Carbonyl Bonded Directly To The Ring System Patents (Class 512/16)
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Patent number: 11866403Abstract: The present invention provides a carboxylic acid ester compound represented by formula (1) that is useful as a fragrance component or as a formulated fragrance material, wherein R1 is —COOR, wherein R is an alkyl group having 1 to 4 carbon atoms.Type: GrantFiled: May 28, 2019Date of Patent: January 9, 2024Assignee: Mitsubishi Gas Chemical Company, Inc.Inventors: Yutaka Matsuura, Tomohiko Hakamata
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Patent number: 9834738Abstract: The present invention is directed to a novel fragrance compound of octahydro-4,7-methano-1H-indene-5-acetaldehyde.Type: GrantFiled: December 13, 2013Date of Patent: December 5, 2017Inventors: Anubhav P. S. Narula, James Anthony Lasome, Richard A. Weiss, Michael G. Monteleone
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Publication number: 20150005214Abstract: The present invention concerns compounds of formula (I) in the form of any one of its stereoisomers or a mixture thereof, and wherein one dotted line represents a carbon-carbon single or double bond and the others a carbon-carbon single bond; each R, independently from each other, represents a hydrogen atom or a methyl or ethyl group provided that at least one of said R groups represents a methyl or ethyl group; and R1 represents a methyl or ethyl group; and their use in perfumery to impart odor notes of the woody type having cedar, ambery, patchouli and/or rooty aspect.Type: ApplicationFiled: December 20, 2012Publication date: January 1, 2015Inventor: Anthony A. Birkbeck
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Patent number: 8877704Abstract: Disclosed are certain compounds according to the general formula (I) and their use as flavoring and fragrancing compounds, as well as fragranced and flavored compositions comprising the compounds of formula (I), and methods for providing a flavor or fragrance to compositions and articles utilizing the compounds of formula (I).Type: GrantFiled: October 11, 2013Date of Patent: November 4, 2014Assignee: Givaudan SAInventors: Jean-Pierre Bachmann, Felix Flachsmann
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Patent number: 8022030Abstract: The present invention relates to the field of perfumery. More particularly, it concerns co-polymers, derived from a maleic anhydride derivative and a ethylenic derivative, comprising at least one ?-oxy or ?-thio carbonyl moiety capable of liberating an active molecule such as, for example, an ?,?-unsaturated ketone, aldehyde or carboxylic ester. The present invention concerns also the use of polymers or co-polymers in perfumery as well as the perfuming compositions or perfumed articles comprising the invention's compounds.Type: GrantFiled: October 5, 2007Date of Patent: September 20, 2011Assignee: Firmenich SAInventors: Damien Berthier, Andreas Herrmann
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Publication number: 20110182832Abstract: Perfume ingredients have been investigated and classified for their effectiveness in detaching biofilms from surfaces. Based on this classification, perfume compositions that are effective in assisting biofilm detachment can be formulated, whilst also allowing a degree of freedom in formulation that permits consideration of the hedonic properties of the composition. The compositions can be used in a wide range of perfumed consumer products, such as personal, domestic and industrial products, e.g. hard surface cleaning products, dental care products, and deodorant products.Type: ApplicationFiled: April 13, 2006Publication date: July 28, 2011Applicant: QUEST INTERNATIONAL SERVICES B.V.Inventors: David Jonathan Bradshaw, Alan Forbes Provan, Christopher James Ioannou, John Martin Behan, Keith Douglas Perring
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Patent number: 7888309Abstract: This invention relates to substituted cyclooctenes of the formula I, wherein X and R are defined in the specification.Type: GrantFiled: September 1, 2009Date of Patent: February 15, 2011Assignee: Givaudan SAInventors: Thierry Granier, Jerzy A. Bajgrowicz, Andreas Hanhart
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Patent number: 7691802Abstract: Novel compounds of formula I and their use in flavour and fragrance compositions. R1 to R13 have the meaning as described in the specification.Type: GrantFiled: June 20, 2003Date of Patent: April 6, 2010Assignee: Givaudan SAInventor: Andreas Goeke
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Patent number: 7648955Abstract: A fragrance composition is provided comprising from about 10% wt to about 40% wt of a residual accord, the residual accord comprising perfume raw materials (PRMs) selected from at least three of the five defined classes. In addition, personal care compositions comprising the defined fragrance composition are also provided.Type: GrantFiled: November 4, 2004Date of Patent: January 19, 2010Assignee: The Procter & Gamble CompanyInventors: Zerlina Guzdar Dubois, Lynette Anne Makins Holland
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Patent number: 7378383Abstract: The present invention relates to the use as perfuming ingredient of a decaline derivative of formula wherein R1 is a lower alkyl, the R2 to R5 are hydrogen atoms or lower alkyls and at least one dotted line is a double bond, which is a useful perfuming ingredient of the woody or woody-citrus type.Type: GrantFiled: May 6, 2005Date of Patent: May 27, 2008Assignee: Firmenich SAInventors: Robert Moretti, Olivier Etter
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Patent number: 7312187Abstract: Described are polyalkylbicylic chemical derivatives for use a fragrance ingredients having the generic structure: wherein m=0 or 1; wherein X is methyl or hydrogen; wherein R1, R2, R3 and R4 each represents methyl or ethyl with the proviso that when X is methyl, each of R1, R2, R3 and R4 is methyl and when X is hydrogen, one of R1, R2, R3 and R4 is ethyl; and wherein R6 represents hydrogen or methyl. Methods for using and making these compounds are also disclosed.Type: GrantFiled: September 26, 2003Date of Patent: December 25, 2007Assignee: International Flavors & Fragrances Inc.Inventors: Anubhav P. S. Narula, Edward Mark Arruda
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Patent number: 7256170Abstract: The present invention relates to the perfumery industry. It concerns more particularly an alcohol, ester, ether or ketone derivative having a spiro-type skeleton, the latter being substituted by short alkyl groups. The invention also relates to the use of the invention compounds as perfuming ingredients, able to impart a woody and/or aromatic, as well as to the perfumed articles or perfuming compositions comprising as active ingredient a compound of formula (I).Type: GrantFiled: October 8, 2003Date of Patent: August 14, 2007Assignee: Firmenich SAInventors: Christian Vial, Robert Moretti, Alain Charpilloz, Peter Fankhauser, Piero Fantini
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Patent number: 7160852Abstract: The compound according to the formula set forth below and the use of the compound in creating fragrances, and scents in items such as perfumes, colognes and personal care products is disclosed.Type: GrantFiled: August 7, 2003Date of Patent: January 9, 2007Assignee: International Flavors & Fragrances IncInventors: Anthony T. Levorse, Jr., Anubhav P. S. Narula, Edward Mark Arruda, Charles E. J. Beck
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Patent number: 6958395Abstract: The present invention relates to a method by which saccharide compounds can be prepared in a very easy way. This method comprises the steps of: (a) attaching at least one saccharide to a cyclic or acyclic diene, (b) reacting the saccharide-containing diene obtained in step (a) or a commercially available saccharide-containing diene with a dienophile by Diels-Alder reaction.Type: GrantFiled: August 22, 2001Date of Patent: October 25, 2005Assignee: Deutsches Krebsforschungszentrum Stiftung des Offentlichen RechtsInventors: Manfred Wiessler, Hans-Christian Kliem, Bernd Sauerbrei, Birgit Schmauser
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Patent number: 6949680Abstract: A compound of formula wherein Y represents a pyridyl group, or a phenyl group of formula wherein R3 represents a hydrogen atom, a CF3 group or an alkoxy group, R4 represents a hydrogen atom, an alkyl group, or a CF3 group, R5 represents a hydrogen atom, an alkyl group, a CF3 group or an alkoxy group, and R1 and R2 are the substituents of a terminal alkene of formula wherein R1 represents an alkyl or alkylene group, a mono- or poly-cycloalkyl group, or a phenyl group that optionally includes one or several hetero-atoms of oxygen, nitrogen, phosphorous or sulfur; R2 represents a hydrogen atom, an alkyl or alkylene group, a mono- or poly-cycloalkyl group, or a phenyl group that optionally includes one or several hetero-atoms of oxygen, nitrogen, phosphorous and sulfur.Type: GrantFiled: October 15, 2002Date of Patent: September 27, 2005Assignee: Firmenich SAInventor: Andreas Herrmann
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Publication number: 20040186043Abstract: The present invention relates to the field of perfumery, and more precisely to a compound of formula (I) 1Type: ApplicationFiled: March 2, 2004Publication date: September 23, 2004Inventor: Alvin Scott Williams
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Patent number: 6632788Abstract: The compound according to the formula set forth below where A is B is or A and B together form the ring structure and X, R′ and R are independently H and CH3 and m=0 or 1. and the use of the compound in creating fragrances, and scents in items such as perfumes, colognes and personal care products is disclosed.Type: GrantFiled: May 17, 2001Date of Patent: October 14, 2003Assignee: International Flavors & Fragrances Inc.Inventors: Anthony T. Levorse, Jr., Anubhav P.S. Narula, Edward Mark Arruda, Charles E.J. Beck
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Patent number: 6239314Abstract: The invention relates to compounds of the general formula in which R1 to R7 are, independently, H, methyl or ethyl, R8+R9 together form methylene (—CH2—) or a single bond, or R1+R2 together form —(CH2)n—, with n being 3 or 4, or R3+R5 or R5+R7 represent methylene or a single bond; and the presence of at least one cyclopropane ring in the molecule is compulsory and the side chain can be saturated or contains one double bond in position &agr;,&bgr; or &bgr;,&ggr;, a process for the manufacture of these compounds, compounds used to perform the process and the use of these compounds as an odorant or as an ingredient of an odorant composition.Type: GrantFiled: October 5, 2000Date of Patent: May 29, 2001Assignee: Givaudan Roure (International) SAInventors: Jerzy A. Bajgrowicz, Georg Frater
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Patent number: 6211153Abstract: Methods for treating prostate cancer are disclosed. The methods of the invention generally feature administration to a subject of an LHRH-R antagonist, in combination with a second therapy. In one embodiment, this second therapy is performance of a procedure that removes or destroys prostatic tumor tissue, such as a radical prostatectomy, cryosurgery or X-ray therapy (external or interstitial). In another embodiment, the second therapy is treatment with an LHRH-R agonist, either simultaneous with or subsequent to LHRH-R antagonist therapy. The methods of the invention can further involve administering an antiandrogen and/or an inhibitor of sex steroid biosynthesis to the subject in combination with the LHRH-R antagonist.Type: GrantFiled: November 11, 1999Date of Patent: April 3, 2001Assignee: Praecis Pharmaceuticals, Inc.Inventors: Marc B. Garnick, Christopher J. Molineaux, Malcolm L. Gefter
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Patent number: 5492887Abstract: It was found that 8-exo-formyl-2,6-exo-tricyclo[5.2.1.0.sup.2,6 ]decane having the constitution and stereochemistry of formula (I) possesses particularly useful olfactory properties which are clearly superior to those of the 8-endo-epimer and which already have an effect if compound (I) is enriched with mixtures of 8-exo- and 8-endo-epimers. Compound (I) can therefore be advantageously used, in pure or enriched form, as a scent or as a component of perfume compositions. To prepare an enriched epimer mixture, a mixture obtained in a known manner (U.S. Pat. No. 3,270,061) and having an exo/endo ratio of 1.45:1 is brought into equilibrium by base catalysis, preferably by the action of alkali hydroxides in alcoholic solution, to give an exo/endo ratio of 5.25:1. Alternatively, the enriched epimer mixture can be prepared starting from 8-formyl-2,6-exo-tricyclo[5.2.1.0.sup.2,6 ]decene-3(4), catalytically hydrogenated for example with palladium coal and then optionally brought into equilibrium.Type: GrantFiled: December 11, 1992Date of Patent: February 20, 1996Assignee: Dragoco Gerberding & Co. GmbHInventors: Ernst-Joachim Brunke, Claus-Hermann Kappey, Bernd Holscher, Hartmut Struwe
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Patent number: 5401720Abstract: The present invention relates, inter alia, to novel alkyl tetralin aldehyde compounds having fragrant musk-like aroma.Type: GrantFiled: January 21, 1994Date of Patent: March 28, 1995Assignee: Union Camp CorporationInventor: Walter C. Frank
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Patent number: 5185318Abstract: Compound of formula ##STR1## wherein a) indexes m and n are identical and stand each for an integer number equal to zero, symbols R.sup.1 and R.sup.2 are identical and represent each a hydrogen atom, or are different and represent each a hydrogen atom or a methyl radical, symbols R.sup.5 and R.sup.8 stand each for a methyl radical, symbols R.sup.6 and R.sup.7 can be identical or different and designate each a hydrogen atom or a methyl radical and, either symbol R.sup.4 represents a methyl radical and symbol R.sup.3 stands for a hydrogen atom or a methyl radical, or symbols R.sup.3 and R.sup.4 represent each a methylene radical belonging to a ring such as indicated by the dotted line, with the proviso that the following combinations are excluded:1. R.sup.1 =R.sup.2 =R.sup.3 =R.sup.6 =R.sup.7 =H, or2. R.sup.1 =R.sup.2 =R.sup.3 =H and R.sup.6 or R.sup.7 =CH.sub.3, or3. R.sup.2 =CH.sub.3 and R.sup.3 =R.sup.6 =R.sup.7 =H, or4. R.sup.2 =CH.sub.3 and R.sup.3 =H and R.sup.6 or R.sup.7 =CH.sub.3, or5. R.sup.1 =R.sup.Type: GrantFiled: January 6, 1992Date of Patent: February 9, 1993Assignee: Firmenich S.A.Inventors: Charles Fehr, Jose Galindo
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Patent number: 5162588Abstract: Compound of formula ##STR1## wherein a) indexes m and n are identical and stand each for an integer number equal to zero, symbols R.sup.1 and R.sup.2 are identical and represent each a hydrogen atom, or are different and represent each a hydrogen atom or a methyl radical, symbols R.sup.5 and R.sup.8 stand each for a methyl radical, symbols R.sup.6 and R.sup.7 can be identical or different and designate each a hydrogen atom or a methyl radical and, either symbol R.sup.4 represents a methyl radical and symbol R.sup.3 stands for a hydrogen atom or a methyl radical, or symbols R.sup.3 and R.sup.4 represent each a methylene radical belonging to a ring such as indicated by the dotted line, with the proviso that the following combinations are excluded:1. R.sup.1 =R.sup.2 =R.sup.3 =R.sup.6 =R.sup.7 =H, or2. R.sup.1 =R.sup.2 =R.sup.3 =H and R.sup.6 or R.sup.7 =CH.sub.3, or3. R.sup.2 =CH.sub.3 and R.sup.3 =R.sup.6 =R.sup.7 =H, or4. R.sup.2 =CH.sub.3 and R.sup.3 =H and R.sup.6 or R.sup.7 =CH.sub.3, or5. R.sup.1 =R.sup.Type: GrantFiled: June 26, 1990Date of Patent: November 10, 1992Assignee: Firmenich S.A.Inventors: Charles Fehr, Jose Galindo
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Patent number: 5039659Abstract: Described are 2,2,3-trimethylcyclopentenyl acetone derivatives defined according to one or a mixture of compounds having the structures: ##STR1## organoleptic uses thereof, processes for preparing same using as a starting material the compound having the structure: ##STR2## which is reacted to form the compound having the structure: ##STR3## which is further reacted to form the novel intermediate: ##STR4## which is then converted to the 2,2,3-trimethylcyclopentenyl acetone derivatives or our invention using the allylic alcohol having the structure: ##STR5## wherein R.sub.3, R.sub.4, and R.sub.5 are the same or different hydrogen or methyl; R.sub.6 represents hydrogen, methyl, ethyl, or propyl or isopropyl; x is 0, 1 or 2; R.sub.7 is methyl or ethyl; R.sub.7 ' and R.sub.7 " represent methyl or ethyl or R.sub.7 ', (CH.sub.2).sub.x and R.sub.7 " taken together represents C.sub.2 -C.sub.6 alkylene; M represents Li, Mg, X or MgX; and X represents chloro or bromo.Type: GrantFiled: August 7, 1990Date of Patent: August 13, 1991Assignee: International Flavors & Fragrances Inc.Inventors: Anubhav P. S. Narula, John J. De Virgilio, Vincent F. Kuczinski, Anton V. Ouwerkerk, Charles E. J. Beck, Kathleen E. Boardwick, Marie R. Hanna
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Patent number: 4992416Abstract: Isomeric formyl trimethylbicyclo[2.2.2]oct-7-enes, their use as perfumes, and a process for their preparation comprising a Diels-Alder reaction of acrolein with either 1,5,5-trimethylcyclohexa-1,3-diene, 3,5,5-trimethylcyclohexa-1,3-diene, 5,5-dimethyl-3-methylene-cyclohex-1-ene or mixtures thereof.Type: GrantFiled: May 5, 1989Date of Patent: February 12, 1991Assignee: Henkel Kommanditgesellschaft auf AktienInventors: Klaus Bruns, Thomas Gerke, Michael Virnig
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Patent number: 4902840Abstract: Described are substituted tetrahydroindanes defined according to the generic structure: ##STR1## wherein Z is a moiety selected from the group consisting of: ##STR2## wherein X represents chloro or bromo; wherein R.sub.1 represents:--OR.sub.3 or --O.sup..sym. M.sup..crclbar. ;wherein R.sub.3 represents hydrogen, methyl or ethyl; wherein M represents alkali metal, sodium potassium or lithium; wherein R.sub.2 represents hydrogen or the moiety: ##STR3## as well as uses of substituted tetrahydroindanes defined according to the structure: ##STR4## wherein Z' represents a moiety selected from the group consisting of: ##STR5## wherein R.sub.2 is hydrogen and wherein R.sub.1 is the moiety:OR.sub.3 'wherein R.sub.Type: GrantFiled: April 28, 1989Date of Patent: February 20, 1990Assignee: International Flavors and Fragrances Inc.Inventors: Mark A. Sprecker, Robert P. Belko, Charles E. J. Beck
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Patent number: 4885274Abstract: The perfume composition containing 4- (or 5-)-acyl-1,1- (or 3,3-)-[a] compound, which is a novel compound expressed by the formula I, has noble musk fragrance. In addition, this perfume composition has characteristics that it is excellent in both quality and strength of the fragrance, of high safety and capable of being manufactured with low costs.Type: GrantFiled: November 23, 1987Date of Patent: December 5, 1989Assignee: Takasago Perfumery Co., Ltd.Inventors: Nobuo Yamada, Toyohiko Kobayashi