Ethers Patents (Class 536/111)
  • Patent number: 9708416
    Abstract: Biodegradable microspheres having a diameter of 10-2000 ?m having cross-linked hydrolysed starch onto which at least one type of ligand has been coupled via a carboxylic ester bond. The ligand shall be an endogenous, charged molecule with a molecular mass of less than 1000 Da having at least one additional carboxylic acid function in addition to the one utilised for coupling the ligand to the microsphere and/or at least one amine function. On average 0.05-1.5 ligands are coupled to each glucose moiety in the hydrolysed starch.
    Type: Grant
    Filed: November 17, 2010
    Date of Patent: July 18, 2017
    Assignee: Magle AB
    Inventors: Malin Malmsjo, Eddie Thordarson, Sten Peter Apell, Peter Fyhr
  • Patent number: 9687501
    Abstract: A modified starch material is arranged for biocompatible hemostasis, biocompatible adhesion prevention, tissue healing promotion, absorbable surgical wound sealing and tissue bonding, when applied as a biocompatible modified starch to the tissue of animals. The modified starch material produces hemostasis, reduces bleeding of the wound, extravasation of blood and tissue exudation, preserves the wound surface or the wound in relative wetness or dryness, inhibits the growth of bacteria and inflammatory response, minimizes tissue inflammation, and relieves patient pain. Any excess modified starch not involved in hemostatic activity is readily dissolved and rinsed away through saline irrigation during operation. After treatment of surgical wounds, combat wounds, trauma and emergency wounds, the modified starch hemostatic material is rapidly absorbed by the body without the complications associated with gauze and bandage removal.
    Type: Grant
    Filed: May 14, 2013
    Date of Patent: June 27, 2017
    Inventors: Xin Ji, Cheng Xing, Xueshen Shi, Jianping Chen
  • Patent number: 8895533
    Abstract: The invention relates to a compound, comprising a) a first starch derivative selected from the group consisting of hydroxyalkyl starch, carboxyl alkyl starch, ester starch and arbitrary mixtures thereof, wherein the starch derivative has a mean relative molar mass Mw1 and a degree of molar substitution MS1, and b) a second starch derivative selected from the group consisting of hydroxyalkyl starch, carboxyl alkyl starch, ester starch and arbitrary mixtures thereof, having a mean relative molar mass Mw2 and a degree of molar substitution MS2, characterized in that Mw1 is greater than Mw2 (Mw1>Mw2) and MS2 is greater than MS1 (MS2>MS1).
    Type: Grant
    Filed: December 6, 2010
    Date of Patent: November 25, 2014
    Assignee: B. Braun Melsungen AG
    Inventors: Bernd Meier, Iris Theresia Jankowiak-Meier, Nele Meier, Clara Meier
  • Publication number: 20140186626
    Abstract: The present invention provides a modified starch, preparation method and use of the same, also provides a drilling fluid comprising the modified starch which contains bi-substituted starch structural units and tri-substituted starch structural units, wherein, the tri-substituted starch structural units are represented by the following formula (1), the bi-substituted starch structural units are the structural units represented by the following formula (2) and/or the structural units represented by the following formula (3), and the total content of the bi-substituted starch structural units and tri-substituted starch structural units accounts for 20 wt % or more of the modified starch, preferably 20-30 wt %, the weight-average molecular weight of the etherified starch is 50,000-600,000, preferably 80,000-580,000, wherein, R1, R2, and R3 are C1-C5 alkylene respectively, and M1, M2, and M3 are H, alkali metal element, or alkaline earth metal element respectively.
    Type: Application
    Filed: September 19, 2013
    Publication date: July 3, 2014
    Applicants: SINOPEC RESEARCH INSTITUTE OF PETROLEUM ENGINEERING, CHINA PETROLEUM & CHEMICAL CORPORATION
    Inventors: Zhifa WANG, Zhi Yang, Yongxue Lin, Xiaohua Yang, Jiang Xu, Long Chai, Zhoujun Li, Guo Zhang, Yang Xu, Haibo Wang, Yong Kong
  • Publication number: 20140128594
    Abstract: A method for manufacturing a modified hydroxyethyl starch carrying a heptonic acid residue on at least one of its termini is disclosed. Within this method, the following steps are carried out: a) dissolving hydroxyethyl starch in water, b) adjusting the pH value to a value of 8.0 to 10.0, c) adding a cyanide compound to the hydroxyethyl starch solution, heating the solution to a temperature of 80 to 99° C. and keeping it at this temperature for a first time period, and d) adjusting the pH value to a value of 2.0 to 4.0, bringing the solution to a temperature of 50 to 90° C. and keeping it at this temperature for a second time period.
    Type: Application
    Filed: June 21, 2012
    Publication date: May 8, 2014
    Applicant: SERUMWERK BERNBURG AG
    Inventors: Werner Zimmermann, Jan Lukowczyk
  • Publication number: 20140073779
    Abstract: The present invention relates to a hydroxyalkyl starch conjugate and a method for preparing the same, said hydroxyalkyl starch conjugate comprising a hydroxyalkyl starch derivative and a cytotoxic agent, the cytotoxic agent comprising at least one secondary hydroxyl group, wherein the hydroxyalkyl starch is linked via said secondary hydroxyl group to the cytotoxic agent. The conjugate according to the present invention has a structure according to the following formula HAS?(-L-M)n wherein M is a residue of the cytotoxic agent, L is a linking moiety, HAS? is the residue of the hydroxyalkyl starch derivative, and n is greater than or equal to 1, and wherein the hydroxyalkyl starch derivative has a mean molecular weight (MW) above the renal threshold.
    Type: Application
    Filed: July 11, 2011
    Publication date: March 13, 2014
    Applicant: Fresenius Kabi Deutschland GmbH
    Inventors: Helmut Knoller, Dominik Heckmann, Frank Hacket, Norbert Zander, Frank Nocken, Saswata Lahiri, Nitin Gupta, Sunil Sanghani, Azim Abul, Hemant Kumar Singh, Sandeep Grewal, Sandeep Kaur
  • Publication number: 20140073778
    Abstract: The present invention relates to hydroxyalkyl starch conjugates, a method for preparing the same, the hydroxyalkyl starch conjugate comprising a hydroxyalkyl starch derivative and a cytotoxic agent and the cytotoxic agent comprising at least one tertiary hydroxyl group, wherein the hydroxyalkyl starch is linked via said tertiary hydroxyl group to the cytotoxic agent. The conjugates according to the present invention have a structure according to the following formula HAS?(-L-M)n wherein M is a residue of the cytotoxic agent, L is a linking moiety, HAS? is the residue of the hydroxyalkyl starch derivative, and n is greater than or equal to 1, and wherein the hydroxyalkyl starch derivative has a mean molecular weight (MW) above the renal threshold.
    Type: Application
    Filed: July 11, 2011
    Publication date: March 13, 2014
    Applicant: Fresenius Kabi Deutschland GmbH
    Inventors: Helmut Knoller, Dominik Heckmann, Frank Hacket, Norbert Zander, Frank Nocken
  • Publication number: 20130260461
    Abstract: The present invention provides a mammalian stem cell suspension containing mammalian stem cells and at least one polysaccharide such as trehalose, and the like; a mammalian stem cell aggregation inhibitor containing polysaccharide such as trehalose, and the like; a method of suppressing aggregation of mammalian stem cells, containing suspending the mammalian stem cells in an aqueous physiological solution containing polysaccharide; an inhibitor of a decrease in the survival rate of mammalian stem cells containing polysaccharide such as trehalose and the like; a method of suppressing a decrease in the survival rate of mammalian stem cells, containing suspending the mammalian stem cells in an aqueous physiological solution containing polysaccharides, and the like.
    Type: Application
    Filed: November 9, 2011
    Publication date: October 3, 2013
    Applicants: JICHI MEDICAL UNIVERSITY, OTSUKA PHARMACEUTICAL FACTORY, INC.
    Inventors: Eiji Kobayashi, Tamaki Wada, Yasutaka Fujita, Norihiro Yoshinaga, Masako Doi, Yasuhiro Fujimoto, Takumi Teratani
  • Publication number: 20130251996
    Abstract: A modified starch material is arranged for biocompatible hemostasis, biocompatible adhesion prevention, tissue healing promotion, absorbable surgical wound sealing and tissue bonding, when applied as a biocompatible modified starch to the tissue of animals. The modified starch material produces hemostasis, reduces bleeding of the wound, extravasation of blood and tissue exudation, preserves the wound surface or the wound in relative wetness or dryness, inhibits the growth of bacteria and inflammatory response, minimizes tissue inflammation, and relieves patient pain. Any excess modified starch not involved in hemostatic activity is readily dissolved and rinsed away through saline irrigation during operation. After treatment of surgical wounds, combat wounds, trauma and emergency wounds, the modified starch hemostatic material is rapidly absorbed by the body without the complications associated with gauze and bandage removal.
    Type: Application
    Filed: May 14, 2013
    Publication date: September 26, 2013
    Inventors: Xin JI, Cheng Xing, Xueshen Shi, Jianping Chen
  • Publication number: 20130225803
    Abstract: The present invention relates to a method for preparing hydroxyalkyl starch. The method for preparing hydroxyalkyl starch comprises the steps of hydrolyzing starch, reducing the hydrolyzed starch, and substituting the reduced starch with hydroxyalkyl group in a dry process.
    Type: Application
    Filed: November 23, 2011
    Publication date: August 29, 2013
    Applicant: SAMYANG GENEX CORPORATION
    Inventors: Pil Nam Hong, Chang Heon Koh
  • Publication number: 20130196949
    Abstract: The present invention relates to hydroxyalkyl starch or a pharmaceutical preparation thereof for the treatment of cancer, tumor or tumor associated diseases, especially by effectively reducing tumor growth rate and inhibiting tumor growth and wherein the hydroxyalkyl starch has a mean molecular weight (MW) above 20 and below 1300 kDa and a molar substitution (MS) in the range of from 0.1 to 1.5, wherein the alkylation may be an ethylation, propylation or butylation or mixes thereof; and wherein the alkyl may be further substituted.
    Type: Application
    Filed: January 30, 2013
    Publication date: August 1, 2013
    Applicant: Fresenius Kabi Deutschland GmbH
    Inventor: Fresenius Kabi Deutschland GmbH
  • Publication number: 20130197212
    Abstract: The present invention relates to hydroxyalkyl starch or a pharmaceutical preparation thereof for the treatment of head and neck cancer, especially by effectively reducing tumor growth rate and inhibiting tumor growth and wherein the hydroxyalkyl starch has a mean molecular weight (MW) above 20 and below 1300 kDa and a molar substitution (MS) in the range of from 0.1 to 1.5, wherein the alkylation may be an ethylation, propylation or butylation or mixes thereof; and wherein the alkyl may be further substituted.
    Type: Application
    Filed: January 30, 2013
    Publication date: August 1, 2013
    Applicant: Fresenius Kabi Deutschland GmbH
    Inventor: Fresenius Kabi Deutschland GmbH
  • Publication number: 20130197211
    Abstract: The present invention relates to hydroxyalkyl starch or a pharmaceutical preparation thereof for the treatment of cancer, tumor or tumor associated diseases, especially by effectively reducing tumor growth rate and inhibiting tumor growth and wherein the hydroxyalkyl starch has a mean molecular weight (MW) above 20 and below 1300 kDa and a molar substitution (MS) in the range of from 0.1 to 1.5, wherein the alkylation may be an ethylation, propylation or butylation or mixes thereof; and wherein the alkyl may be further substituted.
    Type: Application
    Filed: January 30, 2013
    Publication date: August 1, 2013
    Applicant: Fresenius Kabi Deutschland GmbH
    Inventor: Fresenius Kabi Deutschland GmbH
  • Publication number: 20130184454
    Abstract: The present invention relates to hydroxyalkyl starch conjugates, a method for preparing the same, the hydroxyalkyl starch conjugate comprising a hydroxyalkyl starch derivative and a cytotoxic agent and the cytotoxic agent comprising at least one tertiary hydroxyl group, wherein the hydroxyalkyl starch is linked via said tertiary hydroxyl group to the cytotoxic agent. The conjugates according to the present invention have a structure according to the following formula HAS?(-L-M)n wherein M is a residue of the cytotoxic agent, L is a linking moiety, HAS? is the residue of the hydroxyalkyl starch derivative, and n is greater than or equal to 1, and wherein the hydroxyalkyl starch derivative has a mean molecular weight (MW) above the renal threshold.
    Type: Application
    Filed: July 11, 2011
    Publication date: July 18, 2013
    Applicant: Fresenius Kabi Deutschland GmbH
    Inventors: Helmut Knoller, Dominik Heckmann, Frank Hacket, Norbert Zander, Frank Nocken
  • Publication number: 20130184455
    Abstract: The present invention relates to a hydroxyalkyl starch conjugate and a method for preparing the same, said hydroxyalkyl starch conjugate comprising a hydroxyalkyl starch derivative and a cytotoxic agent, the cytotoxic agent comprising at least one secondary hydroxyl group, wherein the hydroxyalkyl starch is linked via said secondary hydroxyl group to the cytotoxic agent. The conjugate according to the present invention has a structure according to the following formula HAS?(-L-M)n wherein M is a residue of the cytotoxic agent, L is a linking moiety, HAS? is the residue of the hydroxyalkyl starch derivative, and n is greater than or equal to 1, and wherein the hydroxyalkyl starch derivative has a mean molecular weight (MW) above the renal threshold.
    Type: Application
    Filed: July 11, 2011
    Publication date: July 18, 2013
    Applicant: Fresenius Kabi Deutschland GmbH
    Inventors: Helmut Knoller, Dominik Heckmann, Frank Hacket, Norbert Zander, Frank Nocken, Saswata Lahiri, Nitin Gupta, Sunil Sanghani, Azim Abul, Hemant Kumar Singh, Sandeep Grewal, Sandeep Kaur
  • Patent number: 8444819
    Abstract: There are disclosed cationic crosslinked waxy starch products having a Brookfield viscosity of about 700 cps to about 2500 cps and a method for preparing the starch products. Also disclosed is the use of the cationic crosslinked waxy starch products having a Brookfield viscosity of about 700 cps to about 2500 cps in the production of paper products.
    Type: Grant
    Filed: June 16, 2004
    Date of Patent: May 21, 2013
    Assignee: Cargill, Incorporated
    Inventors: Kevin R. Anderson, David E. Garlie, James D. Steinke
  • Publication number: 20120231150
    Abstract: The present invention provides for a digestive enzyme inhibitor comprising the hydrolysis products of an ?-amylase hydrolyzed hydroxypropyl substituted starch. The present invention further provides for a food or beverage ingredient composition comprising the hydrolysis products of an ?-amylase hydrolyzed hydroxypropyl substituted starch and a rapidly digestible starch, a food or beverage comprising such ingredient, and methods of use thereof, including a method of controlling postprandial glucose release after ingestion of a rapidly digestible starch.
    Type: Application
    Filed: March 7, 2012
    Publication date: September 13, 2012
    Applicant: TATE & LYLE INGREDIENTS AMERICAS, LLC
    Inventors: Xian-Zhong Han, Rohit A. Medhekar, Andrew J. Hoffman
  • Publication number: 20120172586
    Abstract: The present invention relates to a process for preparing a chemically modified polysaccharide, preferably starch, by using a microdevice. It further relates to the use of a microdevice for the chemical reactions of polysaccharides in heterogeneous mixtures. Examples of chemical modifications are acetylation, oxidation, hydroxypropylation and the like.
    Type: Application
    Filed: August 19, 2010
    Publication date: July 5, 2012
    Applicant: CARGILL INCORPORATED
    Inventors: Marc Charles Florent Berckmans, Rita Maria Delrue, Bruno Frédéric Stengel
  • Patent number: 8168778
    Abstract: An object of the present invention is to provide a novel starchy substance having a retrogradation-resistance, a process for producing the starchy substance efficiently from a material starch by enzymatic reaction, and uses thereof. The present invention attains the above object by providing branched starch having 6-?-maltosyl- and/or 6-?-maltotetraosyl-structure(s) with a marked retrogradation-resistance, a process for producing the branched starch without lowering the molecular weight of material starch, and uses thereof.
    Type: Grant
    Filed: March 14, 2006
    Date of Patent: May 1, 2012
    Assignee: Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo
    Inventors: Tomoyuki Nishimoto, Katsuhiko Hino, Takanori Okura, Hiroto Chaen, Shigeharu Fukuda, Toshio Miyake
  • Patent number: 8133991
    Abstract: An allergen inactivating agent is provided which has no adverse effects on the human body and which does not cause problems such as color development.
    Type: Grant
    Filed: January 31, 2005
    Date of Patent: March 13, 2012
    Assignee: Kao Corporation
    Inventors: Mami Nonomura, Kimihiko Hori, Hiroshi Nojiri, Hiroyuki Yanagida, Fumiko Okuda
  • Patent number: 8119792
    Abstract: The invention relates to novel transglycosylation products and their preparation. The transglycosylation products according to the invention are prepared from starch derivatives, such as esters or ethers of starch. The products are obtained by reacting a starch derivative with an alcohol in the presence of an acid catalyst. The forming product is separated by precipitation or by removing any unreacted alcohol by evaporation. In the products according to the invention the good properties of starch derivatives, such as the excellent water resistance of esters, are combined with the versatility of transglycoside products. The products can be used as adhesives, in which case they are formulated, for example as hot-melt adhesives, and as comonomers, prepolymers or macroinitiators in the preparation of polymers.
    Type: Grant
    Filed: February 17, 2003
    Date of Patent: February 21, 2012
    Assignee: Valtion Teknillinen Tutkimuskeskus
    Inventors: Soili Peltonen, Hannu Mikkonen, Thomas Gädda
  • Patent number: 8076473
    Abstract: A starch thinning and etherification process is provided comprising the steps of (a) mixing a starch substrate with a thinning agent, an alkalizing agent and an etherification agent; (b) drying the mixture of step (a); and (c) allowing the dried mixture to react with the etherification agent, wherein: the thinning agent consists of one or more hypochlorites; step (a) is carried out at an alkaline pH and does not involve any artificial heating; and step (b) is carried out before the mixture of step (a) reaches the starch substrate's gelatinisation temperature.
    Type: Grant
    Filed: December 21, 2006
    Date of Patent: December 13, 2011
    Assignee: Cargill, Incorporated
    Inventors: Marc Charles Florent Berckmans, Dogan Sahin Sivasligil
  • Patent number: 8071572
    Abstract: The present invention relates to a preventive/remedy for obesity, which has a hydroxypropylated starch as its active ingredient. Provided are materials for foods, drugs, etc. which can exhibit an effect of preventing/lessening the onset of various lifestyle related diseases, for example, an effect of preventing/ameliorating obesity, or preventing/ameliorating hyperlipidemia; have a high safety and a wide application range; and rarely damage their texture.
    Type: Grant
    Filed: March 8, 2004
    Date of Patent: December 6, 2011
    Assignee: Kao Corporation
    Inventors: Akira Shimotoyodome, Junko Suzuki, Noriyuki Yajima, Takatoshi Murase, Ichirou Tokimitsu
  • Patent number: 8049003
    Abstract: A particulate SAE-CD composition is provided. The SAE-CD composition has an advantageous combination of physical properties not found in known solid forms of SAE-CD. In particular, the SAE-CD composition possesses an advantageous physicochemical and morphological property profile such that it can be tailored to particular uses. The SAE-CD composition of the invention has improved flow and dissolution performance as compared to known compositions of SAE-CD.
    Type: Grant
    Filed: April 23, 2008
    Date of Patent: November 1, 2011
    Assignee: CyDex Pharmaceuticals, Inc.
    Inventors: Gerold L. Mosher, James D. Pipkin, Douglas B. Hecker
  • Publication number: 20110150777
    Abstract: A medical magnetic resonance tomography apparatus and a contrast agent for magnetic resonance tomography imaging of cavities in a patient are provided. The contrast agent is formed from a highly viscous magnetic resonance contrast agent. The highly viscous magnetic resonance contrast agent includes a substance. A specific magnetic resonance contrast can be generated by the substance.
    Type: Application
    Filed: December 15, 2010
    Publication date: June 23, 2011
    Inventor: Sebastian Schmidt
  • Patent number: 7932377
    Abstract: A molecular complex of a high molecular weight carrier substance and of a medicinal substance. The carrier substance has functional groups whereby the carrier substance and the medicinal substance are bound non-covalently. The medicinal substance is insoluble or slightly soluble in water and the carrier substance is readily soluble in water. The carrier substance can be starch or a starch derivative and can have only one functional group for non-covalent binding of the medicinal substance in each molecule.
    Type: Grant
    Filed: May 28, 2004
    Date of Patent: April 26, 2011
    Assignee: Supramol Parenteral Colloids GmbH
    Inventor: Klaus Sommermeyer
  • Patent number: 7932378
    Abstract: A process for manufacturing transglycosylation products. According to the process, a starch derivative is reacted at acidic conditions with an alkanol containing 1-6 hydroxyl groups and the reaction product is recovered as such or it is subjected to further processing. According to the method, the transglycosylation reaction between the starch derivatives and the alkanol is carried out in a reactive extrusion process, whereby the reaction can essentially be performed in the absence of liquid media at high yield. The invention also relates to new transglycosylation products of starch derivative, containing anions derived from a phosphorus-containing acid, which are chemically bonded to the product.
    Type: Grant
    Filed: October 24, 2003
    Date of Patent: April 26, 2011
    Assignee: Valtion Teknillinen Tutkimuskeskus
    Inventors: Hannu Mikkonen, Kyösti Valta, Eino Sivonen, Soili Peltonen
  • Patent number: 7868166
    Abstract: A process is described for the continuous preparation and/or workup of polysaccharide derivatives by reaction and/or conditioning in a suspension with liquid reaction partners, in which, in accordance with FIG. 1, a) a preferably pumpable suspension stream of solids SE and liquid phase LE, if appropriate preheated to 185° C.
    Type: Grant
    Filed: May 2, 2003
    Date of Patent: January 11, 2011
    Inventors: Volker Eckhardt, Martin Lohrie, Bernd Schriewer, Holger Tanneberger
  • Patent number: 7863260
    Abstract: Described are a hydroxyethylstarch, a process for the preparation thereof, a pharmaceutical formulation containing such a hydroxyethylstarch, and the use of the pharmaceutical formulation for the preparation of a volume replacement, a plasma replacement or a plasma volume expander, as well as the use of the pharmaceutical formulation for maintaining normovolemia and/or for improving the macro- and microcirculation and/or for improving the nutritive oxygen supply and/or for stabilizing hemodynamics and/or for improving the volume efficiency and/or for reducing the plasma viscosity and/or for increasing anemia tolerance and/or for hemodilution, especially for therapeutic hemodilution in disturbed blood supply and arterial, especially peripheral arterial, occlusive diseases.
    Type: Grant
    Filed: March 1, 2005
    Date of Patent: January 4, 2011
    Assignee: B. Braun Melsungen AG
    Inventors: Michael Boll, Andreas Fisch, Donat R. Spahn
  • Publication number: 20100298266
    Abstract: Described are a hydroxyethylstarch, a process for the preparation thereof, a pharmaceutical formulation containing such a hydroxyethylstarch, and the use of the pharmaceutical formulation for the preparation of a volume replacement, a plasma replacement or a plasma volume expander, as well as the use of the pharmaceutical formulation for maintaining normovolemia and/or for improving the macro- and microcirculation and/or for improving the nutritive oxygen supply and/or for stabilizing hemodynamics and/or for improving the volume efficiency and/or for reducing the plasma viscosity and/or for increasing anemia tolerance and/or for hemodilution, especially for therapeutic hemodilution in disturbed blood supply and arterial, especially peripheral arterial, occlusive diseases.
    Type: Application
    Filed: August 4, 2010
    Publication date: November 25, 2010
    Inventors: Michael Boll, Andreas Fisch, Donat R. Spahn
  • Patent number: 7816516
    Abstract: The invention relates to compounds, comprising a conjugate of hydroxyalkyl starch (HAS) and an active agent, whereby the hydroxyalkyl starch is either directly covalently bonded to the active agent, or by means of a linker. The invention further relates to methods for the production of a covalent HAS-active agent conjugate, whereby HAS and an active agent are reacted in a reaction medium, characterised in that the reaction medium is water or a mixture of water and an organic solvent, comprising at least 10 wt. % water.
    Type: Grant
    Filed: March 15, 2002
    Date of Patent: October 19, 2010
    Assignee: Fresenius Kabi Deutschland GmbH
    Inventors: Klaus Sommermeyer, Wolfram Eichner, Sven Frie, Cornelius Jungheinrich, Roland Scharpf, Katharina Lutterbeck, Jurgen Hemberger, Michele Orlando
  • Publication number: 20100158831
    Abstract: The present invention relates to a method for the production of a viscosity regulator by introducing hydrophobic and hydrophilic groups into a starch molecule. The invention also relates to viscosity regulators produced in this manner and the use thereof. The viscosity regulators according to the invention can be used as emulsifiers or as thickening agents of surfactant-containing systems, e.g. in cosmetic or pharmaceutical preparations.
    Type: Application
    Filed: March 28, 2008
    Publication date: June 24, 2010
    Inventors: Bert Volkert, André Lehmann, Heiko Nerenz, Andreas Achrader
  • Publication number: 20100029928
    Abstract: The invention relates to an emulsifier, a method for preparing said emulsifier, and to its use in various applications, primarily food and cosmetic applications. The invention also relates to the use of said emulsifier for the creation of an elastic, gelled foam. An emulsifier according to the invention is based on a starch which is enzymatically converted, using a specific type of enzyme, and modified in a specific esterification reaction.
    Type: Application
    Filed: July 10, 2006
    Publication date: February 4, 2010
    Inventors: Hendrik Jan De Vries, Cindy Semeijn, Pieter Lykle Buwalda
  • Patent number: 7595007
    Abstract: Water-soluble amino acid copolymers, modified polysaccharides, acrylamide polymers, and combinations thereof, are described, for uses including flocculation of solids, particularly flocculation of soil, such as in an agricultural setting. Also described are methods of preparing selected amino acid copolymers and modified polysaccharides.
    Type: Grant
    Filed: June 22, 2006
    Date of Patent: September 29, 2009
    Assignees: Aquero Company, ValuGen LLC
    Inventors: C. Steven Sikes, Mark A. Hochwalt, T. Daniel Sikes
  • Patent number: 7550446
    Abstract: Known hydroxyethylated and -propylated starch types for use as colloid osmotic agent in peritoneal dialysis or as volume replacement composition (plasma expander) have the disadvantage that complete degradation by amylase is not possible owing to the more or less extensive substitution by hydroxyethyl or hydroxypropyl groups. As a consequence thereof, residual fragments remain in the body and are eliminated only very slowly or are stored in various organs/tissues, especially with relatively high and/or long-term dosage. These disadvantageous properties can be very substantially avoided according to the invention with a highly branched, unsubstituted or low-substituted starch product, i.e. with a starch which has a significantly higher degree of branching than amylopectin, and has the degree of ?-I,6 branching of glycogen, or exceeds the latter and—if substituted—has a degree of substitution MS of only up to 0.3.
    Type: Grant
    Filed: July 30, 2003
    Date of Patent: June 23, 2009
    Assignee: Fresenius Kabi Deutschland GmbH
    Inventor: Klaus Henning
  • Patent number: 7365190
    Abstract: New crosslinked polysaccharides useful as absorbents or superabsorbents alone or in a mixture are obtained by reacting polysaccharides (preferably containing carboxylates groups) with at least one crosslinker selected in the group constituted by activated polyethylene glycols such as for example halogenated (Cl, Br, I), mesylated, tosylated, or triflated activated polyethylene glycols.
    Type: Grant
    Filed: November 9, 2001
    Date of Patent: April 29, 2008
    Assignee: Archer-Daniels-Midland Company
    Inventors: Claude Couture, David Bergeron, Frédéric Picard
  • Publication number: 20070221098
    Abstract: The present invention relates to the use of methylated starches in mineral building materials.
    Type: Application
    Filed: March 22, 2007
    Publication date: September 27, 2007
    Applicant: Wolff Cellulosics GmbH & Co. KG
    Inventors: Peter Wolbers, Karsten Bohme, Roland Bayer
  • Patent number: 7244839
    Abstract: The present invention is directed to a starch comprising a novel percentage of actual amylose. A grain comprising the starch is also embodied by the present invention. The present invention is also directed to a plant comprising the novel starch.
    Type: Grant
    Filed: March 26, 2003
    Date of Patent: July 17, 2007
    Assignee: E. I. du Pont de Nemours and Company
    Inventors: Richard W. Pearlstein, Karen E. Broglie, Christopher F. Hines
  • Patent number: 7157573
    Abstract: The invention relates to a process for preparing a hydrophobic starch, comprising etherification, esterification or amidation of a root or tuber starch comprising at least 95 wt. % of amylopectin, based on dry substance of the starch, or a derivative thereof, with a substituent comprising an alkyl chain having from 4–24 carbon atoms. The invention further relates to a hydrophobic starch obtainable by said process.
    Type: Grant
    Filed: August 17, 2005
    Date of Patent: January 2, 2007
    Assignee: Cooperatie Avebe U.A.
    Inventors: Pieter Lykle Buwalda, Ronald Peter W. Kesselmans, Augustinus Arnoldus M. Maas, Hylke Hotze Simonides
  • Patent number: 6846497
    Abstract: This invention relates to a starch based tablet disintegrant useful at low addition levels and providing equally effective properties in water and physiological fluids. The starches are characterized by their low solubility in cold water, high swelling power and labile birefringence in the dry state, which rapidly disappears upon addition of water. The preferred starches are inhibited then processed to remove a portion of the granular structure.
    Type: Grant
    Filed: January 30, 2003
    Date of Patent: January 25, 2005
    Assignee: National Starch and Chemical Investment Holding Corporation
    Inventors: Monika K. Okoniewska, James J. Kasica, Eric M. Weisser
  • Publication number: 20040242861
    Abstract: Disclosed is a method for preparing a hydroxyalkyl starch. In accordance with the disclosed invention, the method comprises reacting the starch with a starch hydroxylating agent in the presence of an alcohol and an alcohol-soluble alkali metal, at a temperature effective to provide a cold water soluble starch, preferably at a temperature of between about 90° and about 110° C. The starch thus produced will be granular and cold water soluble.
    Type: Application
    Filed: March 22, 2004
    Publication date: December 2, 2004
    Applicant: Grain Processing Corporation
    Inventors: Adrian P. Kightlinger, Richard L. Antrim
  • Publication number: 20040171580
    Abstract: The present invention describes a class of new regioselectively reticulated polysaccharides. A process to obtain these polysaccharides, starting from naturally occurring, possibly substituted polysaccharides, is also described. The products can be used in the medical filed and in other industrial sectors.
    Type: Application
    Filed: December 10, 2003
    Publication date: September 2, 2004
    Inventors: Luca Stucchi, Alessandro Rastrelli
  • Publication number: 20040151767
    Abstract: This invention relates to a starch based tablet disintegrant useful at low addition levels and providing equally effective properties in water and physiological fluids. The starches are characterized by their low solubility in cold water, high swelling power and labile birefringence in the dry state, which rapidly disappears upon addition of water. The preferred starches are inhibited then processed to remove a portion of the granular structure.
    Type: Application
    Filed: January 30, 2003
    Publication date: August 5, 2004
    Inventors: Monika K. Okoniewska, James J. Kasica, Eric M. Weisser
  • Publication number: 20040039191
    Abstract: The invention relates to a highly substituted carboxyalkyl starch which is obtained by a special slurry method. A conversion of starch with halogenated acids is thereby effected in an organic-aqueous reaction medium in the presence of alkali hydroxide. This starch is used in the chemical industry field.
    Type: Application
    Filed: April 4, 2003
    Publication date: February 26, 2004
    Inventors: Bert Volkert, Fritz Loth, Waldemar Lazik, Wolfgang Koch, Alexandra Hild
  • Publication number: 20030220492
    Abstract: A process is described for the continuous preparation and/or workup of polysaccharide derivatives by reaction and/or conditioning in a suspension with liquid reaction partners, in which, in accordance with FIG.
    Type: Application
    Filed: May 2, 2003
    Publication date: November 27, 2003
    Inventors: Volker Eckhardt, Martin Lohrie, Bernd Schriewer, Holger Tanneberger
  • Patent number: 6600033
    Abstract: The invention relates to a cellulose ether that is hydrophobically modified with an alkyl or alkenylketene dimer of general formula (I), in which R1 and R2 are alkyl or alkenyl chain, such as one having 5 to 22, preferably 13 to 20, most preferably 14 to 18 carbons. The product can be used in water-based products to control the rheological properties, for example. Objects of use include, for example, detergents, paper coating mixtures, paints, dispersing agents, and oil drilling muds.
    Type: Grant
    Filed: June 19, 2000
    Date of Patent: July 29, 2003
    Assignee: Metsa Specialty Chemicals Oy
    Inventors: Mikko Lähteenmäki, Heidi Känköhen, Göran Kloow, Oliver Ruppert, Jennifer Ann Leupin, Eugene Paul Gosselink
  • Publication number: 20030073798
    Abstract: Disclosed is a method for preparing a hydroxyalkyl starch. In accordance with the disclosed invention, the method comprises reacting the starch with a starch hydroxylating agent in the presence of an alcohol and an alcohol-soluble alkali metal, at a temperature effective to provide a cold water soluble starch, preferably at a temperature of between about 90° and about 110° C. The starch thus produced will be granular and cold water soluble.
    Type: Application
    Filed: June 12, 2002
    Publication date: April 17, 2003
    Applicant: Grain Processing Corporation
    Inventors: Adrian P. Kightlinger, Richard L. Antrim
  • Patent number: 6512108
    Abstract: A substantially fat impervious coating (KIT number from about 6 and about 16) coating made from an aqueous solution of a hydroxypropyl high amylose pea starch.
    Type: Grant
    Filed: February 27, 2001
    Date of Patent: January 28, 2003
    Assignee: Gesellschaft fuer Spezialfolien-Entwicklung m.b.H.
    Inventors: Rotraut Albrecht, Silvio Boettcher, Gernod Haerter, Peter Pawlak, Erich Heinrich Schwartze, Heike Zuleg
  • Patent number: 6469120
    Abstract: The composition formed by mixing an organosilane, optionally having a nonhydrolizable organic group, but having one or more hydrolyzable groups, with a polyol containing at least two hydroxy groups, wherein at least any two of the hydroxy groups are separated by no more than two intervening atoms. Water-stabilized organosilane compounds. A water stable composition made from the polyol and organosilane or compound and water. A method of treating a substrate by mixing or contacting the substrate with the product, compound, or composition of this invention for a period of time sufficient for treatment of the substrate. A treated substrate having adhered thereto the product, compound, or composition of this invention. A method of dyeing and treating a substrate. A method of antimicrobially treating a food article. A method of antimicrobially coating a fluid container. A method of antimicrobially coating a latex medical article. A method of making a siloxane in the presence of a stabilizer.
    Type: Grant
    Filed: June 9, 2000
    Date of Patent: October 22, 2002
    Assignee: BioShield Technologies, Inc.
    Inventors: Jacques E. Elfersy, Joachim Berkner, Timothy C. Moses
  • Patent number: 6368456
    Abstract: This invention relates to paper comprising aldehyde modified cellulose pulp prepared using nitroxyl radical mediated oxidation and further containing selected additives comprising aldehyde functional polymers or polymers containing functionality capable of reacting with aldehyde groups and having improved strength properties. This invention further relates to paper made from aldehyde modified cellulose pulp where an hydroxyl group containing polymer is added to the paper to provide wet strength properties.
    Type: Grant
    Filed: December 3, 1999
    Date of Patent: April 9, 2002
    Assignee: National Starch and Chemical Investment Holding Corporation
    Inventors: A. Levent Cimecioglu, John S. Thomaides, Kraig A. Luczak, Robert D. Rossi