Abstract: A generic polymeric agent for releasing 5-aminosalicylic acid or its salts is disclosed which comprises a nonabsorbable pharmacologically acceptable organic polymer backbone containing aromatic rings to which are covalently bonded via azo bonds a plurality of salicylic acid or salicylate salt groups. The azo bonds attach to the salicylates' 5-position carbon. The polymers undergo bacterial cleavage in the mammalian lower bowel to release 5-aminosalicylic acid and/or its salts.
Type:
Grant
Filed:
December 20, 1978
Date of Patent:
February 26, 1980
Assignee:
Dynapol
Inventors:
Thomas M. Parkinson, Joseph P. Brown, Robert E. Wingard, Jr.
Abstract: A graft copolymer of an episulfide and the reaction product of a polyalkylenimine and a lower ketone is water-soluble or water-dispersible. The copolymer is made by adding an episulfide to the polyalkylenimine dissolved in a lower ketone and heating below the boiling point of the solvent. The resulting graft copolymer is a corrosion inhibitor.
Abstract: A novel process for the polymerization of aziridine compounds is disclosed. The polymerization process includes mixing an aziridine compound with a polymerization initiator having the formula: ##STR1## where R.sup.1 is an alkyl radical of 1 to 18 C atoms,R.sup.2 is an alkyl radical of 1 to 18 C atoms or a phenyl alkyl radical of 7 to 18 C atoms, wherein said alkyl radicals may contain an ester group and/or ether group, R.sup.3 and R.sup.4 are hydrogen, an alkyl radical of 1 to 18 C atoms, and/or an aryl radical which can be substituted with a chloro, nitro or alkoxy group, whereby the alkyl radicals of R.sup.3 and R.sup.4 together or in combination with B can form a cycloaliphatic or heterocyclic ring, B is an electron attracting radical, and A.sup..crclbar. is a non-nucleophilic anion.Polyimines are quickly formed at ambient temperature.
Abstract: The method of binding a water-soluble, direct dye to paper is improved by using as a binder the reaction product of a polyalkylene polyamine and a quaternary ammonium salt. For example, the direct dye Intralite.RTM. Yellow 2RLSW manufactured by Crompton & Knowles bound to paper toweling by the reaction product of a polyethylenimine having a number average molecular weight of about 40,000 and 3-chloro-2-hydroxypropyl trimethylammonium chloride demonstrates improved bleed resistance under alkaline conditions than when bound to similar paper toweling by conventional binders, such as polyethylenimine or other cationic, nitrogen-containing polymers.
Abstract: Novel polymers having a linear backbone which is free from both branching and cross-linking, comprising either tertiary or quaternized nitrogen atoms linked to each other through ethylene groups. These polymers are useful as antimicrobials, flocculating agents, antistatic agents, electroconductive agents for coating paper, chelating agents and bile acid binding agents, as well as in similar applications where their high charge to weight ratio and fully accessible nitrogen atoms can be employed. The polymers are obtained by the polymerization of an oxazoline, hydrolysis or direct reduction, nitrogen substitution, and optional quaternization of the resulting polymer.
Type:
Grant
Filed:
September 29, 1977
Date of Patent:
July 17, 1979
Assignee:
Merck & Co., Inc.
Inventors:
Arthur F. Wagner, Nathaniel Grier, Tsung-Ying Shen
Abstract: Water-soluble, crosslinked nitrogen-containing condensation products, the viscosity of which, in aqueous solution, increases with increasing temperature, are obtained by reacting a chlorohydrin-ether of the formula ##STR1## where x is from 50 to 250, y is from 20 to 100, the ratio x:y is from 6.1:1 to 1:15 and n is from 0.5 to 5, with ethyleneimine in the weight ratio of from 1:10.1 to 1:0.8; the condensation products are added to aqueous systems, e.g. polymer solutions and polymer dispersions, to improve the viscosity characteristics.
Type:
Grant
Filed:
August 3, 1977
Date of Patent:
December 5, 1978
Assignee:
BASF Aktiengesellschaft
Inventors:
Werner Streit, Rolf Fikentscher, Karl Gans, Gerhard Welzel
Abstract: Amine containing polymeric microspheres such as polyvinyl pyridine are complexed with metal salts or acids containing metals such as gold, platinum or iron. After reduction with sodium borohydride, the salt is reduced to finely divided free metal or metal oxides, useful as catalysts. Microspheres containing covalent bonding sites can be used for labeling or separating proteins.
Abstract: A light sensitive material suitable for coating onto a support to produce a light sensitive plate for use in, for example, the manufacture of a printing plate comprises groups of the formula: ##STR1## attached to carbon atoms of a polymer, wherein --Z-- is --o-- or ##STR2## or ##STR3## wherein R.sub.5 represents a hydrogen atom or an alkyl group; R is an aromatic radical; a is zero or unity; R.sub.1, R.sub.2 and R.sub.3 are hydrogen atoms, halogen atoms, cyano groups, or specified aliphatic or aromatic groups; X is a deactivating group; R.sub.4 is a hydrogen atom, a carboxyl group, a cyano group or a specified aliphatic or aromatic group; and Ph is a phenyl group. The material may be produced by reacting a polymer containing epoxide groups, hydroxyl groups, or primary and/or secondary amino groups with the halosulphonyl group of a compound having the formula: ##STR4## wherein R, R.sub.1, R.sub.2 R.sub.3, and a having the above meanings, wherein X has the above meaning or is a halosulphonyl group and R.sub.
Abstract: A composition and method for electrodepositing ductile, bright, well leveled copper deposits from an aqueous acidic copper plating bath having dissolved therein from about 0.04 to about 1000 milligrams per liter of a poly (alkanol quaternary ammonium salt) formed as the reaction product of a polyalkanolamine with an alkylating or quaternization agent. The polyalkanolamine constituent typically is formed as the reaction product of a polyalkylenimine (e.g. polyethylenimine) with an alkylene oxide.
Type:
Grant
Filed:
May 4, 1977
Date of Patent:
August 29, 1978
Assignee:
Oxy Metal Industries Corporation
Inventors:
Hans-Gerhard Creutz, deceased, Roy W. Herr