Abstract: A novel soybean variety, designated 95Y21 is provided. Also provided are the seeds of soybean variety 95Y21, cells from soybean variety 95Y21, plants of soybean 95Y21, and plant parts of soybean variety 95Y21. Methods provided include producing a soybean plant by crossing soybean variety 95Y21 with another soybean plant, methods for introgressing a transgenic trait, a mutant trait, and/or a native trait into soybean variety 95Y21, methods for producing other soybean varieties or plant parts derived from soybean variety 95Y21, and methods of characterizing soybean variety 95Y21. Soybean seed, cells, plants, germplasm, breeding lines, varieties, and plant parts produced by these methods and/or derived from soybean variety 95Y21 are further provided.

Abstract: Compositions and methods relating to the use of sulfonylurea-mediated control of gene expression are provided. Compositions include sulfonylurea responsive chemical switches wherein the gene expression is regulated by a sulfonylurea compound. Compositions also include polynucleotides encoding the polypeptides as well as constructs, vectors, prokaryotic and eukaryotic cells, and eukaryotic organisms including plants and seeds comprising the polynucleotide, and/or produced by the methods. Also provided are methods to regulate expression of a polynucleotide of interest in a cell or organism, and methods to modify a genome, including in a plant or plant cell.

Abstract: Recombinant microorganisms, plants, and plant cells are disclosed that have been engineered to express a mutant AROM polypeptide and/or mutant catechol-O-methyltransferase polypeptide alone or in combination with one or more vanillin biosynthetic enzymes or UDP-glycosyltransferases (UGTs). Such microorganisms, plants, or plant cells can produce vanillin or vanillin beta-D-glucoside.

Abstract: The present invention provides metabolic regulators, which are proteins (such as fusion proteins, truncated proteins or full-length proteins) that bind to specific metabolites and which can be used to control the availability of the metabolites in cells, particularly plant cells. Proteins of the invention include one or more metabolic regulator proteins, can be truncated or full length, can further comprise a transmembrane domain or lipoylation site or can further comprise a transit peptide. Metabolic regulators of the invention can be soluble, e.g., cytosolic soluble, can be anchored to a biological membrane or can be organelle targeted or apoplastic targeted. The present invention also provides nucleic acid molecules encoding the metabolic regulators, methods of making the nucleic acid molecules, methods for making transformed organisms, including plants, photosynthetic organisms, microbes, invertebrates, and vertebrates, and methods for controlling availability of metabolites to a host cell.

Abstract: A method to generate siRNAs in vivo is described, as are constructs and compositions useful in the method. The method does not depend on the use of DNA or synthetic constructs that contain inverted duplications or dual promoters so as to form perfect or largely double-stranded RNA. Rather, the method depends on constructs that yield single-stranded RNA transcripts, and exploits endogenous or in vivo-produced miRNAs or siRNAs to initiate production of siRNAs. The miRNAs or siRNAs guide cleavage of the transcript and set the register for production of siRNAs (usually 21 nucleotides in length) encoded adjacent to the initiation cleavage site within the construct. The method results in specific formation of siRNAs of predictable size and register (phase) relative to the initiation cleavage site. The method can be used to produce specific siRNAs in vivo for inactivation or suppression of one or more target genes or other entities, such as pathogens.

Abstract: The invention provides methods and compositions useful in target sequence suppression and target sequence validation. The invention provides polynucleotide constructs useful for gene silencing, as well as cells, plants and seeds comprising the polynucleotides. The invention also provides a method for using microRNA to silence a target sequence.

Abstract: The present invention provides transgenic plants transformed with exogenous nucleic acid encoding a Dunaliella plasma membrane (PM)-ATPase. The transgenic plant has increased tolerance to salt as compared to a corresponding non-transgenic plant. The present invention also provides nucleic acids encoding a chimeric PM-ATPase, which comprise a first portion encoding a plant PM-ATPase or a fragment thereof, and a second portion encoding a Dunaliella PM-ATPase or a fragment thereof. The present invention also discloses a method of producing a transgenic plant having an increased tolerance to salt as compared to a corresponding non-transgenic plant, a method of modifying a plant capacity to survive salt shock, and a method of modifying plant recovery after exposure to salt stress, by introducing into one or more cells of a plant an exogenous nucleic acid encoding a Dunaliella PM-ATPase.

Abstract: This invention relates generally to a plant cell with enhanced nitrogen use efficiency and/or increased biomass production as compared to a corresponding non-transformed wild type plant cell by increasing or generating one or more activities of polypeptides associated with enhanced nitrogen use efficiency in plants.

Abstract: Provided are isolated polypeptides having glucoamylase activity, catalytic domains, and polynucleotides encoding the polypeptides, catalytic domains. Also provided are nucleic acid constructs, vectors and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides, catalytic domains.

Abstract: The present disclosure relates, in some embodiments, to compositions, organisms, systems, and methods for expressing a gene product in a plant using a expression control sequence (ECS) operable in monocots and/or dicots. For example, (i) an isolated nucleic acid may comprise an ECS (e.g., a sugarcane bacilliform virus promoter) and, optionally, an exogenous nucleic acid (ExNA) operably linked to the ECS; (ii) an expression vector may comprise an ECS; an ExNA; and, optionally, a 3? termination sequence, wherein the ECS has promoter activity sufficient to express the ExNA in at least one monocot and at least one dicot; (iii) a microorganism, plant cell, or plant may comprise an isolated nucleic acid; (iv) a method for constitutively expressing an ExNA in a plant (e.g.

Abstract: The present invention relates to amino acid sequences that are directed against RANK-L, as well as to compounds or constructs, and in particular proteins and polypeptides, that comprise or essentially consist of one or more such amino acid sequences. The invention also relates to nucleic acids encoding such amino acid sequences and polypeptides; to methods for preparing such amino acid sequences and polypeptides; to host cells expressing or capable of expressing such amino acid sequences or polypeptides; to compositions, and in particular to pharmaceutical compositions, that comprise such amino acid sequences, polypeptides, nucleic acids and/or host cells; and to uses of such amino acid sequences or polypeptides, nucleic acids, host cells and/or compositions, in particular for prophylactic, therapeutic or diagnostic purposes.

Abstract: The present disclosure provides tobacco inbred plants K326 SRC, CMS K326 SRC, K346 SRC, CMS K346 SRC, NC1562-1 SRC, NCTG-61 SRC, CMS NCTG-61 SRC and hybrid NC196 SRC. The present disclosure also provides parts of such plants and products made from those parts. The present disclosure also includes progeny of the provided plants including hybrids.

Abstract: The present invention provides a method of artificially repressing gene expression, which is simpler to design than conventional methods (the RNAi, ribozyme and antisense methods) and which allows for easier confirmation of the effect. A method of inhibiting the translation reaction of a target gene, comprising cutting out a part of the poly(A) tail and/or 3?-terminal sequence of the target mRNA is provided.

Abstract: Materials and methods for in vivo de-glycosylation of recombinant N-glycosylated proteins by co-expression with bacterial PNGase F (Peptide: N-glycosidase F) in plants, using a transient expression system are described. Methods are described which, for example, produce recombinant proteins of interest in plants in a non-glycosylated form. A method of expressing active bacterial PNGase F in plants also is provided.

Abstract: Compositions and methods for modifying the production levels of alkaloids in plants are provided. Alkaloid production can be genetically controlled by modulating the transcriptional activation of PMT genes mediated by members of the ERF family and/or Myc family of transcription factors. Novel nucleotide sequences encoding the Myc family of transcription factors are also provided.

Abstract: The present invention provides, as an enzyme which can be used for enzyme replacement therapy for Fabry disease, a protein having ?-galactosidase activity, which shows no allergic adverse side effect, shows a high stability in blood, and can be easily incorporated into a cell of an affected organ. The protein of the present invention is a protein which has acquired ?-galactosidase activity by changing the structure of the active site of wild-type human ?-N-acetylgalactosaminidase.

Abstract: The present invention refers to method for producing a transgenic plant with increased herbicide tolerance or resistance as compared to a corresponding non-transformed wild type plant, comprising transforming a plant cell or a plant cell nucleus or a plant tissue with a nucleic acid molecule encoding an Alopecurus cytochrome P450 monooxygenase, as well as to the nucleic acid, and plants with increased herbicide tolerance or resistance comprising the nucleic acid of the invention.

Abstract: The present disclosure provides for and relates to novel fusion proteins and polypeptides expressed by breast cancer and other cancer cells, and to compositions, materials and methods for detecting, characterizing and treating said breast and other cancers. In one embodiment, the fusion polypeptides are read-through fusion transcripts.

Abstract: The present invention concerns polypeptides comprising a variant Fc region. More particularly, the present invention concerns Fc region-containing polypeptides that have altered effector function as a consequence of one or more amino acid modifications in the Fc region thereof.

Abstract: The invention provides methods for making a target protein in a plant cell, and compositions thereof, wherein the target protein is a recombinant viral glycoprotein.

Abstract: The present disclosure relates, in some embodiments, to compositions, organisms, systems, and methods for expressing a gene product in a plant using a expression control sequence (ECS) operable in monocots and/or dicots. For example, (i) an isolated nucleic acid may comprise an ECS (e.g., a sugarcane bacilliform virus promoter) and, optionally, an exogenous nucleic acid (ExNA) operably linked to the ECS; (ii) an expression vector may comprise an ECS; an ExNA; and, optionally, a 3? termination sequence, wherein the ECS has promoter activity sufficient to express the ExNA in at least one monocot and at least one dicot; (iii) a microorganism, plant cell, or plant may comprise an isolated nucleic acid; (iv) a method for constitutively expressing an ExNA in a plant (e.g.

Abstract: By replacing the antigen-binding domain, the present inventors discovered novel polypeptide complexes that retain BiTE's strong anti-tumor activity and excellent safety properties, as well as have long half-life in blood and can damage various different target cells.

Abstract: A novel soybean variety, designated XB10A12 is provided. Also provided are the seeds of soybean variety XB10A12, cells from soybean variety XB10A12, plants of soybean XB10A12, and plant parts of soybean variety XB10A12. Methods provided include producing a soybean plant by crossing soybean variety XB10A12 with another soybean plant, methods for introgressing a transgenic trait, a mutant trait, and/or a native trait into soybean variety XB10A12, methods for producing other soybean varieties or plant parts derived from soybean variety XB10A12, and methods of characterizing soybean variety XB10A12. Soybean seed, cells, plants, germplasm, breeding lines, varieties, and plant parts produced by these methods and/or derived from soybean variety XB10A12 are further provided.

Abstract: A novel soybean variety, designated XB44E12 is provided. Also provided are the seeds of soybean variety XB44E12, cells from soybean variety XB44E12, plants of soybean XB44E12, and plant parts of soybean variety XB44E12. Methods provided include producing a soybean plant by crossing soybean variety XB44E12 with another soybean plant, methods for introgressing a transgenic trait, a mutant trait, and/or a native trait into soybean variety XB44E12, methods for producing other soybean varieties or plant parts derived from soybean variety XB44E12, and methods of characterizing soybean variety XB44E12. Soybean seed, cells, plants, germplasm, breeding lines, varieties, and plant parts produced by these methods and/or derived from soybean variety XB44E12 are further provided.

Abstract: A novel soybean variety, designated XB43J12 is provided. Also provided are the seeds of soybean variety XB43J12, cells from soybean variety XB43J12, plants of soybean XB43J12, and plant parts of soybean variety XB43J12. Methods provided include producing a soybean plant by crossing soybean variety XB43J12 with another soybean plant, methods for introgressing a transgenic trait, a mutant trait, and/or a native trait into soybean variety XB43J12, methods for producing other soybean varieties or plant parts derived from soybean variety XB43J12, and methods of characterizing soybean variety XB43J12. Soybean seed, cells, plants, germplasm, breeding lines, varieties, and plant parts produced by these methods and/or derived from soybean variety XB43J12 are further provided.

Abstract: A novel soybean variety, designated XBP18005 is provided. Also provided are the seeds of soybean variety XBP18005, cells from soybean variety XBP18005, plants of soybean XBP18005, and plant parts of soybean variety XBP18005. Methods provided include producing a soybean plant by crossing soybean variety XBP18005 with another soybean plant, methods for introgressing a transgenic trait, a mutant trait, and/or a native trait into soybean variety XBP18005, methods for producing other soybean varieties or plant parts derived from soybean variety XBP18005, and methods of characterizing soybean variety XBP18005. Soybean seed, cells, plants, germplasm, breeding lines, varieties, and plant parts produced by these methods and/or derived from soybean variety XBP18005 are further provided.

Abstract: A novel soybean variety, designated XB45E12 is provided. Also provided are the seeds of soybean variety XB45E12, cells from soybean variety XB45E12, plants of soybean XB45E12, and plant parts of soybean variety XB45E12. Methods provided include producing a soybean plant by crossing soybean variety XB45E12 with another soybean plant, methods for introgressing a transgenic trait, a mutant trait, and/or a native trait into soybean variety XB45E12, methods for producing other soybean varieties or plant parts derived from soybean variety XB45E12, and methods of characterizing soybean variety XB45E12. Soybean seed, cells, plants, germplasm, breeding lines, varieties, and plant parts produced by these methods and/or derived from soybean variety XB45E12 are further provided.

Abstract: A novel soybean variety, designated XB38AR12 is provided. Also provided are the seeds of soybean variety XB38AR12, cells from soybean variety XB38AR12, plants of soybean XB38AR12, and plant parts of soybean variety XB38AR12. Methods provided include producing a soybean plant by crossing soybean variety XB38AR12 with another soybean plant, methods for introgressing a transgenic trait, a mutant trait, and/or a native trait into soybean variety XB38AR12, methods for producing other soybean varieties or plant parts derived from soybean variety XB38AR12, and methods of characterizing soybean variety XB38AR12. Soybean seed, cells, plants, germplasm, breeding lines, varieties, and plant parts produced by these methods and/or derived from soybean variety XB38AR12 are further provided.

Abstract: A novel soybean variety, designated XB45J12 is provided. Also provided are the seeds of soybean variety XB45J12, cells from soybean variety XB45J12, plants of soybean XB45J12, and plant parts of soybean variety XB45J12. Methods provided include producing a soybean plant by crossing soybean variety XB45J12 with another soybean plant, methods for introgressing a transgenic trait, a mutant trait, and/or a native trait into soybean variety XB45J12, methods for producing other soybean varieties or plant parts derived from soybean variety XB45J12, and methods of characterizing soybean variety XB45J12. Soybean seed, cells, plants, germplasm, breeding lines, varieties, and plant parts produced by these methods and/or derived from soybean variety XB45J12 are further provided.

Abstract: A novel soybean variety, designated XBP14002 is provided. Also provided are the seeds of soybean variety XBP14002, cells from soybean variety XBP14002, plants of soybean XBP14002, and plant parts of soybean variety XBP14002. Methods provided include producing a soybean plant by crossing soybean variety XBP14002 with another soybean plant, methods for introgressing a transgenic trait, a mutant trait, and/or a native trait into soybean variety XBP14002, methods for producing other soybean varieties or plant parts derived from soybean variety XBP14002, and methods of characterizing soybean variety XBP14002. Soybean seed, cells, plants, germplasm, breeding lines, varieties, and plant parts produced by these methods and/or derived from soybean variety XBP14002 are further provided.

Abstract: Described herein are methods useful for producing proteins, such as enzymes, by agrofiltration. The methods involve producing an Agrobacterium with a Ti plasmid encoding a cellulase, infecting plant cells with the Agrobacterium, allowing expression of the cellulase, and recovering the cellulase from the plant cells. In one embodiment, the protein produced is an endoglucanase.

Abstract: Compositions and methods for modulating male fertility in a plant are provided. Compositions comprise nucleotide sequences, and active fragments and variants thereof, which modulate male fertility. Further provided are expression cassettes comprising the male fertility polynucleotides, or active fragments or variants thereof, operably linked to a promoter, wherein expression of the polynucleotides modulates the male fertility of a plant. Various methods are provided wherein the level and/or activity of the sequences that influence male fertility is modulated in a plant or plant part.

Abstract: The present invention relates to a valencene synthase, to a nucleic acid encoding such valencene synthase, to a host cell comprising said encoding nucleic acid sequence and to a method for preparing valencene, comprising converting farnesyl diphosphate to valencene in the presence of a valencene synthase according to the invention.

Abstract: A novel soybean variety, designated XB47R12 is provided. Also provided are the seeds of soybean variety XB47R12, cells from soybean variety XB47R12, plants of soybean XB47R12, and plant parts of soybean variety XB47R12. Methods provided include producing a soybean plant by crossing soybean variety XB47R12 with another soybean plant, methods for introgressing a transgenic trait, a mutant trait, and/or a native trait into soybean variety XB47R12, methods for producing other soybean varieties or plant parts derived from soybean variety XB47R12, and methods of characterizing soybean variety XB47R12. Soybean seed, cells, plants, germplasm, breeding lines, varieties, and plant parts produced by these methods and/or derived from soybean variety XB47R12 are further provided.

Abstract: A novel soybean variety, designated XB45K12 is provided. Also provided are the seeds of soybean variety XB45K12, cells from soybean variety XB45K12, plants of soybean XB45K12, and plant parts of soybean variety XB45K12. Methods provided include producing a soybean plant by crossing soybean variety XB45K12 with another soybean plant, methods for introgressing a transgenic trait, a mutant trait, and/or a native trait into soybean variety XB45K12, methods for producing other soybean varieties or plant parts derived from soybean variety XB45K12, and methods of characterizing soybean variety XB45K12. Soybean seed, cells, plants, germplasm, breeding lines, varieties, and plant parts produced by these methods and/or derived from soybean variety XB45K12 are further provided.

Abstract: The present invention discloses regulatory sequences, promoters and terminators, and their use in plants. The regulatory sequences can be used to make gene constructs that include a gene not natively associated with the regulatory sequences. Methods to use the regulatory sequences with antisense constructs or functional RNAs are disclosed. Methods to use the regulatory sequences, promoter or terminator, independently of each other are also disclosed. Methods to use the regulatory sequences to improve plant growth and production such as increased biomass, increased yield and increased tolerance to abiotic or biotic stresses are also disclosed.

Abstract: A novel soybean variety, designated XB05Y12 is provided. Also provided are the seeds of soybean variety XB05Y12, cells from soybean variety XB05Y12, plants of soybean XB05Y12, and plant parts of soybean variety XB05Y12. Methods provided include producing a soybean plant by crossing soybean variety XB05Y12 with another soybean plant, methods for introgressing a transgenic trait, a mutant trait, and/or a native trait into soybean variety XB05Y12, methods for producing other soybean varieties or plant parts derived from soybean variety XB05Y12, and methods of characterizing soybean variety XB05Y12. Soybean seed, cells, plants, germplasm, breeding lines, varieties, and plant parts produced by these methods and/or derived from soybean variety XB05Y12 are further provided.

Abstract: The present invention describes the plant-based production of a therapeutic antibody against West Nile Virus.

Abstract: Compositions and methods for conferring hydroxyphenyl pyruvate dioxygenase (HPPD) herbicide resistance or tolerance to plants are provided. Compositions include amino acid sequences, and variants and fragments thereof, for mutant HPPD polypeptides. Nucleic acids that encode the mutant HPPD polypeptides are also provided. Methods for conferring herbicide resistance or tolerance, particularly resistance or tolerance to certain classes of herbicides that inhibit HPPD, in plants are further provided. Methods are also provided for selectively controlling weeds in a field at a crop locus and for the assay, characterization, identification and selection of the mutant HPPDs of the current invention that provide herbicide tolerance.

Abstract: The present invention provides a pharmaceutical composition comprising a protein having ?-galactosidase activity for treating Fabry disease, which causes no allergic side effect, which is highly stable in blood (plasma) and which can readily be taken up by a cell of an affected organ. The pharmaceutical composition for treating Fabry disease of the invention comprises, for example, a protein which acquires an ?-galactosidase activity through alteration of the structure of the active site of wild-type human ?-N-acetylgalactosaminidase.

Abstract: The invention provides a comprehensive, rapid, unbiased, and accurate method for identifying and/or discovering disease-associated genetic variations, e.g., disease-associated variations. The present invention further provides novel disease-associated genetic variations for use as genetic markers of disease, e.g., cancer. The invention further provides methods for assessing an individual's risk for developing a disease, e.g., cancer, by detecting the presence the novel disease-associated genetic variations of the invention.

Abstract: A novel soybean variety, designated XR33AQ12 is provided. Also provided are the seeds of soybean variety XR33AQ12, cells from soybean variety XR33AQ12, plants of soybean XR33AQ12, and plant parts of soybean variety XR33AQ12. Methods provided include producing a soybean plant by crossing soybean variety XR33AQ12 with another soybean plant, methods for introgressing a transgenic trait, a mutant trait, and/or a native trait into soybean variety XR33AQ12, methods for producing other soybean varieties or plant parts derived from soybean variety XR33AQ12, and methods of characterizing soybean variety XR33AQ12. Soybean seed, cells, plants, germplasm, breeding lines, varieties, and plant parts produced by these methods and/or derived from soybean variety XR33AQ12 are further provided.

Abstract: A novel soybean variety, designated XBP05003 is provided. Also provided are the seeds of soybean variety XBP05003, cells from soybean variety XBP05003, plants of soybean XBP05003, and plant parts of soybean variety XBP05003. Methods provided include producing a soybean plant by crossing soybean variety XBP05003 with another soybean plant, methods for introgressing a transgenic trait, a mutant trait, and/or a native trait into soybean variety XBP05003, methods for producing other soybean varieties or plant parts derived from soybean variety XBP05003, and methods of characterizing soybean variety XBP05003. Soybean seed, cells, plants, germplasm, breeding lines, varieties, and plant parts produced by these methods and/or derived from soybean variety XBP05003 are further provided.

Abstract: A novel soybean variety, designated XB47T12 is provided. Also provided are the seeds of soybean variety XB47T12, cells from soybean variety XB47T12, plants of soybean XB47T12, and plant parts of soybean variety XB47T12. Methods provided include producing a soybean plant by crossing soybean variety XB47T12 with another soybean plant, methods for introgressing a transgenic trait, a mutant trait, and/or a native trait into soybean variety XB47T12, methods for producing other soybean varieties or plant parts derived from soybean variety XB47T12, and methods of characterizing soybean variety XB47T12. Soybean seed, cells, plants, germplasm, breeding lines, varieties, and plant parts produced by these methods and/or derived from soybean variety XB47T12 are further provided.

Abstract: A novel soybean variety, designated XB47U12 is provided. Also provided are the seeds of soybean variety XB47U12, cells from soybean variety XB47U12, plants of soybean XB47U12, and plant parts of soybean variety XB47U12. Methods provided include producing a soybean plant by crossing soybean variety XB47U12 with another soybean plant, methods for introgressing a transgenic trait, a mutant trait, and/or a native trait into soybean variety XB47U12, methods for producing other soybean varieties or plant parts derived from soybean variety XB47U12, and methods of characterizing soybean variety XB47U12. Soybean seed, cells, plants, germplasm, breeding lines, varieties, and plant parts produced by these methods and/or derived from soybean variety XB47U12 are further provided.

Abstract: A novel soybean variety, designated XB49K12 is provided. Also provided are the seeds of soybean variety XB49K12, cells from soybean variety XB49K12, plants of soybean XB49K12, and plant parts of soybean variety XB49K12. Methods provided include producing a soybean plant by crossing soybean variety XB49K12 with another soybean plant, methods for introgressing a transgenic trait, a mutant trait, and/or a native trait into soybean variety XB49K12, methods for producing other soybean varieties or plant parts derived from soybean variety XB49K12, and methods of characterizing soybean variety XB49K12. Soybean seed, cells, plants, germplasm, breeding lines, varieties, and plant parts produced by these methods and/or derived from soybean variety XB49K12 are further provided.

Abstract: The invention relates to genetically modified agricultural plants with increased oil content in vegetative tissues, as well as to expression systems, plant cells, seeds and vegetative tissues related thereto.

Abstract: Plant metabolism and alkaloid levels can be regulated by transcription factors that regulate the nicotinic alkaloid biosynthetic pathway.

Abstract: A novel soybean variety, designated XB48E12 is provided. Also provided are the seeds of soybean variety XB48E12, cells from soybean variety XB48E12, plants of soybean XB48E12, and plant parts of soybean variety XB48E12. Methods provided include producing a soybean plant by crossing soybean variety XB48E12 with another soybean plant, methods for introgressing a transgenic trait, a mutant trait, and/or a native trait into soybean variety XB48E12, methods for producing other soybean varieties or plant parts derived from soybean variety XB48E12, and methods of characterizing soybean variety XB48E12. Soybean seed, cells, plants, germplasm, breeding lines, varieties, and plant parts produced by these methods and/or derived from soybean variety XB48E12 are further provided.

Abstract: A novel soybean variety, designated XB00R12 is provided. Also provided are the seeds of soybean variety XB00R12, cells from soybean variety XB00R12, plants of soybean XB00R12, and plant parts of soybean variety XB00R12. Methods provided include producing a soybean plant by crossing soybean variety XB00R12 with another soybean plant, methods for introgressing a transgenic trait, a mutant trait, and/or a native trait into soybean variety XB00R12, methods for producing other soybean varieties or plant parts derived from soybean variety XB00R12, and methods of characterizing soybean variety XB00R12. Soybean seed, cells, plants, germplasm, breeding lines, varieties, and plant parts produced by these methods and/or derived from soybean variety XB00R12 are further provided.