Abstract: An object of the present invention is to provide a compound which, when used for organic semiconductor films in organic thin-film transistors, makes the organic thin-film transistors exhibit a high carrier mobility, a material for an organic thin-film transistor for which the compound is used, a composition for an organic thin-film transistor, an organic thin-film transistor and a method for manufacturing the same, and an organic semiconductor film. An organic thin-film transistor of the present invention contains a compound represented by General Formula (1) in an organic semiconductor film (organic semiconductor layer) thereof.

Abstract: The present invention relates to the fields of chemistry and pharmacy and, in particular, to the production of novel molecular entities: esterane derivatives fused with spirostanes rings, acting upon the Central Nervous Systems (CNS). From diosgenin, a naturally occurring sapogenin, with some subsequent transformations thereof, spirosteroid derivatives of the I-IV general formula can be obtained, with a cyclopentaneperhydrophenantrene nucleus fused to a 25R-spirostanes nucleus. Such molecular entities have an anti-inflammatory and anti-glutamatergic actions that can be used to treat inflammatory, cerebrovascular, neurodegenerative, neuropsychiatric, and neurologic diseases.

Abstract: A series cardenolide derivatives including structure of formula I from the root of Reevesia formosana have provided. In formula (1) and (2), where R3, R5, R10 and R16 are as defined in the specification. The derivatives compounds showed potent cytotoxicity against MCF-7, NCI-H460, and HepG2 cancer cell lines.

Abstract: The present invention relates to a compound of following formula (I): or to a pharmaceutically acceptable salt thereof, as well as to pharmaceutical compositions including same and to the use thereof as a drug, in particular for treating a proliferative disease such as cancer.

Abstract: The invention relates to a process for the preparation of 17-hydroxy-6?,7?;15?,16?-bismethylene-17?-pregn-4-ene-3-one-21-carboxylic acid ?-lactone of formula (I) as well as to key-intermediates for this process.

Abstract: Compositions for the oxidative dyeing of keratin fibers, comprising a medium suitable for dyeing and one or more tricyclic fused 6-5-6 heteroaromatic keratin dyeing compounds having one heteroatom. A method for oxidative dyeing of keratin fibers, comprising applying such compositions in the presence of an oxidizing agent, for a period sufficient to develop the desired coloration.

Abstract: An efficient method for the synthesis of aminosterol compounds such as squalamine and compound 1436 is described. A method of the invention provides for regioselective oxidation and regioselective sulfonation of a fused ring system. The fused ring base can be, for example, a steroid ring base. The aminosterol compounds are effective as, for example, antibiotics, antiangiogenic agents and NHE3 inhibitors.

Abstract: The invention describes 14,17-C.sub.2 -bridged steroids of general formula (I), ##STR1## wherein the various R groups are as defined in the specification, and wherein said steroids are in contrast, with the disclaimed compound, the new compounds are available even after peroral administration with high gestagenic action and are suitable for the production of pharmaceutical agents.

Abstract: A process for the preparation of a compound of the formula ##STR1##

Abstract: 6,6-Ethylenedioxy-22R-hydroxy-2R,3S-isopropylidenedioxy-5.alpha.-cholest-23 -yne, useful as an intermediate for the synthesis of brassinolide.

Abstract: Gamma-lactone derivatives represented by the formula (I) ##STR1## wherein when R.sup.1 is methyl group, R.sup.2 is hydrogen, hydroxyl group or trifluoroacetoxyl group and R.sup.2 may combine with R.sup.3 to form a pi bond; when R.sup.1 combines with R.sup.2 to form methylene group, R.sup.3 is hydrogen; R.sup.4 and R.sup.6 are hydrogen, respectively, or may combine to form a pi bond; R.sup.5 is hydrogen or a protecting group for hydroxyl group; R.sup.7 is hydrogen or straight-chain or branched alkyl group; and St is a steroid nucleus represented by the following formula (B): ##STR2## According to the process of the present invention, the introduction of carbon chains which form polyhydroxylated steroid side chains of brassinolides or the like into steroid nucleus is carried out in one-step with the control of stereochemistry of the contiguous four acyclic chiral centers.

Abstract: Novel .delta.-lactone derivatives which are useful as intermediate for a synthesis of brassinolide, epibrassinolide or bisnorbrassinolide and a process of preparing them are disclosed.According to the process of the present invention, the introduction of carbon chains which form polyhydroxylated steroid side chains of brassinolides or the like into steroid nucleus is carried out in one-step with the control of stereochemistry of the contiguous four acyclic chiral centers.