Abstract: Procedures are disclosed for eliminating immune competent cells from a population of human epidermal cells. The cells free of immune competent cells are used for growing tissue sheets suitable for transplantation to recipients unrelated to the donor.

Abstract: Waste water and/or outgoing air are purified by contact with a polyurethane hydrogel containing surface active coal, a polymer having cationic groups and cells having enzymatic activity and being capable of growth.

Abstract: A biologically active composition is prepared comprising a polyurethane hydrogel containing surface active coal, a polymer having cationic groups and cells having enzymatic activity and being capable of growth. The composition is used for purifying waste water and outgoing air.

Abstract: A partially purified proteinaceous bone-inducing factor of 10,000 to 30,000 daltons is described. It is derived from demineralized bovine bone by extraction with a chaotropic agent, gel filtration, cation exchange chromatography using carboxymethyl cellulose at pH 4.8 and gradient elution with NaCl at 10 mM to about 150 mM.

Abstract: A method and device is disclosed for the release and separation of substances such as parasites or parasite eggs from meat. In the method, meat is agitated with pepsin and filtered through a series of at least two filters, the last of which retains the parasites or parasite eggs. The device includes a reactor which tapers downwardly, and which has in its lower part an outlet valve connected via a conically widening part with a separator device. The separator device includes a cylindrical connecting piece which accepts holder rings for holding one or more filters or sieves in releasable connection.

Abstract: A process for the preparation of fish and/or shellfish extracts having various pharmaceutical functions is provided. The process comprises decomposing raw fish and/or shellfish at a pH of 6.0 to 7.0 with a Bacillus subtilis derived proteinase and decomposing at the same pH range with a Koji mould derived proteinase. The product extracts contain peptide amino acids each having a molecular weight of substantially less than 3000 and free amino acids. According to the invention, medicines containing the fish and/or shellfish extracts are also provided such as nutrition balancing medicines, anti-ulcer medicines, diabetes relieving medicines, antilipemic medicines and rheumatism and arthritis relieving medicines.

Abstract: The invention relates to a device useful when installed in a urinal for collection of urinary proteins. The adsorbent means includes a conduit for gravity feed passage of urine streams. The conduit has permeable layers in series containing a slow releasing antimicrobial agent and an adsorbent for urinary proteins such that for collection puropses wanted proteins are adsorbed without odor or loss due to bacterial degradation.

Abstract: The invention relates to a method for hydrolyzing drug-glucuronic acid conjugates present in mammalian body fluids, the conjugates being derived from a narcotic analgesic, antagonist, or agonist-antagonist whose metabolism includes conjugation with glucuronic acid. The method comprises incubating the body fluid sample at from about 60.degree. to about 70.degree. C., for at least about 1 hour, with .beta.-glucuronidase derived from Patella vulgata, and substantially increases the sensitivity of chromatographic techniques for the detection of morphine and its analogues.

Abstract: Cultivation of phototrophic bacteria such as in the treatment of organic wastes is carried out in a light field substantially free from ultraviolet light having a wavelength of not more than 340 nm. This process promotes growth of the phototrophic bacteria and improves quality of the resulting bacterial cell.

Abstract: A fibrous tissue preparation suitable for homo or heterotransplantation is obtained by treating mammalian fibrous tissue with a proteolytic enzyme followed, if desired, by further treatment with a carbohydrate splitting enzyme.

Abstract: A process for making factor for stimulating the rate of proliferation of liver cells comprising homogenizing animal Peyer's glands, adjusting pH to about 5.5, thermally denaturing the product and recovering the desired factor in the supernatant by centrifugation.

Abstract: Novel hemostatic agent comprises equine arterial fibrillar collagen in a carrier. The agent is useful for the aggregation of platelets for clinical diagnostic tests and for the clotting of blood, such as for controlling bleeding in warm blooded species. The fibrillar collagen is obtained by extracting homogenized equine arterial tissue with aqueous solutions followed by extensive dialysis.

Abstract: Growth and proliferation of bacteria may be inhibited in urine stored in a urine drainage container by placing urease in the container to generate sufficient ammonia to elevate the pH thereof to an alkaline level unfavorable for supporting microbial growth. Preferably, the urease is sealed in envelope means of semipermeable membrane which is capable of allowing diffusion of urea from urine stored in the container, while preventing substantial diffusion of the urease outwardly from the envelope means. Accordingly, the urease remains indefinitely reusable over many fillings and drainings of the container.

Abstract: A novel methylguanidine-decomposing enzyme can be obtained by cultivating in a medium a bacterium belonging to Genus Alcaligenes and having an ability to produce a methylguanidine-decomposing enzyme. This methylguanidine-decomposing enzyme has an ability to decompose methylguanidine into methylamine and urea. Its optimum pH range is 10.9-12.3 and its stable pH range is 5.0-10.6.

Abstract: Urea such as that present in dialysates is converted to inocuous products by employing a culture having the identification ATCC 31381 or one of its primary cultures or mixtures thereof.

Abstract: Protease inhibitor is extracted from fresh or frozen organs of slaughtered animals by an enzymolysis operation which excludes any possibility of interference by azymic autolysis, the enzymolysis being stopped after a time not exceeding 4 hours, whereafter a lysate aqueous solution is obtained by filtration and a quaternary ammonium base is added to the lysate solution to precipitate insolubles, the filtrate being the fraction which contains the expected protease inhibitor.