Higher Fatty Acid Or Derivative Containing Patents (Class 514/943)
  • Patent number: 8889189
    Abstract: There are described solid compositions or examining drug solubility comprising bile salts and phospholipids, optionally containing buffer components suitable for preparation of intestinal media that simulate the composition of the intestinal fluids in fasted and fed states.
    Type: Grant
    Filed: October 16, 2012
    Date of Patent: November 18, 2014
    Assignee: Phares Pharmaceutical Research, N.V.
    Inventors: Steve Leigh, Mathew Louis Steven Leigh, Peter Van Hoogevest, Daniel Streich, Jacques Quinton
  • Patent number: 8877729
    Abstract: This disclosure provides a range of amino acid lipid compounds and compositions useful for drug delivery, therapeutics, and the diagnosis and treatment of diseases and conditions. The amino acid lipid compounds and compositions can be used for delivery of various agents such as nucleic acid therapeutics to cells, tissues, organs, and subjects.
    Type: Grant
    Filed: July 1, 2013
    Date of Patent: November 4, 2014
    Assignee: Marina Biotech, Inc.
    Inventors: Steven C. Quay, Michael E. Houston, Jr., Pierrot Harvie, Roger C. Adami, Renata Fam, Mary G. Prieve, Kathy L. Fosnaugh, Shaguna Seth
  • Patent number: 8834919
    Abstract: The present invention provides lipid emulsions and methods of intravenously administering lipid emulsions to treat systemic toxicity caused by foreign lipophilic and amphiphilic substances. In particular, methods are provided to treat cardiovascular impairment, such as cardiotoxicity, asystole and ischemia of the brain and heart, and neurological impairments, such as seizures and comas, caused by foreign lipophilic and amphiphilic substances, including cardiovascular impairment caused by local anesthetics, tricyclic antidepressants, sodium channel blockers, and calcium channel blockers.
    Type: Grant
    Filed: July 25, 2007
    Date of Patent: September 16, 2014
    Inventors: Guy Weinberg, Paul Hertz
  • Patent number: 8697172
    Abstract: The present invention relates a new drink formula comprising fresh marine omega-3 oil in an emulsion and antioxidants well known to be health promoting to humans, and process for the production of said drink and the use of said drink for production of a medicament.
    Type: Grant
    Filed: March 26, 2009
    Date of Patent: April 15, 2014
    Assignee: Smartfish AS
    Inventors: Janne Sande Mathisen, Henrik Mathisen
  • Patent number: 8628626
    Abstract: A heavy oil cleaning composition comprising: a) a blend of dibasic esters comprising dialkyl methylglutarate and at least one of a dialkyl adipate or dialkyl ethylsuccinate; b) at least one terpene; and c) at least one surfactant. Also described are methods for delivering a solvent at reduced concentration comprising the steps of: a) obtaining a terpene-based solvent; and b) mixing the terpene-based solvent with a carrier fluid (the carrier fluid comprising a microemulsion of i) a blend of dibasic esters selected from the group consisting of dialkyl methylglutarate, dialkyl adipate, dialkyl ethylsuccinate, dialkyl succinate, dialkyl glutarate and any combination thereof, ii) at least one surfactant selected from the group consisting of a terpene alkoxylate, an alcohol alkoxylate and any combination thereof; and iii) water) in order to obtain a mixture to clean heavy oils.
    Type: Grant
    Filed: December 8, 2011
    Date of Patent: January 14, 2014
    Assignee: Rhodia Operations
    Inventors: David Fluck, Amit Sehgal, Satyen Trivedi, Ruela Talingting Pabalan, Charles Aymes
  • Patent number: 8609629
    Abstract: The present invention relates to methods of co-administration of various vitamin and mineral compositions, and in a specific embodiment, said methods comprise co-administering one composition comprising vitamin A, beta carotene, B-complex vitamins, vitamin C, vitamin D3, vitamin E, iron, magnesium and zinc, and a second composition comprising omega-3 fatty acids such as DHA, to supplement the nutritional needs of individuals within physiologically stressful states; and kits provided for co-administration of various vitamin and mineral compositions, and in a specific embodiment, said kits comprise one composition comprising vitamin A, beta carotene, B-complex vitamins, vitamin C, vitamin D3, vitamin E, iron, magnesium and zinc, and a second composition comprising omega-3 fatty acids such as DHA, to supplement the nutritional needs of individuals within physiologically stressful states.
    Type: Grant
    Filed: January 23, 2012
    Date of Patent: December 17, 2013
    Assignee: Evertt Laboratories, Inc.
    Inventors: John A. Giordano, Charles J. Balzer
  • Patent number: 8569218
    Abstract: A gelled cleaning composition is provided that includes a standard temperature and pressure (STP) liquid oil or STP malleable wax present from 0.1 to 9.9 total weight percent. An emulsifier is present from 0.01 to 10 total weight percent, along with an alkylene glycol present from 0.002 to 11 total weight percent. A microemulsion is present in the composition from 0.2 to 15 total weight percent. Water forms a majority of the composition such that the composition is monophasic for at least 4 months storage at 20° Celsius. The composition is well suited for use in a process to remove a lipophilic substance from hands or an inanimate substrate by applying the composition and after allow sufficient time for the substance to be softened or solubilized, removing the composition and at least a portion of the substance. Silicone gaskets, as well as other cured resins and paints are readily removed.
    Type: Grant
    Filed: January 18, 2012
    Date of Patent: October 29, 2013
    Assignee: Illinois Tool Works, Inc.
    Inventor: Claudia E. Britton
  • Patent number: 8491920
    Abstract: The invention relates to a silicone-free skin protection composition, in particular a composition to protect against cold, containing the components a.) at least one oil with a pour point in accordance with DIN ISO 30 16 of ??10° C., b.) at least one polyol c.) at least one emulsifier d.) optionally at least one wax, where the viscosity difference in the temperature interval from +4° C. to +50° C. of highest and lowest viscosity of the skin protection composition has a value in the range from 0 to ?20 000 mPas.
    Type: Grant
    Filed: June 12, 2012
    Date of Patent: July 23, 2013
    Assignee: Evonik Degussa GmbH
    Inventors: Marcel Veeger, Petra Allef
  • Patent number: 8287846
    Abstract: The present invention relates to odour improved dermatological or cosmetic preparations comprising N-acetylcysteine and a polyol system containing one or more polyols as masking odour agents. The emulsions of the present invention are useful in the treatment of dermatological disorders or cosmetic skin conditions.
    Type: Grant
    Filed: July 13, 2007
    Date of Patent: October 16, 2012
    Assignee: ZAMBON S.p.A.
    Inventors: Luca Rampoldi, Alberto Moretto, Alessandro Grassano
  • Patent number: 8287907
    Abstract: There are described solid compositions or examining drug solubility comprising bile salts and phospholipids, optionally containing buffer components suitable for preparation of intestinal media that simulate the composition of the intestinal fluids in fasted and fed states.
    Type: Grant
    Filed: November 10, 2006
    Date of Patent: October 16, 2012
    Assignee: Phares Pharmaceutical Research, N.V.
    Inventors: Steve Leigh, Matthew Louis Steven Leigh, Peter Van Hoogevest, Daniel Streich, Jacques Quinton
  • Patent number: 8252847
    Abstract: The invention relates to a silicone-free skin protection composition, in particular a composition to protect against cold, containing the components a.) at least one oil with a pour point in accordance with DIN ISO 30 16 of ??10° C., b.) at least one polyol c.) at least one emulsifier d.) optionally at least one wax, where the viscosity difference in the temperature interval from +4° C. to +50° C. of highest and lowest viscosity of the skin protection composition has a value in the range from 0 to ?20 000 mPas.
    Type: Grant
    Filed: November 9, 2007
    Date of Patent: August 28, 2012
    Assignee: Evonik Stockhausen GmbH
    Inventors: Marcel Veeger, Petra Allef
  • Patent number: 8211948
    Abstract: The present invention relates to a lyophilized nanoemulsion comprising a lipophilic phase and one or more sucrose fatty acid esters, to the nanoemulsion which can be prepared from the lyophilized nanoemulsion by redispersion, and to a process for the preparation of the lyophilized nanoemulsion.
    Type: Grant
    Filed: February 26, 2009
    Date of Patent: July 3, 2012
    Assignee: Merck Patent GmbH
    Inventors: Andrea Hanefeld, Martina Schmidt, Simon Geissler, Peter Langguth
  • Patent number: 8178584
    Abstract: The present invention relates to a water-in-oil emulsified composition containing a sphingosine represented by the following formula (1): (R1 represents a hydrocarbon group optionally having a substituent; Y represents methylene, methine or O; X1, X2 and X3 each represent H, OH or acetoxy group; X4 represents H, acetyl group or the like; R2, R3 each represents H, OH or the like; R represents H, amidino group or the like; and a stands for 2 or 3), (B) a C6-30 fatty acid, and (C) an oil component. This water-in-oil emulsified composition has excellent stability and provides a good feeling to skin upon use.
    Type: Grant
    Filed: June 9, 2004
    Date of Patent: May 15, 2012
    Assignee: Kao Corporation
    Inventors: Koji Okubo, Yumiko Yamamoto
  • Patent number: 8101587
    Abstract: The present invention relates to methods of co-administration of various vitamin and mineral compositions, and in a specific embodiment, said methods comprise co-administering one composition comprising vitamin A, beta carotene, B-complex vitamins, vitamin C, vitamin D3, vitamin E, iron, magnesium and zinc, and a second composition comprising omega-3 fatty acids such as DHA, to supplement the nutritional needs of individuals within physiologically stressful states; and kits provided for co-administration of various vitamin and mineral compositions, and in a specific embodiment, said kits comprise one composition comprising vitamin A, beta carotene, B-complex vitamins, vitamin C, vitamin D3, vitamin E, iron, magnesium and zinc, and a second composition comprising omega-3 fatty acids such as DHA, to supplement the nutritional needs of individuals within physiologically stressful states.
    Type: Grant
    Filed: April 10, 2009
    Date of Patent: January 24, 2012
    Assignee: Everett Laboratories, Inc.
    Inventors: John A. Giordano, Charles J. Balzer
  • Patent number: 7964201
    Abstract: A concentrate including, by weight (a) 10% to 60%, preferably 25% to 35%, of a saturated fatty acid selected from stearic or palmitic acid, or mixtures thereof, in an adduct of an amidopropyldimethyl-2-hydroxyethyl ammonium halide, with substantially no free acid present, and (b) 40% to 90%, preferably 65% to 75%, of a low molecular weight alcohol or saturated fatty alcohol or alcohols, for use in personal care products, including hair care and skin care compositions.
    Type: Grant
    Filed: May 12, 2005
    Date of Patent: June 21, 2011
    Assignee: ISP Investments Inc.
    Inventors: Steven H. Bertz, Ilya Makarovsky
  • Patent number: 7939505
    Abstract: This disclosure provides a range of amino acid lipid compounds and compositions useful for drug delivery, therapeutics, and the diagnosis and treatment of diseases and conditions. The amino acid lipid compounds and compositions can be used for delivery of various agents such as nucleic acid therapeutics to cells, tissues, organs, and subjects.
    Type: Grant
    Filed: May 2, 2008
    Date of Patent: May 10, 2011
    Assignee: Marina Biotech, Inc.
    Inventors: Steven C. Quay, Michael Houston, Jr., Pierrot Harvie, Roger C. Adami, Renata Fam, Mary Gallagher Prieve, Kathy Lynn Fosnaugh, Shaguna Seth
  • Patent number: 7754775
    Abstract: Topical cosmetic and pharmaceutical oil-in-water emulsions wherein an emulsifier blend, comprising a mixture of at least two sucrose esters in combination with at least one solid fatty alcohol, forms a multi-lamellar liquid crystalline network that effectively moisturizes and protects the skin, and provides a useful vehicle for delivery of active ingredients. Sucrose esters are used in emulsions of the present invention at very low concentrations (from about 0.2 % to about 1.2 % by combined weight of sucrose esters relative to the total weight of the emulsion).
    Type: Grant
    Filed: April 23, 2004
    Date of Patent: July 13, 2010
    Inventors: Michel F. Mercier, Paul Thau, John Chase
  • Patent number: 7416719
    Abstract: The present invention is a sunscreen composition that has at least one sunscreen agent and at least one glucoside emulsifier. The composition also has water. Preferably, the sunscreen composition also has at least one of the following additional components: an emulsifier other than glucoside, emollient, skin-feel additive, moisturizing agent, film former/waterproofing agent, pH adjuster/chelating agent, preservative, or any combinations thereof. The composition is a stable oil-in-water emulsion.
    Type: Grant
    Filed: April 30, 2004
    Date of Patent: August 26, 2008
    Assignee: Playtex Products, Inc.
    Inventors: Jose L. Huerta, James Sanogueira, Jennifer Fuller
  • Patent number: 7387790
    Abstract: Nanoparticles made from a select group of lipids and optionally containing a therapeutically active agent are employed in pharmaceutical compositions for delivery to targeted tissues and/or cells for the treatment or diagnosis of such diseases as cancer.
    Type: Grant
    Filed: June 14, 2002
    Date of Patent: June 17, 2008
    Assignee: Cornerstone Pharmaceuticals
    Inventors: Robert Shorr, Robert Rodriguez
  • Patent number: 7261903
    Abstract: Lipid emulsion compositions and methods of using such composition via intravenous infusion to reduce the bioavailability and toxicity of poisonous agents in the bloodstream.
    Type: Grant
    Filed: February 22, 1999
    Date of Patent: August 28, 2007
    Inventors: Guy Weinberg, Paul Hertz
  • Patent number: 7220428
    Abstract: Nanoparticles made from a select group of lipids and optionally containing a therapeutically active agent are employed in pharmaceutical compositions for delivery to targeted tissues and/or cells for the treatment or diagnosis of such diseases as cancer.
    Type: Grant
    Filed: October 27, 2004
    Date of Patent: May 22, 2007
    Assignee: Cornerstone Pharmaceuticals
    Inventors: Robert Shorr, Robert Rodriguez
  • Patent number: 7199151
    Abstract: The invention provides conjugates of cis-docosahexaenoic acid and pharmaceutical agents useful in treating noncentral nervous system conditions. Methods for selectively targeting pharmaceutical agents to desired tissues are provided.
    Type: Grant
    Filed: July 14, 2003
    Date of Patent: April 3, 2007
    Assignee: Luitpold Pharmaceuticals, Inc.
    Inventors: Victor E. Shashoua, Charles E. Swindell, Nigel L. Webb, Matthews O. Bradley
  • Patent number: 7169382
    Abstract: A reconstructed epidermis/skin equivalent supplemented with at least one ceramide 7 and/or 5.5 compound, suited for reinforcing the barrier function of normal human epidermis and for improving the barrier function of dry skin and of reconstructed skin or skin equivalents, is prepared by introducing the at least one ceramide 7 and/or 5.5 compound into the culture medium of such reconstructed epidermis/skin equivalent and/or topically applying onto the face surface of such reconstructed epidermis/skin equivalent a composition which comprises lipid lamellar vesicles incorporating at least one ceramide 7 and/or 5.5 compound.
    Type: Grant
    Filed: January 29, 2004
    Date of Patent: January 30, 2007
    Assignee: L'Oreal
    Inventors: Mélanie Chopart, Isabelle Castiel, Jean-Thierry Simonnet
  • Patent number: 7094395
    Abstract: A method for producing a colored cosmetic composition having inorganic pigments resistant to agglomeration in an oil-in-water emulsion. The method includes the following: preparing an oil dispersion by adding inorganic pigments directly to an oil; preparing an aqueous base that includes water; combining the oil dispersion and aqueous base; and partitioning the inorganic pigments between the oil and the aqueous phase under controlled conditions, for example, hydrophile-lipophile balance, agitation time and speed, and cooling rate. The present invention provides a process to easily disperse iron-oxide pigments, even black iron-oxide pigments, in oil-in-water emulsions. The present invention provides colored cosmetic compositions that have excellent properties, such as smoothness, adhesion to skin, uniform color, ease of removal, smudge resistance and non-oiliness.
    Type: Grant
    Filed: April 25, 2002
    Date of Patent: August 22, 2006
    Assignee: Access Business Group International LLC
    Inventors: Di Qu, Jesse C. Leverett
  • Patent number: 7029656
    Abstract: Formulations, methods and devices for producing formulations and methods for nebulizer delivery of formulations of water-insoluble drugs are provided. Also provided are methods for minimizing wastage of drugs administered by nebulizer, and for the achievement of quantitative dosing with diluent from a mass marketed formulations, which because of the mass market is much less costly per dose than formulations manufactured specifically for much lower volume medical use.
    Type: Grant
    Filed: December 15, 2000
    Date of Patent: April 18, 2006
    Inventor: Robert E. Coifman
  • Patent number: 6984691
    Abstract: A W/O/W type composite emulsion, wherein a W/O type emulsion containing water, an oil ingredient and a lipophilic emulsifier each in a proportion expressed in term of mass ratio falling within a range enclosed with bold lines in FIG. 1 is dispersed in an external aqueous phase with a water-soluble macromolecule blended therein has a sufficient stability, and permits preserving a percent inclusion of medical substances included in an internal aqueous phase of the W/O/W type composite emulsion at a high level. Because of the characteristics, it is now possible to blend in a liquid formulation medical substances having an unfavorable taste or unstable medical substances which have to date hardly been included in liquid formulations with low viscosity, so that the W/O/W type composite emulsion can be utilized for liquid formulations including a liquid formulation for internal application, injections, etc.
    Type: Grant
    Filed: November 29, 2001
    Date of Patent: January 10, 2006
    Assignee: Taisho Pharmaceutical Co., Ltd.
    Inventors: Tohru Nagahama, Tomoaki Yoshino
  • Patent number: 6958157
    Abstract: The invention relates to a new conjugate, based on triiodomethane, which also contains at least one natural organic and/or modified natural organic and/or inorganic thickener. Cellulose ethers or starch ethers are particularly suitable for use as the thickener. Said conjugate can be used as a disinfectant and can be introduced into ointments or creams. As a hydrogel containing water and a solvent in addition to the conjugate, with a viscosity of between 5,000 and 400,000 mPa*s (20° C.), preferably between 10,000 and 30,000 wPa*s (20° C.), the product is extremely suitable for use as a disinfectant cleaner and hygiene product for cleaning and maintaining animal horn for example of horses, cattle and sheep. In addition, the hydrogel can contain at least one polyalcohol, in particular glycerine. According to one production method, a hydrogel is produced from water and a thickener and the polyalcohol is fast added thereto at a temperature of between 20 and 60° C.
    Type: Grant
    Filed: November 25, 2000
    Date of Patent: October 25, 2005
    Inventor: Ulrich Doht
  • Patent number: 6955818
    Abstract: A non-irritant topically acceptable carrier selected from the group consisting of: a) i) at least one of tripropylene glycol methyl ether and dipropylene glycol methyl ether, and ii) at least one of alcohol, wool grease and propylene glycol, wherein (i) is present in an amount of at least about 60% wt of the carrier; b) i) at least one of octyl palmitate, octyl stearate and glyceryl tri caprylate/caprate, and ii) at least one of dioctyl succinate, isopropyl myristate, cetearyl octanoate, propylene glycol 2 myristyl ether propionate, isopropyl palmitate, isopropyl laurate, isocetyl stearate, oleic acid and methyl oleate, and optionally including iii) at least one of alcohol, wool grease and propylene glycol, wherein (ii) is present in an amount of up to about 40% wt of the carrier; and c) i) at least one of octyl palmitate, octyl stearate and glyceryl tri caprylate/caprate, and ii) at least one of alcohol, wool grease and propylene glycol, wherein (i) is present in an amount of at least about 60% wt of the car
    Type: Grant
    Filed: November 17, 2000
    Date of Patent: October 18, 2005
    Assignee: Eli Lilly and Company
    Inventors: Kristina Clare Hacket, Lionel Barry Low, James Terence Rothwell
  • Patent number: 6946426
    Abstract: Provided is a method of formulating hydrophobic pesticides comprising emulsifying an aqueous phase and a water-immiscible phase to form a formulation; wherein the aqueous phase is comprised of water and optionally a freeze/thaw agent, one or more emulsifiers, or combinations thereof, and the water-immiscible phase comprises the hydrophobic pesticide and one or more emulsifiers.
    Type: Grant
    Filed: March 21, 2001
    Date of Patent: September 20, 2005
    Assignee: FMC Corporation
    Inventors: Timothy M. Martin, MaryEllen Lavin
  • Patent number: 6896897
    Abstract: A flexible applicator for applying an oil-in-water emulsion comprises: (1) an allantoin-containing oil-in-water emulsion; and (2) a flexible element that adsorbs or absorbs the emulsion such that the emulsion is applied to the skin of a patient on whom the flexible applicator is placed. The allantoin-containing emulsion, containing allantoin and an emulsifier, has improved stability coming from the adjustment of the pH to a range of 3.0 to 6.0; preferably, the pH is in the range of 4.5 to about 5.8. The lower pH preserves the stability of the allantoin and the functionality of the emulsifier system is maintained. The emulsifier system can be a nonionic emulsifier or an anionic emulsifier plus beeswax. The acid used to adjust the pH can be an organic acid or an inorganic acid. The emulsion can further comprise other ingredients such as herbal extracts, chelating agents, preservatives, emollients, solvents, and fragrance.
    Type: Grant
    Filed: August 27, 2001
    Date of Patent: May 24, 2005
    Assignee: Alwyn Company, Inc.
    Inventor: Elliott Farber
  • Patent number: 6864274
    Abstract: An allantoin-containing skin cream composition can comprise allantoin and at least one anionic or nonionic emulsifier that is substantially hydrophilic and is soluble in water. The pH of the composition is in a range of from about 3.0 to about 6.0; preferably, the pH of the composition is from about 5.0 to about 6.0. The composition can further comprise an acidic anionic polymer. A preferred acidic anionic polymer is a carboxypolymethylene polymer. The composition can further comprise a carbohydrate polymer such as galactoarabinan, polygalactose or polyarabinose. The composition can additionally comprise other ingredients such as herbal extracts, an antioxidant component, an emollient component, a chelator, a solvent component, or a preservative component. The composition is useful as a skin protectant.
    Type: Grant
    Filed: January 11, 2001
    Date of Patent: March 8, 2005
    Assignee: Alwyn Company, Inc.
    Inventor: Elliott Farber
  • Patent number: 6855327
    Abstract: Free-flowing granular dispersing agents for use in water-dispersible granule (WDG) agricultural chemical formulations are a composite substance comprised of an alkyl polyglycoside and a polymeric anionic dispersant. The granular composite dispersing agents can be used in granular or liquid agricultural chemical formulations, exhibit outstanding attrition resistance, excellent dispersional stability after accelerated aging and low moisture content when made into a paste. The composite dispersing agents are useful as primary dispersants in dry agricultural formulations (wettable powders and water-dispersible granules) and in aqueous suspension concentrates.
    Type: Grant
    Filed: June 16, 1999
    Date of Patent: February 15, 2005
    Assignee: Cognis Corporation
    Inventor: Alan P. Lundstedt
  • Patent number: 6830746
    Abstract: The present invention is a sunscreen composition that has at least one sunscreen agent and at least one glucoside emulsifier. The composition also has water. Preferably, the sunscreen composition also has at least one of the following additional components: emulsifier other than glucoside, emollient, skin-feel additive, moisturizing agent, film former/waterproofing agent, pH adjuster/chelating agent, preservative, or any combinations thereof. The composition is a stable oil-in-water emulsion.
    Type: Grant
    Filed: September 21, 2001
    Date of Patent: December 14, 2004
    Assignee: Playtex Products, Inc.
    Inventors: James SaNogueira, Jennifer Fuller
  • Patent number: 6821934
    Abstract: Water-in-oil emulsions (a) with a viscosity of at most 5000 mPa.
    Type: Grant
    Filed: December 14, 2000
    Date of Patent: November 23, 2004
    Assignee: Beiersdorf AG
    Inventors: Andreas Bleckmann, Rainer Kröpke, Günther Schneider
  • Patent number: 6777450
    Abstract: The invention relates to a water-thin emulsion comprising a non-phospholipid, non-ethoxylated pseudoemulsifier system, the system having a chemical composition with at least one hydrophobic moiety and at least one polar moiety, the size, shape and/or planar arrangement of the hydrophobic and polar moieties being asymmetrical with respect to each other. The emulsion of the invention is prepared by high-pressure homogenization of a crude oil and water emulsion containing the pseudoemulsifier. The emulsions require little or no traditional emulsifier to maintain stability, and are particularly useful in the preparation of multiple emulsions.
    Type: Grant
    Filed: May 26, 2000
    Date of Patent: August 17, 2004
    Assignee: Color Access, Inc.
    Inventors: Liliana George, Andrew J. Bevacqua, Gheorghe Cioca, Michelle Matathia, Charles Craig Tadlock
  • Patent number: 6703028
    Abstract: An aqueous or aqueous/alcoholic cosmetic composition which can be sprayed, comprising an aqueous dispersion of insoluble film-forming polymer particles and at least one insoluble silicone, wherein the polymer particles are present in a concentration greater than 15%, relative to the total weight of the composition, and further wherein the glass transition temperature of the insoluble polymer particles ranges from 15 to 35° C. The invention also relates to a process for the cosmetic treatment of keratinous substances using these compositions and to the use of the silicone for improving the quality of the spraying of the composition.
    Type: Grant
    Filed: October 13, 2000
    Date of Patent: March 9, 2004
    Assignee: L'Oreal, S.A.
    Inventors: Henri Samain, Daniel Bauer, Jean-Michel Sturla
  • Patent number: 6673826
    Abstract: An improved method of treating skin diseases comprises applying to the skin of a patient suffering such a skin disease an allantoin-containing composition in a therapeutically effective quantity. The allantoin-containing composition is a water-in-oil emulsion that includes allantoin and an emulsifier system that includes at least one emulsifier that is either an anionic emulsifier or a nonionic emulsifier. If the emulsifier is an anionic emulsifier, the emulsifier system can include beeswax. The nonionic emulsifiers used can include at least one nonionic emulsifier that is an ethoxylated ether or an ethoxylated ester whose carbon chain length ranges from 8 to 22 carbon atoms. Alternatively, the emulsifier system can include an acidic anionic polymer such as carboxypolymethylene and an anionic emulsifier. In another alternative, the emulsifier system can include the acidic anionic polymer and a nonionic emulsifier, or the acidic anionic polymer alone.
    Type: Grant
    Filed: January 11, 2001
    Date of Patent: January 6, 2004
    Assignee: Alwyn Company, Inc.
    Inventor: Elliott Farber
  • Patent number: 6667044
    Abstract: Microemulsion gels a) based on water in oil type microemulsions, comprising an oil phase which is essentially composed of not easily volatile components, an aqueous phase containing one or more polyethoxylated W/O emulsifiers and/or one or more polypropoxylated W/O emulsifiers and/or one or more polyethoxylated and polypropoxylated W/O emulsifiers and/or one or more monoesters, diesters, polyesters of polyols as W/O emulsifiers and/or one or more monoethers, diethers, polyethers of polyols as W/O emulsifiers and/or one or more dimethicone copolyols as W/O emulsifiers and/or one or more fatty alcohols or fatty acids as W/O emulsifiers and/or one or more sorbitan esters as W/O emulsifiers and/or one or more methyl glucose esters as W/O emulsifiers, and also comprising if desired one or more O/W emulsifiers, obtained in such a way that a mixture of basic components comprising an aqueous phase, an oil phase, one or more inventive emulsifiers is produced, being the HLB value of the emulsifier or emulsifier combina
    Type: Grant
    Filed: June 18, 1999
    Date of Patent: December 23, 2003
    Assignee: Beiersdorf AG
    Inventors: Khiet Hien Diec, Wolfgang Meier, Jörg Schreiber
  • Patent number: 6660278
    Abstract: A controlled release composition for a biologically active material, which composition is liquid or liquid crystalline and comprises at least one medium or long-chain fatty acid ester of diglycerol as a carrier for said biologically active material, said biologically active material being dissolved or dispersed in said carrier. Said composition is especially useful as a medical composition.
    Type: Grant
    Filed: July 8, 1999
    Date of Patent: December 9, 2003
    Assignee: GS Development AB
    Inventors: Kåre Larsson, Helena Ljusberg-Wahren, Niels Krog
  • Patent number: 6653288
    Abstract: Injectable compositions containing a liquid solvent free of solid polymers, anthelmintic agent(s)and hormonal growth promoter(s), where the anthelmintic agent(s) and the hormonal growth promoter(s) are dissolved in the polymer free solvent system. The present invention additionally relates to methods of promoting animal growth and inhibiting parasitic infection/infestation with these compositions, as well as methods of preparing such compositions.
    Type: Grant
    Filed: September 30, 2002
    Date of Patent: November 25, 2003
    Assignee: Virbac S.A.
    Inventors: Vincent Beuvry, Georges Bufala, Guy Derrieu
  • Patent number: 6649175
    Abstract: A skin barrier lotion for protection against contact with irritants comprises: about 5 to 15 percent by weight of a long-chain fatty acid; about 1 to 5 percent by weight of a long-chain fatty alcohol; about 1 to 10 percent by weight of a hydrocarbon oil; about 1 to 30 percent by weight of a silicone skin protectant; about 0.5 to about 5 percent by weight of an alkanolamine; about 0.5 to about 5 percent by weight of a humectant; about 0.5 to about 10 percent by weight of an inorganic skin protectant; about 0.5 to 15 weight percent of a preservative; and about 50 to 90 percent by weight water. Optionally, the lotion will also contain up to about 5 percent by weight of a fragrance, odor neutralizer or a mixture thereof.
    Type: Grant
    Filed: May 3, 1999
    Date of Patent: November 18, 2003
    Assignee: Schering-Plough HealthCare Products, Inc.
    Inventors: Joseph A. Haslwanter, William F. Rencher
  • Patent number: 6649577
    Abstract: Water-in-oil emulsions (a) with a viscosity of at most 5000 mPa·s (b) with a content of water and water-soluble substances totalling at least 75% by weight, and with a content of lipids, emulsifiers and lipophilic constituents totalling at most 15%, based in each case on the total weight of the preparations, (c) the oil phase of which comprises at least 75% of one or more substances chosen from the group of nonpolar lipids which are liquid at room temperature and have a polarity of greater than 30 mN/m, and/or silicones of any polarity this weight proportion being based on the total weight of the oil phase, (d) comprising at least one interface-active substance chosen from the group of substances of the general formula (I)
    Type: Grant
    Filed: December 11, 2000
    Date of Patent: November 18, 2003
    Assignee: Beiersdorf AG
    Inventors: Andreas Bleckmann, Rainer Kröpke, Günther Schneider
  • Patent number: 6645509
    Abstract: The present invention relates to a cosmetic or pharmaceutical composition comprising, in a physiologically acceptable medium, a purified natural or synthetic epidermis-specific polypeptide which is involved in horny layer cell cohesion. The invention also relates to a cosmetic or pharmaceutical composition comprising a mixture of polypeptides derived from the proteolysis of the purified polypeptide of the present invention. The present invention further relates to a method for strengthening horny layer cell cohesion which comprises applying the cosmetic or pharmaceutical composition of the present invention to the skin. Finally, the present invention relates to a method for reducing horny layer cell cohesion, and thereby promoting exfoliation, wherein said method comprises applying to the skin a cosmetic or pharmaceutical composition comprising an effective amount of at least one protease active on the polypeptide of the present invention.
    Type: Grant
    Filed: December 29, 1999
    Date of Patent: November 11, 2003
    Assignee: Societe L'Oreal S.A.
    Inventors: Guy Bruno Rene Serre, Michel Simon, Marina Weber-Vivat
  • Patent number: 6627603
    Abstract: A method for the controlled release of an active principle contained in a multiple water-in-oil-in-water emulsion characterized in that the multiple emulsion comprises an invert emulsion Ei with an aqueous phase A1 containing at least a hydrophilic active principle. The emulsion Ei is dispersed in the form of direct emulsion droplets Ed, in a continuous aqueous phase A2, with the two emulsions Ed and Ei stabilized by at least a surfactant, present in their respective continuous phases. The multiple emulsion is brought in the presence of an effective amount of an agent for transforming it into a direct emulsion and induce the release of the active principle, contained in the aqueous phase A1 of emulsion Ei, in the aqueous phase A2.
    Type: Grant
    Filed: August 10, 1999
    Date of Patent: September 30, 2003
    Assignee: Centre National de la Recherche Scientifiquue (C.N.R.S.)
    Inventors: Jérôme Bibette, Marie-Françoise Ficheux, Fernando Leal Calderon, Lida Bonnakdar
  • Patent number: 6617314
    Abstract: The present application relates to injection formulations of avermectins and milbemycins based on a solvent mixture comprising sesame oil, medium-chain triglycerides, glycol esters or fatty acid esters and a further solvent from the group consisting of mono- or polyhydric aliphatic or aromatic alcohols and their derivatives (e.g. cyclic carbonates; acetates; acetals; ketals) or castor oil.
    Type: Grant
    Filed: March 10, 1999
    Date of Patent: September 9, 2003
    Assignee: Bayer Aktiengesellschaft
    Inventors: Michael Grosse-Bley, Richard Kujanek
  • Patent number: 6602511
    Abstract: A non-toxic oil-in-water or bicontinous microemulsion used as a pharmaceutically acceptable vehicle for administration of one or more active compounds having a low solubility in water as well as a process for the preparation and the use thereof.
    Type: Grant
    Filed: September 30, 1996
    Date of Patent: August 5, 2003
    Assignee: AstraZeneca AB
    Inventor: Christian von Corswant
  • Patent number: 6596779
    Abstract: The present invention relates to emulsions which remain perfectly stable over time, prepared from an emulsifier comprising at least one polyglycoside, i.e. polypentoside with or without pohexoside, in which the aliphatic radical has 16 to 18 carbon atoms, and at least one fatty alcohol having 12 to 22 carbon atoms; a process for stabilizing the emulsions; and an emulsifying agent.
    Type: Grant
    Filed: February 7, 2000
    Date of Patent: July 22, 2003
    Assignee: Agro Industrie Recherches et Developpements
    Inventors: Bertmo Jean-Noel, Mathaly Philippe, Régis de Baynast, Dubois Véronique
  • Patent number: 6576678
    Abstract: The invention relates to emulsion bases containing (a) polyol poly-12-polyhydroxystearates, (b) polyol esters selected from the group consisting of sorbitan esters, oligoglycerol esters and partial glycerides, (c) citric acid esters, (d) waxes and (e) metal soaps. The emulsion bases are distinguished by the fact that they enable both stable creams and lotions to be produced, irrespective of the polarity of the oils combined therewith.
    Type: Grant
    Filed: February 9, 2001
    Date of Patent: June 10, 2003
    Assignee: Cognis Deutschland GmbH & Co. KG
    Inventors: Stefan Bruening, Achim Ansmann, Gabriele Strauss
  • Patent number: 6562372
    Abstract: A tocotrienol-containing powder prepared by a process wherein an oil containing a tocotrienol is treated with a lecithin, a cellulose and an emulsifying agent in water to form an emulsion, a powder substance is mixed with the formed emulsion to form a suspension and then the formed suspension is spray-dried. The powder containing tocotrienol, which has excellent storage stability and free flowability, can be used in preparing a tablet which comprises the powder compressed into a tablet form.
    Type: Grant
    Filed: April 5, 2000
    Date of Patent: May 13, 2003
    Assignee: Fuji Chemical Industry Co., Ltd.
    Inventors: Shinichiro Yokoi, Nobukazu Tanaka, Yoshiharu Horita, Terumasa Hosokawa, Takeshi Shishido, Heiji Ikushima
  • Patent number: 6562876
    Abstract: A process for cold-producing an oil-in-water emulsion having enhanced consistency and tactile properties involving: (a) providing an oil component; (b) providing an aqueous wax dispersion containing: (i) a wax component; and (ii) an emulsifier; (c) providing water; and (d) cold-stirring (a)-(c) to form the emulsion.
    Type: Grant
    Filed: April 23, 2001
    Date of Patent: May 13, 2003
    Assignee: Cognis Deutschland GmbH & Co. KG
    Inventors: Achim Ansmann, Nicole Mertscheit, Rolf Kawa