Nonacyclo Ring System Having The Six-membered Hetero Ring As One Of The Cyclos Patents (Class 546/28)
  • Patent number: 11952495
    Abstract: The present disclosure provides for compounds of Formula (I), its corresponding compounds of Formula (II) or salts thereof and their use as fluorogenic pH sensors.
    Type: Grant
    Filed: October 11, 2021
    Date of Patent: April 9, 2024
    Assignee: Life Technologies Corporation
    Inventors: Yi-Zhen Hu, Aimei Chen, Daniel Beacham, Chrisgen Vonnegut, Krishnamurthy Nacharaju
  • Patent number: 11603370
    Abstract: Thermally assisted delayed fluorescent materials with triad-type materials for use in full color displays and lighting applications with the following generic structures are provided:
    Type: Grant
    Filed: October 9, 2020
    Date of Patent: March 14, 2023
    Assignee: Arizona Board of Regents on Behalf of Arizona State University
    Inventor: Jian Li
  • Patent number: 10851106
    Abstract: Thermally assisted delayed fluorescent materials with triad-type materials for use in full color displays and lighting applications with the following generic structures are provided:
    Type: Grant
    Filed: August 27, 2019
    Date of Patent: December 1, 2020
    Assignee: ARIZONA BOARD OF REGENTS, ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY
    Inventor: Jian Li
  • Patent number: 10597407
    Abstract: The present disclosure provides an energy storage molecular material, crystal dielectric layer and capacitor which may solve a problem of the further increase of volumetric and mass density of reserved energy associated with some energy storage devices, and at the same time reduce cost of materials.
    Type: Grant
    Filed: April 3, 2018
    Date of Patent: March 24, 2020
    Assignee: CAPACITOR SCIENCES INCORPORATED
    Inventor: Pavel Lazarev
  • Patent number: 9932358
    Abstract: The present disclosure provides an energy storage molecular material, crystal dielectric layer and capacitor which may solve a problem of the further increase of volumetric and mass density of reserved energy associated with some energy storage devices, and at the same time reduce cost of materials.
    Type: Grant
    Filed: May 21, 2015
    Date of Patent: April 3, 2018
    Assignee: CAPACITOR SCIENCE INCORPORATED
    Inventor: Pavel Ivan Lazarev
  • Patent number: 9136483
    Abstract: A regioselective synthesis of an azacoronene fused with two peripheral thiophene groups has been realized through a concise synthetic route. The resulting thienoazacoronene (TAC) derivatives show high degree of self-organization in solution, in single crystals, in the bulk, and in spuncast thin films. Spuncast thin film field-effect transistors of the TACs exhibited mobilities up to 0.028 cm2V?1 S?1, which is among the top field effect mobilities for solution processed discotic materials. Organic photovoltaic devices using TAC-containing conjugated polymers as the donor material exhibited a high open-circuit voltage of 0.89 V, which was ascribable to TAC's low-lying highest occupied molecular orbital energy level.
    Type: Grant
    Filed: April 16, 2015
    Date of Patent: September 15, 2015
    Assignee: The Regents of the University of California
    Inventors: Yi Liu, Bo He
  • Publication number: 20140356873
    Abstract: The present invention describes novel dyes, including coumarins, rhodamines, and rhodols that incorporate additional fused aromatic rings. The dyes of the invention absorb at a longer wavelength than structurally similar dyes that do not possess the fused aromatic rings. Many of the dyes of the invention are useful fluorescent dyes. The invention includes chemically reactive dyes, dye-conjugates, and the use of such dyes in staining samples and detecting ligands or other analytes.
    Type: Application
    Filed: August 18, 2014
    Publication date: December 4, 2014
    Inventors: Zhenjun DIWU, Jixiang LIU, Kyle GEE
  • Publication number: 20140179017
    Abstract: Novel tetracationic cyclophanes incorporating ?-electron poor organic compounds into their ring structures, as well as methods of making the cyclophanes, are provided. The cyclophanes are able to form electron donor-acceptor complexes with a variety of polyaromatic hydrocarbons (PAHs) ranging in size, shape, and electron density. Also provided are methods of using the cyclophanes in the sequestration of PAHs in liquid or gaseous samples, the separation of PAHs from liquid or gaseous samples, the detection of PAHs in liquid samples, and the exfoliation of graphene via pseudopolyrotaxane formation.
    Type: Application
    Filed: December 20, 2013
    Publication date: June 26, 2014
    Inventors: J. Fraser Stoddart, Jonathan C. Barnes, Michal Jurícek
  • Publication number: 20130026422
    Abstract: The present invention relates to a compound according to formula (I), to the use thereof in an electronic device and to an electronic device which comprises one or more compounds according to formula (I).
    Type: Application
    Filed: March 16, 2011
    Publication date: January 31, 2013
    Applicant: Merck Patent GmbH
    Inventors: Amir Hossain Parham, Christof Pflumm
  • Publication number: 20120315661
    Abstract: The present invention describes novel dyes, including coumarins, rhodamines, and rhodols that incorporate additional fused aromatic rings. The dyes of the invention absorb at a longer wavelength than structurally similar dyes that do not possess the fused aromatic rings. Many of the dyes of the invention are useful fluorescent dyes. The invention includes chemically reactive dyes, dye-conjugates, and the use of such dyes in staining samples and detecting ligands or other analytes.
    Type: Application
    Filed: May 14, 2012
    Publication date: December 13, 2012
    Applicant: LIFE TECHNOLOGIES CORPORATION
    Inventors: Zhenjun DIWU, Jixiang LIU, Kyle GEE
  • Publication number: 20120186648
    Abstract: A photovoltaic device (10) having a coaxial molecular stack (12) for transferring photocurrent is disclosed. The device (10) comprises a plurality of coaxial molecular stacks (12) located between and oriented substantially perpendicular to first (14) and second (16) electrodes to provide charge transport of photocurrent through each coaxial molecular stack (12) in the photovoltaic device (10). Each coaxial molecular stack (12) comprises a plurality of ?-conjugated planar supramolecules (18) stackable through columnar self assembly to form the coaxial molecular stack (12). Each supramolecule (18) is comprised of a ?-conjugated hub (20) covalently appended to multiple copies of an electron acceptor spoke (22) to form an outer n-channel with a coaxial inner p-channel.
    Type: Application
    Filed: August 9, 2010
    Publication date: July 26, 2012
    Inventors: Ling Zang, Yanke Che
  • Patent number: 8134017
    Abstract: A compound represented by the following formula (1) or (2):
    Type: Grant
    Filed: December 2, 2010
    Date of Patent: March 13, 2012
    Assignee: Riken
    Inventors: Shinichiro Kamino, Shuichi Enomoto
  • Publication number: 20110308592
    Abstract: The present invention relates to an organic solar cell with a photoactive region which comprises at least one organic donor material in contact with at least one organic acceptor material, wherein the donor material and the acceptor material form a donor-acceptor heterojunction and wherein the photoactive region comprises at least one substituted perylene.
    Type: Application
    Filed: June 17, 2011
    Publication date: December 22, 2011
    Applicant: BASF SE
    Inventors: Martin KÖNEMANN, Jae Hyung HWANG, Gabriele MATTERN, Regina HÖH, Christian DÖRR
  • Publication number: 20110306603
    Abstract: 8-Substituted-2,6-methano-3-benzazocines of general structure are useful as analgesics, anti-diarrheal agents, anticonvulsants, antitussives and anti-addiction medications.
    Type: Application
    Filed: August 23, 2011
    Publication date: December 15, 2011
    Applicant: RENSSELAER POLYTECHNIC INSTITUTE
    Inventor: Mark P. Wentland
  • Publication number: 20110266533
    Abstract: The present invention relates to compounds of the formula (1) and to the use thereof in organic electronic devices, and to organic electronic devices which comprise compounds of the formula (1), preferably as hole-transport materials and/or as emitting materials.
    Type: Application
    Filed: December 22, 2009
    Publication date: November 3, 2011
    Applicant: Merck Patent GmbH
    Inventors: Arne Buesing, Holger Heil, Philipp Stoessel, Amir Hossain Parham, Rocco Fortte, Jonas Valentin Kroeber
  • Patent number: 8044203
    Abstract: This invention relates to the functionalized cyanine dyes and more particularly, to the synthesis of chiral 3-substituted 2,3?-dimethyl-3H-indole and its derivatives as intermediates for preparation of cyanine dyes, to methods of preparing these dyes and the dyes so prepared.
    Type: Grant
    Filed: October 13, 2009
    Date of Patent: October 25, 2011
    Assignees: Carnegie Mellon University, GE Healthcare UK Limited
    Inventors: Ratnaker B. Mujumdar, Richard Martin West
  • Patent number: 8039625
    Abstract: Briefly described, embodiments of this disclosure include coronene charge-transport materials, methods of forming coronene charge-transport materials, and methods of using the coronene charge-transport materials.
    Type: Grant
    Filed: February 28, 2006
    Date of Patent: October 18, 2011
    Assignee: Georgia Tech Research Corporation
    Inventors: Seth Marder, Zesheng An, Jungsheng Yu, Bernard Kippelen
  • Publication number: 20110155247
    Abstract: Disclosed are thionated fused-ring (aromatic) imides and diimides that can exhibit desirable electronic properties and can possess processing advantages including solution-processability and/or good stability at ambient conditions.
    Type: Application
    Filed: December 29, 2010
    Publication date: June 30, 2011
    Inventors: Jordan Quinn, Yan Zheng, Zhihua Chen, Hakan Usta, Christopher Newman, He Yan, Antonio Facchetti
  • Publication number: 20110149393
    Abstract: This invention relates to polycyclic organic compounds of a general structural formula (I): wherein Y is a predominantly planar polycyclic system being at least partially aromatic, W1, W2, and W3 are different groups providing solubility in an organic solvent, and sum n1+n2+n3 is 1, 2, 3, 4, 5, 6, 7, 8, 9 or 10, which are capable of forming supramolecular structures in a wide range of organic solvents, and which are capable of absorbing electromagnetic radiation in at least one subrange of the visible spectral range.
    Type: Application
    Filed: March 4, 2009
    Publication date: June 23, 2011
    Applicant: Crysoptic KK
    Inventors: Alexey Nokel, Pavel I. Lazarev
  • Publication number: 20110079733
    Abstract: The reaction of aromatic nitriles with perylenetetracarboximides affords colorants which fluoresce strongly in the long-wave region and are of the formula in which one pair Q1 and Q2 or one pair Q2 and Q3, and optionally from 0 to 3 pairs Q3 and Q4, Q5 and Q6, Q6 and Q7 and/or Q7 and Q8, in each case in pairs, together form a heterocyclic ring the remaining Q1, Q4, Q5 and Q8 which do not form a heterocyclic ring are each hydrogen, and the remaining Q3, Q6 and Q7 which do not form a heterocyclic ring are each independently R5 or R6. R1 to R8 are each H, CN, halogen or optionally mono- or polysubstituted hydrocarbon groups. Establishing a suitable pH achieves a large Stokes shift in these colorants via the ESPT mechanism.
    Type: Application
    Filed: December 12, 2008
    Publication date: April 7, 2011
    Applicant: BASF SE
    Inventors: Heinz Langhals, Simon Kinzel, Andreas Obermeier
  • Publication number: 20110076779
    Abstract: Compounds of the general formula (I) and compounds of the general formula (II) Use of compounds (I) or (II) as visible or invisible markers, for staining materials, in the laser welding of materials, for detecting bases, acids or pH changes, as a dispersing assistant, pigment additive for organic pigments and intermediates for the production of pigment additives, in heat management or energy management, in photovoltaics or in optical data storage.
    Type: Application
    Filed: May 20, 2009
    Publication date: March 31, 2011
    Applicants: BASF SE, Max-Planck-Gesellschaft Zur Foerd Der Wissen. E.V.
    Inventors: Thomas Gessner, Helmut Reichelt, Klaus Muellen, Zhihong Liu, Chen Li
  • Publication number: 20110064892
    Abstract: This invention relates to polycyclic organic compounds of general structural formula (I): wherein Y is a predominantly planar polycyclic system being at least partially aromatic, W1, W2, and W3 are different groups providing solubility in an organic solvent, and sum (n1+n2+n3) is 1, 2, 3, 4, 5, 6, 7 or 8. The polycyclic organic compounds are substantially transparent for electromagnetic radiation in the visible spectral range and are capable of forming supramolecules in the organic solvent.
    Type: Application
    Filed: March 4, 2009
    Publication date: March 17, 2011
    Inventors: Alexey Nokel, Pavel I. Lazarev
  • Publication number: 20110042651
    Abstract: The present invention relates to liquid-crystalline rylenetetracarboxylic acid derivatives, to processes for their preparation and to their use as n-type organic semiconductors for producing organic field-effect transistors and solar cells.
    Type: Application
    Filed: April 4, 2007
    Publication date: February 24, 2011
    Applicants: Basf Se, Max-Planck-Gesellschaft Zur Foerd Der Wissen. E.V.
    Inventors: Martin Koenemann, Neil Gregory Pschirer, Klaus Muellen, Fabian Nolde, Wojciech Pisula, Sibylle Mueller, Christopher Kohl
  • Patent number: 7892345
    Abstract: The invention accordingly relates to a method for preparing transparent C.I. Pigment Violet 23 by salt kneading a Pigment Violet 23-crude in the presence of a crystalline salt and an organic liquid. Said method is characterized in that the organic liquid is propylene carbonate.
    Type: Grant
    Filed: February 28, 2008
    Date of Patent: February 22, 2011
    Assignee: Clariant Finance (BVI) Limited
    Inventors: Wolfgang Hoyer, Leonhard Unverdorben
  • Publication number: 20110039989
    Abstract: The present invention relates to pentarylenetetracarboximides of the formula (I) or (Ia) or mixtures thereof to processes for preparation thereof, and to the precursors and use thereof.
    Type: Application
    Filed: April 21, 2009
    Publication date: February 17, 2011
    Applicant: BASE SE
    Inventors: Jianqiang Qu, Neil Gregory Pschirer
  • Publication number: 20110027800
    Abstract: The present invention describes novel dyes, including coumarins, rhodamines, and rhodols that incorporate additional fused aromatic rings. The dyes of the invention absorb at a longer wavelength than structurally similar dyes that do not possess the fused aromatic rings. Many of the dyes of the invention are useful fluorescent dyes. The invention includes chemically reactive dyes, dye-conjugates, and the use of such dyes in staining samples and detecting ligands or other analytes.
    Type: Application
    Filed: October 11, 2010
    Publication date: February 3, 2011
    Applicant: LIFE TECHNOLOGIES CORPORATION
    Inventors: Zhenjun DIWU, Jixiang Liu, Kyle Gee
  • Patent number: 7816519
    Abstract: The present invention describes novel dyes, including coumarins, rhodamines, and rhodols that incorporate additional fused aromatic rings. The dyes of the invention absorb at a longer wavelength than structurally similar dyes that do not possess the fused aromatic rings. Many of the dyes of the invention are useful fluorescent dyes. The invention includes chemically reactive dyes, dye-conjugates, and the use of such dyes in staining samples and detecting ligands or other analytes.
    Type: Grant
    Filed: November 16, 2006
    Date of Patent: October 19, 2010
    Assignee: Life Technologies Corporation
    Inventors: Zhenjun Diwu, Jixiang Liu, Kyle Gee
  • Patent number: 7723521
    Abstract: A novel semiconductor device comprises an azaperylene organic semiconductor of the formula I wherein the substitutents are defined herein.
    Type: Grant
    Filed: May 3, 2006
    Date of Patent: May 25, 2010
    Assignee: Ciba Specialty Chemicals Corporation
    Inventors: Frank Bienewald, Beat Schmidhalter, Ulrich Berens, Hans Jürg Kirner
  • Publication number: 20100108959
    Abstract: The invention provides materials and methods for making anisotropic solids which may be in the form of films, layers, shaped elements, and other shaped articles. The methods provide anisotropic solids without the need for rolling, rubbing, or stretching to impart orientational alignment of the molecules of the solid. The methods employ organic or organometallic compounds which are soluble orienting molecules. The solvent or solvent system must be sufficiently volatile to be removed without disruption of the molecular orientation. The soluble orienting molecules include those containing one or more hydrophilic and/or ionic groups and the solvent or solvent system can be a polar organic solvent or solvent system or an aqueous solvent or solvent system. The invention also provides novel compounds having quaterrylene, perylene and naphthalene ring systems carrying one or more hydrophilic and/or ionic groups.
    Type: Application
    Filed: September 25, 2009
    Publication date: May 6, 2010
    Inventors: Travis D. Carson, Sean M. Casey, Isaac K. Iverson, Wonewoo Seo, Suk-Wah Tam-Chang
  • Publication number: 20090281279
    Abstract: Disclosed are analogues of trimethine cyanine dyes, which are useful for importing fluorescent properties to target materials by covalent and non-covalent association.
    Type: Application
    Filed: May 15, 2007
    Publication date: November 12, 2009
    Applicant: Carnegie Mellon University
    Inventors: Alan S. Waggoner, Ratnakar B. Mujumdar
  • Patent number: 7544448
    Abstract: A method for laser marking a substrate which method comprises exposing a composition comprising a tetrabenzodiazadiketoperylene pigment to laser radiation to produce a fluorescent marking readily apparent under UV light is disclosed. Many of the tetrabenzodiazadiketoperylenes herein are novel. This method can yield fluorescent markings which are not readily apparent under ambient light. A method for producing non-fluorescent laser marked substrates containing tetrabenzodiazadiketoperylene dyes is also disclosed.
    Type: Grant
    Filed: October 30, 2006
    Date of Patent: June 9, 2009
    Assignee: Ciba Specialty Chemicals Corporation
    Inventors: Damien Thurber Cole, Joseph E. Sarver, Colin Dennis Campbell
  • Publication number: 20090101890
    Abstract: A novel semiconductor device comprises an azaperylene organic semiconductor of the formula I (I) wherein each of R1, R2, R3 and R4 independently is selected from H, unsubstituted or substituted alkyl, unsubstituted or substituted alkenyl, unsubstituted or substituted alkynyl, unsubstituted or substituted aryl, halogen, Si(RH)3, XR6; or one or more of R1 and R2, R2 and R3, R3 and R4, together with the carbon atoms they are bonding to, form a saturated or unsaturated, unsubstituted or substituted carbocyclic or heterocyclic ring; R5 is OR7, SR7, NR7R8, unsubstituted or substituted alkyl, unsubstituted or substituted alkenyl, unsubstituted or substituted alkynyl, or unsubstituted or substituted aryl; R6 is Si(R11)3, unsubstituted or substituted alkyl, unsubstituted or substituted alkenyl, unsubstituted or substituted alkynyl, unsubstituted or substituted aryl; R7 is H, unsubstituted or substituted alkyl, unsubstituted or substituted alkenyl, unsubstituted or substituted alkynyl, unsubstituted or substituted aryl
    Type: Application
    Filed: May 3, 2006
    Publication date: April 23, 2009
    Inventors: Frank Bienewald, Beat Schmidhalter, Ulrich Berens, Hans Jurg Kirner
  • Publication number: 20090044863
    Abstract: Briefly described, embodiments of this disclosure include coronene charge-transport materials, methods of forming coronene charge-transport materials, and methods of using the coronene charge-transport materials.
    Type: Application
    Filed: February 28, 2006
    Publication date: February 19, 2009
    Inventors: Seth Marder, Zesheng An, Jungsheng Yu, Bernard Kippelen
  • Patent number: 7408062
    Abstract: Disclosed are analogues of trimethine cyanine dyes, which are useful for importing fluorescent properties to target materials by covalent and non-covalent association.
    Type: Grant
    Filed: January 27, 2003
    Date of Patent: August 5, 2008
    Assignee: Carnegie Mellon University
    Inventors: Alan S. Waggoner, Ratnakar B. Mujumdar
  • Publication number: 20080122428
    Abstract: The present invention relates to a method of determining voltage changes, e.g. in cell membranes, by means of a voltage-sensitive dye.
    Type: Application
    Filed: June 25, 2004
    Publication date: May 29, 2008
    Applicant: Max-Planck-Gesellschaft zur Forderungder Wissenschaften e. V.
    Inventors: Bernd Kuhn, Winfried Denk, Gerd Hubener, Peter Fromherz
  • Patent number: 7169922
    Abstract: The present invention describes novel dyes, including coumarins, rhodamines, and rhodols that incorporate additional fused aromatic rings. The dyes of the invention absorb at a longer wavelength than structurally similar dyes that do not possess the fused aromatic rings. Many of the dyes of the invention are useful fluorescent dyes. The invention includes chemically reactive dyes, dye-conjugates, and the use of such dyes in staining samples and detecting ligands or other analytes.
    Type: Grant
    Filed: November 13, 2003
    Date of Patent: January 30, 2007
    Assignee: Invitrogen Corporation
    Inventors: Zhenjun Diwu, Jixiang Liu, Kyle Gee
  • Patent number: 7135493
    Abstract: A compound having the following formula (I): wherein R1 is N-containing heterocyclic ring optionally substituted with one or more suitable substituent(s), R2 is hydroxyamino, R3 is hydrogen or a suitable substituent, L1 is —(CH2)n— (wherein n is an integer of 0 to 6) optionally substituted with one or more suitable substituent(s), wherein one or more methylene(s) may be replaced with suitable heteroatom(s), and L2 is lower alkenylene, or a salt thereof. The compound is useful as a histone deacetylase inhibitor.
    Type: Grant
    Filed: January 12, 2004
    Date of Patent: November 14, 2006
    Assignee: Astellas Pharma Inc.
    Inventors: Yasuharu Urano, Shigeki Satoh, Naoki Ishibashi, Kazunori Kamijo
  • Patent number: 6890377
    Abstract: Rylene dyes of the general formula I where R is hydrogen; unsubstituted or substituted C1-C30-alkyl, aryl or hetaryl; R? is unsubstituted or substituted C2-C30-alkyl or C5-C8-cycloalkyl, or substituted methyl; n is 0 or 1, their preparation and use for coloring high-molecular-weight organic and inorganic materials, and aminorylene-3,4-dicarboximide of the formula IV as their intermediates.
    Type: Grant
    Filed: February 14, 2002
    Date of Patent: May 10, 2005
    Assignees: BASF Aktiengesellschaft, Max-Planck-Gesellschaft zur Foerderung der Wissenschaften e.V.
    Inventors: Arno Böhm, Matthias Krieger, Stefan Becker, Klaus Müllen
  • Patent number: 6878825
    Abstract: Rylene derivatives of the general formula I where the variables have the following meanings: R is hydrogen or substituted or unsubstituted C1-C30-alkyl, aryl or hetaryl; R1 is hydrogen or bromine; R2 is hydrogen or C1-C6-alkyl; R3 is hydrogen, C1-C18-alkyl or substituted or unsubstituted aryl or hetaryl; and n is 2 or 3.
    Type: Grant
    Filed: February 14, 2002
    Date of Patent: April 12, 2005
    Assignees: BASF Aktiengesellschaft, Max-Planck-Gesellschaft zur Foerderung der Wissenschaften e.V.
    Inventors: Matthias Krieger, Arno Böhm, Erik Reuther, Klaus Müllen
  • Patent number: 6770654
    Abstract: This invention relates to: an indole derivative or a pharmaceutically acceptable salt thereof represented by formula (I): wherein R1 is, for example, hydrogen or C1-5 alkyl; R2 is, for example, hydrogen or hydroxy; R3 is, for example, hydrogen or hydroxy; —Z— is a crosslinkage having 2 to 5 carbon atoms; m is an integer from 0 to 3; n is an integer from 0 to 10; R4 and R5 are, for example, fluoro or hydroxy; R9 is, for example, hydrogen or C1-5 alkyl; and R10 and R11 are bound to each other to form, for example, —O—; and a pharmaceutical composition comprising the same, particularly a drug acting on &dgr; opioid receptor.
    Type: Grant
    Filed: May 19, 2003
    Date of Patent: August 3, 2004
    Assignee: Toray Industries, Inc.
    Inventors: Satoshi Sakami, Koji Kawai, Masayuki Maeda, Takumi Aoki, Shinya Ueno
  • Publication number: 20040068114
    Abstract: The invention relates to rylene derivatives of the general formula (I), in which: R represents hydrogen or optionally substituted C1-C30 alkyl, aryl or heteroaryl; R1 represents hydrogen or bromine; R2 represents hydrogen or C1-C6 alkyl; R3 represents hydrogen, C1-C18 alkyl or optionally substituted aryl or heteroaryl; and n represents 2 or 3.
    Type: Application
    Filed: August 20, 2003
    Publication date: April 8, 2004
    Inventors: Matthias Krieger, Arno Bohm, Erik Reuther, Klaus Mullen
  • Patent number: 6716979
    Abstract: The present invention describes novel dyes, including coumarins, rhodamines, and rhodols that incorporate additional fused aromatic rings. The dyes of the invention absorb at a longer wavelength than structurally similar dyes that do not possess the fused aromatic rings. Many of the dyes of the invention are useful fluorescent dyes. The invention includes chemically reactive dyes, dye-conjugates, and the use of such dyes in staining samples and detecting ligands or other analytes.
    Type: Grant
    Filed: August 4, 2001
    Date of Patent: April 6, 2004
    Assignee: Molecular Probes, Inc.
    Inventors: Zhenjun Diwu, Jiaxing Liu, Richard P. Haugland, Kyle R. Gee
  • Patent number: 6525200
    Abstract: Multicyclic aromatic compounds useful as complexing agents having the general formula: Methods of complexing and quantitating a component in a sample such as urea or guanidine are also disclosed.
    Type: Grant
    Filed: August 10, 2000
    Date of Patent: February 25, 2003
    Assignee: Roche Diagnostics Corporation
    Inventors: Alisher B. Khasanov, Thomas W. Bell
  • Patent number: 6517630
    Abstract: The present invention is directed to a pigment of the formula which, in a gravure ink, has a lightness L* of not more than 48, a chroma C* of at least 53 and a hue angle h of from 295 to 315.
    Type: Grant
    Filed: July 7, 2000
    Date of Patent: February 11, 2003
    Assignee: Ciba Specialty Chemicals Corporation
    Inventors: Yves Grandidier, Urs Schlatter
  • Patent number: 6491749
    Abstract: The present inventions relates to nucleus-extended perylenebisimides of formula (I) intermediates in the preparation of compounds (I) and processes for the preparation of those intermediates and also processes for the preparation of compounds, (I), and the use thereof as colorants.
    Type: Grant
    Filed: March 20, 2001
    Date of Patent: December 10, 2002
    Assignee: Ciba Specialty Chemicals Corporation
    Inventors: Heinz Langhals, Susanne Kirner, Patrick Blanke, Markus Speckbacher
  • Patent number: 6248884
    Abstract: Extended rhodamine compounds exhibiting favorable fluorescence characteristics having the structure are disclosed. In addition, novel intermediates for synthesis of these dyes are disclosed, such intermediates having the structure In addition, methods of making and using the dyes as fluorescent labels are disclosed.
    Type: Grant
    Filed: June 3, 1999
    Date of Patent: June 19, 2001
    Assignee: The Perkin-Elmer Corporation
    Inventors: Joe Y. L. Lam, Scott C. Benson, Steven M. Menchen
  • Patent number: 6162915
    Abstract: Chlorosulfonyl substituted aromatic heterocyclic compounds, such as 2-chlorosulfonyl[1,2,4]triazolo[1,5-c]pyrimidine compounds, were prepared in good yield by chloroxidation of di(aromatic heterocyclyl) disulfide compounds in a medium containing water, a water-immiscible organic solvent, and a phase transfer catalyst, such at tetrabutylammonium chloride.
    Type: Grant
    Filed: June 25, 1998
    Date of Patent: December 19, 2000
    Assignee: Dow AgroSciences LLC
    Inventors: Douglas L. Pearson, Jimmy J. Tai, Timothy J. Adaway
  • Patent number: 6156762
    Abstract: The present invention provides an indolomorphinan derivative or a pharmacologically acceptable acid addition salt thereof, and an agent for curing and preventing cerebral disorders composed of the derivative and salt thereof, which is represented by the following formula (I): ##STR1## [wherein R.sup.1 represents cyclopropylmethyl or the like; R.sup.2 and R.sup.3 each represent hydroxy methoxy, or the like; R.sup.4 represents hydrogen, methyl, benzyl, 3-isothiocyanatopropyl, or the like; and (R.sup.5).sub.m represents hydrogen, substituted benzo, or the like]. The compounds of the present invention have the excellent effect of preventing damage of the cerebral nerve cells.
    Type: Grant
    Filed: September 24, 1998
    Date of Patent: December 5, 2000
    Assignee: Toray Industries, Inc.
    Inventors: Hiroshi Nagase, Yoshifumi Imamura, Junichi Hirokawa, Susumu Matsuda, Yasushi Miyauchi
  • Patent number: 5849731
    Abstract: The present invention relates to indole derivatives represented by the following compound 1 and the pharmacologically acceptable acid addition salt thereof. ##STR1## The compounds of the present invention were found to exhibit strong antitussive and analgesic actions as a result of pharmacological evaluation, and can be used in the pharmaceutical field as effective antitussives and analgesics.
    Type: Grant
    Filed: May 16, 1997
    Date of Patent: December 15, 1998
    Assignee: Toray Industries, Inc.
    Inventors: Hiroshi Nagase, Koji Kawai, Takashi Endo, Shinya Ueno, Masayuki Maeda, Satoshi Sakami
  • Patent number: 5623080
    Abstract: A compound of the formula (I) or (II): ##STR1## where R.sup.1, R.sup.2, R.sup.5 and R.sup.6 are the same or different and represent a hydrogen atom or a halogen atom and R.sup.1 and R.sup.2 may combine to form a ring; R.sup.3, and R.sup.4 are the same or different and represent a hydrogen atom, a halogen atom, a benzoyl group, a group of the formula --L(CH.sub.2).sub.n R.sup.8 where n is 1 to 8, R.sup.8 is a hydrogen, hydroxy, amino, dialkylamino, --COR.sup.16 or --COOR.sup.14 where R.sup.16 is a hydrogen, chlorine, COCl, C.sub.1 -C.sub.8 alkyl, --NR.sub.2 or aryl and R.sup.14 is a hydrogen, C.sub.1 -C.sub.8 alkyl, aryl, COR, 2,4-dinitrophenyl, N-imido or --NR.sub.2 and L is a direct bond or C.dbd.O; W is .dbd.O; W.sup.1 is hydrogen or --OR.sup.9, where R.sup.9 is hydrogen, C.sub.1 -C.sub.8 alkyl, acyl or a group of the formula --(CH.sub.2).sub.n R.sup.10 where n is 1 to 8 and R.sup.10 is amino, dialkylamino, hydroxy, acryloyl or methacryloyl; Y is oxygen, sulfur, selenium, tellurium, C.dbd.O, or >N--R.
    Type: Grant
    Filed: February 15, 1995
    Date of Patent: April 22, 1997
    Assignee: Spectra Group Limited, Inc.
    Inventors: Douglas C. Neckers, Jianmin Shi