The Aryl Ring Or Aryl Ring System Is Bonded Directly To Another Ring Or Ring System Patents (Class 514/650)
  • Enhanced soft tissue flap survival in reconstructive surgery
    Patent number: 4599340
    Abstract: A method for reducing soft tissue flap necrosis in a patient undergoing reconstructive surgery is disclosed. The method comprises administering to such patient an effective amount of a calcium channel blocking drug or a pharmaceutically acceptable non-toxic salt thereof to reduce said necrosis of said flap. Also disclosed are pharmaceutical compositions suitable for use in reducing soft tissue flap necrosis.
    Type: Grant
    Filed: May 7, 1985
    Date of Patent: July 8, 1986
    Assignee: Miles Laboratories, Inc.
    Inventors: Lester Silver, Barry Goldenberg
  • Anticonvulsants
    Patent number: 4590063
    Abstract: Compounds of the formula ##STR1## where R is a methyl, ethyl or propyl group and n is 1 or 2 and their nontoxic salts are useful as anticonvulsants.
    Type: Grant
    Filed: April 25, 1985
    Date of Patent: May 20, 1986
    Assignee: Adria Laboratories, Inc.
    Inventors: John P. Carter, Jr., Richard L. Wolgemuth
  • Binary compositions of penbutolol and furosemide or piretanide
    Patent number: 4564625
    Abstract: Salts formed between penbutolol and furosemide or piretanide, pharmaceutical compositions containing such salts, and methods for treating diseases of the coronary and circulatory systems with such salts.
    Type: Grant
    Filed: May 10, 1984
    Date of Patent: January 14, 1986
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Roman Muschaweck, Werner Fulberth, Alfred Sickmuller
  • Substituted 1-oxo-2-phenyl-2-(2-alkylaminoethyl)-1,2,3,4-tetrahydronaphthalenes, their preparation and their use
    Patent number: 4564641
    Abstract: 1-Oxo-2-phenyl-2-(2-alkylaminoethyl)-1,2,3,4-tetrahydronaphthalenes of the formula I ##STR1## where R.sup.1 and R.sup.2 are identical or different and are each hydrogen, halogen, trifluoromethyl, C.sub.1 -C.sub.4 -alkyl or C.sub.1 -C.sub.4 -alkoxy, R.sup.3 is C.sub.1 -C.sub.6 -alkyl and R.sup.4 is hydrogen, C.sub.1 -C.sub.6 -alkyl or benzyl, or R.sup.3 and R.sup.4 together may furthermore be a C.sub.2 -C.sub.5 -alkylene chain, and their salts with physiologically tolerated acids, and their preparation, are described.The novel compounds are useful active compounds for treating disorders.
    Type: Grant
    Filed: November 22, 1983
    Date of Patent: January 14, 1986
    Assignee: BASF Aktiengesellschaft
    Inventors: Werner Seitz, Hans-Jurgen Teschendorf, Alfred Michel, Martin Traut, Hans P. Hofmann, Horst Kreiskott