Nutrition Enhancement Or Support Patents (Class 514/5.5)
  • Patent number: 10172375
    Abstract: An edible composition comprising peptides rich in tryptophan, which edible composition further comprises a rapidly available glucose composition and a slowly available glucose composition.
    Type: Grant
    Filed: April 9, 2009
    Date of Patent: January 8, 2019
    Assignee: DSM IP ASSETS B.V.
    Inventors: Rudolf Van Beck-hoven, Alexander Duchateau, Luppo Edens, Franciscus Kleinherenbrink, Joris Kloek, Andre L. Ross De
  • Patent number: 10117902
    Abstract: The present invention provides nutritional compositions that are employed as oral supplementation to the human diet. The compositions of the present invention provide for supplementation to the diet of the cancer patient, as well as preventative dietary supplementation aimed at supporting the human immune system for those not currently suffering from cancer. The present invention is comprised of specific combinations of selected forms of unique sets of certain vitamins, minerals, protein, carbohydrates and phytochemicals.
    Type: Grant
    Filed: July 8, 2016
    Date of Patent: November 6, 2018
    Inventor: Houn Simon Hsia
  • Patent number: 9931369
    Abstract: The present invention relates to a carbohydrate-based peritoneal dialysis fluid, containing a compound selected from the group consisting of glutamine, preferably L-glutamine; a dipeptide capable of releasing glutamine, L-glutamine in free form, preferably selected from the group consisting of glutaminyl-glycine, glycinyl-glutamine, glutaminyl-alanine, alanyl-glutamine; an oligopeptide consisting of two to seven glutamine, preferably L-glutamine residues; and mixtures thereof. The peritoneal dialysis fluids of the present invention are useful for inhibition of technical failure in a person undergoing peritoneal dialysis treatment.
    Type: Grant
    Filed: November 15, 2013
    Date of Patent: April 3, 2018
    Assignee: ZYTOPROTEC GMBH
    Inventor: Christoph Aufricht
  • Patent number: 9872515
    Abstract: The present invention provides an enteral nutritional composition with which the labor of administering water between meals can be saved. The enteral nutritional composition comprises proteins, carbohydrates and lipids, with the calories per ml of the composition being less than 1 kcal and the moisture content being 30 percent by mass or more.
    Type: Grant
    Filed: June 24, 2014
    Date of Patent: January 23, 2018
    Assignee: Nutri Co., Ltd.
    Inventors: Susumu Kawaguchi, Yoshifumi Inoue
  • Patent number: 9833013
    Abstract: The present invention provides an enteral nutritional composition with which the labor of administering water between meals can be saved. The enteral nutritional composition comprises proteins, carbohydrates and lipids, with the calories per ml of the composition being less than 1 kcal and the moisture content being 30 percent by mass or more.
    Type: Grant
    Filed: June 24, 2014
    Date of Patent: December 5, 2017
    Assignee: Nutri Co., Ltd.
    Inventors: Susumu Kawaguchi, Yoshifumi Inoue
  • Patent number: 9827216
    Abstract: The present invention relates to methods and immunonutritional compositions for preventing or mitigating paralysis of the bone marrow, caused by a tumor or neoplasm, between cycles of and after anti-cancer therapy, thereby attaining a better efficacy of the treatment. More particularly, the present invention relates to methods and immunonutritional compositions that can transiently preventing or moderating, bone marrow paralysis or neutropenia of a subject tumor-induced apoptosis or necrosis or other cell damage such that the innate and adaptive immune functions and normal physiology of the bone marrow are preserved, at least in part, which, in turn, lead to (i) a better tolerance and increased efficacy to treatment; (ii) transient augmentation or enhancement of immunocompetence of the immune cell; and (iii) optimization of the effects of and increase of immunocompetence of the immune cell weakened due to paralysis of the bone marrow, caused by a tumor or neoplasm.
    Type: Grant
    Filed: September 11, 2009
    Date of Patent: November 28, 2017
    Assignees: Nestec S.A., Institut Curie
    Inventors: Eduardo Schiffrin, Kevin Burke Miller, Dominique Brassart, Olivier Jacques Lantz, Sebastian Diego Amigorena
  • Patent number: 9486003
    Abstract: Nutritional compositions having reduced amounts of calories and high amounts of protein and methods of making and using the nutritional compositions are provided. The nutritional compositions may include a processed whole food component, a high amount of protein, and a reduced amount of calories in order to provide a patient with a pH-balanced formulation that includes the benefits of food bioactives beyond essential macro- and micronutrients without providing excessive energy. Methods of administering such nutritional compositions to patients in need of improved bone, muscle, neurological, immune, and/or overall health are also provided.
    Type: Grant
    Filed: June 28, 2011
    Date of Patent: November 8, 2016
    Assignee: Nestec S.A.
    Inventors: Doug Bolster, Zamzam Fariba Roughead, Norman Alan Greenberg, Jennifer Mager
  • Patent number: 9439448
    Abstract: A nutritional composition for improving the immunological function of a subject, including a lipid or fat; a protein source; about 5 to about 100 mg/100 kcal of a source of long chain polyunsaturated fatty acids which comprises docosahexanoic acid; and about 0.1 to about 1 mg/100 kcal of a prebiotic composition, wherein the prebiotic composition comprises at least 20% of an oligosaccharide which has a fermentation rate which is demonstrably slower than that of galacto-oligosaccharide.
    Type: Grant
    Filed: September 14, 2012
    Date of Patent: September 13, 2016
    Assignee: Mead Johnson Nutrition Company
    Inventors: Francisco J. Rosales, Eric van Tol, Gyan P. Rai, Kristin Morris, Dattatreya Banavera, Dirk Hondmann, Zeina E. Jouni, Robert J. McMahon, Deborah A. Schade, Donald Carey Walker
  • Patent number: 9421190
    Abstract: Composition comprising leucine, isoleucine, valine, threonine and lysine for use in prophylactic and/or therapeutic treatment of renal disorders in a subject, preferably an elderly subject.
    Type: Grant
    Filed: March 26, 2014
    Date of Patent: August 23, 2016
    Assignee: DETERMINANTS OF METABOLISM RESEARCH LABORATORY S.R.L.
    Inventors: Franco Conti, Francesco Saverio Dioguardi
  • Patent number: 9326963
    Abstract: The invention provides intradialytic parenteral nutrition (IDPN) solutions with low carbohydrate for the treatment of malnutrition in dialysis patients. The IDPN solutions of the invention are particularly advantageous for the treatment of malnutrition in patients who are diabetic or suffer from other glucose management related pathologies or patients who require strict fluid management.
    Type: Grant
    Filed: July 7, 2009
    Date of Patent: May 3, 2016
    Assignee: Pentec Health, Inc.
    Inventor: Eileen Moore
  • Patent number: 9308261
    Abstract: The present invention provides compositions and methods for preventing or treating diseases and disorders, the composition comprising vitamin C, vitamin E, and at least one of an omega-3 fatty acid and an omega-6 fatty acid.
    Type: Grant
    Filed: October 12, 2009
    Date of Patent: April 12, 2016
    Assignee: PREGNANT PRINCESS & CO. LTD.
    Inventor: Sarah Steinberg Greenwald
  • Patent number: 9220750
    Abstract: The present invention relates to the use of an antisecretory factor (AF) protein, peptide, derivative, homologue, and/or fragment thereof, having equivalent functional activity, and/or a pharmaceutically active salt thereof, for optimizing delivery and cellular uptake of a pharmaceutical substance and/or formulation, or a gene delivery. Typically, said pharmaceutical substance and/or formulation comprises an anticancer drug, radiation therapy, an antibiotic substance, an antiviral substance or a drug targeting posttraumatic injury, neurodegeneration, a parasite, or an inflammatory condition.
    Type: Grant
    Filed: February 11, 2010
    Date of Patent: December 29, 2015
    Assignee: LANTMANNEN AS-FAKTOR AB
    Inventors: Eva Jennische, Stefan Lange, Hans-Arne Hansson
  • Patent number: 9040075
    Abstract: Disclosed is a method of increasing lean body mass and reducing fat body mass in infants, said method comprising administration to an infant, term or preterm, a nutritional formula comprising a source of DHA and ARA. It has been found that the administration of DHA and ARA, or a source thereof, in infants can increase lean body mass and reduce fat body mass, when compared to an unsupplemented control formula, without impacting the total overall growth of the infant. This method is especially useful in preterm infants.
    Type: Grant
    Filed: December 17, 2004
    Date of Patent: May 26, 2015
    Assignee: ABBOTT LABORATORIES
    Inventors: Nancy Auestad, Joan R. Jacobs
  • Publication number: 20150133370
    Abstract: The present invention relates to dietary compositions comprising reduced level of methionine, tryptophan, all amino acids, or protein, dietary compositions comprising glycerol as a substitute for monosaccharides, disaccharides, and polysaccharides, and hypocaloric or calorie free diets with reduced level of energy, carbohydrates, or protein. Also disclosed are methods of using these compositions and diets, as well as fasting, to protect subjects against chemotherapy, radiotherapy, oxidative stress, or aging.
    Type: Application
    Filed: September 26, 2014
    Publication date: May 14, 2015
    Inventor: Valter Longo
  • Publication number: 20150126441
    Abstract: Nutritive proteins comprising no phenylalanine (Phe) are provided. In some embodiments the nutritive proteins comprise at least one of a level of a) a ratio of branch chain amino acid residues to total amino acid residues present in the nutritive protein equal to or greater than the ratio of branch chain amino acid residues to total amino acid residues present in a benchmark protein; b) a ratio of leucine residues to total amino acid residues present in the nutritive protein equal to or greater than the ratio of leucine residues to total amino acid residues present in a benchmark protein; and c) a ratio of essential amino acid residues to total amino acid residues present in the nutritive protein equal to or greater than the ratio of essential amino acid residues to total amino acid residues present a benchmark protein.
    Type: Application
    Filed: March 15, 2013
    Publication date: May 7, 2015
    Inventors: David Arthur Berry, Brett Adam Bohigian, Nathaniel W. Silver, Michael J. Hamill, Geoffrey von Maltzahn, John F. Kramarczyk, Rajeev Chillakuru
  • Publication number: 20150119322
    Abstract: Provided is a composition and method for modulating serotonergic receptor expression, reducing anxiety-like behavior and stress-induced inflammatory response in a pediatric subject, the method including administering to the pediatric subject a nutritional composition including lactoferrin from a non-human source and a prebiotic composition including polydextrose and/or galactooligosaccharides. Further provided is a method for reducing constipation in a pediatric subject by providing a nutritional composition including lactoferrin from a non-human source and a prebiotic composition including polydextrose and/or galactooligosaccharides.
    Type: Application
    Filed: November 7, 2014
    Publication date: April 30, 2015
    Inventors: Maciej Chichlowski, Brian Berg, Zeina Jouni, Anja Wittke, Rosaline Waworuntu
  • Publication number: 20150099002
    Abstract: The present invention relates to means and methods for enhancing intestinal function in poultry, leading to an increase in food conversion ratio and in total weight gain. Particularly, the present invention relates to insulin-containing feed formulations enhancing intestinal function and weight gain in poultry.
    Type: Application
    Filed: December 15, 2014
    Publication date: April 9, 2015
    Inventors: Naim Shehadeh, Lora Eshkar-Sebban, Aviv Hanien, Sharon Devir
  • Patent number: 8999926
    Abstract: A nutritional composition for infants comprises a protein source, a lipid source and a carbohydrate source wherein the lipid source includes at least 16 wt % linoleic acid and at least 2 wt % ?-linolenic acid expressed as a percentage of total fatty acid content in each case and in amounts such that the ratio of linoleic acid:?-linolenic acid is in the range from 1 to 10.
    Type: Grant
    Filed: March 6, 2013
    Date of Patent: April 7, 2015
    Assignee: Nestec S.A.
    Inventors: Catherine Mace, Olivier Kevork Aprikian, Etienne Pouteau
  • Patent number: 8987196
    Abstract: The present invention concerns an improved balance of the essential branched chain amino acids leucine, isoleucine and valine in infant formula.
    Type: Grant
    Filed: March 25, 2011
    Date of Patent: March 24, 2015
    Assignee: N.V. Nutricia
    Inventors: Johannes Bernard Van Goudoever, Eline Marleen Van Der Beek, Marieke Abrahamse-Berkeveld, Günther Boehm
  • Publication number: 20150080296
    Abstract: Nutritive proteins are provided. In some embodiments the nutritive proteins comprise a protein digestibility corrected amino acid score (PDCAAS) that exceeds a benchmark protein. Also provided are nucleic acids encoding the proteins, recombinant microorganisms that make the proteins, methods of making the proteins using recombinant microorganisms, compositions that comprise the proteins, and methods of using the proteins, among other things.
    Type: Application
    Filed: March 15, 2013
    Publication date: March 19, 2015
    Inventors: Nathaniel W. Silver, Geoffrey von Maltzahn, Michael J. Hamill, David Arthur Berry
  • Patent number: 8975222
    Abstract: The present invention provides a ketogenic diet in the form of a sterile shelf stable ready to use formula, in particular a tube feed, comprising casein and dietary fiber.
    Type: Grant
    Filed: June 6, 2011
    Date of Patent: March 10, 2015
    Assignee: N.V. Nutricia
    Inventors: Andrew Sean Lynch, Simon Anders, Paul Ronald
  • Publication number: 20150017097
    Abstract: The invention features sincalide formulations that include an effective amount of sincalide, a bulking agent/tonicity adjuster, a stabilizer, a surfactant, a chelator, and a buffer. The invention also features kits and methods for preparing improved sincalide formulations as well as methods for treating, preventing, and diagnosing gall bladder-related disorders using sincalide formulations.
    Type: Application
    Filed: October 2, 2014
    Publication date: January 15, 2015
    Applicant: BRACCO DIAGNOSTICS INC.
    Inventors: Edmund C. METCALFE, Jo Anna MONTEFERRANTE, Margaret NEWBORN, Irene KUCHAREWICZ ROPIAK, Ernst SCHRAMM, Gregory W. WHITE, Julius P. ZODDA
  • Publication number: 20140364361
    Abstract: The present invention relates in general to a shelf-stable liquid enteral composition for providing nutrition, either as a supplement, or as a complete nutrition, with a high protein content of a non-hydrolysed globular protein, in particular a whey protein.
    Type: Application
    Filed: July 21, 2014
    Publication date: December 11, 2014
    Applicant: N.V. Nutricia
    Inventors: Marcel MINOR, Koenraad Gerard Christoffel Weel, Natalie Elizabeth Hotrum
  • Patent number: 8889617
    Abstract: Provided is a liquid food composition capable of semi-solidifying in the stomach, which is a one-pack type product containing a water-soluble dietary fiber preliminarily added thereto and in the form of a liquid that can be easily taken, and stably sustains the liquid nature thereof during distribution and storage. The liquid food composition, which is capable of semi-solidifying in an acidic region, comprises a water-soluble dietary fiber (a), a specific metal compound (b), a protein (c) and an emulsifier (d), and the particle size distribution of particles contained in said liquid food composition shows two or more peaks in a neutral region.
    Type: Grant
    Filed: December 17, 2010
    Date of Patent: November 18, 2014
    Assignee: Kaneka Corporation
    Inventors: Hiroaki Inoue, Yui Kawashima, Kazuya Hamada, Shinichi Yokota, Hiromi Maeda, Tatsumasa Mae, Jun Tomono
  • Patent number: 8865646
    Abstract: The present invention relates to dietary compositions comprising reduced level of methionine, tryptophan, all amino acids, or protein, dietary compositions comprising glycerol as a substitute for monosaccharides, disaccharides, and polysaccharides, and hypocaloric or calorie free diets with reduced level of energy, carbohydrates, or protein. Also disclosed are methods of using these compositions and diets, as well as fasting, to protect subjects against chemotherapy, radiotherapy, oxidative stress, or aging.
    Type: Grant
    Filed: April 24, 2009
    Date of Patent: October 21, 2014
    Assignee: University of South California
    Inventor: Valter Longo
  • Publication number: 20140294877
    Abstract: The present invention is directed to an inventive polymeric carrier molecule according to generic formula (I) and variations thereof, which allows for efficient transfection of nucleic acids into cells in vivo and in vitro, a polymeric carrier cargo complex formed by a nucleic acid and the inventive polymeric carrier molecule, but also to methods of preparation of this inventive polymeric carrier molecule and of the inventive polymeric carrier cargo complex. The present invention also provides methods of application and use of this inventive polymeric carrier molecule and the inventive polymeric carrier cargo complex as a medicament, for the treatment of various diseases, and in the preparation of a pharmaceutical composition for the treatment of such diseases.
    Type: Application
    Filed: March 4, 2014
    Publication date: October 2, 2014
    Applicant: CUREVAC GMBH
    Inventors: Patrick BAUMHOF, Thomas SCHLAKE
  • Publication number: 20140271552
    Abstract: The present disclosure relates to nutritional compositions including a protein equivalent source including a peptide component comprising selected peptides from Tables 1 and 2 disclosed herein. The protein equivalent source may further include intact protein, hydrolyzed protein, including partially hydrolyzed protein, or combinations thereof. The disclosure further relates to methods of reducing the incidence of autoimmune disease and/or diabetes mellitus by providing said nutritional compositions to a target subject, which includes a pediatric subject.
    Type: Application
    Filed: March 15, 2013
    Publication date: September 18, 2014
    Inventors: Dirk Hondmann, Eric A.F. van Tol, Gabriele Gross, Marieke H. Schoemaker, Teartse Tim Lambers
  • Patent number: 8835716
    Abstract: The present invention relates to processes for modifying the thermal and/or digestion properties of corn starches and corn flours.
    Type: Grant
    Filed: December 28, 2007
    Date of Patent: September 16, 2014
    Assignee: Bayer Cropscience AG
    Inventor: Claus Frohberg
  • Patent number: 8815233
    Abstract: A method of utilizing the chymotrypsin level of an individual as a measure of the success of secretin, other neuropeptides, and peptides or digestive enzyme administration to such individuals, and in particular, as a prognosticative of potential secretin, other neuropeptides, peptides, and digestive enzyme administration for persons having ADD, ADHD, Autism and other PDD related disorders.
    Type: Grant
    Filed: April 16, 2012
    Date of Patent: August 26, 2014
    Assignee: Curemark LLC
    Inventor: Joan M. Fallon
  • Patent number: 8785380
    Abstract: The present invention relates to a formulation containing curcuminoids exhibiting enhanced in vivo bioavailability and resultant improved efficacy, said formulation comprising curcuminoids and a gel forming, non digestive and soluble dietary polysaccharide fiber galactomannan matrix and proteins derived from fenugreek [Trigonella Foenum graecum]. The invention also relates to a process for producing the formulation and extracting non-digestible soluble dietary polysaccharide fiber galactomannans containing proteins from fenugreek seeds.
    Type: Grant
    Filed: January 27, 2012
    Date of Patent: July 22, 2014
    Assignee: M/S Akay Flavours & Aromatics Pvt Ltd.
    Inventors: Krishnakumar Illathu Madhavamenon, Abhilas Ravi, Dinesh Kumar, Balu Paulose Maliakel
  • Publication number: 20140200176
    Abstract: The present disclosure relates to nutritional composition(s) comprising a carbohydrate source, a protein source, a fat source and magnesium threonate. Magnesium threonate may provide neurological health benefits when consumed. The disclosure further relates to methods of promoting neurological health by providing a nutritional composition comprising magnesium threonate. Additionally, the disclosure relates to methods of promoting GI tolerance in a pediatric subject by providing a nutritional composition comprising magnesium threonate.
    Type: Application
    Filed: January 11, 2013
    Publication date: July 17, 2014
    Applicant: Mead Johnson Nutrition Company
    Inventor: BRIAN BERG
  • Patent number: 8778404
    Abstract: The present inventors discovered that the onset of galactosamine hepatopathy is suppressed by nutritional compositions comprising as essential ingredients: whey protein hydrolysates; lecithin and oils and fats high in oleic acid, which are able to improve the lipid metabolism; and palatinose having an insulin-sparing effect. Furthermore, the whey protein hydrolysate included in the nutritional compositions was found to suppress endotoxin-induced TNF-a and interleukin 6 (IL-6) production in macrophages.
    Type: Grant
    Filed: May 30, 2009
    Date of Patent: July 15, 2014
    Assignee: Meiji Co., Ltd.
    Inventors: Hisae Kume, Makoto Yamaguchi, Kenji Mizumoto, Hajime Sasaki
  • Patent number: 8772230
    Abstract: This invention relates to the use of niacin and/or trigonelline compounds to increase muscle weight during periods of activity or to inhibit muscle loss during periods of inactivity.
    Type: Grant
    Filed: June 10, 2010
    Date of Patent: July 8, 2014
    Assignee: DSM IP Assets B.V.
    Inventors: Angelika Friedel, Karin Kuratli, Christof Wehrli, Karin Wertz, Swen Wolfram, Ying Wang-Schmidt
  • Patent number: 8759283
    Abstract: A method to measure enhancement in the quality of life of an animal fed a super senior pet food composition comprising quantitating the gene expression levels of one or more genes in said animal and comparing said levels in the animal to levels in the animal prior to administration of said super senior pet food composition. A method to enhance the quality of life of an animal by modulating the expression level of one or more genes in said animal in order to mimic the pattern of expression seen in vivo after administration of a super senior pet food composition.
    Type: Grant
    Filed: September 24, 2013
    Date of Patent: June 24, 2014
    Assignee: Hill's Pet Nutrition, Inc.
    Inventors: Ryan Michael Yamka, Kim Gene Friesen
  • Publication number: 20140171360
    Abstract: A nutritional supplement, a method for increasing the bacterial mass in the rumen of a ruminant and a nutritional preparation and corresponding uses. A nutritional supplement including proteins with a degree of hydrolysis above 28% and/or which have more than 23 mg ?-amino nitrogen per gram of protein and/or have more than 10% of free amino acids. The hydrolyzed proteins are animal proteins, preferably hemoglobin. The supplement is supplied orally, included in a nutritional preparation, in liquid, concentrated or dehydrated form.
    Type: Application
    Filed: July 6, 2012
    Publication date: June 19, 2014
    Applicant: APC EUROPE S.A.
    Inventors: Francisco Javier Polo Pozo, Carmen Rodriguez Canel, Alejandro Bach Ariza, Anna Aris Giralt
  • Publication number: 20140135262
    Abstract: The present invention relates generally to the field of neuronal health and neuronal protection. One embodiment of the present invention relates to a composition that can be used for the protection of the enteric nervous system from neurodegeneration. Disorders linked to an impaired enteric nervous system can be treated or prevented by the administration of lactoferrin containing compositions according to the present invention.
    Type: Application
    Filed: November 6, 2013
    Publication date: May 15, 2014
    Applicant: NESTEC S.A.
    Inventors: Magali Faure, Bing Wang, Jeroen Schmitt
  • Patent number: 8685914
    Abstract: The present invention provides: (1) crystals of a dipeptide which do not substantially comprise a dipeptide comprising D-amino acid as a constituent or a polypeptide consisting of three or more amino acids; and (2) crystals of a dipeptide which do not substantially comprise a dipeptide comprising D-amino acid as a constituent, a polypeptide consisting of three or more amino acids, or an amino acid amide; and a process for producing the dipeptide crystals.
    Type: Grant
    Filed: March 29, 2006
    Date of Patent: April 1, 2014
    Assignee: Kyowa Hakko Bio Co., Ltd.
    Inventors: Shin-ichi Hashimoto, Kazuhiko Tabata, Shizuo Tsuchiya, Tetsuo Nishimura
  • Publication number: 20140065071
    Abstract: The invention features sincalide formulations that include an effective amount of sincalide, a bulking agent/tonicity adjuster, a stabilizer, a surfactant, a chelator, and a buffer. The invention also features kits and methods for preparing improved sincalide formulations as well as methods for treating, preventing, and diagnosing gall bladder-related disorders using sincalide formulations.
    Type: Application
    Filed: October 28, 2013
    Publication date: March 6, 2014
    Inventors: Edmund C. METCALFE, Jo Anna MONTEFERRANTE, Margaret NEWBORN, Irene KUCHAREWICZ ROPIAK, Ernst SCHRAMM, Gregory W. WHITE, Julius P. ZODDA
  • Publication number: 20140056983
    Abstract: The invention concerns a composition based on a mixture of eugenol and cinnamaldehyde, as food additive for feeding ruminants. The composition may be incorporated in a food additive or a salt block. The eugenol and the cinnamaldehyde may be natural or identical natural constituents. Administering the composition of the food additive increases meat production and milk production.
    Type: Application
    Filed: October 7, 2013
    Publication date: February 27, 2014
    Applicants: ADM Alliance Nutrition, Inc., AXIS FRANCE S.A.S.
    Inventors: Francois Gautier, Christopher Kamel, Sergio Calsamiglia, Perry Doane
  • Publication number: 20140051627
    Abstract: The invention provides a composition and method for providing nutritional support to obese patients. The composition has an energy density between 0.4 and 0.9 kcal/ml and comprises a protein source which comprises at least 30% by weight whey protein and provides at least 30% of the total calories of the composition. The composition may include a carbohydrate source and a lipid source. Preferably at least 50% by weight of the protein source is whey protein. The invention further extends to use of the composition in the preventin of treatment of malnutrition in obese patients.
    Type: Application
    Filed: October 14, 2013
    Publication date: February 20, 2014
    Applicant: NESTEC S.A.
    Inventor: Claudia Roessle
  • Publication number: 20140044685
    Abstract: Nutritional compositions for maximizing muscle protein synthesis while minimizing the catabolism of muscle proteins and methods of using same are provided. In this manner, the nutritional compositions may provide for retention of lean body mass, which helps to avoid loss of independence and functionality, as well as to improve quality of life especially in the elderly at risk of sarcopenia and frailty. The nutritional compositions include ?-hydroxyisocaproic acid and citrulline. The composition may include other functional ingredients such as, but not limited to whey protein including whey protein micelles, prebiotic fibers, ?-keto-glutarate, eicosapentaenoic acid, L-carnitine, nucleotides, and amino acids. Methods of administering such nutritional products to individuals in need of same are also provided.
    Type: Application
    Filed: April 18, 2012
    Publication date: February 13, 2014
    Applicant: NESTEC S.A.
    Inventors: Norman Alan Greenberg, Denis Breuille, Zamzam Kabiry (Fariba) Roughead, Doug Bolster, Jennifer Mager
  • Publication number: 20140037602
    Abstract: Nutritional compositions for improving, treating and/or preventing various medical conditions and methods of using same are provided. The medical conditions may include allergies, autoimmune diseases, among others. The nutritional compositions include branched chain fatty acids and may include other functional ingredients such as, but not limited to probiotics, nucleotides and amino acids. Methods of administering such nutritional products to individuals in need of same are also provided.
    Type: Application
    Filed: April 12, 2012
    Publication date: February 6, 2014
    Applicant: NESTEC S.A.
    Inventors: Doug Bolster, Norman Alan Greenberg, Jennifer Mager, Zamzam Kabiry (Fariba) Roughead
  • Publication number: 20140030241
    Abstract: Nutritional compositions having dietary nucleotides, ?-3 fatty acids and citrulline are provided. The nutritional compositions may be formulated to improve T cell function, increase arginine availability in vivo, regulate myeloid-derived suppressor cells (“MDSC”), and decrease the risk and/or severity of infection after surgery or trauma. Methods of making, using and administering such nutritional compositions to individuals in need of same are also provided. Methods for modulating the affects of MDSC's are also provided.
    Type: Application
    Filed: March 15, 2012
    Publication date: January 30, 2014
    Applicant: NESTEC S.A.
    Inventor: Norman Alan Greenberg
  • Patent number: 8618047
    Abstract: The invention is directed to liquid enteral nutritional compositions comprising a protein fraction comprising more than 25 weight % and up to 80 weight % of a vegetable protein comprising at least a source of pea protein, and a fat fraction comprising (a) 8 to 15 weight % of linoleic acid; (b) 3.0 to 6.0 weight % of a combination of alpha-linolenic acid, docosahexaenoic acid and eicosapentaenoic acid, wherein the amount of ALA is >2.5 weight % and the combined amount of DHA and EPA is ?2.5 weight %; (c) 10 to 20 weight % of at least one medium-chain fatty acid; and (d) 35 to 79 weight % of at least one mono-unsaturated fatty acid. The compositions provide for a healthy and balanced diet, which is well-tolerated and minimises clinical complications that are frequently associated with the administration of enteral nutrition in patients using tube feeding, especially with respect to a reduced gastric emptying.
    Type: Grant
    Filed: July 27, 2012
    Date of Patent: December 31, 2013
    Assignee: N.V. Nutricia
    Inventors: Zandrie Hofman, Rogier Daniël van Anholt, Wynette Hermina Agnes Kiers, Marianne Klebach, Marloes Heleen van Beusekom
  • Patent number: 8613918
    Abstract: A method of utilizing the chymotrypsin level of an individual as a measure of the success of secretin, other neuropeptides, and peptides or digestive enzyme administration to such individuals, and in particular, as a prognosticative of potential secretin, other neuropeptides, peptides, and digestive enzyme administration for persons having ADD, ADHD, Autism and other PDD related disorders.
    Type: Grant
    Filed: May 25, 2012
    Date of Patent: December 24, 2013
    Assignee: Curemark LLC
    Inventor: Joan M. Fallon
  • Patent number: 8604168
    Abstract: Medical foods containing glycomacroprotein and additional supplemented amounts of arginine, leucine, and optionally other amino acids, such as tyrosine, are disclosed. The medical foods can be used to provide the complete protein requirements for patients having metabolic disorders such as phenylketonuria.
    Type: Grant
    Filed: June 11, 2010
    Date of Patent: December 10, 2013
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Denise M. Ney, Mark R. Etzel
  • Patent number: 8592369
    Abstract: The present invention relates generally to the field of neuronal health and neuronal protection. One embodiment of the present invention relates to a composition that can be used for the protection of the enteric nervous system from neurodegeneration. Disorders linked to an impaired enteric nervous system can be treated or prevented by the administration of lactoferrin containing compositions according to the present invention.
    Type: Grant
    Filed: May 7, 2010
    Date of Patent: November 26, 2013
    Assignee: Nestec S.A.
    Inventors: Magali Faure, Bing Wang, Jeroen Schmitt
  • Patent number: 8586077
    Abstract: A nutritional composition for infants comprises a protein source, a lipid source and a carbohydrate source wherein the lipid source includes at least 16 wt % linoleic acid and at least 2 wt % ?-linolenic acid expressed as a percentage of total fatty acid content in each case and in amounts such that the ratio of linoleic acid:?-linolenic acid is in the range from 1 to 10.
    Type: Grant
    Filed: December 16, 2009
    Date of Patent: November 19, 2013
    Assignee: Nestec S.A.
    Inventors: Catherine Mace, Olivier Kevork Aprikian, Etienne Pouteau
  • Publication number: 20130302448
    Abstract: A phytin aqueous solution including at least one alpha-hydroxylated carboxylic acid and phytin in a solubilized form, preferably in a concentration ranging from 70 g/L to 270 g/L, and in that it has a pH value ranging from 3 to 5. The phytin aqueous solution may be used in the preparation of a liquid nutritional supplement and in the preparation of a cosmetic composition.
    Type: Application
    Filed: May 10, 2012
    Publication date: November 14, 2013
    Inventor: Guy PARC
  • Publication number: 20130296233
    Abstract: The present disclosure provides a dietary supplement that includes plant ferritin; and methods of use of such a supplement.
    Type: Application
    Filed: September 7, 2011
    Publication date: November 7, 2013
    Applicant: CHILDREN'S HOSPITAL & RESEARCH CENTER AT OAKLAND
    Inventor: Elizabeth C. Theil