Additional C=o Bonded Directly To Urea Nitrogen Patents (Class 514/594)
  • Patent number: 5981596
    Abstract: There is provided a method for the control of resistant populations of Lepidoptera: Olethreutidae such as Cydia pomonella (L.), Laspeyresia pomonella (L.) Grapholitha molesta (Busck), and the like and the protection of fruit crops therefrom which comprises contacting said Lepidoptera with a toxic amount of flufenoxuron.
    Type: Grant
    Filed: January 5, 1998
    Date of Patent: November 9, 1999
    Assignee: American Cyanamid Company
    Inventor: Emmanuel Thienpont
  • Patent number: 5973008
    Abstract: The present invention relates to a method for controlling domestic pests using 2-chloro-N-[{(4'-chloro-2-methoxy[1,1'-biphenyl]4-yl)amino}carbonyl]benzam ide. The benzamide is particularly effective against termites and is suitable for use in baits.
    Type: Grant
    Filed: April 18, 1997
    Date of Patent: October 26, 1999
    Assignee: FMC Corporation
    Inventors: Alan R. DeAngelis, Jane A. Dybas, John A. Dixson
  • Patent number: 5952386
    Abstract: The present invention provides dihalopropene compounds of the general formula: ##STR1## wherein R.sub.1 is C.sub.1 -C.sub.10 alkyl or the like; L is C(.dbd.O)NH or the like; R.sub.2, R.sub.3 and R.sub.4 are independently halogen or the like; R.sub.5, R.sub.6 and R.sub.7 are independently hydrogen or the like; m is an integer of 0 to 4; n is an integer of 0 to 2; X is chlorine or the like; Y is oxygen or the like; and Z is oxygen or the like, which have excellent insecticidal activity so that they are satisfactorily effective for the control of noxious insects.
    Type: Grant
    Filed: September 24, 1997
    Date of Patent: September 14, 1999
    Assignee: Sumitomo Chemical Company, Limited
    Inventors: Sanshiro Matsuo, Taro Hirose, Keiichi Izumi, Masaya Suzuki, Noriyasu Sakamoto, Kazunori Tsushima, Shigeru Saito, Hirotaka Takano
  • Patent number: 5945453
    Abstract: Compounds of the formula (I) ##STR1## wherein R.sup.1 and R.sup.2 are H, methyl, or ethyl, and wherein at least one of R.sup.1 and R.sup.2 is methyl or ethyl, are disclosed to control cockroaches.
    Type: Grant
    Filed: October 31, 1997
    Date of Patent: August 31, 1999
    Assignee: Dow AgroSciences LLC
    Inventors: Ronald J. Sbragia, George W. Johnson, Laura L. Karr, Jeff M. Edwards, Brian M. Schneider
  • Patent number: 5910323
    Abstract: This invention provides a novel aqueous pesticide formulation having a fungicidal bicarbonate-containing inorganic salt ingredient which enhances the efficacy of an insecticidal ingredient for treatment of cultivated crops. An invention pesticide formulation also contains a water-soluble organic compound which functions as a compatibility enhancing ingredient in the aqueous pesticide formulation, and improves the spreadability and adhesiveness of the composition ingredients when applied to foliage.
    Type: Grant
    Filed: October 21, 1993
    Date of Patent: June 8, 1999
    Assignee: Church & Dwight Co., Inc.
    Inventors: M. Stephen Lajoie, Amy L. Joseph, Keith A. Jones, Anthony E. Winston
  • Patent number: 5886221
    Abstract: Compounds of the formula (I) ##STR1## wherein R.sup.1 and R.sup.2 are H, methyl, or ethyl, have unexpected activity against cockroaches, ants, fleas, and termites. Compounds wherein at least one of R.sup.1 and R.sup.2 is methyl or ethyl are novel.
    Type: Grant
    Filed: November 3, 1997
    Date of Patent: March 23, 1999
    Assignee: Dow AgroSciences LLC
    Inventors: Ronald J. Sbragia, George W. Johnson, Laura L. Karr, Jeff M. Edwards, Brian M. Schneider
  • Patent number: 5854288
    Abstract: The use of compounds of the formula I ##STR1## in which R.sup.1 -R.sup.6, A, B und X have the meaning given in detail in the description, for controlling house dust mites.The miticide has a high miticidal effect against house dust mites of Tyrophagus, Dermatophagoides, Cheyletidae, etc. and is harmless to humans and beasts. It is effective not only in exterminating such house dust mites but also in preventing from them.
    Type: Grant
    Filed: August 2, 1996
    Date of Patent: December 29, 1998
    Assignee: Hoechst Schering AgrEvo GmbH
    Inventors: Yoshio Katsuda, Hans-Herbert Schubert, Hilmar Mildenberger, Stefan Schnatterer, Herbert Stark
  • Patent number: 5837734
    Abstract: This invention relates to the use of acyl urea compounds for the treatment or prophylaxis of Coccidioides immitis infections in warm-blooded animals. The invention has particular application in the treatment, prophylaxis or reduction of coccidioidomycosis.
    Type: Grant
    Filed: May 1, 1996
    Date of Patent: November 17, 1998
    Assignee: Novartis Corporation
    Inventors: Robert C. Bartsch, Russell T. Greene
  • Patent number: 5811461
    Abstract: Compounds of formula (I): ##STR1## wherein R.sup.1 is --CF=CFCF.sub.3 or --CF.sub.2 CF=CFCF.sub.3 are useful in control of cockroaches, ants, fleas, or termites.
    Type: Grant
    Filed: October 31, 1997
    Date of Patent: September 22, 1998
    Assignee: Dow AgroSciences LLC
    Inventors: Ronald E. Hackler, George W. Johnson, John M. Owen
  • Patent number: 5776981
    Abstract: A method of systemically controlling endoparasites and ectoparasites of warm-blooded animals by orally or percutaneously administering to the animal a parasiticidally effective amount of an acyl urea compound.
    Type: Grant
    Filed: April 21, 1995
    Date of Patent: July 7, 1998
    Assignee: Novartis Corporation
    Inventors: Michael Fred Potter, George Lorton Rotramel, Andrew James Caruso, David Teh-Wei Chou, Paul Alfred Cain
  • Patent number: 5776982
    Abstract: A method of systemically controlling endoparasites and ectoparasites of warm-blooded animals by orally or percutaneously administering to the animal a parasiticidally effective amount of an acyl urea compound.
    Type: Grant
    Filed: May 31, 1995
    Date of Patent: July 7, 1998
    Assignee: Novartis Corporation
    Inventors: Michael Fred Potter, George Lorton Rotramel, Andrew James Caruso, David Teh-Wei Chou, Paul Alfred Cain
  • Patent number: 5728719
    Abstract: The present invention is a method for controlling ectoparasites. More particularly, the invention relates to a method of treatment in which the warm blooded animal is dosed with an ovicidally effective amount of a heterocyclic nitrogen compound selected from the group represented by the formula: ##STR1## wherein R.sub.1, is either one of the following groups: ##STR2## in which R.sub.7, R.sub.8, R.sub.9, R.sub.10, R.sub.11, R.sub.12, R.sub.13, R.sub.14, R.sub.15, R.sub.16, and R.sub.17 are, the same or different, each a hydrogen atom, a halogen atom, a C.sub.1 -C.sub.4 alkoxy group, a C.sub.1 -C.sub.4 alkylthio group, a trifluoro methyl group or a vitro group, R.sub.18, R.sub.19, R.sub.20 and R.sub.21 are, the same or different, each a hydrogen atom or a methyl group, k is an integer of 0 to 1 and 1 is an integer of 0 to 3; R.sub.2 and R.sub.3 are, the same or different, each a hydrogen atom, a halogen atom or a methyl group; R.sub.4 is a halogen atom or a methyl group; R.sub.5 and R.sub.
    Type: Grant
    Filed: March 14, 1995
    Date of Patent: March 17, 1998
    Assignee: Virbac, Inc.
    Inventor: Thomas A. Miller
  • Patent number: 5691383
    Abstract: Method of using specific acyl urea compounds as termiticides. The compounds are unusually non-repellant to termites and active at low dosages.
    Type: Grant
    Filed: June 26, 1996
    Date of Patent: November 25, 1997
    Assignee: DowElanco
    Inventors: Ellen M. Thoms, Ronald J. Sbragia
  • Patent number: 5637298
    Abstract: 2-naphthalenemethanol [Chemical Abstracts registry no. 1592-38-7] produces a high degree of trail-following activity in termites. The attractant 2-naphthalenemethanol and certain derivatives increase bait acceptance by termites, improving the ability of termite baits to kill colonies, allowing lower amounts of toxicant to be used, or both.
    Type: Grant
    Filed: June 14, 1996
    Date of Patent: June 10, 1997
    Assignee: Board of Supervisors of Louisiana State University and Agricultural and Mechanical College
    Inventor: John C. Stowell
  • Patent number: 5607977
    Abstract: Compounds of the formula ##STR1## wherein R.sub.1 is fluorine, chlorine, bromine or iodine; and A is 2,6-difluorophenyl, 2-chlorophenyl, 2-chloro-6-fluorophenyl, 2,6-dichlorophenyl or 2-fluorophenyl,with the proviso that when R.sub.1 is chlorine, A is other than 2,6-dichlorophenyl, useful as pesticides.
    Type: Grant
    Filed: October 22, 1991
    Date of Patent: March 4, 1997
    Assignee: Shell Agrar GmbH & Co. KG
    Inventors: Heinz-Manfred Becher, Christo Drandarevski, Rudolf Mengel, Walter Ost
  • Patent number: 5583089
    Abstract: This invention provides a dry blend pesticide composition which contains a fungicidal bicarbonate salt ingredient, and a spreader-sticker ingredient which is a crystalline clathrate complex of a urea constituent and a normally liquid spreader sticker constituent such as a nonionic surfactant. In a preferred embodiment all of the composition ingredients are water-soluble, and the composition is readily dispersible in an aqueous medium to form a sprayable pesticide solution.
    Type: Grant
    Filed: May 9, 1995
    Date of Patent: December 10, 1996
    Assignee: Church & Dwight Co., Inc.
    Inventor: Anthony E. Winston
  • Patent number: 5556883
    Abstract: Method of using specific acyl urea compounds as termiticides. The compounds are unusually non-repellant to termites and active at low dosages.
    Type: Grant
    Filed: May 11, 1995
    Date of Patent: September 17, 1996
    Assignee: DowElanco
    Inventors: Ellen M. Thoms, Ronald J. Sbragia
  • Patent number: 5527823
    Abstract: A formulation suitable for spraying or for dilution with water to form a sprayable preparation, the formulation comprising an active ingredient, optionally a carrier or solvent for the active ingredient, an emulsifier and an evaporation retardant, characterized in that the formulation satisfies formula ##EQU1## where L is less than or equal to 15, A=700376, B=-1.51, C=0.8472, M.sub.oil is the weighted average relative molar mass of the oil phase M.sub.retardant is the weighted average relative molar mass of the retardant, and X=(M.sub.oil) 1.8/Y, where Y is the molar solubility ration of the formulation, defined as the minimum number of moles of the oil phase which will dissolve the retardant, divided by the number of moles of retardant, provided that, in the formula above, any solvent which has no liquid phase at 27.degree. C. at atmospheric pressure is excluded. The formulation may comprise a pesticide or herbicide. The action of the evaporation retardant is improved.
    Type: Grant
    Filed: February 8, 1994
    Date of Patent: June 18, 1996
    Assignee: Roussel UCLAF
    Inventors: Robert Martin, David A. Jeffries, Denise K. North, John M. Groome, Peter L. Crampton, Andrew J. Huson
  • Patent number: 5432148
    Abstract: This invention provides a fungicide composition which is capable of in situ generation of ammonium bicarbonate when applied to plant foliage in the form of an aqueous dispersion. The constituents include (1) an ingredient such as urea which slow-releases ammonia under aqueous alkaline pH conditions; and (2) an alkali metal bicarbonate ingredient which imparts alkalinity to the aqueous dispersion, and provides bicarbonate ions for combination with the released ammonium ions. A spreader-sticker ingredient is included to maintain the ingredients in contact with plant foliage over an extended period after application.
    Type: Grant
    Filed: December 7, 1994
    Date of Patent: July 11, 1995
    Assignee: Church & Dwight Co., Inc.
    Inventor: Anthony E. Winston
  • Patent number: 5425952
    Abstract: This invention provides a fungicide composition which is capable of in situ generation of ammonium bicarbonate when applied to plant foliage in the form of an aqueous dispersion. The constituents include (1) an ingredient such as urea which slow-releases ammonia under aqueous alkaline pH conditions; and (2) an alkali metal bicarbonate ingredient which imparts alkalinity to the aqueous dispersion, and provides bicarbonate ions for combination with the released ammonium ions. A spreader-sticker ingredient is included to maintain the ingredients in contact with plant foliage over an extended period after application.
    Type: Grant
    Filed: October 13, 1993
    Date of Patent: June 20, 1995
    Assignee: Church & Dwight Co., Inc.
    Inventor: Anthony E. Winston
  • Patent number: 5423905
    Abstract: The invention relates to a formulation for protecting keratinous material from attack by pests that feed on keratin, comprising (A) at least one diphenylurea of formula ##STR1## wherein R.sub.1 is hydrogen or 4-chlorophenoxy-6-sulfonate,R.sub.2 is hydrogen or chloro,R.sub.3 is chloro or trifluoromethyl,R.sub.4 is hydrogen or chloro, andR.sub.5 is hydrogen or trifluoromethyl, and(B) at least one glycol, and to a process for protecting keratinous material against attack by pests that feed on keratin with the novel formulation.
    Type: Grant
    Filed: July 18, 1994
    Date of Patent: June 13, 1995
    Assignee: Ciba-Geigy Corporation
    Inventor: Werner Fringeli
  • Patent number: 5420163
    Abstract: A method of systemically controlling endoparasites and ectoparasites of warm-blooded animals by orally or percutaneously administering to the animal a parasiticidally effective amount of an acyl urea compound.
    Type: Grant
    Filed: August 3, 1992
    Date of Patent: May 30, 1995
    Assignee: Ciba-Geigy
    Inventors: Michael F. Potter, George L. Rotramel, Andrew J. Caruso, David T. Chou, Paul A. Cain
  • Patent number: 5416102
    Abstract: A method of treating fleas on dogs and cats by orally administering a larvicidally or ovicidally effective amount of flea growth inhibiting benzoylurea.
    Type: Grant
    Filed: June 27, 1994
    Date of Patent: May 16, 1995
    Assignee: Ciba-Geigy Corporation
    Inventors: Sharron H. Barnett, Roland H. Johnson, Douglas I. Hepler, Manfred Boger
  • Patent number: 5288756
    Abstract: The invention relates to novel substituted N-benzoyl-N'-3,5-dichlorohexafluoropropyloxyphenylureas of the formula ##STR1## wherein R.sub.1 is hydrogen or fluorine and R.sub.2 is fluorine or chlorine, and to salts thereof; to processes and intermediates for the preparation of these compounds and to compositions containing the novel compounds for controlling insects, representatives of the order Acarina and slugs and snails, in particular plant-destructive insects.
    Type: Grant
    Filed: August 5, 1992
    Date of Patent: February 22, 1994
    Assignee: Ciba-Geigy Corporation
    Inventor: Jozef Drabek
  • Patent number: 5288758
    Abstract: New urea derivatives corresponding to the general formula 1 ##STR1## in which: R.sup.1 represents a C.sub.1 -C.sub.4 alkyl group;R.sup.2 represents:a C.sub.5 -C.sub.7 cycloalkyl groupa cycloalkylmethyl group in which the cycloalkyl radical contains from 5 to 7 carbon atomsa benzyl groupa benzyl group in which the aromatic ring bears a C.sub.1 -C.sub.4 alkyl group, a C.sub.1 -C.sub.4 alkoxy group, a halogen atom or a nitro group;A represents an oxygen atom or a methylene radical;n represents 1 or 2;X represents an oxygen or sulfur atom;B represents a direct bond, a methylene radical or a carbonyl radical;as well as the therapeutically acceptable salts of these molecules.The invention also relates to the application of the compounds of general formula 1 in therapy, and to the preparation processes.
    Type: Grant
    Filed: July 22, 1992
    Date of Patent: February 22, 1994
    Assignee: Pierre Fabre Medicament
    Inventors: Jean-Louis Vidaluc, Dennis Bigg
  • Patent number: 5264213
    Abstract: A highly active water-dispersible pesticide formulation is prepared by dissolving at least a part of a benzoyl phenyl urea series insecticidal compound in an organic solvent, contacting the so obtained mixture with a carrier material, and pulverizing the resulting mixture. The pesticidal formulation obtained has higher pesticidal activity than formulations prepared by a conventional dry methods.
    Type: Grant
    Filed: July 7, 1989
    Date of Patent: November 23, 1993
    Assignee: DowElanco
    Inventors: Tetsuya Shibahara, Naohiko Kondo, Jun Kato
  • Patent number: 5210100
    Abstract: The invention relates to novel N-[3-halo-4-(hexafluoropropoxy)-5-trifluoromethyl]phenyl-N'-benzoylureas of the formula ##STR1## wherein R.sub.1 is hydrogen or halogen and R.sub.2 and R.sub.3 are halogen, to a process and intermediate for the preparation of these compounds, and to compositions containing them for use in pest control, in particular for controlling insects and representatives of the order Acarina that attack plants and animals. The novel compounds exhibit in particular larvicidal activity.
    Type: Grant
    Filed: October 25, 1989
    Date of Patent: May 11, 1993
    Assignee: Ciba-Geigy Corporation
    Inventor: Josef Ehrenfreund
  • Patent number: 5177110
    Abstract: Parenterally injectable compositions for controlling parasites, which compositions contain from 0.1 to 10% of a benzoylurea as active ingredient, from 0.1 to 60% of a 1-substituted azacycloalkan-2-one, from 2 to 90% of a physiologically tolerable surfactant or mixture of surfactants and, if appropriate, as stabilizing component, from 0.05 to 15% of an acid or a buffer mixture and add 100% of a physiologically tolerable hydrophilic solvent or mixture of solvents or a mixture of physiologically tolerable hydrophilic and lipophilic solvents.
    Type: Grant
    Filed: April 22, 1991
    Date of Patent: January 5, 1993
    Assignee: Ciba-Geigy Corporation
    Inventors: Walter Oechslein, Jean-Claude Gehret, Ernst Hess, Sabine Rossow
  • Patent number: 5169846
    Abstract: A non-aqueous micellar solution, for use in animal health, of one or more non water-soluble Anthelmintics and or insect growth regulators in a polyethoxylated oil or fat surfactant and one or more co-solvents chosen from a group comprising dimethyl sulphoxide (DMSO), N-methyl pyrollidone (NMP), tetraglycol (TG) and propylene glycol (PG).
    Type: Grant
    Filed: October 11, 1990
    Date of Patent: December 8, 1992
    Inventor: Michael J. Crooks
  • Patent number: 5166180
    Abstract: The present invention relates to a method of treating hematopoietic diseases in warm-blooded living beings. The method is carried out by administering an effective amount of a compound of the formula ##STR1## wherein R.sub.5 represents (a) 1-3 substituents selected from the group consisting of halogen, C.sub.1 -C.sub.6 alkyl, trifluoromethyl, C.sub.1 -C.sub.4 alkoxy, C.sub.1 -C.sub.4 alkylthio, hydroxy, C.sub.2 -C.sub.5 alkanoyloxy, amino, N, N-di(C.sub.1 -C.sub.4) alkylamino and piperidyl; or (b) five fluorine atoms;R.sub.6 represents 1-3 substituents selected from the group consisting of halogen, C.sub.1 -C.sub.4 alkyl, trifluoromethyl, C.sub.1 -C.sub.4 alkoxy, C.sub.1 -C.sub.4 haloalkoxy, cyclohexyloxy, adamantyloxy, hydroxy, amino and N-C.sub.2 -C.sub.5 alkanoylamino;X is oxygen or sulphur, andY is oxygen or sulphur.
    Type: Grant
    Filed: February 27, 1990
    Date of Patent: November 24, 1992
    Assignee: Duphar International Research B.V.
    Inventor: Vernon K. Jenkins
  • Patent number: 5166179
    Abstract: N-benzoyl-N'-phenoxyphenylureas of the formula (I) ##STR1## where R.sup.1 is fluorine, chlorine or methyl, R.sup.2 is fluorine, chlorine or hydrogen, R.sup.3 and R.sup.4 are each chlorine or bromine and R.sup.5 and R.sup.6 can be identical or different and are each fluorine, chlorine, bromine, trifluoromethyl or hydrogen, processes for their preparation and their use for controlling pests.
    Type: Grant
    Filed: March 1, 1988
    Date of Patent: November 24, 1992
    Inventors: Arno Lange, Heinrich Adolphi
  • Patent number: 5135953
    Abstract: A method of systemically controlling endoparasites and ectoparasites of warm-blooded animals by orally or percutaneously administering to the animal a parasiticidally effective amount of an acyl urea compound.
    Type: Grant
    Filed: December 6, 1985
    Date of Patent: August 4, 1992
    Assignee: Ciba-Geigy
    Inventors: Michael F. Potter, George L. Rotramel, Andrew J. Caruso, David T. Chou, Paul A. Cain
  • Patent number: 5132325
    Abstract: The invention relates to novel substituted N-benzoyl-N'-2,5-dihalo-4-haloalkoxyphenylureas of formula I ##STR1## wherein each of R.sub.1 and R.sub.2 is halogen, with the proviso that R.sub.1 and R.sub.2 may not simultaneously be chlorine, R.sub.3 is a mono- or polyhalogenated C.sub.1 -C.sub.7 alkyl group, R.sub.4 is hydrogen, halogen, methyl, methoxy or methylthio and R.sub.5 is halogen, methyl, methoxy or methylthio, to processes and intermediates for the preparation thereof, to the use thereof in pest control and to compositions containing, as active ingredient, at least one compound of formula I. The preferred area of application of said novel compounds is the control of pests of animals and plants.
    Type: Grant
    Filed: February 13, 1991
    Date of Patent: July 21, 1992
    Assignee: Ciba-Geigy Corporation
    Inventor: Jozef Drabek
  • Patent number: 5125967
    Abstract: A composition comprises an isothiazolinone or an isothiazolothione and a substituted urea or a halogen-containing aromatic alkyl sulphoxide or sulphone. The isothiazolinone derivative can be 1,2-benzisothiazolin-3-one. The substituted urea may be 3-(3,4-dichlorophenyl)-1-1-dimethylurea. The sulphoxide or sulphone may be a sulphone derivative such as di-iodomethyl-4-methylphenyl sulphone. A useful composition comprises 1,2-benzisothiazolin-3-one and the specified urea or sulphone derivative. The composition may include other materials including other compounds having anti-microbial properties.
    Type: Grant
    Filed: March 29, 1990
    Date of Patent: June 30, 1992
    Assignee: Imperial Chemical Industries PLC
    Inventors: Fraser F. Morpeth, Malcolm Greenhalgh
  • Patent number: 5116875
    Abstract: A novel benzxoylurea derivative represented by the formula (I) described below, its production and an insecticidal and/or acaricidal composition containing it as an active ingredient: ##STR1## wherein R.sub.1 is a chlorine or fluorine atom, each of R.sub.2 and R.sub.3, wherein may be the same or different, is a fluorine or hydrogen atom, R.sub.4 is a chlorine or hydrogen atom, R.sub.5 is a halogen atom or a methyl or trifluoromethyl group, and X is an oxygen or sulfur atom.
    Type: Grant
    Filed: July 25, 1990
    Date of Patent: May 26, 1992
    Assignee: Sumitomo Chemical Company, Limited
    Inventors: Noriyasu Sakamoto, Tatsuya Mori, Tadashi Ohsumi, Hiroaki Fujimoto, Izumi Fujimoto
  • Patent number: 5107017
    Abstract: The invention relates to novel substituted N-benzoyl-N'-2,5-dichloro-4-hexafluoropropyloxyphenylureas of the formula ##STR1## wherein R.sub.1 is hydrogen, fluorine, chlorine or methoxy, and R.sub.2 is fluorine, chlorine or methoxy, and to the salts thereof; to processes and intermediates for the preparation of these compounds and to compositions containing the novel compounds for controlling insects and representatives of the order Acarina, in particular plant-destructive insects.
    Type: Grant
    Filed: October 15, 1990
    Date of Patent: April 21, 1992
    Assignee: Ciba-Geigy Corporation
    Inventors: Jozef Drabek, Manfred Boger
  • Patent number: 5096928
    Abstract: Insecticidal substituted benzoyl(thio) ureas of the formula ##STR1## in which Q stands for oxygen or sulphur,R.sup.1 stands for hydrogen, halogen, nitro, methyl or trifluoromethyl,R.sup.2 stands for hydrogen, fluorine or chlorine,R.sup.3 stands for hydrogen, fluorine or chlorine,R.sup.4 stands for hydrogen or fluorine,R.sup.5 stands for hydrogen or halogen andn stands for the numbers 2, 3 or 4.Intermediates of the formula ##STR2## are also new.
    Type: Grant
    Filed: September 24, 1990
    Date of Patent: March 17, 1992
    Assignee: Bayer Aktiengesellschaft
    Inventors: Wilhelm Sirrenberg, Albrecht Marhold, Benedikt Becker, Wilhelm Stendel
  • Patent number: 5089525
    Abstract: A class of particularly active insecticidal compounds: N-(halobenzoyl)-N'-2-halo-4-[1,1,2-trifluoro-2-(trifluoromethoxy)ethoxy]-p henyl-ureas, the preparation of such compounds and their use against infestations by insects.
    Type: Grant
    Filed: September 2, 1988
    Date of Patent: February 18, 1992
    Assignee: Istituto Guido Donegani S.p.A.
    Inventors: Pietro Massardo, Giovanni Meazza, Franco Bettarini, Paolo Castoro, Vincenzo Caprioli
  • Patent number: 5075337
    Abstract: Deuterated 2-alkylaminoacetamide compounds are described having the alpha carbon of the alkyl side chain of the compounds substituted by one or two deuterium atoms. These compounds have pharmacokinetic properties which enable treatment of CNS diseases with lower toxic effects. These compounds are also useful in evaluating the metabolic fate of non-deuterated counterpart compounds. Of particular interest are compounds of Formula I: ##STR1## wherein X is deutero or hydrido; wherein R.sup.1 is selected from alkyl and aralkenyl; wherein each of R.sup.2 and R.sup.3 is independently selected from hydrido and alkyl; wherein each of R.sup.1, R.sup.2 and R.sup.3 having a substitutable position may be substituted with one or more halo radicals; or a pharmaceutically-acceptable salt thereof.
    Type: Grant
    Filed: July 26, 1989
    Date of Patent: December 24, 1991
    Assignee: G. D. Searle & Co.
    Inventors: Alex A. Cordi, Philippe Janssens de Varebeke, Hugo Gorissen
  • Patent number: 4985460
    Abstract: The present invention relates to a novel benzoylurea derivative represented by the formula; ##STR1## its production; and insecticides, ovicides for insects and chemosterilants for insects containing it as an active ingredient.
    Type: Grant
    Filed: July 28, 1989
    Date of Patent: January 15, 1991
    Assignee: Sumitomo Chemical Company, Limited
    Inventors: Noriyasu Sakamoto, Tatsuya Mori, Tadashi Ohsumi, Toshihiko Yano, Izumi Fujimoto, Yoji Takada
  • Patent number: 4983605
    Abstract: A pharmaceutical composition comprising a benzoyl urea compound (A) selected from the group consisting of a benzoyl urea compound (I) having the formula: ##STR1## wherein X is a halogen atom, a nitro group or a trifluoromethyl group, provided that when Y is a nitro group, X is a halogen atom or a nitro group, Y is a hydrogen atom, a halogen atom, a nitro group or a trifluoromethyl group, Z.sub.1 is a halogen atom or a trifluoromethyl group, Z.sub.2 is a hydrogen atom or a halogen atom, and A is a .dbd.CH-- group or a nitrogen atom, and a benzoyl urea compound (II) having the formula: ##STR2## wherein each of X.sub.1 and X.sub.2 is a hydrogen atom, a halogen atom or a nitro group, provided that when Y is a nitro group, X.sub.
    Type: Grant
    Filed: October 20, 1987
    Date of Patent: January 8, 1991
    Assignees: Ishihara Sangyo Kaisha Ltd., The Green Cross Corporation
    Inventors: Nobuo Kondo, Masahiro Kikuchi, Tsunetaka Nakajima, Masahiro Watanabe, Kazumasa Yokoyama, Takahiro Haga, Nobutoshi Yamada, Hideo Sugi, Toru Koyanagi
  • Patent number: 4980376
    Abstract: Compounds are disclosed having formula: ##STR1## wherein: R is Cl, F;R.sub.1 is H, Cl, F;R.sub.2 and R.sub.5, equal to or differing from each other, are H, halogen, alkyl C.sub.1 -C.sub.4 ;R.sub.3 and R.sub.4, equal to or differing from each other, are: H, halogen, alkyl, haloalkyl, alkoxy, haloalkoxy, alkenyl, haloalkenyl, alkenyloxy, haloalkenyloxy or alkynyl;Z is O, S or a group NR.sub.7, wherein R.sub.7 is alkyl C.sub.1 -C.sub.3 or H;Y is alkylene C.sub.2 -C.sub.4, haloethylene or haloethenyl;R.sub.6 is alkyl C.sub.1 -C.sub.4, haloalkyl C.sub.1 -C.sub.4, alkenyl C.sub.3 -C.sub.4, haloalkenyl C.sub.3 -C.sub.4, cycloalkyl C.sub.3 -C.sub.4, halocycloalkyl C.sub.3 -C.sub.4 or cycloalkenyl C.sub.3 -C.sub.4.The compounds having formula (I) are endowed with an elevated insecticide activity, which shows itself chiefly against insect larvae and eggs.
    Type: Grant
    Filed: June 19, 1990
    Date of Patent: December 25, 1990
    Assignee: Istituto Guido Donegani S.p.A.
    Inventors: Pietro Massardo, Paolo Piccardi, Franco Rama, Vincenzo Caprioli
  • Patent number: 4973589
    Abstract: The present invention relates to a method of treating dogs and cats having topically disposed fleas. More particularly, the invention relates to such a method of treatment wherein the dog or cat is dosed with a larvicidally or ovicidally effective amount of flea growth inhibiting substance capable of reaching the flea via the hosts blood.
    Type: Grant
    Filed: February 13, 1989
    Date of Patent: November 27, 1990
    Assignee: Ciba-Geigy Corporation
    Inventors: Sharron H. Barnett, Roland H. Johnson, Douglas I. Hepler
  • Patent number: 4954529
    Abstract: Compounds of the general formula I ##STR1## in which A denotes a radical of the formula A.sup.1, A.sup.2 or A.sup.3 ##STR2## R.sup.1 to R.sup.3 in each case independently of one another denote hydrogen or halogen,the radicals R.sup.4 in each case independently of one another denote halogen, (C.sub.1 -C.sub.3)halogenoalkyl or nitro,R.sup.5 denotes (C.sub.1 -C.sub.5)alkyl, which can be halogenated,X denotes oxygen or sulfur,n denotes a number from 0 to 2 andm denotes a number from 1 to 4 with the proviso that (R.sup.4).sub.m does not by itself denote halogen or by itself denote nitro, and where A=A.sup.1, salts thereof which can be used in agriculture, have advantageous acaricidal and insecticidal properties.Processes for the preparation of the compounds of the formula I are furthermore described.
    Type: Grant
    Filed: December 2, 1988
    Date of Patent: September 4, 1990
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Volker Koch, Stefan Schnatterer, Werner Bonin, Manfred Kern, Werner Knauf, Anna Waltersdorfer
  • Patent number: 4935413
    Abstract: A physical property-improving reagent which comprises an alkenoylcarbamate compound of the formula: ##STR1## wherein R is a hydrogen atom or a lower alkyl group, X is an oxygen atom (--O--), a sulfur atom (--S--) or a substituted or unsubstituted imino group (--NR'--), R' being a hydrogen atom or a lower alkyl group, and Y is the residue of an active hydrogen atom-containing compound excluding --X-H therefrom dissolved in an organic solvent having a solubility parameter of not less than 8, which can impact excellent physical properties to a polymer produced with the same.
    Type: Grant
    Filed: June 5, 1987
    Date of Patent: June 19, 1990
    Assignee: Nippon Paint Co., Ltd.
    Inventors: Satoshi Urano, Ryuzo Mizuguchi, Noriyuki Tsuboniwa, Kei Aoki, Yuji Suzuki, Takeyasu Itoh
  • Patent number: 4925875
    Abstract: Novel substituted N-benzoyl-N'-2,5-dihalo-4-perfluoroalkoxyphenylureas of formula I ##STR1## in which R.sub.1 is hydrogen, fluorine, chlorine or bromine; R.sub.2 is fluorine or chlorine; each of R.sub.3 and R.sub.4 is fluorine, chlorine or bromine; and n is 2, 3, 4, 5, 6, 7 or 8, processes and intermediates for their prepraration, their use in pest control, and pesticidal compositions that contain at least one compound of formula I as active ingredient, are disclosed. The preferred field of application is the control of pests in and on animals and plants.
    Type: Grant
    Filed: July 13, 1988
    Date of Patent: May 15, 1990
    Assignee: Ciba-Geigy Corporation
    Inventors: Jozef Drabek, Urs Siegrist
  • Patent number: 4925876
    Abstract: The invention relates to novel substituted N-benzoyl-N'-2,3,5-trihalo-4-haloalkoxyphenylureas of formula I ##STR1## wherein R.sub.1 is CF.sub.3, CF.sub.2 CF.sub.3 or CF.sub.2 CF.sub.2 CF.sub.3, to the preparation of these compounds and to intermediates for their synthesis. The invention further relates to the use of the novel compounds for use in pest control and to pesticidal compositions which contain at least one compound of formula I as active component. The preferred utility is the control of pests of animals and plants.
    Type: Grant
    Filed: April 28, 1988
    Date of Patent: May 15, 1990
    Assignee: Ciba-Geigy Corporation
    Inventor: Jozef Drabek
  • Patent number: 4920135
    Abstract: Certain organic compounds derived from urea or thiourea having insecticidal activity and methods of their preparation are disclosed. The compounds according to the invention have been found to interfere with the mechanism of metamorphoses which occurs in insects. Hence, the substances according to the invention are specifically active against insects. Owing to this specificity and because of the absence of phytotoxicity effects, the compounds of this invention are of prime importance.
    Type: Grant
    Filed: February 7, 1989
    Date of Patent: April 24, 1990
    Assignee: Duphar International Research B.V.
    Inventors: Kobus Wellinga, Rudolf Wulder
  • Patent number: 4910018
    Abstract: Novel substituted N-benzoyl-N'-2,4-difluoro-3,5-dihalophenylureas of formula I ##STR1## wherein R is hydrogen or fluorine; R.sub.1 is hydrogen, fluorine, chlorine or methoxy; R.sub.2 is fluorine, chlorine or methoxy; R.sub.3 is bromine and R.sub.4 is chlorine or bromine; or R.sub.3 is chlorine and R.sub.4 is bromine, processes and intermediates for their preparation, their use in pest control, and pesticides that contain a compound of formula I as active ingredient, are disclosed. The preferred field of application is the control of pests on animals and plants.
    Type: Grant
    Filed: September 14, 1988
    Date of Patent: March 20, 1990
    Assignee: Ciba-Geigy Corp.
    Inventor: Jozef Drabek
  • Patent number: 4904696
    Abstract: The present invention relates to a novel benzoylurea derivative represented by the formula, ##STR1## its production and insecticides containing it as an active ingredient.
    Type: Grant
    Filed: February 1, 1988
    Date of Patent: February 27, 1990
    Assignee: Sumitomo Chemical Company, Limited
    Inventors: Noriyasu Sakamoto, Tatsuya Mori, Tadashi Ohsumi, Toshihiko Yano, Izumi Fujimoto, Yoji Takada