Abstract: A packaged garment includes a garment and a sealed bag. The garment has a torso portion, a sleeve portion connected to the torso portion, and a leg portion connected to the torso portion. The garment has an outer surface and an inner surface opposite the outer surface. The sealed bag contains the garment with the sleeve portion folded onto the torso portion and the leg portion folded onto the torso portion. The garment is manipulated so that the inner surface of the torso portion faces outward and the torso portion forms an inner space containing the sleeve portion and the leg portion.

Abstract: A simplified paracetamol solution for an injectable and ready-to-use preparation is only composed of paracetamol, bi-distilled water and a buffer agent, the formulation having a maximal paracetamol concentration of 1 g/100 ml, a pH between 5.5 and 6.5 and an oxygen content inferior to 0.2 ppm. A method for preparing and packaging such a solution and a device for packaging such a solution are also disclosed.

Abstract: A method and an apparatus for sterilizing packaging material for use in packaging for protein containing products, such as food products or medical drugs. The packaging material is sterilized by irradiating it using a beam of ionizing radiation, such as an electron beam or a beam of gamma rays. Afterwards, the packaging material is processed in such a manner that protein reactive substances or compounds formed in the packaging material during the irradiation step are at least partly removed or rendered inreactive with respect to proteins. The processing step may advantageously be performed by heating the packaging material. Preferably, the processing step involves accelerating diffusion from the packaging material of protein reactive substances or compounds. Since the protein reactive substances or compounds are removed or rendered inreactive with respect to proteins, degradation of the product which is later stored in the packaging material is considerably reduced.

Abstract: This application is directed toward an improved method of synthesizing cationic siloxane prepolymers as well as a specific cationic siloxane prepolymer having improved compatibility with monofunctional siloxanyl methacrylate monomers and medical devices containing the cationic siloxane prepolymer.

Abstract: A method of transferring at least one object, sterilised and packed into a bag, into a clean room, where the bag is connected with an inner liner connecting the clean room with an outer room and on this is opened at an area open towards the inner liner so that a tube-like connection, closed towards the outer room, is formed between the interior of the bag and the inner liner, through which the at least one object is transferred into the clean room.

Abstract: A process for aseptic packaging of sterile liquids in flexible containers including a pre-chamber pressurized with a sterilized inert fluid that is injected through an auxiliary line and flows out to activate a sterile barrier such as to allow complete asepsis of the packaging process. A pressing device compresses the film to form a seal against the outer surface of the feed tube that introduces sterile liquid into the aseptic packaging chamber.

Abstract: The invention relates to a process for producing polyethylene aseptic squeezable pouches. The invention also covers said pouches and their use for medical packaging applications.

Abstract: Apparatus for molding and filling a device having a body defining an opening in communication with an interior chamber for receiving a substance therein, and a closure including a penetrable and resealable portion for sealing the opening and substance received in the device. A mold includes within the aseptic chamber plural mold cavities shaped to form the closure and body, and substantially sterile surfaces extending about and contiguous to the peripheries of the mold cavities. An assembly device including end-of-arm tooling having an engaging portion engageable with each of the body and closure is movable relative to the mold to engage and de-mold the substantially sterile closures and bodies from the mold cavities. Flexible barriers are coupled to the mold and the tool to substantially prevent the passage of contaminants from the molding machine and tool therethrough.

Abstract: The invention provides a method for single-step terminal sterilization process for bio-active heparin coatings on materials and biomaterials containing heparin used in medical devices, such as catheters, tissue engineering scaffolds, or drug delivery carrier materials. This may include any medical device or implantable that could benefit from improved antithrombotic and biocompatible heparin surfaces. Other relevant device examples may include heparin or a heparin derivative coated stents to reduce clotting and restenosis, dental or ophthalmological implants. These materials may comprise additional polymeric compositions such as polyethyleneimine, dextran sulfate or their modified forms. These polymers together with heparin coatings may be applied to other substrate of medical devices such as metal, ceramics or biologically derived materials.

Abstract: A package (599) with three layers allows sterilization of the package contents, provides a separate area for a scavenger and minimizes the oxygen transmission rate for the package and has, in one embodiment, a third layer (330) with a first section (336) of breathable polymeric material, a second section (334) of substantially non-breathable polymeric material and a third section (332) of breathable polymeric material which is positioned between a first layer (512) of substantially non-breathable polymeric material and a second layer (514) of substantially non-breathable polymeric material. The first layer (512) and the second layer (514) are fixed together to define a non-breathable pouch (516); and the third layer (330) is fixed to the first layer (512) and the second layer (514) and divides the non-breathable pouch (516) into a first compartment (592) and a second compartment (594).

Abstract: A method for filling dual-chamber systems in pre-sterilizable carrier systems includes providing at least one washed, siliconized and sterilized dual-chamber system with respectively one separating element separating the two chambers from one another in a magazine, which accommodates the at least one dual-chamber system. The magazine is arranged in a container sealed with a closure element. The method additionally includes feeding the container into a clean room; opening the container and filling a first chamber of the at least one dual-chamber system; closing the first chamber with a gas-permeable closure element; and freeze drying the solution contained in the first chamber. The method further includes closing the first chamber with a closure element; filling a second chamber of the at least one dual-chamber system; closing the second chamber; and discharging the container from the clean room.

Abstract: A method for filling dual-chamber systems in pre-sterilizable carrier systems includes providing at least one washed, siliconized and sterilized dual-chamber system in a magazine. The dual-chamber system includes respective separating elements separating the two chambers from each other. The magazine accommodates at least one dual-chamber system and is arranged in a container that is sealed with a closing element. The method additionally includes introducing the container into a clean room; opening the container and filling a first chamber of the at least one dual-chamber system; and closing the first chamber. The method further includes filling a second chamber of the at least one dual-chamber system; closing the second chamber; and removing the system from the clean room.

Abstract: A packaging system and method for use with a fiber, and in particular, an optical fiber of the type typically used for surgical procedures, in order to protect the fiber during storage and shipping and also allow the fiber to be easily dispensed in a controlled manner by an end user.

Abstract: A method and apparatus for packaging a medical device includes a package assembly that defines a multi-chambered interior. The interior chambers include a primary and a secondary chamber. A partition, which has a gas permeable vent, separates the primary chamber from the secondary chamber. The package is constructed from a variety of materials that provide the interior with a long term, low humidity, sterile environment.

Abstract: A container with a corresponding bottle neck having a capsule inside of which a substance is placed that is to be released into the bottle contents. This invention avoids having to sterilize the contents again after the container has been aseptically filled, even though the substance in the capsule often does not endure these temperatures. Thus, this invention provides a method with the following steps: a) aseptic filling of the plastic bottle; b) welding a first membrane onto the container neck; c) placing the substance, which is to be released into the plastic bottle, on the first membrane that is already welded on; d) covering the substance, which is to be released, by a second membrane and welding the second membrane to the first membrane. Lastly, a closure with a secured tamper-evident layer is placed over the capsule and onto the bottle neck.

Abstract: A testing unit and a method of testing a sterilization packaging unit for microbial contamination of sterilized objects after they have been sterilized are disclosed. The testing unit includes a dry matrix for accommodating a nutrient medium and a receptacle containing a liquid. By applying the liquid onto the matrix, the matrix is provided with a nutrient medium. In the method, the testing unit is inserted into the sterilization packaging unit which is sterilized and stored. At a desired point in time, the receptacle is opened in order to produce the nutrient medium in the matrix. After a possible multiplication of microbes on the matrix, an observation of microbes takes place. The invention also relates to a sterilization packaging unit which has a rigid outer casing and is suitable for the application of the method.

Abstract: Apparatus for molding and filling a device having a body defining an opening in communication with an interior chamber for receiving a substance therein, and a closure including a penetrable and resealable portion for sealing the opening and substance received in the device. A mold includes within the aseptic chamber plural mold cavities shaped to form the closure and body, and substantially sterile surfaces extending about and contiguous to the peripheries of the mold cavities. An assembly device including end-of-arm tooling having an engaging portion engageable with each of the body and closure is movable relative to the mold to engage and de-mold the substantially sterile closures and bodies from the mold cavities. Flexible barriers are coupled to the mold and the tool to substantially prevent the passage of contaminants from the molding machine and tool therethrough.

Abstract: The invention relates to a process for manufacturing and hot-filling a PET container comprising the following steps: a) providing a PET preform capable of being blow molded; b) blow molding the preform in the cavity of a mold so as to form a container; c) removing the container from the mold cavity; d) filling the container with a liquid, the temperature of which is above 80° C.; e) sealing the container in a leaktight fashion; f) sterilizing and cooling the container; and g) shrinking the container, characterized in that: in step a) a PET preform composed of a copolymer based on terephthalic acid is used; in step a), at least one part of the preform is at a temperature greater than or equal to 110° C.; the temperature of the mold used in step b) is less than or equal to 65° C.; and during step g) the container is heated for a duration between 1 and 5 seconds at a temperature between 600 and 1000° C.

Abstract: A sterile device immersed in a sterile buffer and a method for providing same. The sterile device may be a medical device such as a biosensor having a biomolecule as a sensing element such as, for example, a glucose oxidase enzyme. The buffer may be a bicarbonate solution. Both the device and the buffer may be packaged and stored over long term while maintaining sterilization. The sterilization method may comprise a combination of gaseous, liquid and light sterilization.

Abstract: A process for making a medicinal vial in which a vial and a closure are moulded in parallel in respective vial and closure moulds, then the closure and vial are automatically assembled together, all in a sterile environment. An apparatus for performing this process is also provided. By the process and apparatus of the invention sealed vials with a sterile interior may be made.

Abstract: A process for producing a catheter comprises mixing ETFE and PTFE in a mass ratio of from 99:1 to 45:55 to form a mixture, forming the mixture into a tubular body, forming a reinforcement layer and a resin layer on said tubular body to form a catheter configured to be positioned in a lumen of a living body, sealingly packaging the catheter to produce a packaged catheter, and sterilizing the packaged catheter with electron beam irradiation.

Abstract: Disclosed is a container and method for filling same. The container includes a thermally resealable portion that is fusible in response to thermal energy, and a container body having a sealed empty chamber in fluid communication with the resealable portion for receiving therein a substance. The container also includes a base, a mid-portion, and an upper portion axially spaced from the base on an opposite side of the mid-portion relative to the base. Each of the base and upper portion define a laterally-extending dimension greater than a maximum laterally-extending dimension of the mid-portion. The method of filling the container includes penetrating the resealable portion with an injection member and introducing a substance into the chamber, withdrawing the injection member while engaging the base of the body to substantially prevent axial movement of the body, and applying thermal energy to the resealable portion to thermally fuse the penetrated region thereof.

Abstract: In one embodiment, there is provided a method for producing a sterilized and pyrogen-free bag for storing fluids. The method includes providing a bag comprised of polymeric film and heating the bag to at least approximately 253 degrees Celsius for at least approximately 30 minutes for sterilization and pyrogen removal. The polymeric film is a polymer selected from the group of poly(oxy-1,4-phenylene-oxy -1,4-phenylene-carbonyl-1,4-phenylene) (PEEK); polytetrafluoroethylene (PTFE); a perfluoroalkoxy (PFA) polymer; poly(tetrafluoroethylene-co-perfluoromethyl vinyl ether) (MFA); polyperfluoro(ethylene-co-propylene)(FEP); poly(ethylene-alt-chlorotrifluoroethylene) (ECTFE); poly(ethylene-co-tetrafluoroethylene) (ETFE); poly(vinylidene fluoride) (PDVF); tetrafluoroethylene-co-hexafluoropropylene-co-vinylidene fluoride terpolymer (THV); poly(bisphenol A-co-4-nitrophthalic anhydride-co-1,3-phenylenediamine) (PEI); poly(4-methyl-1-pentene) (PMP); and suitable mixtures thereof.

Abstract: Process for the continuous vacuum prepacking of food products that can be pasteurized and/or sterilized in a container closed by a cover that has no hooking element and is equipped with an elastic seal maintained by a forced vacuum, and the cover is opened by a vacuum-breaking system. During the placing under vacuum, the cover is kept apart from the previously filled container, superheated vapor is injected at a temperature, a flow rate and/or a time that allow the sterilization of the cover and the head space of the container by expelling air and incondensable products, in particular oxygen; the container is then pressed against the cover or vice versa, and a jet of cold water is sent onto the cover, which causes rapid cooling of the cover, the immediate condensation of the vapor phase in the head space of the container that allows the placing under deep vacuum.

Abstract: A method involving the hot fill of foods in packaging containers constructed from a paperboard laminate comprises the food being filled in the packaging container with at least one component at a temperature of at least 80°, but below 100°, whereafter the packaging containers are closed and sealed and the packaging containers with their food contents are thereafter held hot during a predetermined period of time by contact with a heat holding medium at a temperature of at least 80°, but below 100°. The heat holding medium is present substantially in gas and/or vapour phase. An apparatus involving the hot fill of foods is also disclosed.

Abstract: The invention relates to a package intended for thermal treatment comprising a fiber-based packaging material treated with a hydrophobic size and comprising one or more layers for reduced water penetration outside and/or inside the fiber substrate. The package of the invention is characterized by the fiber substrate being treated with a combination of a wet-strength size, a hydrophobic size and an aluminum and/or calcium compound for increased heat resistance of the packaging material, and in that the ratio of hydrophobic size to the aluminium and/or calcium compound is 1:1-1:10.

Abstract: The invention relates to a device and a method for producing containers, such as e.g. bottles, in which different types of bottles are produced. Alternative treatment methods are used depending on the type of bottle to be produced. For example, a cooling treatment is carried out when producing bottles for carbonated beverages and a sterilisation treatment is carried out when producing bottles for non-carbonated beverages.

Abstract: The invention relates to a composite card/plastics package comprising a package main body (8) which is provided with a longitudinal seam (6) and having a folded and welded package floor (18) which is provided at one end (16) of the package main body (8), and to a method and apparatus for producing it, in the case of which package the object of specifying a composite card/plastics package which is also suitable for non-liquid products and can moreover be stacked satisfactorily is achieved by arranging at the top end (11) of the package main body (8) a ledge (10) which extends round it and fastening a lid (14/L) to the ledge (10) in such a way that the lid (14/L) is able to be pulled off.

Abstract: A package for enclosing volatile corrosion inhibiting materials includes a first enclosure barrier being fabricated from one or more gas-impermeable materials and defining a first enclosed space. The package further includes a substrate having one or more volatile corrosion inhibitor materials disposed thereon, with the substrate being disposed within the first enclosed space. In some embodiments, a second enclosure barrier being fabricated from a gas-permeable, solid particle-impermeable material is disposed in the first enclosed space, and defines a second enclosed space inside of the first enclosed space. In such embodiments, the substrate is preferably disposed within the second enclosed space.

Abstract: The present invention relates to a method of packaging and a packaging system for treated stents which minimise the level of exposure of the stents to oxygen, moisture and light. The package comprises two compartments, the compartments being in communication with each other via a breathable membrane.

Abstract: The invention refers to a device (1) and method for sterilizing partly formed packages (6) in a packaging machine. The device (1) comprises an inner chamber (2) and an outer chamber (3), the inner chamber (2) being provided with a sterilization unit (5). Further, it comprises a carrier unit (10), comprising a separating member (11) and a package carrying member (12), which is being adapted to rotate between a first position in which the package carrying member (12) is located in the outer chamber (3), and in which the separating member (11) separates the inner chamber (2) from the outer chamber (3), and a second position in which the carrier unit (10) has rotated a package (6) into the inner chamber (2) and in which the separating member (11) separates the inner chamber (2) from the outer chamber (3).

Abstract: Disclosed are biomedical devices having a hydrophilic coating on a portion of a surface thereof, the biomedical device comprising: (a) a biomedical device obtained from a polymerization product of a monomeric mixture comprising (i) a polymerizable monomer containing a boronic acid moiety and an electron withdrawing moiety; and (ii) a biomedical device-forming comonomer; and (b) a hydrophilic reactive polymer having complementary reactive functionalities along the polymer chain, wherein the complementary reactive functionalities along the polymer chain of the hydrophilic reactive polymer of (b) bind with the boronic acid moieties of the biomedical device of (a), thereby producing a biocompatible coating which can be removed and re-applied to restore the surface properties of the biomedical device to substantially as-new condition. Methods for treating the biomedical device are also disclosed.

Abstract: Disclosed are surface modified biomedical devices having a coating on a surface thereof, the coating comprising an inner layer comprising a polymer comprising monomeric units derived from an ethylenically unsaturated monomer containing a boronic acid moiety, and an outer layer comprising a hydrophilic hydrolyzed reactive polymer comprising monomeric units derived from an ethylenically unsaturated containing monomer having hydrolyzable reactive functionalities.

Abstract: Packaging systems for storing ophthalmic devices such as contact lenses and to methods for packaging such ophthalmic devices with solutions to improve the comfort of the lenses during wear are disclosed. A packaging system includes an ophthalmic device stored in an aqueous packaging solution comprising a brush copolymer comprising (a) monomeric units derived from an ethylenically unsaturated monomer containing one or more boronic acid moieties; and (b) monomeric units derived from an ethylenically unsaturated-containing hydrophilic macromonomer.

Abstract: A packaging arrangement (1) for bottles (12) of small volume, having a first packaging element (2) and a second packaging element (3), wherein each of the first and the second packaging elements (2, 3) has at least two depressions (4, 4?) spaced apart from each other and formed in a dimensionably stable manner, whose openings are surrounded by strips (10, 10?) with substantially level surfaces, by means of which the packaging elements (2, 3) are connected with each other in a manner sealed against fluids and releasably. The depressions (4, 4?) are equipped with spacing ribs (5, 5?), which are distributed over the circumference, which fix the bottles and the closures in place.

Abstract: The present invention relates to highly cross-linked UHMWPE, which is possessed of an improved oxidation resistance, as well as a method for making the same. The UHMWPE material of the current invention is combined with an anti-oxidant compound or a free-radical scavenger prior to formation. Once the UHMWPE with the added material has been formed and treated with gamma or electron beam irradiation, it shows an improved wear resistance and also a good resistance to oxidation. Such a material, is particularly interesting for the field of making replacement joint implants.

Abstract: The invention relates to a soft hydrogel contact lens, especially a silicone hydrogel contact lens, which has a capability of delivering a hydrophobic comfort agent into the eye of a wearer. The hydrophobic comfort agent includes without limitation a monoglyceride, a diglyceride, a triglyceride, a glycolipid, a glyceroglycolipid, a sphingolipid, a sphingo-glycolipid, a phospholipid, a fatty acid, a fatty alcohol, a hydrocarbon having a C12-C28 chain in length, a mineral oil, a silicone oil, or a mixture thereof. It can be released from the soft hydrogel contact lens into the eye of a wearer when being worn so as to strengthen and stabilize the tear film lipid layer and alleviate the dryness of the eye.

Abstract: An apparatus for transporting objects and in particular containers, having a first conveyor which transports the objects along a specified transport path (P), including a sterile room, within which the objects are transported, and including a second conveyor which follows on from the first conveyor. According to the invention, the first conveyor is positioned completely inside of the sterile room and the second conveyor is positioned completely outside of the sterile room, wherein both the first conveyor and the second conveyor are preferably positioned in a specified transitional area (B) along the transport path (P).

Abstract: The invention comprises a novel apparatus for delivering a nutritive substance comprising a container body having a base at one end thereof, an upper portion adapted for removable receipt of a closure, the upper portion defining an opening therein, and a chamber defined by the container body, the chamber being in fluid communication with the upper portion opening. A laminate seal having at least two layers is bonded across the upper portion opening and is adapted to provide an airtight seal across the opening. A nutritive substance is bonded to at least one layer of the laminate seal. The container additionally comprises a closure removably coupled to the upper portion. The closure comprises a cutting portion which is adapted to pierce the laminate seal, thereby releasing the nutritive substance into the container contents.

Abstract: The present invention relates to a method for the disinfection, partial disinfection or sterilization of a product by means of UV radiation. A product is enclosed with a UV permeable packaging material made of polyhydroxycarboxylic acid and subsequently disinfecting, partially disinfecting or sterilizing in the packaged state by means of irradiation with UV radiation.

Abstract: One aspect is a method of tattoo aftercare including preparing a cover assembly for application over a newly-created tattoo. A film is applied over the tattoo and the film is left in place over the tattoo for at least 12 hours.

Abstract: The present application relates to a method and apparatus for preparing and filling packages including pouches and containers, such as pouches and containers for food stuff. The abstract of the disclosure is submitted herewith as required by 37 C.F.R. §1.72(b). As stated in 37 C.F.R. §1.72(b): A brief abstract of the technical disclosure in the specification must commence on a separate sheet, preferably following the claims, under the heading “Abstract of the Disclosure.” The purpose of the abstract is to enable the Patent and Trademark Office and the public generally to determine quickly from a cursory inspection the nature and gist of the technical disclosure. The abstract shall not be used for interpreting the scope of the claims. Therefore, any statements made relating to the abstract are not intended to limit the claims in any manner and should not be interpreted as limiting the claims in any manner.

Abstract: The present invention relates to methods for making highly crystalline polymeric material, for example, highly crystalline cross-linked and not cross-linked ultra-high molecular weight polyethylene (UHMWPE). The invention also provides methods of making additive-doped highly crystalline polymeric material using high pressure and high temperature crystallization processes, medical implants made thereof, and materials used therein.

Abstract: Cup-shaped containers can be turned over and transferred with good stability from a sterilization-washing zone to the filling-sealing zone inside an aseptic chamber, and admixture of odor or microorganisms is prevented. The first conveyor 2 for conveying the cup-shaped container 38 in an inverted state and a second conveyor 3 for conveying the container in an upright state downstream of the first conveyor 2 are disposed in series in substantially the same plane inside a continuous aseptic chamber 1. A container supply device, a container sterilization device, and a container washing device are disposed successively along the first conveyor 2. A contents filling device 40, a lid material sealing device 41, and a device for discharging the sealed cup-shaped container are installed successively along the second conveyor 3. Sterilization and washing are performed in an inverted state, while conveying the container with the first conveyor 2.

Abstract: A stopper and container body are molded in the same molding machine. An assembly device, such as a pick and place robot, transfers the stopper from one mold cavity into the opening in the container body located within another mold cavity, or vice versa, to assemble the stopper and container body. Then, the assembled container body and stopper are removed from the molding machine and transported to a needle filling and laser resealing station for filling and laser resealing. A laminar flow source directs a substantially laminar flow of air or sterile gas over the mold surfaces, stoppers and container bodies, and assembly device, to prevent contamination during assembly.

Abstract: The present invention refers to a non-collapsible and non-foldable container for lyophilization of a product, said container comprising: a) a plastic tray comprising a bottom wall, a continuous peripheral side wall defining an opening, and a continuous circumferential rim which is outwardly bulged; b) a top wall for completely covering said opening, which top wall is comprising a membrane which membrane is vapour-permeable and provides a bacterial barrier; c) a removable impermeable snap-on lid for completely covering said top wall and said membrane. The container of the present invention is used for lyophilization of products and is easy to handle and provides a suitable shape for heat transfer during the lyophilization process. Further, the inventive container provides means for easy handling of opening and closing the membrane area before starting the lyophilization process, and also provides means for easy and reliable sealing after the lyophilization process, thereby protecting the membrane.

Abstract: An aseptic filling device for filling carbonate beverages capable of decreasing the size of the clean booth, facilitating maintenance around the filling valve, and reliably sterilizing the interior of gas piping is provided. The aseptic filling device includes a plurality of filling valves, a fluid rotary joint, a filling fluid tank, a fluid surface level sensor, a fluid flow adjustment valve, a container gripper, a plurality of exhaust conduits, an exhaust conduit on/off valve, a plurality of counter gas conduits, a counter gas conduit on/off valve, a rotary joint, an ascetic gas conduit, a flow meter, and a sterilizing filter, wherein rotary conveyed containers contact at least one of the filling valves and are sealed by a sealing member. Filling is performed under a gas pressure, for example, carbon dioxide gas pressure, and a sterilizing filter for sterilizing the gas is mounted on a gas pipe connecting the rotary joint and the filling fluid tank.

Abstract: Methods of packaging a medical device to orient at least a portion of the medical device and a medical device packaging assembly are provided. A method includes providing an elongate holder having a lumen extending through at least a portion of the holder and providing the medical device including an elongate shaft where the shaft includes a first cross-sectional area having a rotational orientation and a second cross-sectional area having a second rotational orientation. The method further includes aligning the first and second areas so that the first and second rotational orientations are aligned along a longitudinal region of the shaft and inserting at least a portion of the medical device into the lumen of the holder Radial rotation of the first area with respect to the second area is substantially prevented.

Abstract: The present invention relates to a closure for filling and sealing receptacles containing medicinal fluids, a method for filling a receptacle with a medicinal fluid and sealing the receptacle. The closure used in the method comprises a mounting piece that may be attached to the receptacle and a connector piece that may be connected to a connector piece of a filling device. A closure body is arranged between the mounting piece and the connector piece, in which a closure piece for sealing the closure sits. The closure piece may be slid between a position sealing the closure and a position which opens the closure. The closure is sealed tight with a removable protective cap. The present method is characterized in that with the protective cap removed the receptacle is filled through the closure in a clean room, whereupon after filling, the closure is sealed by pressing the closure piece into the closure.

Abstract: A packaging system for hydrating sterile devices without comprising the integrity of the sterilization. The packaging system may include an enclosure for enclosing a device requiring hydration, a container containing a hydrate, a base located within the interior of the enclosure and an activating member located within the interior of the enclosure. The container and the device may be located within a receptacle. The receptacle may rest on the base and the activating member may be affixed on top of the receptacle. A force may be exerted on an exterior portion of the enclosure such that the activating member pushes on the receptacle and crushes or ruptures the container. The hydrate located within the container is then released to the device, thereby hydrating the device without breaking the seal of the enclosure. The sterilized environment is therefore maintained and the device is hydrated.