With Organic Oxygen Containing Compound Patents (Class 514/164)
-
Publication number: 20100099642Abstract: The invention relates to the use of TGF-beta stimulating agents, and in particular members of the triphenylethylene class of pharmaceutical agents, for the prevention, prophylaxis, treatment or amelioration of symptoms of cardiovascular disease, autoimmune diseases or neurodegeneration. In particular, improved compositions consisting of triphenylethylene agents combined with one or more additional active pharmaceutical agents in order to mitigate against side-effects of the triphenylethylene are described and claimed.Type: ApplicationFiled: February 7, 2008Publication date: April 22, 2010Applicant: TCP Innovations LimitedInventor: David J. Grainger
-
Patent number: 7700081Abstract: The invention concerns a foaming composition for washing and treating hair and/or scalp essentially characterised in that it contains in an aqueous medium: at least an active principle selected among corticoids and retinoids; at least an anionic surfactant; at least an amphoteric surfactant; and a pro-penetrating agent.Type: GrantFiled: June 16, 2006Date of Patent: April 20, 2010Assignee: Galderma S.A.Inventors: Isabelle Preuilh, Anne-Emmanuelle Guise, Nathalie Willcox
-
Publication number: 20100087403Abstract: The invention relates to an unexpected discovery that propylene glycol is highly effective at killing or inhibiting Propionibacterium acnes in a mammalian skin disorder, as well as to the use of propylene glycol and salicylic acid in a skin-disorder treatment. This invention also relates to compositions containing propylene glycol alone or in combination with salicylic acid for use in killing or inhibiting Propionibacterium acnes.Type: ApplicationFiled: October 3, 2008Publication date: April 8, 2010Inventor: WIN L. CHIOU
-
Patent number: 7691832Abstract: Inflammatory bowel diseases are represented by two idiopathic disorders, which include ulcerative colitis and Crohn's disease. Ulcerative colitis is restricted to the colon and involves uncertain and inflammation of the lining (mucosa) of the large intestine. Crohn's disease, on the other hand, can involve the mucosa of the small and/or large intestine and may involve deeper layers of the bowel wall. The present invention contains N-acetylcysteine disposed in a pharmaceutically acceptable carrier for oral or rectal delivery for treating such inflammatory bowel diseases by topical application within the colon.Type: GrantFiled: February 2, 2006Date of Patent: April 6, 2010Assignee: The Board of Regents of the University of OklahomaInventor: Richard F. Harty
-
Patent number: 7638507Abstract: Inflammatory bowel diseases are represented by two idiopathic disorders, which include ulcerative colitis and Crohn's disease. Ulcerative colitis is restricted to the colon and involves uncertain and inflammation of the lining (mucosa) of the large intestine. Crohn's disease, on the other hand, can involve the mucosa of the small and/or large intestine and may involve deeper layers of the bowel wall. The present invention is a combination of 5-aminosalicylic acid and one or more antioxidants (e.g., N-acetylcysteine) for treating such inflammatory bowel diseases.Type: GrantFiled: February 2, 2006Date of Patent: December 29, 2009Assignee: The Board of Regents of the University of OklahomaInventor: Richard F. Harty
-
Publication number: 20090202457Abstract: The present invention relates to an exfoliating composition. The composition comprises a mixture. The mixture comprises phenolsulfonic acid, guaiacolsulfonic acid, and optionally sulfosalicylic acid and citric acid.Type: ApplicationFiled: March 9, 2009Publication date: August 13, 2009Inventor: Michael Basara
-
Publication number: 20090163530Abstract: Physiologically acceptable films, including edible films, are disclosed. The films include a water soluble film-forming polymer such as pullulan. Edible films are disclosed that include pullulan and antimicrobially effective amounts of the essential oils thymol, methyl salicylate, eucalyptol and menthol. The edible films are effective at killing the plaque-producing germs that cause dental plaque, gingivitis and bad breath. The film can also contain pharmaceutically active agents. Methods for producing the films are also disclosed.Type: ApplicationFiled: June 3, 2008Publication date: June 25, 2009Inventors: Sau-Hung Spence Leung, Robert S. Leone, Lori D. Kumar, Neema Kulkarni, Albert F. Sorg
-
Publication number: 20090123577Abstract: The invention relates to a liquid concentrate for preserving cosmetic products which comprises a combination of carboxylic acid salts chosen from the salts of benzoic acid, propionic acid, salicylic acid, sorbic acid, 4-hydroxybenzoic acid, dehydracetic acid, formic acid or 10-undecylenic acid and alcohols chosen from 2-phenoxyethanol, benzyl alcohol, phenethyl alcohol, 1-phenoxypropan-2-ol, 3-(4-chlorophenoxy)-1,2-propanediol, chlorobutanol or 2,4-dichlorobenzyl alcohol in a solvent, where the active ingredient content is greater than 45% by weight.Type: ApplicationFiled: January 13, 2009Publication date: May 14, 2009Applicant: AIR LIQUIDE SANTE (INTERNATIONAL)Inventors: Wolfgang BEILFUSS, Gisela Hahn, Klaus Weber, Ralf Gradke
-
Publication number: 20090035392Abstract: Methods, apparatus, systems and the like for treating acne vulgaris that improves treatment effectiveness and/or reduces bothersome side effects associated with the ingredients used. The present Methods, apparatus, systems, etc., also provide topical compositions of benzoyl peroxide and/or other anti-acne agents that are useful for treating acne vulgaris and may be used simultaneously or sequentially in a user-adjustable ratio of two or more such compositions, or other compositions as desired such as cleansers or lotions.Type: ApplicationFiled: June 9, 2006Publication date: February 5, 2009Inventor: Randall Wilkinson
-
Patent number: 7417037Abstract: Inflammatory bowel diseases are represented by two idiopathic disorders, which include ulcerative colitis and Crohn's disease. Ulcerative colitis is restricted to the colon and involves uncertain and inflammation of the lining (mucosa) of the large intestine. Crohn's disease, on the other hand, can involve the mucosa of the small and/or large intestine and may involve deeper layers of the bowel wall. The present invention is a combination of 5-aminosalicylic acid and one or more antioxidants (e.g., N-acetylcysteine) for treating such inflammatory bowel diseases.Type: GrantFiled: December 28, 2004Date of Patent: August 26, 2008Assignee: The Board of Regents of the University of OklahomaInventor: Richard F. Harty
-
Publication number: 20080161275Abstract: The invention relates to methods of treating inflammatory disease comprising administering a compound of formula A, a compound of any one of formulae 1-49, a lipoxin compound, or an oxylipin compound.Type: ApplicationFiled: December 5, 2007Publication date: July 3, 2008Applicant: Resolvyx Pharmaceuticals, Inc.Inventor: Per Gjorstrup
-
Publication number: 20080139518Abstract: The invention provides a topical formulation adapted for treatment of a skin condition comprising (i) at least one retinoid; and (ii) salicylic acid or an ester, amide, salt, or solvate thereof. The invention also includes a kit for treatment of skin conditions comprising a retinoid and salicylic acid, as well as a method of treating skin conditions utilizing the inventive formulation and kit.Type: ApplicationFiled: December 4, 2007Publication date: June 12, 2008Inventor: William Paul Purcell
-
Publication number: 20080124280Abstract: Disclosed are methods of treating subjects having conditions related to angiogenesis including administering an effective amount of a polymeric form of thyroid hormone, or an antagonist thereof, to promote or inhibit angiogenesis in the subject. Compositions of the polymeric forms of thyroid hormone, or thyroid hormone analogs, are also disclosed.Type: ApplicationFiled: September 15, 2005Publication date: May 29, 2008Inventors: Shaker A. Mousa, Faith B. Davis, Paul J. Davis
-
Patent number: 7323452Abstract: A method for accelerating the process of removing ethanol from the blood through the use of certain additives that accelerate the metabolic oxidation of ethanol, and others which in addition act as catalysts or “pseudo” enzymes for the oxidation. These additives include multivalent transition metal ions, as well as complexes thereof, and NAD+ which enhance the oxidation reaction. The method described can act as a sobriety inducer and/or as an effective palliative for the unpleasant effects of overuse of ethanol.Type: GrantFiled: December 20, 2004Date of Patent: January 29, 2008Assignee: Wardan, L.L.C.Inventors: Ward B. Bowen, Jr., Daniel S. Daniel
-
Patent number: 7316810Abstract: The invention concerns a foaming composition for washing and treating hair and/or scalp essentially characterized in that it contains in an aqueous medium: at least an active principle selected among corticoids and retinoids; at least an anionic surfactant; at least an amphoteric surfactant; and a pro-penetrating agent.Type: GrantFiled: November 13, 2000Date of Patent: January 8, 2008Assignee: Galderma S.A.Inventors: Isabelle Preuilh, Anne-Emmanuelle Guise, Nathalie Willcox
-
Patent number: 7141611Abstract: This invention provides an isolated mixture of higher molecular weight primary aliphatic alcohols having 20, 22, 24, 26, 27, 28, 30, 32 and 34 carbon atoms and having enhanced purity. This invention also provides a process for obtaining the alcohol mixture by extracting a natural product with organic solvents with or without saponification of the natural product. The alcohol mixture is useful in pharmaceutical compositions, foodstuffs and dietary supplements and is effective for lowering total cholesterol and LDL-cholesterol and increasing HDL-cholesterol levels and therefore is effective in treating hypercholesterolemia. The composition may be used to reduce the risk of coronary heart disease, to inhibit the atherosclerotic process (platelet hyperaggregability, ischemia and thrombosis), and can be used as an anti-inflammatory and anti-thrombotic agent. The composition also possesses neurotrophic properties and is useful for improving male sexual activity.Type: GrantFiled: July 18, 2003Date of Patent: November 28, 2006Assignee: WyethInventors: William R. Gamble, Zhengjie Liu, David T. Bailey, Pedro P. Perez, Dean P. Stull, Steven L. Richheimer, Rebecca L. Nichols, Rod Lenoble
-
Patent number: 7135197Abstract: The present invention provides a pharmaceutical composition comprising at least one pharmaceutically acceptable bismuth-containing compound, at least one pharmaceutically acceptable non-clay-derived suspending agent, and water. The suspension exhibits reduced upward pH drift by comparison with an otherwise similar suspension which comprises a clay-derived suspending agent. Such compositions are useful in the prevention and treatment of gastrointestinal diseases and/or disorders.Type: GrantFiled: February 3, 2003Date of Patent: November 14, 2006Assignee: Pharmacia CorporationInventors: Lorraine E. Pena, Dennis L. Huczek
-
Patent number: 7094431Abstract: This invention pertains to therapeutic antibacterial/antifungal-wound healing compositions comprising a therapeutically effective amount of antibacterial agents and/or antifungal agents and/or wound healing composition alone. In one embodiment, the wound healing composition comprises (a) zinc oxide; (b) calcium channel blocker, and (c) fat-soluble vitamins admixed with antibacterial and antifungal agents. The therapeutic antibacterial/antifungal-wound healing compositions may be utilized in a wide variety of pharmaceutical products and administered orally or topically.Type: GrantFiled: September 30, 2003Date of Patent: August 22, 2006Inventor: Mickey L. Peshoff
-
Patent number: 7034060Abstract: The present invention provides a novel method for the preparation of a unique profile of primary aliphatic alcohols, having 24 to 30 carbon atoms, from the wax secreted by the insect Ericerus pela. Included in the present invention is the composition of matter, referred to herein as “polycosanol” produced by the method of this invention. The polycosanol composition is comprised primarily of the four primary aliphatic alcohols, tetracosanol, hexacosanol, octacosanol and triacontanol. Further included in this invention is the use of said composition of matter for the prevention and treatment of obesity, syndrome X, diabetes, hypercholesterolemia, atherosclerotic complications, ischemia and thrombosis.Type: GrantFiled: November 16, 2004Date of Patent: April 25, 2006Assignee: Unigen Pharmaceuticals, Inc.Inventors: Qi Jia, Ji-Fu Zhao
-
Patent number: 7029706Abstract: The inventions relates to the use of silica in the formulation of antifungal composition for the treatment of cutaneous mycoses, and method to manufacture an antifungal powder with boric acid and silica.Type: GrantFiled: November 21, 2002Date of Patent: April 18, 2006Inventor: Carlos Alberto Marrodan
-
Patent number: 6984666Abstract: The present invention provides a novel method for the preparation of a unique profile of primary aliphatic alcohols, having 24 to 30 carbon atoms, from the wax secreted by the insect Ericerus pela. Included in the present invention is the composition of matter, referred to herein as “polycosanol” produced by the method of this invention. The polycosanol composition is comprised primarily of the four primary aliphatic alcohols, tetracosanol, hexacosanol, octacosanol and triacontanol. Further included in this invention is the use of said composition of matter for the prevention and treatment of obesity, syndrome X, diabetes, hypercholesterolemia, atherosclerotic complications, ischemia and thrombosis.Type: GrantFiled: November 16, 2004Date of Patent: January 10, 2006Assignee: Unigen Pharmaceuticals, Inc.Inventors: Qi Jia, Ji-Fu Zhao
-
Patent number: 6974584Abstract: Pesticidal compositions for the control of human body louse containing one or more plant essential oils. In addition, the present invention is directed to a method for controlling human body louse by applying a pesticidally-effective amount of the above pesticidal compositions to a locus where pest control is desired.Type: GrantFiled: October 15, 2002Date of Patent: December 13, 2005Assignee: Ecosmart Technologies, Inc.Inventor: Steven M. Bessette
-
Patent number: 6964782Abstract: Disclosed are several preferred embodiments of hydrogen peroxide which are packaged with ease of use and extended shelf-life in mind. The embodiments include foam, mist, gel, and disposable towelette forms of H2O2. Optional ingredients of topical pain relievers and skin protectants are also disclosed, as are their methods of use.Type: GrantFiled: July 7, 2003Date of Patent: November 15, 2005Assignee: Tec Labs, Inc.Inventors: Robert Lee Smith, Steven Dale Smith, Wendy S. Langley, John Mark Christensen, Vernon W. Smith
-
Patent number: 6855341Abstract: Disclosed are anti-viral compositions containing at least one zinc compound and at least one phenolic antioxidant (and optionally other ingredients), and a pharmaceutical carrier. Also disclosed are methods of treating lesionous symptoms of a viral infection involving applying an effective amount of the anti-viral composition to the lesions.Type: GrantFiled: November 4, 2002Date of Patent: February 15, 2005Inventor: Jeffrey B. Smith
-
Patent number: 6846837Abstract: Methods and topical pharmaceutical formulations are provided for the treatment of nail fungus (onychomycosis). The invention involves a pharmacologically active antifungal agent, plus a pharmaceutically acceptable base in a formulation having a pH of 7.5 to about 13.0, preferably about 8.0 to 11.5, and most preferably about 8.5 to 10.5. These basic formulations permeate the nail and are effective in treating fungal infections of the nail and surrounding tissues.Type: GrantFiled: June 21, 2002Date of Patent: January 25, 2005Inventors: Howard I. Maibach, Eric C. Luo, Tsung-Min Hsu
-
Patent number: 6833362Abstract: A composition for accelerating the disposal of ethanol from bodily fluid. Certain additives can accelerate the metabolic oxidation of ethanol, and others in addition act as catalysts or “pseudo” enzymes for the oxidation. Additives include the oxidant Nicotinamide Adenine Dinucleotide and a variety of other additives such as transition metal ions and complexes thereof which favor the oxidation reaction. The compositions described can act as a sobriety inducer and/or as an effective palliative for the unpleasant effects of overuse of ethanol.Type: GrantFiled: June 7, 2001Date of Patent: December 21, 2004Inventors: Ward Beryl Bowen, Jr., Daniel Salman Daniel
-
Patent number: 6822004Abstract: The present invention provides a novel method for the preparation of a unique profile of primary aliphatic alcohols having 24 to 30 carbon atoms, from the wax secreted by the insect Ericerus pela. Included in the present invention is the composition of matter, referred to herein as “polycosanol” produced by the method of this invention. The polycosanol composition is comprised primarily of the four primary aliphatic alcohols, tetracosanol, hexacosanol, octacosanol and triacontanol. Further included in this invention is the use of said composition of matter for the prevention and treatment of obesity, syndrome X, diabetes, hypercholesterolemia, atherosclerotic complications, ischemia and thrombosis.Type: GrantFiled: September 9, 2003Date of Patent: November 23, 2004Assignee: UniGen Pharmaceuticals, Inc.Inventors: Qi Jia, Ji-Fu Zhao
-
Patent number: 6783767Abstract: A powder composition which reacts in water to form in situ peroxycarboxylic acids at an anti-microbially effective concentration. Importantly, its utility is both for topical anti-microbial application and for effective low temperature disinfection/sterilization of instruments. It comprises the combination of a perborate, one or more novel acyl and/or aroyl donors, a buffering system which allows the pH to arise to about 9 for rapid formation of the peroxycarboxylic acids and then drop to about 7.5 for sustained stability and microbial kill. It preferably includes a surfactant facilitating antimicrobial efficacy, as well as other minors.Type: GrantFiled: February 8, 2002Date of Patent: August 31, 2004Assignee: Healthpoint, Ltd.Inventors: Braham Shroot, Lawton A. Seal, James R. Hunt, Jonathan Sterling, Kathy Bolsen, Penny L. Sitka
-
Patent number: 6730329Abstract: One aspect of the invention relates to anti-viral composition containing at least one zinc compound and at least one phenolic antioxidant (and optionally other ingredients such as at least one analgesic) at least one hydrocarbyl containing compound, and water. Another aspect of the invention relates to a method of treating lesionous symptoms of a viral infection involving applying an effective amount of the zinc containing anti-viral composition to the lesions.Type: GrantFiled: February 26, 2002Date of Patent: May 4, 2004Inventor: Jeffrey B. Smith
-
Patent number: 6683116Abstract: The present invention provides a novel method for the preparation of a unique profile of primary aliphatic alcohols, having 24 to 30 carbon atoms, from the wax secreted by the insect Ericerus pela. Included in the present invention is the composition of matter, referred to herein as “polycosanol” produced by the method of this invention. The polycosanol composition is comprised primarily of the four primary aliphatic alcohols, tetracosanol, hexacosanol, octacosanol and triacontanol. Further included in this invention is the use of said composition of matter for the prevention and treatment of obesity, syndrome X, diabetes, hypercholesterolemia, atherosclerotic complications, ischemia and thrombosis.Type: GrantFiled: January 31, 2003Date of Patent: January 27, 2004Assignee: Unigen Pharmaceuticals, Inc.Inventors: Qi Jia, Ji-Fu Zhao
-
Publication number: 20030215533Abstract: A method is presented for prevention of various respiratory infections which can be caused by one or more pathogens (bacteria, viruses, and fungi) including, but not limited to, those causing the various forms of upper respiratory tract infection (common cold), influenza, bronchitis, laryngitis, etc. in human being, by using a non-toxic, easily accessible to public “effective formula” to attack the newly activated or the newly invading pathogen and rendering it ineffective. If the infection has already fully taken effect, the present method helps reduce the symptoms of the infection (illness) and its duration by preventing occurrence of secondary infections. This method may also be applied to other mammals.Type: ApplicationFiled: April 10, 2003Publication date: November 20, 2003Inventor: Saeed Rezakhany
-
Patent number: 6596776Abstract: The present invention relates to a naturally obtained mixture of higher molecular weight primary aliphatic alcohols which contain 20 to 34 carbon atoms. This invention also relates to the process for obtaining the alcohol mixture by extraction and purification with organic solvents from a natural product, such as beeswax with and without saponification of the natural product. The alcohol mixture obtained from beeswax has enhanced purity and contains a mixture of alcohols having 20, 22, 24, 26, 27, 28, 30, 32 and 34 carbon atoms. The alcohol mixture is useful in pharmaceutical compositions, foodstuffs and dietary supplements and is effective for lowering cholesterol and LDL-cholesterol and increasing HDL-cholesterol levels so that it is effective in treating hypercholesterolemia.Type: GrantFiled: April 25, 2002Date of Patent: July 22, 2003Assignee: Hauser, Inc.Inventors: William R. Gamble, Zhengjie Liu, David T. Bailey, Pedro P. Perez, Dean P. Stull, Steven L. Richheimer, Rebecca L. Nichols, Rod Lenoble
-
Publication number: 20030113358Abstract: A method has been discovered for attracting Colorado potato beetles to an area of object or area, which method involves treating the object or area with a Colorado potato beetle attracting composition (with or without an insecticide) containing a carrier material and a Colorado potato beetle attracting effective amount of (a) (Z)-3-hexenyl acetate, (±)-linalool, nonanal, and methyl salicylate, (b) (Z)-3-hexenyl acetate, (±)-linalool, and methyl salicylate, (c) (Z)-3-hexen-1-ol, (E)-2-hexen-1-ol, and (±)-linalool, (d) (Z)-3-hexenyl acetate and methyl salicylate, or (e) (Z)-3-hexenyl acetate and (±)-linalool.Type: ApplicationFiled: September 13, 2002Publication date: June 19, 2003Inventors: Joseph C. Dickens, A. Randall Alford
-
Publication number: 20030069191Abstract: Pantethinesulphonic acid and/or a salt thereof as a free-radical scavenger. Prevent or combat the harmful effects of UV and/or pollution on the skin, loss of firmness and/or elasticity of the skin, etc.Type: ApplicationFiled: September 17, 2002Publication date: April 10, 2003Applicant: L'OREALInventors: Anthony Potin, Philippe Touzan, Pascale Pelletier
-
Patent number: 6511968Abstract: The invention provides a method for treating, preventing, or reducing the risk of developing a condition selected from the group consisting of acute coronary ischemic syndrome, thrombosis, thromboembolism, thrombotic occlusion and reocclusion, restenosis, transient ischemic attack, and first or subsequent thrombotic stroke, in a patient, comprising administering to the patient a therapeutically effective amount of an antiplatelet agent in combination with a therapeutically effective amount of a COX-2 inhibitor. The invention also provides a pharmaceutical composition comprising a therapeutically effective amount of a COX-2 inhibitor, or a pharmaceutically acceptable salt thereof, and an antiplatelet agent, or a pharmaceutically acceptable salt thereof.Type: GrantFiled: October 23, 2000Date of Patent: January 28, 2003Assignee: Merck & Co., Inc.Inventor: Steven A. Nichtberger
-
Publication number: 20030012830Abstract: Disclosed herein are topical compositions and methods for using the same to relieve pain in humans, such as pain associated with cancer, bone injuries, old age, and many other forms of pain. Specifically, the present compositions comprise an effective amount of acetone, a salicylate-based compound and an emollient. In addition, the present compositions further comprise one or more compounds including, but not limited to, terpenes and essential oils. The present compositions may be in the form of a liquid (preferably a slightly viscous liquid) or other forms including, but not limited to, salves, creams, gels, ointments or sprays.Type: ApplicationFiled: July 31, 2001Publication date: January 16, 2003Inventor: Robert Small
-
Publication number: 20030008008Abstract: Physiologically acceptable films, including edible films, are disclosed. The films include a water soluble film-forming polymer such as pullulan. Edible films are disclosed that include pullulan and antimicrobially effective amounts of the essential oils thymol, methyl salicylate, eucalyptol and menthol. The edible films are effective at killing the plaque-producing germs that cause dental plaque, gingivitis and bad breath. The film can also contain pharmaceutically active agents. Methods for producing the films are also disclosed.Type: ApplicationFiled: February 21, 2002Publication date: January 9, 2003Inventors: Sau-Hung Spence Leung, Robert S. Leone, Lori D. Kumar, Neema Kulkarni, Albert F. Sorg
-
Patent number: 6475526Abstract: One aspect of the invention relates to anti-viral composition containing at least one zinc compound and at least one phenolic antioxidant (and optionally other ingredients such as at least one analgesic) at least one hydrocarbyl containing compound, and water. Another aspect of the invention relates to a method of treating lesionous symptoms of a viral infection involving applying an effective amount of the zinc containing anti-viral composition to the lesions.Type: GrantFiled: June 5, 2001Date of Patent: November 5, 2002Inventor: Jeffrey B. Smith
-
Patent number: 6472381Abstract: The invention comprises the administration of an effective amount of a tellurium compound to a patients who is afflicted with psoriasis. The tellurium compound is administered either systemically or topically to one who is afflicted with psoriasis in an amount which is effective to alleviate the symptoms of psoriasis.Type: GrantFiled: October 12, 2001Date of Patent: October 29, 2002Assignee: Biomas Inc.Inventors: Michael Albeck, Benjamin Sredni
-
Patent number: 6440406Abstract: The present invention provides a composition for attracting scarabs. Liquid and solid formulations are provided, along with methods for their use, for controlling or eliminating scarabs, and/or protecting plants susceptible to scarab damage.Type: GrantFiled: June 12, 2000Date of Patent: August 27, 2002Assignees: The United States of America as represented by the Secretary of Agriculture, The Texas A&M University SystemInventors: Juan D. Lopez, Jr., Robert L. Crocker, Ted N. Shaver
-
Patent number: 6436916Abstract: Ibuprofen-aspirin compounds useful in treating aspirin or ibuprofen-treatable conditions and hydroxymethylacylfulvene analogs useful as antitumor drugs.Type: GrantFiled: September 18, 2001Date of Patent: August 20, 2002Inventor: Alvin Guttag
-
Patent number: 6423697Abstract: An anti-inflammatory, either a NSAID or glucocorticoid steroid in the form of an ointment, cream, lotion, gel, powder, tablet, paste, film, tape or adhesive bandage, provided with appropriate vehicle to allow specific adherence to specific gingival areas, for topical treatment of inflammation. This composition and the method of using same is used to prevent or relieve migraine, tension-type headache, post-traumatic headache, facial pain and cervical muscle spasm.Type: GrantFiled: July 26, 2000Date of Patent: July 23, 2002Inventor: Mark Friedman
-
Publication number: 20020065254Abstract: Ibuprofen-aspirin compounds useful in treating aspirin or ibuprofen-treatable conditions and hydroxymethylacylfulvene analogs useful as antitumor drugs.Type: ApplicationFiled: September 18, 2001Publication date: May 30, 2002Inventor: Alvin Guttag
-
Publication number: 20010049364Abstract: The present invention relates to a method for the prevention of cancer or the initiation and/or progression of cancer in a human comprising administration to the human a combination dosage of a cyclooxygenase (COX) inhibitor, a vitamin D3 including analogues and metabolites thereof and calcium. In a further embodiment the invention relates to the use of the combination dosage for the preparation of a medicament and to such pharmaceutical preparations. In a further aspect the invention relates to a method for reducing the effective dosage of ASA in a chemoprofylactive treatment of colorectal cancer in a human by co-administration with a non toxic dosage of a vitamin D3 including analogues and metabolites thereof and Ca in the form of a combination dosage.Type: ApplicationFiled: April 5, 2001Publication date: December 6, 2001Inventor: Raskov Hans Henrik
-
Publication number: 20010049363Abstract: Oral compositions for treating and/or preventing gingivitis are provided. The compositions include at least one NSAID, thymol, methyl salicylate, menthol and eucalyptol. The NSAID, thymol, methyl salicylate, menthol and eucalyptol are present in the composition in synergistically effective amounts. The compositions can be provided in the form of, e.g., mouthwashes or toothpastes, and are not only effective against gingivitis, but can also prevent or treat halitosis and other detrimental conditions of the oral cavity.Type: ApplicationFiled: January 16, 2001Publication date: December 6, 2001Applicant: Warner-Lambert CompanyInventors: Michael Rubin, Pauline Pan, Frank Volpe
-
Publication number: 20010012840Abstract: Jojoba alcohol, a mixture of long chain monounsaturated alcohols, is an oily liquid at moderate ambient temperatures. It is readily absorbed by human skin where it relieves irritation and inhibits the formation of lesions caused by viruses. The inhibitory action is applicable to enveloped viruses which express as sores at dermal surfaces in humans. When applied topically to an incipent herpes episode, it will quickly penetrate the epidermis to the subdermal vascular cells and suppress viral replication which leads to inflammation and the formation of blisters on the face, genital and other skin and mucosal areas. Compositions of certain low molecular weight organic acids in jojoba alcohol enhance antiviral activity. Jojoba alcohol is a carrier and transdermal delivery system for these and other pharmacologically active agents for the relief of pain and treatment of other conditions which occur at or under the surface of the skin. Topically applied jojoba alcohol is non-toxic and safe for animals and humans.Type: ApplicationFiled: February 28, 2001Publication date: August 9, 2001Inventor: Anthony J. Verbiscar
-
Publication number: 20010011097Abstract: A method of reducing or inhibiting mucositis in a patient, which includes administering an inflammatory cytokine inhibitor or a mast cell inhibitor, or a combination thereof, is disclosedType: ApplicationFiled: March 7, 2001Publication date: August 2, 2001Inventors: Stephen T. Sonis, Edward G. Fey
-
Publication number: 20010005721Abstract: Described is a method and heel cream composition for healing epidermal cracks on the soles of feet, primarily on heels, having active ingredients consisting of a combination of a safe and effective amount of salicylic acid and hydrocortisone in some preferred embodiments, with further embodiments further consisting of salicylic acid, hydrocortisone, boric acid, and zinc oxide. The preferred embodiments also comprise a preferred carrier for transporting the active ingredients to the heel cracks. The method of preparation includes, using a specified heat, separately mixing an oil phase, a water phase, and a medicate phase (preferably including the salicylic acid and the hydrocortisone) and then combining them. As a method of treatment, the heel cream composition should be topically applied to the skin areas having epidermal cracks about twice a day.Type: ApplicationFiled: January 29, 2001Publication date: June 28, 2001Inventor: Fereidoon Pourbastani
-
Patent number: 6225354Abstract: The present invention relates to a naturally obtained mixture of higher molecular weight primary aliphatic alcohols which contain 24 to 34 carbon atoms. This invention also relates to the process for obtaining the alcohol mixture by extraction and purification with organic solvents from beeswax without saponification ofthe beeswax. The alcohol mixture obtained from beeswax has enhanced purity and contains a mixture of alcohols having 24, 26, 27, 28, 29, 30, 32 and 34 carbon atoms. The alcohol mixture is useful in pharmaceutical compositions, foodstuffs and dietary supplements and is effective for lowering cholesterol in LDL-C levels so that it is effective in treating hypercholesterolemia. Consequently the composition may be used to reduce the risk of coronary heart disease, the atherosclerotic process (platelet hyperaggregability, ischemia and thrombosis) and also acts as an anti-inflammatory and anti-thrombotic agent.Type: GrantFiled: June 21, 1999Date of Patent: May 1, 2001Assignee: Cholesterol Control Laboratories, Inc.Inventor: Pedro P. Perez
-
Patent number: 6074634Abstract: The present invention provides an composition for attracting noctuid and/or other lepidopteran species. Liquid and solid formulations are provided, along with methods for their use, for controlling or eliminating noctuid and/or other lepidopteran species, and/or protecting plants susceptible to noctuid and/or other lepidopteran species damage.Type: GrantFiled: October 5, 1998Date of Patent: June 13, 2000Assignee: The United States of America as represented by the Secretary of AgricultureInventors: Juan D. Lopez, Jr., Ted N. Shaver, Kenneth R. Beerwinkle, Peter D. Lingren