Quaternary Ammonium Containing Patents (Class 514/642)
  • Patent number: 11998605
    Abstract: The present invention relates to an aqueous composition comprising: (i) a steroidal neuromuscular blocking agent that is a Rocuronium salt, further wherein the steroidal neuromuscular blocking agent is present at a concentration ranging from 5 mg/mL to 20 mg/mL based on the total volume of the aqueous composition; and (ii) an excipient that includes D-gluconic acid, D-glucono-delta-lactone, or a combination thereof, where the steroidal neuromuscular blocking agent and the excipient are dissolved in a solution consisting of water. Furthermore the present invention relates to a liquid pharmaceutical composition comprising or consisting of said aqueous composition and a method for producing said aqueous composition.
    Type: Grant
    Filed: July 18, 2019
    Date of Patent: June 4, 2024
    Assignee: B. Braun Melsungen AG
    Inventors: Juan Gil Béjar, Cristina Timoneda Ramia
  • Patent number: 11883527
    Abstract: The disclosure provides products configured for oral use and methods for preparing such products. In some embodiments, oral products described herein may comprise an active ingredient in an amount of 10 weight percent or less, a sugar alcohol, and a gum, such that the product is in the form of a pastille. In some embodiments, oral products described herein may comprise an active ingredient in an amount of about 10 weight percent or less, a sugar substitute, and a sugar alcohol syrup, such that the product is in the form of a lozenge.
    Type: Grant
    Filed: December 9, 2019
    Date of Patent: January 30, 2024
    Assignee: Nicoventures Trading Limited
    Inventors: Darrell Eugene Holton, Jr., Ronald K. Hutchens, Jeremy Barrett Mabe
  • Patent number: 11840499
    Abstract: A biobased fatty acid arginate may be synthesized according to the disclosed process by combining arginine and a fatty acid. The fatty acid arginate may have certain beneficial properties, such as surfactant properties or acting as an antimicrobial agent.
    Type: Grant
    Filed: February 26, 2021
    Date of Patent: December 12, 2023
    Assignee: The United States of America, as represented by The Secretary of Agriculture
    Inventors: Helen N Lew, Xuetong Fan, Kun Huang, Jianwei Zhang
  • Patent number: 11825841
    Abstract: Exemplary methods of and system for generating an antimicrobial wipe to clean and disinfect a surface contaminated with bacteria, viruses, spores, fungi, or combinations thereof. In some embodiments, the method includes applying non-thermal plasma to a moistened wipe to activate a liquid in the wipe. In some embodiments, the method includes applying non-thermal plasma to a liquid and then applying the activated liquid to a wipe. In one embodiment of a system for generating an antimicrobial wipe the system includes a housing having an opening; a supply of wipes disposed within the housing; a non-thermal plasma generator disposed within the housing; a power supply electrically coupled to the non-thermal plasma generator; and a feed system disposed within the housing, wherein the feed system moves one or more wipes from the supply of wipes past the plasma generator and out of the opening. As the feed system moves the wipes past the plasma generator, the plasma generator applies non-thermal plasma to the wipes.
    Type: Grant
    Filed: January 25, 2021
    Date of Patent: November 28, 2023
    Assignee: GOJO Industries, Inc.
    Inventors: Tsung-Chan Tsai, Jeffrey S. Louis, Daphne Pappas Antonakas, Sameer Kalghatgi, Robert L. Gray
  • Patent number: 11766429
    Abstract: A method of treating severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), otherwise known as COVID-19, infection by administering nicotinic receptor antagonists and/or PPAR-? agonists is presented. A combination of mecamylamine, or an isomer thereof, and pioglitazone synergistically reduces replication of SARS-CoV-2 in virus-infected cells and also synergistically reduces inflammatory cytokines such as IL-6, IL-?, and TNF?, which have been associated with SARS-CoV-2 infection.
    Type: Grant
    Filed: August 26, 2021
    Date of Patent: September 26, 2023
    Assignee: University of South Florida
    Inventors: Paul Ronald Sanberg, Christian Bernard Brechot, Shyam S. Mohapatra, Subhra Mohapatra
  • Patent number: 11723361
    Abstract: A sporicidal composition has a moderately low pH and includes at least one oxidizing acid and the dissociation product of at least one inorganic oxidizing agent. Very high effective solute concentrations can enhance the efficacy of the composition. Embodiments of the composition can be applied to a surface and allowed to absorb into the endospore, ultimately killing at least some of those bacteria in mature endospore form. The surface being treated can be an inanimate surface, particularly a hard surface, or a medical device.
    Type: Grant
    Filed: November 7, 2020
    Date of Patent: August 15, 2023
    Assignee: Next Science IP Holdings Pty Ltd
    Inventor: Matthew F. Myntti
  • Patent number: 11690802
    Abstract: The present invention is directed to an ophthalmic emulsion. The emulsion has a unique combination of ingredients that promotes the stability of small oil droplets within the emulsion. The emulsion also includes a mucoadhesive polymer that aid in delivering a lipid to the ocular surface.
    Type: Grant
    Filed: March 12, 2021
    Date of Patent: July 4, 2023
    Assignee: Alcon Inc.
    Inventors: Howard Allen Ketelson, David L. Meadows
  • Patent number: 11643621
    Abstract: Pre-moistened wipes that include one or more characteristics correlated to desired properties, such as high durability, mileage, cleaning composition retention, efficacy, or the like are described. Pulp substrates typically include an anionic charge, which can result in binding or retention of a cationic biocide such as a quaternary ammonium compound while the remainder of the composition is released from the wipe (e.g., through squeezing, wiping or other compression). The present wipes are specifically tailored to release at least 20% of the quaternary ammonium compound to a target surface, and exhibit at least a 3-log reduction in Staphylococcus aureus population within about 10 seconds to 5 minutes. Such release and efficacy is achieved without the presence of any cationic biocide release agent (e.g., latex or a cationic salt) included in the cleaning composition or elsewhere within the pre-loaded disinfecting wipe.
    Type: Grant
    Filed: March 12, 2021
    Date of Patent: May 9, 2023
    Assignee: THE CLOROX COMPANY
    Inventor: Nikhil P. Dani
  • Patent number: 11559531
    Abstract: The invention provides liquid formulation compositions and medicament delivery devices, and methods for preparing and using the same. For example, the liquid formulation composition is an emulsion including a solvent and liquid particles, which includes surfactants and are dispersed in the solvent. The volume average particle size of the liquid particles is less than about 100 ?m; the surface tension of the liquid formulation composition is less than about 60 mN/m; and the absolute value of zeta potential is greater than about 15 mV. The containment vessel may be a sprayer or a dropping device. The invention also provides methods for preparation of the liquid formulation compositions and medicament delivery devices as well as methods for using the same in treatment of various diseases and condition, for example, otitis media, otitis externa, rhinitis, sinusitis, lower respiratory tract inflammation, xerostomia (dry mouth), xerophthalmia (dry eyes) and xeromycteria (dry nose).
    Type: Grant
    Filed: July 10, 2021
    Date of Patent: January 24, 2023
    Assignee: Shenzhen HighTide Biopharmaceutical, Ltd.
    Inventors: Li Yu, James Gerry Ferguson
  • Patent number: 11377799
    Abstract: The present disclosure is generally directed to a mold inhibiting composition. The mold inhibiting composition can be used to treat various different substrates, including building material products, such as facing layers for wallboard. In general, any suitable paper product may be treated with the composition. The composition contains a mold inhibiting agent in combination with a defoamer. The mold inhibiting agent may comprise a pyrithione. The defoamer, on the other hand, may comprise an oil based defoamer containing metal oxide particles, such as silica particles. The mold inhibiting composition can be combined with a water repellent and applied to a substrate without excessive amounts of foam or froth being formed. The defoamer is selected so as to not interfere with the resulting water absorption properties of the product.
    Type: Grant
    Filed: February 18, 2021
    Date of Patent: July 5, 2022
    Assignee: ARXADA, LLC
    Inventors: Craig Waldron, Patrick Flaherty, Tyler Corse
  • Patent number: 11173207
    Abstract: The present invention provides methods and compositions for the stimulation of immune responses. In particular, the invention provides methods and compositions for enhancing an immune response to one or more antigens. Compositions and methods of the invention are useful for the treatment and/or prevention of microbial infections, such as infections caused by bacteria, viruses, fungi and parasites, as well as the treatment and/or prevention of cancer and malignant diseases. Compositions and methods of the invention include one or more antigens/immunogens together with an adjuvant formulation comprising an emulsion delivery system in combination with one or more immunostimulatory compounds (e.g., a compound that stimulates the innate immune system (e.g., a toll-like receptor antagonist (e.g., synthetic oligodeoxynucleotides (ODN)))) that enhance immune responses to the one or more antigens/immunogens when administered to a subject.
    Type: Grant
    Filed: May 19, 2017
    Date of Patent: November 16, 2021
    Assignees: THE REGENTS OF THE UNIVERSITY OF MICHIGAN, NANOBIO CORPORATION
    Inventors: James R. Baker, Jr., Douglas M. Smith, Susan Ciotti
  • Patent number: 11103464
    Abstract: The present invention relates to an aqueous composition for ophthalmological use or otolaryngological use, the aqueous composition containing: (A) a petrolatum; and two or more (B) nonionic surfactants.
    Type: Grant
    Filed: November 28, 2014
    Date of Patent: August 31, 2021
    Assignee: Rohto Pharmaceutical Co., Ltd.
    Inventors: Satoshi Yamaguchi, Kazuhiro Tsuji
  • Patent number: 10912296
    Abstract: The present invention provides a biocide formulation comprising a biocide in a micelle, wherein the micelle comprises a block copolymer having a biocide-solubilizing part and a water-soluble part, and a quaternary ammonium stabilizing compound. The present invention also provides a method for controlling microorganisms by eliminating and/or preventing biofilm formation in an aqueous environment.
    Type: Grant
    Filed: March 25, 2014
    Date of Patent: February 9, 2021
    Assignee: Kemira Oyj
    Inventors: Marko Kolari, Jukka Rautiainen, Hans-Peter Hentze, Hanna-Leena Alakomi, Pirkko Forssell
  • Patent number: 10314310
    Abstract: A new composition and method for cleaning hair grooming implements is provided. The composition comprises about 1.1% Sodium Hypochlorite, about 2.5% Sodium Hydroxide, about 0.5% Lithium Perchlorate and about 95.9% water. A concentrated version of the solution may be formed and later diluted for use.
    Type: Grant
    Filed: April 13, 2016
    Date of Patent: June 11, 2019
    Assignee: ZAE PRODUCTS & SERVICES LLC
    Inventors: Zoraida Encarnacion, Jiangyin Bao, Hansini Mundigala
  • Patent number: 9726652
    Abstract: A chemical indicator device for use in detecting exposure to an oxidizing agent, such as hydrogen peroxide, comprising a substrate or support upon which is disposed a chemical indicator composition (ink) for detecting an oxidizing agent, such as hydrogen peroxide. The chemical indicator composition further comprises an indicator dye that achieves a distinct range of different color changes with clear transitions between colors, upon exposure to different doses of the oxidizing agent, thus allowing for both a qualitative and semi-quantitative assessment of exposure to the agent.
    Type: Grant
    Filed: October 10, 2014
    Date of Patent: August 8, 2017
    Assignee: STERIS, INC.
    Inventors: Stephen Michael Lacy, Neil David Tyers
  • Patent number: 9539262
    Abstract: The present invention relates to a pharmaceutical composition suitable for ophthalmic use comprising one or more prostaglandin derivatives or salts, a stabilizing amount of polyethylene glycol hydroxystearate and pharmaceutically acceptable vehicle.
    Type: Grant
    Filed: April 20, 2015
    Date of Patent: January 10, 2017
    Assignee: SUN PHARMA ADVANCED RESEARCH COMPANY LTD.
    Inventors: Ajay Jaysingh Khopade, Arindam Halder, Subhas Balaram Bhowmick
  • Patent number: 9339028
    Abstract: The present invention provides a method for inhibiting microorganisms or plant pests using exfoliated clay/surfactant complex. The weight ratio of the exfoliated clay to the surfactant can range from 99/1 to 1/99. Preferably, the exfoliated clay is an inorganic layered clay on a nano scale and the surfactant is cationic, nonionic, anionic or amphoteric.
    Type: Grant
    Filed: July 2, 2013
    Date of Patent: May 17, 2016
    Assignee: NATIONAL TAIWAN UNIVERSITY
    Inventors: Jiang-Jen Lin, Ying-Chiao Wang, Pei-Ru Li
  • Patent number: 9164081
    Abstract: A method and a device for determining the emission of greenhouse gas, in particular methane, by ruminants, in particular dairy animals includes counting eructations (“belches”) of the animal. This is done by measuring a signal linked to the eructations, for example sound with a microphone. Given that the methane content of an eructation of this type is more or less constant, the total methane emission can be derived therefrom by counting.
    Type: Grant
    Filed: November 7, 2012
    Date of Patent: October 20, 2015
    Assignee: LELY PATENT N.V.
    Inventor: Patrick Philip Jacob Van Der Tol
  • Patent number: 9132071
    Abstract: Compositions containing quaternary ammonium compounds in which the nitrogen atom is substituted by at least one alkyl group having at least 12 carbon atoms, where composition includes at least 20% in weight by weight of the total composition, of ammonium halides in which the nitrogen atom is substituted by at least one alkyl group having at least 14 carbon atoms and more than 5%, preferably more than 7% in weight by weight of the total composition, of ammonium halides in which the nitrogen atom is substituted by at least one alkyl group having at least 16 carbon atoms. Ophthalmic oil-in-water emulsions containing such compositions, and the ophthalmic emulsions being are useful for eye care or for the treatment of eye conditions.
    Type: Grant
    Filed: January 30, 2008
    Date of Patent: September 15, 2015
    Assignee: SANTEN SAS
    Inventors: Laura Rabinovich-Guilatt, Gregory Lambert, Frederic Lallemand, Betty Philips
  • Patent number: 9056055
    Abstract: The subject of the present invention is a flavored therapeutic composition containing a clay as the active principle, and characterized in that the clay is a dioctahedral smectite and the flavor is encapsulated.
    Type: Grant
    Filed: February 12, 2014
    Date of Patent: June 16, 2015
    Assignees: IPSEN PHARMA S.A.S., FIRMENICH S.A.
    Inventors: Jérôme Barra, Denis Le Hazif
  • Patent number: 9028852
    Abstract: Antimicrobial compositions, especially those useful when applied topically, particularly to mucosal tissues (i.e., mucous membranes), including a cationic antiseptic such as biguanides and bisbiguanides such as chlorhexidine and its various salts including but not limited to the digluconate, diacetate, dimethosulfate, and dilactate salts; polymeric quaternary ammonium compounds such as polyhexamethylenebiguanide; silver and various silver complexes; small molecule quaternary ammonium compounds such as benzalkoium chloride and alkyl substituted derivatives; di-long chain alkyl (C8-C18) quaternary ammonium compounds; cetylpyridinium halides and their derivatives; benzethonium chloride and its alkyl substituted derivatives; and octenidine. The compositions can also include an enhancer component, a surfactant, a hydrophobic component, and/or a hydrophilic component.
    Type: Grant
    Filed: September 7, 2004
    Date of Patent: May 12, 2015
    Assignee: 3M Innovative Properties Company
    Inventor: Matthew T. Scholz
  • Publication number: 20150125496
    Abstract: The present application provides a dosage form and related methods for making the dosage form. The dosage form generally comprises a hydrophilic active ingredient, a plurality of solid, porous microcarriers, each having a hydrophobic surface, an optional hydrophobic encapsulant, and a hydrophilic delivery agent, wherein (i) the hydrophilic active ingredient is associated with the plurality of solid, porous microcarriers, (ii) the plurality of solid, porous microcarriers is encapsulated by the hydrophobic encapsulant, and (iii) the hydrophilic delivery agent is physically separated from a majority of the hydrophilic active ingredient by a boundary between the hydrophilic delivery agent and the hydrophobic encapsulant. In some embodiments, the dosage form is for topical application. In some additional embodiments, the plurality of solid, porous microcarriers is formed by modifying the microcarriers to increase their hydrophobicity.
    Type: Application
    Filed: November 4, 2014
    Publication date: May 7, 2015
    Inventor: Akira Yamamoto
  • Patent number: 8999399
    Abstract: The invention relates to a novel combined disinfection and decontamination agent comprising at least one vitamin, at least one metal ion, at least one active-surface compound, and at least one further antimicrobial active substance. The agent according to the invention surprisingly shows nearly complete nucleic acid disintegration in addition to an improved disinfectant effect. The agent can be successfully used as a combined decontamination and disinfection agent for skin, mucous membranes, hands, wounds, and/or hair, and instruments and surfaces of all kinds.
    Type: Grant
    Filed: November 14, 2009
    Date of Patent: April 7, 2015
    Assignee: Bose Chemie GmbH
    Inventors: Thomas Lisowsky, Sven Eggerstedt, Richard Bloss, Christiane Ostermeyer, Karlheinz Esser, Frank Bürger, Barbara Krug, Yvonne Feil, Kai-Martin Mueller, Delphine Haase
  • Patent number: 8999363
    Abstract: The present invention comprises methods and compositions for treating solid surfaces having antimicrobial and biocidal properties. Such surfaces are capable of controlling or killing a broad spectrum of biological agents, including viruses, bacteria and other microbial agents in solids, liquids or gases that subsequently contact the treated surface.
    Type: Grant
    Filed: November 15, 2006
    Date of Patent: April 7, 2015
    Assignee: Sishield Technologies, Inc.
    Inventor: Jacques Elfersy
  • Patent number: 8999357
    Abstract: The present invention provides a composition having disinfectancy & residual antimicrobial activity, where the antimicrobial composition comprises an organosilane quaternary compound and a quaternary ammonium compound and other formulations. Also provided are methods of disinfecting an article or providing an antimicrobial coating to an article using the same.
    Type: Grant
    Filed: February 7, 2006
    Date of Patent: April 7, 2015
    Assignee: Sishield Technologies, Inc.
    Inventors: Jacques Elfersy, Marcello D. Villahoz
  • Publication number: 20150094376
    Abstract: Disclosed is a method for inhibiting the excessive release of catecholamines of mammals infected by the enterovirus 71 (EV71), and more specially, a method for reversing the cardiopulmonary damages caused from EV71 infection in an animal model by using hexamethoniums. An early administration of a suitable amount of hexamethonium to the rats mimicking enterovirus 71 infection will attenuate the acute excessive release of catecholamines in the body of each rat. Thus, cardiac dysfunction and pulmonary edema generally caused by EV71 encephalitis is prevented and the survival rate of the rats increases.
    Type: Application
    Filed: October 1, 2014
    Publication date: April 2, 2015
    Inventors: Wen-Hsien Lu, Kai-Sheng Hsieh, Ching-Jiunn Tseng
  • Publication number: 20150079174
    Abstract: The invention relates to an antimicrobial surfactant complexed with a nanomaterial. The surfactant can be a quaternary ammonium cationic surfactant which is coated on the surface of a nanomaterial such as a silica nanoparticle or a carbon nanotube.
    Type: Application
    Filed: April 19, 2013
    Publication date: March 19, 2015
    Inventors: Lino Da Silva Ferreira, David José Roxo Botequim, João Reina Maia E Silva
  • Publication number: 20150064288
    Abstract: The present invention relates to an anti-microbial composition and method of use thereof. In particular, the present invention relates to an anti-microbial composition comprising farnesol and cetrimide.
    Type: Application
    Filed: September 8, 2014
    Publication date: March 5, 2015
    Inventor: John Found
  • Publication number: 20150065579
    Abstract: Described are novel polycationic polyhydroxyl compounds and their uses in personal care compositions.
    Type: Application
    Filed: March 26, 2013
    Publication date: March 5, 2015
    Inventor: Deavenport L. Joseph
  • Publication number: 20150038441
    Abstract: The invention relates to a kit-in-part comprising of a composition for the use as a cleaning and treating of ears of a companion animal and suitable packaging material, wherein the kit-in part additionally consists of components selected from the group of a pharmaceutical composition for use in the treatment of otitis externa, application and dosage information, cannules, cotton swabs, gauzes and information about the cleaning and maintenance ears of a companion animal.
    Type: Application
    Filed: December 21, 2011
    Publication date: February 5, 2015
    Applicant: BOEHRINGER INGELHEIM VETMEDICA GMBH
    Inventors: Joachim Karle, Reinhard Seffner
  • Patent number: 8940792
    Abstract: An aqueous composition adapted to kill bacteria in both planktonic and biofilm states is lethal toward a wide spectrum of gram positive and gram negative bacteria as well as other microbes. The composition, which is slightly to moderately acidic, includes a significant amount of one or more surfactants and large amounts of osmotically active solutes. The composition can be applied directly to a site of bacterial growth. Even when the bacteria is in biofilm form, the surfactant component(s) begin to kill the bacteria before the macromolecular matrix is removed or dislodged from the site.
    Type: Grant
    Filed: November 16, 2012
    Date of Patent: January 27, 2015
    Assignee: Next Science, LLC
    Inventor: Matthew Franco Myntti
  • Patent number: 8933128
    Abstract: The invention relates to the use of a composition for treating the surfaces of livestock buildings and/or the material therein in order to eliminate and/or inhibit pathogenic protozoa, and in particular coccidiosis oocysts. According to the invention, said composition essentially comprises the combination of an alkylamine and of a quaternary ammonium or of a quaternary ammonium derivative.
    Type: Grant
    Filed: February 5, 2009
    Date of Patent: January 13, 2015
    Assignee: CID Lines N.V.
    Inventors: Richard Alasri, Koen Brutsaert
  • Publication number: 20150001066
    Abstract: A wipe for anti-microbial disinfecting includes a flexible substrate and an anti-microbial ion source integrated on the substrate. The flexible substrate is made entirely or in part of woven fiber cloth, non-woven fiber cloth, woven synthetic cloth, non-woven synthetic cloth, or natural fiber cloth. The anti-microbial ion source is configured to dissolve in an aqueous solution to form an anti-microbial solution. The flexible substrate is configured to absorb the anti-microbial solution for use in cleaning.
    Type: Application
    Filed: June 25, 2014
    Publication date: January 1, 2015
    Inventor: Ashok V. Joshi
  • Publication number: 20140363475
    Abstract: An oil-in-water emulsion skin cosmetic composition comprising the following components (A), (B), (C), (D) and (E): (A) from 1 to 10% by mass of an oil agent which is liquid at 25° C., (B) from 1 to 6% by mass of an oil agent which is solid or semi-solid at 25° C., (C) from 0.7 to 3.5% by mass of linear alcohol having 12 to 22 carbon atoms, (D) from 0.2 to 1% by mass of at least one selected from the group consisting of an ionic surfactant and a nonionic surfactant having an HLB of 12.5 to 15, and (E) water, wherein the mass ratio of the component (B) to the component (A), (B)/(A), is from 0.3 to 1.0, and emulsion particles have a number-average particle diameter of 1.0 to 3.0 ?m.
    Type: Application
    Filed: June 6, 2014
    Publication date: December 11, 2014
    Applicant: KAO CORPORATION
    Inventors: Takashi TANISHIMA, Aki YUYAMA, Shinichi TSUKII
  • Publication number: 20140357723
    Abstract: A commercially-suitable tricholine nasal formulation for administration to a human as a nasal spray is disclosed. The tricholine nasal formulation includes an aqueous solution of tricholine citrate, a volatile oil and a buffer system. The disclosed tricholine nasal formulation possesses an acceptable odor and a reasonable shelf-life. The tricholine nasal formulation may be used to treat the symptoms associated with stress, anxiety, depression, malaise, or “burn out” syndrome. Optionally, a moisturizer is included in the composition to alleviate any dryness resulting from administration of the formulation to a user. A preservative may be included in the composition to produce a longer shelf-life.
    Type: Application
    Filed: May 29, 2013
    Publication date: December 4, 2014
    Inventor: Uwe-Bernd Bernd Ross
  • Publication number: 20140348944
    Abstract: This invention relates to a “high lower alcohol content”(>40% v/v of a C1-4 alcohol) liquid composition able to be dispensed as a stable foam with the use of non-propellant foam dispensing devices from non-pressurized containers. The liquid compositions comprise an alcohol, C1-4 (>40% v/v), a silicone-based surfactant of at least 0.001% by weight to prepare a foamable composition, 0-10% w/w of additional minor components added to obtain the desired performance (a foamable composition), and the balance being purified water. The compositions may include emulsifier-emollients and moisturizers, secondary surfactants, foam stabilizers, fragrances, antimicrobial agents, other type of medicinal ingredients, and the like ingredients or additives or combinations thereof commonly added to alcohol gels or foams, aerosol compositions or to toiletries, cosmetics, pharmaceuticals and the like.
    Type: Application
    Filed: February 24, 2014
    Publication date: November 27, 2014
    Applicant: Deb Worldwide Healthcare Inc.
    Inventors: Maria Teresa Fernandez de Castro, Bruce Michael Koivisto, Francisco Munoz
  • Patent number: 8895473
    Abstract: Present invention provides an aqueous composition made from selected biochemical substances that will help with the low temperature tolerance of plants and thus to avoid “chilling injury” and to promote better recovery from such injury, when the solution is applied to crop plants prior to the arrival of cold snap or period of low temperature.
    Type: Grant
    Filed: April 5, 2012
    Date of Patent: November 25, 2014
    Assignee: CH Biotech R&D Co., Ltd.
    Inventors: Denny Ng, Kai Xia
  • Publication number: 20140343157
    Abstract: The present invention relates to sanitizing compositions containing glycerin ether ethoxylate solfactant compounds and cationic active antimicrobial agents containing quaternary ammonium groups. Beneficially the compositions provide sanitizing efficacy without diminished performance requiring either increased concentrations of sanitizing agent and/or increased contact time for surfaces treated with the compositions. The compositions are suitable for use as antimicrobials and/or sanitizing agents in various formulations and methods of employing the same.
    Type: Application
    Filed: July 30, 2014
    Publication date: November 20, 2014
    Inventors: Gregory G. Griese, Carter M. Silvernail, David D. McSherry
  • Patent number: 8889679
    Abstract: Provided are biocidal compositions comprising glutaraldehyde and a compound selected from the group consisting of 1-(3-chloroallyl)-3,5,7-triaza-1-azoniaadamantane; tris(hydroxymethyl)-nitromethane; and a hexahydrotriazine compound. The compositions are useful for controlling microorganisms in aqueous or water-containing systems.
    Type: Grant
    Filed: May 21, 2010
    Date of Patent: November 18, 2014
    Assignee: Dow Global Technologies LLC
    Inventor: Bei Yin
  • Patent number: 8889194
    Abstract: Disclosed is a compound and methods for use by an individual attempting to reduce or cease tobacco smoking or one exposed to environmental tobacco smoke. The compound includes a first component blocking nicotine receptor sites to reduce nicotine cravings or withdrawal symptoms, a second component increasing serotonin levels and acting synergistically with the first component to reduce nicotine cravings or withdrawal symptoms, assisting in maintaining body weight and reducing increased stress and anxiety, and a third component acting synergistically with the first and/or second component to reduce nicotine cravings or withdrawal symptoms, maintain body weight, and/or reduce increased stress and anxiety. The third component comprises a supplement that replenishes depleted body substance(s), repairs damaged body substance(s), and/or ameliorates the impaired function of body substance(s). Some combination of the first, second, and third component alters the perceived taste of tobacco smoke.
    Type: Grant
    Filed: September 29, 2010
    Date of Patent: November 18, 2014
    Inventor: Harlan Clayton Bieley
  • Patent number: 8889592
    Abstract: The present invention relates to boosting the action of crop protection compositions comprising in particular spiroheterocyclically substituted tetramic acid derivatives of the formula (I) by addition of ammonium or phosphonium salts and optionally penetrants, to the corresponding compositions, to processes for their preparation and to their use in crop protection as insecticides and/or acaricides and/or for preventing unwanted vegetation.
    Type: Grant
    Filed: April 20, 2011
    Date of Patent: November 18, 2014
    Assignee: Bayer CropScience AG
    Inventors: Reiner Fischer, Stefan Lehr, Olga Malsam, Rolf Pontzen, Elmar Gatzweiler, Rainer Sussmann
  • Publication number: 20140336260
    Abstract: A novel product for mold prevention and treatment is disclosed herein. The product comprises water, one or more anti-mold agents, one or more water-soluble fluoropolymers or other water-soluble polymers with similar properties, and one or more emulsifiers. In some embodiments, the product may further comprise one or more preservatives, one or more stabilizers, one or more binders, one or more fining agents, one or more firming agents, one or more thickeners, and/or one or more clarifying agents. The product may be non-toxic, biodegradable, effective for a long-period of time and against a wide variety of molds, and may also provide other features which render it safe for the environment as compared to other commonly used products in mold prevention and treatment.
    Type: Application
    Filed: July 24, 2014
    Publication date: November 13, 2014
    Inventors: Freddy Kai Klaffmo, Bert Jonny Nilsson, Britt Ann-Christine Langselius
  • Publication number: 20140335206
    Abstract: This invention concerns a synergistic combination of a topical anesthetic and wound barrier forming agent capable of providing extended analgesia of ‘significant open wounds’ (that being, for example, a laceration, surgical incision, abrasion, ulcer or burn, but not being a minor cut, scratch, sting, burn or abrasion) in which conventional management alternatives (such as suturing and/or administration of injected or systemic analgesia) are impractical, unaffordable or otherwise unavailable.
    Type: Application
    Filed: July 25, 2014
    Publication date: November 13, 2014
    Inventors: Meridith Sheil, Allan Giffard, Charles R. Olsson
  • Patent number: 8883192
    Abstract: Compositions useful for weight management in an animal are disclosed. The compositions comprise one or more isoflavones or isoflavone metabolites, and in some embodiments include conjugated linoleic acid, and/or L-carnitine. Also disclosed are methods useful for weight management in an animal utilizing compositions comprising one or more isoflavones, conjugated linoleic acid, and/or L-carnitine. Preferably, the compositions and methods employ a combination of one or more isoflavones, or a combination of one or more isoflavones in conjunction with conjugated linoleic acid, and L-carnitine.
    Type: Grant
    Filed: June 4, 2012
    Date of Patent: November 11, 2014
    Assignee: Nestec S.A.
    Inventor: Yuanlong Pan
  • Patent number: 8865641
    Abstract: A method of treating a fatty liver disease in a subject. The method comprises administering to the subject an effective amount of a cholinergic pathway stimulating agent, wherein the fatty liver disease is selected from non-alcoholic fatty liver (NAFL), alcoholic fatty liver (AFL), non-alcoholic steatohepatitis (NASH), alcoholic steatohepatitis (ASH), NASH-associated liver fibrosis, ASH-associated liver fibrosis, non-alcoholic cirrhosis, and alcoholic cirrhosis.
    Type: Grant
    Filed: June 14, 2012
    Date of Patent: October 21, 2014
    Assignee: The Feinstein Institute for Medical Research
    Inventors: Valentin A. Pavlov, Kevin J. Tracey
  • Patent number: 8859464
    Abstract: Embodiments of the present invention disclose an agricultural composition that is a field ready spray or a tank mix that includes at least one nitrogen containing isethionic acid salt, at least one agriculturally active ingredient, and at least one surfactant.
    Type: Grant
    Filed: April 23, 2010
    Date of Patent: October 14, 2014
    Assignee: Huntsman Petrochemical L LC
    Inventors: R. Scott Tann, Howard M. Stridde
  • Patent number: 8857741
    Abstract: A topical spray composition and a system for containing and applying the composition is described. The composition has liquid emulsifiers that unexpectedly result in a superior product suitable to be applied homogeneously.
    Type: Grant
    Filed: April 27, 2012
    Date of Patent: October 14, 2014
    Assignee: Conopco, Inc.
    Inventors: Thomas Nikolaos Morikis, Kathleen Lynn Malacarne, Gee-Young Ng
  • Patent number: 8846732
    Abstract: Biogenic sulfide production is synergistically inhibited by treating sulfate-reducing bacteria (SRB) with a biocide and a metabolic inhibitor. The biocide directly kills a first portion of the SRB. The metabolic inhibitor inhibits sulfate-reducing growth of a second portion of the SRB without directly killing the second portion of the SRB. The treatment of SRB with both a biocide and a metabolic inhibitor provides effective biogenic sulfide inhibition at significantly lower concentrations than would be required if the biocide or metabolic inhibitor was used alone.
    Type: Grant
    Filed: October 6, 2010
    Date of Patent: September 30, 2014
    Assignees: ConocoPhillips Company, University Technologies International, Inc.
    Inventors: Gary E. Jenneman, Anne Greene, Gerrit Voordouw
  • Publication number: 20140288180
    Abstract: A novel product for mold prevention and treatment is disclosed herein. The product comprises water, one or more anti-mold agents, one or more polymers, and one or more emulsifiers. In some embodiments, the product may further comprise one or more preservatives, one or more stabilizers, one or more binders, one or more fining agents, one or more firming agents, one or more thickeners, and/or one or more clarifying agents. The product may be non-toxic, biodegradable, effective for a long-period of time and against a wide variety of molds, and may also provide other features which render it safe for the environment as compared to other commonly used products in mold prevention and treatment.
    Type: Application
    Filed: June 3, 2014
    Publication date: September 25, 2014
    Applicant: Miraculum Applications AB
    Inventors: Freddy Kai Klaffmo, Bert Jonny Nilsson, Britt Ann-Christine Langselius
  • Publication number: 20140274962
    Abstract: Described herein are methods of inhibiting or reversing the progression of presbyopia in an eye by administering a ?L-crystallin electrostatic interaction inhibitor. Presbyopia is caused by aggregation of the soluble crystalline lens proteins called the crystallins, particularly ?L-crystallin. It has been found that the aggregation of ?L-crystallin is an electrostatic phenomenon and that electrostatic interaction inhibitors can be employed to prevent the formation of ?L-crystallin aggregates as well as to deaggregate already formed aggregates.
    Type: Application
    Filed: May 9, 2014
    Publication date: September 18, 2014
    Applicant: UNIVERSITY OF MASSACHUSETTS
    Inventors: Murugappan Muthukumar, Zhaoyang Ou, Deniz Civay