Four Ring Hetero Atoms In The Bicyclo Ring System Patents (Class 544/255)
Four ring nitrogens in the bicyclo ring system (Class 544/256)
  • Isoxazolo[3,4-d]pyrimidines
    Patent number: 4202975
    Abstract: Isoxazolo[3,4-d]pyrimidines of the formula ##STR1## wherein R.sup.1, R.sup.2 and R.sup.3, respectively, are hydrogen, lower alkyl, cycloalkyl, or aryl which may be substituted by halogen, are useful as antiinflammatory-analgesic drugs, and the industrially feasible production thereof is provided.
    Type: Grant
    Filed: September 27, 1978
    Date of Patent: May 13, 1980
    Assignee: Takeda Chemical Industries, Ltd.
    Inventors: Ryuji Marumoto, Yoshiyasu Furukawa, Kiyohisa Kawai
  • Pesticidal compounds, compositions and processes
    Patent number: 4189483
    Abstract: A process for combating pests, especially fungi, which comprises applying to plants, seeds, or their loci, an isoxazolo [5,4-d] pyrimidine derivative having the formula: ##STR1## or a salt or optical isomer thereof, wherein R is alkyl or aralkyl, either optionally-substituted; R.sub.2 is hydrogen or alkyl; R.sub.3 is alkyl, aryl, alkylthio, alkanesulphonyl, alkoxy, aryloxy, cyano or optionally-substituted amino.
    Type: Grant
    Filed: March 20, 1978
    Date of Patent: February 19, 1980
    Assignee: Imperial Chemical Industries Limited
    Inventors: Geoffrey D. Snowling, John M. Cox, Raymond A. Burrell, Margaret C. Shephard
  • Oxadiazolopyrimidine derivatives
    Patent number: 4150132
    Abstract: Alkyl or alkoxyalkyl 5-[3,6-dihydro-1(2H)-pyridyl]-2-oxo-2H-[1,2,4]-oxadiazolo-[2,3-a]primidine -7-carbamates, prepared, inter alia, from the corresponding 6-[3,6-dihydro-1(2H)-pyridyl]-2,4-pyrimidine-dicarbamate-3-oxide, are described. The end products are useful in the treatment of vascular-conditioned hypertension or as vasodilators in the case of peripheral blood supply disorders.
    Type: Grant
    Filed: January 27, 1978
    Date of Patent: April 17, 1979
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Jean-Claude Muller, Henri Ramuz
  • Substituted oxadiazolopyrimidines
    Patent number: 4150131
    Abstract: Oxadiazolopyrimidine derivatives of the formula ##STR1## wherein R and R.sub.1 are as hereinafter described, prepared, inter alia, by cyclizing a compound of the formula ##STR2## wherein R and R.sub.1 are as hereinafter described. The end products are useful in the treatment of vascular-conditioned hypertension or as vasodilators in the case of peripheral blood supply disorders.
    Type: Grant
    Filed: January 27, 1978
    Date of Patent: April 17, 1979
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Jean-Claude Muller, Henri Ramuz
  • Isoxazolo[3,4-d]pyrimidines useful as antiinflammatory-analgesic agents
    Patent number: 4129654
    Abstract: Isoxazolo[3,4-d]pyrimidines of the formula ##STR1## wherein R.sup.1, R.sup.2 and R.sup.3 respectively, are hydrogen, lower alkyl, cycloalkyl, or aryl which may be substituted by halogen, are useful as antiinflammatory-analgesic drugs, and the industrially feasible production thereof is provided.
    Type: Grant
    Filed: March 30, 1977
    Date of Patent: December 12, 1978
    Assignee: Takeda Chemical Industries, Ltd.
    Inventors: Ryuji M. Marumoto, Yoshiyasu Furukawa, Kiyohisa Kawai