Nonmedicated Composition Specifically Intended For Contact With Living Animal Tissue Or Process Of Preparing; Other Than Apparel Patents (Class 523/105)
  • Patent number: 10414864
    Abstract: The present invention is directed to a novel group of amino acid-based poly(ester urea)s (PEUs) for use in biodegradable adhesive and related methods for their making and use. These novel amino acid-based PEUs have a wide variation in mechanical properties and degradation behavior that can be tuned by varying the amino acids and polyols used to form the polyester monomers that form the PEUs. Importantly, these novel PEUs have been shown to be non-toxic in vitro and in vivo and may be suitable to a wide variety of biomedical and other uses. In some embodiments, the adhesive properties of these degradable amino acid-based poly(ester urea) adhesives has been further improved by the incorporation of controlled amounts of catechol functional groups into the side chains of the PEU via post-polymerization functionalization chemistry.
    Type: Grant
    Filed: July 21, 2015
    Date of Patent: September 17, 2019
    Inventors: Matthew Becker, Jinjun Zhou, Adrian Defante, Ali Dhinojwala
  • Patent number: 10406016
    Abstract: The splint kit provides a sealed splint, bandaging, and a water source for setting the splint. Different kits may be needed depending upon the size of the user to which the splint will be applied. The kits may also vary according to the body part to be set. The size of each splint is based upon the size of the user and the size of the body part(s) to be splinted to eliminate the need for the user to size the splint. The splint is self-contained in its own packaging to maintain the integrity of the splint. The fiberglass/hardening material is encased by a foam material and/or felt to further simplify the process of applying and setting the splint.
    Type: Grant
    Filed: March 29, 2016
    Date of Patent: September 10, 2019
    Assignee: READYSPLINTS L.L.C.
    Inventor: Robert J. Tomlinson
  • Patent number: 10395790
    Abstract: A transparent conductor including a Group 5 transition metal and boron, wherein the compound has a layered structure.
    Type: Grant
    Filed: November 12, 2014
    Date of Patent: August 27, 2019
    Inventors: Doh Won Jung, Hee Jung Park, Kimoon Lee, Yoon Chul Son, Woojin Lee, Youngjin Cho
  • Patent number: 10214607
    Abstract: Provided is a cell adhesion inhibitor which exhibits low cytotoxicity and an excellent cell adhesion prevention effect; a tool and an apparatus each having a surface modified through application of the cell adhesion inhibitor thereto; a method for producing each of the surface-modified tool and apparatus; a biomedical structure and a production method therefor; and a microchannel device and a production method therefor. The invention provides a cell adhesion inhibitor comprising, as an active ingredient, a polymer comprising a repeating unit having a sulfinyl group in a side chain thereof.
    Type: Grant
    Filed: February 22, 2016
    Date of Patent: February 26, 2019
    Inventors: Naoki Hayashi, Satoshi Hyugaji, Toshihiro Ogawa, Hidetoshi Miyamoto, Shin-ichirou Iwanaga
  • Patent number: 10172620
    Abstract: A staple cartridge assembly is used with a surgical stapler. The staple cartridge assembly includes a staple cartridge including a cartridge body, a cartridge deck, and a plurality of staples deployable from the cartridge body through the cartridge deck. The staple cartridge assembly includes a compressible adjunct positionable against the cartridge deck. The compressible adjunct includes a plurality of unaltered fibers and a plurality of altered fibers that are melted and resolidified. The unaltered fibers include a first fiber including a first fiber portion and a second fiber including a second fiber portion extending over the first fiber portion. The compressible adjunct further includes a node which comprises the first fiber portion, the second fiber portion, and at least a portion of the plurality of altered fibers, wherein the at least a portion of the plurality of altered fibers affixes the first fiber portion and the second fiber portion.
    Type: Grant
    Filed: September 30, 2015
    Date of Patent: January 8, 2019
    Assignee: Ethicon LLC
    Inventors: Jason L. Harris, Frederick E. Shelton, IV, Michael J. Vendely
  • Patent number: 10159652
    Abstract: Methods and devices for making particles at small volumes.
    Type: Grant
    Filed: October 16, 2014
    Date of Patent: December 25, 2018
    Assignee: The University of British Columbia
    Inventors: Colin Walsh, Andre Wild, Robert James Taylor, Timothy Leaver, Kevin Ou, Euan Ramsay, Aysha Ansari
  • Patent number: 10119119
    Abstract: A highly tunable bioscaffold is provided, as well as a method of manufacture of the bioscaffold and methods of use of the bioscaffold, for example for drug testing, cell propagation and for optimizing growth of a cell type, for example corneal endothelial cells.
    Type: Grant
    Filed: January 31, 2013
    Date of Patent: November 6, 2018
    Assignee: Carnegie Mellon University and University of Pittsburgh—Of the Commonwealth System of Higher Education
    Inventors: Adam Walter Feinberg, James L. Funderburgh, Rachelle Simko
  • Patent number: 10112177
    Abstract: The present invention relates to a sorbent for extracting polar components from a sample where the sorbent comprises a cross-linked polymer comprising nitrogen containing cyclic compounds, for example 1-vinylimidazole and/or 4-vinylpyridine. The invention further relates to a method of producing said sorbent and the use of the sorbent.
    Type: Grant
    Filed: March 26, 2014
    Date of Patent: October 30, 2018
    Assignee: Biotage AB
    Inventors: Ecevit Yilmaz, David Nivhede, Johan Billing, Markus Rudolfsson, Mats Leeman, Adam Senior
  • Patent number: 10092680
    Abstract: The present invention provides metal medical devices which are provided with sliding properties (lubricity), low protein adsorption properties and low cell adsorption properties and further in which these properties are prevented from deteriorating. The present invention relates to a metal medical device having a surface at least partially treated with a copolymer C of a polymerizable silane compound A and a polymerizable compound B that contains a functional group.
    Type: Grant
    Filed: August 18, 2015
    Date of Patent: October 9, 2018
    Inventors: Yasuhisa Minagawa, Takefumi Nakashita
  • Patent number: 9833539
    Abstract: The present invention discloses a ?-polylysine hydrogel and the preparation method and application of the as-described ?-polylysine hydrogel. The polylysine hydrogel is non-toxic to a recipient, and has biodegradability and biocompatibility. The wound tissue healing material prepared by the present invention can be used in wound tissue adhesion in an efficient, stable, safe manner.
    Type: Grant
    Filed: December 28, 2013
    Date of Patent: December 5, 2017
    Inventors: Hong Xu, Bo Chi, Rui Wang, Xiaohai Feng, Sha Li, Jinfeng Liang, Pingkai Ouyang
  • Patent number: 9827172
    Abstract: A dentifrice composition comprising an orally acceptable vehicle having distributed therein a water hydratable film flakes having a matrix comprised of a water soluble hydroxy alkyl cellulose polymer and a starch, and flaying entrained therein a constituent selected from therapeutic cosmetic and decorative materials.
    Type: Grant
    Filed: June 4, 2013
    Date of Patent: November 28, 2017
    Assignee: Colgate-Palmolive Company
    Inventors: Thomas J. Boyd, Guofeng Xu, M. Teresa R. Carale
  • Patent number: 9815240
    Abstract: The present invention relates to shape memory materials and to a method for controlling shape change in shape memory materials. In particular, the invention relates to a method and a system for forming complex shapes from shape memory materials and to shape memory materials having complex shapes.
    Type: Grant
    Filed: April 16, 2008
    Date of Patent: November 14, 2017
    Assignee: Smith & Nephew, Inc.
    Inventors: Horacio Montes de Oca Balderas, Malcolm Brown
  • Patent number: 9803080
    Abstract: A composite material in the form of a linear structure having a width, a length and a thickness, the composite material having a first component formed by a polymer and a second component formed by a reinforcing material, wherein the first component is a thermoplastic polymer selected from the group of biodegradable polymers and mixtures thereof, and the second component is platy wood particles. The composite material being formable at a temperature of about 50 to 70° C. and being capable of being employed as a blank for an orthopedic splint.
    Type: Grant
    Filed: December 16, 2013
    Date of Patent: October 31, 2017
    Assignee: ONBONE OY
    Inventor: Antti Pärssinen
  • Patent number: 9642932
    Abstract: A bone cement comprising an acrylic polymer mixture which is formulated to have a relatively high viscosity for a relatively long window, due to distributions of molecular weights and/or sizes of acrylic beads.
    Type: Grant
    Filed: September 11, 2007
    Date of Patent: May 9, 2017
    Assignee: DePuy Synthes Products, Inc.
    Inventors: Mordechay Beyar, Oren Globerman
  • Patent number: 9592244
    Abstract: The present disclosure relates to pharmaceutically acceptable complex formulae comprising complexes of Abiraterone acetate and pharmaceutically acceptable excipients, process for the preparation thereof and pharmaceutical compositions containing them. The complex formulae of the present disclosure have improved physicochemical properties which results in reduced food effect which allows significant dose reduction and the abandoning of the requirement of taking the drug on an empty stomach.
    Type: Grant
    Filed: July 28, 2016
    Date of Patent: March 14, 2017
    Assignee: Druggability Technologies IP Holdco Limited
    Inventors: Erzsébet Réka Angi, Tamás Jordán, Orsolya Basa-Dénes, Tamás Solymosi, Zsolt Ötvös, Hristos Glavinas, Genovéva Filipcsei
  • Patent number: 9498410
    Abstract: A dentifrice composition comprising an orally acceptable vehicle having distributed therein a water hydratable film flakes having a matrix comprised of a water soluble hydroxy alkyl cellulose polymer and a starch, and having entrained therein a constituent selected from therapeutic cosmetic and decorative materials.
    Type: Grant
    Filed: December 21, 2007
    Date of Patent: November 22, 2016
    Inventors: Thomas J. Boyd, Guofeng Xu, M. Teresa R. Carale, Beth Ann Boff
  • Patent number: 9427379
    Abstract: Provided are opaque materials exhibiting a good adhesive strength and a good color tone reproduction comparable with natural dental crowns as well as having a good operability. In addition, the opaque materials may exhibit a stain-resistance property in rebuilding-up a dental composition on the opaque materials in a cured form with a metal instrument. Further, the opaque materials may exhibit a good color tone reproduction comparable with natural dental crowns even if a dental membrane is thinly formed from the opaque metals. The dental membrane is formed from a first opaque layer and a second opaque layer, wherein the first opaque layer contains a filler of indefinite-shape particles and the second opaque layer contains a filler of spherical-shape particles, and wherein the first opaque layer is formed on a metal base and the second opaque layer is formed on the first opaque layer.
    Type: Grant
    Filed: March 24, 2014
    Date of Patent: August 30, 2016
    Inventors: Jun Uchida, Mitsuji Teramae, Shuhei Takahashi, Masanori Goto, Ryuichi Yoshimoto
  • Patent number: 9355242
    Abstract: Managing and accessing personal data is described. In one example, an apparatus has an application processor, a memory to store data, a receive and a transmit array coupled to the application processor to receive data to store in the memory and to transmit data stored in the memory through a wireless interface, and an inertial sensor to receive user commands to authorize the processor to receive and transmit data through the receive and transmit array.
    Type: Grant
    Filed: December 17, 2012
    Date of Patent: May 31, 2016
    Assignee: Intel Corporation
    Inventors: Sasikanth Manipatruni, Kelin J. Kuhn, Debendra Mallik, John C. Johnson
  • Patent number: 9351731
    Abstract: A staple cartridge for use with a surgical stapling apparatus includes a cartridge body including a tissue contacting surface defining a plurality of staple retaining slots, a staple disposed within each staple retaining slot of the cartridge body, and a substantially circular buttress. The buttress includes an inner portion, an outer portion, and a middle portion extending between the inner portion and the outer portion. At least one stiffened region joins the buttress to the tissue contacting surface of the cartridge body. The inner portion, the middle portion, the outer portion, and the at least one stiffened region are all formed from a common material.
    Type: Grant
    Filed: December 14, 2011
    Date of Patent: May 31, 2016
    Assignee: Covidien LP
    Inventors: Sally Carter, Gerald Hodgkinson, Richard P. Stevenson, Arthur Hislop, Ernest Aranyi, Jennifer Whiffen
  • Patent number: 9290623
    Abstract: A resist underlayer film that can be used as a hardmask. A resist underlayer film forming composition for lithography, includes: as a silane, a hydrolyzable silane, a hydrolysis product thereof, or a hydrolysis-condensation product thereof, wherein the hydrolyzable silane includes a hydrolyzable silane of Formula (1) or a hydrolyzable silane containing a combination of a hydrolyzable silane of Formula (1) with a hydrolyzable silane of Formula (2) in a content of less than 50% by mole in all silanes; Formula (1): R1aR2bSi(R3)4-(a+b) wherein R1 is an organic group containing Formula (1-1), Formula (1-2), or Formula (1-3): a is 1 and b is an integer of 0 to 2, where a+b is an integer of 1 to 3; Formula (2): R4aR5bSi(R6)4-(a+b) wherein, R4 is an organic group containing Formula (2-1), Formula (2-2), or Formula (2-3): a is 1 and b is an integer of 0 to 2, where a+b is an integer of 1 to 3.
    Type: Grant
    Filed: December 17, 2013
    Date of Patent: March 22, 2016
    Inventors: Yuta Kanno, Daisuke Sakuma, Kenji Takase, Makoto Nakajima, Shuhei Shigaki
  • Patent number: 9282962
    Abstract: A surgical stapler, or fastening instrument, may generally comprise a layer, such as a tissue thickness compensator, for example, releasably attached to a fastener cartridge and/or anvil by a flowable attachment portion. The flowable attachment portion may be indefinitely flowable. The flowable attachment portion may be flowable from the time that layer is installed to the fastener cartridge to the time in which the layer is implanted to patient tissue. The flowable attachment portion may comprise a pressure sensitive adhesive. The flowable attachment portion may comprise an adhesive laminate comprising a base layer comprising the tissue thickness compensator and an adhesive layer on at least a portion of a surface of the base layer comprising the pressure sensitive adhesive. Articles of manufacture comprising flowable attachment portion and methods of making and using the flowable attachment portion are also described.
    Type: Grant
    Filed: February 8, 2013
    Date of Patent: March 15, 2016
    Assignee: Ethicon Endo-Surgery, LLC
    Inventors: Katherine J. Schmid, Frederick E. Shelton, IV, Bret W. Smith
  • Patent number: 9193820
    Abstract: An antimicrobial polyurethane foam that is formed from: a multi-functional isocyanate component; an aqueous polyol component reactive with the multi-functional isocyanate component; an antimicrobial metallic compound; and a complexing agent. The complexing agent is used to form a stable blend of the antimicrobial metallic compound with the polyol component. Exemplary complexing agents include amine compounds, ammonium-containing compounds, and ammonia as well as combinations of these compounds. The antimicrobial metallic compound can be a silver, zinc, or copper compound. Desirably, the antimicrobial metallic compound is silver saccharinate. A process of making the antimicrobial polyurethane foam and stable blends used in the manufacture of the antimicrobial polyurethane foam are also disclosed.
    Type: Grant
    Filed: December 1, 2014
    Date of Patent: November 24, 2015
    Assignee: Avent, Inc.
    Inventors: Bhalchandra M. Karandikar, Bruce L. Gibbins
  • Patent number: 9062174
    Abstract: A single layer flexible foam includes the reaction product of an (A) isocyanate component and a (B) isocyanate-reactive component. The isocyanate component and the isocyanate-reactive component react in the presence of a (C) polyurethane gel. The polyurethane gel has a viscosity of from about 3,000 to about 12,000 cps at 25° C. and includes the reaction product of a polyol component and a second isocyanate component which react at an isocyanate index of from about 10 to about 70. The flexible foam also includes a plurality of agglomerated gel substrates that are formed from the polyurethane gel and that are dispersed in the flexible foam. The flexible foam is formed using a method including the steps of providing (A), providing (B), providing (C), and combining (C) with (A) and (B), such that (A) and (B) react in the presence of (C) to form the flexible foam.
    Type: Grant
    Filed: September 26, 2012
    Date of Patent: June 23, 2015
    Assignee: BASF SE
    Inventor: Theodore M. Smiecinski
  • Patent number: 9044288
    Abstract: Disclosed herein is a two part retraction system that can be inserted into the sulcus to form a semi-rigid porous elastomer releasing a hemostatic agent suitable for sulcus retraction such that a dental impression may be completed by a dental practitioner.
    Type: Grant
    Filed: December 19, 2013
    Date of Patent: June 2, 2015
    Assignee: DENTSPLY International Inc.
    Inventor: Christos Angeletakis
  • Publication number: 20150136150
    Abstract: Disclosed herein are methods and compositions of durable skin marking compositions that remains legible and visible on the skin after being treated with an aqueous, alcohol-based solution. The skin marking composition of the present invention includes a cyanoacrylate component, a solvent, and a colorant. The composition can further comprise one or more of viscosity modifiers/thickening agents, stabilizers, plasticizers, formaldehyde scavengers, polymerization accelerators, perfumes, adhesion promoters, and antibacterial, anti-fungal, anti-viral, or anti-microbial agents. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
    Type: Application
    Filed: November 5, 2012
    Publication date: May 21, 2015
    Applicant: OP-MARKS, INC.
    Inventors: Stephen Bruce Lober, Ian Askill
  • Publication number: 20150126615
    Abstract: Compositions of P4HB with high purity have been developed. The compositions are prepared by washing P4HB biomass prior to solvent extraction, and precipitating P4HB from solution. The same solvent is preferably used to wash the P4HB biomass, and as a non-solvent to precipitate the polymer from a P4HB solvent solution. The highly pure P4HB compositions are suitable for preparing implants. The implants may be used for the repair of soft and hard tissues.
    Type: Application
    Filed: October 31, 2014
    Publication date: May 7, 2015
    Inventors: David P. Martin, Simon F. Williams
  • Publication number: 20150119488
    Abstract: Disclosed herein are methods of making polymerizable resins containing a 1,3,5-hexahydro-1,3,5-triazine moiety and dental compositions comprising such novel hydrolytic stable, polymerizable resins derived from 1,3,5-triacryloyl-hexahydro-1,3,5-triazine (TAT).
    Type: Application
    Filed: October 30, 2014
    Publication date: April 30, 2015
    Inventor: Xiaoming JIN
  • Patent number: 9012415
    Abstract: This invention refers to photo-crosslinked hydrogel materials based in gellan gum suitable for tissue engineering and regenerative medicine applications or as drug delivery systems. Formulations of gellan gum with different degrees of acylation serve as precursor material for insertion of a polymerizable moiety. The materials are capable of free radical polymerization with a photo-initiator at mild temperatures and exposure to ultraviolet light, enabling control of reticulation and withstanding the encapsulation of human and animal cells and/or drugs, and any combination thereof. The physicochemical and biological properties can be adjusted by combining different formulations of gellan gum and reaction conditions.
    Type: Grant
    Filed: March 26, 2011
    Date of Patent: April 21, 2015
    Assignee: Stemmatters, Biotecnologia e Medicina Regenerativa S.A.
    Inventors: Joana Catarina Da Silva Correia, Joaquim Miguel Antunes De Oliveira, João Manuel Teixeira De Oliveira, Rui Pedro Amandi Romero De Sousa, Rui Luis Gonçalves Dos Reis
  • Patent number: 9005406
    Abstract: A method and a system for producing a change in a medium. The method places in a vicinity of the medium at least one energy modulation agent. The method applies an initiation energy to the medium. The initiation energy interacts with the energy modulation agent to directly or indirectly produce the change in the medium. The system includes an initiation energy source configured to apply an initiation energy to the medium to activate the energy modulation agent.
    Type: Grant
    Filed: January 16, 2014
    Date of Patent: April 14, 2015
    Assignee: Immunolight, LLC
    Inventor: Frederic A. Bourke, Jr.
  • Publication number: 20150093418
    Abstract: In accordance with the invention, with an eye swab for cleaning eyes of vertebrate animals, for example dog's eyes, is provided. The eye swab consists of a gel-like putty, wherein the gel-like putty is held together from a reversibly bonded, three-dimensional network formed of at least one natural or synthetic polymer, at least one cross-linking agent and glycerol.
    Type: Application
    Filed: September 11, 2014
    Publication date: April 2, 2015
    Inventors: Meinrad FLURY, Benjamin Tak Kwong LEE, Wing Shong Thierry CHAN, Chun Ho WONG, Yi Ming GAN
  • Patent number: 8993652
    Abstract: A dual-cure curable material kit comprising: (A) a radical-polymerizable monomer component; (B) a photopolymerization initiator component comprising (b1) an ?-diketone compound, (b2) an aliphatic tertiary amine compound having a tertiary amino group in which three saturated aliphatic groups are bonded to a nitrogen atom and one of the saturated aliphatic groups has an electron-withdrawing group as a substituent, and (b3) an s-triazine compound having a trihalomethyl group as a substituent, or a diaryliodonium salt compound; and a chemical polymerization initiator component (C) comprising (c1) an organic peroxide, and (c2) an N,N-di(hydroxyalkyl)-p-toluidine compound; which is packed separately at least in two packages so that the component (b2) and the component (b3) of the photopolymerization initiator component (B) are not packed together in a single package and the component (c1) and the component (c2) of the chemical polymerization initiator component (C) are not packed together in a single package.
    Type: Grant
    Filed: December 8, 2009
    Date of Patent: March 31, 2015
    Assignee: Tokuyama Dental Corporation
    Inventors: Kyoichi Fujinami, Kazuhiko Okishio
  • Patent number: 8993650
    Abstract: A dental coloring material composition comprising containing: (a) a polymerizable monomer and/or an oligomer, (b) a polymerization catalyst, and (c) a pigment and/or a dye, wherein a color tone thereof is a cyan color based on three subtractive primary colors, or a color tone thereof is a magenta color based on three subtractive primary colors, or a color tone thereof is a yellow color based on three subtractive primary colors, and a dental color material set using the dental coloring material compositions in combination.
    Type: Grant
    Filed: July 1, 2009
    Date of Patent: March 31, 2015
    Assignee: Kabushiki Kaisha Shofu
    Inventors: Jun Uchida, Yushin Okimoto, Mitsuji Teramae, Mitsuharu Mizuno
  • Patent number: 8968765
    Abstract: The present disclosure provides a brush polymer, including: a linear polymer main chain; and brush structural side chains, including: a hydrophobic molecular branch, and a hydrophilic molecular branch and/or an anti-biofilm/or an anti-microbial molecular branch, wherein the linear polymer main chain is conjugated to the side chains by covalent bonds formed between a hydroxyl group and a reactive functional group, wherein the reactive functional group includes: isocyanate, carboxyl, or epoxy. The present disclosure also provides a medical application of the brush polymer.
    Type: Grant
    Filed: August 27, 2012
    Date of Patent: March 3, 2015
    Assignee: Industrial Technology Research Institute
    Inventors: Jui-Hsiang Chen, Jean-Dean Yang, Yu-Hua Chen, Ting-Yu Shih, Chia-wei Hong, Chao-Chen Tien
  • Patent number: 8962037
    Abstract: The present invention discloses a method of manufacturing pure dicalcium phosphate ceramics or dicalcium phosphate/hydroxyapaite (HA) biphasic ceramics for medical applications in hard tissue areas to be used as implant materials. These ceramic implant materials are in granular form or in block form, and are prepared by using an acidic phosphate compound, a basic calcium phosphate compound comprising HA, and water. The dicalcium phosphate ceramic comprises either dicalcium phosphate dihydrate (CaHPO4.2H2O, DCPD) or dicalcium anhydrous (CaHPO4, DCPA). Wherein, when the acidic phosphate compound is provided in an amount stoichiometrically equal to or in excess relative to the basic calcium phosphate compound, a reaction product is the DCPD or DCPA ceramic; when the acidic phosphate compound is provided in the amount stoichiometrically less than the basic calcium phosphate compound, the reaction product is the DCPD/HA or DCPA/HA biphasic ceramic.
    Type: Grant
    Filed: February 8, 2011
    Date of Patent: February 24, 2015
    Assignee: Maxigen Biotech Inc.
    Inventors: Sung-Tsuen Liu, Sung-Ching Chen, Hui-Chun Lai, Wan-Ting Huang
  • Publication number: 20150038775
    Abstract: Disclosed are various embodiments of systems, devices, components and methods for improving acoustic coupling between a bone conduction hearing device (BCHD) and a patient's head or skull. Such systems, devices, components and methods include disposing a gel or paste between the BCHD and the patient's skin, hair and/or skull. The gel or paste improves the transmission of acoustic signals generated by a transducer in the BCHD to the patients head or skull by providing a more efficient and improved intermediary acoustic medium for the transmission of acoustic signals to the patient's head or skull.
    Type: Application
    Filed: October 16, 2014
    Publication date: February 5, 2015
    Applicant: Sophono, Inc.
    Inventor: Peter Ruppersberg
  • Publication number: 20150011673
    Abstract: Provided are: an organic/inorganic composite, and a manufacturing method therefor; and a dental material and bone substitute material manufactured using the organic/inorganic composite. The organic/inorganic composite includes: (A) 100 parts by mass of a thermoplastic resin containing as a main component at least one kind selected from a polyarylketone resin and a polysulfone resin; and (B) 60 to 300 parts by mass of an inorganic particle mixture dispersed in the thermoplastic resin, in which the inorganic particle mixture contains inorganic particles each having a particle diameter of from 200 to 700 nm at a content of 25 vol % or more, and inorganic particles each having a particle diameter of from 40 to 100 nm at a content of 10 vol % or more.
    Type: Application
    Filed: November 20, 2012
    Publication date: January 8, 2015
    Applicant: Tokuyama Dental Corporation
    Inventors: Jun-ichiro Yamagawa, Hiroshi Shimizu, Yongjin Li
  • Publication number: 20150005409
    Abstract: A stimuli-responsive material includes a stimuli-responsive polymer, fibers and water, wherein the fibers have a number average diameter of 1 to 900 nm and are present in the stimuli-responsive material in a dispersed state; and a medical material and an anti-adhesive material, each of which includes a stimuli-responsive material including a stimuli-responsive polymer, fibers and water, wherein the fibers have a number average diameter of 1 to 900 nm and are present in the stimuli-responsive material in a dispersed state.
    Type: Application
    Filed: January 29, 2013
    Publication date: January 1, 2015
    Inventors: Tomoyuki Horiguchi, Kosaku Takeuchi, Yoshihiro Naruse, Kazuhiro Tanahashi, Makito Yokoe, Kohei Yamashita
  • Patent number: 8920515
    Abstract: A graft prostheses (11), materials and method for implanting, transplanting, replacing, or repairing a part of a patient. The graft prosthesis includes a purified, collagen-based matrix structure removed from a submucosa tissue source. The submucosa tissue source is purified by disinfection and removal steps to deactivate and remove contaminants, thereby making the purified structure biocompatible and suitable for grafting on and/or in a patient.
    Type: Grant
    Filed: October 31, 2007
    Date of Patent: December 30, 2014
    Assignees: Cook Biotech Incorporated, Cook Medical Technologies LLC
    Inventors: William A. Cook, Michael C. Hiles, Thomas G. Kozma, Umesh H. Patel
  • Patent number: 8921448
    Abstract: A low toxicity, highly efficient transfection composition is described with an amphipathic compound containing at least one imidazole. The composition may be used in the process of transfecting nucleic acids into an animal cell.
    Type: Grant
    Filed: July 16, 2010
    Date of Patent: December 30, 2014
    Assignee: Mirus Bio LLC
    Inventors: Shannon E. Bruse, Laura K Juckem, Karen M Neder
  • Publication number: 20140378573
    Abstract: Since a medium having light propagation properties and sound propagation properties similar to those of human tissues is provided, reflection of light and an acoustic wave at a surface of a test portion is prevented, and accuracy control of a photoacoustic wave diagnostic apparatus is realized. A photoacoustic matching material is provided which includes a polyol, an inorganic oxide, and a pigment, the latter two being dispersable in the polyol, and in this photoacoustic matching material, a dispersed amount of the inorganic oxide to the polyol is in a range of 0.10 to 0.25 percent by weight, and a dispersed amount of the pigment to the polyol is in a range of 0.0001 to 0.0005 percent by weight.
    Type: Application
    Filed: September 12, 2014
    Publication date: December 25, 2014
    Inventors: Takahiro Suita, Takuji Oishi
  • Patent number: 8912247
    Abstract: Improved methods for preparing polyethylene glycol fumarate) are disclosed. Methods for chemically crosslinking or photocross-linking hydrophilic polyethylene glycol fumarate) with hydrophobic polymers such as poly(propylene fumarate) (PPF) and poly(caprolactone fumarate) (PCLF) to form various hydrogels (FIG. 1) with controllable hydrophilicity are also disclosed. The hydrogels are useful in the fabrication of injectable and in-situ hardening scaffolds for application in skeletal reconstruction. An injectable material including the hydrogels may be useful in controlled drug release.
    Type: Grant
    Filed: April 28, 2006
    Date of Patent: December 16, 2014
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Shanfeng Wang, Lichun Lu, Michael J. Yaszemski
  • Publication number: 20140364532
    Abstract: The invention relates to unique applications for the novel high melt flow, low viscosity, selectively hydrogenated styrene-butadiene-styrene (hSBS) or selectively hydrogenated controlled distribution styrene-butadiene/styrene-styrene (hSBSS) block copolymers, wherein the melt flow rate of said block copolymer is at least 100 g/10 min at 230° C. under 2.16 kg mass according to ASTM D1238. These block copolymers are novel and have the highest melt flow rate of any styrenic block copolymer also possessing high strength and elasticity. It has applications that prior to the present invention were not normally possible due to the normal low melt flow rate of styrenic block copolymers. The present invention also encompasses various fields of use such as a fiberglass hSBS or hSBSS reinforced mat, low viscosity hSBS or hSBSS coatings for industrial uses, hot melt adhesives prepared from hSBS or hSBSS blended with polyalpha-olefins, and elastic film, fiber, and nonwoven constructions using hSBS or hSBSS.
    Type: Application
    Filed: August 27, 2014
    Publication date: December 11, 2014
    Inventors: Donn Anthony DUBOIS, John E. FLOOD
  • Publication number: 20140350137
    Abstract: The present application relates to a radio opaque material and a method of producing the same. The material is a hybrid material comprising two phases, an inorganic phase comprising a radio opaque substance and a polymer phase.
    Type: Application
    Filed: December 20, 2012
    Publication date: November 27, 2014
    Inventors: Lisa Mellin, Karin Törne
  • Patent number: 8889760
    Abstract: Described herein is a degradable linking agent of formula Photo1-LG-Photo2, wherein Photo1 and Photo2 independently represent at least one photoreactive group and LG represents a linking group comprising one or more silicon atoms or one or more phosphorous atoms. The degradable linking agent includes a covalent linkage between at least one photoreactive group and the linking group, wherein the covalent linkage between at least one photoreactive group and the linking group is interrupted by at least one heteroatom. A method for coating a support surface with the degradable linking agent, coated support surfaces and medical devices are also described.
    Type: Grant
    Filed: March 29, 2011
    Date of Patent: November 18, 2014
    Assignee: SurModics, Inc.
    Inventors: Aleksey V. Kurdyumov, Dale G. Swan
  • Patent number: 8889758
    Abstract: The present invention relates to dental materials comprising liquid, nanoparticulate functionalized hydrophobic co-condensates of tetraalkyl silicates with functionalized trialkoxysilanes of the formula I P—(CH2)n—Si(OR)3 where P, R and n independently of one another have the following meanings: P=a polymerizable CH2?CH—, CH2?CH—O—, styryl, (meth)acrylic or (meth)acrylamide group or an SH group capable of polyaddition, R=methyl, ethyl or propyl and n=from 3 to 15, which can be prepared by co-condensation of tetraalkyl silicates with alkyltrialkoxysilanes functionalized in the ? position and subsequent end group functionalization with trimethylsilyl groups; The invention further relates to the use of the dental materials for filling composites, fixing cements or materials for coatings.
    Type: Grant
    Filed: March 27, 2007
    Date of Patent: November 18, 2014
    Assignee: Ivoclar Vivadent AG
    Inventors: Norbert Moszner, Volker Rheinberger, Simone Klapdohr, Urs Karl Fischer
  • Publication number: 20140336277
    Abstract: Radiopaque, iodinated, absorbable polyesters, polyester urethanes, and polyether-ester-urethanes with and without inorganic iodide micro-/nanoparticles dispersed or solubilized therein, and composite inorganic iodide micro-/nanoparticles in an absorbable polyester, polyester-urethane, polyester-ester, or polyether-ester urethane matrix are employed in medical devices and therapeutic compositions.
    Type: Application
    Filed: July 22, 2014
    Publication date: November 13, 2014
    Applicant: POLY-MED, INC.
    Inventors: Shalaby W. Shalaby, Kenneth David Gray
  • Publication number: 20140335031
    Abstract: A liquid composition including between 1 and 15 parts by weight of PEBA to 100 parts by weight of solvent, wherein: said solvent includes between 1 and 49% by volume of alcohol low in C1 to C4 and between 51 and 99% by volume of a cosolvent miscible with alcohol, in the total volume of solvent. Further, use of such a composition for producing water-resistant objects, such as coatings, films, varnishes, paints, in particular anti-graffiti coatings, seals, in particular sealing joints, personal protective equipment, gloves, flexible masks, condoms, and protective equipment for electronic or computer hardware.
    Type: Application
    Filed: January 4, 2013
    Publication date: November 13, 2014
    Inventors: Frédéric Malet, Marie-Ange Michel
  • Patent number: 8883876
    Abstract: The subject matter of the invention is a radically polymerizable dental material comprising at least two components. A first component of the dental material contains the salt of a CH-acidic compound, and an additional component contains an acid with acidity greater than that of the CH-acidic compound of the first component. Both components contain radically polymerizable monomers. When the two components are mixed, the acid of the second component converts the salt of the CH-acidic compound of the first component into a CH-acidic molecule, and the CH-acidic molecule triggers the radical polymerization of the monomers. In addition to the advantages of CH-acidic compounds in dental materials on the basis of a reactive resin, the invention achieves long-term storage stability as a result of an increase in the proportion of the reactive resin matrix in polymerizable dental materials.
    Type: Grant
    Filed: May 11, 2007
    Date of Patent: November 11, 2014
    Assignee: Muhlbauer Technology GmbH
    Inventor: Rainer Lueck
  • Patent number: 8871993
    Abstract: The present invention relates to a pressure sensitive adhesive composition for skin application. The adhesive composition comprises 10-50% (w/w) based on the total adhesive composition of a polar part; 10-50% (w/w) based on the total adhesive composition of an apolar part; and 0-60% (w/w) based on the total adhesive composition of hydrocolloid.
    Type: Grant
    Filed: June 17, 2011
    Date of Patent: October 28, 2014
    Assignee: Coloplast A/S
    Inventors: Hasse Buus, Tom Bjarnum Kongebo, Astrid Carlsen
  • Patent number: 8871828
    Abstract: Improved composition of a fixing cream, in particular for tooth prostheses, containing at least one oil and/or fat, preferably of a plant type, at least one water-soluble polymer selected from the group of cellulose derivatives, at least one alkyl vinyl ether/maleic acid anhydride copolymer, the fatty acid content of the plant oil or fat contained consisting of at least 20% by weight of unsaturated fatty acids.
    Type: Grant
    Filed: January 19, 2011
    Date of Patent: October 28, 2014
    Inventor: Jean Pierre Bogaert