Abstract: A pressure sensitive adhesive composition is provided that includes a pressure sensitive adhesive polymer. The polymer includes: at least one copolymerized monoethylenically unsaturated (meth)acrylic acid ester monomer, wherein the (meth)acrylic acid ester monomer, when homopolymerized, has a Tg of less than about 25° C.; at least one copolymerized monoethylenically unsaturated reinforcing monomer, wherein the reinforcing monomer, when homopolymerized, has a Tg of at least about 25° C.; covalently bonded quarternary ammonium functionality; and, optionally, at least one copolymerized monoethylenically unsaturated poly(alkylene oxide) monomer. The composition optionally further includes at least one nonreactive poly(alkylene oxide) polymer and/or at least one antimicrobial agent.

Abstract: A cyanoacrylate composition comprising (i) at least one lower cyanoacrylate monomer component selected from ethyl cyanoacrylate or methoxy ethylcyanoacrylate; (ii) at least one higher cyanoacrylate monomer component than in an amount greater than 12% by weight based on the total weight of the combination of the lower cyanoacrylate monomer and the higher cyanoacrylate monomer and (iii) a plasticizer. The higher cyanoacrylate monomer and the plasticizer are chosen from certain ones. The compositions cure to give flexible polymeric materials which are desirably also transparent.

Abstract: The present invention relates to novel hydrocolloid adhesive masses consisting of an adhesive mixture based on a low molecular polyisobutylene and a poly(styrene/olefin/styrene) block polymer, and of a cellulose derivative, with which an acrylate polymer with a glass transition temperature below ?20° C. is associated for the purpose of increasing the resistance to deterioration of the absorption capacity of said hydrocolloid adhesive mass after radiosterilization. The invention further relates to the use of these novel hydrocolloid adhesive masses for medical, dermatological or cosmetic purposes and particularly for the production of dressings for the treatment of blisters, exudative wounds, burns and superficial, deep, chronic or acute dermo-epidermal lesions.

Abstract: Crosslinked compositions formed from water-insoluble copolymers are disclosed. These compositions are copolymers having a bioresorbable region, a hydrophilic region and at least two cross-linkable functional groups per polymer chain. Crosslinking of these polymers can be effected in solution in organic solvents or in solvent-free systems. If crosslinking occurs in a humid environment, a hydrogel will form. If crosslinking occurs in a non-humid environment, a xerogel will form which will form a hydrogel when exposed to a humid environment and the resulting crosslinked materials form hydrogels when exposed to humid environments. These hydrogels are useful as components in medical devices such as implantable prostheses. In addition, such hydrogels are useful as delivery vehicles for therapeutic agents and as scaffolding for tissue engineering applications.

Abstract: The present invention relates to powdered, crosslinked polymer compositions, containing a) 55-99.9 wt.-% of at least one polymerized, ethylenically unsaturated, polymerizable monomer which contains acid groups neutralized to at least 25 mole-%, b) 0-40 wt.-% of polymerized, unsaturated monomers copolymerizable with a), c) 0.01-5.0 wt.-%, preferably 0.1-2.0 wt.-% of one or more crosslinking agents, d) 0-30 wt.-% of a water-soluble polymer, the weight amounts a) through d) being based on anhydrous polymer composition, and the sum of these components always being 100 wt.-%, which compositions can be obtained by continuous polymerization wherein at least one parameter biasing the polymerization is varied according to a recurring pattern. The present invention also relates to a process for their production and to their use.

Abstract: The present invention relates to a disposable human waste management devices such as faecal and urine management devices (10) which are provided with adhesives for attachment of the device to the skin. In particular the present invention relates to adhesives (20) that provide secure attachment and are pleasing to the skin upon application, yet cause no discomfort upon removal. In particular the present invention relates to skin attachment means which provide secure attachment under moist and wet skin conditions and which maintains adhesive peel strength even under exposure to excess water.

Abstract: Polymer nanocomposite implants with nanofillers and additives are described. The nanofillers described can be any composition with the preferred composition being those composing barium, bismuth, cerium, dysprosium, europium, gadolinium, hafnium, indium, lanthanum, neodymium, niobium, praseodymium, strontium, tantalum, tin, tungsten, ytterbium, yttrium, zinc, and zirconium. The additives can be of any composition with the preferred form being inorganic nanopowders comprising aluminum, calcium, gallium, iron, lithium, magnesium, silicon, sodium, strontium, titanium. Such nanocomposites are particularly useful as materials for biological use in applications such as drug delivery, biomed devices, bone or dental implants.

Abstract: A thermoplastic composition that includes from about 1% by weight to 25% by weight block copolymer having the formula (A-B)x where the A block includes polyvinylarene, the B block includes poly(monoalkenyl) and x is an integer of at least one, spherical superabsorbent particles comprising polyacrylate, and plasticizing oil, the composition exhibiting water gel time of no greater than 2 minutes, a viscosity of no greater than 100,000 centipoise and a wet tensile strength of at least 15 g/in2.

Abstract: This invention relates to a radiation-resistant acrylic adhesive composition with less reduction in the adhesion thereof upon irradiation with radiations, which composition comprises an acrylic polymer and a radiation-resistant agent, and a radiation-resistant adhesive product comprising the composition.

Abstract: The present invention is directed to pressure sensitive hydrocolloid adhesive compositions having probe tack of about 300-750 grams force, tensile strength of about 500-3500 grams/cm2 and saline absorbency of about 500-5000 grams/m2/24 hours.

Abstract: Featured are biodegradable polymers comprising repeat units derived from cyclic phosphate monomers and optionally further comprising repeat units derived from lactide or caprolactone monomers. Also featured are methods for preparing the biodegradable polymers of the invention and biodegradable polymer compositions comprising a biologically active substance and a biodegradable polymer. Additionally featured are articles and microspheres prepared from biodegradable polymers and polymer compositions of the invention. Further, methods for the controlled release of a biologically active substance using the biodegradable polymers of the invention are also described.

Abstract: Biodegradable, flowable or flexible polymer compositions are described comprising a polymer having the recurring monomeric units shown in formula I: wherein: each of R and R′ is independently straight or branched alkylene, either unsubstituted or substituted with one or more non-interfering substituents; L is a divalent cycloaliphatic group; R″ is selected from the group consisting of H, alkyl, alkoxy, aryl, aryloxy, heterocyclic or heterocycloxy; and n is 5 to 1,000, wherein said biodegradable polymer is biocompatible before and upon biodegradation. In one embodiment, one or more of R, R′ or R″ is a biologically active substance. Amorphous compositions containing a biologically active substance, in addition to the polymer, and methods for controllably releasing biologically active substances using the compositions, are also described.

Abstract: The adhesive agent composition of the present invention comprises from 50 to 90% by weight of an acrylic adhesive agent, 2.5 to 50% by weight of a polyhydric alcohol-containing liquid component, and 0.01 to 10% by weight of a salt of a mono- to tri-valence metal of an aliphatic acid that contains a hydrocarbon group of 8 to 18 carbon atoms. The adhesive agent composition shows good adhesion, cohesive force and permeability, and an adhesive drug composition having the above properties can be prepared by adding a drug (medicine, etc.) to the adhesive composition. An adhesive tape excellent in permeability or an adhesive tape preparation excellent in permeability and cutaneous absorption of the drug can be produced by coating a substrate with the adhesive agent composition or adhesive drug composition.

Abstract: The present invention relates to absorbent articles, typically for feminine protection, comprising a topsheet, a backsheet and an absorbent element positioned between the tospheet and the backsheet, said absorbent element comprising a fluid storage layer which comprises a liquid absorbent thermoplastic composition comprising a polymeric base material having particles of water-insoluble water-swellable absorbent material dispersed therein, the liquid absorbent thermoplastic composition being configured in a plurality of unattached spaced apart zones.

Abstract: A fluid-absorbing, composite material that is pressure sensitive adhesive and which is made of a mixture comprising a continuous phase formed from a pressure sensitive adhesive matrix, and a discontinuous phase substantially comprised of one or more natural or synthetically derived water soluble and/or water insoluble absorbents, characterised in that the continuous phase contains trans-polyoctenamer polymer, which material serves to elevate the shear strength of the composite. Because of its low melting point, compositions containing trans-polyoctenamer polymer are very easy to process. Formulations can be prepared that have only weakly adhesive properties, also formulations that are suitable as primary dressings for various hard-to-heal and chronic wounds. The pressure sensitive adhesive can also be combined with a non-adhesive, water impervious film, or other backing material, and can be used as the protective adhesive skin barrier component of ostomy pouches.

Abstract: The present invention relates to a disposable absorbent articles such as diapers and sanitary napkins which are provided with adhesives for attachment of the article to the skin. In particular the present invention relates to adhesives which provide secure attachment and are pleasing to the skin upon application, yet cause no discomfort upon removal. In particular the present invention relates to an adhesive which provide secure attachment under moist and wet skin conditions and which maintains adhesive peel strength even under exposure to excess water.

Abstract: Crosslinked polyacrylates obtained by crosslinking, induced by means of UV radiation, of a polymer mixture comprising a) polyacrylate copolymers of the following monomers a1) acrylic acid and/or acrylic esters of the following formula CH2═CH(R1)(COOR2), where R1═H or CH3 and R2 is an alkyl chain having 1-20 carbon atoms, at 70-99% by weight, based on component (a), a2) olefinically unsaturated monomers containing functional groups, at 0-15% by weight, based on component (a), a3) tert-butyl acrylate, at 1-15% by weight, based on component (a), and b) a photocationic initiator at 0.01-25% by weight, based on the overall polymer mixture.

Abstract: An adhesive material is used for connecting a protuberant electrode of an electronic component to a terminal electrode of a circuit board for carrying said electronic component through the adhesive material containing at least one curable resin and inorganic particles.

Abstract: A bioadhesive composition for use as a skin adhesive, the composition formed by polymerizing with cross-linking and/or entanglement an aqueous reaction mixture comprising effective amounts of at least one monomer dissolved or suspended therein and capable of forming a hydrogel on polymerization, optionally at least one cross-linking agent for the monomer, and water, said composition having an elastic modulus (G′) and a viscous modulus (G″), wherein the degree of polymerization and/or the degree of cross-linking and/or entanglement are selected to control the skin adhesion properties of the bioadhesive composition having regard to the rate of change of tan delta (G″÷G″) against frequency in a diagnostic portion of the frequency range 0.01 to 300 rad/s, typically the lower end of the said frequency range below about 100 rad/s.

Abstract: A medical pressure sensitive adhesive based on polyacrylates and neutral polyamine salts is characterized in that it has a pressure-sensitive adhesive matrix of two polymer components A and B, with polymer component A being a polyacrylate pressure-sensitive adhesive containing carboxyl groups, the carboxyl groups of which are neutralised; the polymer component B being a neutral polyamine salt obtained by reacting a polyacrylate copolymer containing amino groups with an acid, with the polymer component B being dispersed in the polymer component A, and the two components forming a two-phase system.

Abstract: An orthopedic casting material comprising a substrate impregnated with a water-curable resin comprising an aromatic polyisocyanate and a polyol, wherein the free NCO level of said prepolymer is from about 6% to about 10%. Preferably the free NCO level is from about 7% to about 8%. Preferably the polyol has a molecular weight of at least 2,000, and a hydroxyl number of from about 28 to about 56, preferably from about 35 to about 40. The casting material may be packaged as a kit with a casting aid comprising a substrate impregnated with a lubricating material.

Abstract: Crosslinked compositions formed from water-insoluble copolymers are disclosed. These compositions are copolymers having a bioresorbable region, a hydrophilic region and at least two cross-linkable functional groups per polymer chain. Crosslinking of these polymers can be effected in solution in organic solvents or in solvent-free systems. If crosslinking occurs in a humid environment, a hydrogel will form. If crosslinking occurs in a non-humid environment, a xerogel will form which will form a hydrogel when exposed to a humid environment and the resulting crosslinked materials form hydrogels when exposed to humid environments. These hydrogels are useful as components in medical devices such as implantable prostheses. In addition, such hydrogels are useful as delivery vehicles for therapeutic agents and as scaffolding for tissue engineering applications.

Abstract: A pressure sensitive adhesive composition is provided that includes a pressure sensitive adhesive polymer. The polymer includes: at least one copolymerized monoethylenically unsaturated (meth)acrylic acid ester monomer, wherein the (meth)acrylic acid ester monomer, when homopolymerized, has a Tg of less than about 25° C.; at least one copolymerized monoethylenically unsaturated reinforcing monomer, wherein the reinforcing monomer, when homopolymerized, has a Tg of at least about 25° C.; covalently bonded quarternary ammonium functionality; and, optionally, at least one copolymerized monoethylenically unsaturated poly(alkylene oxide) monomer. The composition optionally further includes at least one nonreactive poly(alkylene oxide) polymer and/or at least one antimicrobial agent.

Abstract: Ophthalmic lenses, such as corneal contact lenses, include a lens body made of a composition including a lens body made of a composition including a first crosslinked polymer material which is water swellable, and a second polymeric material, other than the first material, selected from water soluble polymeric materials, water swellable polymeric materials and mixtures thereof. The second material is physically immobilized by the first material. Such lenses provide increased water retention and/or increased water content and/or increased modulus and/or reduced friction which increases lens wearer comfort. Compositions and methods for providing such lenses and compositions are also provided.

Abstract: The absorbent in accordance with the present invention is limited in at least two of the following requirements: ventilation resistance, absorbency under no load and/or under load, weight mean particle diameter, and water-soluble components. The absorbent exhibits a 24 g/g or more absorbency under a 2.0 kPa load and a 50 kPa·sec/m or less ventilation resistance under a 4.9 kPa load in a wet state. The absorbing product in accordance with the present invention is based on this absorbent and therefore exhibits improved ventilating properties when worn and relatively little wet back of water-based liquids, providing a further improved sense of comfort to users wearing the absorbing product.

Abstract: A method of sterilizing a polymerizable monomeric adhesive composition includes: providing a polymerizable monomeric adhesive composition in a container, the polymerizable monomeric adhesive composition including a polymerizable 1,1-disubstituted ethylene monomer and at least one stabilizer; holding the composition in the container for a pre-determined amount of time, which is sufficient to inhibit or eliminate polymerization of the monomer during or immediately after sterilization, before sterilizing the composition; and sterilizing the polymerizable monomeric adhesive composition inside the container.

Abstract: Disclosed are hyaluronate-containing hydrogels having angiogenic and vascularizing activity and pre-gel blends for preparing the hydrogels. The hydrogels contain a cross-linked matrix of a non-angiogenic hyaluronate and a derivatized polysaccharide material, in which cross-linking is effected by free-radical polymerization. Kits for preparing the hydrogels are also disclosed.

Abstract: An adhesive composition that contains a preservative is particularly useful as a medical adhesive and can include alkyl cyanoacrylate monomers. The preservative is preferably soluble in the monomer. The composition may optionally be sterilized by placing a mixture of a polymerizable adhesive monomer and a preservative in a container, sealing the container, and sterilizing the mixture and the container.

Abstract: Disclosed are methods for sterilizing cyanoacrylate prepolymer compositions under visible light irradiation conditions wherein the prepolymer remains in polymerizable form after sterilization.

Abstract: The present invention concerns novel methods for enhancing the mechanical performance of tissue adhesives and sealants which comprises employing a primer molecule in association with a tissue adhesive or sealant, wherein the primer molecule serves to enhance the strength of the interface between the tissue and the adhesive matrix. The primer molecules described herein function to interact with a protein present in the tissue, thereby altering its characteristics to make it more amenable to bonding with the adhesive matrix. Primer molecules may be applied to the tissue independently from the tissue adhesive or sealant or may be mixed with the tissue adhesive or sealant prior to application to the tissue.

Abstract: Disclosed are methods for vascular reconstruction of diseased, non-aneurysmal arteries.

Abstract: The present invention is generally directed to adhesive compositions comprising selected ratios of crystalline and amorphous polymers. In some versions of the invention, polymers capable of existing in different configurations (e.g., a polymer such as polypropylene which can exist in an atactic, syndiotactic. or isotactic configuration) are used to prepare adhesives of the present invention. As an example, a selected amount of isotactic polypropylene is blended with a selected amount of atactic polypropylene to prepare an adhesive composition having one or more performance properties (e.g., bond strength) that are superior to the performance properties of a conventional hot-melt adhesive. The adhesive compositions of the present invention are suitable for use in the preparation of laminated disposable absorbent products.

Abstract: A pressure sensitive adhesive composition suitable for medical purposes comprising a rubbery elastomeric base and water soluble or water swellable hydrocolloids, where the adhesive composition includes a substantially homogeneous mixture of 15-60% of one or more rubbery components, 10-60% of a mixture of hydrocolloids that includes a cellulose derivative, amidated pectin, and potato starch, 0-50% of one or more tackifier resins, 0-15% cohesive strengthening agent, 0-10% of a plasticizer and 0-5% pigment. The adhesive shows at least as good properties as state of the art adhesives comprising gelatine with respect to resistance to biological fluids, adhesion to skin, and coherence.

Abstract: Crosslinked compositions formed from water-insoluble copolymers are disclosed. These compositions are copolymers having a bioresorbable region, a hydrophilic region and at least two cross-linkable functional groups per polymer chain. Crosslinking of these polymers can be effected in solution in organic solvents or in solvent-free systems. If crosslinking occurs in a humid environment, a hydrogel will form. If crosslinking occurs in a non-humid environment, a xerogel will form which will form a hydrogel when exposed to a humid environment and the resulting crosslinked materials form hydrogels when exposed to humid environments. These hydrogels are useful as components in medical devices such as implantable prostheses. In addition, such hydrogels are useful as delivery vehicles for therapeutic agents and as scaffolding for tissue engineering applications.

Abstract: The present invention relates to thermoplastic compositions for making a liquid impermeable moisture vapor permeable layer by coating the composition onto a substrate. The thermoplastic compositions comprise preferred thermoplastic polymers and suitable hydrophilic plasticisers to adjust the viscosity of the composition at the process conditions. The layers made from the thermoplastic compositions of the present invention can find a variety of applications wherein moisture vapour permeability is desirable, such as within absorbent articles for example diapers, sanitary napkins, panty liners and incontinence products, and also protective bedding covers, protective clothing and the like.

Abstract: The present invention relates to a composition comprising a thermoplastic component and at least one superabsorbent polymer, methods of use for such composition, and articles comprising such composition. The composition may be formed into a film layer or applied to an article with various hot melt adhesive application techniques. The composition is useful for a variety of end-uses, particularly for use in disposable absorbent articles such as disposable diapers, feminine napkins and medical dressings.

Abstract: The present invention relates to using certain block copolymer based hot melt adhesive compositions for the assembly of disposable absorbent articles such as disposable diapers wherein the adhesive is in contact with an oil-based skin care ingredient, and the resulting disposable absorbent article. The adhesive is particularly useful for adhesively bonding elastic to nonwoven, and exhibits good stress resistance in the presence of lotion.

Abstract: An adhesive composition includes a polymerizable adhesive monomer, at least one vapor phase stabilizer, and at least one liquid phase stabilizer. The combination of at least one vapor phase stabilizer and at least one liquid phase stabilizer provides superior stabilization and shelf-life for the monomer composition. The stabilized adhesive composition provides superior performance and shelf-life and can be sterilized without significant polymerization of the monomer.

Abstract: Structured polyacrylates obtainable by crosslinking, induced by UV irradiation, of a polymer mixture comprising the following components: a) polyacrylate copolymers of the following monomers a1) acrylic acid and/or acrylic esters of the following formula CH2=CH(R1)(COOR2),  where R1=H or CH3 and R2 is an alkyl chain having 1-20 carbon atoms, at 70-99% by weight, based on component (a), a2) olefinically unsaturated monomers containing functional groups, at 0-15% by weight, based on component (a), a3) tert-butyl acrylate, at 1-15% by weight, based on component (a), and b) a photocationic initiator at 0.01-25% by weight, based on the overall polymer mixture, the structuring of the polyacrylates comprising the presence in the polyacrylates of regions of high crosslinking alongside regions of low crosslinking and/or noncrosslinked regions.

Abstract: A mouldable mass of a hypoallergenic, substantially non-memory putty-like adhesive for use in connection with an ostomy appliance, said mass comprising: a) 1 to 20% by weight of a block copolymer having a major content of di-block copolymer, b) to 5 to 60% by weight of a tackifying liquid constituent, and c) 1 to 10% by weight of a waxy constituent has superior quality with respect to cohesion, gives the mass resistance against erosion and at the same time enables the removal of the mass as an integrated unit without leaving residues at the skin.

Abstract: The present invention relates to thermoplastic compositions for making a liquid impermeable moisture vapor permeable layer by coating the composition onto a substrate. The thermoplastic compositions comprise preferred thermoplastic polymers and suitable hydrophilic plasticizers that also enhance the moisture vapor permeability of films or layers made from the thermoplastic compositions. The layers made from the thermoplastic compositions of the present invention can find a variety of applications wherein moisture vapor permeability is desirable, such as within absorbent articles for example diapers, sanitary napkins, panty liners and incontinence products, and also protective bedding covers, protective clothing and the like.

Abstract: The present invention relates to shape-formed three dimensional articles which are moisture vapour permeable and liquid impermeable and comprise liquid impermeable formed structures having an enhanced moisture vapour permeability and comprising thermoplastic compositions having a higher processability. The shape-formed three dimensional articles of the present invention can find a variety of applications wherein moisture vapour permeability combined with liquid imperviousness are desirable.

Abstract: A pressure sensitive adhesive composition suitable for medical purposes comprising a rubbery elastomeric base and one or more water soluble or water swellable hydrocolloids, the adhesive composition comprising a substantially homogeneous mixture of 35-50% of one or more polybutenes, 5-20% of one or more styrene copolymers, and 20-60% of one or more hydrocolloids has very good properties as an adhesive for ostomy appliances.

Abstract: A pressure sensitive hot melt adhesive composition which comprises a high molecular weight rubber and less than about 60 parts by weight of a liquid diluent, and has a G′ of less than about 15×104 dynes/cm2 at 10 rad/s at 25° C. is useful for adhesive skin application (e.g., surgical tape), including transdermal drug delivery applications.

Abstract: v mouldable mass of a hypoallergenic, substantially non-memory putty-like adhesive for use in connection with an ostomy appliance, said mass comprising: a) 1 to 20% by weight of a blockcopolymer having a major content of di-block copolymer, b) 5 to 60% by weight of a tackifying liquid constituent, and c) 1 to 10 % weight of a waxy constituent has superior quality with respect to cohesion, gives the mass resistance against erosion and at the same time enables the removal of the mass as an integrated unit without leaving residues at the skin.

Abstract: A pressure sensitive adhesive composition suitable for medical purposes comprising a rubbery elastomeric base and one or more water soluble or water swellable hydrocolloids, the adhesive composition comprising a substantially homogeneous mixture of 15-60% of a butyl rubber, 15-60% of one or more tackifier resins, 1-10% of a tackifying liquid constituent, 20-60% of one or more hydrocolloids and 0-3% of a pigment shows very good properties as an adhesive for ostomy appliances.

Abstract: Superabsorbent polymers having a slow rate of absorption, and a process for their preparation. The superabsorbent polymer has a slow rate of absorption, is crosslinked with a covalent crosslinking agent and the metal of a polyvalent metal salt and has an Absorption Rate Index of at least about 5 minutes. Such polymers are prepared by contacting a substrate water-swellable, water-insoluble polymer particle with a polyvalent metal salt solution under conditions such that there is formed a polymer having an Absorption Rate Index of at least about 5 minutes.

Abstract: Crosslinked compositions formed from a water-insoluble copolymer are disclosed. These compositions are copolymers having a bioresorbable region, a hydrophilic region and at least two crosslinkable functional groups per polymer chain. These compositions are able to form hydrogels in aqueous environments when crosslinked. These hydrogels are good sealants for implantable prostheses when in contact with an aqueous environment. In addition, such hydrogels can be used as delivery vehicles for therapeutic agents.

Abstract: Biodegradable, flowable or flexible polymer compositions are described comprising a polymer having the recurring monomeric units shown in formula I: wherein: each of R and R′ is independently straight or branched alkylene, either unsubstituted or substituted with one or more non-interfering substituents; L is a divalent cycloaliphatic group; R″ is selected from the group consisting of H, alkyl, alkoxy, aryl, aryloxy, heterocyclic or heterocycloxy; and n is 5 to 1,000, wherein said biodegradable polymer is biocompatible before and upon biodegradation. In one embodiment, one or more of R, R′ or R″ is a biologically active substance. Amorphous compositions containing a biologically active substance, in addition to the polymer, and methods for controllably releasing biologically active substances using the compositions, are also described.

Abstract: Anti-microbic copolymers and derivatives thereof are used in methods for controlling odor in hygienic articles. The copolymers comprise at least two different ethylenically unsaturated monomers.