Polycyclo Ring System Having The Six-membered Hetero Ring As One Of The Cyclos Patents (Class 546/26)
  • Patent number: 10654862
    Abstract: The present invention in various aspects relates to the synthesis of pyrrole-linked bivalent compounds, including but not limited to norBNI, as well as pharmaceutical compositions comprising the same.
    Type: Grant
    Filed: February 1, 2019
    Date of Patent: May 19, 2020
    Assignee: AVEKSHAN, LLC.
    Inventor: John Cran
  • Patent number: 10532982
    Abstract: Intermediates and methods are provided for the preparation of selected C5aR antagonist compounds.
    Type: Grant
    Filed: March 21, 2019
    Date of Patent: January 14, 2020
    Assignee: ChemoCentryx, Inc.
    Inventors: Pingchen Fan, Jaroslaw Kalisiak, Antoni Krasinski, Rebecca M. Lui, Jay Powers, Sreenivas Punna, Hiroko Tanaka, Penglie Zhang
  • Patent number: 10517858
    Abstract: The present disclosure describes thiazole and pyridine carboxamide derivatives, their compositions and methods of use. The compounds inhibit the activity of the Pim kinases and are useful in the treatment of diseases related to the activity of Pim kinases including, e.g., cancer and other diseases.
    Type: Grant
    Filed: March 11, 2019
    Date of Patent: December 31, 2019
    Assignees: Incyte Holdings Corporation, Incyte Corporation
    Inventors: Chu-Biao Xue, Yun-Long Li, Hao Feng, Ke Zhang
  • Patent number: 10253034
    Abstract: The present invention in various aspects relates to the synthesis of pyrrole-linked bivalent compounds, including but not limited to norBNI, as well as pharmaceutical compositions comprising the same.
    Type: Grant
    Filed: March 18, 2016
    Date of Patent: April 9, 2019
    Assignee: AVEKSHAN, LLC.
    Inventor: John Cran
  • Patent number: 10138253
    Abstract: Disclosed are compounds of Formula I, including pharmaceutically acceptable salts, pharmaceutical compositions comprising the compounds, methods for making the compounds and their use in inhibiting HIV integrase and treating those infected with HIV or AIDS.
    Type: Grant
    Filed: August 10, 2016
    Date of Patent: November 27, 2018
    Assignee: ViiV HEALTHCARE UK (NO.5) LIMITED
    Inventors: John F. Kadow, B. Narasimhulu Naidu, Manoj Patel, Kevin Peese, Zhongyu Wang
  • Patent number: 9849120
    Abstract: The present disclosure describes thiazole and pyridine carboxamide derivatives, their compositions and methods of use. The compounds inhibit the activity of the Pim kinases and are useful in the treatment of diseases related to the activity of Pim kinases including, e.g., cancer and other diseases.
    Type: Grant
    Filed: December 9, 2016
    Date of Patent: December 26, 2017
    Assignees: Incyte Holdings Corporation, Incyte Corporation
    Inventors: Chu-Biao Xue, Yun-Long Li, Hao Feng, Ke Zhang
  • Publication number: 20150073145
    Abstract: A method for the synthesis of carbon-based structures, particularly graphene substructures and ribbons, from oligo- and poly-alkyne starting materials.
    Type: Application
    Filed: November 14, 2014
    Publication date: March 12, 2015
    Inventors: Igor Alabugin, Philip M. Byers
  • Publication number: 20140370652
    Abstract: A new family of tetracene tetracarboxylic diimides is provided. These ones can made by reacting a 9-stannafluorene with a tetrabromo compound including a tetracene tetracarboxylic diimide core. They can be used as n-type electron-transporting materials in electronic devices such as n-channel field-effect transistors. They exhibit excellent air-stability and do not cause parasite injections of holes.
    Type: Application
    Filed: February 10, 2012
    Publication date: December 18, 2014
    Inventors: Zhaohui Wang, Wan Yue
  • Patent number: 8846924
    Abstract: The invention concerns the production of quinoline compounds containing sulfonic acid groups, the said quinoline compounds and their conversion into dyes containing sulfonic acid groups. The dyes according to the invention are used especially to label analytes, for example to label biomolecules.
    Type: Grant
    Filed: March 25, 2011
    Date of Patent: September 30, 2014
    Assignee: Atto-Tec GmbH
    Inventors: Alexander Zilles, Jutta Arden-Jacob, Karl-Heinz Drexhage, Norbert Uwe Kemnitzer, Monika Hamers-Schneider
  • Patent number: 8710225
    Abstract: Disclosed are thiocyanato or isothiocyanato substituted naphthalene diimide and rylene diimide compounds according to formula (I), use of these compounds as n-type semiconductors, methods of preparing these compounds, as well as various compositions, composites, and devices that incorporate these compounds.
    Type: Grant
    Filed: January 10, 2012
    Date of Patent: April 29, 2014
    Assignee: BASF SE
    Inventors: Thomas Gessner, Helmut Reichelt, Nicolle Langer, Anke Schwind
  • Patent number: 8686150
    Abstract: The present invention relates to pyrazolo[3,4-b]pyridine compounds of the formula I, in which R1, R2, R3, R4, R5, R6 and R7 are defined as indicated below. The compounds of the formula I are kinase inhibitors, and are useful for the treatment of diseases associated with diabetes and diabetic complications, such as, diabetic nephropathy, diabetic neuropathy and diabetic retinopathy, for example. The invention furthermore relates to the use of compounds of the formula I, in particular as active ingredients in pharmaceuticals, and pharmaceutical compositions comprising them.
    Type: Grant
    Filed: September 27, 2012
    Date of Patent: April 1, 2014
    Assignee: Sanofi
    Inventors: Stephanie Hachtel, Oliver Plettenburg, Christian Schoenau, Matthias Loehn, Stefania Pfeiffer-Marek, Maria Mendez-Perez, Aimo Kannt, Juergen Dedio, Markus Kohlmann, Alexander Schiffer, Guillaume Begis, Olivier Duclos, Frederic Jeannot
  • Patent number: 8674104
    Abstract: The invention relates to compounds of the formula (I) in which Y1 and Y2 are each O or, respectively, NRa or NRb, where Ra and Rb are each H or organyl; Z1 to Z4 are each O or S; R11 to R14, R21 to R24 are each Cl, F; where 1 or 2 of the R11 to R14, R21 to R24 radicals may also be CN and/or 1 R11 to R14, R21 to R24 radical may be H; and where, when Y1 is NRa, Z1 or Z2 may also be NRc, where Ra and Rc together are a bridging X group having from 2 to 5 atoms; and where, when Y2 is NRb, Z3 or Z4 may also be NRd, where Rb and Rd together are a bridging X group having from 2 to 5 atoms; to a process for preparation thereof, and to their use as emitter materials, charge transport materials or exciton transport materials.
    Type: Grant
    Filed: January 4, 2013
    Date of Patent: March 18, 2014
    Assignee: BASF SE
    Inventors: Martin Koenemann, Gabriele Mattern, Gerd Weber
  • Patent number: 8658665
    Abstract: This invention pertains generally to processes, uses, methods and materials utilizing particular xanthylium compounds, including compounds of formula (I) and (II), as further defined herein. These compounds are useful as drugs, for example, in the treatment of tauopathies, such as Alzheimer's disease.
    Type: Grant
    Filed: December 10, 2009
    Date of Patent: February 25, 2014
    Assignee: WisTa Laboratories Ltd.
    Inventors: Scott Clunas, John Mervyn David Storey, Janet Elizabeth Rickard, David Horsley, Charles Robert Harrington, Claude Michel Wischik
  • Publication number: 20140051860
    Abstract: A nitrogen-containing carbon alloy obtained by baking an organic material having a nitrogen-containing crystalline organic compound having a molecular weight of 60 to 2000, wherein the nitrogen-containing crystalline organic compound excludes a nitrogen-containing metal complex.
    Type: Application
    Filed: October 23, 2013
    Publication date: February 20, 2014
    Applicant: FUJIFILM Corporation
    Inventor: Jun TANABE
  • Patent number: 8586570
    Abstract: Peptidyl sensors comprise a metal-binding peptide and one or two kinase recognition sequences with a hydroxyamino acid that can be phosphorylated in the presence of a kinase.
    Type: Grant
    Filed: April 27, 2011
    Date of Patent: November 19, 2013
    Assignee: Massachusetts Institute of Technology
    Inventors: Barbara Imperiali, Elvedin Lukovic, Dora Carrico-Moniz
  • Patent number: 8580810
    Abstract: The present invention relates to compositions and methods of using free radical scavengers with reduced 1O2 generation. In certain embodiments, these compositions and methods of use relate to fullerene-derived ketolactams and fullerene-derived keto lactam derivatives, fullerene derivatives, and/or fullerenes. In yet other embodiments, the invention relates to cosmetic or dermatological compositions comprising said free radical scavengers with reduced 1O2 generation.
    Type: Grant
    Filed: November 29, 2007
    Date of Patent: November 12, 2013
    Assignee: Solenne BV
    Inventors: David F. Kronholm, Alexander B. Sieval, Jan C. Hummelen
  • Patent number: 8580814
    Abstract: Methods of treating, preventing or managing cancer, including certain leukemias are disclosed. The methods encompass the administration of enantiomerically pure (+)-1,4-dihydro-7-[(3S,4S)-3-methoxy-4-(methylamino)-1-pyrrolidinyl]-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acid. Also provided are methods of treatment using this compound with chemotherapy, radiation therapy, hormonal therapy, biological therapy or immunotherapy. Pharmaceutical compositions and single unit dosage forms suitable for use in the methods are also disclosed.
    Type: Grant
    Filed: September 5, 2006
    Date of Patent: November 12, 2013
    Assignee: Sunesis Pharmaceuticals, Inc.
    Inventors: Daniel C. Adelman, Jeffrey A. Silverman
  • Publication number: 20130207056
    Abstract: Thin layers or films of metal oxides are used as a semiconductor material of solar cells and they are coated with a sensitizer to achieve the high absorption of sunlight. Various dyes have been used as sensitizers in solar cells. Rylene monoimide derivatives are developed as photosensitizers for dye-sensitized solar cells and as photodetectors. The Rylene monoimide derivatives have very good quantum efficiencies, particularly in the NIR region of the absorption spectrum.
    Type: Application
    Filed: February 8, 2013
    Publication date: August 15, 2013
    Inventors: Flavio Luiz Benedito, Ingmar Bruder, Peter Erk, Neil Gregory Pschirer, Robert Send, Klaus Muellen, Henrike Wonneberger, Chen Li
  • Patent number: 8501948
    Abstract: A rylene-based polychromophore of the general formula I in which the variables are each defined as follows: rylene is a radical of the formula which has been functionalized by at least one imide group, ester group or amide group and which may additionally be substituted by aryloxy, arylthio, hetaryloxy and/or hetarylthio; X is a rylenedicarboximide radical which absorbs at a different wavelength from the rylene radical, is bonded to the X radical in the peri-position via Y via a moiety —Y?-A-Y—, is bonded to the rylene radical and may likewise be substituted by aryloxy, arylthio, hetaryloxy and/or hetarylthio; A is a bridging member having at least one aromatic or heteroaromatic radical, the Y or Y and Y? groups being bonded to the aromatic or heteroaromatic radical; Y is a moiety Y? is a moiety where the moieties (i) and (ii) may be part of the ester groups of the rylene radical and the moieties (iii) are part of the imide groups of the rylene radical and the moieties (iv) ar
    Type: Grant
    Filed: July 27, 2006
    Date of Patent: August 6, 2013
    Assignee: BASF Aktiengesellschaft
    Inventor: Martin Konemann
  • Patent number: 8481736
    Abstract: The present invention relates to liquid-crystalline rylene tetracarboxylic acid derivatives, to processes for their preparation and to their use as n-type organic semiconductors for producing organic field-effect transistors and solar cells.
    Type: Grant
    Filed: April 4, 2007
    Date of Patent: July 9, 2013
    Assignees: BASF SE, Max-Planck-Gesellschaft zur Foerderung der Wissenschaften e.V.
    Inventors: Martin Koenemann, Neil Gregory Pschirer, Klaus Muellen, Fabian Nolde, Wojciech Pisula, Sibylle Mueller, Christopher Kohl
  • Patent number: 8471019
    Abstract: A semiconducting layer comprising a non-polymeric quinoid heteroacene compound of the formula (I) wherein X stands for O, S or NR, each of R, R1, R2, R3, R4, R5, R6, R7, R8 being independently selected from hydrogen and an organic residue, or 2 or more thereof together forming one or more annealed rings, which may be substituted or unsubstituted, carbocyclic or helerocyclic, aromatic, quinoid or aliphatic, may be used e.g. for the manufacture of a diode, an organic field effect transistor, an organic thin film transistor, or a device containing a diode and/or an organic field effect transistor and/or organic thin film transistor.
    Type: Grant
    Filed: April 4, 2007
    Date of Patent: June 25, 2013
    Assignee: BASF SE
    Inventors: Ulrich Berens, Arno Stassen, Beat Schmidhalter, Wolfgang Kalb, Frank Bienewald
  • Publication number: 20130131015
    Abstract: The present invention provides active compounds for modulating nicotinic acetylcholine receptors and methods of making the same. The methods of preparing the active compounds utilize different intermediate compounds.
    Type: Application
    Filed: January 18, 2013
    Publication date: May 23, 2013
    Inventor: North Carolina State University
  • Patent number: 8440673
    Abstract: Compounds of the formula I: or a pharmaceutically acceptable salt thereof, wherein, R1 is optionally substituted pyrazolyl, and R2, R3, R4, R5, R6, R7 and R8 are as defined herein. Also disclosed are methods of using the compounds for treating diseases associated with P2X3 and/or a P2X2/3 receptor antagonists and methods of making the compounds.
    Type: Grant
    Filed: December 17, 2008
    Date of Patent: May 14, 2013
    Assignee: Roche Palo Alto LLC
    Inventors: Li Chen, Michael Patrick Dillon, Lichun Feng, Ronald Charles Hawley, Minmin Yang
  • Publication number: 20130109858
    Abstract: A core-expanded perylene diimide compound having general formula A useful as a fluorescent dye is synthesized:
    Type: Application
    Filed: July 16, 2010
    Publication date: May 2, 2013
    Applicant: NITTO DENKO CORPORATION
    Inventor: Nobukazu Negishi
  • Patent number: 8399669
    Abstract: The present invention relates to pentarylenetetracarboximides of the formula (I) or (Ia) or mixtures thereof to processes for preparation thereof, and to the precursors and use thereof.
    Type: Grant
    Filed: April 21, 2009
    Date of Patent: March 19, 2013
    Assignee: BASF SE
    Inventors: Jianqiang Qu, Neil Gregory Pschirer
  • Patent number: 8362030
    Abstract: The present invention relates to compounds of formula (I) and pharmaceutically acceptable salts or tautomers thereof which are inhibitors of poly(ADP-ribose)polymerase (PARP) and thus useful for the treatment of cancer, inflammatory diseases, reperfusion injuries, ischaemic conditions, stroke, renal failure, cardiovascular diseases, vascular diseases other than cardiovascular diseases, diabetes mellitus, neurodegenerative diseases, retroviral infections, retinal damage, skin senescence and UV-induced skin damage, and as chemo- or radiosensitizers for cancer treatment.
    Type: Grant
    Filed: March 13, 2009
    Date of Patent: January 29, 2013
    Assignee: Istituto di Ricerche di Biologia Molecolare P. Angeletti S.R.L.
    Inventors: Raffaele Ingenito, Philip Jones, Laura Llauger Bufi, Jesus Maria Ontoria Ontoria, Rita Scarpelli
  • Patent number: 8350035
    Abstract: The present invention relates to fluorinated rylenetetracarboxylic acid derivatives, to a process for their preparation and to their use, especially as n-type semiconductors.
    Type: Grant
    Filed: February 16, 2007
    Date of Patent: January 8, 2013
    Assignee: BASF Aktiengesellschaft
    Inventors: Martin Koenemann, Peter Osswald, Ruediger Schmidt, Frank Wuerthner
  • Patent number: 8334029
    Abstract: The invention provides materials and methods for making anisotropic solids which may be in the form of films, layers, shaped elements, and other shaped articles. The methods provide anisotropic solids without the need for rolling, rubbing, or stretching to impart orientational alignment of the molecules of the solid. The methods employ organic or organometallic compounds which are soluble orienting molecules. The solvent or solvent system must be sufficiently volatile to be removed without disruption of the molecular orientation. The soluble orienting molecules include those containing one or more hydrophilic and/or ionic groups and the solvent or solvent system can be a polar organic solvent or solvent system or an aqueous solvent or solvent system. The invention also provides novel compounds having quaterrylene, perylene and naphthalene ring systems carrying one or more hydrophilic and/or ionic groups.
    Type: Grant
    Filed: April 4, 2011
    Date of Patent: December 18, 2012
    Assignee: Board of Regents of the Nevada System of Higher Education, on behalf of the University of Nevada, Reno
    Inventors: Suk-Wah Tam-Chang, Sean M. Casey, Isaac K. Iverson, Wonewoo Seo
  • Patent number: 8299091
    Abstract: The invention relates to the compound N-(2-oxo-2-propoxyethyl)-?-phenyl-D-phenyl-alanyl-N-[(1-amino-6-iso-quinolinyl)methyl]-L-prolinamide or a pharmaceutically acceptable salt thereof, to a pharmaceutical composition comprising said compound, as well as to the use of the compound for the manufacture of a medicament for treating or for preventing thrombin mediated diseases.
    Type: Grant
    Filed: August 6, 2007
    Date of Patent: October 30, 2012
    Assignee: MSD Oss B.V.
    Inventors: Robert Gilfillan, David Jonathan Bennett
  • Publication number: 20120264900
    Abstract: Disclosed are new semiconductor materials prepared from thienocoronene-imide-based small molecule and/or polymeric compounds. Such compounds can exhibit high carrier mobility and/or good current modulation characteristics. In addition, the compounds of the present teachings can possess certain processing advantages such as solution-processability and/or good stability at ambient conditions.
    Type: Application
    Filed: April 27, 2011
    Publication date: October 18, 2012
    Inventors: Hakan Usta, Zhihua Chen, Antonio Facchetti
  • Publication number: 20120234380
    Abstract: A terrylene compound of formula I: wherein R1 to R4 are each independently an unsubstituted or substituted alkyl, aryl, thiophenyl or oligothiophenyl group, or a hydrogen atom. Two adjacent radicals selected from R1 to R4, together with the carbon atoms of the benzene ring to which they are bonded, may also form a fused ring system having 1 to 8 additional rings. With the carbon atoms to which it is bonded, A forms a fused monocyclic, dicyclic, tricyclic, tetracyclic, pentacyclic or hexacyclic ring system which optionally contains one or more independently selected substituents. A process for preparing the terrylene compound. An organic solar cell with a photoactive region including at least one organic donor material in contact with at least one organic acceptor material, the donor material and the acceptor material forming a donor-acceptor heterojunction, and the photoactive region including at least one such terrylene compound.
    Type: Application
    Filed: March 13, 2012
    Publication date: September 20, 2012
    Applicant: BASF SE
    Inventors: Martin Könemann, Gabriele Mattern, Jae Hyung Hwang, Regina Höh, Christian Dörr, Junichi Tanabe
  • Patent number: 8269008
    Abstract: The present invention relates to novel compounds capable of modulating the stability and/or activity of hypoxia inducible factor (HIF) by inhibiting the activity of at least one HIF hydroxylase enzyme.
    Type: Grant
    Filed: December 2, 2008
    Date of Patent: September 18, 2012
    Assignee: FibroGen, Inc.
    Inventors: Michael P. Arend, Heng Cheng, Lee A. Flippin, Danny Ng, Eric D. Turtle, Min Wu
  • Patent number: 8258149
    Abstract: The invention provides novel compounds of formula (I) or a pharmaceutically acceptable salt thereof, wherein R1 to R7 are as described herein, compositions including the compounds and methods of preparing and using the compounds.
    Type: Grant
    Filed: April 30, 2010
    Date of Patent: September 4, 2012
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Li Chen, Lichun Feng, Yongguo Li, Guolong Wu
  • Publication number: 20120186648
    Abstract: A photovoltaic device (10) having a coaxial molecular stack (12) for transferring photocurrent is disclosed. The device (10) comprises a plurality of coaxial molecular stacks (12) located between and oriented substantially perpendicular to first (14) and second (16) electrodes to provide charge transport of photocurrent through each coaxial molecular stack (12) in the photovoltaic device (10). Each coaxial molecular stack (12) comprises a plurality of ?-conjugated planar supramolecules (18) stackable through columnar self assembly to form the coaxial molecular stack (12). Each supramolecule (18) is comprised of a ?-conjugated hub (20) covalently appended to multiple copies of an electron acceptor spoke (22) to form an outer n-channel with a coaxial inner p-channel.
    Type: Application
    Filed: August 9, 2010
    Publication date: July 26, 2012
    Inventors: Ling Zang, Yanke Che
  • Patent number: 8217041
    Abstract: The present invention makes reference to new indene derivatives with general formula (I), as well as to their preparation procedures, their application as medicament and the pharmaceutical compositions containing them. The new compounds of formula (I) show affinity for 5-HT6 receptors and are, therefore, effective for treating diseases mediated by these receptors.
    Type: Grant
    Filed: November 7, 2006
    Date of Patent: July 10, 2012
    Assignee: Laboratories del Sr. Esteve, S.A.
    Inventors: Maria de las Ermitas Alcalde-Pais, Jordi Frigola-Constansa, Joerg Holenz, Ramon Merce-Vidal, Maria de les Neus Mesquida-Estevez, Sara Lopez-Perez
  • Patent number: 8163749
    Abstract: The present invention provides compounds of Formula (I): or a stereoisomer, tautomer, pharmaceutically acceptable salt or solvate form thereof, wherein the variables A, B, R3 and R11 are as defined herein. The compounds of Formula (I) are useful as selective inhibitors of serine protease enzymes of the coagulation cascade and/or contact activation system; for example thrombin, factor Xa, factor XIa, factor IXa, factor VIIa and/or plasma kallikrein. In particular, it relates to compounds that are selective factor XIa inhibitors or dual inhibitors of fXIa and plasma kallikrein. This invention also relates to pharmaceutical compositions comprising these compounds and methods of treating thromboembolic and/or inflammatory disorders using the same.
    Type: Grant
    Filed: December 13, 2006
    Date of Patent: April 24, 2012
    Assignee: Bristol-Myers Squibb Company
    Inventor: James R. Corte
  • Patent number: 8158376
    Abstract: This invention relates to fluorescent probes for identification of compounds binding to protein kinases, for measurement of the affinity of inhibitors of protein kinases, and determination of the active concentration of protein kinases binding to the probe. Bisubstrate-analog character of the probe enables the simultaneous evaluation of inhibitors targeted to both ATP binding site and/or substrate protein/peptide binding domain of the kinase. High affinity of the probe (Kd=1.0 nM towards cAMP-dependent protein kinase) affords the application of the enzymes at low concentration which leads to the substantial decrease of the consumption of the kinase. Due to the ability of the conjugates of oligo(D-arginine) with a ATP binding site targeted inhibitors of this invention to bind with high affinity to a wide spectrum of (basophilic) kinases, a single Fluorescent probe is applicable for assessment of inhibitory potency of compounds towards a great number of protein kinases.
    Type: Grant
    Filed: August 14, 2007
    Date of Patent: April 17, 2012
    Assignee: University of Tartu
    Inventors: Asko Uri, Erki Enkvist, Indrek Viil, Darja Lavögina, Gerda-Johanna Raidaru, Kaido Viht
  • Patent number: 8115001
    Abstract: The invention relates to a laminar microporous crystalline zeolite material known as ITQ-30 which, as when synthesized, has a chemical composition in the anhydrous state with the following molar relations: x (M1/n XO2):y YO2:SiO2:z R, wherein: x represents a value less than 0.1, which can be equal to zero; y has a value of less than 0.1, which can be equal to zero; z has a value of less than 0.1; M is selected from among H+, NH4+, one or more +n inorganic cations and combinations of same; X represents one or more +3 oxidation state chemical elements; Y represents one or more +4 oxidation state chemical elements; and R represents one or more organic compounds. The invention also relates to the method of preparing said zeolite, involving the use of one or more organic additives in a reaction mixture which is crystallized by means of heating, and to the use thereof in processes for the separation and transformation of organic compounds.
    Type: Grant
    Filed: May 25, 2005
    Date of Patent: February 14, 2012
    Assignees: Consejo Superior De Investigaciones Cientificas, Universidad Politecnica De Valencia
    Inventors: Avelino Corma Canos, María José Díaz Cabañas
  • Patent number: 8088922
    Abstract: Dibenzorylenetetracarboximides of the general formula I in which the variables are each defined as follows: R? are identical or different radicals: hydrogen; optionally substituted aryloxy, arylthio, hetaryloxy or hetarylthio; R are identical or different radicals: hydrogen; optionally substituted C1-C30-alkyl, C3-C8-cycloalkyl, aryl or hetaryl; m, n are each independently 0 or 1.
    Type: Grant
    Filed: May 29, 2007
    Date of Patent: January 3, 2012
    Assignees: BASF Aktiengesellschaft, Max-Planck-Gesellschaft zur Foerderung der Wissenschaften e.V.
    Inventors: Martin Koenemann, Arno Boehm, Yuri Avlasevic, Klaus Muellen
  • Patent number: 8084610
    Abstract: Improved compositions have been developed which are selectively sequestered in acidic areas of tumors. When the compositions contain a radioisotope effective to report the presence of the composition, the compositions are useful for detecting tumors. When the compositions contain radioisotopes effective to kill cells, the compositions are useful for treating tumors. Methods for detecting and treating tumors with such compositions are also disclosed.
    Type: Grant
    Filed: June 7, 2006
    Date of Patent: December 27, 2011
    Inventor: James Edward Summerton
  • Patent number: 8083971
    Abstract: The invention relates to compounds of general formula (I) and to the use thereof as active materials in solar cells and photodetectors. The variables in formula (I) are defined in the specification. Formula (I) also has the following example.
    Type: Grant
    Filed: July 21, 2008
    Date of Patent: December 27, 2011
    Assignee: BASF SE
    Inventors: Neil Gregory Pschirer, Ruediger Sens
  • Publication number: 20110308592
    Abstract: The present invention relates to an organic solar cell with a photoactive region which comprises at least one organic donor material in contact with at least one organic acceptor material, wherein the donor material and the acceptor material form a donor-acceptor heterojunction and wherein the photoactive region comprises at least one substituted perylene.
    Type: Application
    Filed: June 17, 2011
    Publication date: December 22, 2011
    Applicant: BASF SE
    Inventors: Martin KÖNEMANN, Jae Hyung HWANG, Gabriele MATTERN, Regina HÖH, Christian DÖRR
  • Patent number: 8071775
    Abstract: Rylene derivatives of the general formula I in which the variables are each defined as follows: Rylene is a polycyclic conjugated ring system which comprises at least one perylene unit may comprise heteroatoms as ring atoms, may be functionalized by moieties comprising —CO— groups and/or may bear further substituents other than the A radicals; A is a radical of the formula X is oxygen or sulfur; R are identical or different radicals: optionally substituted alkyl, cycloalkyl, aryl, hetaryl, —U-aryl where U is an —O—, —S—, —NR2—, —CO—, —SO— or —SO2— moiety, or C1-C12-alkoxy, C1-C6-alkylthio, —C?CR2, —CR2?CR22, hydroxy, mercapto, halogen, cyano, nitro, —NR3R4, —NR3COR4, —CONR3R4, —SO2NR3R4, —COOR3 or —SO3R3; R? are identical or different radicals: hydrogen or one of the R radicals; R2 is hydrogen or alkyl, where the R2 radicals may be the same or different when they occur more than once; R3, R4 are each independently hydrogen; optionally substituted alkyl, aryl or hetaryl; n is from 1 to
    Type: Grant
    Filed: July 6, 2006
    Date of Patent: December 6, 2011
    Assignee: BASF Aktiengesellschaft
    Inventors: Martin Koenemann, Arno Boehm, Neil Gregory Pschirer, Jianqiang Qu, Gabriele Mattern
  • Patent number: 8072137
    Abstract: To provide a material for an organic light emitting device showing a light emission hue with an extremely good purity and outputting light having high luminance and a long lifetime with high efficiency, the present invention relates to a fused heterocyclic compound having at least one partial structure represented by the following general formula [1].
    Type: Grant
    Filed: July 31, 2007
    Date of Patent: December 6, 2011
    Assignee: Canon Kabushiki Kaisha
    Inventors: Hiroki Ohrui, Shinjiro Okada, Akihiro Senoo, Naoki Yamada, Masanori Muratsubaki
  • Patent number: 8058457
    Abstract: A star-shaped oligothiophene-arylene derivative in which an oligothiophene having p-type semiconductor characteristics is bonded to an arylene having n-type semiconductor characteristics positioned in the central moiety of the molecule and forms a star shape with the arylene, thereby simultaneously exhibiting both p-type and n-type semiconductor characteristics. Further, an organic thin film transistor using the oligothiophene-arylene derivative. The star-shaped oligothiophene-arylene derivative can be spin-coated at room temperature, leading to the fabrication of organic thin film transistors simultaneously satisfying the requirements of high charge carrier mobility and low off-state leakage current.
    Type: Grant
    Filed: February 17, 2010
    Date of Patent: November 15, 2011
    Assignee: Samsung Electronics Co., Ltd.
    Inventors: Kook Min Han, Eun Jeong Jeong, Chang Ju Kim, Eun Kyung Lee
  • Patent number: 8052899
    Abstract: The present invention relates to heptarylene- and octarylenetetracarboximides of the general formula (I) to precursors thereof or mixtures thereof, and to processes for their preparation and to their use.
    Type: Grant
    Filed: October 25, 2007
    Date of Patent: November 8, 2011
    Assignees: BASF Aktiengesellschaft, Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V.
    Inventors: Jianqiang Qu, Neil Gregory Pschirer, Martin Koenemann, Klaus Muellen, Yuri Avlasevic
  • Publication number: 20110257400
    Abstract: The invention provides materials and methods for making anisotropic solids which may be in the form of films, layers, shaped elements, and other shaped articles. The methods provide anisotropic solids without the need for rolling, rubbing, or stretching to impart orientational alignment of the molecules of the solid. The methods employ organic or organometallic compounds which are soluble orienting molecules. The solvent or solvent system must be sufficiently volatile to be removed without disruption of the molecular orientation. The soluble orienting molecules include those containing one or more hydrophilic and/or ionic groups and the solvent or solvent system can be a polar organic solvent or solvent system or an aqueous solvent or solvent system. The invention also provides novel compounds having quaterrylene, perylene and naphthalene ring systems carrying one or more hydrophilic and/or ionic groups.
    Type: Application
    Filed: April 4, 2011
    Publication date: October 20, 2011
    Inventors: Travis D. Carson, Sean M. Casey, Isaac K. Iverson, Wonewoo Seo, Suk-Wah Tam-Chang
  • Patent number: 8030346
    Abstract: Compounds of Formula I are useful inhibitors of HIF prolyl hydroxylases. Compounds of Formula I have the following structure: where the definitions of the variables are provided herein.
    Type: Grant
    Filed: April 29, 2008
    Date of Patent: October 4, 2011
    Assignee: Amgen Inc.
    Inventors: Jennifer R. Allen, Roland Burli, Michael J. Frohn, Randall W. Hungate, Susana C. Neira, Anthony B. Reed
  • Patent number: 7989583
    Abstract: The dimerization or polymerization reaction of pyridinic alcohols is carried out in order to produce novel products. The process is carried out in the absence or presence of some solvent, during the process of the current invention, temperature may be or may be not used as catalyst, in the process of the current invention the reaction may be or may not be catalyzed by the presence of a catalyst (acid or base), the resultant products can be produced and separated in an easy way, in the process of the current invention starting from pyridinic alcohols the resultant ethenediols can be produced by a single step reaction. The pyridinemethanol derivatives used as starting compounds, do not oxidize as easily and their handling is easier than that of other compounds. The products produced with etheneidol parts can be used as antioxidants due to their capacity to act as free radicals scavengers.
    Type: Grant
    Filed: July 31, 2008
    Date of Patent: August 2, 2011
    Assignee: Benemerita Universidad Autonoma de Puebla
    Inventors: Maria Judith Percino Zacarias, Victor Manuel Chapela Castanares, Berenice Herrera De La Luz
  • Publication number: 20110165691
    Abstract: Novel mono-azide substituted rylene-imide derivatives, their use in methods for the detection of analytes and reagents kits for the detection of analytes comprising said novel mono-azide substituted rylene-imide derivatives.
    Type: Application
    Filed: January 14, 2011
    Publication date: July 7, 2011
    Applicant: BASF SE
    Inventors: Thomas Geßner, Helmut Reichelt, Ingo Münster, Martin Könemann, Neil Gregory Pschirer, Jian Qiang Qu, Rüdiger Sens, Anja Schwögler, Antonio Manetto