Carbonyl Bonded Directly To The Ring System Patents (Class 512/16)
  • Patent number: 11866403
    Abstract: The present invention provides a carboxylic acid ester compound represented by formula (1) that is useful as a fragrance component or as a formulated fragrance material, wherein R1 is —COOR, wherein R is an alkyl group having 1 to 4 carbon atoms.
    Type: Grant
    Filed: May 28, 2019
    Date of Patent: January 9, 2024
    Assignee: Mitsubishi Gas Chemical Company, Inc.
    Inventors: Yutaka Matsuura, Tomohiko Hakamata
  • Patent number: 9834738
    Abstract: The present invention is directed to a novel fragrance compound of octahydro-4,7-methano-1H-indene-5-acetaldehyde.
    Type: Grant
    Filed: December 13, 2013
    Date of Patent: December 5, 2017
    Inventors: Anubhav P. S. Narula, James Anthony Lasome, Richard A. Weiss, Michael G. Monteleone
  • Publication number: 20150005214
    Abstract: The present invention concerns compounds of formula (I) in the form of any one of its stereoisomers or a mixture thereof, and wherein one dotted line represents a carbon-carbon single or double bond and the others a carbon-carbon single bond; each R, independently from each other, represents a hydrogen atom or a methyl or ethyl group provided that at least one of said R groups represents a methyl or ethyl group; and R1 represents a methyl or ethyl group; and their use in perfumery to impart odor notes of the woody type having cedar, ambery, patchouli and/or rooty aspect.
    Type: Application
    Filed: December 20, 2012
    Publication date: January 1, 2015
    Inventor: Anthony A. Birkbeck
  • Patent number: 8877704
    Abstract: Disclosed are certain compounds according to the general formula (I) and their use as flavoring and fragrancing compounds, as well as fragranced and flavored compositions comprising the compounds of formula (I), and methods for providing a flavor or fragrance to compositions and articles utilizing the compounds of formula (I).
    Type: Grant
    Filed: October 11, 2013
    Date of Patent: November 4, 2014
    Assignee: Givaudan SA
    Inventors: Jean-Pierre Bachmann, Felix Flachsmann
  • Patent number: 8022030
    Abstract: The present invention relates to the field of perfumery. More particularly, it concerns co-polymers, derived from a maleic anhydride derivative and a ethylenic derivative, comprising at least one ?-oxy or ?-thio carbonyl moiety capable of liberating an active molecule such as, for example, an ?,?-unsaturated ketone, aldehyde or carboxylic ester. The present invention concerns also the use of polymers or co-polymers in perfumery as well as the perfuming compositions or perfumed articles comprising the invention's compounds.
    Type: Grant
    Filed: October 5, 2007
    Date of Patent: September 20, 2011
    Assignee: Firmenich SA
    Inventors: Damien Berthier, Andreas Herrmann
  • Publication number: 20110182832
    Abstract: Perfume ingredients have been investigated and classified for their effectiveness in detaching biofilms from surfaces. Based on this classification, perfume compositions that are effective in assisting biofilm detachment can be formulated, whilst also allowing a degree of freedom in formulation that permits consideration of the hedonic properties of the composition. The compositions can be used in a wide range of perfumed consumer products, such as personal, domestic and industrial products, e.g. hard surface cleaning products, dental care products, and deodorant products.
    Type: Application
    Filed: April 13, 2006
    Publication date: July 28, 2011
    Applicant: QUEST INTERNATIONAL SERVICES B.V.
    Inventors: David Jonathan Bradshaw, Alan Forbes Provan, Christopher James Ioannou, John Martin Behan, Keith Douglas Perring
  • Patent number: 7888309
    Abstract: This invention relates to substituted cyclooctenes of the formula I, wherein X and R are defined in the specification.
    Type: Grant
    Filed: September 1, 2009
    Date of Patent: February 15, 2011
    Assignee: Givaudan SA
    Inventors: Thierry Granier, Jerzy A. Bajgrowicz, Andreas Hanhart
  • Patent number: 7691802
    Abstract: Novel compounds of formula I and their use in flavour and fragrance compositions. R1 to R13 have the meaning as described in the specification.
    Type: Grant
    Filed: June 20, 2003
    Date of Patent: April 6, 2010
    Assignee: Givaudan SA
    Inventor: Andreas Goeke
  • Patent number: 7648955
    Abstract: A fragrance composition is provided comprising from about 10% wt to about 40% wt of a residual accord, the residual accord comprising perfume raw materials (PRMs) selected from at least three of the five defined classes. In addition, personal care compositions comprising the defined fragrance composition are also provided.
    Type: Grant
    Filed: November 4, 2004
    Date of Patent: January 19, 2010
    Assignee: The Procter & Gamble Company
    Inventors: Zerlina Guzdar Dubois, Lynette Anne Makins Holland
  • Patent number: 7378383
    Abstract: The present invention relates to the use as perfuming ingredient of a decaline derivative of formula wherein R1 is a lower alkyl, the R2 to R5 are hydrogen atoms or lower alkyls and at least one dotted line is a double bond, which is a useful perfuming ingredient of the woody or woody-citrus type.
    Type: Grant
    Filed: May 6, 2005
    Date of Patent: May 27, 2008
    Assignee: Firmenich SA
    Inventors: Robert Moretti, Olivier Etter
  • Patent number: 7312187
    Abstract: Described are polyalkylbicylic chemical derivatives for use a fragrance ingredients having the generic structure: wherein m=0 or 1; wherein X is methyl or hydrogen; wherein R1, R2, R3 and R4 each represents methyl or ethyl with the proviso that when X is methyl, each of R1, R2, R3 and R4 is methyl and when X is hydrogen, one of R1, R2, R3 and R4 is ethyl; and wherein R6 represents hydrogen or methyl. Methods for using and making these compounds are also disclosed.
    Type: Grant
    Filed: September 26, 2003
    Date of Patent: December 25, 2007
    Assignee: International Flavors & Fragrances Inc.
    Inventors: Anubhav P. S. Narula, Edward Mark Arruda
  • Patent number: 7256170
    Abstract: The present invention relates to the perfumery industry. It concerns more particularly an alcohol, ester, ether or ketone derivative having a spiro-type skeleton, the latter being substituted by short alkyl groups. The invention also relates to the use of the invention compounds as perfuming ingredients, able to impart a woody and/or aromatic, as well as to the perfumed articles or perfuming compositions comprising as active ingredient a compound of formula (I).
    Type: Grant
    Filed: October 8, 2003
    Date of Patent: August 14, 2007
    Assignee: Firmenich SA
    Inventors: Christian Vial, Robert Moretti, Alain Charpilloz, Peter Fankhauser, Piero Fantini
  • Patent number: 7160852
    Abstract: The compound according to the formula set forth below and the use of the compound in creating fragrances, and scents in items such as perfumes, colognes and personal care products is disclosed.
    Type: Grant
    Filed: August 7, 2003
    Date of Patent: January 9, 2007
    Assignee: International Flavors & Fragrances Inc
    Inventors: Anthony T. Levorse, Jr., Anubhav P. S. Narula, Edward Mark Arruda, Charles E. J. Beck
  • Patent number: 6958395
    Abstract: The present invention relates to a method by which saccharide compounds can be prepared in a very easy way. This method comprises the steps of: (a) attaching at least one saccharide to a cyclic or acyclic diene, (b) reacting the saccharide-containing diene obtained in step (a) or a commercially available saccharide-containing diene with a dienophile by Diels-Alder reaction.
    Type: Grant
    Filed: August 22, 2001
    Date of Patent: October 25, 2005
    Assignee: Deutsches Krebsforschungszentrum Stiftung des Offentlichen Rechts
    Inventors: Manfred Wiessler, Hans-Christian Kliem, Bernd Sauerbrei, Birgit Schmauser
  • Patent number: 6949680
    Abstract: A compound of formula wherein Y represents a pyridyl group, or a phenyl group of formula wherein R3 represents a hydrogen atom, a CF3 group or an alkoxy group, R4 represents a hydrogen atom, an alkyl group, or a CF3 group, R5 represents a hydrogen atom, an alkyl group, a CF3 group or an alkoxy group, and R1 and R2 are the substituents of a terminal alkene of formula wherein R1 represents an alkyl or alkylene group, a mono- or poly-cycloalkyl group, or a phenyl group that optionally includes one or several hetero-atoms of oxygen, nitrogen, phosphorous or sulfur; R2 represents a hydrogen atom, an alkyl or alkylene group, a mono- or poly-cycloalkyl group, or a phenyl group that optionally includes one or several hetero-atoms of oxygen, nitrogen, phosphorous and sulfur.
    Type: Grant
    Filed: October 15, 2002
    Date of Patent: September 27, 2005
    Assignee: Firmenich SA
    Inventor: Andreas Herrmann
  • Publication number: 20040186043
    Abstract: The present invention relates to the field of perfumery, and more precisely to a compound of formula (I) 1
    Type: Application
    Filed: March 2, 2004
    Publication date: September 23, 2004
    Inventor: Alvin Scott Williams
  • Patent number: 6632788
    Abstract: The compound according to the formula set forth below where A is B is or A and B together form the ring structure and X, R′ and R are independently H and CH3 and m=0 or 1. and the use of the compound in creating fragrances, and scents in items such as perfumes, colognes and personal care products is disclosed.
    Type: Grant
    Filed: May 17, 2001
    Date of Patent: October 14, 2003
    Assignee: International Flavors & Fragrances Inc.
    Inventors: Anthony T. Levorse, Jr., Anubhav P.S. Narula, Edward Mark Arruda, Charles E.J. Beck
  • Patent number: 6239314
    Abstract: The invention relates to compounds of the general formula in which R1 to R7 are, independently, H, methyl or ethyl, R8+R9 together form methylene (—CH2—) or a single bond, or R1+R2 together form —(CH2)n—, with n being 3 or 4, or R3+R5 or R5+R7 represent methylene or a single bond; and the presence of at least one cyclopropane ring in the molecule is compulsory and the side chain can be saturated or contains one double bond in position &agr;,&bgr; or &bgr;,&ggr;, a process for the manufacture of these compounds, compounds used to perform the process and the use of these compounds as an odorant or as an ingredient of an odorant composition.
    Type: Grant
    Filed: October 5, 2000
    Date of Patent: May 29, 2001
    Assignee: Givaudan Roure (International) SA
    Inventors: Jerzy A. Bajgrowicz, Georg Frater
  • Patent number: 6211153
    Abstract: Methods for treating prostate cancer are disclosed. The methods of the invention generally feature administration to a subject of an LHRH-R antagonist, in combination with a second therapy. In one embodiment, this second therapy is performance of a procedure that removes or destroys prostatic tumor tissue, such as a radical prostatectomy, cryosurgery or X-ray therapy (external or interstitial). In another embodiment, the second therapy is treatment with an LHRH-R agonist, either simultaneous with or subsequent to LHRH-R antagonist therapy. The methods of the invention can further involve administering an antiandrogen and/or an inhibitor of sex steroid biosynthesis to the subject in combination with the LHRH-R antagonist.
    Type: Grant
    Filed: November 11, 1999
    Date of Patent: April 3, 2001
    Assignee: Praecis Pharmaceuticals, Inc.
    Inventors: Marc B. Garnick, Christopher J. Molineaux, Malcolm L. Gefter
  • Patent number: 5492887
    Abstract: It was found that 8-exo-formyl-2,6-exo-tricyclo[5.2.1.0.sup.2,6 ]decane having the constitution and stereochemistry of formula (I) possesses particularly useful olfactory properties which are clearly superior to those of the 8-endo-epimer and which already have an effect if compound (I) is enriched with mixtures of 8-exo- and 8-endo-epimers. Compound (I) can therefore be advantageously used, in pure or enriched form, as a scent or as a component of perfume compositions. To prepare an enriched epimer mixture, a mixture obtained in a known manner (U.S. Pat. No. 3,270,061) and having an exo/endo ratio of 1.45:1 is brought into equilibrium by base catalysis, preferably by the action of alkali hydroxides in alcoholic solution, to give an exo/endo ratio of 5.25:1. Alternatively, the enriched epimer mixture can be prepared starting from 8-formyl-2,6-exo-tricyclo[5.2.1.0.sup.2,6 ]decene-3(4), catalytically hydrogenated for example with palladium coal and then optionally brought into equilibrium.
    Type: Grant
    Filed: December 11, 1992
    Date of Patent: February 20, 1996
    Assignee: Dragoco Gerberding & Co. GmbH
    Inventors: Ernst-Joachim Brunke, Claus-Hermann Kappey, Bernd Holscher, Hartmut Struwe
  • Patent number: 5401720
    Abstract: The present invention relates, inter alia, to novel alkyl tetralin aldehyde compounds having fragrant musk-like aroma.
    Type: Grant
    Filed: January 21, 1994
    Date of Patent: March 28, 1995
    Assignee: Union Camp Corporation
    Inventor: Walter C. Frank
  • Patent number: 5185318
    Abstract: Compound of formula ##STR1## wherein a) indexes m and n are identical and stand each for an integer number equal to zero, symbols R.sup.1 and R.sup.2 are identical and represent each a hydrogen atom, or are different and represent each a hydrogen atom or a methyl radical, symbols R.sup.5 and R.sup.8 stand each for a methyl radical, symbols R.sup.6 and R.sup.7 can be identical or different and designate each a hydrogen atom or a methyl radical and, either symbol R.sup.4 represents a methyl radical and symbol R.sup.3 stands for a hydrogen atom or a methyl radical, or symbols R.sup.3 and R.sup.4 represent each a methylene radical belonging to a ring such as indicated by the dotted line, with the proviso that the following combinations are excluded:1. R.sup.1 =R.sup.2 =R.sup.3 =R.sup.6 =R.sup.7 =H, or2. R.sup.1 =R.sup.2 =R.sup.3 =H and R.sup.6 or R.sup.7 =CH.sub.3, or3. R.sup.2 =CH.sub.3 and R.sup.3 =R.sup.6 =R.sup.7 =H, or4. R.sup.2 =CH.sub.3 and R.sup.3 =H and R.sup.6 or R.sup.7 =CH.sub.3, or5. R.sup.1 =R.sup.
    Type: Grant
    Filed: January 6, 1992
    Date of Patent: February 9, 1993
    Assignee: Firmenich S.A.
    Inventors: Charles Fehr, Jose Galindo
  • Patent number: 5162588
    Abstract: Compound of formula ##STR1## wherein a) indexes m and n are identical and stand each for an integer number equal to zero, symbols R.sup.1 and R.sup.2 are identical and represent each a hydrogen atom, or are different and represent each a hydrogen atom or a methyl radical, symbols R.sup.5 and R.sup.8 stand each for a methyl radical, symbols R.sup.6 and R.sup.7 can be identical or different and designate each a hydrogen atom or a methyl radical and, either symbol R.sup.4 represents a methyl radical and symbol R.sup.3 stands for a hydrogen atom or a methyl radical, or symbols R.sup.3 and R.sup.4 represent each a methylene radical belonging to a ring such as indicated by the dotted line, with the proviso that the following combinations are excluded:1. R.sup.1 =R.sup.2 =R.sup.3 =R.sup.6 =R.sup.7 =H, or2. R.sup.1 =R.sup.2 =R.sup.3 =H and R.sup.6 or R.sup.7 =CH.sub.3, or3. R.sup.2 =CH.sub.3 and R.sup.3 =R.sup.6 =R.sup.7 =H, or4. R.sup.2 =CH.sub.3 and R.sup.3 =H and R.sup.6 or R.sup.7 =CH.sub.3, or5. R.sup.1 =R.sup.
    Type: Grant
    Filed: June 26, 1990
    Date of Patent: November 10, 1992
    Assignee: Firmenich S.A.
    Inventors: Charles Fehr, Jose Galindo
  • Patent number: 5039659
    Abstract: Described are 2,2,3-trimethylcyclopentenyl acetone derivatives defined according to one or a mixture of compounds having the structures: ##STR1## organoleptic uses thereof, processes for preparing same using as a starting material the compound having the structure: ##STR2## which is reacted to form the compound having the structure: ##STR3## which is further reacted to form the novel intermediate: ##STR4## which is then converted to the 2,2,3-trimethylcyclopentenyl acetone derivatives or our invention using the allylic alcohol having the structure: ##STR5## wherein R.sub.3, R.sub.4, and R.sub.5 are the same or different hydrogen or methyl; R.sub.6 represents hydrogen, methyl, ethyl, or propyl or isopropyl; x is 0, 1 or 2; R.sub.7 is methyl or ethyl; R.sub.7 ' and R.sub.7 " represent methyl or ethyl or R.sub.7 ', (CH.sub.2).sub.x and R.sub.7 " taken together represents C.sub.2 -C.sub.6 alkylene; M represents Li, Mg, X or MgX; and X represents chloro or bromo.
    Type: Grant
    Filed: August 7, 1990
    Date of Patent: August 13, 1991
    Assignee: International Flavors & Fragrances Inc.
    Inventors: Anubhav P. S. Narula, John J. De Virgilio, Vincent F. Kuczinski, Anton V. Ouwerkerk, Charles E. J. Beck, Kathleen E. Boardwick, Marie R. Hanna
  • Patent number: 4992416
    Abstract: Isomeric formyl trimethylbicyclo[2.2.2]oct-7-enes, their use as perfumes, and a process for their preparation comprising a Diels-Alder reaction of acrolein with either 1,5,5-trimethylcyclohexa-1,3-diene, 3,5,5-trimethylcyclohexa-1,3-diene, 5,5-dimethyl-3-methylene-cyclohex-1-ene or mixtures thereof.
    Type: Grant
    Filed: May 5, 1989
    Date of Patent: February 12, 1991
    Assignee: Henkel Kommanditgesellschaft auf Aktien
    Inventors: Klaus Bruns, Thomas Gerke, Michael Virnig
  • Patent number: 4902840
    Abstract: Described are substituted tetrahydroindanes defined according to the generic structure: ##STR1## wherein Z is a moiety selected from the group consisting of: ##STR2## wherein X represents chloro or bromo; wherein R.sub.1 represents:--OR.sub.3 or --O.sup..sym. M.sup..crclbar. ;wherein R.sub.3 represents hydrogen, methyl or ethyl; wherein M represents alkali metal, sodium potassium or lithium; wherein R.sub.2 represents hydrogen or the moiety: ##STR3## as well as uses of substituted tetrahydroindanes defined according to the structure: ##STR4## wherein Z' represents a moiety selected from the group consisting of: ##STR5## wherein R.sub.2 is hydrogen and wherein R.sub.1 is the moiety:OR.sub.3 'wherein R.sub.
    Type: Grant
    Filed: April 28, 1989
    Date of Patent: February 20, 1990
    Assignee: International Flavors and Fragrances Inc.
    Inventors: Mark A. Sprecker, Robert P. Belko, Charles E. J. Beck
  • Patent number: 4885274
    Abstract: The perfume composition containing 4- (or 5-)-acyl-1,1- (or 3,3-)-[a] compound, which is a novel compound expressed by the formula I, has noble musk fragrance. In addition, this perfume composition has characteristics that it is excellent in both quality and strength of the fragrance, of high safety and capable of being manufactured with low costs.
    Type: Grant
    Filed: November 23, 1987
    Date of Patent: December 5, 1989
    Assignee: Takasago Perfumery Co., Ltd.
    Inventors: Nobuo Yamada, Toyohiko Kobayashi