Additional C=o Bonded Directly To Urea Nitrogen Patents (Class 514/594)
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Patent number: 5981596Abstract: There is provided a method for the control of resistant populations of Lepidoptera: Olethreutidae such as Cydia pomonella (L.), Laspeyresia pomonella (L.) Grapholitha molesta (Busck), and the like and the protection of fruit crops therefrom which comprises contacting said Lepidoptera with a toxic amount of flufenoxuron.Type: GrantFiled: January 5, 1998Date of Patent: November 9, 1999Assignee: American Cyanamid CompanyInventor: Emmanuel Thienpont
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Patent number: 5973008Abstract: The present invention relates to a method for controlling domestic pests using 2-chloro-N-[{(4'-chloro-2-methoxy[1,1'-biphenyl]4-yl)amino}carbonyl]benzam ide. The benzamide is particularly effective against termites and is suitable for use in baits.Type: GrantFiled: April 18, 1997Date of Patent: October 26, 1999Assignee: FMC CorporationInventors: Alan R. DeAngelis, Jane A. Dybas, John A. Dixson
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Patent number: 5952386Abstract: The present invention provides dihalopropene compounds of the general formula: ##STR1## wherein R.sub.1 is C.sub.1 -C.sub.10 alkyl or the like; L is C(.dbd.O)NH or the like; R.sub.2, R.sub.3 and R.sub.4 are independently halogen or the like; R.sub.5, R.sub.6 and R.sub.7 are independently hydrogen or the like; m is an integer of 0 to 4; n is an integer of 0 to 2; X is chlorine or the like; Y is oxygen or the like; and Z is oxygen or the like, which have excellent insecticidal activity so that they are satisfactorily effective for the control of noxious insects.Type: GrantFiled: September 24, 1997Date of Patent: September 14, 1999Assignee: Sumitomo Chemical Company, LimitedInventors: Sanshiro Matsuo, Taro Hirose, Keiichi Izumi, Masaya Suzuki, Noriyasu Sakamoto, Kazunori Tsushima, Shigeru Saito, Hirotaka Takano
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Patent number: 5945453Abstract: Compounds of the formula (I) ##STR1## wherein R.sup.1 and R.sup.2 are H, methyl, or ethyl, and wherein at least one of R.sup.1 and R.sup.2 is methyl or ethyl, are disclosed to control cockroaches.Type: GrantFiled: October 31, 1997Date of Patent: August 31, 1999Assignee: Dow AgroSciences LLCInventors: Ronald J. Sbragia, George W. Johnson, Laura L. Karr, Jeff M. Edwards, Brian M. Schneider
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Patent number: 5910323Abstract: This invention provides a novel aqueous pesticide formulation having a fungicidal bicarbonate-containing inorganic salt ingredient which enhances the efficacy of an insecticidal ingredient for treatment of cultivated crops. An invention pesticide formulation also contains a water-soluble organic compound which functions as a compatibility enhancing ingredient in the aqueous pesticide formulation, and improves the spreadability and adhesiveness of the composition ingredients when applied to foliage.Type: GrantFiled: October 21, 1993Date of Patent: June 8, 1999Assignee: Church & Dwight Co., Inc.Inventors: M. Stephen Lajoie, Amy L. Joseph, Keith A. Jones, Anthony E. Winston
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Patent number: 5886221Abstract: Compounds of the formula (I) ##STR1## wherein R.sup.1 and R.sup.2 are H, methyl, or ethyl, have unexpected activity against cockroaches, ants, fleas, and termites. Compounds wherein at least one of R.sup.1 and R.sup.2 is methyl or ethyl are novel.Type: GrantFiled: November 3, 1997Date of Patent: March 23, 1999Assignee: Dow AgroSciences LLCInventors: Ronald J. Sbragia, George W. Johnson, Laura L. Karr, Jeff M. Edwards, Brian M. Schneider
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Patent number: 5854288Abstract: The use of compounds of the formula I ##STR1## in which R.sup.1 -R.sup.6, A, B und X have the meaning given in detail in the description, for controlling house dust mites.The miticide has a high miticidal effect against house dust mites of Tyrophagus, Dermatophagoides, Cheyletidae, etc. and is harmless to humans and beasts. It is effective not only in exterminating such house dust mites but also in preventing from them.Type: GrantFiled: August 2, 1996Date of Patent: December 29, 1998Assignee: Hoechst Schering AgrEvo GmbHInventors: Yoshio Katsuda, Hans-Herbert Schubert, Hilmar Mildenberger, Stefan Schnatterer, Herbert Stark
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Patent number: 5837734Abstract: This invention relates to the use of acyl urea compounds for the treatment or prophylaxis of Coccidioides immitis infections in warm-blooded animals. The invention has particular application in the treatment, prophylaxis or reduction of coccidioidomycosis.Type: GrantFiled: May 1, 1996Date of Patent: November 17, 1998Assignee: Novartis CorporationInventors: Robert C. Bartsch, Russell T. Greene
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Patent number: 5811461Abstract: Compounds of formula (I): ##STR1## wherein R.sup.1 is --CF=CFCF.sub.3 or --CF.sub.2 CF=CFCF.sub.3 are useful in control of cockroaches, ants, fleas, or termites.Type: GrantFiled: October 31, 1997Date of Patent: September 22, 1998Assignee: Dow AgroSciences LLCInventors: Ronald E. Hackler, George W. Johnson, John M. Owen
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Patent number: 5776981Abstract: A method of systemically controlling endoparasites and ectoparasites of warm-blooded animals by orally or percutaneously administering to the animal a parasiticidally effective amount of an acyl urea compound.Type: GrantFiled: April 21, 1995Date of Patent: July 7, 1998Assignee: Novartis CorporationInventors: Michael Fred Potter, George Lorton Rotramel, Andrew James Caruso, David Teh-Wei Chou, Paul Alfred Cain
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Patent number: 5776982Abstract: A method of systemically controlling endoparasites and ectoparasites of warm-blooded animals by orally or percutaneously administering to the animal a parasiticidally effective amount of an acyl urea compound.Type: GrantFiled: May 31, 1995Date of Patent: July 7, 1998Assignee: Novartis CorporationInventors: Michael Fred Potter, George Lorton Rotramel, Andrew James Caruso, David Teh-Wei Chou, Paul Alfred Cain
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Patent number: 5728719Abstract: The present invention is a method for controlling ectoparasites. More particularly, the invention relates to a method of treatment in which the warm blooded animal is dosed with an ovicidally effective amount of a heterocyclic nitrogen compound selected from the group represented by the formula: ##STR1## wherein R.sub.1, is either one of the following groups: ##STR2## in which R.sub.7, R.sub.8, R.sub.9, R.sub.10, R.sub.11, R.sub.12, R.sub.13, R.sub.14, R.sub.15, R.sub.16, and R.sub.17 are, the same or different, each a hydrogen atom, a halogen atom, a C.sub.1 -C.sub.4 alkoxy group, a C.sub.1 -C.sub.4 alkylthio group, a trifluoro methyl group or a vitro group, R.sub.18, R.sub.19, R.sub.20 and R.sub.21 are, the same or different, each a hydrogen atom or a methyl group, k is an integer of 0 to 1 and 1 is an integer of 0 to 3; R.sub.2 and R.sub.3 are, the same or different, each a hydrogen atom, a halogen atom or a methyl group; R.sub.4 is a halogen atom or a methyl group; R.sub.5 and R.sub.Type: GrantFiled: March 14, 1995Date of Patent: March 17, 1998Assignee: Virbac, Inc.Inventor: Thomas A. Miller
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Patent number: 5691383Abstract: Method of using specific acyl urea compounds as termiticides. The compounds are unusually non-repellant to termites and active at low dosages.Type: GrantFiled: June 26, 1996Date of Patent: November 25, 1997Assignee: DowElancoInventors: Ellen M. Thoms, Ronald J. Sbragia
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Patent number: 5637298Abstract: 2-naphthalenemethanol [Chemical Abstracts registry no. 1592-38-7] produces a high degree of trail-following activity in termites. The attractant 2-naphthalenemethanol and certain derivatives increase bait acceptance by termites, improving the ability of termite baits to kill colonies, allowing lower amounts of toxicant to be used, or both.Type: GrantFiled: June 14, 1996Date of Patent: June 10, 1997Assignee: Board of Supervisors of Louisiana State University and Agricultural and Mechanical CollegeInventor: John C. Stowell
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Patent number: 5607977Abstract: Compounds of the formula ##STR1## wherein R.sub.1 is fluorine, chlorine, bromine or iodine; and A is 2,6-difluorophenyl, 2-chlorophenyl, 2-chloro-6-fluorophenyl, 2,6-dichlorophenyl or 2-fluorophenyl,with the proviso that when R.sub.1 is chlorine, A is other than 2,6-dichlorophenyl, useful as pesticides.Type: GrantFiled: October 22, 1991Date of Patent: March 4, 1997Assignee: Shell Agrar GmbH & Co. KGInventors: Heinz-Manfred Becher, Christo Drandarevski, Rudolf Mengel, Walter Ost
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Patent number: 5583089Abstract: This invention provides a dry blend pesticide composition which contains a fungicidal bicarbonate salt ingredient, and a spreader-sticker ingredient which is a crystalline clathrate complex of a urea constituent and a normally liquid spreader sticker constituent such as a nonionic surfactant. In a preferred embodiment all of the composition ingredients are water-soluble, and the composition is readily dispersible in an aqueous medium to form a sprayable pesticide solution.Type: GrantFiled: May 9, 1995Date of Patent: December 10, 1996Assignee: Church & Dwight Co., Inc.Inventor: Anthony E. Winston
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Patent number: 5556883Abstract: Method of using specific acyl urea compounds as termiticides. The compounds are unusually non-repellant to termites and active at low dosages.Type: GrantFiled: May 11, 1995Date of Patent: September 17, 1996Assignee: DowElancoInventors: Ellen M. Thoms, Ronald J. Sbragia
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Patent number: 5527823Abstract: A formulation suitable for spraying or for dilution with water to form a sprayable preparation, the formulation comprising an active ingredient, optionally a carrier or solvent for the active ingredient, an emulsifier and an evaporation retardant, characterized in that the formulation satisfies formula ##EQU1## where L is less than or equal to 15, A=700376, B=-1.51, C=0.8472, M.sub.oil is the weighted average relative molar mass of the oil phase M.sub.retardant is the weighted average relative molar mass of the retardant, and X=(M.sub.oil) 1.8/Y, where Y is the molar solubility ration of the formulation, defined as the minimum number of moles of the oil phase which will dissolve the retardant, divided by the number of moles of retardant, provided that, in the formula above, any solvent which has no liquid phase at 27.degree. C. at atmospheric pressure is excluded. The formulation may comprise a pesticide or herbicide. The action of the evaporation retardant is improved.Type: GrantFiled: February 8, 1994Date of Patent: June 18, 1996Assignee: Roussel UCLAFInventors: Robert Martin, David A. Jeffries, Denise K. North, John M. Groome, Peter L. Crampton, Andrew J. Huson
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Patent number: 5432148Abstract: This invention provides a fungicide composition which is capable of in situ generation of ammonium bicarbonate when applied to plant foliage in the form of an aqueous dispersion. The constituents include (1) an ingredient such as urea which slow-releases ammonia under aqueous alkaline pH conditions; and (2) an alkali metal bicarbonate ingredient which imparts alkalinity to the aqueous dispersion, and provides bicarbonate ions for combination with the released ammonium ions. A spreader-sticker ingredient is included to maintain the ingredients in contact with plant foliage over an extended period after application.Type: GrantFiled: December 7, 1994Date of Patent: July 11, 1995Assignee: Church & Dwight Co., Inc.Inventor: Anthony E. Winston
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Patent number: 5425952Abstract: This invention provides a fungicide composition which is capable of in situ generation of ammonium bicarbonate when applied to plant foliage in the form of an aqueous dispersion. The constituents include (1) an ingredient such as urea which slow-releases ammonia under aqueous alkaline pH conditions; and (2) an alkali metal bicarbonate ingredient which imparts alkalinity to the aqueous dispersion, and provides bicarbonate ions for combination with the released ammonium ions. A spreader-sticker ingredient is included to maintain the ingredients in contact with plant foliage over an extended period after application.Type: GrantFiled: October 13, 1993Date of Patent: June 20, 1995Assignee: Church & Dwight Co., Inc.Inventor: Anthony E. Winston
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Patent number: 5423905Abstract: The invention relates to a formulation for protecting keratinous material from attack by pests that feed on keratin, comprising (A) at least one diphenylurea of formula ##STR1## wherein R.sub.1 is hydrogen or 4-chlorophenoxy-6-sulfonate,R.sub.2 is hydrogen or chloro,R.sub.3 is chloro or trifluoromethyl,R.sub.4 is hydrogen or chloro, andR.sub.5 is hydrogen or trifluoromethyl, and(B) at least one glycol, and to a process for protecting keratinous material against attack by pests that feed on keratin with the novel formulation.Type: GrantFiled: July 18, 1994Date of Patent: June 13, 1995Assignee: Ciba-Geigy CorporationInventor: Werner Fringeli
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Patent number: 5420163Abstract: A method of systemically controlling endoparasites and ectoparasites of warm-blooded animals by orally or percutaneously administering to the animal a parasiticidally effective amount of an acyl urea compound.Type: GrantFiled: August 3, 1992Date of Patent: May 30, 1995Assignee: Ciba-GeigyInventors: Michael F. Potter, George L. Rotramel, Andrew J. Caruso, David T. Chou, Paul A. Cain
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Patent number: 5416102Abstract: A method of treating fleas on dogs and cats by orally administering a larvicidally or ovicidally effective amount of flea growth inhibiting benzoylurea.Type: GrantFiled: June 27, 1994Date of Patent: May 16, 1995Assignee: Ciba-Geigy CorporationInventors: Sharron H. Barnett, Roland H. Johnson, Douglas I. Hepler, Manfred Boger
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Patent number: 5288756Abstract: The invention relates to novel substituted N-benzoyl-N'-3,5-dichlorohexafluoropropyloxyphenylureas of the formula ##STR1## wherein R.sub.1 is hydrogen or fluorine and R.sub.2 is fluorine or chlorine, and to salts thereof; to processes and intermediates for the preparation of these compounds and to compositions containing the novel compounds for controlling insects, representatives of the order Acarina and slugs and snails, in particular plant-destructive insects.Type: GrantFiled: August 5, 1992Date of Patent: February 22, 1994Assignee: Ciba-Geigy CorporationInventor: Jozef Drabek
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Patent number: 5288758Abstract: New urea derivatives corresponding to the general formula 1 ##STR1## in which: R.sup.1 represents a C.sub.1 -C.sub.4 alkyl group;R.sup.2 represents:a C.sub.5 -C.sub.7 cycloalkyl groupa cycloalkylmethyl group in which the cycloalkyl radical contains from 5 to 7 carbon atomsa benzyl groupa benzyl group in which the aromatic ring bears a C.sub.1 -C.sub.4 alkyl group, a C.sub.1 -C.sub.4 alkoxy group, a halogen atom or a nitro group;A represents an oxygen atom or a methylene radical;n represents 1 or 2;X represents an oxygen or sulfur atom;B represents a direct bond, a methylene radical or a carbonyl radical;as well as the therapeutically acceptable salts of these molecules.The invention also relates to the application of the compounds of general formula 1 in therapy, and to the preparation processes.Type: GrantFiled: July 22, 1992Date of Patent: February 22, 1994Assignee: Pierre Fabre MedicamentInventors: Jean-Louis Vidaluc, Dennis Bigg
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Patent number: 5264213Abstract: A highly active water-dispersible pesticide formulation is prepared by dissolving at least a part of a benzoyl phenyl urea series insecticidal compound in an organic solvent, contacting the so obtained mixture with a carrier material, and pulverizing the resulting mixture. The pesticidal formulation obtained has higher pesticidal activity than formulations prepared by a conventional dry methods.Type: GrantFiled: July 7, 1989Date of Patent: November 23, 1993Assignee: DowElancoInventors: Tetsuya Shibahara, Naohiko Kondo, Jun Kato
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Patent number: 5210100Abstract: The invention relates to novel N-[3-halo-4-(hexafluoropropoxy)-5-trifluoromethyl]phenyl-N'-benzoylureas of the formula ##STR1## wherein R.sub.1 is hydrogen or halogen and R.sub.2 and R.sub.3 are halogen, to a process and intermediate for the preparation of these compounds, and to compositions containing them for use in pest control, in particular for controlling insects and representatives of the order Acarina that attack plants and animals. The novel compounds exhibit in particular larvicidal activity.Type: GrantFiled: October 25, 1989Date of Patent: May 11, 1993Assignee: Ciba-Geigy CorporationInventor: Josef Ehrenfreund
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Patent number: 5177110Abstract: Parenterally injectable compositions for controlling parasites, which compositions contain from 0.1 to 10% of a benzoylurea as active ingredient, from 0.1 to 60% of a 1-substituted azacycloalkan-2-one, from 2 to 90% of a physiologically tolerable surfactant or mixture of surfactants and, if appropriate, as stabilizing component, from 0.05 to 15% of an acid or a buffer mixture and add 100% of a physiologically tolerable hydrophilic solvent or mixture of solvents or a mixture of physiologically tolerable hydrophilic and lipophilic solvents.Type: GrantFiled: April 22, 1991Date of Patent: January 5, 1993Assignee: Ciba-Geigy CorporationInventors: Walter Oechslein, Jean-Claude Gehret, Ernst Hess, Sabine Rossow
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Patent number: 5169846Abstract: A non-aqueous micellar solution, for use in animal health, of one or more non water-soluble Anthelmintics and or insect growth regulators in a polyethoxylated oil or fat surfactant and one or more co-solvents chosen from a group comprising dimethyl sulphoxide (DMSO), N-methyl pyrollidone (NMP), tetraglycol (TG) and propylene glycol (PG).Type: GrantFiled: October 11, 1990Date of Patent: December 8, 1992Inventor: Michael J. Crooks
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Patent number: 5166180Abstract: The present invention relates to a method of treating hematopoietic diseases in warm-blooded living beings. The method is carried out by administering an effective amount of a compound of the formula ##STR1## wherein R.sub.5 represents (a) 1-3 substituents selected from the group consisting of halogen, C.sub.1 -C.sub.6 alkyl, trifluoromethyl, C.sub.1 -C.sub.4 alkoxy, C.sub.1 -C.sub.4 alkylthio, hydroxy, C.sub.2 -C.sub.5 alkanoyloxy, amino, N, N-di(C.sub.1 -C.sub.4) alkylamino and piperidyl; or (b) five fluorine atoms;R.sub.6 represents 1-3 substituents selected from the group consisting of halogen, C.sub.1 -C.sub.4 alkyl, trifluoromethyl, C.sub.1 -C.sub.4 alkoxy, C.sub.1 -C.sub.4 haloalkoxy, cyclohexyloxy, adamantyloxy, hydroxy, amino and N-C.sub.2 -C.sub.5 alkanoylamino;X is oxygen or sulphur, andY is oxygen or sulphur.Type: GrantFiled: February 27, 1990Date of Patent: November 24, 1992Assignee: Duphar International Research B.V.Inventor: Vernon K. Jenkins
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Patent number: 5166179Abstract: N-benzoyl-N'-phenoxyphenylureas of the formula (I) ##STR1## where R.sup.1 is fluorine, chlorine or methyl, R.sup.2 is fluorine, chlorine or hydrogen, R.sup.3 and R.sup.4 are each chlorine or bromine and R.sup.5 and R.sup.6 can be identical or different and are each fluorine, chlorine, bromine, trifluoromethyl or hydrogen, processes for their preparation and their use for controlling pests.Type: GrantFiled: March 1, 1988Date of Patent: November 24, 1992Inventors: Arno Lange, Heinrich Adolphi
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Patent number: 5135953Abstract: A method of systemically controlling endoparasites and ectoparasites of warm-blooded animals by orally or percutaneously administering to the animal a parasiticidally effective amount of an acyl urea compound.Type: GrantFiled: December 6, 1985Date of Patent: August 4, 1992Assignee: Ciba-GeigyInventors: Michael F. Potter, George L. Rotramel, Andrew J. Caruso, David T. Chou, Paul A. Cain
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Patent number: 5132325Abstract: The invention relates to novel substituted N-benzoyl-N'-2,5-dihalo-4-haloalkoxyphenylureas of formula I ##STR1## wherein each of R.sub.1 and R.sub.2 is halogen, with the proviso that R.sub.1 and R.sub.2 may not simultaneously be chlorine, R.sub.3 is a mono- or polyhalogenated C.sub.1 -C.sub.7 alkyl group, R.sub.4 is hydrogen, halogen, methyl, methoxy or methylthio and R.sub.5 is halogen, methyl, methoxy or methylthio, to processes and intermediates for the preparation thereof, to the use thereof in pest control and to compositions containing, as active ingredient, at least one compound of formula I. The preferred area of application of said novel compounds is the control of pests of animals and plants.Type: GrantFiled: February 13, 1991Date of Patent: July 21, 1992Assignee: Ciba-Geigy CorporationInventor: Jozef Drabek
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Patent number: 5125967Abstract: A composition comprises an isothiazolinone or an isothiazolothione and a substituted urea or a halogen-containing aromatic alkyl sulphoxide or sulphone. The isothiazolinone derivative can be 1,2-benzisothiazolin-3-one. The substituted urea may be 3-(3,4-dichlorophenyl)-1-1-dimethylurea. The sulphoxide or sulphone may be a sulphone derivative such as di-iodomethyl-4-methylphenyl sulphone. A useful composition comprises 1,2-benzisothiazolin-3-one and the specified urea or sulphone derivative. The composition may include other materials including other compounds having anti-microbial properties.Type: GrantFiled: March 29, 1990Date of Patent: June 30, 1992Assignee: Imperial Chemical Industries PLCInventors: Fraser F. Morpeth, Malcolm Greenhalgh
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Patent number: 5116875Abstract: A novel benzxoylurea derivative represented by the formula (I) described below, its production and an insecticidal and/or acaricidal composition containing it as an active ingredient: ##STR1## wherein R.sub.1 is a chlorine or fluorine atom, each of R.sub.2 and R.sub.3, wherein may be the same or different, is a fluorine or hydrogen atom, R.sub.4 is a chlorine or hydrogen atom, R.sub.5 is a halogen atom or a methyl or trifluoromethyl group, and X is an oxygen or sulfur atom.Type: GrantFiled: July 25, 1990Date of Patent: May 26, 1992Assignee: Sumitomo Chemical Company, LimitedInventors: Noriyasu Sakamoto, Tatsuya Mori, Tadashi Ohsumi, Hiroaki Fujimoto, Izumi Fujimoto
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Patent number: 5107017Abstract: The invention relates to novel substituted N-benzoyl-N'-2,5-dichloro-4-hexafluoropropyloxyphenylureas of the formula ##STR1## wherein R.sub.1 is hydrogen, fluorine, chlorine or methoxy, and R.sub.2 is fluorine, chlorine or methoxy, and to the salts thereof; to processes and intermediates for the preparation of these compounds and to compositions containing the novel compounds for controlling insects and representatives of the order Acarina, in particular plant-destructive insects.Type: GrantFiled: October 15, 1990Date of Patent: April 21, 1992Assignee: Ciba-Geigy CorporationInventors: Jozef Drabek, Manfred Boger
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Patent number: 5096928Abstract: Insecticidal substituted benzoyl(thio) ureas of the formula ##STR1## in which Q stands for oxygen or sulphur,R.sup.1 stands for hydrogen, halogen, nitro, methyl or trifluoromethyl,R.sup.2 stands for hydrogen, fluorine or chlorine,R.sup.3 stands for hydrogen, fluorine or chlorine,R.sup.4 stands for hydrogen or fluorine,R.sup.5 stands for hydrogen or halogen andn stands for the numbers 2, 3 or 4.Intermediates of the formula ##STR2## are also new.Type: GrantFiled: September 24, 1990Date of Patent: March 17, 1992Assignee: Bayer AktiengesellschaftInventors: Wilhelm Sirrenberg, Albrecht Marhold, Benedikt Becker, Wilhelm Stendel
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Patent number: 5089525Abstract: A class of particularly active insecticidal compounds: N-(halobenzoyl)-N'-2-halo-4-[1,1,2-trifluoro-2-(trifluoromethoxy)ethoxy]-p henyl-ureas, the preparation of such compounds and their use against infestations by insects.Type: GrantFiled: September 2, 1988Date of Patent: February 18, 1992Assignee: Istituto Guido Donegani S.p.A.Inventors: Pietro Massardo, Giovanni Meazza, Franco Bettarini, Paolo Castoro, Vincenzo Caprioli
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Patent number: 5075337Abstract: Deuterated 2-alkylaminoacetamide compounds are described having the alpha carbon of the alkyl side chain of the compounds substituted by one or two deuterium atoms. These compounds have pharmacokinetic properties which enable treatment of CNS diseases with lower toxic effects. These compounds are also useful in evaluating the metabolic fate of non-deuterated counterpart compounds. Of particular interest are compounds of Formula I: ##STR1## wherein X is deutero or hydrido; wherein R.sup.1 is selected from alkyl and aralkenyl; wherein each of R.sup.2 and R.sup.3 is independently selected from hydrido and alkyl; wherein each of R.sup.1, R.sup.2 and R.sup.3 having a substitutable position may be substituted with one or more halo radicals; or a pharmaceutically-acceptable salt thereof.Type: GrantFiled: July 26, 1989Date of Patent: December 24, 1991Assignee: G. D. Searle & Co.Inventors: Alex A. Cordi, Philippe Janssens de Varebeke, Hugo Gorissen
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Patent number: 4985460Abstract: The present invention relates to a novel benzoylurea derivative represented by the formula; ##STR1## its production; and insecticides, ovicides for insects and chemosterilants for insects containing it as an active ingredient.Type: GrantFiled: July 28, 1989Date of Patent: January 15, 1991Assignee: Sumitomo Chemical Company, LimitedInventors: Noriyasu Sakamoto, Tatsuya Mori, Tadashi Ohsumi, Toshihiko Yano, Izumi Fujimoto, Yoji Takada
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Patent number: 4983605Abstract: A pharmaceutical composition comprising a benzoyl urea compound (A) selected from the group consisting of a benzoyl urea compound (I) having the formula: ##STR1## wherein X is a halogen atom, a nitro group or a trifluoromethyl group, provided that when Y is a nitro group, X is a halogen atom or a nitro group, Y is a hydrogen atom, a halogen atom, a nitro group or a trifluoromethyl group, Z.sub.1 is a halogen atom or a trifluoromethyl group, Z.sub.2 is a hydrogen atom or a halogen atom, and A is a .dbd.CH-- group or a nitrogen atom, and a benzoyl urea compound (II) having the formula: ##STR2## wherein each of X.sub.1 and X.sub.2 is a hydrogen atom, a halogen atom or a nitro group, provided that when Y is a nitro group, X.sub.Type: GrantFiled: October 20, 1987Date of Patent: January 8, 1991Assignees: Ishihara Sangyo Kaisha Ltd., The Green Cross CorporationInventors: Nobuo Kondo, Masahiro Kikuchi, Tsunetaka Nakajima, Masahiro Watanabe, Kazumasa Yokoyama, Takahiro Haga, Nobutoshi Yamada, Hideo Sugi, Toru Koyanagi
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Patent number: 4980376Abstract: Compounds are disclosed having formula: ##STR1## wherein: R is Cl, F;R.sub.1 is H, Cl, F;R.sub.2 and R.sub.5, equal to or differing from each other, are H, halogen, alkyl C.sub.1 -C.sub.4 ;R.sub.3 and R.sub.4, equal to or differing from each other, are: H, halogen, alkyl, haloalkyl, alkoxy, haloalkoxy, alkenyl, haloalkenyl, alkenyloxy, haloalkenyloxy or alkynyl;Z is O, S or a group NR.sub.7, wherein R.sub.7 is alkyl C.sub.1 -C.sub.3 or H;Y is alkylene C.sub.2 -C.sub.4, haloethylene or haloethenyl;R.sub.6 is alkyl C.sub.1 -C.sub.4, haloalkyl C.sub.1 -C.sub.4, alkenyl C.sub.3 -C.sub.4, haloalkenyl C.sub.3 -C.sub.4, cycloalkyl C.sub.3 -C.sub.4, halocycloalkyl C.sub.3 -C.sub.4 or cycloalkenyl C.sub.3 -C.sub.4.The compounds having formula (I) are endowed with an elevated insecticide activity, which shows itself chiefly against insect larvae and eggs.Type: GrantFiled: June 19, 1990Date of Patent: December 25, 1990Assignee: Istituto Guido Donegani S.p.A.Inventors: Pietro Massardo, Paolo Piccardi, Franco Rama, Vincenzo Caprioli
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Patent number: 4973589Abstract: The present invention relates to a method of treating dogs and cats having topically disposed fleas. More particularly, the invention relates to such a method of treatment wherein the dog or cat is dosed with a larvicidally or ovicidally effective amount of flea growth inhibiting substance capable of reaching the flea via the hosts blood.Type: GrantFiled: February 13, 1989Date of Patent: November 27, 1990Assignee: Ciba-Geigy CorporationInventors: Sharron H. Barnett, Roland H. Johnson, Douglas I. Hepler
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Patent number: 4954529Abstract: Compounds of the general formula I ##STR1## in which A denotes a radical of the formula A.sup.1, A.sup.2 or A.sup.3 ##STR2## R.sup.1 to R.sup.3 in each case independently of one another denote hydrogen or halogen,the radicals R.sup.4 in each case independently of one another denote halogen, (C.sub.1 -C.sub.3)halogenoalkyl or nitro,R.sup.5 denotes (C.sub.1 -C.sub.5)alkyl, which can be halogenated,X denotes oxygen or sulfur,n denotes a number from 0 to 2 andm denotes a number from 1 to 4 with the proviso that (R.sup.4).sub.m does not by itself denote halogen or by itself denote nitro, and where A=A.sup.1, salts thereof which can be used in agriculture, have advantageous acaricidal and insecticidal properties.Processes for the preparation of the compounds of the formula I are furthermore described.Type: GrantFiled: December 2, 1988Date of Patent: September 4, 1990Assignee: Hoechst AktiengesellschaftInventors: Volker Koch, Stefan Schnatterer, Werner Bonin, Manfred Kern, Werner Knauf, Anna Waltersdorfer
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Patent number: 4935413Abstract: A physical property-improving reagent which comprises an alkenoylcarbamate compound of the formula: ##STR1## wherein R is a hydrogen atom or a lower alkyl group, X is an oxygen atom (--O--), a sulfur atom (--S--) or a substituted or unsubstituted imino group (--NR'--), R' being a hydrogen atom or a lower alkyl group, and Y is the residue of an active hydrogen atom-containing compound excluding --X-H therefrom dissolved in an organic solvent having a solubility parameter of not less than 8, which can impact excellent physical properties to a polymer produced with the same.Type: GrantFiled: June 5, 1987Date of Patent: June 19, 1990Assignee: Nippon Paint Co., Ltd.Inventors: Satoshi Urano, Ryuzo Mizuguchi, Noriyuki Tsuboniwa, Kei Aoki, Yuji Suzuki, Takeyasu Itoh
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Patent number: 4925875Abstract: Novel substituted N-benzoyl-N'-2,5-dihalo-4-perfluoroalkoxyphenylureas of formula I ##STR1## in which R.sub.1 is hydrogen, fluorine, chlorine or bromine; R.sub.2 is fluorine or chlorine; each of R.sub.3 and R.sub.4 is fluorine, chlorine or bromine; and n is 2, 3, 4, 5, 6, 7 or 8, processes and intermediates for their prepraration, their use in pest control, and pesticidal compositions that contain at least one compound of formula I as active ingredient, are disclosed. The preferred field of application is the control of pests in and on animals and plants.Type: GrantFiled: July 13, 1988Date of Patent: May 15, 1990Assignee: Ciba-Geigy CorporationInventors: Jozef Drabek, Urs Siegrist
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Patent number: 4925876Abstract: The invention relates to novel substituted N-benzoyl-N'-2,3,5-trihalo-4-haloalkoxyphenylureas of formula I ##STR1## wherein R.sub.1 is CF.sub.3, CF.sub.2 CF.sub.3 or CF.sub.2 CF.sub.2 CF.sub.3, to the preparation of these compounds and to intermediates for their synthesis. The invention further relates to the use of the novel compounds for use in pest control and to pesticidal compositions which contain at least one compound of formula I as active component. The preferred utility is the control of pests of animals and plants.Type: GrantFiled: April 28, 1988Date of Patent: May 15, 1990Assignee: Ciba-Geigy CorporationInventor: Jozef Drabek
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Patent number: 4920135Abstract: Certain organic compounds derived from urea or thiourea having insecticidal activity and methods of their preparation are disclosed. The compounds according to the invention have been found to interfere with the mechanism of metamorphoses which occurs in insects. Hence, the substances according to the invention are specifically active against insects. Owing to this specificity and because of the absence of phytotoxicity effects, the compounds of this invention are of prime importance.Type: GrantFiled: February 7, 1989Date of Patent: April 24, 1990Assignee: Duphar International Research B.V.Inventors: Kobus Wellinga, Rudolf Wulder
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Patent number: 4910018Abstract: Novel substituted N-benzoyl-N'-2,4-difluoro-3,5-dihalophenylureas of formula I ##STR1## wherein R is hydrogen or fluorine; R.sub.1 is hydrogen, fluorine, chlorine or methoxy; R.sub.2 is fluorine, chlorine or methoxy; R.sub.3 is bromine and R.sub.4 is chlorine or bromine; or R.sub.3 is chlorine and R.sub.4 is bromine, processes and intermediates for their preparation, their use in pest control, and pesticides that contain a compound of formula I as active ingredient, are disclosed. The preferred field of application is the control of pests on animals and plants.Type: GrantFiled: September 14, 1988Date of Patent: March 20, 1990Assignee: Ciba-Geigy Corp.Inventor: Jozef Drabek
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Patent number: 4904696Abstract: The present invention relates to a novel benzoylurea derivative represented by the formula, ##STR1## its production and insecticides containing it as an active ingredient.Type: GrantFiled: February 1, 1988Date of Patent: February 27, 1990Assignee: Sumitomo Chemical Company, LimitedInventors: Noriyasu Sakamoto, Tatsuya Mori, Tadashi Ohsumi, Toshihiko Yano, Izumi Fujimoto, Yoji Takada