Formaldehyde Or Acetone Patents (Class 436/130)
  • Patent number: 10294252
    Abstract: The present disclosure provides a new series of compounds exhibiting high fluorescence quantum yields in the solid state. In one embodiment, the compounds include a series of 2,3,4,5-tetraphenylgermoles with the same or different 1,1-substituents. In another embodiment, substituted germafluorenes, germa-fluoresceins/rhodamines, and germapins are described. These germanium heterocycles possess ideal photophysical and thermostability properties, which makes them excellent candidates for chemical or biological sensors, host materials for electroluminescent devices and solar cells, and emissive and for electron-transport layer components in organic light emitting diode devices.
    Type: Grant
    Filed: June 11, 2013
    Date of Patent: May 21, 2019
    Assignee: The Curators of the University of Missouri
    Inventors: Janet Braddock-Wilking, Teresa Lynn Bandrowsky, James Bryan Carroll, II
  • Patent number: 10241076
    Abstract: In a method for identifying an explosive in a sample, an explosive fingerprint defined by a set of kinetic parameters is received. The kinetic parameters describe a plurality of interactions between the explosive and each of a respective plurality of functional moieties. A data processor is used for accessing a database of explosive fingerprints, and searching the database for a database fingerprint matching the received fingerprint.
    Type: Grant
    Filed: January 20, 2014
    Date of Patent: March 26, 2019
    Assignee: Tracense System Ltd.
    Inventors: Fernando Patolsky, Ronen Shacham, Amir Lichtenstein, Ehud Havivi, Ehud Hahamy
  • Patent number: 10241078
    Abstract: Functionalized nanotube arrays, sensors, and related methods of detecting target compounds are presented. A functionalized nanotube array (235) can include a plurality of metal oxide nanotubes (240). The metal oxide nanotubes (240) can be formed of a metal oxide and can have an interior or exterior surface that is optionally functionalized with at least one metal ion. These metal nanotubes (240) can be used in a sensor (200) for detecting target compounds such as volatile organic compounds, and biomarkers in a fluid environment. The sensor (200) can further include a power source (245) configured to apply a voltage to the nanotube array (235) and a current sensor (250) configured to monitor and detect changes in a response current which varies upon binding with the target compounds.
    Type: Grant
    Filed: October 29, 2013
    Date of Patent: March 26, 2019
    Assignee: University of Utah Research Foundation
    Inventors: Swomitra Kumar Mohanty, Manoranjan Misra, Younghwan Kim, Jules Magda
  • Patent number: 9797849
    Abstract: A process combustion transmitter is provided. The transmitter includes a process probe extendible into a flow of process combustion exhaust. The process probe has a measurement cell with an operating temperature that is above a flashpoint of process combustion fuel. The process probe includes a heater configured to heat the measurement cell to the operating temperature. Electronic circuitry is coupled to the measurement cell and to the heater. The electronic circuitry is configured to disengage power to the heater once process combustion heat is sufficient to maintain the measurement cell at the operating temperature and thereafter to maintain the heater in a de-energized state.
    Type: Grant
    Filed: March 21, 2014
    Date of Patent: October 24, 2017
    Assignee: Rosemount Analytical Inc.
    Inventors: James D. Kramer, Joseph C. Nemer, Douglas E. Simmers
  • Patent number: 9772287
    Abstract: An analytical system and method for periodically monitoring an injection water distribution pipeline for the presence and concentration of formaldehyde or other aldehyde-functional biocide includes pumps, one of which provides a predetermined volume of injection water drawn from the pipeline at a sampling point and the other a predetermined volume of a reagent, preferably a buffered solution of dimedone, from a reagent storage vessel which are mixed and then heated in a chamber to a predetermined temperature to promote formation of any reaction products. The heated reaction mixture is passed to a detection cell and exposed to light of predetermined wavelength which, in accordance with the Hantzsch reaction, molecules having an aldehyde functional group that reacted with dimedone produce a fluorescence-emitting reaction product, the intensity of which is measured and compared to data previously obtained from standard aldehyde-containing solutions.
    Type: Grant
    Filed: April 16, 2014
    Date of Patent: September 26, 2017
    Assignee: Saudi Arabian Oil Company
    Inventors: Mohammed A. Al-Moniee, Naim Akmal, Peter Frank Sanders, Fahad N. Al-Abeedi
  • Patent number: 9518991
    Abstract: Methods and devices are provided for analyzing acetone in breath. One such method comprises disposing a reactant in a reaction zone within the breath analysis device, wherein the reactant comprises a primary amine disposed on a surface, and wherein the reaction zone has an optical characteristic that is at a reference level. It also comprises pre-storing a liquid nitroprusside solution within the breath analysis device separately from the reactant. The method further comprises using the breath analysis device to cause the breath to contact the reactant in the reaction zone so that the acetone in the breath reacts with the reactant to form a reaction product and, after the reaction product has been formed, using the breath analysis device to cause the nitroprusside solution to contact and react with the reaction product and to facilitate a change in the optical characteristic of the reaction zone relative to the reference level.
    Type: Grant
    Filed: May 15, 2013
    Date of Patent: December 13, 2016
    Assignee: Invoy Technologies, LLC
    Inventors: Lubna M. Ahmad, Brent Satterfield, Rhett Martineau
  • Patent number: 9470675
    Abstract: The present invention provides a composition for acetone detection and a process of preparation thereof. The composition comprises ?-ferric oxide (?-Fe2O3), antimony (Sb) salt, and platinum (Pt). The sensor fabricated using the said composition is selective to low concentration of breath acetone, the biomarker of diabetes, in presence of high amount of moisture normally present in breath. Such semiconductor sensors for diabetes monitoring are inexpensive, rugged, patient-friendly and on the top, non-invasive.
    Type: Grant
    Filed: March 4, 2013
    Date of Patent: October 18, 2016
    Assignee: COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH
    Inventors: Amarnath Sen, Subhasis Rana
  • Patent number: 9459151
    Abstract: A gas measurement system for measuring the concentration of gaseous and/or vaporous components of a gas mixture by means of a color change of at least one reaction substance on a reaction support unit, which is arranged in at least two light permeable channels in such a manner that the color change on the reaction substance can be detected at low expense on a large number of separate positions. The detecting unit which detects the color change can be designed as a digital camera with an electronic image converter or image sensor, and an imaging optics system (e.g., a lens system). Related systems, methods, apparatus, and articles are also described.
    Type: Grant
    Filed: July 17, 2013
    Date of Patent: October 4, 2016
    Assignee: DRÄGER SAFETY AG & CO. KGaA
    Inventors: Hans-Ullrich Hansmann, Andreas Mohrmann, Arne Tröllsch, Rainer Polzius
  • Patent number: 9207223
    Abstract: A calibration device for a breath alcohol testing device includes a pump providing a controlled air flow at a predetermined rate, a chamber in fluid communication with the pump that receives the air flow from the pump, and an outlet opening in fluid communication with the chamber that allows the air flow to exit the chamber in which the chamber and/or outlet opening can be heated to a predetermined maintainable temperature during operation of the pump. The calibration device is releasably connected to or brought in fluid communication with a breath alcohol testing device such that the air flow exiting the outlet opening passes into the testing device. The calibration device receives a sealed cartridge containing a predetermined alcohol concentration in the chamber and further includes a lid for opening/closing the chamber wherein the cartridge can be pierced such that the air flow provided by the pump to the chamber will pass through the cartridge.
    Type: Grant
    Filed: June 27, 2013
    Date of Patent: December 8, 2015
    Assignee: Alco Systems Sweden AB
    Inventors: Miguel Arias, Nigel Evans
  • Publication number: 20150132858
    Abstract: Methods and devices are provided for analyzing acetone in breath. One such method comprises disposing a reactant in a reaction zone within the breath analysis device, wherein the reactant comprises a primary amine disposed on a surface, and wherein the reaction zone has an optical characteristic that is at a reference level. It also comprises pre-storing a liquid nitroprusside solution within the breath analysis device separately from the reactant. The method further comprises using the breath analysis device to cause the breath to contact the reactant in the reaction zone so that the acetone in the breath reacts with the reactant to form a reaction product and, after the reaction product has been formed, using the breath analysis device to cause the nitroprusside solution to contact and react with the reaction product and to facilitate a change in the optical characteristic of the reaction zone relative to the reference level.
    Type: Application
    Filed: May 15, 2013
    Publication date: May 14, 2015
    Inventors: Lubna M. Ahmad, Brent Satterfield, Rhett Martineau
  • Publication number: 20150132857
    Abstract: A device for detecting airborne contaminants includes a protonated, electrically conductive sensing material with affinity for binding with, and capable of being deprotonated by, the airborne contaminant. Electronics measure a property of the sensing material that is sensitive to deprotonation and generates signals indicative of the airborne contaminant. A method for detecting airborne contaminants includes: determining a property change of the protonated, electrically conductive material; and determining presence of the airborne contaminant based on the change.
    Type: Application
    Filed: June 13, 2013
    Publication date: May 14, 2015
    Inventors: Joseph J. Belbruno, Susanne E. Tanski
  • Patent number: 8980640
    Abstract: The present invention relates to gas sensors using doped ferroelectric materials. The sensors can be fabricated as an array where different portions of the array can operate at different independently controlled temperatures to detect different gas phase components of a gas sample. Preferred embodiments can be used for the diagnosis of conditions, such as, diabetes.
    Type: Grant
    Filed: December 2, 2010
    Date of Patent: March 17, 2015
    Assignee: The Research Foundation of State University of New York
    Inventor: Pelagia-Irene Gouma
  • Publication number: 20150065365
    Abstract: An apparatus is provided for sensing an analyte in a fluid.
    Type: Application
    Filed: May 12, 2014
    Publication date: March 5, 2015
    Applicant: Invoy Technologies, L.L.C
    Inventor: Lubna Ahmad
  • Publication number: 20150031582
    Abstract: A method comprising (a) obtaining one or more biological samples from a subject wherein the subject has undergone an organ transplant; (b) determining the amount and type of one or more volatile organic compounds in the biological sample; and (c) correlating the amount of volatile organic compounds to a degree of transplant rejection. A device comprising a plurality of sensors configured to detect a plurality of volatile organic compounds in a biological sample of a subject having undergone an organ transplant.
    Type: Application
    Filed: July 28, 2014
    Publication date: January 29, 2015
    Applicant: UNIVERSITY OF HOUSTON SYSTEM
    Inventors: Dong Cai, Zhifeng Ren, Xian C. Li, Renard L. Thomas
  • Publication number: 20140234977
    Abstract: Field-effect transistors include at least two thin layers of a semiconductor material and of an electrically conductive gate material that are rolled up together. These two layers are arranged separated from one another by one or multiple barrier layers and this rolled-up multi-layer structure is integratable as field-effect transistors in circuits and/or in microfluid systems as sensors for the detection of fluids.
    Type: Application
    Filed: December 2, 2013
    Publication date: August 21, 2014
    Applicant: LEIBNIZ-INSTITUT FUER FESTKOERPER-UND WERKSTOFFFORSCHUNG DRESDEN E.V
    Inventors: Daniel GRIMM, Oliver G. SCHMIDT, Carlos Cesar Bof BUFON
  • Publication number: 20140227795
    Abstract: This disclosure relates to the field of molecularly imprinted polymers for detecting target molecules.
    Type: Application
    Filed: August 30, 2012
    Publication date: August 14, 2014
    Applicant: THE TRUSTEES OF DARTMOUTH COLLEGE
    Inventor: Joseph J. Belbruno
  • Patent number: 8759111
    Abstract: Porous sol-gel material essentially consisting of units of one or more first polyalkoxysilanes chosen from the following compounds: (chloromethyl)triethoxysilane; 1,3-dimethyltetramethoxydisiloxane; ethyl trimethoxysilane; triethoxy(ethyl)silane; triethoxymethylsilane; triethoxy(vinyl)silane; trimethoxymethylsilane; trimethoxy(vinyl)silane; tetraethoxysilane or tetramethoxysilane (TMOS) and of units of one or more second polyalkoxysilanes chosen from the following compounds: (N-(3-(trimethoxysilyl)propyl)ethylenediamine; 3-aminopropyltriethoxysilane (APTES) and 3-aminopropyltrimethoxysilane, in a first polyalkoxysilane/second polyalkoxysilane molar ratio of 1/0.01 to 1/1, optionally comprising a probe molecule, method of preparation and applications in the trapping of monocyclic aromatic hydrocarbons and other pollutants or in their detection.
    Type: Grant
    Filed: July 10, 2009
    Date of Patent: June 24, 2014
    Assignees: CEA—Commisariat a l'Energie Atomique et aux Energies Alternatives, CNRS—Centre National de la Recherche Scientifique
    Inventors: Sabine Crunaire, Thu-Hoa Tran-Thi
  • Publication number: 20140147926
    Abstract: This invention relates to a method of analyzing an aldehyde compound in a metal plating solution, including adding a pH control solution to an aldehyde derivative, thus preparing an oversaturated aldehyde derivative solution in which the aldehyde derivative is dissolved to be oversaturated while the pH of the aldehyde derivative solution is adjusted to be the same as that of the metal plating solution; adding the oversaturated aldehyde derivative solution to the metal plating solution, so that the aldehyde compound which is present in the metal plating solution undergoes derivation, thus obtaining an aldehyde derivative compound; extracting the aldehyde derivative compound; and analyzing the aldehyde compound from the extracted aldehyde derivative compound.
    Type: Application
    Filed: March 14, 2013
    Publication date: May 29, 2014
    Applicant: SAMSUNG ELECTRO-MECHANICS CO., LTD.
    Inventors: Ji Eun Jeon, Se Kyung Lee, Hyo Jin Yoon, Suk Jin Ham
  • Patent number: 8685739
    Abstract: There is provided a method of diagnosing a disease state in a subject. The disease state is caused or effected by pneumococcal infection. The method includes obtaining a biological test sample from the subject. The biological sample includes at least one metabolite selected from the group consisting of citrate, trigonelline, acetylcarnitine, acetone, myo-inositol, 3-hydroxybutyrate, glucose and carnitine. A respective concentration of each one of the at least one metabolite is compared with a predetermined concentration value associated with a corresponding one of the at least one metabolite. The predetermined concentration value is indicative of the disease state. For example, the biological sample includes any one of citrate, trigonelline, acetylcamitine, acetone, myoinositol, 3-hydroxybutyrate, glucose and carnitine. As a further example, the biological samples include any combination of citrate, trigonelline, acetylcamitine, acetone, myo-inositol, 3-hydroxybutyrate, glucose and carnitine.
    Type: Grant
    Filed: April 14, 2008
    Date of Patent: April 1, 2014
    Inventors: Carolyn Slupsky, Thomas Marrie
  • Patent number: 8586383
    Abstract: The invention relates to a device (10) for detection of harmful substances with a measurement unit (28) for measuring at least one harmful substance and an evaluation unit (30) for determining the concentration of the at least one harmful substance. The invention also relates to a method for detecting harmful substances in a gas mixture. It is hereby provided that the gas mixture is tested for a gaseous harmful substance or simultaneously for several gaseous harmful substances, wherein the gaseous harmful substance or the gaseous harmful substances is/are measured with different sensor means, and the gaseous harmful substances are optionally chemically modified such that a measurement is performed with the existing sensor means.
    Type: Grant
    Filed: May 13, 2011
    Date of Patent: November 19, 2013
    Assignee: Airsense Analytics
    Inventors: Andreas Walte, Wolf Münchmeyer
  • Publication number: 20130189791
    Abstract: Methods for measuring formaldehyde emissions from a plurality of samples. An electrochemical sensor can be calibrated using a reference sample to provide a calibrated electrochemical sensor, where the time of calibration is equal to time zero. A plurality of samples can be placed within a sample chamber one at a time and a formaldehyde concentration of a gas passed across one or more surfaces of each sample can be measured. The first sample measured can be measured again as the last sample. A linear regression trend-line based on the two formaldehyde concentrations measured from the first sample can be generated. A revised linear regression trend-line based on what the formaldehyde concentration of the first sample would be at time zero and the formaldehyde concentration of the first sample when re-measured as the last sample can be generated. A correction factor for at least one of the plurality of samples measured between the two measurements of the first sample can be generated.
    Type: Application
    Filed: January 18, 2013
    Publication date: July 25, 2013
    Applicant: GEORGIA-PACIFIC CHEMICALS LLC
    Inventor: Georgia-Pacific Chemicals LLC
  • Publication number: 20130115706
    Abstract: The present invention relates to gas sensors using doped ferroelectric materials. The sensors can be fabricated as an array where different portions of the array can operate at different independently controlled temperatures to detect different gas phase components of a gas sample. Preferred embodiments can be used for the diagnosis of conditions, such as, diabetes.
    Type: Application
    Filed: December 2, 2010
    Publication date: May 9, 2013
    Inventor: Pelagia-Irene Gouma
  • Patent number: 8415166
    Abstract: The present invention provides a device for the detection of a peroxide-based explosive, in particular, triacetone triperoxide (TATP), which is based on a molecular controlled semiconductor resistor (MOCSER) and composed of at least one insulating or semi-insulating layer, at least one conducting semiconductor layer, two conducting pads and a layer of multifunctional organic molecules capable of adsorbing molecules of the peroxide-based explosive. The invention further provides an array of semiconductor devices for the selective detection of a peroxide-based explosive, as well as a method for the selective detection of vapors of a peroxide-based explosive in a gaseous mixture using this array.
    Type: Grant
    Filed: May 12, 2009
    Date of Patent: April 9, 2013
    Assignee: Yeda Research and Development Co. Ltd.
    Inventors: Ron Naaman, Eyal Capua, Roberto Cao
  • Publication number: 20120308992
    Abstract: A method of preparing a dry stick test device for determining an analyte in a milk sample by chemical assay. At least one reagent pad is provided by impregnating a first porous material with an aqueous solution including a reagent capable of reacting with the analyte, a derivative of the analyte or an indicator compound for the analyte to provide a detectable signal when in a moistened state. The reagent pad is dried. A development pad is provided by impregnating a second porous material with an aqueous solution including at least one controlling compound which, when in a moistened state, is capable of providing a condition required for the reagent to react with the analyte to provide the detectable signal. The impregnated second porous material is dried. The first porous material is immobilized with the second porous material, on a solid support, to obtain the dry stick test device.
    Type: Application
    Filed: June 11, 2012
    Publication date: December 6, 2012
    Inventor: Lars NYGAARD
  • Publication number: 20120288951
    Abstract: The present invention relates to the field of detection of components in gas phase, and in particular to detection of nitric oxide exhaled as a component of breath, using a liquid crystal assay format and a device utilizing liquid crystals as part of a reporting system.
    Type: Application
    Filed: April 27, 2012
    Publication date: November 15, 2012
    Applicant: PLATYPUS TECHNOLOGIES, LLC
    Inventors: Bharat Acharya, Avijit Sen, Nicholas Abbott, Kurt Kupcho
  • Patent number: 8288163
    Abstract: The present invention relates to a device and process for the quick and reliable online detection of triacetone triperoxide (TATP).
    Type: Grant
    Filed: February 11, 2009
    Date of Patent: October 16, 2012
    Assignees: Rheinische Friedrich-Wilhelms-Universitaet Bonn, Max-Planck-Gesellschaft zur Foerderung der Wissenschaften E.V.
    Inventors: Siegfried R. Waldvogel, Jürgen Lörgen, Daniel Lubczyk, Klaus Müllen, Roland Bauer
  • Publication number: 20120149122
    Abstract: A device for determining the concentration of a compound in an aqueous phase in a dynamic manner and while flowing, and a device (300) for determining the concentration of a compound in a gaseous phase and soluble in an aqueous phase. The device (200, 300) for determining the concentration of a compound in a gaseous phase includes elements (302) for transferring the compounds present in the gaseous phase to an aqueous phase then determining in a dynamic manner and while flowing, the concentration of the compounds in this aqueous phase by fluorescence spectroscopy. The devices (300) are robust, conveyable and less costly, and have greater temporal as well as spatial sensitivity than the devices of the state of the art.
    Type: Application
    Filed: June 8, 2010
    Publication date: June 14, 2012
    Applicants: UNIVERSITE DE STRASBOURG, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Stéphane Cyrille Olivier Le Calve, Wuyin Zheng, Jean-Luc Nicolas Charles Ponche, Pierre Michel Bernhardt
  • Publication number: 20120083039
    Abstract: The invention relates to a method for quantitatively determining impurities in the form of aldehydes and ketones in glycerin serving for preparing pharmaceuticals, in which the glycerin containing impurities is reacted with a derivatization reagent in a sample solution and the quantity of derivatized impurities is determined. Said method is characterized in that PFBHA, O-(2,3,4,5,6-pentafluorobenzyl)-hydroxylamine hydrochloride, is used as the derivatization reagent, the derivatizing is conducted in the presence of a solubilizer in the form of a polar organic solvent, and liquid chromatographic separation and UV detection are performed. A subject matter of the invention is also the use of glycerin, in which the content of impurities of 9 ppm or less has been determined by means of the described method in a pharmaceutical preparation. According to the invention, impurities in glycerin can be better determined.
    Type: Application
    Filed: September 30, 2011
    Publication date: April 5, 2012
    Applicant: Aug. Hedinger GMBH & Co. KG
    Inventors: Frank MILEK, Rouven JOSL
  • Publication number: 20110300635
    Abstract: Articles and methods for the detection and/or quantification of organic analytes are described. The invention provides a chemical indicator test strip, comprising: a substrate; and a coating comprising a leuco dye complex on the substrate, the coating being insoluble in water and reactive with an organic analyte, the coating derived from a solution of leuco dye and developing agent. In another aspect, the coating further comprises adjuvant, in the form of a water-insoluble, polar, hydrophobic, aprotic material that extends the lower limit of detection for the analyte. In still another aspect, the present invention provides a method of using a chemical indicator test strip, comprising: (a) exposing the chemical indicator test strip to a sample comprising an organic analyte; (b) measuring a color change on the chemical indicator test strip following the exposing step; and (c) correlating the color change with the concentration of the analyte in the sample.
    Type: Application
    Filed: August 16, 2011
    Publication date: December 8, 2011
    Inventor: Vinod P. Menon
  • Publication number: 20110281367
    Abstract: The invention relates to a device (10) for detection of harmful substances with a measurement unit (28) for measuring at least one harmful substance and an evaluation unit (30) for determining the concentration of the at least one harmful substance. The invention also relates to a method for detecting harmful substances in a gas mixture. It is hereby provided that the gas mixture is tested for a gaseous harmful substance or simultaneously for several gaseous harmful substances, wherein the gaseous harmful substance or the gaseous harmful substances is/are measured with different sensor means, and the gaseous harmful substances are optionally chemically modified such that a measurement is performed with the existing sensor means.
    Type: Application
    Filed: May 13, 2011
    Publication date: November 17, 2011
    Applicant: Airsense Analytics GmbH
    Inventors: Andreas WALTE, Wolf MÜNCHMEYER
  • Patent number: 8012761
    Abstract: A method for rapidly detecting the presence of formaldehyde in a urine sample (e.g., urine or a urinary material associated therewith, such as headspace gas located associated with urine) is provided. The method includes contacting the urine sample with a substrate on which is disposed a colorant that is capable of undergoing a detectable color change in the presence of formaldehyde. Without intending to be limited by theory, it is believed that oxidation of the colorant by formaldehyde induces either a shift of the absorption maxima towards the red end of the spectrum (“bathochromic shift”) or towards the blue end of the spectrum (“hypsochromic shift”). The absorption shift provides a color difference that is detectable, either visually or through instrumentation, to indicate the presence of formaldehyde within the urine sample. For example, prior to contact with a urine sample, the colorant may be colorless or it may possess a certain color.
    Type: Grant
    Filed: December 14, 2006
    Date of Patent: September 6, 2011
    Assignee: Kimberly-Clark Worldwide, Inc.
    Inventors: Rameshbabu Boga, Stephanie M. Martin, Molly K. Smith, Kevin Peter McGrath
  • Publication number: 20110151573
    Abstract: Porous sol-gel material essentially consisting of units of one or more first polyalkoxysilanes chosen from the following compounds: (chloromethyl)triethoxysilane; 1,3-dimethyltetramethoxydisiloxane; ethyl trimethoxysilane; triethoxy(ethyl)silane; triethoxymethylsilane; triethoxy(vinyl)silane; trimethoxymethylsilane; trimethoxy(vinyl)silane; tetraethoxysilane or tetramethoxysilane (TMOS) and of units of one or more second polyalkoxysilanes chosen from the following compounds: (N-(3-(trimethoxysilyl)propyl)ethylenediamine; 3-aminopropyltriethoxysilane (APTES) and 3-aminopropyltrimethoxysilane, in a first polyalkoxysilane/second polyalkoxysilane molar ratio of 1/0.01 to 1/1, optionally comprising a probe molecule, method of preparation and applications in the trapping of monocyclic aromatic hydrocarbons and other pollutants or in their detection.
    Type: Application
    Filed: July 10, 2009
    Publication date: June 23, 2011
    Inventors: Sabine Crunaire, Thu-Hoa Tran-Thi
  • Patent number: 7820962
    Abstract: An ion mobility spectrometer has a drift chamber (1) with an inlet (2) at one end by which a gas or vapor being analyzed is supplied to the chamber. After ionization, molecules are admitted through a gate 8 and flow along a drift region (9) to a collector plate (11). A drift gas is flowed through the drift region against the flow of ionized molecules and is circulated along a flow path (31, 32, 40) and (30), which includes a chamber (50) including a dopant. The dopant is 2,4-pentanedione, which has been found to enhance the detection of a number of compounds especially toxic industrial chemicals and nitrogen compounds, such as those present in the breath of mammals.
    Type: Grant
    Filed: May 12, 2006
    Date of Patent: October 26, 2010
    Assignee: Smiths Detection - Watford Limited
    Inventors: Paul Grant Wynn, Henry Paul McIntyre
  • Patent number: 7799572
    Abstract: According to an aspect of the invention, a polymerized form of formaldehyde is available in granular form containing a polymerized form of formaldehyde, such as paraformaldehyde, a buffer, such as sodium phosphate dibasic anhydrous, and a stabilizer, such as hydroxymethyl cellulose, or hydroxypropyl methyl cellulose. When added to an aqueous solvent, the paraformaldehyde can dissolve in alkaline solution, and depolymerizes into a formaldehyde solution containing a stabilizer. Optionally a second member of the buffer pair or another buffer or pH adjuster can be used The stabilized depolymerized formaldehyde solution is then ready for use, or can be modified by addition of other substances, such as sodium phosphate monobasic monohydrate. Additionally, an additional buffer may be included in the granular mixture to increase the rate at which the solid dissolves and depolymerizes.
    Type: Grant
    Filed: February 28, 2007
    Date of Patent: September 21, 2010
    Inventor: James L Biesecker
  • Patent number: 7790467
    Abstract: An apparatus and method for quantifying ketone or alydehyde concentrations of gas. The invention includes passing a gas sample through a reactor and an optical cell and determining a concentration of a gaseous reaction product. Using the concentration of the gaseous reaction product and a predetermined reaction conversion efficiency, a ketone or aldehyde concentration is calculated. This invention can be used for diabetes screening, diabetes maintenance, identification and quantification of ketosis, explosives detection and formaldehyde detection.
    Type: Grant
    Filed: September 4, 2007
    Date of Patent: September 7, 2010
    Assignee: Southwest Sciences Incorporated
    Inventor: Steven Michael Massick
  • Publication number: 20100136600
    Abstract: There is provided a method of diagnosing a disease state in a subject. The disease state is caused or effected by pneumococcal infection. The method includes obtaining a biological test sample from the subject. The biological sample includes at least one metabolite selected from the group consisting of citrate, trigonelline, acetylcarnitine, acetone, myo-inositol, 3-hydroxybutyrate, glucose and carnitine. A respective concentration of each one of the at least one metabolite is compared with a predetermined concentration value associated with a corresponding one of the at least one metabolite. The predetermined concentration value is indicative of the disease state. For example, the biological sample includes any one of citrate, trigonelline, acetylcamitine, acetone, myoinositol, 3-hydroxybutyrate, glucose and carnitine. As a further example, the biological samples include any combination of citrate, trigonelline, acetylcamitine, acetone, myo-inositol, 3-hydroxybutyrate, glucose and carnitine.
    Type: Application
    Filed: April 14, 2008
    Publication date: June 3, 2010
    Inventors: Carolyn Slupsky, Thomas Marrie
  • Patent number: 7704751
    Abstract: A method of detecting organic vapors is described. More particularly, the method involves the use of an analyte sensor that contains a polymeric material having a relatively large intrinsic porosity and that is capable of fluorescence in the visible region of the electromagnetic spectrum. The method further includes exposing the analyte sensor to an environment that may contain an organic vapor and monitoring the analyte sensor for a change in a fluorescence signal. Although the organic vapor itself typically does not fluoresce in the visible wavelength range, presence of an organic vapor can alter the fluorescence signal of the analyte sensor.
    Type: Grant
    Filed: October 25, 2006
    Date of Patent: April 27, 2010
    Assignee: 3M Innovative Properties Company
    Inventors: Michael C. Palazzotto, Neal A. Rakow, Michael S. Wendland
  • Publication number: 20100075431
    Abstract: A formaldehyde detector (10) includes a detection reagent that produces a color by reaction with formaldehyde. The detector (10) further includes a detection element (30) including: a base material (31) constituting an optical waveguide through which light propagates while repeating total reflection; and a mesoporous layer (32) that is formed on at least part of a light-reflecting surface constituting a surface of the base material (31) and carries the detection reagent. The detector (10) further includes: a light emitter for emitting light to the base material (31); and a light receiver for receiving light emitted from the base material (31). In addition, the detector (10) includes a signal processing part.
    Type: Application
    Filed: September 27, 2007
    Publication date: March 25, 2010
    Inventors: Haoshen Zhou, Takashi Watanabe, Yoonmyung Kang, Kazuhisa Shigemori, Kyouhei Murayama
  • Publication number: 20090275143
    Abstract: In various embodiments, the present disclosure provides a method of detecting triacetone triperoxide. In a particular implementation, the method includes providing an array of titanium nanostructures that include a sensitizing agent. The array is contacted with a fluid sample, such as vapor sample. The resistance of the array is measured. The measured resistance of the array can be used to determine whether the sample includes triacetone triperoxide. The nanostructures are, in some cases, titania nanotubes. The sensitizing agent is, in a specific example, zinc. The present disclosure also provides a triacetone triperoxide sensor that includes an array of nanostructures, at least a portion of which are sensitized with a sensitizer, such as one or more of Li+, Cu2+, In3+, Sb3+, Sc3+, NH4+, Na+, Zn2+, Cd2+, and Ti4+. A plurality of electrical contacts are coupled to the array.
    Type: Application
    Filed: March 6, 2009
    Publication date: November 5, 2009
    Inventors: Manoranjan Misra, Susanta K. Mohapatra, Subarna Bannerjee, Indu B. Mishra
  • Patent number: 7569189
    Abstract: An apparatus for opening and closing a container having a slidable shutter closure moving past the apparatus includes: a rotatable shaft having an axis perpendicular to the direction of travel of the slidable shutter, the shaft being biased against rotation in either direction; a driver for bidirectionally moving the shaft from a position away from the container to a position in the vicinity of the container for opening and closing; and an extension extending outwardly from the rotatable shaft along at least a portion of the shaft into a line of travel, whereby the extension is adapted to engage the shutter closure of the container and move the shutter closure from an open position to a closed position or from a closed position to an open position. A reagent source for an automated analyzer includes: a reagent source which includes a container having a shutter closure which slides between an open and closed position; an apparatus for opening and closing the container.
    Type: Grant
    Filed: March 30, 2005
    Date of Patent: August 4, 2009
    Assignee: Ortho-Clinical Diagnostics, Inc.
    Inventors: Merrit N. Jacobs, Robert A. Burkovich
  • Patent number: 7553450
    Abstract: An irreversible humidity exposure dose indicator device, including a housing sealed at a first end thereof and adapted at a second end thereof to admit ambient gas ingress into an interior volume containing chromogenic material. The chromogenic material in contact with water irreversibly absorbs such water to produce a change whose extent is correlative of cumulative exposure of the device to humidity. The device may be configured as an indicator card including an intermediate permeable membrane coated on a first side thereof with a layer of a deliquescent solid and being in contact on a second side thereof with a layer containing a reactive indicator, with a water-permeable layer adjacent to the layer containing the deliquescent coating, enclosed within a water-impermeable transparent enclosure.
    Type: Grant
    Filed: January 8, 2007
    Date of Patent: June 30, 2009
    Assignee: Appealing Products, Inc.
    Inventors: Amir J. Attar, Dan Edward Stark
  • Patent number: 7514265
    Abstract: The present application describes a reagent system for detecting presence of aldehyde in a sample that includes (i) Component A, which includes bisulfite, pararosalinine, and hydrochloric acid; and (ii) Component B, which includes a solution of hydroxide, wherein the Component A has a pH of from about 1.4 to 1.6.
    Type: Grant
    Filed: October 5, 2004
    Date of Patent: April 7, 2009
    Assignee: Marine Products Tech
    Inventors: Min Jin Yoon, Joong Cheol Lee, Yang Seo Ku
  • Publication number: 20080293151
    Abstract: Provided are a simple method for analyzing aldehydes and ketones in a sample, which does not require a complicated operation such as extraction with a solvent and concentration of the extract; and an analytical apparatus and a fiber-packed needle which are used in the analytical method. Also provided a fiber coated with hydrochloride or sulfate of 2,4-dinitrophenylhydrazine; a needle for microextraction in which the fibers are packed; the analytical apparatus including this needle and a suction device; the method for analyzing aldehydes and ketones in a sample, characterized by comprising sucking the sample through the needle in this analytical apparatus to allow the aldehydes and ketones in the sample to react with 2,4-dinitrophenylhydrazine, thereby converting them to the corresponding 2,4-dinitrophenylhydrazones; desorbing the 2,4-dinitrophenylhydrazones; and introducing the desorbed 2,4-dinitrophenylhydrazones into a chromatograph to analyze them.
    Type: Application
    Filed: August 1, 2008
    Publication date: November 27, 2008
    Inventor: Hiroo WADA
  • Publication number: 20080145947
    Abstract: A method for rapidly detecting the presence of formaldehyde in a urine sample (e.g., urine or a urinary material associated therewith, such as headspace gas located associated with urine) is provided. The method includes contacting the urine sample with a substrate on which is disposed a colorant that is capable of undergoing a detectable color change in the presence of formaldehyde. Without intending to be limited by theory, it is believed that oxidation of the colorant by formaldehyde induces either a shift of the absorption maxima towards the red end of the spectrum (“bathochromic shift”) or towards the blue end of the spectrum (“hypsochromic shift”). The absorption shift provides a color difference that is detectable, either visually or through instrumentation, to indicate the presence of formaldehyde within the urine sample. For example, prior to contact with a urine sample, the colorant may be colorless or it may possess a certain color.
    Type: Application
    Filed: December 14, 2006
    Publication date: June 19, 2008
    Inventors: Rameshbabu Boga, Stephanie M. Martin, Molly K. Smith, Kevin Peter McGrath
  • Patent number: 7087434
    Abstract: An apparatus for measuring the concentration of formaldehyde in an exhaust stream from turbines, internal combustion engines and the like, which apparatus includes a portable housing having a sample gas inlet through which a sample gas for analysis is introduced into the portable housing and an analysis system disposed in the portable housing suitable for analyzing the sample gas for the presence of formaldehyde in the sample gas.
    Type: Grant
    Filed: December 20, 2002
    Date of Patent: August 8, 2006
    Assignee: Gas Technology Institute
    Inventors: James Pey Chen, Paul Drayton, Jim M. McCarthy, Jeffrey A. Panek, John Charles Wagner
  • Patent number: 6913932
    Abstract: A stabilization reagent composition, particularly desirable for stabilizing blood samples containing platelets, contains reactants that generate multiple species of formaldehyde-ammonium complexes; at least one inhibitor of phosphatase enzymatic activity; and at least one inhibitor of protease enzymatic activity. Blood samples and other tissues are stabilized by this composition. Such stabilized samples are produced by methods for stabilizing the tissue by contacting the sample with the composition.
    Type: Grant
    Filed: August 23, 2002
    Date of Patent: July 5, 2005
    Assignee: Beckman Coulter, Inc.
    Inventors: John A. Maples, Lori A. Charie, Daniel James Flagler, Rhonda Ann Mills, Richard Timmons
  • Patent number: 6835573
    Abstract: A test strip, methods for making and using the test strip, and a kit are described, which allow for the simple and efficient determination of the acetaldehyde content in a polyester polymer. The strip and methods have application, for example, in the manufacture of polyethylene terephthalate preforms and containers, where existing methods for testing for acetaldehyde are cumbersome and time consuming.
    Type: Grant
    Filed: August 29, 2001
    Date of Patent: December 28, 2004
    Assignee: Husky Injection Molding Systems Ltd.
    Inventors: Loong-Tak Lim, Michael E. Nicholas, Harold Godwin
  • Patent number: 6818450
    Abstract: The present invention is directed to an analytical method for measuring the concentration of an N-(phosphonomethyl)iminodiacetic acid (“NPMIDA”) substrate, an N-(phosphonomethyl)glycine product, formaldehyde, formic acid, N-methyl-N-(phosphonomethyl)glycine (“NMG”), N-methyl-aminomethylphosphonic acid (MAMPA) or aminomethylphosphonic acid (“AMPA”)) in an aqueous mixture thereof, using infrared spectroscopy. The present invention is also directed to a process for oxidizing an N-(phosphonomethyl)iminodiacetic acid substrate to form a N-(phosphonomethyl)glycine product, and as part of the process, measuring the concentration of at least one reactant, product or byproduct of the oxidation reaction using the analytical method of the present invention and controlling the oxidation process in response to the measurement taken.
    Type: Grant
    Filed: May 17, 2002
    Date of Patent: November 16, 2004
    Assignee: Monsanto Technology LLC
    Inventors: David R. Eaton, Walter Gavlick, Gary Klopf, Arnold Hershman, Denis Forster
  • Publication number: 20040121479
    Abstract: An apparatus for measuring the concentration of formaldehyde in an exhaust stream from turbines, internal combustion engines and the like, which apparatus includes a portable housing having a sample gas inlet through which a sample gas for analysis is introduced into the portable housing and an analysis system disposed in the portable housing suitable for analyzing the sample gas for the presence of formaldehyde in the sample gas.
    Type: Application
    Filed: December 20, 2002
    Publication date: June 24, 2004
    Inventors: James Pey Chen, Paul Drayton, Jim M. McCarthy, Jeffrey A. Panek, John Charles Wagner
  • Patent number: 6706526
    Abstract: A low formaldehyde containing aqueous blood diluent contains an effective amount of ethylenediamine tetraacetic acid, ethylenediamine tetraacetic acid derivative, or combinations thereof; an effective amount of 5-chloro-2-methyl-4-isothiazolin-3-one and 2-methyl-4-isothiazolin-3-one; and an effective amount of 5-bromo-5-nitro-1,3-dioxane. Advantageously, less than about 1 parts per million of formaldehyde is produced in this multipurpose diluent. A method of analyzing a blood sample containing blood cells is conducted by forming a diluted blood sample by mixing a blood sample containing blood cells with this diluent and analyzing the diluted blood sample to determine a physical parameter of the blood cells.
    Type: Grant
    Filed: January 24, 2002
    Date of Patent: March 16, 2004
    Assignee: Coulter International Corp.
    Inventors: Russell F. Lang, Iris L. Payan, Barbara G. Murza, Luisa C. Oramas