Streptococcus Patents (Class 435/253.4)
  • Patent number: 10849925
    Abstract: The present invention concerns a process for the preparation and purification of the sodium salt of HA from the fermentation broth of Streptococcus or Bacillus or from rooster combs, the sodium salt of HA obtained and purified with said process and pharmaceutical, cosmetic and nutritional compositions comprising said sodium salt of HA.
    Type: Grant
    Filed: July 27, 2017
    Date of Patent: December 1, 2020
    Assignee: FIDIA FARMACEUTICI S.P.A.
    Inventors: Mara Pittarello, Francesco Borile, Vincenza Corsa
  • Patent number: 9155766
    Abstract: Disclosed herein are probiotic compositions comprising a mixture of at least two probiotic bacteria, including Streptococcus salivarius K12® (BLIS K12®) and at least a Lactobacillus bacteria. The Streptococcus salivarius K12® (BLIS K12®) may comprise Streptococcus salivarius K12® (BLIS K12®) BAA1024. The Lactobacillus bacteria may be selected from those known to be suitable for oral administration, for example from those known to improve recipient health, particularly recipient oral health.
    Type: Grant
    Filed: July 22, 2013
    Date of Patent: October 13, 2015
    Assignee: Integra Medical Inc.
    Inventor: Natalya Ioudina
  • Publication number: 20150147436
    Abstract: The present invention provides methods, compositions, and systems for producing cheese with S. thermophilus and a urease inhibitor, and for producing cottage cheese with S. thermophilus that is partially or completely deficient in its ability to release ammonia from urea. The present invention also provides methods, compositions, and systems for reducing the amount of open texture (e.g., slits, cracks, or fractures) in gassy cheeses, such as cheddar cheese.
    Type: Application
    Filed: January 9, 2015
    Publication date: May 28, 2015
    Inventor: Lars W. Petersen
  • Patent number: 9040302
    Abstract: Methods and compositions for targeted delivery of biotherapeutics are provided. The compositions comprise bile-sensitive St. thermophilus bacteria modified to release a biotherapeutic agent following bile exposure. Biotherapeutic agents released by the St. thermophilus bacteria disclosed herein include AQ and AQR rich peptides. Methods of the invention comprise administering to a subject a St. thermophilus bacterium modified to release a biotherapeutic agent following bile exposure. Administration of the St. thermophilus bacterium promotes a desired therapeutic response. The bacterium may be modified to express and release AQ or AQR rich peptides which subsequently inhibit cellular apoptosis or reduce mucosal damage. Thus, methods of the invention find use in treating or preventing a variety of gastrointestinal disorders including C. difficile infection and antibiotic-associated diarrhea.
    Type: Grant
    Filed: May 19, 2011
    Date of Patent: May 26, 2015
    Assignees: North Carolina State University, University of Virginia Patent Foundation
    Inventors: Todd R. Klaenhammer, Richard L. Guerrant, Glynis L. Kolling, Evelyn Durmaz, Michael P. Timko, Cirle Alcantara Warren
  • Publication number: 20150132740
    Abstract: A concentration agent for microorganisms is provided that contains both lanthanum and carbonate. Additionally, articles that include the concentration agent and methods of concentrating a microorganism using the concentration agent are provided.
    Type: Application
    Filed: May 23, 2013
    Publication date: May 14, 2015
    Inventors: Manjiri T. Kshirsagar, Evan Koon Lun Yuuji Hajime, Andrew W. Rabins
  • Publication number: 20150125895
    Abstract: Various embodiments disclosed herein provide for reagents and methods for rapidly isolating viable microbial cells, including S. pneumoniae, from positive blood culture samples. The resulting microbial pellet can be used for both identification and growth-based methods such as antimicrobial susceptibility testing. The buffers described herein may contain a base solution, non-ionic detergents, thiols, and optionally, ammonium chloride. The disclosed methods provide a process for rapidly isolating and concentrating viable microorganism (s) from PBC samples using only one sample preparation tube and centrifugation while removing cellular debris from the mammalian blood cells that may interfere with identification methods.
    Type: Application
    Filed: February 28, 2013
    Publication date: May 7, 2015
    Applicant: Becton, Dickinson and Company
    Inventors: Susan M. Kircher, Vanda White, William B. Brasso, Dyan Luper, James Y. Zhou, Julie L. Rosales, Jeffery H. Bruton, John D. Mantlo, Adrien P. Malick, Donald R. Callihan, Ben Turng, Liping Feng, Curtis M. Gosnell, Patrick Shawn Beaty, John P. Douglass
  • Publication number: 20150098929
    Abstract: A probiotic organism which is capable of proliferation in iron-rich media, an environment which is generally unfavourable to probiotic organisms, is described.
    Type: Application
    Filed: July 19, 2012
    Publication date: April 9, 2015
    Applicant: THE UNIVERSITY OF BRISTOL
    Inventors: Tristan Cogan, Jenny Bailey
  • Publication number: 20150099273
    Abstract: The present invention relates to a bacterial cell with texturizing property, starter cultures comprising the cell, and dairy products fermented with the starter culture.
    Type: Application
    Filed: September 29, 2014
    Publication date: April 9, 2015
    Applicant: CHR. HANSEN A/S
    Inventors: Thomas JANZEN, Ditte Ellegaard CHRISTIANSEN
  • Publication number: 20150087614
    Abstract: Provided herein are methods for inducing cell death in a gram positive bacterium and methods for reducing the proliferation of a gram positive bacterium that include contacting a gram positive bacterium with a dye (e.g., an azo dye) and a TarO inhibitor. Also provided are methods of treating a subject having a gram positive bacterial infection that include administering to a subject having a gram positive bacterial infection a dye (e.g., an azo dye) and a TarO inhibitor. Also provided are compositions containing a dye (e.g., an azo dye) and a TarO inhibitor, and kits containing at least one of these compositions.
    Type: Application
    Filed: March 14, 2013
    Publication date: March 26, 2015
    Inventors: Michael S. Gilmore, Takashi Suzuki
  • Patent number: 8986973
    Abstract: Provided is a Streptococcus dysgalactiae ID9103 strain having accession number KCTC11818BP, and a method of producing hyaluronic acid by culturing the strain to produce hyaluronic acid having an average molecular weight of 10,000,000 Da or more.
    Type: Grant
    Filed: March 26, 2014
    Date of Patent: March 24, 2015
    Assignee: Ildong Pharm Co., Ltd.
    Inventors: Dae-Jung Kang, Jong-Hyuk Im, Tae-Yoon Kim, Jae-Hoon Kang
  • Publication number: 20150072033
    Abstract: The present invention generally relates to the field of pro biotic micro-organisms, in particular to the field of non-replicating probiotic micro-organisms. Embodiments of the present invention relate to compositions comprising probiotic microorganisms that were rendered non-replicating by extrusion. Such compositions may be used to treat or prevent disorders that are related to a compromised immune system.
    Type: Application
    Filed: November 14, 2014
    Publication date: March 12, 2015
    Inventors: Annick Mercenier, Antoine Wermeille, Audrey Demont, Guenolee Prioult
  • Patent number: 8945533
    Abstract: The object of the present invention is to provide an oral cavity composition which is nontoxic, excellent in plaque control, can prevent or treat onset of caries and periodontal disease caused by oral pathogens as well as can prevent or eliminate bad breath. The invention provides an oral cavity composition containing a lactic acid bacterium, Streptococcus faecalis as an active ingredient, the oral cavity composition wherein the lactic acid bacterium, Streptococcus faecalis is Streptococcus faecalis WB2000 strain and the oral cavity composition which is a non-aqueous oral cavity composition.
    Type: Grant
    Filed: November 14, 2006
    Date of Patent: February 3, 2015
    Assignees: Nippon Zettoc Co., Ltd., Wakamoto Pharmaceutical Co., Ltd.
    Inventors: Keiichiro Kondo, Misao Yasumuro, Seigo Nakaya, Nobuyuki Suzuki
  • Publication number: 20140335227
    Abstract: The present invention provides a process for the preparation of freeze dried microorganism composition, comprising the step of (i) subjecting a frozen composition comprising micro-organisms to a drying pressure of from 133 Pa [1000 mT] to 338 Pa [2540 mT] such that at the drying pressure the frozen composition is dried by sublimation of water present in the frozen composition to provide a freeze dried composition comprising the micro-organisms.
    Type: Application
    Filed: December 7, 2012
    Publication date: November 13, 2014
    Inventors: Christophe Hollard, Ronald Agee
  • Publication number: 20140322718
    Abstract: The present invention concerns a new competence stimulating peptide identified in Firmicutes, in particular Streptococcus, and more preferably S. thermophilus and methods of producing transformation competent Firmicutes, in particular Streptococcus, and more preferably S. thermophilus bacteria.
    Type: Application
    Filed: July 9, 2014
    Publication date: October 30, 2014
    Inventors: Rozenn GARDAN, Veronique MONNET
  • Patent number: 8865156
    Abstract: The invention provides compositions comprising one or more isolated LDH-deficient mutans streptococcus strains and one or more isolated S. oralis strains and/or one or more isolated S. uberis strains. Compositions of the invention are useful to maintain oral health, by for example treating and/or preventing one or more symptoms of dental caries, periodontitis and/or other oral cavity diseases or wounds.
    Type: Grant
    Filed: January 31, 2011
    Date of Patent: October 21, 2014
    Assignee: Oragenics, Inc.
    Inventor: Jeffrey D. Hillman
  • Publication number: 20140301994
    Abstract: The invention relates to an anhydrous mixture of biologically active probiotic bacteria for topical administration and methods of making thereof. The mixture of the invention is used for hydrating the skin, reducing and preventing fine lines and wrinkles, treating acne and decreasing skin inflammation.
    Type: Application
    Filed: November 1, 2012
    Publication date: October 9, 2014
    Inventors: Andrew M. Klapper, Spencer J. Malkin
  • Patent number: 8852584
    Abstract: The bacteriolytic effect of a bacterial cell wall lytic enzyme can be increased by the addition of a surfactant to the enzyme. As a result, the time required for lysis of cariogenic bacterium with the bacterial cell wall lytic enzyme can be shortened, and the practical utility of the bacterial cell wall lytic enzyme (such as automutanolysin) as a prophylactic or therapeutic agent for dental caries can be improved.
    Type: Grant
    Filed: July 25, 2006
    Date of Patent: October 7, 2014
    Assignee: Two Cells Co., Ltd.
    Inventors: Motoyuki Sugai, Hitoshi Komatsuzawa
  • Publication number: 20140220663
    Abstract: The present invention provides a method for reducing the viscosity of a microorganism-containing suspension or concentrate and a method for obtaining a microorganism concentrate, wherein a monosaccharide and/or disaccharide and/or sugar alcohol is added to said microorganism-containing suspension or concentrate.
    Type: Application
    Filed: July 6, 2012
    Publication date: August 7, 2014
    Applicant: DUPONT NUTRITION BIOSCIENCES APS
    Inventors: Michel Cadenel, Patrick Chaigneau, Guy D'angloz, Erwan Henri, Jean Pierre Rocher
  • Publication number: 20140205693
    Abstract: The present invention relates to an extract from bacterial strains, such as Staphylococcus, Moraxella, Klebsiella, Streptococcus, and Haemophilus. The extract is useful as a treatment for indications such as respiratory disorders, compositions comprising the extract, and processes of making the extract from media that do not pose a risk of prion diseases.
    Type: Application
    Filed: March 20, 2014
    Publication date: July 24, 2014
    Applicant: OM PHARMA SA
    Inventors: Jacques Alain BAUER, Marco SALVAGNI, Jean-Pierre Leon VIGROUX, Laetitia CHALVET, Carlo CHIAVAROLI
  • Publication number: 20140206067
    Abstract: The present invention relates to a process for providing purified bacteria-containing concentrates, comprising at least the steps of adding an aqueous solution to a first bacteria-containing concentrate to provide a bacteria-containing suspension, wherein the volume of the added aqueous solution is in the range of 0.3 liters to 10 liters per liter of said first bacteria-containing concentrate; and concentrating said bacteria-containing suspension to provide a second bacteria-containing concentrate. Further, the present invention relates to the purified concentrates per se.
    Type: Application
    Filed: August 20, 2012
    Publication date: July 24, 2014
    Applicant: CHR. HANSEN A/S
    Inventors: Tania Ivanova Georgieva, Anders Clausen, Tina Malling Thorsen
  • Publication number: 20140206040
    Abstract: Provided is a Streptococcus dysgalactiae ID9103 strain having accession number KCTC11818BP, and a method of producing hyaluronic acid by culturing the strain to produce hyaluronic acid having an average molecular weight of 10,000,000 Da or more.
    Type: Application
    Filed: March 26, 2014
    Publication date: July 24, 2014
    Applicant: ILDONG PHARM CO., LTD.
    Inventors: Dae-Jung KANG, Jong-Hyuk IM, Tae-Yoon KIM, Jae-Hoon Kang
  • Patent number: 8778657
    Abstract: The present invention discloses culture medium unit doses for cultivating microorganisms comprising at least two compositions, each composition packaged in a composition unit dose of a predetermined amount, the composition unit doses being used for combining one of each composition unit dose forming the culture medium unit dose. The composition unit doses being packaged separately and individually until a time the culture medium unit dose is to be prepared for use for cultivation of microorganisms, wherein the time one of each composition unit dose are combined thereby forming the culture medium unit dose. The invention also discloses a method of manufacturing the composition unit doses, and a kit for cultivating microorganisms, the kit comprising a combination of the composition unit doses.
    Type: Grant
    Filed: October 17, 2012
    Date of Patent: July 15, 2014
    Assignee: Hardy Diagnostics
    Inventors: Gary A. Peterson, Andre Y. Hsiung
  • Patent number: 8771766
    Abstract: The invention relates to a genetic cluster of strains of S. thermophilus, wherein the milk fermented with said strains is highly viscous and weakly ropy. The invention also relates to a genetic cluster of strains of S. thermophilus, wherein the genome of said strains comprises a CRISPR locus having the nucleotide sequence of SEQ ID No 1.
    Type: Grant
    Filed: December 14, 2009
    Date of Patent: July 8, 2014
    Assignee: Dupont Nutrition Biosciences APS
    Inventors: Elise Manoury, Philippe Horvath, Christophe Fremaux, Pascal Fourcassie
  • Publication number: 20140178313
    Abstract: Provided is a novel lactic acid bacterium strain which is capable of suppressing production of volatile sulfur compounds by oral bacteria, has no cariogenicity and no causative role in infective endocarditis, and is safe in an oral cavity, and provided is an agent for preventing, improving and/or treating oral diseases and discomforts by use of the bacterial strain.
    Type: Application
    Filed: August 3, 2012
    Publication date: June 26, 2014
    Applicant: KABUSHIKI KAISHA YAKULT HONSHA
    Inventors: Takekazu Okumura, Tomohiko Terai, Masumi Nakao, Kimiyuki Kaneko, Masahiko Ito, Kouji Miyazaki, Kazuaki Yamaji, Kaoru Tochiya, Nobuhiro Hanada, Susumu Imai, Yoshiaki Nomura, Shunsuke Baba
  • Publication number: 20140161781
    Abstract: The invention relates to a zinc-enriched biomass comprising living or subsequently killed micro-organisms, selected from the group consisting of Streptococcus thermophilus and Bifidobacterium animalis subsp. lactis and combinations thereof, a method for the manufacture of said zinc-enriched biomass, as well as food preparations, nutraceutic products, functional foods, cosmetic and cosmeceutic products, and food supplements, comprising the said biomass. Furthermore, new micro-organism strains are described which are able to concentrate zinc within the cell in very high amounts and therefore are particularly suitable for use in the method of the invention.
    Type: Application
    Filed: November 4, 2013
    Publication date: June 12, 2014
    Inventors: Alberto BENEDETTI, Francesco GIRARDO
  • Publication number: 20140147426
    Abstract: The present invention discloses different specific bacterial strains isolated from individuals without caries which are characterised in that they present inhibitory activity against cariogenic organisms. The invention also discloses a process for isolating said strains, as well as bioactive peptides, such as anti-microbial peptides of human and bacterial origin, which also show anti-cariogenic activity. Moreover, the present invention also discloses pharmaceutical and/or probiotic/prebiotic compositions, functional foods, mouthwashes, toothpaste, chewing gum, etc., that comprise at least one of the strains and/or at least one of the bioactive peptides described in the invention, or a combination thereof, which are useful in the treatment and/or prevention of infectious diseases of the buccal cavity, preferably caries.
    Type: Application
    Filed: August 31, 2011
    Publication date: May 29, 2014
    Applicant: CENTRO SUPERIOR DE INVESTIGACION EN SALUD PUBLICA (CSISP)
    Inventor: Alejandro Mira Obrador
  • Patent number: 8728490
    Abstract: Described are Streptococcus suis infections in pigs, vaccines directed against those infections and tests for diagnosing S. suis infections. Provided is an isolated or recombinant nucleic acid encoding a capsular gene cluster of S. suis or a gene or gene fragment derived therefrom. Further provided is a nucleic acid probe or primer allowing species or serotype-specific detection of S. suis. Also provided is a Streptococcus suis antigen and vaccine derived therefrom.
    Type: Grant
    Filed: June 16, 2010
    Date of Patent: May 20, 2014
    Assignee: Stichting Dienst Landbouwkundig Onderzoek
    Inventor: Hilda Elizabeth Smith
  • Patent number: 8728461
    Abstract: A novel lactic acid bacterium strain is found, which has a high IgA production-inducing ability and a high immunostimulating activity, and belongs to the genus Enterococcus. Thus, provided is an excellent lactic acid bacterium preparation for foods or feeds, which has a high enteric colonization rate. Specifically disclosed are: a novel lactic acid bacterium Enterococcus faecium NHRD IHARA (FERM BP-11090) which has a high IgA production-inducing ability and a high immunostimulating activity; and a lactic acid bacterium preparation for enhancing the production of immunoglobulin A, which comprises a culture of the bacterium strain, an extract of the bacterium strain, or a product of any treatment of cells of the bacterium strain.
    Type: Grant
    Filed: March 30, 2009
    Date of Patent: May 20, 2014
    Assignee: Nippon Meat Packers, Inc.
    Inventors: Yasuhiro Ihara, Hiroshi Murakami, Yoichi Takahagi
  • Publication number: 20140134292
    Abstract: The present invention provides methods, compositions, and systems for producing cheese with S. thermophilus and a urease inhibitor, and for producing cottage cheese with S. thermophilus that is partially or completely deficient in its ability to release ammonia from urea. The present invention also provides methods, compositions, and systems for reducing the amount of open texture (e.g., slits, cracks, or fractures) in gassy cheeses, such as cheddar cheese.
    Type: Application
    Filed: January 12, 2012
    Publication date: May 15, 2014
    Applicant: DUPONT NUTRITION BIOSCIENCES APS
    Inventor: Lars Wexoe Petersen
  • Publication number: 20140134295
    Abstract: The present invention relates to peptides, nucleic acids and methods for transforming a bacterium belonging to the Streptococcus genus by natural competence and their use in the food and feed industry.
    Type: Application
    Filed: January 23, 2014
    Publication date: May 15, 2014
    Inventors: Patrick Boyaval, Christophe Fremaux, Pascal Hols, Laetitia Fontaine, Philippe Horvath
  • Publication number: 20140113028
    Abstract: A process for the manufacture of a fermented dairy product comprising (a) subjecting a milk base to fermentation with a starter comprising of a weakly post-acidifying bacterial culture, until a desired pH value in the range of 4.0 and 5.0 is reached (end of fermentation), (b) optionally cooling the fermented milk base obtained in step (a); and (c) packaging the fermented dairy product.
    Type: Application
    Filed: May 15, 2012
    Publication date: April 24, 2014
    Applicant: DSM IP ASSETS B.V.
    Inventor: Paul Gerard Bruinenberg
  • Patent number: 8637049
    Abstract: Safe and effective live vaccines against bacteria infecting aquatic animals were created through the induction of novobiocin-resistance in liquid culture and novobiocin- and rifampicin-resistance in liquid culture.
    Type: Grant
    Filed: April 6, 2011
    Date of Patent: January 28, 2014
    Assignee: The United States of America, as represented by the Secretary of Agriculture
    Inventors: Yuping Wei Pridgeon, Phillip H. Klesius
  • Publication number: 20140017767
    Abstract: The present invention relates to microbial inocula and in particular to standardised inocula for producing reference cultures of microorganisms. The invention has been developed primarily for use as a solid, disc-shaped, inoculum and will be described hereinafter with reference to this application. However, it will be appreciated that the invention is not limited to this particular field of use.
    Type: Application
    Filed: June 21, 2013
    Publication date: January 16, 2014
    Applicant: AMS Laboratories Pty Ltd
    Inventors: Paul PRISCOTT, Yi-hong WANG
  • Publication number: 20140011183
    Abstract: This invention is in the field of bacterial cultures and specifically relates to the optimization of culture conditions to improve the production of bacterial capsular polysaccharides from Streptococcus strains in fed batch culture and to novel purification methods suitable for production scale purification of bacterial capsular polysaccharides from Streptococcus strains resulting in higher levels of purity than previously obtained for production scale.
    Type: Application
    Filed: March 7, 2013
    Publication date: January 9, 2014
    Inventors: Paolo COSTANTINO, Francesco NORELLI, Francesco BERTI, Roberto OLIVIERI, Giulia BAZZOCCHI, Concetta CICALA, Silvia FONTANI
  • Publication number: 20140004144
    Abstract: The present invention provides attenuated S. suis strains that elicit an immune response in animal S. suis, compositions comprising said strains, methods of vaccination against S. suis, and kits for use with such methods and compositions. The invention further provides novel, mutagenically-induced mutations in S. suis genes, which are useful in the production of novel attenuated S. suis bacterial strains.
    Type: Application
    Filed: June 24, 2013
    Publication date: January 2, 2014
    Applicant: MERIAL LIMITED
    Inventors: Russell F Bey, Paulraj Kirubakaran Lawrence, Randy R Simonson, Kamesh Reddy Sirigireddy, Danielle A McKeown
  • Publication number: 20130337546
    Abstract: A process for concentrating microorganism-containing suspensions comprising (a) centrifuging a microorganism-containing suspension to provide a first microorganism-containing concentrate and a supernatant liquid; (b) filtering said first microorganism-containing concentrate, to provide a permeate and a second microorganism-containing concentrate.
    Type: Application
    Filed: August 21, 2013
    Publication date: December 19, 2013
    Applicant: Danisco A/S
    Inventors: Lars Wexoe Petersen, Eric Hohol, Steve E. von Dollen
  • Patent number: 8597638
    Abstract: The invention relates to a zinc-enriched biomass comprising living or subsequently killed micro-organisms, selected from the group consisting of Streptococcus thermophilus and Bifidobacterium animalis subsp. lactis and combinations thereof, a method for the manufacture of said zinc-enriched biomass, as well as food preparations, nutraceutic products, functional foods, cosmetic and cosmeceutic products, and food supplements, comprising the said biomass. Furthermore, new micro-organism strains are described which are able to concentrate zinc within the cell in very high amounts and therefore are particularly suitable for use in the method of the invention.
    Type: Grant
    Filed: July 22, 2008
    Date of Patent: December 3, 2013
    Assignee: Bioman S.R.L.
    Inventors: Alberto Benedetti, Francesco Girardo
  • Publication number: 20130315958
    Abstract: Disclosed is a new and emerging serotype of Streptococcus pneumoniae designated serotype 6C, and assays and monoclonal antibodies useful in identifying same. Also disclosed is a novel pneumococcal polysaccharide with the repeating unit {2) glucose 1 (1?3) glucose 2 (1?3) rhamnose (1?3) ribitol (5?phosphate}. This new serotype may be included in pneumococcal vaccines.
    Type: Application
    Filed: May 9, 2013
    Publication date: November 28, 2013
    Inventors: Moon H. Nahm, Jisheng Lin, Angela P. Brandao, Maria Cristina Brandileone
  • Publication number: 20130309754
    Abstract: Culturally modified lactic acid bacterial cells containing a porphyrin compound and their use in a novel method of reducing the oxygen content in a food and feed product or starting material is provided and means of improving the shelf life and/or quality of such products by using the culturally modified bacterial cells. Such culturally modified cells are useful in the manufacturing of a food and a feed product and for the manufacturing of metabolites produced by modified cells.
    Type: Application
    Filed: June 13, 2013
    Publication date: November 21, 2013
    Applicant: CHR. HANSEN A/S
    Inventors: Geppel ASGER, Borge Windel KRINGELUM, Ken Flemming HANSEN, Stig Lykke IVERSEN, Claus Maxel HENRIKSEN
  • Publication number: 20130288340
    Abstract: An object of the present invention is to provide a microorganism which is novel at the elemental composition level, and to provide a technique for providing such a microorganism. The present inventor has succeeded in causing a microorganism to efficiently contain a non-essential element by decreasing the content of an essential nutrient source for the microorganism, a C source, an N source, a P source, or an S source, and by adding an X compound containing the non-essential element as a constitutive element in a manner to make up for the decreased amount, and then culturing the microorganism.
    Type: Application
    Filed: September 5, 2011
    Publication date: October 31, 2013
    Applicants: PARA MICROBIOS LABORATORIES LLC
    Inventor: Yoshitake Tanaka
  • Patent number: 8529887
    Abstract: The present invention relates generally to the field of nutrition, more particularly to the use of probiotics in nutrition. In particular the present invention relates to the use of a probiotic or of a mixture of probiotics in the manufacture of a nutritional composition or a medicament to act the colon in a pre- or post surgical environment.
    Type: Grant
    Filed: May 14, 2008
    Date of Patent: September 10, 2013
    Assignee: Nestec S.A.
    Inventor: Eduardo Schiffrin
  • Publication number: 20130230611
    Abstract: The present invention generally relates to the field of probiotic micro-organisms, in particular to the field of non-replicating probiotic micro-organisms. Embodiments of the present invention relate to compositions comprising probiotic micro-organisms that were rendered non-replicating by extrusion. Such compositions may be used to treat or prevent disorders that are related to a compromised immune system.
    Type: Application
    Filed: November 11, 2011
    Publication date: September 5, 2013
    Applicant: NESTEC S.A.
    Inventors: Annick Mercenier, Antoine Wermeille, Audrey Demont, Guenolee Prioult
  • Patent number: 8518688
    Abstract: The present invention discloses culture medium unit doses for cultivating microorganisms comprising at least two compositions, each composition packaged in a composition unit dose of a predetermined amount, said composition unit doses being used for combining one of each composition unit dose forming said culture medium unit dose. The composition unit doses being packaged separately and individually until a time said culture medium unit dose is to be prepared for use for cultivation of microorganisms, wherein said time one of each composition unit dose are combined thereby forming said culture medium unit dose. The invention also discloses a method of manufacturing the composition unit doses, and a kit for cultivating microorganisms, the kit comprising a combination of the composition unit doses.
    Type: Grant
    Filed: October 17, 2012
    Date of Patent: August 27, 2013
    Assignee: Hardy Diagnostics
    Inventors: Gary A. Peterson, Andre Y. Hsiung
  • Publication number: 20130216576
    Abstract: Disclosed is a new and emerging serotype of Streptococcus pneumoniae designated serotype 6D, and assays and monoclonal antibodies useful in identifying same. Also disclosed is a novel pneumococcal polysaccharide with the repeating unit?2) glucose 1 (1?3) glucose 2 (1?3) rhamnose (1?4) ribitol (5?phosphate. This new serotype may be included in pneumococcal vaccines.
    Type: Application
    Filed: April 19, 2013
    Publication date: August 22, 2013
    Applicant: UAB Research Foundation
    Inventor: UAB Research Foundation
  • Patent number: 8501456
    Abstract: A method for making at least 2 kg (dry weight) of a lactic acid bacteria composition formulated with from 1% to 50% of ascorbate or ascorbic acid (w/w?dry matter) as antioxidant, wherein the pH is controlled so 3?pH?8 during at least the majority of the fermentation process by addition of a base not comprising NH3 (ammonia).
    Type: Grant
    Filed: February 18, 2010
    Date of Patent: August 6, 2013
    Assignee: CHR. Hansen A/S
    Inventors: Birgitte Yde, Susanne Abrahamsen
  • Patent number: 8481025
    Abstract: The present invention provides a composition comprising prebiotic and probiotic components and is used to reduce elevated levels of nitrogenous waste products and to promote a healthy bowel microenvironment.
    Type: Grant
    Filed: September 4, 2012
    Date of Patent: July 9, 2013
    Assignee: Kibow Biotech, Inc.
    Inventor: Natarajan Ranganathan
  • Patent number: 8481027
    Abstract: A stable, pellet-frozen lactic acid bacteria (LAB) culture comprises at least one additive compound in a commercial relevant package. The pellet-frozen culture has at least 50 g frozen material and a content of viable bacteria of at least 109 colony forming units per gram of frozen material. The individual pellets of the frozen culture do not stick together and remain as individual pellets, when stored at about ?46° C., for at least 7 to 14 days.
    Type: Grant
    Filed: July 15, 2010
    Date of Patent: July 9, 2013
    Assignee: Chr. Hansen A/S
    Inventors: Rikke Stavnsbjerg, Inge Knap, Hans Bisgaard-Frantzen, Borge Windel Kringelum
  • Publication number: 20130164408
    Abstract: The present invention relates to a method for obtaining a lactic acid bacteria strain which results in a high mechanical shear resistance of the products fermented with the strain and to bacteria strains obtainable by such a method. Furthermore, the present invention relates to lactic acid bacteria strains which results in a high resistance towards mechanical shear treatment of the products fermented with the strains or mutants and variants thereof. The improved stability of the texture can be measured as reduced sedimentation in drinking yoghurt applications and reduced syneresis in set-type yoghurt applications. Thus, the present invention also relates to methods for preparation of a fermented milk product, such as a yoghurt, with such lactic acid bacteria strains and to such fermented milk products.
    Type: Application
    Filed: June 21, 2011
    Publication date: June 27, 2013
    Inventors: Ditte Marie Folkenberg, Christian Gilleladen, Helle Skov Guldager
  • Publication number: 20130095044
    Abstract: A new microbial strain of the species Streptococcus salivarius for use in the treatment of inflammatory processes with or without infectious etiology. A further object of the present invention compositions including the strain and uses thereof.
    Type: Application
    Filed: October 4, 2012
    Publication date: April 18, 2013
    Applicant: D.M.G. ITALIA Srl
    Inventor: D.M.G. ITALIA Srl
  • Patent number: RE45170
    Abstract: The invention relates to Streptococcus suis infection in pigs, vaccines directed against those infections and tests for diagnosing Streptococcus suis infections. The invention provides an isolated or recombinant nucleic acid encoding a capsular gene cluster of Streptococcus suis or a gene or gene fragment derivated thereof. The invention further provides a nucleic acid probe or primer allowing species or serotype-specific detection of Streptococcus suis. The invention also provides a Streptococcus suis antigen and vaccine derived thereof.
    Type: Grant
    Filed: August 30, 2013
    Date of Patent: September 30, 2014
    Assignee: Stichting Dienst Landbouwkundig Onderzoek
    Inventor: Hilda Elizabeth Smith