Halogen Bonded Directly To Carbon In R Patents (Class 514/628)
  • Patent number: 4943307
    Abstract: The invention relates to a plant-protective solution containing 2.5 to 40 % by weight of one or more water-insoluble plant-protective ingredient(s) 20 to 71.5 % by weight of dimethylformamide and/or dimethylsulfoxide and/or acetone as water-miscible solvent, 10 to 71.5 % by weight of furfurol and/or furfuryl alcohol as partially water-miscible solvent, 1 to 15 % by weight of commonly used additives such as anionic and/or nonionic surface active agents and macromolecules.The invention also relates to the ready-for-use plant-protective suspension containing 0.2 to 10 % by weight of one or more water-insoluble plant-protective ingredient(s) with a particle size of 0.1 to 50 .mu.m, 0 to 60 % by weight of a fertilizer, 0.2 to 10 % by weight of dimethylformamide and/or dimethylsulfoxide and/or acetone as water-miscible solvent, 0.2 to 10 % by weight of furfurol and/or furfuryl alcohol as partially water-miscible solvent, 0.05 to 2.
    Type: Grant
    Filed: July 15, 1988
    Date of Patent: July 24, 1990
    Assignee: Chinoin Gyogyszer es Vegyeszeti Termekek Gyara Rt.
    Inventors: Tamas Detre, Sandor ngyan, Laszlo Pap, Andras Szego, Zoltan Karadi, Klara Bertus nee Bende, Katalin Marmarosi nee Kellner
  • Patent number: 4923506
    Abstract: A controlled release composition of biologically active materials is prepared by reacting a biologically active agent, aqueous polyhydroxy polymer, inorganic salt, and optional filler(s), drying the product and then grinding the product to the desire particle size. The product is then used, for example, for controlling pests.
    Type: Grant
    Filed: June 28, 1988
    Date of Patent: May 8, 1990
    Assignee: Pennwalt Corporation
    Inventors: Ludwig K. Huber, Harold G. Monsimer
  • Patent number: 4912138
    Abstract: Pharmaceutical preparations for veterinary use, in the form of concentrate solutions, containing Thiamphenicol as active ingredient are described.
    Type: Grant
    Filed: September 14, 1987
    Date of Patent: March 27, 1990
    Assignee: Zambon S.p.A.
    Inventors: Franco Pozzi, Claudia Tortora, Angelo Carenzi
  • Patent number: 4902715
    Abstract: Compounds of the formula ##STR1## wherein X is a halogen atom, R the same or different substituents in any desired position of the benzene ring, namely, halogen atoms, C.sub.1 -C.sub.3 -alkyl groups, trifluoromethyl groups or cyano groups and n a whole number with a value of 1, 2 or 3, are fungicidally active.
    Type: Grant
    Filed: June 27, 1988
    Date of Patent: February 20, 1990
    Assignee: The Dow Chemical Company
    Inventors: Bernd Schilling, Anneliese Reutter, Norman Haberle
  • Patent number: 4891356
    Abstract: A method of treating gastrointgestinal ulcer disease is provided which involves administration of a proteinase inhibitor or analogue to patients suffering from same. Of particular interest is the use of inhibitors of serine, cysteine, carboxyl, and metallo proteinases.
    Type: Grant
    Filed: July 15, 1987
    Date of Patent: January 2, 1990
    Assignee: Brigham & Women's Hospital
    Inventor: Sandor Szabo
  • Patent number: 4879274
    Abstract: Novel external medications comprise, as essential components, the following three components (A) to (C):(A) an .alpha.-monoglyceryl ether represented by the following formula (I): ##STR1## wherein R means an alkyl or alkenyl group having 10 - 24 carbon atoms; (B) a physiologically active material; and(C) an oily material.The external medications have extremely high skin occlusive properties and significantly-improved absorptivity of phosiologically active materials. Therefore, a smaller amount of the medications compared with the conventional ones can give sufficient pharmacological effects and thus side effects can be reduced. The external medications may contain physiologically active materials such as drugs, growth hormones and the like, which are expected to show pharmacological effects upon their percutaneous absorption.
    Type: Grant
    Filed: September 12, 1986
    Date of Patent: November 7, 1989
    Assignee: Kao Corporation
    Inventors: Tetsuro Kamiya, Shuichi Tsuchiya, Kenji Hara
  • Patent number: 4847084
    Abstract: These 2 formulae provide a new and unique method of healing decubiti ulcers. Formula #1 contains Fibrinolysin and Desoxyribonuclease, Combined-Bovine-with Chloramphenicol Ointment, Chlorophyll Ointment 0.5%, and Povidone-Iodine Ointment 10% in equal parts of each. Formula #2 contains Fibrinolysin and Desoxyribonuclease, Combined-Bovine-Ointment, Chlorophyll Ointment 0.5%, and Povidone-Iodine Ointment 10% in equal parts of each. This new unique method of healing decubiti ulcers depends on a combination of actions which include enzymatic debriding properties, infection control, wound odor control, and promotes granulation that produces a clean base for total healing of the ulcer in a much shorter time than any formulae for this purpose heretofore.
    Type: Grant
    Filed: August 10, 1987
    Date of Patent: July 11, 1989
    Inventor: Morris Y. Mintz
  • Patent number: 4826841
    Abstract: The present invention is in alkanoyl anilides exhibiting insecticidal and arachnicidal activity, wherein the alkanoyl is both branched and substantially or totally fluorinated.
    Type: Grant
    Filed: March 5, 1986
    Date of Patent: May 2, 1989
    Assignee: Eli Lilly and Company
    Inventor: Robert P. Gajewski
  • Patent number: 4808572
    Abstract: Novel asymmetric thioethers of the formula ##STR1## in which the general symbols have the following meanings: a is an integer of from 1 to 7,R.sup.o represents hydrogen or C.sub.1-7 -alkanoyl,R.sup.1 represents C.sub.1-3 -alkyl which may be substituted at the terminal carbon atom by a free or acylated hydroxy group, by a halogen atom having an atomic number of at most 17, or by methoxy, or represents C.sub.1-3 -perfluoroalkyl,R.sup.2 represents an optionally unsaturated aliphatic radical having from 5 to 15 carbon atoms,A represents ethylene or alternatively, if R.sup.1 represents a halogenated radical and/or B represents phenylene or ethylene, a single bond or vinylene,B represents a single bond, ethynylene or phenylene,R.sup.3 represents hydroxy, C.sub.
    Type: Grant
    Filed: December 1, 1986
    Date of Patent: February 28, 1989
    Assignee: Ciba-Geigy Corporation
    Inventors: Andreas Beck, Werner Breitenstein, Andreas von Sprecher, Robert W. Lang, Konrad Oertle
  • Patent number: 4767781
    Abstract: A compound of the formula: ##STR1## wherein R.sub.1 is hydrogen, alkyl or acyl, R.sub.2 is hydroxy, alkoxy or amino, is useful as an antidiabetic agent.
    Type: Grant
    Filed: December 8, 1986
    Date of Patent: August 30, 1988
    Assignee: Takeda Chemical Industries, Ltd.
    Inventors: Susumu Shinagawa, Tsuneo Kanamaru, Setsuo Harada
  • Patent number: 4752615
    Abstract: A compound of the formula: ##STR1## useful as a fungicidal agent against phytopathogenic fungi, particularly their strains resistant to benzimidazole, thiophanate and/or cyclic imide fungicides.
    Type: Grant
    Filed: November 13, 1986
    Date of Patent: June 21, 1988
    Assignee: Sumitomo Chemical Company, Limited
    Inventors: Junya Takahashi, Toshiro Kato, Hiroshi Noguchi, Yukio Oguri, Shigeo Yamamoto, Katsuzo Kamoshita
  • Patent number: 4692468
    Abstract: This invention is directed to the use of a class of N-(2,2-difluoroalkanoyl)-o-phenylenediamines as an agent for the control of certain colonial insects, i.e., ants and termites.
    Type: Grant
    Filed: September 9, 1982
    Date of Patent: September 8, 1987
    Assignee: Eli Lilly and Company
    Inventor: Rudolph J. Boisvenue
  • Patent number: 4689344
    Abstract: A novel class of compounds has been found to be effective in blocking cholesterol and neutral lipid synthesis in-vivo without adversely affecting energy metabolism, useful for the treatment of obesity, hyperlipidemia and maturity-onset diabetes. The active compounds have the general formula ##STR1## or in-vivo hydrolyzable functional derivatives of the carboxylic groups thereof,whereinR.sub.1 and R.sub.2 each independently represents an unsubstituted or substituted hydrocarbyl or hetercyclyl radical;X and Y each independently represents hydrogen, optionally substituted lower alkyl, halogen, cyano, carboxy, lower alkoxycarbonyl or carbamoyl; andQ represents a diradical consisting of a linear chain of 8 to 14 carbon atoms, one or more of which may be replaced by heteroatoms, said chain being optionally substituted by inert substituents and one or more of said carbon or heteratom chain members optionally forming part of a ring structure.
    Type: Grant
    Filed: June 22, 1984
    Date of Patent: August 25, 1987
    Assignee: Epis S.A.
    Inventor: Jacob Bar-Tana
  • Patent number: 4654209
    Abstract: A preparation for percutaneous administration of nitroglycerine, said preparation comprising nitroglycerine incorporated in a cream base in an amount not less than about 0.05% by weight based on the total weight of the preparation. The composition may also contain other medicaments, the bioavailability of which is enhanced by the nitroglycerine. The action of the preparation against for example angina may be brought about by having an appropriate amount of nitroglycerine or as additional medicament another medicament active against angina. The preparation may contain an hydroxyalkylcellulose which may provide, in combination with a waxy component in the cream, for example a higher aliphatic alcohol, a prolonged release effect. The preparation has advantages particularly as regards bioavailability over prior uniphasic ointments.
    Type: Grant
    Filed: August 14, 1985
    Date of Patent: March 31, 1987
    Assignee: Euroceltique, S.A.
    Inventors: Stewart T. Leslie, Alan Rhodes, Cyril Boroda, Alfred Halpern
  • Patent number: 4647582
    Abstract: A compound of the formula: ##STR1## useful as a fungicidal agent against phytopathogenic fungi, and particularly against strains resistant to benzimidazole, thiophanate and/or cyclic imide fungicides.
    Type: Grant
    Filed: December 23, 1983
    Date of Patent: March 3, 1987
    Assignee: Sumitomo Chemical Company, Limited
    Inventors: Junya Takahashi, Toshiro Kato, Hiroshi Noguchi, Yukio Oguri, Shigeo Yamamoto, Katsuzo Kamoshita
  • Patent number: 4636505
    Abstract: Acylanilides of the formula ##STR1## wherein R.sup.1 and R.sup.2, the same or different, each is cyano, carbamoyl, nitro, halogeno, perfluoroalkyl or other defined substituents;R.sup.3 is hydrogen or halogen;R.sup.4 is hydrogen or alkyl, or is joined to R.sup.5 ;R.sup.5 is hydrogen, hydroxy, alkoxy or acyloxy or is joined to R.sup.4 ;R.sup.6 is alkyl or halogenoalkyl, or has the formula --A.sup.3 --R.sup.8 or --A.sup.4 --X.sup.2 --A.sup.5 --R.sup.9 ;A.sup.1 and A.sup.4, the same or different, each is alkylene;A.sup.2, A.sup.3 and A.sup.5, the same or different, each is a direct link or alkylene;X.sup.1 and X.sup.2, the same or different, each is oxygen, sulphur, sulphinyl, sulphonyl, imino or alkylimino;R.sup.7 and R.sup.9, the same or different, each is alkyl, alkenyl, hydroxyalkyl, cycloalkyl, phenyl optionally substituted, naphthyl or heterocyclic optionally substituted;and R.sup.8 is phenyl, naphthyl or heterocyclic as defined above for R.sup.7 or R.sup.
    Type: Grant
    Filed: July 15, 1983
    Date of Patent: January 13, 1987
    Assignee: Imperial Chemical Industries PLC
    Inventor: Howard Tucker
  • Patent number: 4540695
    Abstract: Aminonaphthacene derivatives of the formula: ##STR1## wherein A is either one of the following groups: ##STR2## wherein R.sup.1 is a hydrogen atom or a group of the formula: --COR.sup.7, R.sup.2 and R.sup.3 are each a lower alkoxy group or, when taken together, represent an ethylenedioxy group or an oxo group, R.sup.4 and R.sup.5 are both hydrogen atoms or either one of them is a hydrogen atom and the other is a group of the formula: --COR.sup.7, R.sup.6 is a hydrogen atom, a hydroxyl group or a group of the formula: --OCOR.sup.7 and R.sup.7 is a lower alkyl group, a halo(lower)alkyl group, a phenyl group or a halophenyl group, which are useful as anti-microbial and/or anti-tumor agents, or as intermediates in their production.
    Type: Grant
    Filed: August 11, 1982
    Date of Patent: September 10, 1985
    Assignee: Sumitomo Chemical Co., Ltd.
    Inventors: Kikuo Ishizumi, Naohito Ohashi, Michihisa Muramatsu
  • Patent number: RE33451
    Abstract: Gas transport agents such as artificial blood containing a perfluorocyclocarbon and an amine oxide are disclosed. These compositions have been found to provide transparent emulsions or solutions for use in oxygen transport, particularly in animals. Large concentrations of perfluorocarbons may be employed even up to 50% or more by volume in preparing emulsions, microemulsions or solutions. The emulsions or solutions have been found to be very stable at room temperature storage conditions thereby providing significant advantages.
    Type: Grant
    Filed: July 23, 1985
    Date of Patent: November 20, 1990
    Assignee: Children's Hospital Medical Center
    Inventor: Leland C. Clark, Jr.