Compositions For Use In Tape Adhesives, Binder Or Impregnate For A Body Fluid Adsorbent Device, E.g., A Surgical Adhesive Tape, Etc. Patents (Class 523/111)
  • Patent number: 11439582
    Abstract: Aqueous compositions can be thickened without increasing stringiness, by using polymers of polyacrylic acid, poly(2-acryamide-2-methylpropanesulfonate), or salts thereof, having a weight average molecular weights of 500,000 to 8,000,000 as thickeners. The polymers contain no more than 10 mass % of polymers having a molecular weight of 10,000,00 or more, and/or contain no more than 10 mass % of polymers having more than three times the weight average molecular weight. Aqueous solutions of these polymers exhibit a low degree of stringiness, and are particularly useful as thickeners for cosmetics.
    Type: Grant
    Filed: October 16, 2017
    Date of Patent: September 13, 2022
    Assignee: SHISEIDO COMPANY, LTD.
    Inventors: Atsushi Sogabe, Ayano Matsuo, Shin-Ichi Yusa
  • Patent number: 11292944
    Abstract: Provided is an adhesive composition including lysine, citric acid, and water, wherein the lysine and the citric acid are present in the form of an aqueous solution of a salt such that precipitates are not formed in the aqueous solution. In addition, provided is a method of preparing an adhesive composition including mixing lysine, citric acid, and water to thereby form a mixture of the lysine, the citric acid, and the water, and stirring the mixture at a temperature of 80° C. or less, wherein amounts of the lysine, the citric acid, and the water are adjusted such that precipitates of the lysine and the citric acid do not form in the adhesive composition.
    Type: Grant
    Filed: March 21, 2018
    Date of Patent: April 5, 2022
    Assignee: CJ CHEILJEDANG CORPORATION
    Inventors: Ji Ho Hwang, Jun Ok Moon, Young Lyeol Yang, Chang Suk Lee, Sang Gwon Moon, Su Jin Choi
  • Patent number: 11242470
    Abstract: The invention includes a hot melt adhesive composition including an olefin polymer and a high melt point hydrocarbon tackifying agent, such compositions unexpectedly provide improved bonding between the layers found in a disposable absorbent article. In particular, such compositions improve the bond between the nonwoven top sheet and the acquisition distribution layer.
    Type: Grant
    Filed: November 30, 2018
    Date of Patent: February 8, 2022
    Assignee: H.B. Fuller Company
    Inventors: Steven R. Vaughan, Kevin P. Davis, Thomas Wittkopf, Peter Remmers, Seth Urtel
  • Patent number: 11109996
    Abstract: An ostomy appliance comprising an adhesive wafer (2) for attachment to a skin surface of a user. The adhesive wafer includes a backing layer (13), an adhesive layer (12), and at least one release liner (17). The release liner comprises an enclosure (9) capable of containing a liquid or a wipe (14). The enclosure (9) can be filled with liquid before removal from the wafer, thereby providing a temperature impact on the adhesive. The wipe (14) can be impregnated with an activating agent for providing an activation of the adhesive prior to use.
    Type: Grant
    Filed: September 23, 2016
    Date of Patent: September 7, 2021
    Assignee: Coloplast A/S
    Inventors: Esben Stroebech, Michael Hansen, Birthe Vestbo Andersen, Peter Kwok Hing Lam, Lars Olav Schertiger
  • Patent number: 10883026
    Abstract: The present invention relates to an adhesive producible from an aqueous polyurethaneurea dispersion comprising an amorphous polyurethaneurea (V1) obtainable by reacting at least A) one aliphatic, cycloaliphatic or araliphatic polyisocyanate component having an average isocyanate functionality of ?1.8 and ?2.
    Type: Grant
    Filed: December 13, 2018
    Date of Patent: January 5, 2021
    Assignee: Covestro Deutschland AG
    Inventors: Marc-Stephan Weiser, Sascha Plug, Sebastian Doerr
  • Patent number: 10869622
    Abstract: A body fluid leakage detection aqueous composition, for use e.g. in intraoperative pancreatic fluid leakage detection. The composition comprises a gelling agent, increasing the viscosity of the composition, and buffering species, the composition thereby being buffered. The gelling agent is cross-linked ?-glucan microspheres. Further, the composition comprises a pH-indicator. The pH of the composition is at least 0.1 pH units lower, or higher, than a pKa of the pH-indicator.
    Type: Grant
    Filed: December 20, 2018
    Date of Patent: December 22, 2020
    Assignees: MAGLE CHEMOSWED HOLDING AB, UNIVERSITÄT HEIDELBERG
    Inventors: Henrik Johansson, Peter Schuisky, Thomas Pausch, Thilo Hackert
  • Patent number: 10744224
    Abstract: Disclosed is an adhesive composition, devices including the adhesive composition and uses of the devices including the adhesive composition. The adhesive composition is for attachment to skin and includes an adhesive polymer component selected from a mixture of a polyethylene copolymer and polypropylene glycol (PPG), and styrene-ethylene/butylene-styrene (SEBS) block copolymer. The composition further includes polyolefin, polybutene, polyacrylic acid (PAA), and at least one further absorbent material.
    Type: Grant
    Filed: August 24, 2016
    Date of Patent: August 18, 2020
    Assignee: Coloplast A/S
    Inventors: Dorrit Diana Israelson, Henrik Olsen, Charlotte Klein
  • Patent number: 10441261
    Abstract: An apparatus for opening or closing a tissue opening in a biological subject, the apparatus including at least two flexible arms coupled to a tissue surface in use, each arm being curved outwardly in a mid-portion to accommodate a tissue opening therebetween and a biasing mechanism that selectively biases opposing ends of each arm to thereby at least one of bias mid-portions of the arms apart to assist in at least partially opening the tissue opening; and bias mid-portions of the arms towards each other to assist in at least partially closing the tissue opening.
    Type: Grant
    Filed: April 28, 2015
    Date of Patent: October 15, 2019
    Assignee: ROFFE MEDICAL HOLDINGS PTY LTD.
    Inventor: Kevin Marshall
  • Patent number: 10420557
    Abstract: A skin frame or other skin straining device strains skin on each side of a wound where a wound has been closed to off load stresses at the wound site. A dressing may be applied to the strained skin. The dressing may be integral with one or more elements of the skin straining device.
    Type: Grant
    Filed: May 31, 2016
    Date of Patent: September 24, 2019
    Assignee: Neodyne Biosciences, Inc.
    Inventors: Paul Yock, Reinhold H. Dauskardt, Jasper Jackson, John A. Zepeda, William R. Beasley
  • Patent number: 10213396
    Abstract: There is provided a patch to enhance locally fat metabolism, using a thermoplastic elastomer gel composition including capsaicin, which is applied to the skin surface, comprises: a skin adhering layer formed of the thermoplastic elastomer (TPE) gel including capsaicin, the skin adhering layer having a top surface and a bottom surface; a base layer secured to the bottom surface of the skin adhering layer, to support for the patch; and a removable paper/film layer secured to the top surface of the skin adhering layer, to protect the skin adhering layer prior to use, wherein the skin adhering layer comprises: 3˜12 wt % of styrene ethylene butylene styrene (SEBS) or styrene ethylene ethylene propylene styrene (SEEPS), 44˜53 wt % of an adhesive agent; 44˜53 wt % of mineral oil, and 0.001˜0.009 wt % of capsaicin. Capsaicin included in the TPE gel derives heat generation and fat breakdown, to help attain fat loss in the area where the patch is applied.
    Type: Grant
    Filed: July 13, 2017
    Date of Patent: February 26, 2019
    Assignee: SENNY STUDIO CO., LTD.
    Inventors: Kyu-Hak Cho, Seung-Wook Yoon
  • Patent number: 10172971
    Abstract: Absorbing articles comprises water absorbing resin including a water-soluble unsaturated monomer, having a dissociable group, as a main component in a repeating unit of a main chain and an internal cross-linked structure, in which a cross-linked structure index represented by the formula [Cross-linked structure index=(Equilibrium swelling capacity with respect to 0.9% by weight of brine)1/3/(Weight average molecular weight after hydrolysis treatment)×1,000,000] is 14 or more, a weight average molecular weight after hydrolysis treatment is 220,000 or less, and a molecular weight distribution after hydrolysis treatment is 3.40 or less, and a method for producing the same.
    Type: Grant
    Filed: February 19, 2015
    Date of Patent: January 8, 2019
    Assignee: The Procter & Gamble Company
    Inventors: Kazuyuki Oshima, Yoshiro Mitsukami, Taku Fujimoto, Erina Minami, Peter Dziezok, Marion Lutsche, Gabriela Schaefer
  • Patent number: 10124316
    Abstract: Disclosed herein is a superabsorbent polymer with a surface modified with both a polyvalent cationic salt and a polycarbonic acid-based copolymer, which is able to effectively absorb blood or highly viscous liquid, and a method for preparing the same.
    Type: Grant
    Filed: December 14, 2015
    Date of Patent: November 13, 2018
    Assignee: LG Chem, Ltd.
    Inventors: Young-Sam Kim, Yeon-Woo Hong, Dong-Jo Ryu
  • Patent number: 10112176
    Abstract: Disclosed herein is a superabsorbent polymer with a surface modified with both a water-soluble polyvalent cationic salt and a polycarbonic acid-based copolymer, wherein an improvement is brought about in processability without significant degradation of other properties and a method is provided for preparing the surface-modified superabsorbent polymer.
    Type: Grant
    Filed: December 14, 2015
    Date of Patent: October 30, 2018
    Assignee: LG Chem, Ltd.
    Inventors: Young-Sam Kim, Yeon-Woo Hong, Dong-Jo Ryu
  • Patent number: 10100160
    Abstract: Disclosed herein is a superabsorbent polymer with a surface crosslinked with a water-soluble polyvalent cationic salt, a polycarbonic acid-based copolymer, and a surface crosslinking agent wherein an improvement is brought about in physical properties, with the concomitant reduction of process time and cost. Also, a method is provided for preparing the surface-crosslinked superabsorbent polymer.
    Type: Grant
    Filed: December 14, 2015
    Date of Patent: October 16, 2018
    Assignee: LG Chem, Ltd.
    Inventors: Young-Sam Kim, Yeon-Woo Hong, Dong-Jo Ryu
  • Patent number: 10060052
    Abstract: Fibrous elements, for example filaments, containing an acrylamide-based copolymer, fibrous structures employing such fibrous elements, and methods for making same are provided.
    Type: Grant
    Filed: October 22, 2014
    Date of Patent: August 28, 2018
    Assignee: The Procter & Gamble Company
    Inventors: Matthew Gary McKee, Gregory Charles Gordon, Joerg Kleinwaechter, Mark Robert Sivik, Paul Dennis Trokhan
  • Patent number: 9980849
    Abstract: An ostomy appliance wafer is provided with a stoma-receiving hole formed through the wafer. The wafer includes a backing layer, and an absorbent layer located between a first adhesive and a second adhesive. The first adhesive is disposed over the backing layer to define a peripheral edge area, a central area surrounding the hole, and an intermediate area of the wafer that is located between the peripheral edge area and the central area. The absorbent layer is disposed on the first adhesive either in A) the central area of the wafer, B) the intermediate area of the wafer, or C) the central area and the intermediate area of the wafer. The second adhesive is disposed over both a portion of an outer edge area of the absorbent layer and a portion of the first adhesive peripheral to the outer edge area of the absorbent layer.
    Type: Grant
    Filed: February 12, 2016
    Date of Patent: May 29, 2018
    Assignee: Coloplast A/S
    Inventor: Peter Kwok Hing Lam
  • Patent number: 9884452
    Abstract: A method of bonding substrates includes steps as follows. Providing a curved glass substrate and a flexible light-transmissive film; moving a roller to press the flexible light-transmissive film onto the curved glass substrate so that the flexible light-transmissive film matches a curvature of the curved glass substrate to gradually fit and bond onto the curved glass substrate; sensing the attaching level of at least one local area of the flexible light-transmissive film bonded on the curved glass substrate; and adjusting a press force exerted by the roller to the local area of the flexible light-transmissive film according to the attaching level during the flexible light-transmissive film is bonded onto the curved glass substrate.
    Type: Grant
    Filed: April 8, 2016
    Date of Patent: February 6, 2018
    Assignee: Quanta Computer Inc.
    Inventors: Ching-Chih Chen, Lin-Huei Wang, Lai-Peng Lai, Ying-Cheng Chen
  • Patent number: 9801971
    Abstract: Transdermal therapeutic systems that contain 4-n-butylresorcinol as an active ingredient.
    Type: Grant
    Filed: July 14, 2010
    Date of Patent: October 31, 2017
    Assignee: BEIERSDORF AG
    Inventors: Karl-Heinz Woeller, Ludger Kolbe, Cathrin Scherner, Rainer Wolber
  • Patent number: 9764058
    Abstract: The present invention relates to a method that includes providing a formulation having an isocyanate-functional prepolymer and a curing component comprising an amino-functional aspartic ester of the general formula (I) applying the formulation to a cell tissue; and curing the formulation such that the loss of blood (haemostatic) or tissue fluids is staunched or leaks in cell tissues are sealed.
    Type: Grant
    Filed: July 4, 2009
    Date of Patent: September 19, 2017
    Assignee: Adhesys Medical GmbH
    Inventors: Heike Heckroth, Burkhard Köhler, Sebastian Dörr
  • Patent number: 9763453
    Abstract: The present invention provides antimicrobial coatings for coating substrate surfaces, particularly medical devices, for preventing bacterial adhesion and biofilm formation by inhibiting microbial growth and proliferation on the coating surface. The antimicrobial coatings are composed of a hydrogel and a bioactive agent including a substantially water-insoluble antimicrobial metallic material that is solubilized within the coating. Antimicrobial coating formulations for obtaining such coatings, and coating methods are also described.
    Type: Grant
    Filed: May 2, 2014
    Date of Patent: September 19, 2017
    Assignee: Bacterin International, Inc.
    Inventors: Guy S. Cook, Matt R. Trebella
  • Patent number: 9617400
    Abstract: A film formed from a water-soluble polymer matrix containing a fragrance is provided. The film is water-sensitive so that upon contact with a sufficient amount of water, the matrix loses its integrity to increasingly expose the fragrance to the ambient environment for releasing its odor. The ability to incorporate a fragrance into the matrix is achieved by controlling the nature of the fragrance and polymer, the manner in which the matrix and fragrance are melt processed, etc. For example, the fragrance may be injected directly into the extruder and melt blended with the polymer to avoid the costly, time-consuming steps of pre-encapsulation or pre-compounding of the fragrance into a masterbatch. Furthermore, to balance the fragrance's ability to release the desired odor during use while minimizing the premature exhaustion of the odor during processing, the fragrance has a boiling point (at atmospheric pressure) of from about 125° C. to about 350° C.
    Type: Grant
    Filed: October 30, 2014
    Date of Patent: April 11, 2017
    Assignee: Kimberly-Clark Worldwide, Inc.
    Inventors: Sarah A. Funk, James Hongxue Wang
  • Patent number: 9492329
    Abstract: Devices, kits and methods described herein may be for wound healing, including the treatment, amelioration, or prevention of scars and/or keloids by applying and/or maintaining a predetermined strain in an elastic skin treatment device that is then affixed to the skin surface using skin adhesives to transfer a generally planar force from the bandage to the skin surface. Applicators are used to apply and/or maintain the strains, and some of the applicators are further configured to provide at least some mechanical advantage to the user when exerting loads onto the skin treatment device.
    Type: Grant
    Filed: January 17, 2014
    Date of Patent: November 15, 2016
    Assignee: Neodyne Biosciences, Inc.
    Inventors: John A. Zepeda, Jasper Jackson, William R. Beasley, Darren G. Doud, Brett A. Follmer
  • Patent number: 9433636
    Abstract: Bodily tissue and structures may be protected using a fluid layer containing a mixture of chitosan and oxidized polysaccharide. The mixture forms a protective gel layer via in situ crosslinking. Compared to crosslinking using a low molecular weight aldehyde such as glutaraldehyde or genipin, oxidized polysaccharides appear to provide faster gelation while avoiding the use of potentially less bioacceptable low molecular weight aldehydes.
    Type: Grant
    Filed: April 23, 2009
    Date of Patent: September 6, 2016
    Assignee: Medtronic, Inc.
    Inventors: Edze Jan Tijsma, Maria Nieves Gonzalez, Erica M. TenBroek, Nancy Schaffhausen
  • Patent number: 9346981
    Abstract: Methods for incorporating chlorhexidine salts into solvent based adhesives are described. The methods involve freeze drying an aqueous solution of the chlorhexidine salt and obtaining the chlorhexidine salt in a particulate form. The dry powder can then be dissolved into an appropriate solvent used with the adhesive of interest. Also described are particles including chlorhexidine salts that are incorporated in adhesives. Also described are various medical products utilizing the adhesive and chlorhexidine compound, and related methods of use.
    Type: Grant
    Filed: January 23, 2012
    Date of Patent: May 24, 2016
    Assignee: Avery Dennison Corporation
    Inventors: Anne Marie Wibaux, Vicky Van de Pol
  • Patent number: 9289322
    Abstract: An ostomy appliance comprising an adhesive wafer for attachment to the body, the wafer comprising a skin facing surface and a non skin-facing surface, the non skin-facing surface being provided with a backing layer, the skin facing surface of the wafer comprises a central area comprising a substantially non-absorbent protective adhesive, an intermediate area surrounding the central area, said area comprising a substantially non-absorbent soft adhesive, and an edge area surrounding the intermediate area, said edge area comprising a substantially non-absorbent protective adhesive.
    Type: Grant
    Filed: December 20, 2011
    Date of Patent: March 22, 2016
    Assignee: Coloplast A/S
    Inventor: Peter Kwok Hing Lam
  • Patent number: 9200109
    Abstract: The present invention provides a polymerizable adhesive composition comprising: (i) at least one cyanoacrylate monomer; and (ii) at least one polymerizable compound containing (a) one or more polymerizable carbon-carbon double bonds and (b) one or more biodegradable (BDG) chains. Further are provided the copolymerization product of this composition, and uses thereof in biomedical applications.
    Type: Grant
    Filed: September 6, 2009
    Date of Patent: December 1, 2015
    Assignee: YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM, LTD.
    Inventors: Daniel Cohn, Peter Siman
  • Patent number: 9089606
    Abstract: The objects of the present invention are: to provide a therapeutic agent and a therapeutic method for periodontal diseases and pulpal diseases, a transplant for periodontal tissue regeneration, and a method for regenerating the periodontal tissue. According to the present invention, there are provided therapeutic agents for periodontal diseases and pulpal diseases which comprise neurotrophic factors as an active ingredient.
    Type: Grant
    Filed: March 16, 2012
    Date of Patent: July 28, 2015
    Assignees: TWO CELLS CO., LTD.
    Inventors: Hidemi Kurihara, Hiroyuki Kawaguchi, Katsuhiro Takeda, Hideki Shiba, Noriyoshi Mizuno, Hiroshi Yoshino, Naohiko Hasegawa, Hiroaki Shinohara
  • Patent number: 9012415
    Abstract: This invention refers to photo-crosslinked hydrogel materials based in gellan gum suitable for tissue engineering and regenerative medicine applications or as drug delivery systems. Formulations of gellan gum with different degrees of acylation serve as precursor material for insertion of a polymerizable moiety. The materials are capable of free radical polymerization with a photo-initiator at mild temperatures and exposure to ultraviolet light, enabling control of reticulation and withstanding the encapsulation of human and animal cells and/or drugs, and any combination thereof. The physicochemical and biological properties can be adjusted by combining different formulations of gellan gum and reaction conditions.
    Type: Grant
    Filed: March 26, 2011
    Date of Patent: April 21, 2015
    Assignee: Stemmatters, Biotecnologia e Medicina Regenerativa S.A.
    Inventors: Joana Catarina Da Silva Correia, Joaquim Miguel Antunes De Oliveira, João Manuel Teixeira De Oliveira, Rui Pedro Amandi Romero De Sousa, Rui Luis Gonçalves Dos Reis
  • Patent number: 9012530
    Abstract: The invention is directed to an adhesive strip, particularly an adhesive strip or bandage for use in periodontal treatments. The biocompatible adhesive strip comprises a flexible barrier with a biocompatible adhesive for use in an oral environment, wherein the adhesive is in a non-tacky state when dry and becomes adherent upon contact with liquids.
    Type: Grant
    Filed: July 30, 2010
    Date of Patent: April 21, 2015
    Assignee: Warsaw Orthopedic, Inc.
    Inventors: Kelly Brook Emerton, Susan J. Drapeau, Daniel Andrew Shimko
  • Patent number: 9005406
    Abstract: A method and a system for producing a change in a medium. The method places in a vicinity of the medium at least one energy modulation agent. The method applies an initiation energy to the medium. The initiation energy interacts with the energy modulation agent to directly or indirectly produce the change in the medium. The system includes an initiation energy source configured to apply an initiation energy to the medium to activate the energy modulation agent.
    Type: Grant
    Filed: January 16, 2014
    Date of Patent: April 14, 2015
    Assignee: Immunolight, LLC
    Inventor: Frederic A. Bourke, Jr.
  • Patent number: 8912247
    Abstract: Improved methods for preparing polyethylene glycol fumarate) are disclosed. Methods for chemically crosslinking or photocross-linking hydrophilic polyethylene glycol fumarate) with hydrophobic polymers such as poly(propylene fumarate) (PPF) and poly(caprolactone fumarate) (PCLF) to form various hydrogels (FIG. 1) with controllable hydrophilicity are also disclosed. The hydrogels are useful in the fabrication of injectable and in-situ hardening scaffolds for application in skeletal reconstruction. An injectable material including the hydrogels may be useful in controlled drug release.
    Type: Grant
    Filed: April 28, 2006
    Date of Patent: December 16, 2014
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Shanfeng Wang, Lichun Lu, Michael J. Yaszemski
  • Patent number: 8906980
    Abstract: The present invention relates to a water-soluble polymer composition which comprises a water-soluble poly(meth)acrylic polymer and a gelation rate retarding agent, and a composition for forming a plaster layer of a skin patch which is obtainable by adding a polyvalent metal compound to the water-soluble polymer composition. When a polyvalent metal compound is added, the aforesaid water-soluble polymer composition shows an appropriate induction period before the start of the hardening of the gel. When the water-soluble polymer composition is used for forming a plaster layer of a skin patch, therefore, additive ingredients can be uniformly mixed and the procedure for coating to a support can be facilitated.
    Type: Grant
    Filed: July 22, 2010
    Date of Patent: December 9, 2014
    Assignee: Sumitomo Seika Chemicals Co., Ltd
    Inventor: Kazuyuki Miura
  • Publication number: 20140348896
    Abstract: Pre-polymers for use as tissue sealants and adhesives, and methods of making and using thereof are provided. The pre-polymers have flow characteristics such that they can be applied through a syringe or catheter but are sufficiently viscous to remain in place at the site of application and not run off the tissue. The pre-polymers are also sufficiently hydrophobic to resist washout by bodily fluids. The pre-polymers are stable in bodily fluids; that is the pre-polymer does not spontaneously crosslink in bodily fluids absent the presence of an intentionally applied stimulus to initiate crosslinking. Upon crosslinking, the adhesive exhibits significant adhesive strength in the presence of blood and other bodily fluids. The adhesive is sufficiently elastic that it is able to resist movement of the underlying tissue. The adhesive can provide a hemostatic seal. The adhesive is biodegradable and biocompatible, causing minimal inflammatory response.
    Type: Application
    Filed: May 23, 2014
    Publication date: November 27, 2014
    Applicants: Massachusetts Institute of Technology, The Brigham and Women's Hospital, Inc., The Children's Medical Center Corporation
    Inventors: Jeffrey M. Karp, Pedro del Nido, Nora Lang, Robert S. Langer, Maria Jose M.N. Pereira, Yuhan Lee
  • Patent number: 8877882
    Abstract: Liquid adhesive coating materials are prepared that protect surfaces, such as medical devices and biological surfaces, including skin and mucous membranes, from pressure, shear, and friction. The liquid coating materials utilize an amphiphilic siloxysilane/hydroxyalkyl ester polymer-containing coating material dissolved in a volatile solvent, with or without an antimicrobial agent, where when the polymer coating is formed after solvent evaporation and is folded against itself or placed against another material, the surface of said coating does not adhere, while the bottom of the coating remains attached to the original surface.
    Type: Grant
    Filed: October 4, 2013
    Date of Patent: November 4, 2014
    Assignee: Rochal Industries LLP
    Inventors: Joseph Charles Salamone, Katelyn Elizabeth Reilly, Ann Beal Salamone, Xiaoyu Chen
  • Patent number: 8846845
    Abstract: Absorbable polyurethanes, polyamides and polyester urethanes prepared from at least one compound selected from: or the corresponding diamines or diisocyanates thereof, wherein each X independently represents —CH2COO—, —CH(CH3)COO—, —CH2CH2OCH2COO—, —CH2CH2CH2CH2CH2COO—, —(CH2)yCOO— where y is 2 to 4 or 6 to 24, or —(CH2CH2O)z?CH2COO— where z? is 2 to 24; each Y represents —COCH2O—, —COCH(CH3)O—, —COCH2OCH2CH2O—, —COCH2CH2CH2CH2CH2O—, —CO(CH2)mO— where m is 2 to 4 or 6 to 24, or —COCH2O(CH2CH2O)n— where n is 2 to 24; R? is hydrogen, benzyl or straight-chained or branched alkyl; p is 1 to 4; and Rn represents one or more members selected from H, alkoxy, benzyloxy, aldehyde, halogen, carboxylic acid and —NO2, which is attached directly to an aromatic ring or attached through an aliphatic chain. Absorbable polymers prepared from these compounds are useful for drug delivery, tissue engineering, tissue adhesives, adhesion prevention and other implantable medical devices.
    Type: Grant
    Filed: February 22, 2012
    Date of Patent: September 30, 2014
    Assignee: Bezwada Biomedical, LLC
    Inventor: Rao S. Bezwada
  • Patent number: 8809615
    Abstract: An adhesive preparation comprising a stretchable support and an adhesive layer laminated on at least one side of the support, wherein the stretchable support comprises a interlock woven fabric subjected to crimping processing, the adhesive layer contains 10% by mass or more of methyl salicylate with respect to the total mass of the layer, the whole adhesive preparation has moisture permeability of 1 to 350 g/m2·24 hr measured at a temperature of 40° C. and a relative humidity of 90%, and the methyl salicylate has a plasma AUC0-24 ranging from 3.0 to 60.0 ng·hr/mL in terms of a mean±standard deviation, and salicylic acid as a metabolite of the methyl salicylate has a plasma AUC0-24 ranging from 5000 to 13000 ng·hr/mL in terms of a mean±standard deviation, when the adhesive preparation is applied to a human skin for 8 hours such that an application amount of the adhesive layer applied is 50 to 300 g/m2 and a contact area is 280 cm2.
    Type: Grant
    Filed: October 26, 2009
    Date of Patent: August 19, 2014
    Assignee: Hisamitsu Pharmaceutical Co., Inc.
    Inventors: Kiyomi Tsuruda, Shinji Yamasoto, Kouki Shoho, Masaru Nakanishi
  • Patent number: 8809417
    Abstract: The present invention relates to a pressure sensitive paste composition for skin application. The paste comprises 10-50% (w/w) based on the total paste formulation of a blend of polar polyethylene copolymer(s) and polar oil.
    Type: Grant
    Filed: December 18, 2009
    Date of Patent: August 19, 2014
    Assignee: Coloplast A/S
    Inventor: Dorrit Diana Israelson
  • Patent number: 8753669
    Abstract: An adhesive composition is provided that contains both a hydrophobic phase and a hydrophilic phase, wherein the hydrophobic phase is composed of a hydrophobic polymer composition and the hydrophilic phase is a water-absorbent blend of a hydrophilic polymer and a complementary oligomer capable of crosslinking the hydrophilic polymer through hydrogen bonding, ionic bonding, and/or covalent bonding. The composition is useful as a bioadhesive, for affixing drug delivery systems, wound dressings, bandages, cushions, or the like to a body surface such as skin or mucosal tissue.
    Type: Grant
    Filed: August 20, 2007
    Date of Patent: June 17, 2014
    Assignees: A.V. Topchiev Institute of Petrochemical Synthesis, Russian Academy of Sciences, Corium International, Inc.
    Inventors: Gary W. Cleary, Mikhail M. Feldstein, Valery G. Kulichikhin, Danir F. Bairamov
  • Patent number: 8679581
    Abstract: Silicone pressure sensitive adhesive compositions including amphiphilic copolymers. The amphiphilic copolymers are based on a polydimethylhydrogensiloxane or polydimethylsiloxane based macroinitiator. A medical device including said pressure sensitive adhesive compositions for securing the device to human skin or tissue.
    Type: Grant
    Filed: July 7, 2010
    Date of Patent: March 25, 2014
    Assignee: Convatec Technologies, Inc.
    Inventors: Mahesh Sambasivam, James Crivello
  • Patent number: 8664293
    Abstract: A water based polymeric dispersion for PSA adhesive preparation for transdermal system comprising: a) an aqueous dispersion of a polymer of an acrylate and/or a methacrylate ester, b) a plasticizer c) a shrinkage reducing agent able to reduce the shrinkage of the water PSA dispersion when spread onto a surface to width values lower than 20 mm after 3 minutes rest.
    Type: Grant
    Filed: March 17, 2005
    Date of Patent: March 4, 2014
    Assignee: Pharmafilm S.R.L.
    Inventors: Francesco Cilurzo, Paola Minghetti
  • Patent number: 8617647
    Abstract: An adhesive composition is provided that is water-insoluble yet water-absorbent, i.e., capable of absorbing up to 15 wt. % water or more. The composition in composed of a film-forming hydrophilic polymer with at least one linear segment having a plurality of recurring polar groups along the polymer backbone, a complementary multifunctional polymer with a plurality of recurring functional groups that noncovalently bind to the polar groups on the film-forming polymer, and plasticizer. A method for manufacturing the adhesive composition is provided as well.
    Type: Grant
    Filed: August 24, 2012
    Date of Patent: December 31, 2013
    Assignees: A.V. Topchiev Institutes of Petrochemical Synthesis, Russian Academy of Sciences, Corium International, Inc.
    Inventors: Mikhail M. Feldstein, Danir F. Bairamov, Mikhail Borisovich Novikov, Valery G. Kulichikhin, Nicolai A. Platé, Gary W. Cleary, Parminder Singh
  • Patent number: 8603451
    Abstract: The present invention relates to compositions of cyanoacrylate monomer, a method of improving the viscosity and the curing speed with a single additive and a process of providing sterilized cyanoacrylate adhesive compositions for application in the medical field.
    Type: Grant
    Filed: May 22, 2012
    Date of Patent: December 10, 2013
    Assignee: Adhezion Biomedical, LLC
    Inventors: Sheng Zhang, Rafael Ruiz
  • Patent number: 8598404
    Abstract: A film that is biodegradable and water-sensitive (e.g., water-soluble, water-dispersible, etc.) in that it loses its integrity over time in the presence of water is provided. The film contains a biodegradable polyester, starch, water-soluble polymer, and plasticizer. The desired water-sensitive attributes of film may be achieved in the present invention by selectively controlling a variety of aspects of the film construction, such as the nature of the components employed, the relative amount of each component, the manner in which the film is formed, and so forth.
    Type: Grant
    Filed: September 14, 2012
    Date of Patent: December 3, 2013
    Assignee: Kimberly-Clark Worldwide, Inc.
    Inventors: James H. Wang, Bo Shi
  • Patent number: 8592641
    Abstract: A film that is biodegradable and water-sensitive (e.g., water-soluble, water-dispersible, etc.) in that it loses its integrity over time in the presence of water is provided. More specifically, the film contains a combination of a biodegradable polyester and a water-sensitive thermoplastic starch. The desired water-sensitive attributes of film may be achieved in the present invention by selectively controlling a variety of aspects of the film construction, such as the nature of the components employed, the relative amount of each component, the manner in which the film is formed, and so forth.
    Type: Grant
    Filed: December 15, 2006
    Date of Patent: November 26, 2013
    Assignee: Kimberly-Clark Worldwide, Inc.
    Inventors: James H. Wang, Bo Shi
  • Publication number: 20130303654
    Abstract: A biological coating material that includes a polymerizable polyacrylate monomer; a volatile liquid; a polymer selected from a synthetic rubber, a natural rubber, and a thermoplastic elastomer. The biological liquid coating material forms a coating or bandage in the form of a film that when applied and adhered to a surface or to the skin of a user inhibits the application surface from adhering to another surface.
    Type: Application
    Filed: July 22, 2013
    Publication date: November 14, 2013
    Applicant: Rochal Industries LLP
    Inventors: Ann Beal Salamone, Joseph C. Salamone
  • Patent number: 8575276
    Abstract: Synthesis methods for creating polymeric compounds comprising dihydroxyphenyl derivatives (DHPD), or DHPp i.e. polymers modified with DHPD, with desired surface active effects are described. The polymer backbone of DHPp has structural or performance features that can be tailored to control physical properties of DHPp, allowing it to be useful for different applications i.e. tissue adhesives or sealants, adhesion promoting coatings, and antifouling coatings.
    Type: Grant
    Filed: September 26, 2011
    Date of Patent: November 5, 2013
    Assignee: KNC NER Acquisition Sub, Inc.
    Inventor: Bruce P. Lee
  • Patent number: 8551519
    Abstract: Novel bioabsorbable and/or biocompatible polyurethanes, polyureas, polyamideurethanes and polyureaurethanes with tunable physical, mechanical properties and hydrolytic degradation profiles are provided for use in biomedical applications such as stents, stent coatings, scaffolds, foams, and films. The disclosed polymers may be derived from biocompatible and/or bioabsorbable polyisocyanates. The present invention also relates to new and improved methods for the preparation of the biocompatible and/or bioabsorbable polyisocyanates.
    Type: Grant
    Filed: November 26, 2012
    Date of Patent: October 8, 2013
    Assignee: Bezwada Biomedical, LLC
    Inventor: Rao S Bezwada
  • Publication number: 20130260137
    Abstract: An adhesive composition is disclosed that comprises acrylic adhesive particles having an average diameter of 10 to 100 micrometers obtained by suspension polymerization of an acrylic monomer mixture which comprises a branched C 14-22 alkyl group containing (meth)acrylate and a polar monomer. The adhesive composition may be applied to an adhesive dressing or patch. The adhesive has excellent water vapor permeability, excellent adhesion to skin with low skin irritation when applied, less adhesive residue after peeling, and less keratin damage. The adhesive does not cause wetness or peeling from sweat while being worn.
    Type: Application
    Filed: March 4, 2011
    Publication date: October 3, 2013
    Inventors: Hiroko Akiyama, Yorinobu Takamatsu, Yoshiteru Kakinuma
  • Patent number: 8524797
    Abstract: A water-absorbent resin composition having an antimicrobial property, which suppresses the generation of dust of the antimicrobial agent. A water-absorbent resin composition comprising a water-absorbent resin and an antimicrobial agent comprising an inorganic compound carrying an antimicrobial metal, the water-absorbent resin composition being characterized in that the degree of generated dust of the water-absorbent resin composition is at most 100 CPM. The water-absorbent resin composition of the present invention can be suitably used as hygienic materials such as disposable diaper, sanitary napkin and incontinence pad; urine-absorbent materials for pets; materials for civil engineering and construction such as packing materials; drip absorbents; food freshness retaining materials such as cold-reserving agents; horticultural articles such as water-retaining materials for soils; and the like.
    Type: Grant
    Filed: October 24, 2005
    Date of Patent: September 3, 2013
    Assignee: Sumitomo Seika Chemicals Co., Ltd.
    Inventors: Takayasu Taniguchi, Tatsuya Oida, Yasuhiro Nawata
  • Patent number: 8497226
    Abstract: An object of the present invention is to provide a water absorbent having excellent gel properties and showing excellent properties when used in a water-absorbing material of a sanitary/hygienic material such as paper diaper. Moreover, another object of the present invention is to provide a water absorbent which is safe and excellent in liquid permeability, and in which an amount of liquid permeability improver for improving the liquid permeability is reduced. The water absorbent is made from a water-absorbing resin prepared by a specific polymerization method and having a high degree of cross-linking, a high liquid holding property and a high gel strength (its swelling pressure of gel layer of is 35 kdyne/cm2 or more). This water absorbent is further processed to have a particular particle size distribution (95 wt % or more of its particles are less than 850ƒÊm but not less than 106ƒÊm, and logarithmic standard deviation (ƒĐƒÄ) is in a range of 0.25 to 0.
    Type: Grant
    Filed: August 13, 2010
    Date of Patent: July 30, 2013
    Assignee: Nippon Shokubai Co., Ltd.
    Inventors: Kazushi Torii, Hirofumi Shibata, Taku Iwamura, Yoshio Irie, Yorimichi Dairoku, Yoshiro Mitsukami, Sayaka Machida