Having -c(=x)-, Wherein X Is Chalcogen, Bonded Directly To The Bicyclo Ring System Patents (Class 546/120)
  • 2-{[4-(6-Substituted-2-pyrazinyl)- 1-piperazinyl]alkyl}-5-substituted-1,2,4-triazolo[4,3-a]pyridin-3(2H)-one analgesic agents
    Patent number: 4251530
    Abstract: 2-{[4-(6-Substituted-2-pyrazinyl)-1-piperazinyl]alkyl}-5-substituted-1,2,4- triazolo[4,3-a]pyridin-3(2H)ones useful as analgesic agents, having the following formula: ##STR1## wherein p1 n is 2 to 4; R is halo, methyl, methoxy, or CF.sub.3 ; andR.sub.1 is H or methyl;and pharmaceutically acceptable salts thereof.
    Type: Grant
    Filed: February 19, 1980
    Date of Patent: February 17, 1981
    Assignee: Merck & Co., Inc.
    Inventors: Walfred S. Saari, William C. Lumma
  • Substituted 3-alkyl-6-phenyl-1,2,4-triazolo-[4,3-a]pyridines
    Patent number: 4242515
    Abstract: This disclosure describes novel 3-alkyl-6-(substituted-phenyl)-1,2,4-triazolo[4,3-a]pyridines useful as anxiolytic agents.
    Type: Grant
    Filed: March 28, 1979
    Date of Patent: December 30, 1980
    Assignee: American Cyanamid Company
    Inventors: Ronald I. Trust, Jay D. Albright
  • Hydrazino derivatives of 1H-pyrazolo(3,4-b)-pyridine-5-carboxamides
    Patent number: 4153796
    Abstract: Hydrazino derivatives of 1H-pyrazolo[3,4-b]-pyridine-5-carboxamides which have the general formula ##STR1## are useful as ataractic agents, anti-allergy agents or anti-bronchoconstrictor agents.
    Type: Grant
    Filed: July 10, 1978
    Date of Patent: May 8, 1979
    Assignee: E. R. Squibb & Sons, Inc.
    Inventor: Hans Hoehn