The Lactone Ring Shares At Least Three Ring Members With One Other Cyclo Of The Polycylo Ring System (i.e., Bridged) Patents (Class 540/73)
The lactone ring shares the 11,12,13-positions of the cyclopentanohydrophenanthrene ring system (e.g., 11, 18-lactones, etc.) (Class 540/74)
  • Cucurbitane-triterpenoid compounds, pharmaceutical composition, use and preparation method thereof
    Patent number: 8669244
    Abstract: Disclosed is a cucurbitane-triterpenoid compound for activating estrogen receptor activity, and a pharmaceutical composition, use and preparation method thereof. The cucurbitane-triterpenoid compound is presented as formula (I): wherein a single bond or a double bond is formed between C5 and C10, and a single bond or a double bond is fromed between C8 and C9; when a single bond is formed between C5 and C10, the R1 is oxygen; while a single bond is formed between C8 and C9, R2 is carbonyl group (—C?O), methyl hydroxyl group (—CH(OH)), methyl ketone or methyl dimethoxy group (—CH(OCH3)2); and wherein while R1 is oxygen (—O—) and R2 is carbonyl group (—C?O) or methyl hydroxyl group (—CH(OH)), a single bond is formed between R1 (—O—) and C19 of R2 such that R1 and R2 are formed tetrahydro-2H-pyran-2-one or hemiacetal ring.
    Type: Grant
    Filed: June 30, 2011
    Date of Patent: March 11, 2014
    Assignee: National Taiwan University
    Inventors: Ching-Jang Huang, Yueh-Hsiung Kuo, Chin Hsu
  • Cucurbitane-Triterpenoid Compounds, Pharmaceutical Composition, Use and Preparation Method Thereof
    Publication number: 20120252772
    Abstract: Disclosed is a cucurbitane-triterpenoid compound for activating estrogen receptor activity, and a pharmaceutical composition, use and preparation method thereof. The cucurbitane-triterpenoid compound is presented as formula (I): wherein a single bond or a double bond is formed between C5 and C10, and a single bond or a double bond is fromed between C8 and C9; when a single bond is formed between C5 and C10, the R1 is oxygen; while a single bond is formed between C8 and C9, R2 is carbonyl group (—C?O), methyl hydroxyl group (—CH(OH)), methyl ketone or methyl dimethoxy group (—CH(OCH3)2); and wherein while R1 is oxygen (—O—) and R2 is carbonyl group (—C?O) or methyl hydroxyl group (—CH(OH)), a single bond is formed between R1 (—O—) and C19 of R2 such that R1 and R2 are formed tetrahydro-2H-pyran-2-one or hemiacetal ring.
    Type: Application
    Filed: June 30, 2011
    Publication date: October 4, 2012
    Applicant: NATIONAL TAIWAN UNIVERSITY
    Inventors: CHING-JANG HUANG, YUEH-HSIUNG KUO, CHIN HSU
  • Interlayer insulating film, method for forming the same and polymer composition
    Publication number: 20040033381
    Abstract: The interlayer insulating film of this invention is composed of a polymer in which a first monomer having a substituted acetylenyl group and polymerizable in the three-dimensional direction and a second monomer having a substituted cyclopentanonyl group and polymerizable in the two-dimensional direction are three-dimensionally polymerized.
    Type: Application
    Filed: July 21, 2003
    Publication date: February 19, 2004
    Applicant: MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD.
    Inventor: Nobuo Aoi