Carboxylic Acid Or Salt Thereof Patents (Class 514/784)
  • Patent number: 10653647
    Abstract: Compositions are provided that contain a TRPV1 agonist, such as capsaicin, and a solvent system. Topical application of the composition results in rapid delivery of agonist to the dermis and epidermis. Method of using the compositions for reducing nociceptive nerve fiber function in subjects, and for treatment of capsaicin-responsive conditions are also provided.
    Type: Grant
    Filed: August 1, 2017
    Date of Patent: May 19, 2020
    Assignees: GRT US Holding, Inc., Grünenthal GmbH
    Inventors: Naweed Muhammad, Gene Curtis Jamieson, Keith R. Bley, Sanjay Chanda
  • Patent number: 10576047
    Abstract: Formulations and methods are provided for the treatment of pain, and neuropathic pain in particular. The formulations are eutectic mixtures of a capsaicinoid and a local anesthetic agent and/or an anti-pruritic agent.
    Type: Grant
    Filed: August 20, 2018
    Date of Patent: March 3, 2020
    Assignee: Grünenthal GmbH
    Inventor: Manoj Maniar
  • Patent number: 10265333
    Abstract: The present invention relates to a lipid nanomaterial containing lysophosphatidylcholine or an ether derivative thereof, a method for preparing the same, a method for reducing erythrocyteolysis and hemagglutination using the compound, and a pharmaceutical agent containing the lipid nanomaterial. The present invention contains lysophosphatidylcholine or an ether derivative thereof as an active ingredient, and can be useful as a treatment agent for septicemia, bacterial infection diseases, and the like.
    Type: Grant
    Filed: March 11, 2014
    Date of Patent: April 23, 2019
    Assignee: ARIBIO CO., LTD.
    Inventors: Jai Jun Choung, Myung Hwa Kim, Du Jin Seol, Sae Kwang Ku, Soo Hyun Sung, Young Sam Kim
  • Patent number: 9962445
    Abstract: The present invention relates to a pharmaceutical composition in form of emulsion or microemulsion and the use thereof as aid during endoscopic procedures in which it is injected in a target tissue in order to form a cushion. More in details, the invention relates to a method for performing an endoscopic procedure, which comprises injecting said pharmaceutical composition in form of emulsion or microemulsion in a target tissue of a patient, in order to form a cushion, which cushion is then optionally subjected to an endoscopic surgical procedure, such as a resection.
    Type: Grant
    Filed: October 26, 2016
    Date of Patent: May 8, 2018
    Assignee: COSMO TECHNOLOGIES LTD.
    Inventors: Luigi Moro, Luigi Maria Longo, Enrico Frimonti, Alessandro Repici
  • Patent number: 9872514
    Abstract: The present invention provides edible compositions comprising a compound of the present invention, food products comprising such edible compositions and methods of preparing such food products. The present invention also provides methods of reducing the amount of NaCl in a food product, methods of reducing the sodium intake in a diet, and methods of reducing bitter taste in a food product.
    Type: Grant
    Filed: June 9, 2016
    Date of Patent: January 23, 2018
    Assignee: Chromocell Corporation
    Inventors: Kambiz Shekdar, Daniel Lavery, Joseph Gunnet, Jessica Langer, Jane V. Leland, David Hayashi, Peter H. Brown, Louise Slade, William P. Jones
  • Patent number: 9655990
    Abstract: The present invention relates to an anti-aging antimicrobial wound healing polymer based hydrogel. In the study of the present invention, a wound healing gel formulation is developed by combining poloxamer polymers and boron component at adequate concentrations in a carbopol based gel. The said gel exhibits fast action on the damaged area and prevents scar formation.
    Type: Grant
    Filed: April 8, 2014
    Date of Patent: May 23, 2017
    Assignee: YEDITEPE UNIVERSITESI
    Inventors: Fikrettin Sahin, Selami Demirci, Aysegul Dogan
  • Patent number: 9522216
    Abstract: The present invention relates to a pharmaceutical composition in form of emulsion or microemulsion and the use thereof as aid during endoscopic procedures in which it is injected in a target tissue in order to form a cushion. More in details, the invention relates to a method for performing an endoscopic procedure, which comprises injecting said pharmaceutical composition in form of emulsion or microemulsion in a target tissue of a patient, in order to form a cushion, which cushion is then optionally subjected to an endoscopic surgical procedure, such as a resection.
    Type: Grant
    Filed: May 13, 2016
    Date of Patent: December 20, 2016
    Assignee: COSMO TECHNOLOGIES LTD.
    Inventors: Luigi Moro, Luigi Maria Longo, Enrico Frimonti, Alessandro Repici
  • Patent number: 9364580
    Abstract: The present invention relates to a pharmaceutical composition in form of emulsion or microemulsion and the use thereof as aid during endoscopic procedures in which it is injected in a target tissue in order to form a cushion. More in details, the invention relates to a method for performing an endoscopic procedure, which comprises injecting said pharmaceutical composition in form of emulsion or microemulsion in a target tissue of a patient, in order to form a cushion, which cushion is then optionally subjected to an endoscopic surgical procedure, such as a resection.
    Type: Grant
    Filed: November 24, 2015
    Date of Patent: June 14, 2016
    Assignee: COSMO TECHNOLOGIES LTD.
    Inventors: Luigi Moro, Luigi Maria Longo, Enrico Frimonti, Alessandro Repici
  • Publication number: 20150141526
    Abstract: The present invention relates to a pharmaceutical composition in form of emulsion or microemulsion and the use thereof as aid during endoscopic procedures in which it is injected in a target tissue in order to form a cushion. More in details, the invention relates to a method for performing an endoscopic procedure, which comprises injecting said pharmaceutical composition in form of emulsion or microemulsion in a target tissue of a patient, in order to form a cushion, which cushion is then optionally subjected to an endoscopic surgical procedure, such as a resection.
    Type: Application
    Filed: November 18, 2014
    Publication date: May 21, 2015
    Applicant: COSMO TECHNOLOGIES LTD.
    Inventors: Luigi MORO, Luigi Maria LONGO, Enrico FRIMONTI, Alessandro REPICI
  • Publication number: 20150133567
    Abstract: The present invention aims to provide a production method of a composition containing (A) glycerol and (B) glycine, which includes using glycerol substantially free of dihydroxyacetone or having a dihydroxyacetone content of not more than 150 ppm. According to the present invention, a composition, particularly a cosmetic composition, having a moist feeling but free of stickiness and showing suppressed coloration can be provided.
    Type: Application
    Filed: November 11, 2014
    Publication date: May 14, 2015
    Applicant: AJINOMOTO CO., INC.
    Inventor: Rina YUMIOKA
  • Publication number: 20150126616
    Abstract: N-methyl-N-acylglucamines are suitable as thickening agents in aqueous surfactant solutions containing one or more anionic surfactants of the group including alkyl ether sulfates and alkyl sulfates, the N-methyl-N-acylglucamines containing at least 60 wt.-% of N-methyl-N-acylglucamines that have a C12-, C14-acyl group or an unsaturated C18-acyl group and at the same time less than 5 wt.-% of N-methyl-N-acylglucamines that contain an acyl group <C12. The surfactant solutions are particularly used in cosmetic compositions.
    Type: Application
    Filed: May 29, 2013
    Publication date: May 7, 2015
    Applicant: Clariant Finance (BVI) Limited
    Inventors: Peter Klug, Carina Mildner
  • Patent number: 9023372
    Abstract: The present invention relates to nanoparticles comprising a metallic core with a surface coating, wherein the coating comprises at least an excitable radiative molecule attached thereto or impregnated therein, and wherein the excitable molecule is positioned at a sufficient distance from metallic core to enhance emissions when excited. The nanoparticles are included in compositions that may be used for surface coatings, cosmetics, assays, flow velocity measurements and targeting of tissue.
    Type: Grant
    Filed: January 18, 2008
    Date of Patent: May 5, 2015
    Assignee: University of Maryland
    Inventor: Chris D. Geddes
  • Patent number: 9012521
    Abstract: An object of the present invention is to provide a gel containing pyrroloquinoline quinone that is capable of easily forming a gel near room temperature and is useful even in the food sector, and a method for producing the gel. According to the present invention, there is provided a gel containing pyrroloquinoline quinone that uses pyrroloquinoline quinone itself as a gelling agent and a method for producing the gel by adding a salt of pyrroloquinoline quinone to water and subsequently adjusting the temperature or the pH to reduce solubility.
    Type: Grant
    Filed: August 9, 2011
    Date of Patent: April 21, 2015
    Assignee: Mitsubishi Gas Chemical Company, Inc.
    Inventors: Tsuyoshi Mikekado, Kazuto Ikemoto, Hajime Shimizu
  • Patent number: 9005663
    Abstract: An exemplary embodiment of the invention is a method for making silver nanoparticles, and includes steps of reacting a silver salt with a phosphene amino acid to make silver nanoparticles. Exemplary phosphene amino acids include trimers, with a particular example being a trimeric amino acid conjugate containing one phosphene group. In an exemplary method of the invention, the silver nanoparticles may be produced in timer periods of less than about 30 minutes, and at temperatures of less than about 40° C. Other methods of the invention are directed to methods for stabilizing silver nanoparticles.
    Type: Grant
    Filed: August 31, 2004
    Date of Patent: April 14, 2015
    Assignee: The Curators of the University of Missouri
    Inventors: Kannan Raghuraman, Kattesh K. Katti
  • Publication number: 20150099809
    Abstract: Many fragrances that provide a scent of freshness tend to be highly volatile and are therefore not very economical when used in typical applications such as washing or cleaning processes, so they have to be used in relatively large quantities to be able to produce adequate effects. The disclosed photolabile pro-fragrances provide a much longer-lasting sense of fragrance, in particular with a scent of freshness, when used in typical applications, thus allowing said fragrances to be used efficiently.
    Type: Application
    Filed: December 15, 2014
    Publication date: April 9, 2015
    Inventors: Thomas Gerke, Christian Kropf, Ursula Huchel, Axel Griesbeck, Agnieszka Landes
  • Publication number: 20150093440
    Abstract: A method of making aggregate particles suitable for a powder aerosol composition that includes forming a dispersion of nanoparticulate drug and/or excipient in a non-aqueous liquid, and spray-drying the dispersion to generate aggregate particles having a mass median aerodynamic diameter of less than or equal to about 100 microns, and particles generated by such method, and compositions of said particles.
    Type: Application
    Filed: October 13, 2011
    Publication date: April 2, 2015
    Applicant: GLAXO GROUP LIMITED
    Inventors: Michiel M. Van Oort, John N. Hong
  • Publication number: 20150094382
    Abstract: The present invention is directed to isolated microorganisms as well as strains and mutants thereof, biomasses, microbial oils, compositions, and cultures; methods of producing the microbial oils, biomasses, and mutants; and methods of using the isolated microorganisms, biomasses, and microbial oils.
    Type: Application
    Filed: December 10, 2014
    Publication date: April 2, 2015
    Inventors: Joseph W. PFEIFER, III, Jon Milton HANSEN, Jose R. GARCIA, Xiao Daniel DONG, Paul Warren BEHRENS, Kirk E. APT
  • Publication number: 20150087726
    Abstract: A cosmetic transparent gel preparation that has high levels of transparency and hardness and favorable usability, as well as a gelling agent that is ideal for use in the cosmetic transparent gel preparation. The cosmetic transparent gel preparation contains an esterification reaction product obtained by reacting glycerol with a dibasic acid of 18 to 28 carbon atoms and a fatty acid of 8 to 28 carbon atoms (excluding dibasic acids), 12-hydroxystearic acid, and an oil component. The gelling agent contains an esterification reaction product obtained by reacting glycerol with a dibasic acid of 18 to 28 carbon atoms and a fatty acid of 8 to 28 carbon atoms (excluding dibasic acids), and 12-hydroxystearic acid.
    Type: Application
    Filed: November 19, 2013
    Publication date: March 26, 2015
    Applicant: THE NISSIN OILLIO GROUP, LTD.
    Inventor: Keiichi Oyama
  • Publication number: 20150072926
    Abstract: The invention relates to pharmaceutical compositions comprising a first type of granules and a second type of granules, wherein said first type of granules comprises a salt of N-(8-(2-hydroxybenzoyl)amino)caprylic acid and no GLP-1 peptide, and wherein said second type of granules comprises a GLP-1 peptide and no salt of N-(8-(2-hydroxybenzoyl)amino)caprylic acid, as well as the intermediate granules, processes for the preparation of the granules and compositions, and use thereof in medicine.
    Type: Application
    Filed: March 15, 2013
    Publication date: March 12, 2015
    Inventors: Thomas Vilhelmsen, Helle Eliasen, Tue Hansen
  • Patent number: 8956646
    Abstract: In various embodiments, the present invention provides zwitterionic lipids, encapsulants incorporating these zwitterionic lipids and such encapsulants encapsulating one or more bioactive agent. An exemplary bioactive agent is a nucleic acid. Also provided are pharmaceutical formulations of the encapsulants and methods of using such formulations to deliver a bioactive agent to a subject in treating or diagnosing disease in that subject.
    Type: Grant
    Filed: August 15, 2011
    Date of Patent: February 17, 2015
    Assignee: The Regents of the University of California
    Inventors: Francis C. Szoka, Jr., Colin Walsh, Vincent Venditto, Juliane Nguyen, Emily Perttu
  • Publication number: 20150044297
    Abstract: The invention relates to a novel galenical system for taste masking, protecting an active substance, in particular in an acid medium, modulating releasing properties, masking mucous irritability and toxicity of certain active substances, for preparing aqueous forms which have a masked taste, are stable and pH independent. Said invention also relates, in particular to a galenical system which is embodied in the form of lipidic solid particles and strictly hydrophobic and devoid of water, surface active agents, emulsifiers, solvent traces and which is characterized in that it comprises at least one type of hydrophobic wax and at least one type of fatty non-neutralised acid.
    Type: Application
    Filed: October 27, 2014
    Publication date: February 12, 2015
    Inventors: Karim Ioualalen, Rose-Anne Raynal
  • Publication number: 20150045295
    Abstract: A breath-powered, dry powder inhaler, a cartridge, and a pulmonary drug delivery system are provided. The dry powder inhaler can be provided with or without a unit dose cartridge for using with the inhaler. The inhaler and/or cartridge can be provided with a drug delivery formulation comprising, for example, a diketopiperazine and an active ingredient, including, peptides and proteins such as insulin and glucagon-like peptide 1 for the treatment of diabetes and/or obesity. The dry powder inhaler is compact; can be provided in various shapes and sizes, colors, and comprises a housing, a mouthpiece, a cartridge placement area, and a mechanism for opening and closing the medicament cartridge. The device is easy to manufacture, provides a pre-metered single unit dose, it is relatively easy to use, and can be reusable or disposable.
    Type: Application
    Filed: October 21, 2014
    Publication date: February 12, 2015
    Inventors: Chad C. Smutney, P. Spencer Kinsey, Carl R. Sahi, Benoit Adamo, John M. Polidoro, Scott McLean, Dennis Overfield, Kelly S. Kraft, Karla Somerville
  • Publication number: 20150031606
    Abstract: The invention relates to granules and pharmaceutical compositions comprising a salt of N-(8-(2-hydroxybenzoyl)amino)caprylic acid and a lubricant obtained by mixing hereof for more than 5 minutes prior to granulation as well as processes for their preparation and use thereof in medicine.
    Type: Application
    Filed: March 15, 2013
    Publication date: January 29, 2015
    Inventor: Thomas Vilhelmsen
  • Publication number: 20150030684
    Abstract: An irrigation resistant bone repair composition including a biocompatible or bioactive bone repair material and a mixture of non-random poly(oxyalkylene) block copolymers is described. Also, methods for treating a bone having a bone gap or a bone defect with the composition including a biocompatible or bioactive bone repair material and a mixture of non-random poly(oxyalkylene) block copolymers are also provided. Also, kits including the irrigation resistant bone repair composition including a biocompatible or bioactive bone repair material and a mixture of non-random poly(oxyalkylene) block copolymers are described.
    Type: Application
    Filed: October 13, 2014
    Publication date: January 29, 2015
    Inventors: Gregory J. Pomrink, Cecilia A. Cao, Zehra Tosun, David M. Gaisser
  • Publication number: 20150024009
    Abstract: The invention provides an isolated genetically modified non-mammalian organism, wherein the activity of acyl-CoA:sterol acyltransferase/sterol O-acyltransferase (EC 2.3.1.26) and/or diacylglycerol acyltransferase/diacylglycerol O-acyltranferase (EC 2.3.1.20) and/or lecithin cholesterol acyl transferase/phospholipid: diacylglycerol acyltransferase (EC 2.3.1.158) and/or acyl CoA-wax alcohol acyltransferase (EC 2.3.1.75) is reduced or abolished in comparison with a corresponding wildtype organism, methods of use of such an organism, shuttle vehicles for making such an organism and methods for producing such an organism.
    Type: Application
    Filed: September 19, 2014
    Publication date: January 22, 2015
    Applicant: ORGANOBALANCE GMBH
    Inventors: Christine Lang, Andreas Raab
  • Publication number: 20150018435
    Abstract: The present invention includes a solid fat composition that includes an oil having saturated fat and a microbial oil having a long chain polyunsaturated fatty acid and an emulsifier. In particular, the solid fat composition can have high levels of long chain polyunsaturated fatty acid and low amounts of emulsifiers. In preferred embodiments, the polyunsaturated oil is an unwinterized microbial oil. The invention also relates to methods for making such compositions and food, nutritional, and pharmaceutical products comprising said compositions. The present invention also includes a microbial oil product prepared by extracting an oil-containing fraction comprising at least one LC-PUFA from a microbial biomass, and treating the fraction by a process of vacuum evaporation, wherein the oil product has not been subject to one or more of a solvent winterization step, a caustic refining process, a chill filtration process, or a bleaching process.
    Type: Application
    Filed: September 24, 2014
    Publication date: January 15, 2015
    Inventors: Jaouad FICHTALI, Neil Francis LEININGER, Jesus Ruben ABRIL, Naseer AHMED, S. P. Janaka Namal SENANAYAKE
  • Publication number: 20150017106
    Abstract: The present invention provides an agent for enhancing aroma intensity and/or aroma quality of a flavor composition to be added to a food, drink, pharmaceutical product, oral care product, or the like, the agent comprising ?-aminobutyric acid and naringenin, as well as a method for enhancing aroma intensity and/or aroma quality of the flavor composition.
    Type: Application
    Filed: February 15, 2013
    Publication date: January 15, 2015
    Applicant: TAKASAGO INTERNATIONAL CORPORATION
    Inventors: Yoshikazu Toyohara, Tadahiro Hiramoto, Naoto Omotani
  • Publication number: 20150017110
    Abstract: The present invention describes, in one aspect, the use of two oppositely charged surfactants as the primary emulsifiers in two separated parts of a product. The emulsifiers are chosen such that when the two parts of the emulsion product are mixed, the emulsifiers react to form water insoluble compounds that are no longer able to function as emulsifiers, thus, the oil phase of the emulsion is precipitated onto the skin along with the emulsifier reaction product. Since none of the deposited materials are water soluble, or capable of functioning as emulsifiers, the deposited oil phase is extremely resistant to being washed off. This technology finds applications in hand and body creams and lotions, baby care products, sunscreens, skin protective products, makeup systems, and automotive and furniture polishes.
    Type: Application
    Filed: October 2, 2014
    Publication date: January 15, 2015
    Inventor: John C. Carson
  • Patent number: 8933131
    Abstract: Disclosed herein are novel mixtures of scattered-branched chain fatty acids and derivatives of scattered-branched chain fatty acids. Further disclosed are uses of these mixtures in cleaning compositions (e.g., dishcare, laundry, hard surface cleaners) and/or personal care compositions (e.g., skin cleansers, shampoo, hair conditioners).
    Type: Grant
    Filed: January 11, 2011
    Date of Patent: January 13, 2015
    Assignee: The Procter & Gamble Company
    Inventors: Thomas Walter Federle, Jeffrey John Scheibel, Zaiyou Liu, Phillip Kyle Vinson, Howard David Hutton, III, John David Carter, Charles Winston Saunders, Jun Xu, Phillip Richard Green
  • Patent number: 8921430
    Abstract: The invention is directed to a mixture of esters according to the general formula (I), R1—C(?O)—O—R2, wherein R1 is an alkyl moiety with 7 to 9 carbon atoms and wherein R2 is a an alkyl moiety with 8 to 10 carbon atoms, wherein the mixture comprises 5 to 60 weight-% of ester of the general formula (I), wherein R1 is an alkyl moiety with 9 carbon atoms, based on the total amount of esters according to formula (I) and/or wherein the mixture comprises 5 to 60 weight-% of ester of the general formula (I), wherein R2 is an alkyl moiety with 10 carbon atoms, based on the total amount of esters according to formula (I). The invention is further directed to cosmetic and/or pharmaceutical compositions comprising such esters and processes for the production of such esters.
    Type: Grant
    Filed: June 19, 2010
    Date of Patent: December 30, 2014
    Assignee: Cognis IP Management GmbH
    Inventors: Rolf Kawa, Stefan Brüning
  • Publication number: 20140371332
    Abstract: Provided is a method for producing a vesicle composition having an aqueous phase as a continuous phase, containing: an oil phase-preparation step for dissolving an oil phase containing components (A) to (D) at a temperature of equal to or higher than melting point of the oil phase, the components (A) to (D) being: the component (A): a fatty acid of total carbon number of from 12 to 40; the component (B): a tertiary amine compound of total carbon number of from 8 to 75; the component (C): an organic acid of total carbon number of from 1 to 10; and the component (D): the first polyol, an emulsification step for adding the aqueous phase to the oil phase obtained in the oil phase-preparation step while being mixed; an addition step for adding a component (D?): the second polyol, after a quantity of the aqueous phase added to the oil phase is equal to or larger than 1 time by mass of a quantity of the oil phase; and cooling step for cooling the obtained composition after the emulsification step.
    Type: Application
    Filed: February 13, 2013
    Publication date: December 18, 2014
    Inventors: Kenko Fujii, Tsukasa Miyatani, Kensuke Aoyagi
  • Publication number: 20140356309
    Abstract: The present invention relates to a use of an acid in a manufacture of an organopolysiloxane through a condensation reaction of a silicon-containing compound containing a silicon-bonded hydroxyl group and a silicon-containing compound containing a silicon-bonded aminoxy group. Particularly, the present invention relates to a low-odor composition including such an organopolysiloxane. The composition according to the present invention can have little odor caused by a by-product produced via the condensation reaction described above.
    Type: Application
    Filed: December 4, 2012
    Publication date: December 4, 2014
    Inventors: Masaru Ozaki, Seiji Hori, Takatoshi Toyama, Kazuhiko Kojima, Tsunehito Sugiura
  • Publication number: 20140350128
    Abstract: Provided is a compound capable of gelling various aqueous compositions containing salt, acid and the like. A basic amino acid derivative represented by the formula (1): wherein each substituent is as defined in DESCRIPTION, or a salt thereof.
    Type: Application
    Filed: August 6, 2014
    Publication date: November 27, 2014
    Applicant: AJINOMOTO CO., INC.
    Inventors: Kenji HANABUSA, Masahiro SUZUKI, Takanori SUGIMOTO
  • Publication number: 20140341981
    Abstract: Disclosed are methods of preparing stable O/W emulsions by silicic acid complexation of micron-sized oil droplets, and stable emulsions prepared by silicic acid complexation. Compositions and products comprising the emulsions are also disclosed. Emulsions may be stable over an extended period of time at room temperature.
    Type: Application
    Filed: May 17, 2013
    Publication date: November 20, 2014
    Inventors: Vance BERGERON, Jean-Thierry SIMONNET, Florence LEVY, Aurélie LAFUMA, Stephane SANTUCCI
  • Patent number: 8889189
    Abstract: There are described solid compositions or examining drug solubility comprising bile salts and phospholipids, optionally containing buffer components suitable for preparation of intestinal media that simulate the composition of the intestinal fluids in fasted and fed states.
    Type: Grant
    Filed: October 16, 2012
    Date of Patent: November 18, 2014
    Assignee: Phares Pharmaceutical Research, N.V.
    Inventors: Steve Leigh, Mathew Louis Steven Leigh, Peter Van Hoogevest, Daniel Streich, Jacques Quinton
  • Publication number: 20140335034
    Abstract: A consumer product comprises silane-modified oil comprising a hydrocarbon chain selected from the group consisting of: a saturated oil, an unsaturated oil, and mixtures thereof; and at least one hydrolysable silyl group covalently bonded to the hydrocarbon chain. The consumer product further comprises a preservative.
    Type: Application
    Filed: May 8, 2014
    Publication date: November 13, 2014
    Applicant: The Procter & Gamble Company
    Inventors: Rajan Keshav PANANDIKER, Beth Ann SCHUBERT, John August WOS, Luke Andrew ZANNONI, Nathan Ray Whitely
  • Patent number: 8883221
    Abstract: Micronutrient combination product, wherein the micronutrient combination product comprises zeaxanthin, lutein, zinc and copper.
    Type: Grant
    Filed: December 17, 2004
    Date of Patent: November 11, 2014
    Assignee: Bausch & Lomb Incorporated
    Inventors: Guenter Bellmann, Gudrun Claus-Herz
  • Patent number: 8883204
    Abstract: The present invention relates to co-extruded pharmaceutical compositions and dosage forms including an active agent, such as an opioid agonist, and an adverse agent, such as an opioid antagonist. Such compositions and dosage forms are useful for preventing or discouraging tampering, abuse, misuse or diversion of a dosage form containing an active pharmaceutical agent, such as an opioid. The present invention also relates to methods of treating a patient with such a dosage form, as well as kits containing such a dosage form with instructions for using the dosage form to treat a patient.
    Type: Grant
    Filed: September 23, 2008
    Date of Patent: November 11, 2014
    Assignee: Purdue Pharma L.P.
    Inventors: Robert P. Flath, John K. Masselink
  • Patent number: 8883863
    Abstract: A pharmaceutical drug product with at least one drug substance capable of providing immediate release or modified release profiles. The drug substance is selected from an amorphous form with an active pharmaceutical ingredient and a first organic counterion wherein the amorphous form has a phase transition temperature of at least 100° C.; and a morphological form with the active pharmaceutical ingredient and a second organic counterion wherein the morphological form of the drug substance has a phase transition temperature of at least 100° C.
    Type: Grant
    Filed: December 21, 2012
    Date of Patent: November 11, 2014
    Assignee: Pisgah Laboratories, Inc.
    Inventors: Clifford Riley King, David William Bristol, Michael L. English
  • Publication number: 20140329916
    Abstract: Provided herein is a non-naturally occurring microbial organism having a methanol metabolic pathway that can enhance the availability of reducing equivalents in the presence of methanol. Such reducing equivalents can be used to increase the product yield of organic compounds produced by the microbial organism, such as adipate, 6-aminocaproate, hexamethylenediamine or caprolactam. Also provided herein are methods for using such an organism to produce adipate, 6-aminocaproate, hexamethylenediamine or caprolactam.
    Type: Application
    Filed: December 16, 2013
    Publication date: November 6, 2014
    Applicant: Genomatica, Inc.
    Inventors: Anthony P. Burgard, Robin E. Osterhout, Stephen J. Van Dien, Cara Ann Tracewell, Priti Pharkya, Stefan Andrae
  • Patent number: 8877240
    Abstract: Provided are tablet binding compositions for binding cleaning and/or disinfecting formulation components into tablets. The tablet binding compositions are suitable replacements for traditional tablet binder compounds, such as boric acid or zeolites. The tablet binding compositions provided herein can produce tablets of increased hardness at lower compression forces and, when dissolved, yield solutions of increased clarity compared to some traditional binder compounds. Also provided are processes for preparing the tablet binding compositions and methods for formation of tablets containing the tablet binding compositions.
    Type: Grant
    Filed: January 9, 2014
    Date of Patent: November 4, 2014
    Assignee: ChemLink Laboratories, LLC
    Inventor: Ryan Giffin Moore
  • Patent number: 8865779
    Abstract: The present invention provides edible compositions comprising a compound of the present invention, food products comprising such edible compositions and methods of preparing such food products. The present invention also provides methods of reducing the amount of NaCl in a food product, methods of reducing the sodium intake in a diet, and methods of reducing bitter taste in a food product.
    Type: Grant
    Filed: April 15, 2011
    Date of Patent: October 21, 2014
    Assignees: Chromocell Corporation, Kraft Foods Group Brands LLC
    Inventors: Kambiz Shekdar, Daniel Lavery, Joseph Gunnet, Jessica Langer, Jane V. Leland, David Hayashi, Peter H. Brown, Louise Slade, William P. Jones
  • Publication number: 20140271596
    Abstract: The present invention relates to an emulsified hydrogel composition and to a production method therefor, wherein, by incorporating between 20 and 30 percent by weight of a gelling solution and an emulsion obtained by mixing between 45 and 60 percent by weight of an aqueous component and between 15 and 30 percent by weight of an oil component, it is possible to simultaneously provide the skin with an aqueous fraction and an oil fraction, and it is possible to enhance functionality due to the inclusion of a high content of a dermatologically active component dissolved in the oil component.
    Type: Application
    Filed: September 12, 2012
    Publication date: September 18, 2014
    Applicant: GENIC CO., LTD.
    Inventors: Sung Jang Kim, Hyong-ii Park, Jae Han Cho, Eun Kyoung Choi, Jae hoon Kwak, Jae Min Lim, Hyun Jun Lim, Jai Hyun Kim, Min Seok Kim, Jin A. Yang, Hyun Oh Yoo, Jong Chul Kim
  • Publication number: 20140256833
    Abstract: This invention relates to a composition that is mild to the skin containing a cosmetically acceptable oil; water; a cosmetically acceptable emulsifier having an HLB of from about 1 to about 25; and a preservative comprising an organic acid selected from the group consisting of benzoic acid, p-anisic acid, sorbic acid, lactic acid, acetic acid, formic acid, oxalic acid, tartaric acid, salicylic acid and citric acid; wherein said composition has a pH less than 5 and a buffer capacity of between about 0.001 and about 0.039.
    Type: Application
    Filed: April 29, 2014
    Publication date: September 11, 2014
    Applicant: Johnson & Johnson Consumer Companies, Inc.
    Inventors: Euen T. Gunn, Patricia Bonner, Delores Santora
  • Patent number: 8828960
    Abstract: The invention relates to pharmaceutical compositions that provide sustained-release of a pharmaceutically active compound and to methods of treating or preventing a condition in an animal by administering the pharmaceutical compositions to the animal. When the pharmaceutical compositions are administered to an animal by injection, they form a drug depot that releases the pharmaceutically active compound over time. The pharmaceutical compositions can also be administered orally.
    Type: Grant
    Filed: July 11, 2008
    Date of Patent: September 9, 2014
    Assignee: IDEXX Laboratories, Inc.
    Inventors: Yerramilli V.S.N. Murthy, Michael Atkinson
  • Publication number: 20140248410
    Abstract: A carotenoid-containing composition including: a carotenoid component containing a crystalline carotenoid that is in an amorphous state; a (poly)glycerol fatty acid ester that contains from one to six glycerol units and from one to six fatty acid units and has at least one hydroxyl group resulting from a glycerol unit; a fatty acid ester component which is at least one selected from the group consisting of triesters of glycerol and fatty acids, and esters of alcohols having one hydroxyl group and fatty acids, contains no hydroxyl group in a molecule, and has from 10 to 60 carbon atoms in total; and an antioxidant.
    Type: Application
    Filed: May 15, 2014
    Publication date: September 4, 2014
    Applicant: FUJIFILM CORPORATION
    Inventor: Hiroyuki KITAOKA
  • Publication number: 20140243430
    Abstract: The present invention is embodied by a composition capable inducing weight loss in a patient in need thereof.
    Type: Application
    Filed: May 2, 2014
    Publication date: August 28, 2014
    Applicant: SDG, INC.
    Inventors: W. BLAIR GEHO, JOHN R. LAU
  • Publication number: 20140235733
    Abstract: The present invention relates to an improved process for the preparation of unsaturated fatty acids and to a process for the preparation of triglycerides with an increased content of unsaturated fatty acids. The invention relates to the generation of transgenic microorganism, with an increased content of fatty acids, oils or lipids with ?6 double bonds owing to the expression of a moss ?6-desaturase. The invention furthermore relates to transgenic organisms comprising a ?6-desaturase gene, and to the use of unsaturated fatty acids ort of the triglycerides with an increased content if unsaturated fatty acids prepared in the process.
    Type: Application
    Filed: May 2, 2014
    Publication date: August 21, 2014
    Applicant: BASF Plant Science GmbH
    Inventors: Ernst Heinz, Thomas Girke, Jodi Scheffler, Oswaldo Da Costa e Silva, Hermann Schmidt, Ulrich Zähringer, Ralf Reski
  • Patent number: 8802133
    Abstract: Disclosed is 1) a method for greatly increasing the solubility of useful actives in siloxane matrix-forming preparations, and 2) the associated preparations, themselves. Volatilizing coagents are utilized to give novel gels containing heretofore siloxane-insoluble additives.
    Type: Grant
    Filed: July 13, 2012
    Date of Patent: August 12, 2014
    Assignee: Advanced Bio-Technologies, Inc.
    Inventor: Paul Guilbaud
  • Publication number: 20140219930
    Abstract: The following invention relates to a taste enhancer and a method of enhancing taste. The invention relates the use of a cooling enhancing composition which provides cooling enhancement when combined with other cooling compounds.
    Type: Application
    Filed: December 21, 2012
    Publication date: August 7, 2014
    Applicant: International Flavors & Fragrances Inc.
    Inventors: Thumpalasseril V. John, Mark L. Dewis, Kathryn Bardsley, Kenneth J. Kraut, Hou Wu