The Additional Chalcogen Containing Hetero Ring Is Part Of A Polycyclo Ring System Patents (Class 514/263.24)
  • Inosine compounds and their use for treating or preventing an inflamation or a reperfusion disease
    Publication number: 20030040502
    Abstract: Inosine compounds, compositions comprising an inosine compound and methods for treating or preventing an inflammation disease or a reperfusion disease comprising administering an effective amount of an inosine compound to a patient in need thereof are disclosed.
    Type: Application
    Filed: March 26, 2002
    Publication date: February 27, 2003
    Applicant: Inotek Pharmaceuticals Corporation
    Inventors: Andrew L. Salzman, Csaba Szabo
  • Novel nucleosides having bicyclic sugar moiety
    Publication number: 20030028013
    Abstract: Conformationally restricted 2′, 4′-bridged nucleoside analogues are described herein. The compounds can be prepared by cyclization at C2′ and C4′ of nucleosides through a linker or linking molecule. These novel nucleosides have a desired, locked sugar pucker and are potentially useful as pharmaceutical ingredients, and especially for use in treatment of HCV.
    Type: Application
    Filed: April 30, 2002
    Publication date: February 6, 2003
    Inventors: Guangyi Wang, Zhi Hong, Haoyun An
  • Adenosine cyclic ketals: novel adenosine analogues for pharmacotherapy
    Publication number: 20020147174
    Abstract: The present invention includes a novel class of synthetic adenosine derivatives having clinically relevant and useful properties. These adenosine cyclic ketal compounds will be useful for treatment of a variety of conditions including, but not limited to, hypertension, vasodilation and ischemia.
    Type: Application
    Filed: April 5, 2001
    Publication date: October 10, 2002
    Applicant: University of Pittsburgh
    Inventors: Garth S. Jones, Edwin K. Jackson