Abstract: In one aspect, the instant invention provides novel compounds and pharmaceutical compositions useful for treating proliferative diseases such as cancer. In another aspect, the invention provides methods of using certain compounds in the treatment of proliferative diseases such as cancer. In particular, the instant invention provides methods of treating ocular cancer (e.g., retinoblastoma) using intraarterial infusion to administer inventive compounds locally to the eye of a subject with an ocular cancer.
Type:
Application
Filed:
December 1, 2010
Publication date:
February 7, 2013
Applicants:
AnalytiCon Discovery GmbH, Sloan-Kettering Institute for Cancer Research
Inventors:
Hakim Djaballah, Christophe Antczak, David H. Abramson, Horst-Dieter Ambrosi, Karsten Siems, Thorsten Genski