Esters Patents (Class 536/115)
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Patent number: 10071371Abstract: Provided are ozone decomposing compositions comprising a solvent and a polymer. The polymer comprises a structural repeat unit comprising an unsubstituted or substituted carbohydrate moiety. Also provided are methods of decomposing ozone using the compositions, and spray coatings, items of clothing, fabrics, carpets, paints, sealants, finishes, air-filters, face-masks, cosmetics, creams, lotions and coatings incorporating the polymer.Type: GrantFiled: June 5, 2017Date of Patent: September 11, 2018Inventor: Christopher Duke
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Patent number: 9717658Abstract: The invention relates especially to a composition in the form of an oil-in-water emulsion comprising an inner fatty phase and an outer aqueous phase and containing: a) at least 0.01% by weight and preferably at least 0.05% by weight, relative to the total weight of the composition, of at least one inulin modified with hydrophobic chains, and b) at least 0.05% by weight and preferably at least 0.1% by weight, relative to the total weight of the composition, of at least one thickening polysaccharide of plant origin, the said composition being free of silicones. The invention also relates to a cosmetic process using the said composition.Type: GrantFiled: December 17, 2008Date of Patent: August 1, 2017Assignee: L'OREALInventor: Raluca Lorant
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Patent number: 9669401Abstract: Disclosed herein are ozone reactive polymers comprising a structural repeat unit represented by the following formula XLI: wherein A is absent or a linking group selected from the group consisting of substituted or unsubstituted alkylene, substituted or unsubstituted heteroalkylene, substituted or unsubstituted cycloalkylene, substituted or unsubstituted heterocycloalkylene, substituted or unsubstituted arylene, substituted or unsubstituted heteroarylene, substituted or unsubstituted arylalkylene, and substituted or unsubstituted heteroarylalkylene; each of R1 and R2 is, independently, selected from the group consisting of hydrogen, substituted or unsubstituted alkyl, substituted or unsubstituted heteroalkyl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted heterocycloalkyl, substituted or unsubstituted aryl, substituted or unsubstituted heteroaryl, substituted or unsubstituted arylalkyl, and substituted or unsubstituted heteroarylalkyl; and wherein the structural repeat unit compriseType: GrantFiled: August 8, 2015Date of Patent: June 6, 2017Inventor: Christopher Duke
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Patent number: 9011961Abstract: Disclosed are methods for producing esterified propoxylated glycerols and eutectic mixtures containing one or more esterified propoxylated glycerols and one or more digestible fats. Food products containing the eutectic mixtures are also disclosed.Type: GrantFiled: October 28, 2013Date of Patent: April 21, 2015Assignees: Choco Finesse LLC, Kansas State University Institute for CommercializationInventors: Leopold Strecker, David Rowe, James Louis Flowers, Dana Overman
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Patent number: 8912168Abstract: A modified starch material for biocompatible hemostasis, biocompatible adhesion prevention, tissue healing promotion, absorbable surgical wound sealing and tissue bonding, when applied as a biocompatible modified starch to the tissue of animals. The modified starch material produces hemostasis, reduces bleeding of the wound, extravasation of blood and tissue exudation, preserves the wound surface or the wound in relative wetness or dryness, inhibits the growth of bacteria and inflammatory response, minimizes tissue inflammation, and relieves patient pain. Any excess modified starch not involved in hemostatic activity is readily dissolved and rinsed away through saline irrigation during operation. After treatment of surgical wounds, combat wounds, trauma and emergency wounds, the modified starch hemostatic material is rapidly absorbed by the body without the complications associated with gauze and bandage removal.Type: GrantFiled: September 5, 2013Date of Patent: December 16, 2014Inventor: Xin Ji
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Patent number: 8865241Abstract: The invention relates to mutant strains of the genus Sphingomonas which have a mutation in at least one gene encoding a protein involved in polyhydroxybutyrate (“PHB”) synthesis that allows the mutant strains to produce PHB-deficient Sphingans. The invention is also directed to a process for preparing a clarified Sphingan solution comprising heating aqueous Sphingan solution, in particular PHB-deficient Sphingan solution, to a clarification temperature of about 30° C. to about 70° C., and treating the solution with a clarification agent and enzymes. In addition, the invention is directed to a food or industrial product comprising a PHB-deficient and/or clarified Sphingan. One particular embodiment of the invention is directed to a clarified, PHB-deficient high-acyl gellan and the processes of making thereof.Type: GrantFiled: September 29, 2010Date of Patent: October 21, 2014Assignee: CP Kelco U.S., Inc.Inventors: Stan Bower, Ellen Burke, Nancy E. Harding, Yamini N. Patel, J. Carrie Schneider, Dagmar Meissner, Neil A. Morrison, Ralph Bezanson
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Publication number: 20140235848Abstract: A method that can be used to make a precursor of L-fucose from D-glucose that includes the steps of a) making a compound of formula (1) from D-glucose, formula (1) wherein R1 is acyloxy, and Q is a group (a), (b), (c) or (d), formula (a), (b), (c) or (d) or wherein R1 is OH, and Q is a group (e), (f) or (g); formula (e), (f) or (g) wherein R2 is acyloxy and R3 is a sulphonyl leaving group; and b) producing 6-deoxy-L-talose from the compound of formula (1) formed in step a), wherein the moiety is a highly lipophilic protecting group; compounds according to formula (1), and use of a compound according to formula (1) are provided.Type: ApplicationFiled: September 28, 2012Publication date: August 21, 2014Applicant: Glycom A/SInventors: Julien BOUTET, Nikolay KHANZHIN, Filippo BONACCORSI, Gyula DEKANY
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Patent number: 8715764Abstract: Disclosed are methods for producing esterified propoxylated glycerols and eutectic mixtures containing one or more esterified propoxylated glycerols and one or more digestible fats. Food products containing the eutectic mixtures are also disclosed.Type: GrantFiled: June 21, 2012Date of Patent: May 6, 2014Assignees: Choco Finesse LLC, Kansas State University Institute for CommercializationInventors: Leopold Strecker, David Stewart Rowe, James Louis Flowers, Dana Overman
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Patent number: 8679569Abstract: Disclosed herein are compositions that include a blend of sucrose polyesters, wherein each sucrose polyester includes a sucrose moiety and a plurality of fatty acid ester moieties, wherein a percentage range of the combined fatty acid ester moieties of the sucrose polyesters in the blend have a carbon chain that has trans content.Type: GrantFiled: December 1, 2010Date of Patent: March 25, 2014Assignee: The Procter & Gamble CompanyInventors: Donald Benjamin Appleby, Deborah Jean Back
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Publication number: 20140045218Abstract: A surfactant produced by reacting naturally occurring polysaccharides that are not water soluble with a hydrophilic substituent on a carboxylic portion of the polysaccharide. In a second reaction, the surfactant is further substituted on a hydroxylic portion with a hydrophobic or lipophilic substituent, so as to make the reaction product both water soluble and capable of attracting oily material that is hydrophobic to be removed from a substrate by cleaning in water. Methods of making the surfactant and the follow-on reaction product are described.Type: ApplicationFiled: March 15, 2013Publication date: February 13, 2014Applicant: University of MassachusettsInventors: Zarif Farhana Mohd Aris, Ryan M. Bouldin, Ramaswamy Nagarajan, Bridgette Budhlall, Vishal Bavishi
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Patent number: 8609834Abstract: The present invention discloses a method of synthesizing sucrose-6-acetic ester, comprising the following steps: adding sucrose into a polar aprotic solvent, and stirring the solvent to dissolve it, then generate a suspension solution of sucrose; adding a acetylation agent acetylnitrile into said suspension solution and stirring the solution; adding water into the aforesaid reaction solution, and then concentrating it to generate a concentrated product; adding a crystalline solvent into the concentrated product, stirring to dissolve it, and depositing for crystallization, then filtering and drying it to get a product of sucrose-6-acetic ester. The benefit of the present invention is that the method of synthesizing sucrose-6-acetic ester has simple operation, mild reaction condition, high selectivity, high yield, and is suitable for industrial production.Type: GrantFiled: November 8, 2007Date of Patent: December 17, 2013Assignee: Shenzhen New Trend Industrial Development Co. Ltd.Inventor: Xiaoqiang Wang
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Patent number: 8569247Abstract: The present invention relates to a composition derived from the hydrolysate of plant containing crocin or the derivatives thereof. The composition includes a significant amount of crocetin monoester. The present invention also provides a method to hydrolyze crocin existing in a plant extract, and further relates to the use.Type: GrantFiled: February 17, 2010Date of Patent: October 29, 2013Assignee: Omnica GmbHInventor: Thomas Eidenberger
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Publication number: 20130102773Abstract: A method of preparing sucralose-6-ester by catalysis and chlorination of phase transfer catalyst comprises the following steps: add phase transfer catalyst into a prepared Vilsmeier reagent and then drip in DMF solution of sucrose-6-ester at 5-10° C. to obtain a feed solution and after that maintain its temperature of the feed solution for 1-1.5 hours; next, increase temperature of the feed solution to 45-55° C. and maintain the temperature for 1-1.5 hours; next, increase the temperature to 75-85° C. and maintain the temperature for 1-1.5 hours; next, increase the temperature to 108-109° C., maintain the temperature for 2.5-3 hours and then remove a chlorine-containing solvent from the feed solution by concentration in reduced pressure for evaporation. After that, cool down the feed solution to room temperature and then pump in ammonia into the feed solution for neutralization.Type: ApplicationFiled: July 26, 2012Publication date: April 25, 2013Applicant: HUBEI YITAI PHARMACEUTICAL CO.,LTD.Inventor: Zhengyou WANG
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Publication number: 20130018005Abstract: The present invention provides a compound of formula I; a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.Type: ApplicationFiled: September 13, 2012Publication date: January 17, 2013Applicant: NOVARTIS AGInventor: Gregory Raymond BEBERNITZ
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Publication number: 20120172586Abstract: The present invention relates to a process for preparing a chemically modified polysaccharide, preferably starch, by using a microdevice. It further relates to the use of a microdevice for the chemical reactions of polysaccharides in heterogeneous mixtures. Examples of chemical modifications are acetylation, oxidation, hydroxypropylation and the like.Type: ApplicationFiled: August 19, 2010Publication date: July 5, 2012Applicant: CARGILL INCORPORATEDInventors: Marc Charles Florent Berckmans, Rita Maria Delrue, Bruno Frédéric Stengel
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Patent number: 8188267Abstract: Ionic liquids and cellulose ester compositions and processes for producing ionic liquids and cellulose esters. Cellulose esters can be produced by esterifying cellulose in a reaction medium comprising one or more ionic liquids. Cellulose esters prepared via the methods of the present invention can be contacted with at least one bleaching agent to produce bleached cellulose esters having a ?E value of less than 30.Type: GrantFiled: August 11, 2008Date of Patent: May 29, 2012Assignee: Eastman Chemical CompanyInventors: Charles Michael Buchanan, Norma Lindsey Buchanan
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Publication number: 20120088909Abstract: Process for esterifying, etherifying or silylating polysaccharide or derivatives thereof by means of an esterifying reagent, etherifying reagent or silylating reagent in the presence of an ionic liquid, in which (a) the process is carried out under heterogeneous reaction conditions, and (b) the amount of ionic liquid is 2% to 25% by weight, based on the polysaccharide or derivatives thereof.Type: ApplicationFiled: March 2, 2010Publication date: April 12, 2012Applicant: Fraunhofer-Gesellschaft zur Forderung der angewandten Forschung E.V.Inventors: André Lehmann, Bert Volkert
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Patent number: 8153849Abstract: Methods of recovering a triarylmethyl halide from a sucrose derivatization process include the steps of (a) forming a mixture including 1) a triarylmethylated sucrose derivative including at least one triarylmethyl substituent and at least one acyl substituent on the sucrose, 2) triarylmethylated sucrose ester byproducts, and 3) an amine; (b) separating from the output of step (a) i) the triarylmethylated sucrose derivative, and ii) a mixture including the triarylmethylated sucrose ester byproducts and the amine; (c) removing the amine from the mixture of step (b) ii); (d) contacting the product of step (c) with hydrogen halide to cleave triarylmethyl groups and thereby form a crude triarylmethyl halide component; (e) contacting the crude triarylmethyl halide component with hydrogen halide to form a purified triarylmethyl halide component; and (f) recovering the triarylmethyl halide from the output of step (e).Type: GrantFiled: December 4, 2007Date of Patent: April 10, 2012Assignee: Tate & Lyle Technology Ltd.Inventors: Stephen C. Scherrer, Anne P. Noonan, Thomas K. Hutton
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Publication number: 20110232159Abstract: The invention provides an additive for lowering the minimum usable temperature of a biodiesel fuel or a diesel/biodiesel blend. The additive comprises at least one saccharide ester and a polymer having a comb structure. In some instances there is only one saccharide ester present. In this case the saccharide ester comprises at least one saturated ester group and at least one unsaturated ester group. In other instances, there is more than one saccharide ester is present. In these cases the additive comprises a first saccharide ester comprising at least one saturated ester group and a second saccharide ester comprising at least one unsaturated ester group.Type: ApplicationFiled: May 26, 2009Publication date: September 29, 2011Applicant: Meat & Livestock Australia LimitedInventors: Andrew Westlake, Stewart McGlashan, Stephen Clarke, Mark Fisher, Rachel Pillar, Kristina Constantopoulos, Simon Mathew, Elda Markovic, Eleni Papadopoulos, David John Clarke, Kim Anh-Thi Nguyen
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Patent number: 7989599Abstract: The present invention includes as an active ingredient at least one biosurfactant, in particular mannosyl alditol lipid (such as MEL and MML) or triacylated mannosyl alditol lipid. This allows providing an activator and anti-aging agent that is excellent in activating and anti-aging effects on cells and that is safe enough to be used for a long time, and also providing cosmetics, quasi-drugs, drugs, and drinks and foods including the activator and the anti-aging agent as active ingredients. Further, the present invention provides MEL whose mannosyl erythritol skeleton in a molecular structure is 1-O-?-D-mannopyranosyl-meso-erythritol and a method for producing the MEL with use of a microorganism.Type: GrantFiled: February 9, 2009Date of Patent: August 2, 2011Assignees: Toyo Boseki Kabushiki Kaisha, National Institute of Advanced Industrial Science and TechnologyInventors: Michiko Suzuki, Masaru Kitagawa, Shuhei Yamamoto, Atsushi Sogabe, Dai Kitamoto, Tomotake Morita, Tokuma Fukuoka, Tomohiro Imura
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Publication number: 20110180760Abstract: The invention relates to a hot melt adhesive, comprising at least one polysaccharide ester gained by a reaction of a polysaccharide with an imidazolide in melted imidazole. The invention relates, further, to a process for producing the hot melt adhesive, in which imidazole is melted, and an acid chloride and/or an acid anhydride and/or a lactone is reacted in and with the melted imidazole to form an imidazolide, whereby at least one polysaccharide is added to the melted imidazole, whereby the polysaccharide is reacted with the imidazolide to form a polysaccharide ester.Type: ApplicationFiled: November 16, 2010Publication date: July 28, 2011Inventors: Bernd Grünler, Andreas Heft, Marion Homuth, Thomas Heinze, Tim Liebert
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Publication number: 20110059910Abstract: The invention relates to substituted aromatic fluoroglycoside derivatives, and to the physiologically compatible salts and physiologically functional derivatives thereof. The invention also relates to methods of lowering blood sugar and the treatment of type I and type II diabetes.Type: ApplicationFiled: August 6, 2010Publication date: March 10, 2011Applicant: SANOFI-AVENTISInventors: Wendelin FRICK, Heiner GLOMBIK, Stefan THEIS, Ralf ELVERT
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Patent number: 7829697Abstract: The invention relates to mutant strains of the genus Sphingomonas which have a mutation in at least one gene encoding a protein involved in polyhydroxybutyrate (“PHB”) synthesis that allows the mutant strains to produce PHB-deficient sphingans. The invention is also directed to a process for preparing a clarified sphingan solution comprising heating aqueous sphingan solution, in particular PHB-deficient sphingan solution, to a clarification temperature of about 30° C. to about 70° C., and treating the solution with a clarification agent and enzymes. In addition, the invention is directed to a food or industrial product comprising a PHB-deficient and/or clarified sphingan. One particular embodiment of the invention is directed to a clarified, PHB-deficient high-acyl gellan and the processes of making thereof.Type: GrantFiled: December 2, 2005Date of Patent: November 9, 2010Assignee: CP Kelco US, Inc.Inventors: Stan Bower, Ellen Burke, Nancy E. Harding, Yamini N. Patel, J. Carrie Schneider, Dagmar Meissner, Neil A. Morrison, Ralph Bezanson
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Publication number: 20100222568Abstract: A process of removal of pyridine or a pyridine analogue from a composition or a Process Stream in a process of production of 4,1?, 6? trichlorogalactosucrose is described comprising reacting pyridine with an acid, the said acid being used preferably in gaseous form, achieving complete precipitation of the salt of pyridine in higher alcoholic solvents and non-polar solvents, filtering off the precipitate of the said salt of pyridine to achieve removal of pyridine from the reaction system and optionally regenerating and recovering pyridine by reacting the said salt with alkali.Type: ApplicationFiled: August 29, 2006Publication date: September 2, 2010Inventors: Rakesh Ratnam, Sundeep Aurora
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Patent number: 7744853Abstract: Radiolabeled annexin and modified annexin conjugates useful for imaging vascular thrombi are described. Methods for making and using such radiolabeled annexin conjugates are also provided.Type: GrantFiled: September 27, 2005Date of Patent: June 29, 2010Assignee: Poniard Pharmaceuticals, Inc.Inventors: Sudhakar Kasina, John M. Reno, Alan R. Fritzberg, Jonathan Tait
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Publication number: 20100160621Abstract: A process for the preparation of an alkoxylated sucrose ester including the steps of: forming an initial reaction mixture of a sucrose ester and from about 0.01% to about 5% of a catalyst; and forming an initial reaction product by reacting the initial reaction mixture with an epoxide for a period of time in the range of from about 30 minutes to about 6 hours and at a temperature in the range of from about 80° C. to about 120° C.; wherein the epoxide and the sucrose ester are selected such that a mole ratio of epoxide groups to sucrose hydroxyls is from about 1 to about 100.Type: ApplicationFiled: December 14, 2009Publication date: June 24, 2010Inventor: Jared John Schaefer
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Patent number: 7683167Abstract: The present invention provides a separating agent for enantiomeric isomers exhibiting high separation power. That is, the present invention provides a separating agent for enantiomeric isomers including, as an active ingredient, a polysaccharide derivative having at least part of hydrogen atoms of hydroxyl groups of a polysaccharide such as cellulose or amylose substituted by at least one of atomic groups represented by the following general formulae (I) and (II): (in the formulae, R represents a substituted or unsubstituted aromatic group, or a linear, branched, or cyclic aliphatic group).Type: GrantFiled: April 22, 2004Date of Patent: March 23, 2010Assignee: Daicel Chemical Industries, Ltd.Inventors: Yoshio Okamoto, Chiyo Yamamoto
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Publication number: 20090318678Abstract: The invention concerns a C-glycoside compound of formula (I); wherein: n is equal to 1 or 2; Y represents H or halogen; X is an alkyl chain bearing at least one amino, amide, acid, ester, carbonyl, alcohol, aryl function or a carbonyl, ester amide, amino, alcohol group; the R's, identical or different, represent a OH or OR? group where R? is an alkyl, benzyl, benzoyl, acetyl, pivaloyl, trialkylsilyl, tertiobutyldiphenylsilyl group or one or more sugars; R1 represents OR?, NR?R??, N3, or a phthalamide with R? and R??, identical or different, represent H or an alkyl, aryl, benzyl, benzoyl, acetyl, alkoxycarbonyl, allyloxycarbonyl, benzyloxycarbonyl group; R2 represents H or halogen or a OH, OR, NR?R?? or N3 group, as well as derivatives thereof in physiologically or pharmaceutically acceptable base, mineral or organic acid-addition salt, hydrate or solvate form.Type: ApplicationFiled: April 23, 2007Publication date: December 24, 2009Applicant: TFCHEMInventors: Géraldine Castelot-Deliencourt-Godefroy, Jean-Charles Quirion, Philippe Jubault, Ludivine Zoute
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Publication number: 20090305997Abstract: The present invention relates to a novel galactose derivatives of general formula (I) and to their use as agents for stimulating the immune system of the skin and/or as immunoregulators, and for preparing a composition containing a cosmetically or pharmaceutically acceptable medium, intended in particular to prevent and/or limit the appearance of cutaneous immune imbalances, in particular related to environmental stresses.Type: ApplicationFiled: April 5, 2007Publication date: December 10, 2009Applicant: L'OREALInventors: Nathalie Pineau, Maria Dalko
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Patent number: 7626016Abstract: This invention relates to a method for preparing a sucrose-6-ester.Type: GrantFiled: August 20, 2007Date of Patent: December 1, 2009Assignee: Hebei Sukerui Science and Technology Co., Ltd.Inventors: Jun Jing Wu, Guang Li Wu, Qing Hai Cai, Shou Xinyu, Zi Wen Li, Shang Liu, Man Tang Wang
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Publication number: 20080269478Abstract: The present invention discloses a method of synthesizing sucrose-6-acetic ester, comprising the following steps: adding sucrose into a polar aprotic solvent, and stirring the solvent to dissolve it, then generate a suspension solution of sucrose; adding a acetylation agent acetylnitrile into said suspension solution and stirring the solution; adding water into the aforesaid reaction solution, and then concentrating it to generate a concentrated product; adding a crystalline solvent into the concentrated product, stirring to dissolve it, and depositing for crystallization, then filtering and drying it to get a product of sucrose-6-acetic ester. The benefit of the present invention is that the method of synthesizing sucrose-6-acetic ester has simple operation, mild reaction condition, high selectivity, high yield, and is suitable for industrial production.Type: ApplicationFiled: November 8, 2007Publication date: October 30, 2008Inventor: Xiaoqiang Wang
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Publication number: 20080139802Abstract: The present process provides an improved method for converting 2?-deoxy-2?-fluoro-2?-methyl-D-ribonolactones derivatives to 3-fluoro-3-methyl-2-chlorofuran compounds which are useful for the synthesis of nucleosides and improved processes for the synthesis of the D-ribonolactone compounds.Type: ApplicationFiled: October 10, 2007Publication date: June 12, 2008Inventors: Steven D. Axt, Byoung-Kwon Chun, Qingwu Jin, Suguna Rachakonda, Bruce Ross, Keshab Sarma, Justin Vitale, Jiang Zhu
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Patent number: 7326542Abstract: The production of a purified extracellular bacterial signal called autoinducer-2 is regulated by changes in environmental conditions associated with a shift from a free-living existence to a colonizing or pathogenic existence in a host organism. Autoinducer-2 stimulates LuxQ luminescence genes, and is believed also to stimulate a variety of pathogenesis related genes in the bacterial species that produce it. A new class of bacterial genes is involved in the biosynthesis of autoinducer-2.Type: GrantFiled: March 10, 2003Date of Patent: February 5, 2008Assignees: Princeton University, University Technologies International, Inc.Inventors: Bonnie L. Bassler, Michael G. Surette
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Patent number: 7304153Abstract: Polyol polyesters useful as nondigestible fat substitutes are prepared by improved heterogeneous interesterification processes between fatty acid esters of easily removable alcohol and polyol characterized by having one or more improvements such as using low levels of soap emulsifying agent, catalyst, and/or excess fatty acid ester; reducing the size of the polyol by mechanical means; removing extraneous particulate material during the reaction; using low temperature and/or high pressure and compensating by increasing the mass transfer area; and/or using backmixing in the initial stage(s) and plug-flow conditions in the final stage(s).Type: GrantFiled: December 20, 1994Date of Patent: December 4, 2007Assignee: The Procter and Gamble Co.Inventors: Donald Benjamin Appleby, David Joseph Bruno, Jr., Patrick Joseph Corrigan, John Keeney Howie, Ju-Nan Kao, Scott David Pearson, Richard Gerard Schafermeyer, Glen Reid Wyness
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Patent number: 7297324Abstract: Microchannel devices and method of use are disclosed wherein a reaction microchamber 52 is in thermal contact with a heat exchange channel 61. An equilibrium limited exothermic chemical process occurs in the reaction microchamber 52. Sufficient heat is transferred to the heat exchange channels to substantially lower the temperature in the reaction microchamber 52 down its length to substantially increase at least one performance parameter of the exothermic chemical process relative to isothermal operation. Optionally, an endothermic reaction occurs in the heat exchange channel 61 which is sustained by the exothermic chemical process occurring the exothermic reaction chamber. Both the reaction chamber 52 and the heat exchange channel 61 can be of micro dimension. Catalyst 75 can be provided in the microchamber 52 in sheet form such that reactants flow by the catalyst sheet.Type: GrantFiled: March 11, 2003Date of Patent: November 20, 2007Assignee: Battelle Memorial InstituteInventors: Ward E. TeGrotenhuis, David L. King, Greg A. Whyatt, Christopher M. Fischer, Robert S. Wegeng, Kriston P. Brooks
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Patent number: 7276485Abstract: A flowable nondigestible oil composition having a Consistency in a temperature range of 20° C. to 40° C. of less than about 600 P.sec(n-1). The flowable nondigestible oil contains a liquid polyol polyester having a complete melt point less than 37° C., and a solid polyol polyester having a complete melt point of at least about 37° C., wherein the solid polyol polyester contains a solid saturated polyol polyester capable of forming crystallized spherulites.Type: GrantFiled: August 19, 1997Date of Patent: October 2, 2007Assignee: The Procter + Gamble Co.Inventors: Michael Kenneth Cerreta, Peter Yau-Tak Lin, Penelope Marie Edwards, Mark Lewis Agerton
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Patent number: 7244839Abstract: The present invention is directed to a starch comprising a novel percentage of actual amylose. A grain comprising the starch is also embodied by the present invention. The present invention is also directed to a plant comprising the novel starch.Type: GrantFiled: March 26, 2003Date of Patent: July 17, 2007Assignee: E. I. du Pont de Nemours and CompanyInventors: Richard W. Pearlstein, Karen E. Broglie, Christopher F. Hines
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Patent number: 7217696Abstract: Disclosed are glycosides, orthoester glycosides and glycuronamides of fluoxetine and analogs thereof to treat conditions and diseases such as depression.Type: GrantFiled: February 27, 2003Date of Patent: May 15, 2007Assignee: A & D Bioscience, Inc.Inventors: Michael F Holick, Halasya Ramanathan
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Patent number: 7157573Abstract: The invention relates to a process for preparing a hydrophobic starch, comprising etherification, esterification or amidation of a root or tuber starch comprising at least 95 wt. % of amylopectin, based on dry substance of the starch, or a derivative thereof, with a substituent comprising an alkyl chain having from 4–24 carbon atoms. The invention further relates to a hydrophobic starch obtainable by said process.Type: GrantFiled: August 17, 2005Date of Patent: January 2, 2007Assignee: Cooperatie Avebe U.A.Inventors: Pieter Lykle Buwalda, Ronald Peter W. Kesselmans, Augustinus Arnoldus M. Maas, Hylke Hotze Simonides
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Patent number: 7112555Abstract: This invention concerns the use of compounds selected among 1,4?-D-glucuronans, and/or glycuronic polysaccharides derived from polymers of formula (I), and whereof the number of saccharide units is less than about 30, and/or esters and/or ethers corresponding to polymers of formula (I) or said oligosccahride derivatives, as phytosanitary products in applications related to their activity for amplifying the 1,3?-D-glucanase enzyme, and/or the 1,4?-D-glucanase, and/or the xyloglucan endotransglycolase.Type: GrantFiled: June 23, 2000Date of Patent: September 26, 2006Assignee: Centre National de la Recherche ScientifiqueInventors: Yvette Lienart, Alain Heyraud, Olivier Sevenou
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Patent number: 7078519Abstract: Methods for forming structurally defined organosilicon carbohydrates are provided. Additionally, structurally defined organosilicon carbohydrates are provided. The structurally defined organosilicon carbohydrates may be formed by contacting a hydrolase enzyme with an organosilicon reactant and a carbohydrate reactant. The enzyme may catalyze the formation of an ester bond between carboxylic acid, ester, or amide functional groups of the organosilicon or carbohydrate reactant and alcohol functional groups of the carbohydrate or organosilicon reactant. The enzyme may catalyze the formation of an amide bond between carboxylic acid, ester, or amide functional groups of the organosilicon or carbohydrate reactant and amine functional groups of the carbohydrate or organosilicon reactant.Type: GrantFiled: August 15, 2003Date of Patent: July 18, 2006Assignees: Dow Corning Corporation, Polytechnic UniversityInventors: Kurt Friedrich Brandstadt, Thomas Howard Lane, Richard A. Gross
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Patent number: 7074919Abstract: The invention concerns the use, in a composition for treating textile fiber articles in aqueous or moist medium, of an amphoteric polysaccharide, whereof the native skeleton is a polysaccharide consisting of a main chain comprising anhydrohexose units and branches comprising at least a neutral or anionic anhydropentose and/or anhydrohexose unit, the anhydrohexose and/or anhydropentose units being substituted of modified by groups bearing at least a (potentially) anionic load and/or at least a (potentially) cationic load, the degree of substitution or modification by the set of said groups bearing (potentially) anionic loads ranging between 0.01 and less than 3, with a ratio of the number of (potentially) anionic charges over the number of (potentially) cationic loads ranging between 99.5/0.Type: GrantFiled: December 20, 2001Date of Patent: July 11, 2006Inventors: Eric Aubay, Etienne Fleury, Ian Harrison
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Patent number: 7033765Abstract: Compounds and methods which are useful for the site-specific delivery and localization of drugs are provided. The compounds can be represented by the formula: A-L-D wherein A is an anchoring moiety; L is a linking group; and D is a drug.Type: GrantFiled: February 19, 1998Date of Patent: April 25, 2006Assignee: Toronto Research Chemicals, Inc.Inventors: David S. Dime, Peter Backx, Klaus Kimmeldirk
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Patent number: 7015200Abstract: The present invention provides compositions comprising at least one GHB moiety bonded to at least one physiologically compatible carrier molecule. The compositions can enhance the uptake of the drug, deliver effective therapeutic doses in a time-delayed fashion, or can target specific organs.Type: GrantFiled: September 21, 2001Date of Patent: March 21, 2006Assignee: Orphan Medical, Inc.Inventors: Mortimer Mamelak, William C. Houghton, Dayton T. Reardan, Brian L. Miller
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Patent number: 6974804Abstract: Acylated cellobiose compounds (CHME) which satisfy the formula; wherein X represents an acyl group (R—CO—) or H, Z represents an acyl group (R?—CO—) or H and not more than a minority of X+Z residues represent H, R represents a saturated or unsaturated, linear or branched chain hydrocarbon residue of 5 to 31 carbon atoms and R? represents a residue, different from R, which is: (i) a saturated or unsaturated, linear or branched chain hydrocarbon residue of 1 to 31 carbon atoms, or (ii) an aromatic hydrocarbon residue, or (iii) a cycloaliphatic hydrocarbon, each optionally substituted. CHME esters are particularly suited to thickening or structuring a water-immiscible liquid, for example, a phase in a cosmetic formulation, such as antiperspirant or deodorant formulations, eg water in oil emulsions and especially translucent ones.Type: GrantFiled: October 17, 2001Date of Patent: December 13, 2005Assignee: Unilever Home & Personal Care USA, division of Conopco, Inc.Inventors: Kevin Ronald Franklin, Andrew Hopkinson, Nicholas Webb, Michael Stephen White
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Patent number: 6969531Abstract: The present invention relates to microspheres comprising hyaluronan derivatized with a bifunctional crosslinker to form microspheres. Methods of making such microspheres, comprising mixing hyaluronic acid and a dihydrazide with a crosslinker in an aqueous solution, adding a solvent and an emulsifying agent to form an emulsion, and lowering the pH of the emulsion to allow intramolecular and intermolecular crosslinking to occur, are also disclosed. The invention also provides for pharmaceutical or cosmetic formulations based on the microspheres described herein, further containing one or more active or cosmetic agents, and methods of using such formulations.Type: GrantFiled: August 26, 2003Date of Patent: November 29, 2005Assignee: Engelhard CorporationInventors: Philip Dehazya, Cheng Lu
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Patent number: 6958394Abstract: A cellulose ester film is disclosed which comprises a polyhydric alcohol ester, which is an ester of one or more kinds of monocarboxylic acids with an aliphatic polyhydric alcohol, wherein the cellulose ester film has a water vapor transmission rate of from 20 to 260 g/m2·24 hours measured under conditions of 25° C. and 90% RH.Type: GrantFiled: April 3, 2002Date of Patent: October 25, 2005Assignee: Konica CorporationInventor: Koichi Saito
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Patent number: 6951934Abstract: The present invention relates to a novel method of chemically preparing functionalized derivatives of ?-(1,3)-glucans, enabling obtaining oligosaccharides which are free or which comprise specific groups such as, for example, sulphate, phosphate, methyl, in pre-defined positions. This method includes a reaction between a glycosyl donor of formula (Ia) or (Ib) and a glycosyl acceptor of formula (II), defined in the claims. Application: Preparation of biologically active compounds which can be used in the agricultural, cosmetic or pharmaceutical fields.Type: GrantFiled: February 2, 2001Date of Patent: October 4, 2005Assignee: Laboratories GoemarInventors: Jean-Claude Yvin, Frank Jamois, Vincent Ferrieres, Daniel Plusquellec
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Patent number: 6939962Abstract: There is described a process for the synthesis of a sucrose-6-ester comprising: (a) reacting a mixture comprising sucrose and a polar aprotic solvent with an organotin-based acylation promoter, while adding a solvent capable of removing water by co-distillation, and removing water by co-distillation, to afford a first reaction mixture which is substantially free from water, followed by (b) adding a carboxylic anhydride to said first reaction mixture to afford a second reaction mixture, and maintaining said second reaction mixture at a temperature and for a period of time sufficient to produce a sucrose-6-ester, characterised in that step (a) is performed at a temperature of from 85 to 125° C. and at a pressure of from 20 to 80 kPa. In the most preferred embodiment, the polar aprotic solvent is DMF, the solvent capable of removing water by co-distillation is cyclohexane, the organotion-based acylation promoter is a 1,3-diacyloxy-1,1,3,3-tetrabutyldistannoxane, and step (a) is performed at approximately 97° C.Type: GrantFiled: July 19, 2001Date of Patent: September 6, 2005Assignee: Tate & Lyle Public Limited CompanyInventors: Jason D. Clark, Richard R. LeMay, Jr.
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Patent number: 6936435Abstract: The production of a purified extracellular bacterial signal called autoinducer-2 is regulated by changes in environmental conditions associated with a shift from a free-living existence to a colonizing or pathogenic existence in a host organism. Autoinducer-2 stimulates LuxQ luminescence genes, and is believed also to stimulate a variety of pathogenesis related genes in the bacterial species that produce it. A new class of bacterial genes is involved in the biosynthesis of autoinducer-2.Type: GrantFiled: September 21, 2001Date of Patent: August 30, 2005Assignees: Princeton University, University Technologies Internat.Inventors: Bonnie L. Bassler, Michael G. Surette