Process Or Composition For Sterility Or Package Integrity Test Patents (Class 436/1)
  • Patent number: 6676901
    Abstract: The present invention provides an oxygen indicator comprising: an oxygen indicating agent including a substrate and an oxygen indicator composition fixed at the surface of the substrate; and a single-sided self-adhesive plastic member having a self-adhesive layer on one side thereof, wherein the oxygen indicating agent is provided over the single-sided sedlf-adhesive plastic member by causing the oxygen indicator composition to closely contact the self-adhesive layer. Moreover, this invention provides a deoxidizer package with an oxygen indicating function, to which the oxygen indicator is pasted. This invention further provides a method and apparatus for fixing the oxygen indicator to an object.
    Type: Grant
    Filed: June 2, 2000
    Date of Patent: January 13, 2004
    Assignee: Mitsubishi Gas Chemical Company, Inc.
    Inventors: Hidetoshi Hatakeyama, Shigeo Tobari, Shigeharu Iwauchi, Masahiko Ohsawa
  • Patent number: 6656429
    Abstract: A test pack for testing the adequacy of air removal in a prevacuum sterilizer.
    Type: Grant
    Filed: November 19, 1999
    Date of Patent: December 2, 2003
    Assignee: Propper Manufacturing Co., Inc.
    Inventor: John D. Dyckman
  • Publication number: 20030207453
    Abstract: A sterilization monitor includes a substrate and an monitor composition. The monitor composition contains a colorant and a halogen source and undergoes a distinct color change when exposed to a peracid. The sterilization monitor can be used to monitor a sterilization process involving a peracid. A sterilization monitoring device, including a sterilization monitor enclosed in a housing having a vapor permeable barrier, can also be used to monitor a sterilization process.
    Type: Application
    Filed: August 2, 2001
    Publication date: November 6, 2003
    Applicant: Minnesota Mining and Manufacturing Company, a Minnesota corporation
    Inventors: Ramon T. Ignacio, Allan P. Piechowski
  • Publication number: 20030199095
    Abstract: An ink composition for sensing carbon dioxide gas contains a pH indicator formed using a combination of two or more types of pH indicator components, binder, and solvent and allows easy visual observation of color changes of an indicating portion caused by the concentration of carbon dioxide gas. When the ink composition is applied to a carbon dioxide indicator and package, a pinhole and poor seal of a carbon-dioxide-ambient package are easily found.
    Type: Application
    Filed: June 14, 2002
    Publication date: October 23, 2003
    Inventors: Kohei Yuyama, Minoru Oka, Hiroshi Honda, Shin Hamazaki, Shinya Ochiai, Noe Obinata, Hiroyuki Mizuma
  • Patent number: 6630352
    Abstract: A sterilant challenge device (1), for use in testing the efficiency of the air removal stage of a sterilization cycle in a sterilizer, includes a tube (2) of thermally-insulating material, the bore of which is closed at one end (3) and open at the other for the entry of sterilant. A plurality of thermally-conductive masses (4) is located around the tube (2) and thermally-separated from one another by air gaps (14), and a temperature sensor is located in an opening (16) in one of the masses adjacent the closed end of the tube. An outer casing (5) defines an air space around the thermally-conductive masses and thermally insulates the masses from the heat in the sterilizer.
    Type: Grant
    Filed: March 28, 2001
    Date of Patent: October 7, 2003
    Assignee: 3M Innovative Properties Company
    Inventors: Hackler Reiner, Robbert-Jan Hermsen, Wolfgang Kaps
  • Publication number: 20030185706
    Abstract: A device for monitoring the expiration of goods includes a substrate and an unreacted composition affixed thereto which is intrinsically reactive to one or both of its thermal environment and the length of time following activation. The reactivity results in a color formation of the composition with the color formation being a single color upon reaction to one of said thermal environment or length of time and multiple colors upon reaction to both. The device may be a label affixed to a container containing the goods to be monitored or may be printed directly on a container.
    Type: Application
    Filed: August 23, 2002
    Publication date: October 2, 2003
    Inventor: Hans O. Ribi
  • Patent number: 6627443
    Abstract: The present invention relates to new color compositions which are especially suitable to be used in oxygen indicators. The compositions comprise iron(II), an agent containing pyrogallol entities and an organic acid.
    Type: Grant
    Filed: April 27, 2000
    Date of Patent: September 30, 2003
    Assignee: Fresenius Kabi AB
    Inventors: Åke Stenholm, Lars Karlsson, Anders Löfgren, Bo Nystrom, Otto Skolling
  • Publication number: 20030170901
    Abstract: A electronic system for tracking and monitoring articles to be subjected to a sterilization cycle is disclosed. The method uses a sterilization indicator and electronically links sterilization information with the articles subjected to the sterilization process. The indicator allows a sterilization cycle to be monitored without the need for a user to subjectively distinguish between color, quality or intensity of display patterns.
    Type: Application
    Filed: November 25, 2002
    Publication date: September 11, 2003
    Applicant: 3M Innovative Properties Company
    Inventors: Roland C. Kippenhan, Steven S. Kirckof, Philip A. Bolea, Richard M. Rumble, Rodney K. Hehenberger, Ramon T. Ignacio
  • Publication number: 20030153085
    Abstract: A system and method for sorting of objects that includes a pathway network that has a plurality of pathways and one or more branch points. A fluid composition including one or more objects can be transported through the pathway network, where one or more of the objects are analyzed and sorted at one or more branch points based on the analysis of the objects.
    Type: Application
    Filed: January 10, 2003
    Publication date: August 14, 2003
    Applicant: NeuroBioTex
    Inventors: James F. Leary, Christopher J. Frederickson
  • Patent number: 6596542
    Abstract: A chemical actinometer for determining the absolute level of exposure to ultraviolet light of a fluid to be treated for disinfection purposes. The actinometer includes a translucent sample cell through which the chemical actinometric fluid flows. The area of exposure of the actinometric fluid is controlled by allowing the ultraviolet light to pass through only a portion of the sample cell. A suitable actinometric fluid is a combination of iodide and iodate in a solution. The sample cell is positioned within an ultraviolet disinfection reactor at a position to receive ultraviolet light from the ultraviolet light source.
    Type: Grant
    Filed: January 8, 2001
    Date of Patent: July 22, 2003
    Inventor: Christopher R. Schulz
  • Publication number: 20030133837
    Abstract: A re-usable sterilizer test device is disclosed which is comprised of at least two parts which are releasably connected together. An indicator device which changes colour in the presence of steam after a certain time period is deposited within the two parts. One or both of the bodies is manufactured from a material having a predetermined degree of porosity as regards steam and is generally cylindrical or spherical so that the outer surface of said one or both bodies forms a significant and substantial portion of the external surface of the assembled device. Steam penetrates the porous body and passes into a cavity inside the body from where the steam can move internally of the device through suitable passageways and into a chamber where the indicator is located.
    Type: Application
    Filed: October 7, 2002
    Publication date: July 17, 2003
    Inventor: Richard Bancroft
  • Patent number: 6593142
    Abstract: A polymeric food spoilage sensor comprises a polymer containing a polyazamacrocyclic transition metal complex. The complex selectively binds biogenic amines, such as cadaverine, putrescine and histamine, which are released by food spoilage microorganisms. The polymer undergoes a detectable color change upon exposure to biogenic amine, thus indicating that food spoilage has probably occurred. In one embodiment, the polymer is molecularly imprinted with the biogenic amine to impart selective binding affinity. The polymer is easily incorporated in common food containers and can be employed in fiber optic detection devices.
    Type: Grant
    Filed: October 26, 2001
    Date of Patent: July 15, 2003
    Assignee: The Johns Hopkins University
    Inventors: Craig A. Kelly, George M. Murray, O. Manuel Uy
  • Publication number: 20030118478
    Abstract: A sterilization indicator that presents a visually distinct and uniform color transition after having been passed through sterilizing conditions. This sterilization indicator has a base layer with an indicator compound applied to at least an indicating region thereon. It also has a raised lamina attached to the base layer so as to substantially surround the indicating region.
    Type: Application
    Filed: February 4, 2003
    Publication date: June 26, 2003
    Applicant: 3M Innovative Properties Company
    Inventor: Rodney K. Hehenberger
  • Publication number: 20030113228
    Abstract: A dual bar code for detecting contamination. When no contamination is present, a first bar code identifies the product. When contamination is present a second bar code identifies the presence of contaminants.
    Type: Application
    Filed: June 5, 2002
    Publication date: June 19, 2003
    Inventors: Robert M. Goldsmith, Catherine H. Goldsmith, James G. Woodaman
  • Publication number: 20030113922
    Abstract: A method and system for detecting chemical or biological hazards in items is provided. A plurality of incoming mail mailboxes each include a sampler to sample air from a letter that is tested using a first sensor. Source information corresponding to hazard flagged mail pieces is utilized to block mail from that source at other mailboxes.
    Type: Application
    Filed: December 19, 2001
    Publication date: June 19, 2003
    Applicant: Pitney Bowes Inc.
    Inventors: Robert A. Cordery, Karin A. Russo, Ronald P. Sansone
  • Publication number: 20030087441
    Abstract: A sterilization process challenge device has a sterilization indicator contained within a container; and a variable diffusion restriction into said container.
    Type: Application
    Filed: November 2, 2001
    Publication date: May 8, 2003
    Inventors: Anthony Lemus, Debra Timm
  • Patent number: 6551555
    Abstract: An apparatus for determining exposure to an oxidative sterilant is described. The apparatus includes a chemical indicator for indicating exposure to the oxidative sterilant and a biological indicator for determining the effectiveness of the exposure to the oxidative sterilant. The chemical indicator has a metallic surface with a non-pH sensitive permanent indicator on the surface for indicating exposure to the oxidative sterilant. The chemical indicator may be on a self-contained biological indicator. The biological indicator and chemical indicator may be inside a test pack, where the test pack restricts sterilant flow to the indicators.
    Type: Grant
    Filed: December 19, 2000
    Date of Patent: April 22, 2003
    Assignee: Ethicon, Inc.
    Inventors: Patricia A. Antonoplos, Henry K. Hui, Alireza Ebrahim, Leslie A. Feldman, Nitu Kohli
  • Patent number: 6534006
    Abstract: A sterilization indicator that presents a visually distinct and uniform color transition after having been passed through sterilizing conditions. This sterilization indicator has a base layer with an indicator compound applied to at least an indicating region thereon. It also has a raised lamina attached to the base layer so as to substantially surround the indicating region.
    Type: Grant
    Filed: August 30, 2001
    Date of Patent: March 18, 2003
    Assignee: 3M Innovative Properties Company
    Inventor: Rodney K. Hehenberger
  • Publication number: 20030008400
    Abstract: There is disclosed a process for melting a luminescent oxygen sensitive compound into extruded polymer films. Specifically, there is disclosed a process for thermal melting of oxygen-sensitive indicators into common packaging polymers used for commercial packaging of products, such as foods. The oxygen-sensitive indicators can be used for real-time monitoring of oxygen in commercial packaging operations.
    Type: Application
    Filed: June 25, 2001
    Publication date: January 9, 2003
    Inventors: David L. Putnam, Todd Hubbard
  • Patent number: 6491881
    Abstract: An apparatus for monitoring the concentration of an oxidative gas or vapor includes a chemical substance which reacts with the oxidative gas or vapor to produce a heat change. A temperature probe is coupled to the chemical substance and adapted to respond to the heat change. The temperature probe can be coupled to the chemical substance by a carrier, and can include a reference temperature probe. Additionally, a method of using the apparatus is described, as well as a sterilization system which utilizes the apparatus.
    Type: Grant
    Filed: December 19, 2000
    Date of Patent: December 10, 2002
    Assignee: Ethicon, Inc.
    Inventors: Ben Fryer, Debra Timm, Szu-Min Lin, Henry Hui, Sam Nutt
  • Patent number: 6488890
    Abstract: A sterilization indicator having sterilizing agent sensitive indicia is described. The indicator allows a sterilization cycle to be monitored without the need for a user to subjectively distinguish between color, quality or intensity of display patterns.
    Type: Grant
    Filed: August 5, 1999
    Date of Patent: December 3, 2002
    Assignee: 3M Innovative Properties Company
    Inventor: Steven S. Kirckof
  • Patent number: 6485978
    Abstract: A sterilization indicator having sterilizing agent sensitive indicia is described. The indicator allows a sterilization cycle to be monitored without the need for a user to subjectively distinguish between color, quality or intensity of display patterns.
    Type: Grant
    Filed: August 5, 1999
    Date of Patent: November 26, 2002
    Assignee: 3M Innovative Properties Company
    Inventors: Steven S. Kirckof, Phillip A. Bolea
  • Patent number: 6485979
    Abstract: A electronic system for tracking and monitoring articles to be subjected to a sterilization cycle is disclosed. The method uses a sterilization indicator and electronically links sterilization information with the articles subjected to the sterilization process. The indicator allows a sterilization cycle to be monitored without the need for a user to subjectively distinguish between color, quality or intensity of display patterns.
    Type: Grant
    Filed: August 5, 1999
    Date of Patent: November 26, 2002
    Assignee: 3M Innovative Properties Company
    Inventors: Roland C. Kippenhan, Steven S. Kirckof, Phillip A. Bolea, Richard M. Rumble
  • Patent number: 6479293
    Abstract: In the present invention, a temperature indicating material is prepared by incorporating, in a rewritable base system which comprises an electron donating compound, an electron accepting compound and a reversal material and undergoes color changes with temperature and time, a thermochromism controller which changes a rate of crystal to amorphous or phase-separation to non-phase-separation rate. Upon color changes with an environmental temperature, the thermochromism controller undergoes crystallization or phase separation to have a function as a place for reaction and contributes to the color changes of the temperature indicating material. The incorporation of the thermochromism controller therefore makes it possible to impart the resulting temperature indicating material with improved sensitivity to temperature at around an environmental temperature and a high S/N ratio.
    Type: Grant
    Filed: February 4, 2000
    Date of Patent: November 12, 2002
    Assignee: Toshiba Tec Kabushiki Kaisha
    Inventors: Toshiyuki Tamura, Yuichiro Hatanaka
  • Patent number: 6479016
    Abstract: A dual bar code for detecting food contamination. When no contamination is present a first bar code identifies the food product. When contamination is present a second bar code identifies the presence of contaminants.
    Type: Grant
    Filed: July 24, 2000
    Date of Patent: November 12, 2002
    Assignee: California South Pacific Investors
    Inventors: Robert M. Goldsmith, Catherine H. Goldsmith, James G. Woodaman
  • Publication number: 20020142469
    Abstract: This invention discloses a method for detecting a leak from a sealed optical device. The method includes steps of: A) injecting a target gas with no performance interference to the sealed optical device for leak detection followed by sealing the sealed optical device. B) placing the sealed device in a leak testing chamber and measuring a background level of the target gas in the leak testing chamber. C) heating the sealed device to a gas-expelling temperature for expelling the target gas from the leak in the sealed optical device. And, D) detecting the target gas in a one-part-per million (PPM) range in the leak-detecting chamber for an comparing with the background level of the target gas for determining the leak in the sealed optical device.
    Type: Application
    Filed: March 5, 2001
    Publication date: October 3, 2002
    Applicant: Oplink Communications, Inc.
    Inventors: Jason Li, Steven Guoxin Zhu
  • Patent number: 6451272
    Abstract: A monitor of the concentration of an oxidative gas or vapor comprises a chemical coupled to a temperature probe, such as by a carrier. Addtionally, the monitor is used in a method of monitoring the concentration of an oxidative gas or vapor and in a sterilization system operated by a user. By utilizing an output signal from the temperature probe to measure the heat produced in an exothermic reaction between the monitored oxidative gas or vapor and the chemical of the monitor, the concentration of the monitored oxidative gas or vapor can be determined. The present invention represents an improvement over the monitors described in the prior art since it is more simplified, and can provide information on the local concentration of an oxidative gas or vapor at various positions within a chamber, and can be operated in size-restricted volumes. Additionally, a method of using the monitor is described, as well as a sterilization system which utilizes the monitor.
    Type: Grant
    Filed: December 21, 1999
    Date of Patent: September 17, 2002
    Assignee: Ethicon, Inc.
    Inventors: Ben Fryer, Debra Timm, Szu-Min Lin
  • Publication number: 20020121629
    Abstract: The present invention relates to a chemical indicator that is used to determine whether instruments and other products to be sterilized have experienced a sterilization treatment process or to confirm whether sterilization has been efficiently performed, by the color tone change of the indicator when sterilizing medical instruments and other products and the like by a hydrogen peroxide low temperature plasma sterilizing method.
    Type: Application
    Filed: February 28, 2002
    Publication date: September 5, 2002
    Inventors: Masao Mikumo, Kenji Kazama, Yoshio Jo
  • Patent number: 6440744
    Abstract: A sterilization monitor includes a substrate and an monitor composition. The monitor composition contains a colorant and a halogen source and undergoes a distinct color change when exposed to a peracid. The sterilization monitor can be used to monitor a sterilization process involving a peracid. A sterilization monitoring device, including a sterilization monitor enclosed in a housing having a vapor permeable barrier, can also be used to monitor a sterilization process.
    Type: Grant
    Filed: January 5, 2000
    Date of Patent: August 27, 2002
    Assignee: 3M Innovative Properties Company
    Inventors: Ramon T. Ignacio, Allan P. Piechowski
  • Publication number: 20020076357
    Abstract: A cassette is received within a sleeve having an open end. Specially folded flaps at the open end are applied to center the cassette in the sleeve and to reduce a width of the open end of the sleeve.
    Type: Application
    Filed: December 15, 2000
    Publication date: June 20, 2002
    Inventors: Michael Hahs, Su-Syin Wu, Edward V. Quoss
  • Patent number: 6406914
    Abstract: The present composition for use in radiation exposure dose-history indicators comprises a radioactive ray-absorber and/or a radioactive ray-excited fluorescence-emitting agent, a color-developing and electron-donating organic compound and an active species-generating organic compound, which can initiate the color development of the electron-donating organic compound through the application of radioactive rays. The indicator sheet for indicating the radiation exposure dose-history comprises a matrix sheet; and a color-developing layer, which contains a color-developing and electron-donating organic compound, an active species-generating organic compound, which can initiate the color development of the electron-donating organic compound through the application of radioactive rays, and a radioactive ray-absorber and/or a radioactive ray-excited fluorescence-emitting agent and which is applied to at least part of the surface of the matrix sheet.
    Type: Grant
    Filed: February 25, 2000
    Date of Patent: June 18, 2002
    Assignee: Nichiyu Giken Kogyo Co., Ltd.
    Inventors: Yoshiaki Kaburaki, Daisuke Harumoto, Hiromichi Mizusawa, Yukiyo Niwa, Hitoshi Shirase
  • Publication number: 20020072079
    Abstract: The present invention relates to a food contamination detector associated with a double bar code, given the trademark GILBAR™ by the owner of the present invention, that includes coded indicia used to identify the presence of conditions indicative of microbial contamination in food, including toxic contaminants, bacterial metabolites, and other microbial secretions. Of the two bar code symbols associated with the food contamination detector, the first identifies the food product in terms of the type of food, the quantity, the price and the like, while the second bar code symbol is designed to identify the presence of contaminants. When contamination is not detected, the first bar code symbol is scanner readable, whereas the second bar code symbol is not. Once contamination is detected, bars in both bar code symbols can appear or disappear causing the first bar code symbol to become scanner unreadable and the second bar code symbol to become scanner readable.
    Type: Application
    Filed: August 10, 2001
    Publication date: June 13, 2002
    Applicant: Sira Technologies, Inc.
    Inventor: James G. Woodaman
  • Patent number: 6403036
    Abstract: A test glass slide for an automated biological reaction apparatus is disclosed. The test slide monitors to operational temperature of the apparatus for maintenance/quality control purposes by means of at least two temperature-sensitive indicators, which change visual states once a predetermined temperature threshold is reached. The thresholds correspond generally to the specified temperature range for the protocol performed by the apparatus.
    Type: Grant
    Filed: September 29, 1999
    Date of Patent: June 11, 2002
    Assignee: Ventana Medical Systems, Inc.
    Inventors: Paula M. Rodgers, Kimberly K. C. Christensen
  • Patent number: 6399387
    Abstract: The present invention relates to new color compositions which are especially suitable to be used in oxygen indicators. The compositions comprise iron(II), an agent containing pyrogallol entities and an organic acid.
    Type: Grant
    Filed: January 22, 1999
    Date of Patent: June 4, 2002
    Assignee: Pharmacia AB
    Inventors: Åke Stenholm, Lars Karlsson, Anders Löfgren, Bo Nyström, Otto Skolling
  • Patent number: 6395551
    Abstract: A device for indicating residence time in a liquid disinfection solution, the device comprising a visually observable detector of exposure of the device to the solution, the device being selected such that upon exposure of the device to the solution the detector visibly changes after a predetermined time interval.
    Type: Grant
    Filed: May 13, 1996
    Date of Patent: May 28, 2002
    Assignee: 3M Innovative Properties Company
    Inventors: Cary A. Kipke, George Van Dyke Tiers
  • Publication number: 20020051733
    Abstract: An apparatus for determining exposure to an oxidative sterilant is described. The apparatus includes a chemical indicator for indicating exposure to the oxidative sterilant and a biological indicator for determining the effectiveness of the exposure to the oxidative sterilant. The chemical indicator has a metallic surface with a non-pH sensitive permanent indicator on the surface for indicating exposure to the oxidative sterilant. The chemical indicator may be on a self-contained biological indicator. The biological indicator and chemical indicator may be inside a test pack, where the test pack restricts sterilant flow to the indicators.
    Type: Application
    Filed: December 19, 2000
    Publication date: May 2, 2002
    Inventors: Patricia A. Antonoplos, Henry K. Hui, Alireza Ebrahim, Leslie A. Feldman, Nitu Kohli
  • Patent number: 6378906
    Abstract: A system, container, and a label for monitoring the use of a container. The label is ideally inserted into the wall of the container. The label preferably includes an indicating ink that incrementally changes color or changes shade when certain external energy sources are applied. The labeled container can be used in a system of monitoring, characterizing, and recording information and traits regarding containers wherein the incremental changes in the indicating ink are measured. The information, such as counting cycles of container use, is preferably machine-readable, as well as human-readable.
    Type: Grant
    Filed: December 8, 2000
    Date of Patent: April 30, 2002
    Assignee: Morgan Adhesives Company
    Inventor: Thomas J. Pennaz
  • Publication number: 20020039792
    Abstract: A sterilization indicator that presents a visually distinct and uniform color transition after having been passed through sterilizing conditions. This sterilization indicator has a base layer with an indicator compound applied to at least an indicating region thereon. It also has a raised lamina attached to the base layer so as to substantially surround the indicating region.
    Type: Application
    Filed: August 30, 2001
    Publication date: April 4, 2002
    Inventor: Rodney K. Hehenberger
  • Publication number: 20020034823
    Abstract: A sterilant challenge device, for use in testing the efficiency of the air removal stage of a sterilization cycle in a sterilizer. In a preferred embodiment, the device includes a tube that is closed at one end and open at the other for the entry of sterilant, a plurality of thermally-conductive masses the tube, and at least one temperature sensor. When the challenge device is located in a sterilizer, the penetration of sterilant along the bore of the tube during a sterilization cycle, is inhibited by the accumulation of air and/or non-condensable gas within the bore resulting from the condensation of moisture on the walls of the bore. By measuring the temperature inside the device adjacent the closed end of the tube, the efficiency of the sterilization cycle can be determined.
    Type: Application
    Filed: November 27, 2001
    Publication date: March 21, 2002
    Applicant: 3M Innovative Properties Company
    Inventors: Anton Kuepper, Brian Kirk
  • Publication number: 20020022246
    Abstract: A sterilization system uses a sterilization process monitoring device which is capable of indicating the efficacy of the sterilization process. To enhance accuracy of the monitoring function, the monitoring device is located in such a fashion that an antimicrobial agent used in the process can only reach the monitor through an area containing the article to be sterilized.
    Type: Application
    Filed: December 21, 2000
    Publication date: February 21, 2002
    Inventors: Szu-Min Lin, Su-Syin Wu
  • Patent number: 6346417
    Abstract: A sterilization monitor includes a substrate and an monitor composition. The monitor composition contains a colorant and a halogen source and undergoes a distinct color change when exposed to a peracid. The sterilization monitor can be used to monitor a sterilization process involving a peracid. A sterilization monitoring device, including a sterilization monitor enclosed in a housing having a vapor permeable barrier, can also be used to monitor a sterilization process.
    Type: Grant
    Filed: January 5, 2000
    Date of Patent: February 12, 2002
    Assignee: 3M Innovative Properties Company
    Inventors: Ramon T. Ignacio, Allan P. Piechowski
  • Patent number: 6325974
    Abstract: Package (1) for decayable foodstuffs (2), consisting of a package material (3) and forming a mainly closed package space (4) and a mainly closed indicator space (5) for an indicator (6).
    Type: Grant
    Filed: May 6, 1999
    Date of Patent: December 4, 2001
    Assignee: Valtion Teknillinen Tutkimuskeskus
    Inventors: Raija Ahvenainen, Timo Pullinen, Eero Hurme, Maria Smolander, Matti Siika-Aho
  • Patent number: 6323032
    Abstract: A sterilant challenge device, for use in testing the efficiency of the removal stage of a sterilization cycle in a sterilizer. In a preferred embodiment, the device includes a tube that is closed at one end and open at the other for the entry of sterilant, a plurality of thermally-conductive masses the tube, and at least one temperature sensor. When the challenge device is located in a sterilizer, the penetration of sterilant along the bore of the tube during a sterilization cycle, is inhibited by the accumulation of air and/or non-condensable gas within the bore resulting from the condensation of moisture on the walls of the bore. By measuring the temperature inside the device adjacent the closed end of the tube, the efficiency of the sterilization cycle can be determined.
    Type: Grant
    Filed: March 17, 1998
    Date of Patent: November 27, 2001
    Assignee: 3M Innovative Properties Company
    Inventors: Anton Kuepper, Brian Kirk
  • Patent number: 6307674
    Abstract: A method and apparatus for projecting an image of a patient to intersect a display screen which is nonperpendicular to an adjacent portion of an optical path and adjacent a sterile operative field. A video projector system and accompanying optics impart at least one of a tilted focal plane or depth of focus to the projected image. The optical path of the projected image is located adjacent the surgical field. An initially sterile display screen is located in the optical path adjacent the sterile field so that a normal to the screen is noncoincident with the optical path and the projected image on the screen is of constant focus across the screen. The initially sterile display screen may be degradable upon cleaning and resterilization so that a new screen must be used with each procedure, thus insuring the optical quality and sterility of the screen. The display screen may be supported adjacent the surgical field by an articulated rod assembly.
    Type: Grant
    Filed: October 10, 1997
    Date of Patent: October 23, 2001
    Assignee: LaserSurge, Inc.
    Inventors: Jude S Sauer, John F Hammond
  • Publication number: 20010021531
    Abstract: The disclosure describes food contamination detectors adapted to be used with vacuum packages and package systems including such detectors.
    Type: Application
    Filed: May 14, 2001
    Publication date: September 13, 2001
    Applicant: Sira Technologies
    Inventor: Robert M. Goldsmith
  • Patent number: 6287518
    Abstract: A sterilization monitor includes a substrate and an monitor composition. The monitor composition contains a colorant and a halogen source and undergoes a distinct color change when exposed to a peracid. The sterilization monitor can be used to monitor a sterilization process involving a peracid. A sterilization monitoring device, including a sterilization monitor enclosed in a housing having a vapor permeable barrier, can also be used to monitor a sterilization process.
    Type: Grant
    Filed: February 5, 1998
    Date of Patent: September 11, 2001
    Assignee: 3M Innovative Properties Company
    Inventors: Ramon T. Ignacio, Allan P. Piechowski
  • Patent number: 6270724
    Abstract: The present invention relates to a food contamination detector associated with a double bar code, given the trademark GILBAR™ by the owner of the present invention, that includes coded indicia used to identify the presence of conditions indicative of microbial contamination in food, including toxic contaminants, bacterial metabolites, and other microbial secretions. Of the two bar code symbols associated with the food contamination detector, the first identifies the food product in terms of the type of food, the quantity, the price and the like, while the second bar code symbol is designed to identify the presence of contaminants. When contamination is not detected, the first bar code symbol is scanner readable, whereas the second bar code symbol is not. Once contamination is detected, bars in both bar code symbols can appear or disappear causing the first bar code symbol to become scanner unreadable and the second bar code symbol to become scanner readable.
    Type: Grant
    Filed: April 7, 1999
    Date of Patent: August 7, 2001
    Assignee: California South Pacific Investors
    Inventor: James G. Woodaman
  • Patent number: 6261843
    Abstract: A method and metal test pattern for monitoring metal corrosion susceptibility for integrated circuit wafers. Test patterns having an array of metal circles to simulate contact regions, an array of metal strips to simulate electrode regions, and a blanket metal layer to simulate bulk metal regions are formed. A first number of defects per unit area for the test patterns is measured, using a defect scan system. The test pattern wafers are then subjected to environmental stress conditions for a first time and a second number of defects per unit area for the test patterns is measured, again using a defect scan system. The difference between the second number and the first number is compared with a critical number. If excessive corrosion occurs the process for producing wafers is corrected before continuing to process product wafers.
    Type: Grant
    Filed: December 10, 1998
    Date of Patent: July 17, 2001
    Assignee: Taiwan Semiconductor Manufacturing Company
    Inventors: Chao-Hsin Chang, Hsien-Wen Chang, Chih-Chien Hung, Kuang-Hui Chang
  • Publication number: 20010006818
    Abstract: A novel label may be used in a novel sterilization tracking system. The label preferably has first and second portions and a first and second liners. Perforations may preferably attach the first portion to the second portion. The label is particularly suitable for use in monitoring and/or tracking hydrogen peroxide sterilization procedures.
    Type: Application
    Filed: February 1, 2001
    Publication date: July 5, 2001
    Applicant: 3M Innovative Properties Company
    Inventors: Anita Amhof, Urs Jauslin, Ramon T. Ignacio, Florian Weinig, Christian Stoop
  • Patent number: 6232128
    Abstract: The invention relates to a bicarbonate-containing medical solution package. The package comprises a gas-permeable plastic container holding a bicarbonate-containing medical solution and a gas-impermeable plastic packaging member containing the gas-permeable plastic container. A carbon-dioxide atmosphere is established in the space between the container and packaging member. In addition, a pH indicating device is contained within the space between the container and packaging member. The pH indicating device is a gas-permeable plastic packet containing a bicarbonate-containing fluid (similar to the medical solution) and a pH indicator. The pH indicator undergoes a change in color in response to a change in pH of the fluid. Use of this package allows the easy monitoring of a change in pH and consequent aging of the medical solution due to prolonged storage or damage to the outer packaging member.
    Type: Grant
    Filed: December 16, 1998
    Date of Patent: May 15, 2001
    Assignee: Otsuka Pharmaceutical Factory, Inc.
    Inventors: Seiichiro Iguchi, Shino Shinomiya, Rika Hamamoto, Akiyo Abe, Masatoshi Inai, Keiichi Kawakami