Process Of Forming The Unsaturated Hydrocarbyl Side Chain Patents (Class 546/352)
  • Patent number: 8933237
    Abstract: Methods for synthesizing deuterated vinylpyridine compounds of the Formula (1), wherein the method includes: (i) deuterating an acyl pyridine of the Formula (2) in the presence of a metal catalyst and D2O, wherein the metal catalyst is active for hydrogen exchange in water, to produce a deuterated acyl compound of Formula (3); (ii) reducing the compound of Formula (3) with a deuterated reducing agent to convert the acyl group to an alcohol group, and (iii) dehydrating the compound produced in step (ii) with a dehydrating agent to afford the vinylpyridine compound of Formula (1). The resulting deuterated vinylpyridine compounds are also described.
    Type: Grant
    Filed: January 16, 2014
    Date of Patent: January 13, 2015
    Assignee: UT-Battelle, LLC
    Inventors: Kunlun Hong, Jun Yang, Peter V. Bonnesen
  • Publication number: 20140213793
    Abstract: Methods for synthesizing deuterated vinylpyridine compounds of the Formula (1), wherein the method includes: (i) deuterating an acyl pyridine of the Formula (2) in the presence of a metal catalyst and D2O, wherein the metal catalyst is active for hydrogen exchange in water, to produce a deuterated acyl compound of Formula (3); (ii) reducing the compound of Formula (3) with a deuterated reducing agent to convert the acyl group to an alcohol group, and (iii) dehydrating the compound produced in step (ii) with a dehydrating agent to afford the vinylpyridine compound of Formula (1). The resulting deuterated vinylpyridine compounds are also described.
    Type: Application
    Filed: January 16, 2014
    Publication date: July 31, 2014
    Applicant: UT-Battelle, LLC
    Inventors: Kunlun Hong, Jun Yang, Peter V. Bonnesen
  • Publication number: 20140024836
    Abstract: Methods for synthesizing deuterated vinylpyridine compounds of the Formula (1), wherein the method includes: (i) deuterating an acyl pyridine of the Formula (2) in the presence of a metal catalyst and D2O, wherein the metal catalyst is active for hydrogen exchange in water, to produce a deuterated acyl compound of Formula (3); (ii) reducing the compound of Formula (3) with a deuterated reducing agent to convert the acyl group to an alcohol group, and (iii) dehydrating the compound produced in step (ii) with a dehydrating agent to afford the vinylpyridine compound of Formula (1). The resulting deuterated vinylpyridine compounds are also described.
    Type: Application
    Filed: July 19, 2012
    Publication date: January 23, 2014
    Applicant: UT-BATTELLE, LLC
    Inventors: Kunlun Hong, Jun Yang, Peter V. Bonnesen
  • Publication number: 20130281700
    Abstract: The invention relates to palladium(0)-tris{tri-[3,5-bis(trifluoromethyl)-phenyl]-phosphine} complex of formula (I), as well as to its preparation and use. This compound is outstandingly stable, and can be used as catalyst with excellent results.
    Type: Application
    Filed: June 14, 2013
    Publication date: October 24, 2013
    Applicants: CHINOIN GYOGYSZER-ES VEGYESZETI TER-MEKEK GYARA ZRT, H4SEP KFT
    Inventors: Zoltán DALICZEK, Tibor SOÓS, Zoltán FINTA, Géza Timári, Gábor Vlád
  • Patent number: 8420812
    Abstract: A process for the palladium-catalyzed coupling of terminal alkynes with heteroaryl tosylates and heteroaryl benzenesulfonates The present invention relates to a process for the regioselective synthesis of compounds of the formula (I), wherein D, J and W have the meanings indicated in the claims. The present invention provides an efficient and general palladium-catalyzed coupling process of heteroaryl tosylates with terminal alkynes to a wide variety of substituted, multifunctional heteroaryl-1-alkynes of the formula I.
    Type: Grant
    Filed: December 23, 2009
    Date of Patent: April 16, 2013
    Assignee: Sanofi
    Inventors: Omar Rkyek, Marc Nazare, Andreas Lindenschmidt, Jorge Alonso, Matthias Urmann, Nis Halland
  • Publication number: 20120245348
    Abstract: Disclosed herein are phosphine compounds represented by the general formula (4): and corresponding phosphonium salts represented by the general formula (4a): Also disclosed are processes for the preparation of these phosphines and phosphonium salts as well as their use as ligands in catalytic reactions.
    Type: Application
    Filed: April 2, 2012
    Publication date: September 27, 2012
    Inventors: Herbert PLENIO, Christoph FLECKENSTEIN, Renat KADYROV, Juan ALMENA, Axel MONSEES, Thomas RIERMEIER
  • Publication number: 20110172432
    Abstract: The invention relates to the field of chemistry, especially organic chemistry, and more specifically the field of heterogeneous palladium catalysts used to catalyse chemical reactions involving the formation of carbon-carbon bonds. The invention also relates to a method for synthesising a heterogeneous palladium catalyst that can catalyse a C—C coupling reaction, the method essentially including steps of providing a solid substrate onto which groups of formula —PR1R2, wherein R1 is an optionally substituted alkyl group, or an optionally substituted cycloalkyl group, et R2 is an optionally substituted aryl group or an optionally substituted heteroaryl group, have been covalently bonded, and incorporating a catalytically effective amount of palladium into the resulting substituted substrate. The invention further relates to the resulting catalysts and to the uses thereof in C—C coupling reactions.
    Type: Application
    Filed: April 11, 2008
    Publication date: July 14, 2011
    Applicants: UNIVERSITE DE HAUTE ALSACE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Claude Le Drian, Jean-Michel Becht, Stéphane Schweizer
  • Patent number: 7105707
    Abstract: Mono- and disubstituted aryl or heterocyclic acetylenes are produced by a process comprising reacting an aryl nitrile with an alkynylzinc compound, a bis-alkynylzinc compound, or an alkynylmagnesium compound, in the presence of a nickel/phosphine catalyst.
    Type: Grant
    Filed: December 17, 2003
    Date of Patent: September 12, 2006
    Assignee: PharmaCore, Inc.
    Inventors: Joseph A. Miller, Jonathan M. Penney
  • Patent number: 6897320
    Abstract: The present invention relates to a process for the preparation of 2,6-divinylpyridine and 2-methyl-6-vinylpyridine over modified zeolite catalysts. In particular, it relates to the method for the synthesis of 2,6-divinylpyridine and 2-methyl-6-vinylpyridine from 2,6-lutidine and formaldehyde in vapour phase in an eco-friendly method with high yield and selectivity. This invention provides a non-corrosive, eco-friendly process, where the catalyst can be reused for many times. 2,6-Divinylpyridine is useful stating material in polymer industry.
    Type: Grant
    Filed: March 25, 2003
    Date of Patent: May 24, 2005
    Assignee: Council of Scientific and Industrial Research
    Inventors: Shivanand Janardan Kulkarni, Madhavi Gangapuram, Vijaya Raghavan Kondapuram
  • Publication number: 20040192925
    Abstract: The present invention relates to a process for the preparation of 2,6-divinylpyridine and 2-methyl-6-vinylpyridine over modified zeolite catalysts. In particular, it relates to the method for the synthesis of 2,6-divinylpyridine and 2-methyl-6-vinylpyridine from 2,6-lutidine and formaldehyde in vapour phase in an eco-friendly method with high yield and selectivity. This invention provides a non-corrosive, eco-friendly process, where the catalyst can be reused for many times.
    Type: Application
    Filed: March 25, 2003
    Publication date: September 30, 2004
    Inventors: Shivanand Janardan Kulkarni, Madhavi Gangapuram, Vijaya Raghavan Kondapuram
  • Patent number: 6753447
    Abstract: This invention discloses a process for synthesizing an amine functionalized monomer that comprises (1) reacting a secondary amine with a 2,3-dihalopropene to produce a vinyl halide containing secondary amine having a structural formula selected from the group consisting of wherein R and R′ can be the same or different and represent allyl, alkoxyl or alkyl groups containing from 1 to about 10 carbon atoms, and wherein X represents a halogen atom, and wherein m represents an integer from 4 to about 10, and wherein X represents a halogen atom; and (2) reacting the vinyl halide containing secondary amine with a vinyl magnesium halide to produce the monomer having a structural formula wherein R and R′ can be the same or different and represent alkyl, allyl or alkoxyl groups containing from 1 to about 10 carbon atoms, and wherein m represents an integer from about 4 to about 10.
    Type: Grant
    Filed: February 20, 2003
    Date of Patent: June 22, 2004
    Assignee: The Goodyear Tire & Rubber Company
    Inventors: Adel Farhan Halasa, Wen-Liang Hsu, Naoya Ogata
  • Patent number: 6727365
    Abstract: The present invention relates to an improved eco-friendly process for the preparation of vinylpyridine from corresponding picoline over modified zeolite catalyst in vapour phase which comprises reacting picoline with formaldehyde with a molar ratio of formaldehyde to picoline in the range of 1:1 to 4:1, at a temperature ranging between 200° C. to 450° C., at a weight hourly in the range of 0.25 hr−1-1.00 hr−1 over a modified commercial zeotlite catalyst to obtain a high yield and selectivity of the desired product.
    Type: Grant
    Filed: October 31, 2002
    Date of Patent: April 27, 2004
    Inventors: Shivanand Janardan Kulkarni, Gangapuram Madhavi, Venkataraman Viswanathan, Kondapuram Vi jaya Raghavan
  • Patent number: 6603013
    Abstract: The present invention relates to a process wherein heterogeneous finely-dispersed palladium catalysts are used in a cross-coupling reaction of alkenyl halides and aryl or heteroaryl boronic acids in the presence of base in an aprotic solvent to produce aryl- or heteroaryl-olefin compounds of Formula I:
    Type: Grant
    Filed: July 16, 2001
    Date of Patent: August 5, 2003
    Assignee: Merck & Co., Inc.
    Inventors: Yongkui Sun, Carl LeBlond, John R. Sowa, Jr.
  • Patent number: 6576803
    Abstract: The present invention provides a catalyst for the oxidative dehydrogenation of a lower hydrocarbon to form at least one higher hydrocarbon and/or lower olefin. In one embodiment, the catalyst includes a nonstoichiometric rare earth oxycarbonate of the formula MXCYOZ having a disordered and/or defect structure, wherein M is at least one rare earth element selected from the group consisting of La, Pr, Nd, Sm, Eu, Gd, Tb, Dy, Ho, Er, and Tm; X=2; Z=3+AY; A is less than about 1.8, and Y is the number of carbon atoms in the oxycarbonate. When used for the oxidative dehydrogenation of a lower hydrocarbon at a pressure above about 100 psig, the catalyst has a selectivity of at least about 40% to at least one higher hydrocarbon and/or lower olefin. Methods for preparing catalysts taught by the invention and processes for using the catalysts for the oxidative dehydrogenation of lower hydrocarbons are also provided.
    Type: Grant
    Filed: April 16, 2002
    Date of Patent: June 10, 2003
    Assignee: Union Carbide Chemicals & Plastics Technology Corporation
    Inventors: Rick David Cantrell, Anca Ghenciu, Kenneth Dwight Campbell, David Michael Anthony Minahan, Madan Mohan Bhasin, Alistair Duncan Westwood, Kenneth Andrew Nielsen
  • Publication number: 20030008889
    Abstract: The present invention provides novel aminoadamantane derivatives, methods of making the derivatives, compositions including the novel aminoadamantane derivatives, and methods for the treatment and prevention of neurological diseases using the derivatives and compositions.
    Type: Application
    Filed: July 19, 2002
    Publication date: January 9, 2003
    Inventors: Yuqiang Wang, Wenqing Ye, James W. Larrick, Jonathan S. Stamler, Stuart A. Lipton
  • Patent number: 6492524
    Abstract: The present invention provides an improved process for the synthesis of aryl pyridine bases by reacting an aromatic aldehyde or ketone and allylic alcohol or aldehyde in presence of ammonia in gas phase, in high yield and selectivity with catalyst obtained by optionally modifying a zeolite having an atomic ratio of Si to Al, 2.5 to 12.5 and /or with at least one metal ion and/or metal compound selected from the group consisting of lead and lanthanum. This process provides an eco-friendly, more economical and highly selective heterogeneous method.
    Type: Grant
    Filed: March 27, 2001
    Date of Patent: December 10, 2002
    Assignee: Council of Scientific and Industrial Research
    Inventors: Shivanand Janardan Kulkarni, Kondapuram Vijaya Raghavan, Srinivas Nagabandi, Radha Rani Vippagunta
  • Publication number: 20020123633
    Abstract: Described are preferred processes for preparing alkenyl-substituted nitrogenous heterocycles such as vinylpyridines, which comprise reacting a corresponding methyl-substituted heterocycle with a C1 compound such as formadehyde in the vapor phase over a zeolite catalyst having acidic and basic catalytic sites. The preferred zeolite is a medium-pore zeolite, for example having a constraint index of about 0.5 to about 12. Processes of the invention can be conducted as facile, one-step syntheses utilizing relatively low ratios of alkyl-substituted starting heterocycle (e.g. &agr;-picoline or &ggr;-picoline) to formaldehyde while nonetheless achieving high selectivities and yields of the corresponding alkenyl compound.
    Type: Application
    Filed: October 22, 2001
    Publication date: September 5, 2002
    Inventors: Colin H. McAteer, Aaron J. Edwards, Yarlagadda V. Subba Rao
  • Patent number: 6372693
    Abstract: The invention relates to 2-(3-alkenylbenzoyl)cyclohexane-1,3-diones of the formula I where the variables have the following meanings: R1, R2 are hydrogen, nitro, halogen, cyano, thiocyanato, alkyl, haloalkyl, alkoxyalkyl, alkenyl, alkynyl, —OR6, —OCOR7, —OSO2R7, —SH, —S(O)nR8, —SO2OR6, —SO2NR6R9, —NR9SO2R7 or —NR9COR7; R3 is hydrogen, halogen, alkyl, haloalkyl, alkoxy, alkenyl, alkynyl; R4, R5 are hydrogen, nitro, halogen, cyano, thiocyanato, alkyl, haloalkyl, cycloalkyl, alkenyl, cycloalkenyl, alkynyl, alkoxy, alkylthio, haloalkoxy, —COR10, —CO2R10, —COSR10, —CONR10R11, —C(R12)═NR13, —PO(OR10)(OR11); unsubstituted or substituted alkyl, heterocyclyl, heterocyclylalkyl, phenyl, phenylalkyl, hetaryl or hetarylalkyl; or R4 and R5 together form an alkanediyl chain which can be substituted and/or can be interrupted by a hetero atom; Q is an unsubstituted or substituted cyclohexane-1,3-dione ring wh
    Type: Grant
    Filed: November 2, 1999
    Date of Patent: April 16, 2002
    Assignee: BASF Aktiengesellschaft
    Inventors: Ernst Baumann, Wolfgang von Deyn, Stefan Engel, Regina Luise Hill, Uwe Kardorff, Guido Mayer, Martina Otten, Michael Rack, Joachim Rheinheimer, Matthias Witschel, Karl-Otto Westphalen, Ulf Misslitz, Helmut Walter
  • Patent number: 6197966
    Abstract: A method for producing an optically active amino alcohol compound of the formula [3], an enantiomer thereof or a salt thereof, comprising reacting a mesoepoxide compound of the formula [1] with a compound of the formula [2] in the presence of a mixed catalyst comprising a Lewis acid and a proton donor: wherein R1, R2 and R3 are each H, an optionally substituted lower alky, and the like, or R1 and R1 or R2 and R3 may form an optionally substituted ring; and R4 and R5 are each H, an optionally substituted lower alkyl, and the like, or R4 and R5 may form an optionally substituted ring together with the adjacent N, or an imide group or azide group together with the adjacent N, and R6 is H or a silyl group. The present invention enables stereoselective production of a desired intermediate compound, which is an HIV protease inhibitor, extremely efficiently as compared to conventional methods.
    Type: Grant
    Filed: January 15, 1999
    Date of Patent: March 6, 2001
    Assignees: Japan Tobacco Inc., Agouron Pharmaceuticals, Inc.
    Inventors: Takashi Inaba, Shoichi Sagawa, Hiroyuki Abe
  • Patent number: 6008364
    Abstract: There is provided a process for producing an alkenyl-substituted pyridine derivative using, a solid base catalyst which is obtained by heating a metal oxide selected from the group consisting of alumina, an alkaline earth metal oxide and a hydrotalcite withan alkali metal,an alkali compound and an alkali metal oran alkali compound and an alkali metal hydride under an inert gas atmosphere at a temperature within the range of 100-700.degree. C.
    Type: Grant
    Filed: July 10, 1998
    Date of Patent: December 28, 1999
    Assignee: Sumitomo Chemical Company, Limited
    Inventors: Michio Yamamoto, Gohfu Suzukamo
  • Patent number: 5861230
    Abstract: There is described a novel process of polymerizing 4-vinyl pyridine monomer in an aqueous polymerization system which comprises preparing an aqueous solution of polyvinyl alcohol, and contacting said aqueous solution of a polyvinyl alcohol with less than about 10% by weight of 4-vinyl pyridine monomer and a water-soluble initiator capable of decomposing to give free radicals.The resultant dispersion of the novel polymerization process comprises a homogeneous, i.e., weight average molecular weight and particle size, poly-4-vinylpyridine, with no appreciable residual 4-vinyl pyridine monomer.The resultant dispersion may be used to coat image- and ink-receiving layers of image-recording materials and ink jet recording sheets, respectively.
    Type: Grant
    Filed: April 21, 1997
    Date of Patent: January 19, 1999
    Assignee: Polaroid Corporation
    Inventors: Shawn P. Lambert, Xiaojia Z. Wang
  • Patent number: 5360911
    Abstract: A novel process is disclosed for producing stilbazolium salts. Said novel process employs a heterocyclic amine catalyst, such as pyrrolidine, an alkylated pyridine salt and a substituted benzaldehyde which unexpectedly results in increased reaction rates and product yields.
    Type: Grant
    Filed: June 17, 1993
    Date of Patent: November 1, 1994
    Assignee: General Electric Company
    Inventors: Eugene P. Boden, Peter D. Phelps, Kevin R. Stewart
  • Patent number: 5243099
    Abstract: Organic polymer additive containing polar functional groups enhances the stability of palladium-containing catalysts for the telomerization of conjugated diolefins in the presence of active hydrogen-containing telomerization agent to produce alpha-substituted alkadienes.
    Type: Grant
    Filed: September 9, 1992
    Date of Patent: September 7, 1993
    Assignee: Union Carbide Chemicals & Plastics Technology Corporation
    Inventor: Diane L. Packett
  • Patent number: 5169981
    Abstract: Organic polymer additive containing polar functional groups enhances the stability of palladium-containing catalysts for the telomerization of conjugated diolefins in the presence of active hydrogen-containing telomerization agent to produce alpha-substituted alkadienes.
    Type: Grant
    Filed: December 6, 1991
    Date of Patent: December 8, 1992
    Assignee: Union Carbide Chemicals & Plastics Technology Corporation
    Inventor: Diane L. Packett
  • Patent number: 5001294
    Abstract: Aromatic alkenes, especially diarylbutadienes are produced in a simple economic process by reaction of an anil with an organic compound having a non-aromatic unsaturated system conjugated with an aromatic system, and a terminal methyl group pendent from the non-aromatic unsaturated system; in particular the organic compound is a propenyl-substituted aromatic compound.
    Type: Grant
    Filed: October 31, 1988
    Date of Patent: March 19, 1991
    Inventor: Allan S. Hay
  • Patent number: 4876349
    Abstract: The compounds of the formula ##STR1## wherein X and Y are independently --CH.sub.2 -- or >C(CH.sub.3).sub.2 ; Z is --CHR.sup.8 --, >Co, >CR.sup.8 OR.sup.7 , --CHR.sup.8 --CHR.sup.8 --, --CHOR.sup.7 --CH.sub.2 --, --CO--CHOR.sup.7 or --CHOR.sup.7 --CHOR.sup.7 --R.sup.1 is a 5- or 6-membered, monocyclic heterocyclic group which optionally can be C-substituted by halogen, lower-alkyl, lower-alkoxy, acyloxy, nitro, hydroxy, amino, lower-alkylamino or di-lower-alkylamino and/or which can be substituted on a ring --NH-- group by lower-alkyl; R.sup.2 and R.sup.3 are independently hydrogen, lower-alkyl, trifluoromethyl or halogen and one of R.sup.2 and R.sup.3 always is trifluoromethyl or lower-alkyl; R.sup.4 and R.sup.5 are independently hydrogen, alkyl, alkoxy or halogen; R.sup.6 is hydrogen, lower-alkyl or --OR.sup.7 ; R.sup.7 is hydrogen, lower-alkyl or acyl; R.sup.8 is hydrogen or lower-alkyl; and R.sup.7 and R.sup.8 can be the same or different from one another.
    Type: Grant
    Filed: July 10, 1987
    Date of Patent: October 24, 1989
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Michael Klaus, Ekkehard Weiss
  • Patent number: 4755600
    Abstract: Thermosettable prepolymers or resins are prepared by reacting (1) a pyrazine compound containing at least two substituent groups which have a hydrogen atom attached to a carbon atom which is attached to the ring such as tetramethylpyrazine, (2) a material containing at least two aromatic aldehyde groups, and (3) at least one of (a) a nitrogen containing aromatic heterocyclic compound containing at least one hydrogen atom attached to a carbon atom attached to the ring and a polymerizable unsaturated group such as 2-methyl-5-vinylpyridine or (b) an aldehyde containing at least one polymerizable unsaturated group such as 4-isopropenyl-1-cyclohexene-1-carboxaldehyde. These prepolymers or resins are curable to thermoset products having good mechanical and thermal properties by heat and pressure or by homopolymerization or copolymerization with N,N'-bis-imides such as 1,1'-(methylenedi-4,1-phenylene)bismaleimide. The prepolymers are suitable for preparing composites.
    Type: Grant
    Filed: March 17, 1986
    Date of Patent: July 5, 1988
    Assignee: The Dow Chemical Company
    Inventor: Duane S. Treybig
  • Patent number: 4703124
    Abstract: A process for introduction of styrenes in the side chain of substituted aromatic compounds, said side chain containing at least one hydrogen atom in the .alpha.-position thereof, is disclosed, comprising reacting the styrenes and the substituted aromatic compounds in the presence of (A) an alkali metal and (B) a compound containing a benzyloxy group or alkyl and/or aryl-substituted benzyloxy group. Use of (A) and (B) as a reaction accelerator permits to introduce the styrenes in the side chain of the substituted aromatic compounds in high yield and selectivity.
    Type: Grant
    Filed: December 19, 1985
    Date of Patent: October 27, 1987
    Assignee: Idemitsu Kosan Company Limited
    Inventors: Toshiyuki Tsubouchi, Tomiyasu Minokami, Nobuaki Shimizu
  • Patent number: 4620055
    Abstract: The present invention provides a novel process for the preparation of styrene, stilbene, and/or substituted derivatives thereof. The process involves the reaction of an aryl sulfonyl chloride with an olefinic compound in the presence of a catalytic amount of a metal catalyst consisting essentially of palladium.
    Type: Grant
    Filed: October 7, 1985
    Date of Patent: October 28, 1986
    Assignee: Eastman Kodak Company
    Inventors: Carl M. Lentz, James R. Overton, David D. Cornell
  • Patent number: 4477673
    Abstract: The invention relates to compounds of the formula I ##STR1## wherein R' is bound in the 4- or 5-position, R and R' are --CH.sub.2 OH, --CH.sub.2 CH.sub.2 OH, --CH.sub.2 CH.sub.2 OCH.sub.2 C.sub.6 H.sub.5, --CH.sub.2 --X, --CH.sub.2 P.sup..sym. (Y).sub.3 X.sup..crclbar., --CH.sub.2 P(O)(C.sub.1-3 alkoxy).sub.2 or --CH.dbd.CH.sub.2, R" is C.sub.1-10 alkyl, X is a halogen atom, X.sup..crclbar. is the anion corresponding to X and Y is phenyl or phenyl which is substituted by a C.sub.1 -C.sub.5 alkyl group. These compounds can be obtained by a novel simple process in good to very good yield by co-cyclotrimerizing nitriles R"--CN with alkynes HC.dbd.C--Z (Z is --CH.sub.2 OH, --CH.sub.2 CH.sub.2 OH or --CH.sub.2 CH.sub.2 OCH.sub.2 C.sub.6 H.sub.5), in the presence of a cobalt(I) catalyst, dehydrating the resultant pyridines either to compounds of the formula I, in which R and R" are --CH.dbd.CH.sub.
    Type: Grant
    Filed: January 17, 1983
    Date of Patent: October 16, 1984
    Assignee: Ciba-Geigy Corporation
    Inventor: Jurgen Kaschig
  • Patent number: 4374051
    Abstract: Certain pyridine derivatives have been found to possess particularly useful odorous properties. They develop green and herbaceous fragrance notes and have a specific utility for the reconstitution of the essential oil of Artemesia Vulgaris.
    Type: Grant
    Filed: January 26, 1981
    Date of Patent: February 15, 1983
    Assignee: Firmenich SA
    Inventors: Regula Naf, Wilhelm Pickenhagen, Anthony F. Morris
  • Patent number: 4266061
    Abstract: A process is described for the catalytic, selective preparation of 2-vinylpyridine from acetylene and acrylonitrile using a cyclopentadienylcobalt catalyst or .pi.-allylcobalt catalyst at elevated temperature in an inert solvent, wherein the acrylonitrile concentration is up to 2 mols/liter and the reaction is carried out at a temperature over 140.degree. C. and up to 180.degree. C., the reaction time being not more than 50 minutes.
    Type: Grant
    Filed: September 14, 1979
    Date of Patent: May 5, 1981
    Assignee: Studiengesellschaft Kohle mbH
    Inventors: Helmut Bonnemann, Marc Samson
  • Patent number: 4246421
    Abstract: This invention relates to an improved process for the dehydrogenation of alkyl-substituted aromatic compounds to the corresponding alkenyl-substituted aromatics in the presence of oxygen and in the presence of an improved metal phosphate catalyst composition.
    Type: Grant
    Filed: September 15, 1978
    Date of Patent: January 20, 1981
    Assignee: The Standard Oil Company
    Inventors: Joseph P. Bartek, Robert K. Grasselli