Abstract: An analgesia composition comprising an aqueous solution of a neurologically active agent in a concentration of from about 10.sup.-3 to about 10.sup.-13 grams/ml and a method of relieving pain comprising topically applying the composition to the genitalia of a human or non-human animal.
Abstract: A cosmetic preparation contains, as a fatty phase, karite oil having the following characteristics: palmitic acid (C.sub.16), 3-5 percent; stearic acid (C.sub.18), 22-30 percent; oleic acid (C.sub.18:1), 55-65 percent; linoleic acid (C.sub.18:2), 0.5-1.5 percent; and arachidic acid (C.sub.20), 0.5-1.5 percent, said percentages being based on the total weight of fatty acid present in said karite oil, a viscosity of 100-300 centipoises, a melting point of 5.1.degree.-5.4.degree. C., a crystallization temperature of 2.9.degree.-3.degree. C. and an unsaponifiable content of 1.2-1.5 percent.
Abstract: A topical preparation for treating an epidermal area of a human being infected with Herpes simplex virus comprising a stable solution or emulsion of from approximately 30% by volume to approximately 50% by volume of anhydrous ethyl ether in a pharmaceutically acceptable carrier oil of vegetable origin of about C.sub.6 to C.sub.20, having most of the free fatty acids thereof removed, said emulsion having a boiling point of at least 100.degree. F. The oils are preferably lauric acid oils. The method for treating in vivo an epidermal area of a human being infected with Herpes simplex virus includes the step of applying to the infected area in an amount sufficient to cover the infected area the topical preparation. In another embodiment of the method heat subsequently is applied to the area to which the topical preparation is applied.
Abstract: A topical preparation for treating an epidermal area of a human being infected with Herpes simplex virus comprising a stable emulsion having from approximately 30% by volume to approximately 50% by volume of anhydrous ethyl ether in a pharmaceutically acceptable coconut oil carrier having most of the free fatty acids thereof removed, said emulsion having a boiling point of at least 100.degree. F. The method for treating in vivo an epidermal area of a human being infected with Herpes simplex virus includes the step of applying to the infected area in an amount sufficient to cover the infected area the topical preparation. In another embodiment of the method heat subsequently is applied to the area to which the topical preparation is applied. In one preferred mode of this embodiment of the method the heat is applied approximately three minutes after the topical preparation is applied and the application of heat maintained for a period of between about 3 and 15 minutes.
Abstract: The subject invention concerns a novel, unobvious, and useful composition of matter and method for tanning the human epidermis. The composition comprises a suitable dye precursor, peroxidase and H.sub.2 O.sub.2. These ingredients, when reacted together on the skin, result in the formation of melanin-like dyes which tan the skin.
Abstract: A method of percutaneously administering metoclopramide which comprises applying to the skin of a mammal metoclopramide in a carrier system which comprises at least one adjuvant and at least one solvent. The adjuvant is a monovalent alcohol ester of an aliphatic monocarboxylic acid or an aliphatic monoalcohol. The solvent is a pyrrolidone-type compound. Mixtures can also be used.
Type:
Grant
Filed:
February 1, 1984
Date of Patent:
August 12, 1986
Assignee:
Nitto Electric Industrial Co., Ltd.
Inventors:
Kenichiro Saito, Jorge Heller, Wilfred A. Skinner
Abstract: A composition capable of promoting the skin permation or percutaneous absorption of a medicament, which comprises at least one adjuvant selected from the group consisting of a saturated hydrocarbon containing 5 to 20 carbon atoms which may be substituted by halogen, an alcohol ester of aliphatic carboxylic acid containing 12 to 18 carbon atoms, an ether, a dimethylpolysiloxane having a viscosity at 25.degree. C. of not more than 6 centistokes and a cyclic polydimethylsiloxane having a viscosity at 25.degree. C. of not more than 6 centistokes, and an imidazolidinone derivative represented by the general formula: ##STR1## wherein R.sub.1 and R.sub.2 each are a lower alkyl group; and pharmaceutical composition for external medication.
Abstract: An absorbable biologically compatible putty-like composition is used as a matrix from which immunologically or pharmacologically active agents, such as antibiotics, can be introduced into the body to provide a slow sustained release of the agent over an extended period of time. A preferred matrix comprises a mixture of calcium stearate, dextran and castor oil.
Type:
Grant
Filed:
February 8, 1985
Date of Patent:
February 4, 1986
Assignee:
Ethicon, Inc.
Inventors:
Richard L. Kronenthal, Frank V. Mattei, Alan J. Levy
Abstract: A pharmaceutical preparation for external use which comprises a solution of a non-steroid antipholgistic analgesic agent which is dissolved in at least one adjuvant selected from the group consisting of peppermint oil, methyl salicylate, ethyl salicylate and monoglycol salicylate in an amount at least sufficient to dissolve said antipholgistic analgesic agent, and bases for external use.
Abstract: There is described a sterile ointment basis, suitable for use in the eye, comprising one or more paraffins and acetylated lanolin.There is also described an ointment comprising an active ingredient, e.g. an antiallergic drug, and the ointment basis.There is further described a process for the manufacture in a medicament container of the ointment comprising an active ingredient.
Abstract: This invention relates to the preparation and use of glucuronide derivatives of anticholinergic compounds to render them safe for use in the control of human perspiration. These derivatives, which lack mydriatic potency in the eye, are applied to the axillae where they are rendered biologically active by the action of .beta.-glucuronidase occurring naturally on the skin.
Abstract: Paste for protecting the skin, fundamentally comprising:at least one hydrocolloid, insolubilized carboxymethylcellulose and/or another superabsorbent product derived from hydrocolloids, and a polyvinylpyrrolidone having a molecular weight of the order of 25,000 to 30,000, as thickeners,demineralized water as a binder, andto fix the latter, a suitable oil and a suitable stearate, and alsocrosslinked and insolubilized polyvinylpyrrolidone, and advantageouslysorbitol and/or polyethylene glycol.Application, in particular, for providing protection against weeping wounds and/or against matter flowing out of stomata from the urinary or digestive tract.