With An Additional Active Ingredient Patents (Class 514/500)
  • Patent number: 6387415
    Abstract: Metal-containing biocides for treating swimming pool water, spas, cooling towers, or other industrial applications without staining are disclosed. The biocidal compositions include a source of metal and a polymeric sequestering agent. The polymeric sequestering agent may be a water-soluble anionic or cationic polymer. Conventional sequestering agents may also be included in the composition.
    Type: Grant
    Filed: April 1, 1998
    Date of Patent: May 14, 2002
    Assignee: Bio-Lab, Inc.
    Inventor: John P. Garris
  • Patent number: 6387412
    Abstract: A storage stable magnesium oxychloride coated granular animal feed mineral supplement composition resistant to disintegration cause by moisture absorption and attrition, comprising granular mineral nutrients useful as animal feed supplements and magnesium oxychloride coatings amounting to between 0.5 and 10.0 percent of the weight of the granules, formed on the granules of mineral nutrients by coreaction of magnesium chloride and magnesium oxide. An additional coating of between 0.2 and 2.0 percent magnesium stearate formed on the magnesium oxychloride may be used to decrease the rate of wetting of the granular animal feed mineral supplements.
    Type: Grant
    Filed: April 14, 2000
    Date of Patent: May 14, 2002
    Assignee: Agri-Nutrients Technology Group, Inc.
    Inventor: William P. Moore
  • Patent number: 6352706
    Abstract: An ingestible mollusc poison contains a simple metal compound, an activity enhancing additive such as ethylene diamine disuccinic acid (EDDS) and derivatives thereof, and a carrier material edible to molluscs. In one embodiment the active agent of the mollusc poison may be in the form of a metal complex of EDDS. The composition may be used alone or in conjunction with molluscicidal co-active agents and/or fertilizers.
    Type: Grant
    Filed: February 1, 1999
    Date of Patent: March 5, 2002
    Assignee: W. Neudorff GmbH KG
    Inventor: George S. Puritch
  • Patent number: 6340384
    Abstract: The present invention provides a composition comprising an amine oxide and an aqueous copper amine complex. Another embodiment of the present invention is a method for preserving and/or waterproofing a wood substrate by contacting the composition with the wood substrate. Yet another embodiment is an article comprising a wood substrate and the composition of the present invention. This composition has high efficacy against fungi, including copper tolerant fungi such as brown rot and soft rot, and is phase stable at high concentrations. Additionally, the amine oxide in the composition may impart waterproofing properties. The composition of the present invention is halide free and is environmentally friendly.
    Type: Grant
    Filed: May 24, 2000
    Date of Patent: January 22, 2002
    Assignee: Lonza Inc.
    Inventor: Leigh Walker
  • Publication number: 20020004517
    Abstract: There are described the use of &agr;-(4-chlorophenyl)-&agr;-(1-cyclopropylethyl)-1H-1,2,4-triazole-1-ethanol as a microbicide for the protection of industrial materials, and compositions containing this compound.
    Type: Application
    Filed: July 10, 2001
    Publication date: January 10, 2002
    Inventors: Lutz Heuer, Peter Wachtler, Michael Schwamborn, Martin Kugler, Hans-Ulrich Buschhaus
  • Publication number: 20010048950
    Abstract: A method for stabilizing dilute solutions of 3-isothiazolone compounds against the formation of unwanted brown precipitate in the presence of low levels of copper, by the addition of 2 to 50% of selected water-soluble organic solvents, is disclosed. Preferably, the aqueous solutions are substantially free of metal nitrate, metal nitrite and magnesium salt stabilizers.
    Type: Application
    Filed: January 12, 2001
    Publication date: December 6, 2001
    Inventor: Beverly Jean El A'mma
  • Publication number: 20010006684
    Abstract: Wood preservatives contain a copper compound, an alkanolamine, a triazole, an emulsifier and/or a phosphonium compound and are used for impregnating wood.
    Type: Application
    Filed: November 3, 1998
    Publication date: July 5, 2001
    Inventors: REIMER GOETTSCHE, HANS-VOLKER BORCK
  • Patent number: 6255331
    Abstract: Disclosed are biocidal compositions comprising mixtures of formaldehyde-releasing imidazolidines, such as 1,3-dimethylol-5,3-dimethylhydantoin, and 3-isothiazolones stabilized with low levels of copper salts.
    Type: Grant
    Filed: August 16, 2000
    Date of Patent: July 3, 2001
    Assignee: Rohm and Haas Company
    Inventors: Beverly Jean El A'mma, Susan Lynn Nagahashi
  • Patent number: 6255341
    Abstract: In its broadest aspect, the present invention is directed to the discovery of immunonutritional products that are useful in reducing the immunological system suppression that results from stress. The stress may be in the form of physical exertion, mental exhaustion, disease states and the like. In one embodiment, the invention relates to a nutritional composition comprising a structured glyceride component and an antioxidant system. This nutritional composition has been shown to be highly effective in reducing immune system down regulation or dysregulation as a result of stress.
    Type: Grant
    Filed: March 12, 1999
    Date of Patent: July 3, 2001
    Assignee: Abbott Laboratories
    Inventors: Stephen J. DeMichele, John W. McEwen, Steven M. Wood
  • Patent number: 6248369
    Abstract: A water soluble copper salt, preferably cupric sulfate pentahydrate, is mixed with water. A small quantity of an acidic flocculant is added to the copper sulfate solution to acidify the water and promote dissolving of the copper sulfate in the water. A 25-50% water solution of an acidic flocculant, with or without a cationic polymeric flocculant aid, is prepared and pumped into a processing vessel or tank. The acidified copper sulfate solution is added to the tank and mixed with the acidic flocculant. The algicide-flocculant solution is transported to a municipal water plant and added to raw water in the clarifier to drop out particulates in the incoming water and control algae in the clarifier.
    Type: Grant
    Filed: April 6, 1998
    Date of Patent: June 19, 2001
    Assignee: Bay Chemical and Supply Company
    Inventors: Thomas J. Nier, Tosby L. Linn
  • Patent number: 6242009
    Abstract: Microbicidal formulations are described which are preferably ecologically friendly and non-toxic to mammals, and are highly effective against a broad spectrum of detrimental pathogenic microorganisms. The microbicidal formulation contains complexes having the formula R-M, wherein R is at least one organic chelating moiety and M is at least one metal ion which is microbicidal to at least one microorganism. These complexes can disrupt microorganism activities by penetrating the natural protecting bio-films of such microorganisms through the reaction of the R-group with the organic constituents of these microorganisms while releasing M into their intra-cellular media. Thus, this process exhibits its biocidal activities from the inside-out, contrary to other methods which rely on damaging the protective biofilms.
    Type: Grant
    Filed: April 20, 1999
    Date of Patent: June 5, 2001
    Inventors: Kareem I. Batarseh, Marwan Al-Kayed
  • Patent number: 6197815
    Abstract: Metal amino acid chelates for animals are beneficial for facilitating and promoting growth by increasing desired metallic ion uptake. The present invention is directed to a process for providing an animal fed additive by preparing metal amino acid chelates, and the metal amino acid chelate growth facilitator, promoter and enhancer prepared by the process.
    Type: Grant
    Filed: March 18, 1998
    Date of Patent: March 6, 2001
    Assignee: J.H. Biotech, Inc.
    Inventor: Hsinhung John Hsu
  • Patent number: 6143318
    Abstract: There is provided an antimicrobial composition for combatting infections. The material is a controlled release glass having two or more agents selected from the group consisting of metals, selenium and boron. Preferably the agents are selected from the group consisting of copper, silver, magnesium, zinc, cerium,consisting of copper, silver, magnesium, zinc, cerium, manganese bismuth, selenium and boron. The combinations of copper and silver and of copper and zinc are particularly preferred and exhibit synergist activity. The antimicrobial composition is effective against infections due to Proteus spp.
    Type: Grant
    Filed: August 6, 1997
    Date of Patent: November 7, 2000
    Assignee: Giltech Limited
    Inventors: Thomas Gilchrist, David Michael Healy
  • Patent number: 6139879
    Abstract: The present invention relates to heavy metal chelate compositions, which are used as fungicides and bactericides, and methods of using the compositions. In particular, the present invention relates to a chelate, that is an EDDHA (copper-ethylenediamine-di-o-hydroxyphenylacetic acid), combined with a heavy metal, including iron, tin, zinc, manganese, copper, and combinations thereof.
    Type: Grant
    Filed: August 31, 1999
    Date of Patent: October 31, 2000
    Assignee: Foliar Nutrients, Inc.
    Inventor: John B. Taylor
  • Patent number: 6130244
    Abstract: In its broadest aspect, the present invention is directed to the discovery of immunonutritional products that are useful in reducing the immunological system suppression that results from stress. The stress may be in the form of physical exertion, mental exhaustion, disease states and the like. In one embodiment, the invention relates to a nutritional composition comprising a structured glyceride component and an antioxidant system. This nutritional composition has been shown to be highly effective in reducing immune system down regulation or dysregulation as a result of stress.
    Type: Grant
    Filed: February 25, 1998
    Date of Patent: October 10, 2000
    Assignee: Abbott Laboratories
    Inventors: Stephen J. DeMichele, Steven M. Wood
  • Patent number: 6103768
    Abstract: The invention described here concerns the unique utility of fatty acids and their derivatives to eradicate existing fungal and bacterial infections in plants. Also, described herein are combination treatments whereby fatty acids are used to enhance or augment the activity of fungicides, bactericides, and biological control agents.
    Type: Grant
    Filed: September 8, 1997
    Date of Patent: August 15, 2000
    Assignee: Mycogen Corporation
    Inventors: Steven D. Savage, Steven L. Evans, Robert A. Haygood, Paul S. Zorner, Keith Jones
  • Patent number: 6008238
    Abstract: Disclosed is a stable dilute solution composition of a 3-isothiazolone compound selected from the group consisting of 5-chloro-2-methyl-3-isothiazolone, 2-methyl-3-isothiazolone, 5-chloro-2-ethyl-3-isothiazolone, 2-ethyl-3-isothiazolone, 4,5-dichloro-2-methyl-3-isothiazolone, and mixtures thereof in water having extremely low levels of copper ion and an oxidant.
    Type: Grant
    Filed: February 13, 1998
    Date of Patent: December 28, 1999
    Assignee: Rohm and Haas Company
    Inventors: Beverly Jean El A'mma, John Robert Mattox
  • Patent number: 5997911
    Abstract: A composition and method for reducing the incidence of Poult Enteritis Mortality Syndrome in young turkeys, flushing in mature turkeys, and scours in swine. The composition of the present invention comprises, in combination, a simple copper (II) salt, a hydroxycarboxylic acid, and a buffering agent solubilized within the drinking water of turkeys and/or swine in an antidiarrheal effective dosage as preventative maintenance in avoiding the diarrheal conditions associated with PEMS, flushing, and scours. In a preferred embodiment, the simple copper (II) salt comprises copper sulfate pentahydrate, the hydroxycarboxylic acid comprises anhydrous citric acid, and the buffering, agent comprises ammonium carbonate.
    Type: Grant
    Filed: August 27, 1996
    Date of Patent: December 7, 1999
    Assignee: Brinton Veterinary Supply, Inc.
    Inventors: Gene Brinton, Jackie Brinton Mourning
  • Patent number: 5948443
    Abstract: The present invention pertains generally to the field of Public Health, including the prevention and treatment of coronary heart disease which is currently the first cause of death in the American population. More specifically, the present invention concerns a total modular system of multivitamin and mineral supplementation composed of 7 distinct modules for improving public health by insuring adequate intake of micronutrients needed for disease prevention and protection against nutritional losses and deficiencies due to, for example, lifestyle factors and common inadequate dietary patterns. A module, as used herein throughout, is defined as a separate and distinct combination of vitamin-mineral and other health promoting compounds which are directed to specific target populations. The formulations of the present invention which, when combined in one capsule or tablet or as separate modules, exert a joint and enhancing effect on the major pathogenetic factors involved in the atherosclerotic process.
    Type: Grant
    Filed: February 21, 1997
    Date of Patent: September 7, 1999
    Assignee: Medical Doctor's Research Institute, Inc.
    Inventors: Patricia A. Riley, George Christakis
  • Patent number: 5858993
    Abstract: Methods are provided for preparing compositions suitable for protecting irritated or damaged skin from further oxidative and biochemical damage and thus permitting natural healing processes to progress, for accelerating the rate of healing of burns and surgical wounds, and for increasing the size of hair follicles and the rate of hair growth. The compositions generally comprise precipitates formed by the complexation of starch of various plants with ionic transition metals, such as copper(II) and tin(II) salts.
    Type: Grant
    Filed: September 13, 1996
    Date of Patent: January 12, 1999
    Assignee: Skin Biology, Inc.
    Inventor: Loren R. Pickart
  • Patent number: 5855654
    Abstract: Disclosed is a method of inhibiting the growth of marine organisms on a marine structure, by applying dihydropyridazinone and pyridazinone compounds onto or into the marine structure. These compounds may be directly incorporated into the marine structure during manufacture, directly applied to the structure, or applied to the structure by means of a coating.
    Type: Grant
    Filed: December 9, 1997
    Date of Patent: January 5, 1999
    Assignee: Rohm and Haas Company
    Inventors: Gary Lewis Willingham, Samuel Eugene Sherba, Barry Clifford Lange, Enrique Luis Michelotti
  • Patent number: 5853766
    Abstract: Wood preservatives contain a copper compound, an alkanolamine, a triazole, an emulsifier and/or a phosphonium compound and are used for impregnating wood.
    Type: Grant
    Filed: January 21, 1997
    Date of Patent: December 29, 1998
    Assignee: Dr. Wolman GmbH
    Inventors: Reimer Goettsche, Hans-Volker Borck
  • Patent number: 5846305
    Abstract: A liquid wood preservative solution includes sufficient quantities of a copper compound known as having beneficial effects as a wood preservative to provide a copper metal content of between 1% and 6% by weight. At least 6% by weight of a liquid amine solvent is provided for every 1% of the copper metal. The liquid wood preservative solution includes between 10% and 30% by weight of a boron compound known as having beneficial effects as a wood preservative. At least 1% by weight of glycol is provided for every 1% of the boron compound.
    Type: Grant
    Filed: October 23, 1996
    Date of Patent: December 8, 1998
    Assignee: Michael Wall & Sons Enterprises Ltd.
    Inventor: John Payzant
  • Patent number: 5795374
    Abstract: A coating composition comprising a rosin compound, a polymer containing organosilyl ester groups, and an antifoulant as essential components is disclosed. This rosin-based coating composition gives a coating film which forms no residue layer on the surface thereof over long-term immersion, is hence free from physical defects such as cracks and peeling and capable of maintaining a sufficiently high rate of film erosion and preventing the attachment of marine organisms over a long period of time has satisfactory suitability for recoating, and has the satisfactory ability to prevent marine-organism attachment over the out-fitting period.
    Type: Grant
    Filed: April 15, 1997
    Date of Patent: August 18, 1998
    Assignee: NOF Corporation
    Inventors: Masayasu Itoh, Shigeo Fukuda, Yoshihisa Kawakami, Yoshiro Matsubara, Yasushi Kawamura, Shigeru Masuoka, Yoshihiro Honda
  • Patent number: 5634967
    Abstract: The instant invention concerns a wood preservative composition comprising a synergistically effective amount of (a) a cuprammonium compound and (b) tebuconazole to preserve wood.
    Type: Grant
    Filed: June 5, 1995
    Date of Patent: June 3, 1997
    Assignee: Hickson International PLC
    Inventors: Gareth Williams, Judith A. Cornfield, Janet Brown, Neil P. Ryan
  • Patent number: 5628986
    Abstract: Disclosed are oral compositions such as toothpastes, mouthrinses, liquid dentifrices, lozenges and gums containing at least one phosphate derivative and a copper source.
    Type: Grant
    Filed: April 16, 1996
    Date of Patent: May 13, 1997
    Assignee: The Procter & Gamble Company
    Inventors: Lowell A. Sanker, James G. Upson
  • Patent number: 5614550
    Abstract: Compounds of formula (I) are provided: ##STR1## wherein: R.sup.1 represents an alkyl group; or a group of formula (II), (III), (IV) or (V): ##STR2## and wherein the groups R.sup.2, R.sup.3, R.sup.4 and R.sup.5 are hydrogen or various organic groups; and pharmaceutically acceptable salts thereof; as well as methods for the preparation of such compounds and their use in the treatment and prophylaxis of hypercholesteremia and arteriosclerosis.
    Type: Grant
    Filed: February 27, 1996
    Date of Patent: March 25, 1997
    Assignee: Sankyo Company, Limited
    Inventors: Akira Yoshida, Koza Oda, Sadao Ishihara, Fujio Saito, Hiroyuki Koike, Teiichiro Koga, Eiichi Kitazawa, Hiroshi Kogen, Ichiro Hayakawa
  • Patent number: 5612142
    Abstract: Wood and other cellulose-based products are preserved with a water-based treating solution containing a phenolic resin prepolymer such as phenol formaldehyde resin prepolymer, a resorcinol formaldehyde resin prepolymer and water. The treatment is carried out by exposing the wood or other cellulose-based product, while submerged in the treating solution, to one or more cycles of reduced pressure (i.e. vacuum) and elevated pressure.
    Type: Grant
    Filed: October 23, 1995
    Date of Patent: March 18, 1997
    Assignee: Polymer Wood Processors, Inc.
    Inventor: Jean Lewis, deceased
  • Patent number: 5534529
    Abstract: Compounds of formula (I) are provided: ##STR1## wherein: R.sup.1 represents an alkyl group; or a group of formula (II), (III), (IV) or (V): ##STR2## and wherein the groups R.sup.2, R.sup.3, R.sup.4 and R.sup.5 are hydrogen or various organic groups; and pharmaceutically acceptable salts thereof; as well as methods for the preparation of such compounds and their use in the treatment and prophylaxis of hypercholesteremia and arteriosclerosis.
    Type: Grant
    Filed: June 28, 1994
    Date of Patent: July 9, 1996
    Assignee: Sankyo Company, Limited
    Inventors: Akira Yoshida, Koza Oda, Sadao Ishihara, Takashi Kasai, Fujio Saito, Hiroyuki Koike, Teiichiro Koga, Eiichi Kitazawa, Hiroshi Kogen, Ichiro Hayakawa
  • Patent number: 5527384
    Abstract: The instant invention concerns a wood preservative composition comprising a synergistically effective amount of (a) a cuprammonium compound and (b) tebuconazole to preserve wood.
    Type: Grant
    Filed: April 4, 1994
    Date of Patent: June 18, 1996
    Assignee: Hickson International, Plc
    Inventors: Gareth Williams, Judith A. Cornfield, Janet Brown, Neil P. Ryan
  • Patent number: 5496539
    Abstract: Disclosed are oral compositions such as toothpastes, mouth-rinses, liquid dentifrices, lozenges and gums containing copper bis-glycinate.
    Type: Grant
    Filed: October 11, 1994
    Date of Patent: March 5, 1996
    Assignee: The Procter & Gamble Company
    Inventors: Michael J. Mobley, Michael F. Lukacovic, Peter A. Padolik, Gregory Berry
  • Patent number: 5470586
    Abstract: A method of controlling the attachment of organisms to an underwater surface is disclosed. The method comprises contacting the organisms with a compound of Formula I ##STR1## wherein R.sub.1, R.sub.2 and R.sub.3 are each independently hydrogen, C.sub.1 -C.sub.3 alkyl, C.sub.1 -C.sub.3 alkoxy, halogen, or hydroxyl. Antifouling coatings and cementitious compositions containing a compound of Formula I are also disclosed.
    Type: Grant
    Filed: April 11, 1994
    Date of Patent: November 28, 1995
    Assignee: Duke University
    Inventor: Donald J. Gerhart
  • Patent number: 5462589
    Abstract: The invention is directed to synergistic biocidal compositions that combine a copper salt and an organic biocide selected from the group of tribromophenol, its salts and chelates, and sodium-omadine, its salts and chelates. Wood treated with the preservative compositions have improved fungi resistance.
    Type: Grant
    Filed: February 22, 1994
    Date of Patent: October 31, 1995
    Assignee: Mississippi Forest Products Laboratory
    Inventors: Darrel D. Nicholas, Tor P. Schultz
  • Patent number: 5460751
    Abstract: Aqueous wood treating compositions, containing compounds which contain elements selected from copper, chromium and arsenic and oxyalkylene polymer additives, provide improved stability to CCA solutions containing additives. In addition, the compositions of the present invention have been found to retard hardening effects associated with wood treated with commercial CCA solutions.
    Type: Grant
    Filed: September 2, 1993
    Date of Patent: October 24, 1995
    Assignee: Union Carbide Chemicals & Plastics Technology Corporation
    Inventors: Frank M. S. Ma, Marcel Ayotte
  • Patent number: 5444093
    Abstract: Wood preservatives contain a copper salt, a polyamine and a fatty amine and are used for preserving wood from fungi and termites.
    Type: Grant
    Filed: November 3, 1993
    Date of Patent: August 22, 1995
    Assignee: Dr. Wolman GmbH
    Inventors: Reimer Goettsche, Hans-Volker Borck
  • Patent number: 5439512
    Abstract: A coating varnish composition comprising (A) a polymer obtained by polymerizing one or more unsaturated carboxylic acids (a) with one or more unsaturated monomers (b), and (B) at least one additive selected from triazole derivatives, thiadiazole derivatives, and benzothiazole derivatives, and an antifouling coating composition comprising (i) said coating varnish and (ii) an antifouling agent containing a copper compound as a major component, do not show a danger of organotin copolymers, but provide a coating excellent in coating consuming properties and antifouling properties for a long period of time without causing gelation when mixed with a copper compound.
    Type: Grant
    Filed: January 12, 1994
    Date of Patent: August 8, 1995
    Assignee: Hitachi Chemical Company, Ltd.
    Inventors: Koichi Kamijima, Seiji Tai, Hiroyuki Tanaka
  • Patent number: 5439511
    Abstract: A coating varnish composition comprising (A) a polymer obtained by polymerizing (a) at least one unsaturated acid anhydride and (b) at least one other unsaturated monomer, and (B) at least one additive selected from triazole derivatives, benzothiazole derivatives, thiadiazole derivatives, polyethers and carboxylic acid anhydride derivatives, is capable of forming a coating which has no danger of poisoning like the organotin copolymers, shows a coating consuming property and antifouling performance comparable with those of the organotin copolymers and does not gel even when mixed with a copper compound.
    Type: Grant
    Filed: January 12, 1994
    Date of Patent: August 8, 1995
    Assignee: Hitachi Chemical Company, Ltd.
    Inventors: Hiroyuki Tanaka, Seiji Tai, Koichi Kamijima
  • Patent number: 5426121
    Abstract: Liquid wood preservation formulations comprise a liquid solvent and a complex dissolved therein which is formed by the reaction of a compound containing a copper cation and an alkoxylated diamine, preferably containing at least one fatty alkyl group, such as an alkoxylated diamine wherein the alkoxylation is either ethoxylation or propoxylation.
    Type: Grant
    Filed: October 4, 1994
    Date of Patent: June 20, 1995
    Assignee: Akzo Nobel N.V.
    Inventor: John P. Bell
  • Patent number: 5399190
    Abstract: A wood preservative composition including a mixture of two or more metallic soaps of long chain unsaturated fatty acids, which soaps have a metallic component selected from the group consisting of copper, zinc, chromium, iron, antimony, tin, cobalt, nickel, arsenic, boron, lead, magnesium, potassium and sodium, and a fatty acid component selected from two or more of the group consisting of oleic acid, linoleic acid, and linolenic acid, the composition being such that the ratio by mass of metallic soap of oleic acid:metallic soap of linoleic acid:metallic soap of linolenic acid is about 20-29:15-70:0-47.
    Type: Grant
    Filed: May 3, 1993
    Date of Patent: March 21, 1995
    Assignees: Shell South Africa (Pty.) Ltd., CSIR, Shell Research Ltd.
    Inventors: Wilhelm E. Conradie, Andrew J. Pendlebury, Antonio Pizzi, Denise Conradie
  • Patent number: 5385934
    Abstract: Disclosed herein are copper based fungicidal and bactericidal compositions having enhanced activity against fungi and bacteria, methods of using such compositions as well as methods for increasing the effectiveness of the copper based fungicidal and/or bactericidal compounds employed in such compositions. An aggregation inhibiting salt is included within these compositions to prevent aggregate and/or sediment formation upon the addition of Fe.sup.+3 to the composition.
    Type: Grant
    Filed: April 12, 1993
    Date of Patent: January 31, 1995
    Assignee: The Regents of the University of California
    Inventors: Milton N. Schroth, Yung-Ann Lee, Mavis D. Chong
  • Patent number: 5385724
    Abstract: Methods and compositions are disclosed for enhancing .sup.19 F magnetic resonance imaging which utilize trifluoromethyl derivatives of iodinated X-ray contrast media. Typical magnetic resonance contrast media within the scope of the present invention include bis(trifluoromethyl)benzene derivatives, tris(trifluoromethyl)benzene derivatives, tetrakis(trifluoromethyl)benzene derivatives, and other related trifluoromethylated benzene derivatives.
    Type: Grant
    Filed: March 4, 1994
    Date of Patent: January 31, 1995
    Assignee: Mallinckrodt Medical, Inc.
    Inventors: David H. White, Steven R. Woulfe, Youlin Lin, Mills T. Kneller
  • Patent number: 5385933
    Abstract: A composition and a method for inhibiting cellular proliferation, such as the abnormal cellular proliferation characteristic of cancer cells. The method comprises the administration to a mammal, in particular a human, of an effective amount of S-(methylthio)-DL-homocysteine or S-(methylthio)-L-homocysteine, either simultaneously or sequentially, with an effective amount of a copper chelate such that an effective amount of an inhibitory complex forms in the mammal between the S-(methylthio)-homocysteine and the copper of the cooper chelate. The inhibitory complex is capable of inhibiting the proliferation of cells contacted by the inhibitory complex.
    Type: Grant
    Filed: June 19, 1992
    Date of Patent: January 31, 1995
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventors: Marco Rabinovitz, Joyce M. Fisher
  • Patent number: 5364649
    Abstract: The activity of antimicrobial compounds selected from isothiazolones and compounds which release formaldehyde is enhanced with a metal complex of a lower alkanolamine, particularly copper (cupric) triethanolamine. The enhancement is particularly useful in metalworking fluids.
    Type: Grant
    Filed: March 30, 1993
    Date of Patent: November 15, 1994
    Inventors: Leonard A. Rossmoore, Harold W. Rossmoore
  • Patent number: 5352444
    Abstract: Biowaste treatment agents for treating biowastes in a manner which: (a) keeps noxious and toxic substances from being released from the biowaste, and (b) neutralizes such substances released during the course of stabilizing the biowaste. The treatment agents include a surfactant in an amount of from 1.0 to 99 percent of the treatment agent, a metal component in an amount from 0.5 to 85 percent of the treatment agent, the metal component including a source of zinc, or copper, or a combination of copper with aluminum or iron, and an aldehyde in an amount from 0.1 to 80 percent of the treatment agent.
    Type: Grant
    Filed: May 19, 1992
    Date of Patent: October 4, 1994
    Inventors: James P. Cox, R. W. Duffy Cox
  • Patent number: 5342438
    Abstract: This invention discloses a non-water dilutable remedial wood preservative containing 1/2 to 10 parts copper derived from amine-inorganic copper complexes, combined with sodium borate or sodium fluoride, or a combination thereof, in a ratio of 2 to 120 parts of the sodium salt for each part of copper in the preservative. This invention also discloses the improvement in copper penetration into the wood which occurs when the amine-inorganic copper complexes are combined with sodium borate and/or sodium fluoride, and a novel method of thickening these compositions.
    Type: Grant
    Filed: January 24, 1994
    Date of Patent: August 30, 1994
    Inventor: Michael H. West
  • Patent number: 5342437
    Abstract: The present invention relates generally to paint and paint base and, more specifically, to a process and composition for providing a stable gel-free dispersion of zinc pyrithione plus cuprous oxide in paint. In accordance with the process of the present invention, the paint or paint base contains a carboxylic acid in order to impart desired gelation inhibition to the paint.
    Type: Grant
    Filed: October 15, 1993
    Date of Patent: August 30, 1994
    Assignee: Olin Corporation
    Inventors: David F. Gavin, Rahim Hani, Craig Waldron, Douglas A. Farmer, Jr.
  • Patent number: 5336304
    Abstract: The present invention describes in detail new environmentally safe marine vessel hull coating formulations for all outer surfaces of all marine vessel surfaces specifically designed to fully comply with all existing and anticipated environmental regulations. These formulations absolutely prevent water ingress, galvanic corrosion, wood decay, worm ingress, flex to accommodate to hull motions and protect against impact damages and may last for 20 years of the economic life of the marine vessel. These inventive formulations embody specific encapsulation techniques that allow aluminum and large steel hulls to now use these advanced coating products since they do not contain any toxins or co-toxins thereby eliminating the concern about the existing TBT exemptions. The specific materials which are applied to the marine vessel hulls are specified and include an epoxy adhesive resin mixed with copper powder and a thixotropic agent to cause the coating to maintain its shape and configuration while curing.
    Type: Grant
    Filed: July 28, 1992
    Date of Patent: August 9, 1994
    Assignee: Cresco, Inc., SA.
    Inventor: Graham C. Andoe
  • Patent number: 5304237
    Abstract: A water-soluble chromium-free wood preservative comprising at least one copper salt and an alkanolamine and a polymeric quaternary ammonium borate formed by simultaneous reaction of (A) an amine selected from the group consisting of ##STR1## wherein R.sub.1 is alkyl or alkenyl of 8 to 22 carbon atoms or when R.sub.2 and R.sub.3 are --(C.sub.2 H.sub.4 O).sub.x --H or --(C.sub.3 H.sub.6 O).sub.x --H, R.sub.1 is alkyl of 1 to 22 carbon atoms, R.sub.2 is selected from the group consisting of hydrogen, alkyl of 1 to 22 carbon atoms, --(C.sub.2 H.sub.4 O).sub.x --H, --(C.sub.3 H.sub.6 O).sub.x --H and --CH.sub.2 --CH.sub.2 --NH.sub.2, R.sub.3 is selected from the group consisting of hydrogen, --(C.sub.2 H.sub.4 O).sub.x --H, --(C.sub.3 H.sub.6 O).sub.x --H and CH.sub.2 --CH.sub.2 --CH.sub.2 NH.sub.2, R.sub.4 and R.sub.6 are individually alkyl of 1 to 4 carbon atoms or --(CH.sub.2 H.sub.4 O).sub.x --H or --(C.sub.3 H.sub.6 O).sub.x --H, R.sub.5 and R.sub.2 are individually --(C.sub.2 H.sub.4 O).sub.x --H or -- (.
    Type: Grant
    Filed: January 21, 1993
    Date of Patent: April 19, 1994
    Assignee: Rutgerswerke Aktiengesellschaft AG
    Inventors: Volker Barth, Helmut Hartner
  • Patent number: 5276029
    Abstract: Wood preservatives contain a copper salt, a polyamine and a fatty amine and are used for preserving wood from fungi and termites.
    Type: Grant
    Filed: November 1, 1990
    Date of Patent: January 4, 1994
    Assignee: Dr. Wolman GmbH
    Inventors: Reimer Goettsche, Hans-Volker Borck
  • Patent number: RE36798
    Abstract: The instant invention concerns a wood preservative composition comprising a synergistically effective amount of (a) a cuprammonium compound and (b) tebuconazole to preserve wood.
    Type: Grant
    Filed: November 12, 1998
    Date of Patent: August 1, 2000
    Assignee: Hickson International, Plc
    Inventors: Gareth Williams, Judith A. Cornfield, Janet Brown, Neil P. Ryan