Oxygen Containing Patents (Class 436/127)
  • Patent number: 10280131
    Abstract: The invention relates to terpene-derived acids and esters thereof as well as to processes for synthesizing them.
    Type: Grant
    Filed: June 12, 2017
    Date of Patent: May 7, 2019
    Assignee: P2 SCIENCE, INC.
    Inventors: Patrick Foley, Yonghua Yang, Robert Bedoukian, Thomas Killinger
  • Patent number: 9874566
    Abstract: To address the need for scaffold-based oxygen concentration monitoring, a single-component, self-referenced oxygen sensor was made into nanofibers. Electrospinning process parameters were tuned to produce a biomaterial scaffold with specific morphological features. The ratio of an oxygen sensitive phosphorescence signal to an oxygen insensitive fluorescence signal was calculated at each image pixel to determine an oxygenation value. A single component boron dye-polymer conjugate was chosen for additional investigation due to improved resistance to degradation in aqueous media compared to a dye polymer blend. Standardization curves show that in fully supplemented media, the fibers are responsive to dissolved oxygen concentrations less than 15 parts per million. Spatial and temporal ratiometric gradients were observed in vitro radiating outward from the center of a dense adherent cell grouping. Sensor activation in ischemia and cell transplant models in vivo show oxygenation decreases on the scale of minutes.
    Type: Grant
    Filed: August 5, 2015
    Date of Patent: January 23, 2018
    Assignee: University of Virginia Patent Foundation
    Inventors: Kenneth Brayman, Daniel Bowers, Cassandra L. Fraser, Edward A. Botchwey, III
  • Patent number: 9678087
    Abstract: Provided are methods for determining the amount of estrone in a sample using mass spectrometry. The methods generally involve ionizing estrone in a sample and detecting and quantifying the amount of the ion to determine the amount of estrone in the sample.
    Type: Grant
    Filed: November 5, 2014
    Date of Patent: June 13, 2017
    Assignee: Quest Diagnostics Investments Incorporated
    Inventors: Mildred M. Goldman, Richard E. Reitz
  • Patent number: 9425031
    Abstract: A system including a differential mobility spectrometer is described as is a method of operating the system including the differential mobility spectrometer. The method and system involve a) providing ions to the differential mobility spectrometer; b) providing a drift gas to an inlet of the differential mobility spectrometer; c) adjusting a meter to define a selected volumetric flow rate for supplying a modifier liquid to the drift gas; and, d) supplying an actual volumetric flow rate of the modifier liquid to the drift gas, wherein the actual volumetric flow rate is within a percentage deviation from the selected volumetric flow rate.
    Type: Grant
    Filed: May 27, 2009
    Date of Patent: August 23, 2016
    Inventors: Bradley Schneider, Thomas Covey
  • Patent number: 9157877
    Abstract: A process for characterizing a copolymer of ethylene and vinyl acetate (EVA) using a differential calorimetry analysis technique. This process is determining one or more values of characteristic(s) of a sample of EVA copolymer, one of which is a level of crosslinking of the sample. The process makes it possible to determine not only the degree of crosslinking, but also the vinyl acetate content and the molecular mass of an EVA sample, in a simple, rapid, easy and precise manner.
    Type: Grant
    Filed: March 2, 2012
    Date of Patent: October 13, 2015
    Assignees: ARKEMA FRANCE, COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES
    Inventors: Manuel Hidalgo, Franck Medlege
  • Patent number: 9023654
    Abstract: A method for measuring bromate ions includes: an adding step of adding a fluorescent substance whose fluorescence intensity changes by the coexistence of bromate ions to sample water; a measuring step of measuring the fluorescence intensity of the fluorescent substance; a difference calculating step of calculating a difference between the fluorescence intensity measured and a reference fluorescence intensity of reference sample water that contains no bromate ion; and a concentration calculating step of calculating bromate ion concentration from the calculated fluorescence intensity difference. The measuring step includes a step of measuring the fluorescence intensity at any one of a case where an excitation wavelength is 264 nm and an emission wavelength is 400 nm, a case where the excitation wavelength is 264 nm and the emission wavelength is 480 nm, and a case where the excitation wavelength is 300 nm and the emission wavelength is 400 nm.
    Type: Grant
    Filed: January 2, 2014
    Date of Patent: May 5, 2015
    Assignee: Metawater Co., Ltd.
    Inventors: Natsumi Konishi, Eri Hasegawa, Yoshiharu Tanaka, Shukuro Igarashi, Takao Ohtomo
  • Patent number: 8945935
    Abstract: The present invention provides a system and method for diagnosing, monitoring or prognosing Multiple Sclerosis at different stages as well as affording the prediction of disease activity and response to a treatment regimen, using at least one sensor comprising carbon nanotubes or metal nanoparticles, each coated with various organic coatings in conjunction with a pattern recognition algorithm.
    Type: Grant
    Filed: August 1, 2012
    Date of Patent: February 3, 2015
    Assignees: Technion Research & Development Foundation Ltd., Mor Research Applications Ltd., Rappaport Family Institute for Research in the Medical Sciences
    Inventors: Hossam Haick, Ariel Miller
  • Patent number: 8936943
    Abstract: Provided are methods of detecting the presence or amount of a vitamin D metabolite in a sample using mass spectrometry. The methods generally comprise ionizing a vitamin D metabolite in a sample and detecting the amount of the ion to determine the presence or amount of the vitamin D metabolite in the sample. Also provided are methods to detect the presence or amount of two or more vitamin D metabolites in a single assay.
    Type: Grant
    Filed: April 26, 2013
    Date of Patent: January 20, 2015
    Assignee: Quest Diagnostics Investments, Inc.
    Inventors: Nigel J. Clarke, Brett Holmquist, Gloria Kwang-Ja Lee, Richard E. Reitz
  • Patent number: 8916385
    Abstract: Provided are methods for determining the amount of estrone in a sample using mass spectrometry. The methods generally involve ionizing estrone in a sample and detecting and quantifying the amount of the ion to determine the amount of estrone in the sample.
    Type: Grant
    Filed: December 13, 2007
    Date of Patent: December 23, 2014
    Assignee: Quest Diagnostics Investments, Inc.
    Inventors: Mildred M. Goldman, Nigel J. Clarke, Richard E. Reitz
  • Patent number: 8883512
    Abstract: A serum-based biomarker for diagnosing gestational diabetes, preeclampsia and fetal growth restriction (GDM-PREEC-FGR), based on retinoid profiling, and a method for diagnosing GDM-PREEC-FGR that specifically uses a blood sample to identify and measure the concentrations of retinol (vitamin A alcohol), retinyl esters and retinoic acid.
    Type: Grant
    Filed: March 26, 2012
    Date of Patent: November 11, 2014
    Inventor: Anthony R. Mawson
  • Publication number: 20140329330
    Abstract: A soil tester is disclosed, and comprises a housing and a sampling apparatus. The housing includes an interior sampling chamber configured to receive a sample container. The sampling apparatus comprises a photodetector and a light source. The photodetector is mounted along a portion of the interior sampling chamber and has a variable resistance determined by a property of incident light. The light source is mounted to the interior sampling chamber in a transmissive orientation relative to the photodetector so that a beam of light can be transmitted from the light source to the photodetector through the interior sampling chamber. A display on the housing is responsive to the photodetector.
    Type: Application
    Filed: May 6, 2014
    Publication date: November 6, 2014
    Applicant: Luster Leaf Products, Inc.
    Inventors: Mark B. Williams, Larry L. Holbein, Christopher G. Holbein
  • Patent number: 8871521
    Abstract: Ketoacidosis is an extreme and uncontrolled form of ketosis, which is a normal response to prolonged fasting. Embodiments of this invention test the ketone level of a patient by measuring the ketone bodies in breath condensation. Some embodiments include a device for medical testing comprising a hollow container, comprising powder mixture of sodium nitroferricyanide, ammonium sulfate and silica and a liquid including an ammonium hydroxide solution.
    Type: Grant
    Filed: March 8, 2012
    Date of Patent: October 28, 2014
    Assignee: Akers Biosciences, Inc.
    Inventor: Raymond F. Akers, Jr.
  • Patent number: 8871519
    Abstract: The present invention relates to methods for qualifying material for using in the cleaning of alkylene oxide equipment. Qualified material is not expected to contribute to the formation of determinable amounts of alkylene oxide by-products. Methods of cleaning alkylene oxide equipment, and alkylene oxide processes incorporating these methods are also provided.
    Type: Grant
    Filed: May 10, 2012
    Date of Patent: October 28, 2014
    Assignee: Dow Technology Investments LLC
    Inventor: Paul Victor Hinman
  • Publication number: 20140302613
    Abstract: A means for detecting active oxygen in the human body, which quantitatively detects the amount of active oxygen remaining in the body by applying urine to a detection paper, and is characterized by providing a means for detecting active oxygen in the human body, which detects the amount of active oxygen by submerging a test strip into urine, on which has been applied a color indicating agent that changes color by reacting with malondialdehyde (MDA) and to which has been coupled a support stick, and observing color change. The present invention can affordably and simply identify active oxygen, because the test strip changes color when simply wetted with urine and the test does not require additional technically skilled laboratory staff or expensive equipment. Also, the invention enables simple testing regardless of time and space since a specific facility is unnecessary for the test, thereby providing another advantage of general usage.
    Type: Application
    Filed: April 22, 2014
    Publication date: October 9, 2014
    Applicant: DFI Co.,Ltd.
    Inventors: Jung-geon Yun, Yong-ae Park, Tae-wan Kim, Sang-hoon Kang
  • Patent number: 8852951
    Abstract: Provided are methods of detecting the presence or amount of a dihydroxyvitamin D metabolite in a sample using mass spectrometry. The methods generally comprise ionizing a dihydroxyvitamin D metabolite in a sample and detecting the amount of the ion to determine the presence or amount of the vitamin D metabolite in the sample. In certain preferred embodiments the methods include immunopurifying the dihydroxyvitamin D metabolites prior to mass spectrometry. Also provided are methods to detect the presence or amount of two or more dihydroxyvitamin D metabolites in a single assay.
    Type: Grant
    Filed: January 28, 2013
    Date of Patent: October 7, 2014
    Assignee: Quest Diagnostics Investments Incorporated
    Inventors: Brett Holmquist, Nigel J. Clarke, Anne Caston-Balderrama, Richard E Reitz
  • Patent number: 8846405
    Abstract: A method for detecting the presence of an aldehyde in a sample comprises steps of exposing the sample at room temperature to a test medium to catalyze the formation of optically detectable quantities of a product within a time period of no more than 60 minutes and without applying any external heat to the sample or test medium, the test medium comprising a indicator that is a nucleophilic compound having acidic protons at the nucleophilic center and at least one acid, and measuring the optical changes that occur as a result of the catalysis.
    Type: Grant
    Filed: July 16, 2012
    Date of Patent: September 30, 2014
    Assignee: Oxford Biomedical Research, Inc.
    Inventors: Enrique Martinez, II, Denis Callewaert, Donald J. VerLee
  • Patent number: 8822233
    Abstract: New chemiluminescent compounds, stable in aqueous buffers, for use in biological assaying include acridane-based compounds and 1,2-dioxetanes. Among the new acridane-based compounds are water-soluble acridanes, enhancer coupled acridanes, bis and tris-acridanes as well as acridane-1,2-dioxetanes. Among the new 1,2-dioxetanes are electron deficient group-containing dioxetanes and tethered bis-1,2-dioxetanes. The 1,2-dioxetanes are useful as substrates for various enzymes. The acridanes can be admixed with an oxidizing agent. an aqueous buffer and, optionally, a stabilizer to form a substrate or reagent formulation useful for assaying, inter alia, HRP.
    Type: Grant
    Filed: August 23, 2010
    Date of Patent: September 2, 2014
    Inventors: Brij Pal Giri, Dinesh Dagli, Pritam Singh
  • Patent number: 8815605
    Abstract: The invention relates to methods and kits for determining the total organic acid content in a coolant sample.
    Type: Grant
    Filed: April 19, 2012
    Date of Patent: August 26, 2014
    Assignee: Dexsil Corporation
    Inventors: Theodore B. Lynn, Timothy D. Lynn
  • Patent number: 8809064
    Abstract: Implementations and techniques for sensing hydroxyl radicals in ozone washing systems are generally disclosed. In some examples, the disclosure describes an ozone washing system having an ozone reservoir coupled to a washing machine and a control unit configured to direct the insertion of ozone from the ozone reservoir to the washing machine based on sensed hydroxyl radical levels in fluid samples from the washing machine.
    Type: Grant
    Filed: March 9, 2011
    Date of Patent: August 19, 2014
    Assignee: Empire Technology Development LLC
    Inventor: Seth Miller
  • Patent number: 8778693
    Abstract: A subject of the invention is a kit for the identification, characterization and quantification by a single detection of the carboxylic, thiol and amine functional groups contained in a sample.
    Type: Grant
    Filed: January 26, 2011
    Date of Patent: July 15, 2014
    Assignees: Universite d'Aix Marseille, Centre National de la Recherche Scientifique
    Inventors: Jean-Luc Boudenne, Bruno Coulomb, Fabien Robert-Peillard, Edwin Barco Palacio
  • Patent number: 8778085
    Abstract: A dissolved nitrogen concentration monitoring method is used for monitoring a dissolved nitrogen concentration of a cleaning liquid when an ultrasonic wave is irradiated onto the cleaning liquid in which a substrate is dipped. The method includes measuring an amount of increase of a dissolved oxygen concentration of the cleaning liquid resulting from an oxygen molecule generated from a water molecule as a result of a radical reaction caused by ultrasonic wave irradiation. A dissolved nitrogen concentration of the cleaning liquid is calculated from the measured amount of increase of dissolved oxygen concentration based on a predetermined relationship between a dissolved nitrogen concentration and an amount of increase of dissolved oxygen concentration.
    Type: Grant
    Filed: December 13, 2011
    Date of Patent: July 15, 2014
    Assignee: Siltronic AG
    Inventors: Teruo Haibara, Etsuko Kubo, Yoshihiro Mori, Masashi Uchibe
  • Patent number: 8759111
    Abstract: Porous sol-gel material essentially consisting of units of one or more first polyalkoxysilanes chosen from the following compounds: (chloromethyl)triethoxysilane; 1,3-dimethyltetramethoxydisiloxane; ethyl trimethoxysilane; triethoxy(ethyl)silane; triethoxymethylsilane; triethoxy(vinyl)silane; trimethoxymethylsilane; trimethoxy(vinyl)silane; tetraethoxysilane or tetramethoxysilane (TMOS) and of units of one or more second polyalkoxysilanes chosen from the following compounds: (N-(3-(trimethoxysilyl)propyl)ethylenediamine; 3-aminopropyltriethoxysilane (APTES) and 3-aminopropyltrimethoxysilane, in a first polyalkoxysilane/second polyalkoxysilane molar ratio of 1/0.01 to 1/1, optionally comprising a probe molecule, method of preparation and applications in the trapping of monocyclic aromatic hydrocarbons and other pollutants or in their detection.
    Type: Grant
    Filed: July 10, 2009
    Date of Patent: June 24, 2014
    Assignees: CEA—Commisariat a l'Energie Atomique et aux Energies Alternatives, CNRS—Centre National de la Recherche Scientifique
    Inventors: Sabine Crunaire, Thu-Hoa Tran-Thi
  • Patent number: 8758690
    Abstract: A sterilization indicator having a compound that is of the heating type when put into contact with atoms of oxygen O and/or nitrogen N; and a thermochromic dye, in thermal contact with the compound.
    Type: Grant
    Filed: February 22, 2013
    Date of Patent: June 24, 2014
    Assignee: Societe pour la Conception des Applications des Techniques Electroniques
    Inventors: André Ricard, Francis Dieras, Michel Sixou, Sandrine Villeger, Cristina Canal, Pilar Erra
  • Patent number: 8741151
    Abstract: The scale inhibitors in a variety of aqueous systems, or a part or sample thereof, also including one or more dissolved interfering ions, are separated therefrom and analyzed, such scale inhibitors comprising a polymer containing at least one anionic functional group, e.g., a strong acid functional group or a phosphonate or phosphate ester, and such analysis including treating these aqueous systems with a cationic substrate or a free cation.
    Type: Grant
    Filed: April 4, 2006
    Date of Patent: June 3, 2014
    Assignee: Rhodia UK Limited
    Inventors: Mike Hails, Chris Jones
  • Patent number: 8728824
    Abstract: The invention relates to the detection of fatty acids. In a particular aspect, the invention relates to methods for detecting very long chain fatty acids and branched chain fatty acids by mass spectrometry.
    Type: Grant
    Filed: June 21, 2012
    Date of Patent: May 20, 2014
    Assignee: Quest Diagnostics Investments Inc.
    Inventor: Scott Goldman
  • Publication number: 20140134746
    Abstract: A method for marking a petroleum hydrocarbon or a liquid biologically derived fuel by adding to the petroleum hydrocarbon or liquid biologically derived fuel at least one compound having formula (I), wherein R represents C1-C18 alkyl, C3-C18 alkenyl or C3-C18 alkynyl.
    Type: Application
    Filed: June 28, 2012
    Publication date: May 15, 2014
    Applicant: ANGUS CHEMICAL COMPANY
    Inventors: George D. Green, Raymond J. Swedo
  • Patent number: 8679851
    Abstract: A method for determining a turbidity point and a free carbohydrate buffer coefficient of an iron-carbohydrate complex. The method includes: (1) contacting the complex with an acid; (2) determining hydrogen ion concentrations and solution turbidities of the complex in acid degradation; and (3) mathematically fitting the data, to obtain the turbidity point of the complex and the free carbohydrate buffer coefficient through mathematical treatment. A method for evaluating the safety of the iron-carbohydrate complex with the turbidity point and the free carbohydrate buffer coefficient.
    Type: Grant
    Filed: January 13, 2010
    Date of Patent: March 25, 2014
    Assignee: Nanjing Lifenergy R&D Co., Ltd
    Inventors: Wen Fang, Chuanzheng Hua, Jie Yang, Guoxin He, Shoujun Xiong
  • Patent number: 8679846
    Abstract: The invention provides a sterilization indicator (17), characterized in that it comprises: a compound (21) that is of the heating type when put into contact with atoms of oxygen O and/or nitrogen N; and a thermochromic dye (19), in thermal contact with the compound (21).
    Type: Grant
    Filed: December 20, 2007
    Date of Patent: March 25, 2014
    Assignee: Societe pour la Conception des Applications des Techniques Electroniques
    Inventors: André Ricard, Francis Dieras, Michel Sixou, Sandrine Villeger, Cristina Canal, Pilar Erra
  • Patent number: 8663996
    Abstract: A system for measuring the oxygen concentration of a gas includes a catalytic reactor, first and second temperature sensors and a control unit. The catalytic reactor includes a combustion catalyst that supports the catalytic combustion of hydrocarbon fuel vapor in a gas stream. The first temperature sensor is located upstream of the catalytic reactor for sensing an upstream temperature of the gas stream, and the second temperature sensor is located downstream of the catalytic reactor for sensing a downstream temperature of the gas stream. The control unit compares the upstream temperature and the downstream temperature to determine the oxygen concentration of the gas stream.
    Type: Grant
    Filed: April 26, 2010
    Date of Patent: March 4, 2014
    Assignee: Hamilton Sundstrand Corporation
    Inventor: William Beeson
  • Patent number: 8658429
    Abstract: A photoluminescent oxygen probe including a tack with a layer of a pressure-sensitive adhesive and an oxygen-sensitive photoluminescent element on the underside of the head. The probe is effective for sensing oxygen concentration within an enclosed space by puncturing the container defining the enclosed space the with the probe's shank and adhering the underside of the probe's head to the container so as to sealingly surround the puncture, thereby placing the oxygen-sensitive photoluminescent dye on the underside of the probe's head into sensible communication with the enclosed space through the puncture hole.
    Type: Grant
    Filed: August 6, 2012
    Date of Patent: February 25, 2014
    Assignee: Mocon, Inc.
    Inventors: Daniel W. Mayer, John Eastman
  • Patent number: 8647876
    Abstract: An oxygen permeability measuring apparatus for measuring an oxygen permeation rate of oxygen barrier film in a dark room is provided. A container is charged with inert gas, and sealed hermetically by use of the oxygen barrier film at least partially. A chemiluminescent compound is contained in the container, for emitting light by oxidation with the oxygen. A photon detector detects photons emitted by the chemiluminescent compound so as to determine an amount of the oxygen permeated through the oxygen barrier film. Preferably, the container includes a container body. An opening is formed in the container body, and closed hermetically by the oxygen barrier film attached thereto. The photon detector is disposed inside or outside the container. The oxygen permeation rate is equal to or less than 10?2 cc/m2·day·atm. The chemiluminescent compound includes tetrakis(dimethylamino)ethylene.
    Type: Grant
    Filed: March 31, 2011
    Date of Patent: February 11, 2014
    Assignee: Fujifilm Corporation
    Inventors: Tomoyuki Shimoda, Yoshio Inagaki, Kimiaki Miyamoto
  • Patent number: 8617898
    Abstract: Quantification of vitamin D2, vitamin D3, and the monohydroxy and diihydroxy metabolites of vitamin D2 and vitamin D3, can comprise labeling analytes with mass spectrometry (MS) tagging reagents and performing LC-MSMS analysis of the labeled analytes. The labeled analytes can include a labeled standard and can have distinct retention times on a reversed phase column, as well as distinct masses. Under high energy collisions, reporter groups can be generated. The intensity or the peak area detected for each reporter group can be used for quantitation. In some embodiments, a one-step tagging reagent is used that is a dienophile-containing, labeled Diels Alder reagent.
    Type: Grant
    Filed: January 25, 2011
    Date of Patent: December 31, 2013
    Assignee: DH Technologies Development Pte. Ltd.
    Inventors: Subhakar Dey, Sasi K. Pillai, Brian Williamson, Subhasish Purkayastha
  • Patent number: 8609428
    Abstract: The invention relates to an assay to test for pyrethroids in a sample. The assay is particularly useful for testing material treated with pyrethroids, such as bed netting and the like.
    Type: Grant
    Filed: February 27, 2009
    Date of Patent: December 17, 2013
    Assignee: London School of Hygiene & Tropical Medicine
    Inventors: Harparkash Kaur, Teunis Eggelte
  • Patent number: 8518707
    Abstract: A method of monitoring breakthrough of an adsorbent bed consisting for example of ion-exchange resins, used during a stage of purification of an ester stream containing glycerin, obtained for example in a vegetable or animal oil and aliphatic monoalcohol transesterification process, permits the instantaneous detection of the presence of glycerol (glycerin) in the ester stream by arranging a turbidimeter at the adsorbent bed outlet.
    Type: Grant
    Filed: July 20, 2009
    Date of Patent: August 27, 2013
    Assignee: IFP Energies Novelles
    Inventors: Abdelhakim Koudil, Karin Barthelet, Laurent Bournay
  • Publication number: 20130209435
    Abstract: The invention provides methods of determining risk for stroke in a patient, as well as methods of determining a subject's need for anti-coagulation therapy. In exemplary embodiments, the method comprises measuring a level of derivatives of reactive oxygen metabolites (DROMs) in a biological sample obtained from the subject, wherein an increased level of DROMs, relative to a control level, is indicative of the subject's need for anticoagulation therapy. Further provided are methods of decreasing risk of stroke in a subject, methods of determining the efficacy of a therapeutic agent, methods of monitoring a subject's risk of stroke, and kits.
    Type: Application
    Filed: July 29, 2011
    Publication date: August 15, 2013
    Applicant: THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS
    Inventors: Samuel Dudley, Smita Negi
  • Patent number: 8501100
    Abstract: An oxygen sensor includes a metalloporphyrin for detecting oxygen levels. The oxygen sensors may also include a light source and a detector. The sensors are configured to measure changes in spectra in response to the redox reaction. They can detect a variety of samples for presence and changes in oxygen concentration in both solution and gaseous form.
    Type: Grant
    Filed: June 16, 2010
    Date of Patent: August 6, 2013
    Assignee: Empire Technology Development LLC
    Inventor: Toshimi Fukui
  • Patent number: 8426212
    Abstract: There is provided a method of monitoring for the presence of phosphate esters in jet fuel. The method comprises obtaining from a jet fuel source a jet fuel test sample suspected of containing phosphate esters. The method further comprises combining the jet fuel test sample with a polar solvent and a nonpolar solvent to form a mixture. The method further comprises agitating the mixture. The method further comprises extracting the polar solvent from the mixture. The method further comprises performing a combined gas chromatography and mass spectrometer analysis of the polar solvent to monitor for the presence of any phosphate esters and to obtain an actual concentration level of any phosphate esters. The method further comprises comparing the actual concentration level of any phosphate esters with a calibration standard concentration of phosphate esters in clean jet fuel.
    Type: Grant
    Filed: October 6, 2010
    Date of Patent: April 23, 2013
    Assignee: The Boeing Company
    Inventors: Gregory J. Werner, Gary Robert Tamas
  • Patent number: 8415166
    Abstract: The present invention provides a device for the detection of a peroxide-based explosive, in particular, triacetone triperoxide (TATP), which is based on a molecular controlled semiconductor resistor (MOCSER) and composed of at least one insulating or semi-insulating layer, at least one conducting semiconductor layer, two conducting pads and a layer of multifunctional organic molecules capable of adsorbing molecules of the peroxide-based explosive. The invention further provides an array of semiconductor devices for the selective detection of a peroxide-based explosive, as well as a method for the selective detection of vapors of a peroxide-based explosive in a gaseous mixture using this array.
    Type: Grant
    Filed: May 12, 2009
    Date of Patent: April 9, 2013
    Assignee: Yeda Research and Development Co. Ltd.
    Inventors: Ron Naaman, Eyal Capua, Roberto Cao
  • Patent number: 8415167
    Abstract: It is an object of the present invention to provide: an oxygen indicator aqueous solution for an oxygen detector that has high heat resistance, can be stored at room temperature, and can maintain an excellent ability to detect oxygen, regardless of the atmospheric temperature; an oxygen detector; and a method for manufacturing an oxygen detector. In order to achieve this object, there is provided an oxygen indicator aqueous solution for an oxygen detector that is an aqueous solution comprising reducing saccharides, a basic substance, and a redox dye reduced by the reducing saccharides, the aqueous solution comprising, as the reducing saccharides, a monosaccharide as a first component and a reducing trisaccharide as a second component. In addition, there is provided a manufacturing method preferred for the manufacturing of the oxygen detector.
    Type: Grant
    Filed: October 19, 2010
    Date of Patent: April 9, 2013
    Assignee: Powdertech Co., Ltd.
    Inventors: Ryuichi Kodama, Mitsuyuki Sato
  • Patent number: 8409865
    Abstract: Embodiments of the present invention are directed to methods and kits for determining the presence or absence, and the amount if present, of vitamin D analogs in samples. One embodiment of the present method for detecting the presence or absence of vitamin D analogs in a sample comprises the steps of adding an effective amount of a multiple charge cationic agent to the sample to form a cationic treated sample. The effective amount of a multiple charge cationic agent enhances the signal from vitamin D analogs upon analysis by mass spectroscopy.
    Type: Grant
    Filed: February 20, 2009
    Date of Patent: April 2, 2013
    Assignee: Waters Technologies Corp.
    Inventors: Lisa Jane Calton, Kendon Stuart Graham
  • Patent number: 8377704
    Abstract: Provided herein are methods of detecting anions in solution. In particular, the methods can be used to detect trace anions in solution. For example, the anions can be present in an amount of between about 500 femtomoles to about 10 millimoles.
    Type: Grant
    Filed: October 19, 2010
    Date of Patent: February 19, 2013
    Assignee: NUtech Ventures
    Inventors: Stephen DiMagno, Ronald Cerny
  • Patent number: 8367414
    Abstract: Methods and systems are provided that utilize measured isotopic abundance data to correlate a product to the synthesis process by which it was made. By utilizing the principles described herein, isotopic process profiles for synthetic products can be constructed, products of unknown origin can be inferentially identified to the processes by which they were made, and synthesis processes can be monitored for consistency of process parameters.
    Type: Grant
    Filed: May 30, 2007
    Date of Patent: February 5, 2013
    Inventor: John P. Jasper
  • Patent number: 8367001
    Abstract: The present invention generally relates to luminescent and/or optically absorbing compositions and/or precursors to those compositions, including solid films incorporating these compositions/precursors, exhibiting increased luminescent lifetimes, quantum yields, enhanced stabilities and/or amplified emissions. The present invention also relates to sensors and methods for sensing analytes through luminescent and/or optically absorbing properties of these compositions and/or precursors. Examples of analytes detectable by the invention include electrophiles, alkylating agents, thionyl halides, and phosphate ester groups including phosphoryl halides, cyanides and thioates such as those found in certain chemical warfare agents. The present invention additionally relates to devices and methods for amplifying emissions, such as those produced using the above-described compositions and/or precursors, by incorporating the composition and/or precursor within a polymer having an energy migration pathway.
    Type: Grant
    Filed: November 15, 2010
    Date of Patent: February 5, 2013
    Assignee: Massachusetts Institute of Technology
    Inventors: Timothy M. Swager, Shi-Wei Zhang
  • Patent number: 8361801
    Abstract: The present invention comprises a method for identifying the presence or absence of a pulmonary embolism using a combination of tests and brightline thresholds. The first test is a blood based test measuring D-Dimer concentration and the second test is a respiratory analysis that determines a carboximetry ratio. If the measured D-Dimer value is at or above a threshold indicative of concern and the carboximetry value is equal to or less than a carboximetry ratio threshold, pulmonary embolism is present. If the measured D-Dimer value is at or above a threshold indicative of concern and the respiratory analysis yields a carboximetry ratio greater than the carboximetry ratio threshold, test results are inconclusive and additional testing is required to determine whether a pulmonary embolism is present.
    Type: Grant
    Filed: April 14, 2009
    Date of Patent: January 29, 2013
    Assignee: DEKA Products Limited Partnership
    Inventors: Gregory R. Lanier, Jr., Derek G. Kane
  • Publication number: 20130017611
    Abstract: A method for fabricating a sensor material for detecting molecular contaminants, including the steps of: providing an aqueous solution of a metal oxide precursor; mixing titanium dioxide nanotubes with the aqueous solution of the metal oxide to form a mixture; adjusting a pH value of the mixture with a weak base until the pH value is neutral; dispersing the mixture in water and heating the mixture; and filtering the mixture to retain a solid part, and calcining the solid part under a continuous flow of oxygen to form metal oxide loaded titanium dioxide nanotubes. The disclosure also provides a sensor material and a detecting method using the sensor material for ppm-ppb-ppt concentration level detection of molecular contaminants.
    Type: Application
    Filed: November 28, 2011
    Publication date: January 17, 2013
    Inventors: Shou-Nan LI, Hong-Ping LIN, Hui-Ya SHIH, Wen-An HSIEH, Jhih-Jie LIN
  • Patent number: 8334141
    Abstract: The detecting and monitoring of solid structure or phase transformation, such as those used for testing the formation of gas hydrates and their inhibition by chemical additives may be conducted in a multi-test assembly of laboratory bench scale loops. The test loop contains a fluid that includes water and hydrate-forming guest molecules such as methane, ethane, carbon dioxide and the like at hydrate-forming conditions of low temperature and high pressure. A small bit or “pig” may be circulated through the test loop at variable speeds to circulate the fluid in the loop. The pig may be moved or impelled through the test loop remotely. The exterior of the pig and/or the interior of the loop may be smooth and/or have a friction-reducing coating thereon to facilitate movement of the pig through the loop. The formation of hydrates may be monitored with consistent and reproducible results.
    Type: Grant
    Filed: October 4, 2010
    Date of Patent: December 18, 2012
    Assignee: Baker Hughes Incorporated
    Inventor: Jun Tian
  • Patent number: 8323978
    Abstract: A calibration device and method of using the device to calibrate an analytical instrument capable of reading a photoluminescent oxygen probe. The device includes at least (a) a first mass of an oxygen sensitive photoluminescent dye retained within a hermetically sealed space so as to isolate the dye from environmental oxygen, and in fluid communication with an activated metal-air battery whereby any oxygen permeating into the hermetically sealed space is quickly consumed by the battery, and (b) a second mass of an oxygen sensitive photoluminescent dye in fluid communication with an environmental concentration of oxygen.
    Type: Grant
    Filed: May 20, 2011
    Date of Patent: December 4, 2012
    Assignee: Mocon, Inc.
    Inventors: Timothy A. Ascheman, Daniel W. Mayer
  • Patent number: 8304251
    Abstract: Systems and methods are disclosed to automatically detect the presence of a substance on a test swipe by capturing a background image of the test swipe; applying one or more test chemicals to a test swipe; adjusting the temperature of the test swipe to a predetermined temperature range; capturing an in-situ image of the test swipe after the application of chemical at the predetermined temperature range; subtracting the background image from the in-situ image; generating a difference value from the two images; and searching a known database to identify the substance.
    Type: Grant
    Filed: February 18, 2009
    Date of Patent: November 6, 2012
    Assignee: Chem Spectra, Inc.
    Inventors: Jeffrey Haas, Douglas Haas
  • Publication number: 20120276650
    Abstract: A method for determining a turbidity point and a free carbohydrate buffer coefficient of an iron-carbohydrate complex. The method includes: (1) contacting the complex with an acid; (2) determining hydrogen ion concentrations and solution turbidities of the complex in acid degradation; and (3) mathematically fitting the data, to obtain the turbidity point of the complex and the free carbohydrate buffer coefficient through mathematical treatment. A method for evaluating the safety of the iron-carbohydrate complex with the turbidity point and the free carbohydrate buffer coefficient.
    Type: Application
    Filed: January 13, 2010
    Publication date: November 1, 2012
    Applicant: NANJING LIFENERGY R&D CO., LTD.
    Inventors: Wen Fang, Chuanzheng Hua, Jie Yang, Guoxin He, Shoujun Xiong
  • Patent number: 8282798
    Abstract: A gas probe, in particular a lambda probe for the analysis of exhaust gases from a mobile internal combustion engine, includes at least one protective device, at least partly surrounding a sensitive sensor element of the gas probe, which comes into contact with a gas. The at least one protective device includes a gas contact face which at least partly has a hygroscopic surface.
    Type: Grant
    Filed: October 10, 2006
    Date of Patent: October 9, 2012
    Assignees: EMITEC Gesellschaft fuer Emissionstechnologie mbH, Audi AG
    Inventors: Rolf Brück, Bernhard Pfalzgraf, Bodo Odendall