Alicyclic Ring Containing Patents (Class 514/690)
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Publication number: 20110009495Abstract: The present invention relates to a novel application of a compound. The compound 4-hydroxy-2,3-dimethoxy-6-methyl-5-(3,7,11-trimethyl-dodeca-2,6,10-trienyl)-cyclohex-2-enone of the invention is isolated and purified from the extracts of Antrodia camphorata, which can be applied for inhibiting the survival of bone cancer cells and be used as a pharmaceutical composition to inhibit the bone tumor growth.Type: ApplicationFiled: July 8, 2010Publication date: January 13, 2011Applicant: Golden Biotechnology CorporationInventors: Sheng-Yun Liu, Wu-Che Wen, Mao-Tien Kuo
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Publication number: 20110009494Abstract: The present invention relates to a novel application of a compound. The compound 4-hydroxy-2,3-dimethoxy-6-methyl-5-(3,7,11-trimethyl-dodeca-2,6,10-trienyl)-cyclohex-2-enone of the invention is isolated and purified from the extracts of Antrodia camphorata, which can be applied for inhibiting the survival of pancreatic cancer cells and be used as a pharmaceutical composition to inhibit the pancreatic tumor growth.Type: ApplicationFiled: July 8, 2010Publication date: January 13, 2011Applicant: GOLDEN BIOTECHNOLOGY CORPORATIONInventors: Sheng-Yun Liu, Wu-Che Wen, Mao-Tien Kuo
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Publication number: 20110008475Abstract: The present invention relates to novel emulsions of mint oil and/or L-carvone and the use thereof for the fungicidal treatment of field crops or products thereof.Type: ApplicationFiled: November 10, 2008Publication date: January 13, 2011Inventor: Alberto Sardo
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Publication number: 20110003694Abstract: The present invention relates to a novel method of treating bulbs or tubers with L-carvone and/or mint oil by thermal fogging.Type: ApplicationFiled: November 10, 2008Publication date: January 6, 2011Inventor: Alberto Sardo
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Publication number: 20110002905Abstract: The present invention relates to compositions containing one or more proteins, one or more polysaccharides and one or more fat-soluble active ingredients and their use for the enrichment, fortification and/or coloration of food beverages, animal feed and/or cosmetics.Type: ApplicationFiled: February 23, 2010Publication date: January 6, 2011Applicants: DSM IP ASSETS B.V., FUDAN UNIVERSITYInventors: Chyi-Cheng CHEN, Ping Yao, Bruno H. Leuenberger, Gerhard Wagner, Keke Xu, Shi-Kchen Chen
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Publication number: 20100330212Abstract: A skin-sensitizing formulation is provided in an edible, softgel pill. A person engaged in a sexual activity bites down on the pill, thereby effectuating the oral release of the skin-sensitizing formulation. This allows the skin-sensitizing formulation to be spread to a sexual partner, on any part of the skin or sexual region of the body preferably through oral contact with the partner. The skin-sensitizing substance is spread to the partner directly on the skin or through oral contact or beneath a condom worn by the partner. The skin-sensitizing formulation may include an essential mint oil, analog or derivative, and may further includes an enhancer, rubefacient, counterirritant, anesthetic, K-Opoid Receptor activator, or TRPM8 activator. Various inactive ingredients are also disclosed.Type: ApplicationFiled: June 29, 2010Publication date: December 30, 2010Inventor: Amy Grosso-Piacentino
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Publication number: 20100323996Abstract: The present invention relates to a cosmetic composition for the cleaning of the skin, said composition comprising or consisting of one or more compounds of formula (I) wherein represents a single bond or double bond; R1 and R2 are independently selected from H, linear or branched C1 to C4 alkyl, linear or branched C1 to C4 alkenyl, linear or branched C1 to C4 alkinyl, and linear or branched C1 to C4 alkanoyl; R4 is selected from H, linear or branched C1 to C4 alkyl, linear or branched C1 to C4 alkenyl, and linear or branched C1 to C4 alkinyl; and R3 and R5 are independently selected from H, OH and halogen, or R3 and R5 together are O to form an epoxid, wherein represents a single bond in case R3 and R5 together are O. Also provided are means and methods for the prevention or reduction of biofilm formation on an intracorporeal device and/or for the removal of biofilm from an intracorporeal device, wherein said biofilm comprises or consists of bacteria of the genus Propionibacterium.Type: ApplicationFiled: February 18, 2009Publication date: December 23, 2010Applicant: Biotechnology Research and Information Network (B.R.A.I.N.)Inventors: Dechert Ute, Eck Jurgen, Krohn Michael
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Publication number: 20100317742Abstract: As described below, the present invention provides methods and compositions for controlling a honey bee parasitic mite. In addition, the invention features compositions useful for the treatment or prevention of a parasitic mite infestation in a honey bee hive.Type: ApplicationFiled: August 2, 2010Publication date: December 16, 2010Inventor: Gene Probasco
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Patent number: 7838565Abstract: A preventive and/or therapeutic agent for diabetes complications, which comprises as an effective ingredient a cyclohexenone long-chain alcoholic derivative represented by the following formula (1): wherein, R1, R2 and R3 each independently represents a hydrogen atom or a methyl group and X represents a linear or branched C10-28 alkylene or alkenylene group. The cyclohexenone long-chain alcoholic derivative of the present invention significantly suppresses a reduction in a peripheral nerve conduction rate and alleviates the hypofunction of the bladder so that it is useful as a preventive and/or therapeutic agent for diabetes complications, particularly, for diabetic neuropathy.Type: GrantFiled: February 15, 2002Date of Patent: November 23, 2010Assignee: Meiji Dairies CorporationInventors: Masao Miyagawa, Takeshi Watanabe, Motoaki Saito, Bang Luu, Masashi Yamada, Hiroto Suzuki
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Publication number: 20100291057Abstract: Provided is a composition for reducing oxidative stress and/or side effects occurring during cancer chemotherapy or improving a nutritional status during cancer chemotherapy. The composition is one for reducing oxidative stress and/or side effects occurring during cancer chemotherapy or improving nutritional status during cancer chemotherapy and comprises the following components (a) to (f): (a) an antioxidant agent; (b) at least one component selected from the group consisting of vitamin B1, vitamin B2, vitamin B6, niacin, and pantothenic acid; (c) at least one component selected from the group consisting of folic acid, vitamin B12, and vitamin A; (d) zinc; (e) selenium; and (f) coenzyme Q10.Type: ApplicationFiled: January 6, 2009Publication date: November 18, 2010Applicant: NUTRI CO., LTD.Inventor: Susumu Kawaguchi
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Publication number: 20100285155Abstract: The present invention is directed to anti-microbial cleanser compositions comprising linalool, hinokitiol and dipropylene glycol. The present invention further provides methods for using these compositions to maintain eyelid hygiene, to treat an ocular disorder or to clean a skin surface. The cleanser compositions of the present invention can be in the form of a foam, gel or liquid.Type: ApplicationFiled: April 30, 2010Publication date: November 11, 2010Applicant: ADVANCED VISION RESEARCH, INC.Inventors: Jeffrey Gilbard, Elisabeth Gilbard, Yanick Douyon, Robert B. Huson
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Patent number: 7829555Abstract: The invention provides a method of targeting a drug to areas of hypoxic and/or ischemic tissue within the body in which the desired drug species is linked to a non-cytotoxic bioreductive carrier. Also provided by the invention are novel bioreductive conjugates comprising a non-cytotoxic bioreductive moiety with linked-thereto at least one therapeutic agent. The compounds of the invention are particularly suitable for the treatment of rheumatoid arthritis and other arthritic conditions, diabetes, atherosclerosis, stroke, sepsis, Alzheimer's disease and other neurological disorders, cancer, kidney disease, digestive diseases, liver disease, chronic periodontitis or ischemia following tissue transplantation.Type: GrantFiled: February 13, 1998Date of Patent: November 9, 2010Assignee: The University of ManchesterInventors: David Blake, Declan Naughton, Ged Adams, Margaret Adams, legal representative, Ian Stratford, Christopher Morris, Mohammed Jaffar, Matthew Naylor
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Publication number: 20100280130Abstract: The present invention relates to approaches, methods, pharmaceuticals and uses directed to the curative treating or preventing of Primary Progressive Multiple Sclerosis (PP-MS), by using 2,3-dimethoxy-5-methyl-6-(10-hydroxydecyl)-1,4-benzoquinone (Idebenone) as the active agent.Type: ApplicationFiled: April 28, 2010Publication date: November 4, 2010Applicants: SANTHERA PHARMACEUTICALS (SCHWEIZ) AG, The U.S.A., as represented by the Secretary, Department of Health and Human ServicesInventors: Thomas Meier, Bibiana Bielekova, Henry F. McFarland
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Publication number: 20100279963Abstract: Derivatives of dicarbonyl compounds having antitumor and antibiotic activity which can be used as anticancer agents.Type: ApplicationFiled: July 1, 2010Publication date: November 4, 2010Applicant: Abraxis BioScience, LLCInventors: Chunlin Tao, Qinwei Wang, Vuong Trieu, Neil Desai, Patrick Soon-Shiong
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Publication number: 20100273893Abstract: The present invention refers to thymoquinone, a main constituent of the volatile oil of Nigella sativa, and its protective effect against sepsis syndrome morbidity, mortality and associated organ dysfunctions. In particular, the present invention refers to thymoquinone for use in the prevention and/or treatment of sepsis syndrome. The present invention further refers to a pharmaceutical composition and a kit.Type: ApplicationFiled: September 16, 2009Publication date: October 28, 2010Inventors: Khalid M. Alkharfy, Nasser M. Al-Daghri, Omar S. Al-Attas, Majed S. Alokail
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Publication number: 20100273894Abstract: The present invention relates to methods of treating Leber's hereditary optic neuropathy and dominant optic atrophy with tocotrienol quinones, including alpha-tocotrienol quinone, in order to alleviate symptoms of the disease.Type: ApplicationFiled: April 27, 2010Publication date: October 28, 2010Inventor: Guy M. MILLER
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Patent number: 7820153Abstract: cis-Jasmone has been discovered to be useful as a semiochemical that changes the behavior of insects and/or the physiology of plants. It has direct signalling roles with plant-feeding aphids, in attraction of aphid predators and parasitoids, and may act as an airborne signal inducing production of volatile plant semiochemicals, including the monoterpene (E)-?-ocimene, that stimulate foraging by parasitoids. It is an extremely benign compound having, to human beings, a pleasant aroma and gives a long-lasting effect after removal of the stimulus.Type: GrantFiled: November 24, 2004Date of Patent: October 26, 2010Assignee: Plant Bioscience LimitedInventors: Alastair James Hick, John Anthony Pickett, Lester John Wadhams, Johnathan Andrew Napier
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Publication number: 20100267838Abstract: The present invention relates to pulverulent compositions of at least one carotenoid selected from the group consisting of ?-carotene, astaxanthin, canthaxanthin, citranaxanthin, lycopene and lutein, a process for the production of these pulverulent compositions, and the use of the pulverulent compositions.Type: ApplicationFiled: November 11, 2008Publication date: October 21, 2010Applicant: BASF SEInventor: Christian Köpsel
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Patent number: 7811597Abstract: An article, such as a container or bag for garbage, which repels animals such as cats, dogs, rats, and crows. The article may be made from a synthetic resin composition including a synthetic resin and from 10 to 15,000 ppm by weight of a salicylic acid ester, menthol and/or camphor. The article may also be made from a synthetic resin composition including a synthetic resin and an odorant composition containing eucalyptus oil and one or more of a salicylic acid ester, menthol and camphor.Type: GrantFiled: September 26, 2005Date of Patent: October 12, 2010Assignee: JAD Corporation of AmericaInventors: Masahiko Katoh, Joseph Dussich
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Publication number: 20100249222Abstract: A method for treating skin, reducing oxidative damage to a skin cell, reducing lipoxygenase (LO) activity in a skin cell, reducing cyclooxygenase (COX) activity in a skin cell, reducing tumor necrosis factor alpha (TNF-?) in a skin cell, or reduction matrix metalloproteinase enzyme activity in a skin cell comprising contacting skin or a skin cell with an aromatic skin-active ingredient.Type: ApplicationFiled: June 9, 2010Publication date: September 30, 2010Applicant: Mary Kay Inc.Inventors: Bob Walke, Cristi Gomez, Tiffany C. Florence, Michelle D. Hines
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Publication number: 20100247504Abstract: A powder composition, includes: (A) an oil-soluble antioxidant substance powder; (B) a water-soluble antioxidant substance powder; and (C) thioctic acid.Type: ApplicationFiled: September 3, 2008Publication date: September 30, 2010Applicant: FUJIFILM CORPORATIONInventor: Fumitaka Ueda
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Publication number: 20100239552Abstract: This invention is directed to pharmaceutical combinations comprising an antioxidant agent, an anti-inflammatory agent, and optionally at least one other anti-diabetic agent useful for treating metabolic disorders. This invention also encompasses pharmaceutically acceptable compositions comprising an antioxidant agent, an anti-inflammatory agent, optionally at least one other anti-diabetic agent, and at least one pharmaceutically acceptable carrier.Type: ApplicationFiled: March 16, 2010Publication date: September 23, 2010Applicant: GENMEDICA THERAPEUTICS SLInventors: Eric Mayoux, Luc Marti Clauzel, Silvia Garcia-Vicente, Marta Serrano Munoz, Antonio Zorzano Olarte, Alec Mian
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Publication number: 20100226877Abstract: cis-Jasmone has been discovered to be useful as a semiochetnical that changes the behaviour of insects and/or the physiology of plants. It has direct signalling roles with plant-feeding aphids, in attraction of aphid predators and parasitoids, and may act as an airborne signal inducing production of volatile plant semiochemicals, including the monoterpene (E)-?-ocimene, that stimulate foraging by parasitoids. It is an extremely benign compound having, to human beings, a pleasant aroma and gives a long-lasting effect after removal of the stimulus.Type: ApplicationFiled: May 18, 2010Publication date: September 9, 2010Applicant: PLANT BIOSCIENCE LTD.Inventors: Alastair James Hick, John Anthony Pickett, Lester John Wadhams, Johnathan Andrew Napier
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Publication number: 20100227009Abstract: The present invention is directed to pest-controlling compositions comprising as active ingredients one or more ?-diones, particularly ?-diketones and ?-triketones, and to the use of these compositions inter alia for preventing, eradicating, destroying, repelling or mitigating harmful, annoying or undesired pests including insects, arachnids, helminths, molluscs, protozoa and viruses. The present invention is further directed to processes of preparing ?-diones by de novo synthesis or from natural sources such as volatile oil-bearing plants from families including Alliaceae, Apiaceae, Asteraceae, Cannabinaceae, Lamiaceae, Pteridaceae, Myrtaceae, Myoporaceae, Proteaceae, Rutaceae and Zingiberaceae.Type: ApplicationFiled: May 18, 2010Publication date: September 9, 2010Applicants: BIOPROSPECT LIMITED, UNIVERSITY OF WESTERN SYDNEYInventors: Robert Neil Spooner-Hart, Albert Habib Basta
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Publication number: 20100222262Abstract: Compositions and methods for reducing cardiovascular risk utilizing substituted 1,3-cyclopentadione compounds are described.Type: ApplicationFiled: April 2, 2009Publication date: September 2, 2010Applicant: METAPROTEOMICS, LLCInventors: Veera Konda, Anu Desai, Matthew L. Tripp, Gary K. Darland, Joseph Lamb, Jeffrey S. Bland, Dennis A. Emma
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Publication number: 20100216876Abstract: An antidiarrhetic composition is provided which is efficacious against diarrhea, in particular, the predominant secretory diarrhea; an antidiarrhetic medicinal composition containing the same is also provided; a food containing the antidiarrhetic composition is also provided; and a method of preventing diarrhea using the same is also disclosed. The composition for relieving diarrhea is a cool composition capable of acting on the digestive tract in the recipient's body and inhibiting the secretion of the intestinal Cl?. In other words, a composition containing one or more kinds of cool act compounds. It may be provided by adding to medicines, foods or drinks.Type: ApplicationFiled: October 2, 2008Publication date: August 26, 2010Inventors: Yuichi Suzuki, Kenya Ishida
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Publication number: 20100209497Abstract: The present disclosure provides for a scientific formulation useful in the treatment and prevention of human and animal diseases. A biologically effective amount of each of the components of the formulation is administered to patients in pill (or capsule) form via multiple different and identifiable pills. The compounds of the formulation are segregated into different pill types, and contain various amounts of the compounds Curcumin, Genistein, Squalamine, Vitamin E, N-Acetyl-Cysteine, Methylselenocysteine, Zinc Gluconate, B Complex, Lentinen, Coenzyme Q10 Acetyl-L-Carnitine, Lipoic Acid, Resveratrol, and Vitamin C. Furthermore, Arabinoxylan and/or Peperine may be added to the various pill formulations.Type: ApplicationFiled: February 19, 2009Publication date: August 19, 2010Inventor: Jerry T. Thornthwaite
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Publication number: 20100184857Abstract: The invention provides hops (Humulus lupulus) extracts or derivatives thereof for use in treating a patient prophylactically and/or therapeutically for ulcerogenic-type disorders of the stomach and/or intestines. The ulcerogenic disorders can be of the type chemically induced, environmentally-induced, infection-induced, and/or stress-induced. The invention also provides a pharmaceutical composition comprising an active amount of hops extracts or derivatives thereof, in combination with an analgesic compound and/or an anti-inflammatory compound. The invention further provides for use of hops extracts or derivatives thereof, significantly reducing and/or therapeutically treating ulcerogenic-type disorders of the stomach and/or intestines.Type: ApplicationFiled: September 22, 2009Publication date: July 22, 2010Applicant: METAPROTEOMICS, LLCInventors: John G. Babish, Matthew L. Tripp, Jeffrey S. Bland, Terrence Howell, Gary K. Darland, Robert H. Lerman, Daniel O. Lukaczer
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Patent number: 7758884Abstract: The absorption and deposition of carotenoids added to poultry diets into the yolk of eggs produced by the poultry is improved by adding a carotenoid formulation comprising a carotenoid, a vegetable oil, a surfactant, a chelating agent, an antioxidant, an alkali and a solvent. The carotenoid formulation can reduce the crystalline nature of lutein for its better dissolution in the formulation and the diet. This new formulation is capable of making more micelles for an effective transfer of lutein from the formulations to the aqueous layer. The new formulation can increase the bioavailability of lutein in chicken biological system and leads to more deposition in the blood and the egg. The lutein deposition in the egg was consistent for an extended period of time when this new formulation was added to the diet. Addition of this carotenoid formulation to the diet increased the antioxidant power of the blood. Eggs produced by poultry fed diets supplemented by the formulation have in excess of 0.Type: GrantFiled: January 28, 2005Date of Patent: July 20, 2010Assignee: Kemin Industries, Inc.Inventors: Leow Sai Kaw, Goh Swee Keng, Jesuadimai Ignatius Xavier Antony, Hai Meng Tan
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Publication number: 20100172875Abstract: The present invention concerns the use of an oil-in-water emulsion where the interior of oil droplets exhibit interfaces, between lipophilic domains and hydrophilic or amphiphilic domains, due to the presence of a lipophilic additive solubilized inside the oil droplets and which is used for delayed release of active elements such that the release of at least one active element, which has a octanol/water partitioning coefficient logP higher than ?1, corresponds to a higher Tmax than the Tmax obtained for the simple reference oil-in-water emulsion where no lipophilic additive is used.Type: ApplicationFiled: May 30, 2008Publication date: July 8, 2010Applicant: NESTEC S.A.Inventors: Van Anh Phan, Nicolas Godinot, Laurent Sagalowicz, Martin Leser, Fabien Robert
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Publication number: 20100173024Abstract: Described herein are the results of comprehensive genetic expression and other molecular analysis of the effect of antioxidants on biological systems, including specifically different human cells. Based on these analyses, methods and compositions are described for modifying or influencing the lifespan of cells, tissues, organs, and organisms. In various embodiments, there are provided methods for modulating the activity of the gene maintenance process in order to influence the length and/or structural integrity of the telomere in living cells, as well as methods for modulating the rate/efficiency of the cellular respiration provided by the mitochondria, mitochondrial biogenesis, and maintenance of the mitochondrial membrane potential.Type: ApplicationFiled: December 1, 2009Publication date: July 8, 2010Inventor: David H. McDaniel
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Publication number: 20100168249Abstract: The invention provides a composition containing reduced coenzyme Q10, which is useful as a pharmaceutical product, food, cosmetic, animal drug, feed, and the like, as well as a stabilization method thereof. The oxidation of reduced coenzyme Q10 into oxidized coenzyme Q10 by molecular oxygen can be suppressed by setting, in a composition containing reduced coenzyme Q10 and at least one kind of oil component selected from the group consisting of fat, oil, a mixture thereof, fatty acid, wax and a surfactant, the weight ratio of the reduced coenzyme Q10 to the oil component to not less than 1/4 when the composition is a liquid, and not less than 1/9 when the composition is a solid.Type: ApplicationFiled: February 23, 2010Publication date: July 1, 2010Applicant: KANEKA CORPORATIONInventors: Shiro KITAMURA, Takahiro UEDA
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Publication number: 20100160422Abstract: There is provided a halogen-containing organosulfur compound having an excellent controlling effect on arthropod pests represented by the formula (I): wherein, m represents 0, 1 or 2, n represents 0, 1 or 2, A represents optionally substituted C3-C7 cycloalkyl or optionally substituted C5-C7 cycloalkenyl group, Q represents a C1-C5 haloalkyl group containing at least one fluorine atom, or a fluorine atom, R1 and R3 independently represent optionally substituted C1-C4 chain hydrocarbon, halogen or hydrogen, R2 and R4 independently represent optionally substituted C1-C4 chain hydrocarbon, —C?C(=G)R5, cyano, halogen or hydrogen, G represents oxygen or sulfur, and R represents optionally substituted C1-C4 alkyl, hydroxyl, optionally substituted C1-C4 alkoxy, optionally substituted C3-C6 alkenyloxy, optionally substituted C3-C6 alkynyloxy, amino, optionally substituted C1-C4 alkylamino, optionally substituted di(C1-C4 alkyl)amino, C2-C5 cyclic amino or hydrogen.Type: ApplicationFiled: June 26, 2008Publication date: June 24, 2010Applicant: SUMITOMO CHEMICAL COMPANY, LIMITEDInventor: Hiromasa Mitsudera
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Publication number: 20100144888Abstract: Methods for using pesticidal compositions containing a pesticidally acceptable carrier, at least one GABA receptor modulator compound as a pesticidally active ingredient and optionally an additional compounds, such as a synergist, and methods for using same.Type: ApplicationFiled: August 18, 2009Publication date: June 10, 2010Applicant: ECOSMART TECHNOLOGIES, INC.Inventor: Steven M. BESSETTE
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Publication number: 20100137449Abstract: Compounds and methods for multi-targeted protein kinase modulation for angiogenesis, cancer treatment or the inflammatory pathways associated with those conditions are disclosed. The compounds and methods disclosed are based on substituted 1,3-cyclopentadione compounds.Type: ApplicationFiled: December 10, 2008Publication date: June 3, 2010Applicant: METAPROTEOMICS, LLCInventors: Matthew L. Tripp, John G. Babish, Jeffrey S. Bland, Veera Konda, Anu Desai, Gary Darland, Brian J. Carroll, James S. Traub, Linda M. Pacioretty, Dennis Emma
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Publication number: 20100130619Abstract: The invention describes use of an injectable form of Idebenone, suitable for intravenous injection or infusion. The proposed formulation is an oil-in-water emulsion, where Idebenone is associated with the oil droplets.Type: ApplicationFiled: November 24, 2008Publication date: May 27, 2010Inventors: Joseph Schwarz, Michael Weisspapir
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Publication number: 20100111888Abstract: Disclosed are compounds having the ability to modulate, namely to improve, enhance and or modify fragrance compositions due to their ability to inhibit cytochrome P450 enzymes, e.g. CYP2A13 and CYP2B6.Type: ApplicationFiled: March 20, 2008Publication date: May 6, 2010Applicant: GIVAUDAN SAInventors: Boris Schilling, Thierry Granier, Georg Frater, Andreas Hanhart
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Publication number: 20100113460Abstract: Disclosed are compounds having the ability to inhibit cytochrome P450 2A6, 2A13, and/or 2B6 and tobacco products comprising them. Also disclosed are pharmaceutical compositions comprising them.Type: ApplicationFiled: March 20, 2008Publication date: May 6, 2010Applicant: Givaudan SAInventors: Boris Schilling, Wolf D. Woggon, Antoinette Chougnet, Thierry Granier, Georg Frater, Andreas Hanhart
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Publication number: 20100098752Abstract: Compositions and methods for administering one or more antioxidants to a human subject have been developed. The antioxidant-containing lipid vesicles of the invention provide a delivery system for antioxidants which can be applied topically to the skin.Type: ApplicationFiled: January 18, 2008Publication date: April 22, 2010Inventor: Mark A. Pinsky
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Publication number: 20100093677Abstract: The current invention is directed to methods of inducing the negative chemotaxis of a migratory cell comprising contacting the cell with a compound selected from the group consisting of idebenone, benazepril, rolipram, moxonidine, lamivudine, loxoprofen, terbinafine, Synephrine, 6-aminoindazole, and a Vitamin D analog, or a pharmaceutically acceptable salt of any of thereof.Type: ApplicationFiled: October 9, 2009Publication date: April 15, 2010Inventor: Erica Brook Goodhew
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Publication number: 20100092560Abstract: The present invention aims to propose a particulate composition containing reduced coenzyme Q10, which simultaneously shows high oxidative stability and high absorbability in the body and a production method thereof, as well as a stabilizing method thereof, to be used in the fields of foods, foods with nutrient function claims, foods for specified health uses, nutritional supplements, nutritional products, animal drugs, beverages, feeds, cosmetics, pharmaceuticals, therapeutic drugs, prophylactic drugs and the like.Type: ApplicationFiled: October 15, 2009Publication date: April 15, 2010Applicant: KANEKA CORPORATIONInventors: Shinsuke Akao, Takashi Ueda, Takahiro Ueda, Yozo Nagira, Hideyuki Kishida
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Publication number: 20100093870Abstract: The present invention relates to A composition obtained from the lipid soluble extract of rhizomes and leaves of Curcuma species of Zingiberaceae family, useful for the treatment of neurocerebrovascular disorders, said composition comprising fraction A consisting of ar-turmerone of formula 1, and turmerone of formula 2, and/or along with fraction B consisting of curcumene and zingiberine, and/or fraction C consisting of germacrone, curcumerone, zedoarone, sedoarondiol, isozdedoaronidiol, curcumenone, and curlone, and/or pharmaceutically acceptable additives and a method of treating neurocerebrovascular disorders in animals including humans using said composition by administering therapeutically effective amount of lipid soluble extract.Type: ApplicationFiled: May 18, 2009Publication date: April 15, 2010Inventors: Madhur Ray, Raghwendra Pal, Satyawan Singh, Nandoo Mal Khanna
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Patent number: 7691297Abstract: In a process for the manufacture of beadlet preparations of fat-soluble substances in a water-soluble or water-dispersible non-gelling matrix, an aqueous emulsion of the fat-soluble substance(s) and the matrix component are fed through a spray nozzle in the upper section of a vertical spray tower. Through separate inlets powderous starch and a stream of hot air are also fed in the upper section of the vertical spray tower. A stream of cold air is fed in the lower section of the spray tower so as to form a fluidised bed of starch-covered beadlets comprising the matrix component as well as the fat-soluble substances. The beadlets are collected from the fluidised bed and are discharged to a dryer.Type: GrantFiled: January 6, 2004Date of Patent: April 6, 2010Assignee: DSM IP Assets B.V.Inventor: David Schaffner
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Publication number: 20100080862Abstract: It is intended to provide compositions and foods for use in the treatment, prophylaxis, or amelioration of diseases or symptoms which can be treated, prevented or ameliorated by activating PPAR, in particular, insulin resistant diabetes and hyperlipidemia. Namely, medicinal compositions usable in treating, preventing or improving diseases or symptoms which can be treated, prevented or ameliorated by activation PPAR which contain humulones, isohumulones or lupulones or pharmaceutically acceptable salts or solvates thereof.Type: ApplicationFiled: September 10, 2009Publication date: April 1, 2010Inventors: Hiroaki YAJIMA, Yutaka Miura, Daisuke Fujiwara, Hideharu Odai, Keiji Kondo, Hajime Nozawa
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Publication number: 20100076090Abstract: A topical anti-aging skin care formulation comprising an effective amount of a benzoquinone, such as CoQ10, plus a synergistic pair of stabilizers and a synergistic pair of whiteners. The stabilizers are octyl salicylate and octyl methoxycinnamate. The whiteners are titanium dioxide and zinc oxide. When proper amounts of these ingredients are used in an aqueous based emulsion formulation, the product will be initially white, and will remain white for an extended period of time.Type: ApplicationFiled: September 22, 2008Publication date: March 25, 2010Inventor: Louise Holyfield
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Publication number: 20100056621Abstract: The present invention relates to agonists of the hTAS2R14 bitter taste receptor and its role in bitter taste transduction. The invention also relates to assays for screening molecules that modulate, e.g. suppress or block hTAS2R14 bitter taste transduction or bitter taste response.Type: ApplicationFiled: April 20, 2005Publication date: March 4, 2010Applicant: Deutsches Institut fur ErnahrungsforschungInventors: Maik Behrens, Anne Brockhoff, Bernd Bufe, Christina Kuhn, Wolfgang Meyerhof, Marcel Winnig
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Publication number: 20100048686Abstract: It is an object of the present invention to discover that a perfume can change a person's temperature sense and humidity sense, to identify a perfume component that can change temperature sense, and to provide a perfume composition for controlling temperature sense that contains this perfume component, and to a sense control method or sense control article such as an aromatic or a cosmetic that is beneficial for controlling temperature sense, and to a perfume map for selecting a perfume suited to controlling temperature sense. The perfume composition is characterized in that a perfume component that changes the temperature subjectively sensed by a person (temperature sense) is contained, and that the perfume component that changes the temperature sense is a perfume component identified on the basis of a temperature image obtained from test subject assessment.Type: ApplicationFiled: August 24, 2009Publication date: February 25, 2010Applicant: SHISEIDO CO., LTD.Inventors: Ken Shoji, Sumie Taguchi, Yushi Terajima
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Publication number: 20090306218Abstract: An antimicrobial formulation containing a synergistic combination of a quinone, such as an optionally substituted benzoquinone or hydroquinone, and a bismuth salt. The formulation may in particular be used against propionibacteria, more particularly to treat skin and skin structure conditions such as acne, or against microbial infections within the oral cavity.Type: ApplicationFiled: September 21, 2007Publication date: December 10, 2009Inventors: Daniel James Fitzgerald, Priscila Gottardello
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Publication number: 20090298950Abstract: The present invention relates to campholytic aldehyde condensates of formula (I) wherein R1-R5 have the same meaning as given in the specification. It furthermore relates to a method of their production and to fragrance compositions and fragrance applications comprising them.Type: ApplicationFiled: August 7, 2007Publication date: December 3, 2009Inventors: Jerzy A. Bajgrowicz, Urs Mueller
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Publication number: 20090291919Abstract: Methods are disclosed for treating ophthalmic conditions related to the production of toxic visual cycle products that accumulate in the eye, and are associated with reactions of the visual cycle during medical procedures that expose the eye to light, most commonly the various forms of ophthalmic surgery. Compounds and compositions useful in the these methods, either alone or in combination with other therapeutic agents, are also described, along with methods of screening for new agents useful in said treatments.Type: ApplicationFiled: January 21, 2009Publication date: November 26, 2009Applicant: University of Florida Research Foundation, Inc.Inventors: Shalesh Kaushal, Syed M. Noorwez