIRB) are disclosed. In some embodiments, the methods include the following: providing a SOIRB that have been genetically modified to include a particular metabolic pathway to enable them to generate a biofuel; feeding a first source of ferric iron to the SOIRB; feeding sulfur, water, and carbon dioxide to the SOIRB; producing at least the first particular biofuel, a first source of ferrous iron, sulfate, excess ferric iron, and an SOIRB biomass; electrochemically reducing the excess ferric iron to a second source of ferrous iron; providing an iron-oxidizing bacteria that have been genetically modified to include a particular metabolic pathway to enable them to generate a second biofuel; producing at least the second biofuel, a second source of ferric iron, and an IOB biomass; and feeding the second source of ferric iron to the SOIRB.
    Type: Application
    Filed: February 15, 2013
    Publication date: January 29, 2015
    Inventors: Scott Banta, Alan West, Timothy Kernan
  • Patent number: 8940092
    Abstract: The present invention relates generally to nanocomposite materials. The present invention relates more particularly to hybrid fibers as well as devices including them and methods for making them. Accordingly, one aspect of the invention is a hybrid fiber including a plurality of nanowires, each nanowire having a length, a width, and a thickness, the length being at least 10 times the width and at least 10 times the thickness; and a plurality of binder elements, each binder element having a length, a width, and a thickness, each substantially smaller than the average length of the nanowires and at least one of which is less than about 10 nm in dimension, the binder elements being arranged to intercouple individual nanowires. In certain embodiments, the binder elements are carbon nanotubes, and the nanowires are formed from silicon carbide.
    Type: Grant
    Filed: September 26, 2012
    Date of Patent: January 27, 2015
    Assignee: University of Washington through its Center for Commercialization
    Inventors: Woon-Hong Yeo, Kieseok Oh, Kyong-Hoon Lee, Fong-Li Chou, Jae-Hyun Chung
  • Publication number: 20150004647
    Abstract: A method of producing a sugar solution includes a pretreatment step of treating cellulosic biomass with a treatment agent containing ammonia to obtain an ammonia-treated product, an ammonia-treated sugar solution preparation step of enzymatically saccharifying the ammonia-treated product to obtain an ammonia-treated sugar solution, and a purified sugar solution preparation step of removing coumaramide and/or ferulamide in the ammonia-treated sugar solution by purification to obtain a purified sugar solution having a concentration of coumaramide and/or ferulamide of 10 to 1,100 ppm.
    Type: Application
    Filed: February 12, 2013
    Publication date: January 1, 2015
    Inventors: Masahiro Niwa, Sho Shindo, Takanori Nishida, Junpei Kishimoto, Atsushi Minamino, Hiroyuki Kurihara, Katsushige Yamada
  • Patent number: 8921077
    Abstract: The production of a diutan polysaccharide exhibiting increased viscosity properties as compared with previously produced polysaccharide of the same type of repeating units. Such an improved diutan polysaccharide is produced through the generation of a derivative of Sphingomonas sp. ATCC 53159 that harbors a multicopy broad host range plasmid into which genes for biosynthesis of diutan polysaccharide have been cloned. The inventive methods of production of such an improved diutan polysaccharide, as well as the novel cloned genes required to produce the improved diutan within such a method, are also encompassed within this invention. Additionally, the novel engineered Sphingomonas strain including the needed DNA sequence is encompassed within this invention.
    Type: Grant
    Filed: August 30, 2012
    Date of Patent: December 30, 2014
    Assignee: CP Kelco U.S., Inc.
    Inventors: Nancy E. Harding, Yamini N. Patel, Russell Coleman, Steven Matzke
  • Patent number: 8911970
    Abstract: Fermentation media containing an isoflavone-depleted soybean meal or isoflavone-depleted soybean meal product and at least one exogenous added ingredient that comprises a substrate for microbial growth are provided. Methods of making a fermentation medium comprising an isoflavone-depleted soybean meal or isoflavone-depleted soybean meal product and methods for obtaining a fermentation product are also provided. The present invention is further directed to fermentation broths obtained by the media and methods. The present invention is also directed to feed additives produced from fermentation broths obtained by the methods.
    Type: Grant
    Filed: March 19, 2013
    Date of Patent: December 16, 2014
    Assignee: Fermalogic, Inc.
    Inventor: J. Mark Weber
  • Publication number: 20140363846
    Abstract: The present invention provides a fermentation process for producing a cellulase enzyme mixture comprising the steps of (a) providing a fungal cell of the genus Myceliophthora or a taxonomically equivalent genus; (b) culturing the fungal cell in a submerged liquid batch culture in which the carbon source comprises about 0% of cellulase-inducing carbon source; (c) culturing the fungal cell from the batch culture from step (b) in a submerged liquid fed-batch and/or continuous culture; and (d) providing the culture of step (c) with a feed solution containing a about 100 wt % non-inducing carbon source (such as glucose, dextrose, sucrose, molasses, fructose, glycerol, xylose, or a combination thereof), wherein the feed solution is provided at a rate that maintains the concentration of non-inducing carbon source in the culture below that which would otherwise repress production of the cellulase enzyme mixture, so as to produce a culture filtrate containing at least 10 g protein/L.
    Type: Application
    Filed: August 24, 2012
    Publication date: December 11, 2014
    Applicant: IOGEN ENERGY CORPORATION
    Inventors: Jason B. Edwards, Glenn Munkvold
  • Patent number: 8906651
    Abstract: Isolated polypeptides are disclosed comprising an amino acid sequence encoding a monomer of a fibrous polypeptide attached to a heterologous polysaccharide binding domain. Composites comprising same, methods of generating same and uses thereof are all disclosed.
    Type: Grant
    Filed: April 25, 2013
    Date of Patent: December 9, 2014
    Assignee: CollPlant Ltd.
    Inventors: Oded Shoseyov, Shaul Lapidot, Sigal Meirovitch, Daniel L. Siegel
  • Patent number: 8900839
    Abstract: Biomass (e.g., plant biomass, animal biomass, and municipal waste biomass) is processed to produce useful products, such as fuels. For example, systems are described that can use feedstock materials, such as cellulosic and/or lignocellulosic materials, to produce ethanol and/or butanol, e.g., by fermentation.
    Type: Grant
    Filed: March 13, 2013
    Date of Patent: December 2, 2014
    Assignee: Xyleco, Inc.
    Inventor: Marshall Medoff
  • Publication number: 20140349338
    Abstract: The present invention relates to novel bacteria and the uses thereof. The invention particularly relates to bacteria having a metabolic pathway ratio between Pentose phosphate and glycolysis greater than 0.5, and their uses in the chemical, pharmaceutical or agro-chemical industries, e.g., for producing compounds of industrial interest.
    Type: Application
    Filed: December 21, 2012
    Publication date: November 27, 2014
    Applicant: DEINOVE
    Inventors: Jean-Paul Leonetti, Juha-Pekka Pitkanen, Paula Jouhten
  • Patent number: 8895266
    Abstract: The present invention relates to a cell for the production of an antibody molecule such as an antibody useful for various diseases having high antibody-dependent cell-mediated cytotoxic activity, a fragment of the antibody and a fusion protein having the Fc region of the antibody or the like, a method for producing an antibody composition using the cell, the antibody composition and use thereof.
    Type: Grant
    Filed: November 8, 2012
    Date of Patent: November 25, 2014
    Assignee: Kyowa Hakko Kirin Co., Ltd
    Inventors: Yutaka Kanda, Mitsuo Satoh, Kazuyasu Nakamura, Kazuhisa Uchida, Toyohide Shinkawa, Naoko Yamane, Emi Hosaka, Kazuya Yamano, Motoo Yamasaki, Nobuo Hanai