Unsubstituted Or Hydrocarbyl Substituted Only, Or Salt Thereof Patents (Class 546/348)
  • Patent number: 9925495
    Abstract: An electrolyte-separating membrane includes a carrier made of a porous and permeable synthetic thermoplastic material that is larger than 0.8 mm in thickness and an active layer made of a material able to induce insertion and deinsertion reactions for selective transfer of cations through the membrane. The active layer is deposited on the carrier and is hermetic. The material of the active layer may in particular be a molybdenum cluster chalcogenide. The invention aims to provide an electrolyte-separating membrane that is able to transfer cations selectively and that may be manufactured with large dimensions. The invention also relates to a cation transfer method employing this membrane and to a process for manufacturing said membrane, in particular by selective laser sintering of a powdered polymer.
    Type: Grant
    Filed: February 5, 2014
    Date of Patent: March 27, 2018
    Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE DE LORRAINE
    Inventors: Jean-Marie Lecuire, Samuel Philippe Claude Kenzari, Elodie Guyot, Sébastien Diliberto
  • Publication number: 20150119577
    Abstract: A membrane separation process using a highly fluorinated polymer membrane that selectively permeates water of an aqueous ionic liquid solution to provide dry ionic liquid. Preferably the polymer is a polymer that includes polymerized perfluoro-2,2-dimethyl-1,3-dioxole (PDD). The process is also capable of removing small molecular compounds such as organic solvents that can be present in the solution. This membrane separation process is suitable for drying the aqueous ionic liquid byproduct from precipitating solutions of biomass dissolved in ionic liquid, and is thus instrumental to providing usable lignocellulosic products for energy consumption and other industrial uses in an environmentally benign manner.
    Type: Application
    Filed: October 29, 2014
    Publication date: April 30, 2015
    Applicant: CMS TECHNOLOGIES HOLDINGS, INC.
    Inventors: Daniel Campos, Andrew Edward Feiring, Sudipto Majumdar, Stuart Nemser
  • Publication number: 20150094233
    Abstract: The present invention provides a compound represented by the formula (I): or a salt thereof; and a method of quantitatively analyzing an amino group-containing target substance, including labeling a target substance in samples by using, as a labeling compound, two or more of such compounds having a mutually different mass due to isotope labeling, to confer a mass difference to the target substance between two or more samples, and the like.
    Type: Application
    Filed: March 28, 2013
    Publication date: April 2, 2015
    Inventors: Shigeru Matsukawa, Kazumi Narita, Yasushi Arakawa, Haruki Shimodaira
  • Patent number: 8889686
    Abstract: L malate salts of (6-(5-chloro-2-pyridyl)-5-[(4-methyl-1-piperazinyl)carbonyloxy]-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazine) are disclosed for decreasing the bitterness of eszopiclone dosage forms
    Type: Grant
    Filed: July 1, 2013
    Date of Patent: November 18, 2014
    Assignee: Sunovion Pharmaceuticals Inc.
    Inventors: H. Scott Wilkinson, Richard Hsia, Tushar Misra, Kostas Saranteas, Patrick Mousaw
  • Publication number: 20140286852
    Abstract: A method for producing carbon nanotubes having specific lengths, said method comprising: producing carbon nanotubes having at least two types of zones along their lengths, wherein each zone type has a characteristic structure that confers specific properties; and processing said carbon nanotubes to selectively attack one zone type more aggressively than another zone type.
    Type: Application
    Filed: March 19, 2014
    Publication date: September 25, 2014
    Inventors: Nolan Nicholas, David Carnahan
  • Patent number: 8802687
    Abstract: Cadherin-11 inhibitors, including 4-(2-phenylpyridin-3-yl)phenol, and methods for the prevention and treatment of cadherin-11 related diseases are described herein. Cadherin-11 related diseases include cancer and rheumatoid arthritis.
    Type: Grant
    Filed: February 9, 2010
    Date of Patent: August 12, 2014
    Assignee: Georgetown University
    Inventors: Stephen W. Byers, Sivanesan Dakshanamurthy, Jaime M. Guidry Auvil, Milton L. Brown
  • Publication number: 20140160384
    Abstract: The present invention relates to a smectic A phase liquid crystal material, which contains at least one heterocyclic compound. The smectic A phase liquid crystal material of the present invention may further contain at least one ester compound and an ionic compound. By using the smectic A phase liquid crystal material in a display device, a displayed image can be completely erased without any residual images after a long-term placement or a long-term drive, the contrast is generally higher than 10, and the drive voltage is generally 20 to 50 V.
    Type: Application
    Filed: September 27, 2012
    Publication date: June 12, 2014
    Inventors: Wenlei Li, Gang Sun, Huan Yin, Zhixian Tan, Huaibin Zhai
  • Publication number: 20140163163
    Abstract: The present disclosure relates to a polymerization initiator and a modified conjugated diene polymer prepared using the same, and more particularly to a polymerization initiator which is a compound represented by the following formula 1, and a modified conjugated diene polymer prepared using the same: wherein R1 to R5 are each independently hydrogen or a C1-10 alkylgroup or its carbanion; n? represents the number of negative charges of the carbanion and is 1? to 5?; M is a metal; and n is equal to the number of carbanions in R1 to R5.
    Type: Application
    Filed: December 4, 2013
    Publication date: June 12, 2014
    Applicant: LG CHEM, LTD.
    Inventors: Ro Mi LEE, Du Weon YOON, Chang Woo KIM, Jun Hyun PARK, Sang Mi LEE
  • Patent number: 8742128
    Abstract: Provided is a process for producing a high-purity pyridine compound from a crude pyridine compound that contains a diazine compound as an impurity, the method including a reaction step of reacting the crude pyridine compound with an aluminum hydride compound, and a distillation step of distilling the product obtained from the reaction step. The aluminum hydride compound preferably contains one or more compounds selected from lithium aluminum hydride and sodium aluminum hydride.
    Type: Grant
    Filed: May 22, 2009
    Date of Patent: June 3, 2014
    Assignee: Air Water Inc.
    Inventors: Koichi Fukui, Takeshi Namekata, Ikuo Ito
  • Patent number: 8680159
    Abstract: Substituted benzamide compounds corresponding to formula (I) in which R5, R6, R7, R8, a, b, c, d, t, D and X have defined meanings, a process for their preparation, pharmaceutical compositions comprising such compounds, and a method of using such compounds to treat pain and other conditions mediated at least in part via the bradykinin 1 receptor.
    Type: Grant
    Filed: September 22, 2011
    Date of Patent: March 25, 2014
    Assignee: Gruenenthal GmbH
    Inventors: Melanie Reich, Stefan Schunk, Ruth Jostock, Jean De Vry, Christa Kneip, Tieno Germann, Michael Engels
  • Publication number: 20140058101
    Abstract: The invention is directed to a phosphine compound represented by general formula (1) wherein R? and R? independently are selected from alkyl, cycloalkyl and 2-furyl radicals, or R? and R? are joined together to form with the phosphorous atom a carbon-phosphorous monocycle comprising at least 3 carbon atoms or a carbon-phosphorous bicycle; the alkyl radicals, cycloalkyl radicals, and carbon-phosphorous monocycle being unsubstituted or substituted by at least one radical selected from the group of alkyl, cycloalkyl, aryl, alkoxy, and aryloxy radicals; Cps is a partially substituted or completely substituted cyclopentadien-1-yl group, including substitutions resulting in a fused ring system, and wherein a substitution at the 1-position of the cyclopentadien-1-yl group is mandatory when the cyclopentadien-1-yl group is not part of a fused ring system or is part of an indenyl group. Also claimed is the use of these phosphines as ligands in catalytic reactions and the preparation of these phosphines.
    Type: Application
    Filed: October 29, 2013
    Publication date: February 27, 2014
    Applicant: Evonik Degussa GmbH
    Inventors: Herbert Plenio, Christoph Fleckenstein, Renat Kadyrov, Juan Almena, Axel Monsees, Thomas Riermeier
  • Patent number: 8623942
    Abstract: The present invention provides a liquid curable epoxy resin composition that has excellent storage stability and curing properties and provides a cured product having excellent properties, particularly, excellent organic solvent resistance. For that purpose, a clathrate containing a carboxylic acid compound and at least one selected from the group consisting of an imidazole compound represented by formula (I), wherein R1 to R4 each represent a hydrogen atom or the like, and 1,8-diazabicyclo[5.4.0]undecene-7 (DBU) is mixed in an epoxy resin. The liquid curable epoxy resin composition uses a liquid epoxy resin or an organic solvent.
    Type: Grant
    Filed: March 9, 2010
    Date of Patent: January 7, 2014
    Assignee: Nippon Soda Co., Ltd.
    Inventors: Masami Kaneko, Kazuo Ono, Natsuki Amanokura, Naoyuki Kamegaya
  • Publication number: 20130303466
    Abstract: Provided herein are methods for treating conditions associated with a chemosensory receptor, including diabetes, obesity, and other metabolic diseases, disorders or conditions by administering a composition comprising a chemosensory receptor ligand. Also provided herein are chemosensory receptor ligand compositions and methods for the preparation thereof for use in the methods of the present invention.
    Type: Application
    Filed: October 18, 2011
    Publication date: November 14, 2013
    Applicant: ELCELYX THERAPEUTICS, INC.
    Inventors: Martin R. Brown, Christopher R.G. Jones, Nigel R.A. Beeley, Alain D. Baron
  • Patent number: 8501651
    Abstract: A catalyst system comprising a half-sandwich chromium complex, an activator support and an optional cocatalyst. A compound of formula Cp?Cr(Cl)2(Ln), where Cp? is ?5—C5H4CH2CH2CH?CH2 and Ln is pyridine, THF or diethylether. A compound of formula Cp?Cr(Cl)2(Ln), where Cp? is ?5—C5H4C(Me)2CH2CH2CH?CH2 and Ln is pyridine, THF or diethylether.
    Type: Grant
    Filed: September 24, 2010
    Date of Patent: August 6, 2013
    Assignee: Chevron Phillips Chemical Company LP
    Inventors: Errun Ding, Albert P. Masino, Joel L. Martin, Youlu Yu
  • Patent number: 8460851
    Abstract: A salt represented by the formula (I): wherein Q1 and Q2 each independently represent a fluorine atom or a C1-C6 perfluoroalkyl group, L1 represents *—CO—O-La- or *—CH2—O-Lb-, * represents a binding position to —C(Q1)(Q2)-, La and Lb independently represent a C1-C15 divalent saturated hydrocarbon group in which one or more —CH2— can be replaced by —O— or —CO—, ring W1 represents a C2-C36 nitrogen-containing heterocyclic group in which one or more —CH2— can be replaced by —O—, and Z1? represents an organic counter ion.
    Type: Grant
    Filed: January 6, 2011
    Date of Patent: June 11, 2013
    Assignee: Sumitomo Chemical Company, Limited
    Inventors: Satoshi Yamaguchi, Koji Ichikawa
  • Publication number: 20130126857
    Abstract: A novel organic compound suitably used for a green-light-emitting device and an organic light-emitting device are provided. An organic light-emitting device and an image display apparatus containing a naphtho[2?,3?:5,6]indeno[1,2,3-cd]pyrene derivative represented by general formula (1) as a dopant: wherein in general formula (1), R1 to R16 are each independently selected from a hydrogen atom, a halogen atom, substituted or unsubstituted alkyl groups, substituted or unsubstituted alkoxy groups, substituted or unsubstituted amino groups, substituted or unsubstituted aryl groups, and substituted or unsubstituted heterocyclic groups, and at least one of R3, R4, R9, and R10 is selected from substituted or unsubstituted aryl groups and substituted or unsubstituted heterocyclic groups.
    Type: Application
    Filed: July 26, 2011
    Publication date: May 23, 2013
    Applicant: CANON KABUSHIKI KAISHA
    Inventors: Tomonari Horikiri, Jun Kamatani, Masanori Muratsubaki
  • Patent number: 8445686
    Abstract: The present invention relates to novel 4-(4-pyridyl)-benzamides of the formula (I). The compounds I possess valuable therapeutic properties and are suitable, in particular, for treating diseases that respond to modulation of Rho kinases (ROCKs).
    Type: Grant
    Filed: August 26, 2008
    Date of Patent: May 21, 2013
    Assignee: AbbVie Inc.
    Inventors: Helmut Mack, Nicole Teusch, Bernhard K. Mueller, Wilfried Hornberger, Michael F. Jarvis, Daryl Sauer, Steve Swann, Jr., Dominique Bonafoux, Ryan Keddy, Adrian Donald Hobson, Anil Vasudevan
  • Patent number: 8367001
    Abstract: The present invention generally relates to luminescent and/or optically absorbing compositions and/or precursors to those compositions, including solid films incorporating these compositions/precursors, exhibiting increased luminescent lifetimes, quantum yields, enhanced stabilities and/or amplified emissions. The present invention also relates to sensors and methods for sensing analytes through luminescent and/or optically absorbing properties of these compositions and/or precursors. Examples of analytes detectable by the invention include electrophiles, alkylating agents, thionyl halides, and phosphate ester groups including phosphoryl halides, cyanides and thioates such as those found in certain chemical warfare agents. The present invention additionally relates to devices and methods for amplifying emissions, such as those produced using the above-described compositions and/or precursors, by incorporating the composition and/or precursor within a polymer having an energy migration pathway.
    Type: Grant
    Filed: November 15, 2010
    Date of Patent: February 5, 2013
    Assignee: Massachusetts Institute of Technology
    Inventors: Timothy M. Swager, Shi-Wei Zhang
  • Publication number: 20120264946
    Abstract: The present invention relates to a process for the preparation of compounds with (perfluoroalkyl)fluorohydrogenphosphate anion, and to compounds containing (perfluoroalkyl)fluorohydrogenphosphate anion and to the use thereof.
    Type: Application
    Filed: December 6, 2010
    Publication date: October 18, 2012
    Applicant: MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG
    Inventors: Nikolai (Mykola) Ignatyev, Michael Schulte, Anne Julia Bader, Berthhold Theo Hoge
  • Patent number: 8288588
    Abstract: The present invention relates to compounds of formula (I) wherein X, R1, R2, R3, R4 and R5 are as defined herein, which are useful for treating diseases which respond to CXCR2 receptor mediators. Pharmaceutical compositions that contain the compounds and processes for preparing the compounds are also described.
    Type: Grant
    Filed: June 21, 2011
    Date of Patent: October 16, 2012
    Assignee: Novartis AG
    Inventors: Urs Baettig, Anne-Marie D'souza, Peter Hunt, Neil John Press, Simon James Watson
  • Patent number: 8211820
    Abstract: The invention provides a catalyst composition for use in a cross-coupling reaction containing an iron or cobalt fluoride and a nitrogen-containing heterocyclic ring compound represented by General Formula (1A) or (1B), wherein R1 and R2 are same or different, and represent substituted or unsubstituted aryl group etc.; and R3 and R4 are same or different, and represent hydrogen etc., ?represents a single bond or a double bond, and X? represents a monovalent anion. The invention also provides a method for producing a cross-coupling compound by reacting an organic magnesium compound with an organic halogen compound in the presence of the catalyst composition.
    Type: Grant
    Filed: March 3, 2008
    Date of Patent: July 3, 2012
    Assignees: Kyoto University, Tosoh Finechem Corporation
    Inventors: Masaharu Nakamura, Takuji Hatakeyama
  • Patent number: 8193365
    Abstract: Compounds of Formula I, including pharmaceutically acceptable salts of the compounds, are CETP inhibitors, and are useful for raising HDL-cholesterol, reducing LDL-cholesterol, and for treating or preventing atherosclerosis. In the compounds of Formula 1, A1 and A2 are each an aromatic ring, a 5-6-membered heterocyclic ring, an aromatic ring fused to a heterocyclic ring, a phenyl ring fused to a heterocyclic ring, or a cycloalkyl ring.
    Type: Grant
    Filed: June 14, 2010
    Date of Patent: June 5, 2012
    Assignee: Merck Sharp & Dohme Corp.
    Inventors: Amjad Ali, Joann Bohn, Qiaolin Deng, Zhijian Lu, Peter J. Sinclair, Gayle Taylor, Christopher Thompson, Nazia Quraishi
  • Patent number: 8168830
    Abstract: The present invention relates to diionic liquid salts of dicationic or dianionic molecules, as well as solvents comprising such diionic liquids and the use of such diionic liquids as the stationary phase in a gas chromatographic column.
    Type: Grant
    Filed: January 31, 2007
    Date of Patent: May 1, 2012
    Assignee: Sigma-Aldrich Co. LLC
    Inventors: Daniel W. Armstrong, Jared Anderson
  • Publication number: 20120101278
    Abstract: A process for producing a biaryl compound, characterized by reacting an arylhydrazine compound, hydrogen peroxide and an aryl compound. When the reaction is conducted in the presence of a given metal or a compound of the metal or in the presence of a metal oxide obtained by reacting the given metal or a compound of the metal with hydrogen peroxide, then the yield of the biaryl compound is improved.
    Type: Application
    Filed: December 27, 2011
    Publication date: April 26, 2012
    Inventor: KOJI HAGIYA
  • Patent number: 8148533
    Abstract: Ionic liquids having melting points below about 100 C formed by reaction of a heterocyclic amine with about 2.8 and about 3.2 moles of anhydrous hydrogen fluoride per mole of amine nitrogen. Electrochemical devices having non-aqueous electrolytes containing the ionic liquids are also disclosed, as well as silicon oxide etching compositions containing the ionic liquids and etching methods in which silicon oxides are selectively removed by the etching compositions in the presence of aluminum.
    Type: Grant
    Filed: March 4, 2005
    Date of Patent: April 3, 2012
    Assignee: Honeywell International Inc.
    Inventors: Martin A. Paonessa, Rajiv R Singh, Valentine T Zuba, George A Shia, John A McFarland
  • Publication number: 20120077665
    Abstract: A catalyst system comprising a half-sandwich chromium complex, an activator support and an optional cocatalyst. A compound of formula Cp?Cr(Cl)2(Ln), where Cp? is ?5-C5H4CH2CH2CH?CH2 and Ln is pyridine, THF or diethylether. A compound of formula Cp?Cr(Cl)2(Ln), where Cp? is ?5-C5H4C(Me)2CH2CH2CH?CH2 and Ln is pyridine, THF or diethylether.
    Type: Application
    Filed: September 24, 2010
    Publication date: March 29, 2012
    Applicant: CHEVRON PHILLIPS CHEMICAL COMPANY LP
    Inventors: Errun DING, Albert P. MASINO, Joel L. MARTIN, Youlu YU
  • Publication number: 20120046471
    Abstract: This invention relates to a process for preparing functionalized aryl, heteroaryl, cycloalkenyl, or alkenyl compounds, by a transition-metal-catalyzed cross-coupling reaction of a substituted or unsubstituted aryl-X, heteroaryl-X, cycloalkenyl-X or alkenyl-X compound with an alkyl, alkenyl, cycloalkyl or cycloalkenyl halide, where X is a halide, diazonium, tosylate (p-toluenesulphonate), mesylate (methanesulphonate) or triflate (trifluoromethanesulphonate) leaving group.
    Type: Application
    Filed: September 14, 2011
    Publication date: February 23, 2012
    Applicant: SALTIGO GMBH
    Inventors: Mark Sundermeier, Matthias Gotta, Axel Jacobi von Wangelin, Waldermar Maximilian Czaplik
  • Publication number: 20120041209
    Abstract: Provided is a process for producing a high-purity pyridine compound from a crude pyridine compound that contains a diazine compound as an impurity, the method including a reaction step of reacting the crude pyridine compound with an aluminum hydride compound, and a distillation step of distilling the product obtained from the reaction step. The aluminum hydride compound preferably contains one or more compounds selected from lithium aluminum hydride and sodium aluminum hydride.
    Type: Application
    Filed: May 22, 2009
    Publication date: February 16, 2012
    Applicant: Air Water Inc.
    Inventors: Koichi Fukui, Takeshi Namekata, Ikuo Ito
  • Publication number: 20120020867
    Abstract: Disclosed is a method for producing “a salt or a complex comprising imide and an organic base”, characterized by reacting halogenated sulfuryl or halogenated phosphoryl with ammonia in the presence of an organic base. According to this method, a target imide compound can be produced in a high yield while significantly suppressing the production of by-products. Further, by reacting the obtained imide compound with an alkali metal hydroxide or an alkaline earth metal hydroxide, an imide metal salt can be easily derived.
    Type: Application
    Filed: March 29, 2010
    Publication date: January 26, 2012
    Applicant: Central Glass Company, Limited
    Inventors: Takayoshi Morinaka, Tsutomu Nanmyo
  • Patent number: 8093395
    Abstract: An object of the invention is to provide a novel sphingosine compound with an inhibitory activity against sphingomyelinase, and a method for producing the sphingosine compound. The novel sphingosine compound or a salt thereof according to the invention is represented by Formula (1): wherein one of R1 and R2 is hydrogen, and the other is a group represented by Formula (G): wherein n is 0 or 1; and R3 is hydrogen, C1-23 alkyl, C3-8 cycloalkyl, C2-6 alkenyl, C1-6 alkoxy, C3-8 cycloalkyloxy, phenyl, or furil.
    Type: Grant
    Filed: March 5, 2008
    Date of Patent: January 10, 2012
    Assignee: Otsuka Chemical Co., Ltd.
    Inventors: Mugio Nishizawa, Hiroshi Imagawa, Jun Sakurai, Masataka Oda
  • Patent number: 8084614
    Abstract: GnRH receptor antagonists are disclosed which have utility in the treatment of a variety of sex-hormone related conditions in both men and women. The compounds of this invention have the structure, wherein R1a, R1b, R1c, R1d, R2, R2a, and A are as defined herein, including stereoisomers, esters, solvates and pharmaceutically acceptable salts thereof. Also disclosed are compositions containing a compound of this invention in combination with a pharmaceutically acceptable carrier, as well as methods relating to the use thereof for antagonizing gonadotropin-releasing hormone in a subject in need thereof.
    Type: Grant
    Filed: April 4, 2008
    Date of Patent: December 27, 2011
    Assignee: Neurocrine Biosciences, Inc.
    Inventors: Graham Beaton, Mi Chen, Timothy Richard Coon, Todd Ewing, Wanlong Jiang, Richard Lowe, Willy Moree, Nicole Smith, Warren Wade, Liren Zhao, Yun-fei Zhu, Martin Rowbottom, Neil Ashweek
  • Publication number: 20110311884
    Abstract: The invention relates to a pentacyclic anion salt and to the use thereof in electrolyte compositions. The compound comprises an inorganic, organic or organometallic cation M of valency m (1?m?3) and m anions corresponding to the formula (I) in which Rf is a —CFZ?Z? group in which Z? is F or a perfluoroalkyl group having from 1 to 3 carbon atoms, and Z? is an H, F or Cl group, an optionally fluorinated or perfluorinated alkoxy group having from 1 to 5 carbon atoms, an optionally fluorinated or perfluorinated oxaalkoxy group having from 1 to 5 carbon atoms or an optionally fluorinated or perfluorinated alkyl group having from 1 to 5 carbon atoms; Z? being other than F when Z? is F. An electrolyte composition comprises said salt in solution in a liquid solvent or a polymer solvent.
    Type: Application
    Filed: August 28, 2009
    Publication date: December 22, 2011
    Inventors: Michel Armand, Sylvie Grugeon, Stephane Laruelle, Maria Bukowska, Przemyslaw Szczecinski, Wladyslaw Wieczorek, Leszek Niedzicki, Bruno Scrosati, Stefania Panero, Priscilla Realle
  • Patent number: 8013165
    Abstract: The present invention is directed to ethanamine compounds, pharmaceutical compositions comprising the same, and methods of treating depression by administering the ethanamine compound.
    Type: Grant
    Filed: December 22, 2009
    Date of Patent: September 6, 2011
    Assignee: AstraZeneca AB
    Inventors: Michael Balestra, Peter Bernstein, Glen E. Ernst, William Frietze, John P McCauley, Lihong Shen, David Nugiel
  • Publication number: 20110124755
    Abstract: The invention relates to a polyisocyanurate comprising isocyanurate rings linked by linker groups coupled to the nitrogen atoms of said rings. The polyisocyanurate may be microporous or mesoporous or both microporous and mesoporous.
    Type: Application
    Filed: April 9, 2009
    Publication date: May 26, 2011
    Applicant: AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH
    Inventors: Yugen Zhang, Jackie Y. Ying, Siti Nurhanna Binte Riduan
  • Publication number: 20110092711
    Abstract: Subject of the invention is a dehydrogenation catalyst for dehydrogenating methylpiperidine to methylpyridine. Subject of the invention are also methods for preparing the catalysts obtained thereby and methods, in which the catalysts are used.
    Type: Application
    Filed: October 13, 2010
    Publication date: April 21, 2011
    Inventors: Daniel Pianzola, Walter Siegrist
  • Publication number: 20110082166
    Abstract: This invention relates to novel 4-benzhydryl-tetrahydro-pyridine derivatives of Formula (I), any of its stereoisomers or any mixture of its stereoisomers, or an N-oxide thereof, or a pharmaceutically acceptable salt thereof, wherein Ra represents hydrogen or C1-6-alkyl; Rband Rc independent of each other represent a phenyl group, which phenyl group is optionally substituted with one or more substituents independently selected from the group consisting of halo, trifluoromethyl, trifluoromethoxy, cyano, C1-6-alkoxy and methylenedioxo useful as monoamine neurotransmitter re-uptake inhibitors. In other aspects the invention relates to the use of these compounds in a method for therapy and to pharmaceutical compositions comprising the compounds of the invention.
    Type: Application
    Filed: February 27, 2009
    Publication date: April 7, 2011
    Applicant: NEUROSEARCH A/S
    Inventors: Dan Peters, John Paul Redrobe, Elsebet Ostergaard Nielsen
  • Patent number: 7915424
    Abstract: The present invention is directed toward pyridyl derivatives of formula (I) as antagonists of the mGlu5 receptor.
    Type: Grant
    Filed: March 9, 2005
    Date of Patent: March 29, 2011
    Assignee: Eli Lilly and Company
    Inventors: Francisco Javier Agejas-Chicharro, Bruce Anthony Dressman, Jose Antonio Martinez Perez, James Allen Monn, Mohammad Sadegh Zia-Ebrahimi, Sonia Gutierrez Sanfeliciano, Steven Marc Massey, Steven Scott Henry
  • Publication number: 20110031487
    Abstract: A compound for an organic thin film transistor having a structure shown by the following formula (1): X1-L-Ar-L-X2??(1) wherein L is —C?C—, or —CH?CH— in a trans configuration, X1 and X2 are independently a substituted or unsubstituted aromatic heterocyclic group having 5 to 60 ring atoms, and their bonding positions to L are in heterocycles, Ar is a substituted or unsubstituted aromatic hydrocarbon group having 6 to 60 ring carbon atoms, or a substituted or unsubstituted aromatic heterocyclic group having 5 to 60 ring atoms, and at least one of X1, X2 and Ar is a bi- or higher-fused ring.
    Type: Application
    Filed: April 2, 2009
    Publication date: February 10, 2011
    Applicant: Idemitsu Kosan Co., Ltd.
    Inventors: Masatoshi Saito, Yuki Nakano, Hiroaki Nakamura
  • Publication number: 20110003992
    Abstract: A quaternary nitrogen-containing corrosion inhibitor of formula wherein is an aromatic, nitrogen-containing ring of 5 to 14 ring atoms, optionally containing an additional N, O or S ring atom and optionally substituted with one or more alkyl, alkenyl, aryl, arylalkyl, cycloalkyl, amino, aminoalkyl, alkoxy, hydroxylalkyl, or cyano groups, or a mixture thereof; Y is a group of formula —OC(O)R1 or —C(O)R1; L is C1-C10 alkyl, C2-C10 alkenyl or a group of formula —CH2CH(OR2)CH2—; R1 is C8-C20 alkyl or C8-C20 alkenyl; R2 is H or —C(O)R1; R3 and R4 are independently selected from H, alkyl, alkenyl, amino, alkoxy, hydroxylalkyl and cyano; and X is Br, Cl or I is particularly useful for inhibiting corrosion in oil and gas field applications.
    Type: Application
    Filed: September 15, 2010
    Publication date: January 6, 2011
    Inventor: Laxmikant Tiwari
  • Publication number: 20100331540
    Abstract: A method for producing a compound having a deuterated aromatic ring or heterocyclic ring according to the invention includes heating a compound having an aromatic ring or heterocyclic ring in the presence of heavy water, a transition metal and a metal which generates deuterium. As the metal which generates deuterium, at least one metal selected from the group consisting of aluminum, magnesium, zinc, iron, lead and tin is preferred. As the transition metal, at least one metal selected from the group consisting of platinum, palladium, ruthenium and rhodium is preferred. The heating is preferably carried out by microwave irradiation.
    Type: Application
    Filed: January 30, 2009
    Publication date: December 30, 2010
    Inventors: Haruki Shimodaira, Toshifumi Abe, Akira Miyazawa, Yuji Kawanishi, Taichi Abe
  • Publication number: 20100240900
    Abstract: The carbon nanomaterials and methods relate to methods for causing carbon nanospheres to be readily dispersible in a material. The carbon nanospheres are rendered dispersible using a cationic surfactant. The surfactant includes one or more cationic group that can bond to the surface of the carbon nanospheres, without detrimentally affecting the unique properties of carbon nanospheres. The dispersible carbon nanospheres can be dried (i.e., solvent is driven off) while maintaining their dispersibility in solvents and other materials.
    Type: Application
    Filed: March 23, 2009
    Publication date: September 23, 2010
    Applicant: HEADWATERS TECHNOLOGY INNOVATION, LLC
    Inventors: Cheng Zhang, Gaurang Bhargava, Bing Zhou
  • Patent number: 7790915
    Abstract: A liquid crystal (LC) compound having generally required physical properties, low viscosity, proper optical anisotropy, proper dielectric anisotropy and good compatibility with other LC compounds is described. An LC composition including the compound and an LCD device including the composition are also described. The compound is expressed by formula (1a): wherein the ring A1 and the ring A2 are independently 1,4-phenylene, pyridine-2,5-diyl, pyrimidine-2,5-diyl or naphthalene-2,6-diyl, in which any hydrogen can be replaced by halogen; Z1, Z2 and Z3 are independently a single bond, —(CH2)2—, —(CH2)4—, —CH?CH—, —C?C—, —CF2O—, —OCF2—, —COO— or —OCO—; Xa, Xb, Xc, Xd, Xe and Xf are independently hydrogen or fluorine; Y is —OCH2F, —OCHF2, —OCF3, —SCH2F, —SCHF2, —SCF3, —CH2F, —CHF2, —CF3, fluorine or chlorine; La and Lb are independently hydrogen or fluorine; and “l” and “m” are independently equal to 0 or 1.
    Type: Grant
    Filed: September 6, 2006
    Date of Patent: September 7, 2010
    Assignees: Chisso Petrochemical Corporation, Chisso Corporation
    Inventors: Tomoyuki Kondou, Shuichi Matsui, Keiji Kimura
  • Patent number: 7786043
    Abstract: The invention relates to 2-(pyridin-2-yl)-pyrimidine compounds of general formula (I) and their use for controlling pathogenic fungi and as plant protection products that, as an active constituent, contain compounds of this type: In general formula (I), k represents 0, 1, 2, 3; m represents 0, 1, 2, 3, 4 or 5; n represents 1, 2, 3, 4 or 5; R1, independent of one another, represents halogen, OH, CN, NO2, C1-C4 alkyl, C1-C4 alkyl halide, C1-C4 alkoxy, C1-C4 alkoxy halide, C2-C4 alkenyl, C2-C4 alkynyl, C3-C8 cycloalkyl, C1-C4 alkoxy-C1-C4 alkyl, amino, phenoxy, which is optionally substituted by halogen or C1-C4 alkyl, NHR, NR2, C(Ra)?N—ORb, S(?O)pA1 or C(?O)A2, or two radicals R1 bound to adjacent carbon atoms can, together, also represent a group —O-Alk-O—, wherein Alk represents a linear or branched C1-C4 alkylene, and 1, 2, 3 or 4 hydrogen atoms can also be replaced by halogen; R2 represents C1-C4 alkyl halide, C1-C4 alkoxy, C1-C4 alkoxy halide, hydroxy, halogen, CN or NO2; whereby R2 can also represent
    Type: Grant
    Filed: July 22, 2005
    Date of Patent: August 31, 2010
    Assignee: BASF Aktiengesellschaft
    Inventors: Wassilios Grammenos, Thomas Grote, Carsten Blettner, Markus Gewehr, Udo Hünger, Bernd Müller, Joachim Rheinheimer, Peter Schäfer, Frank Schieweck, Anja Schwögler, Ulrich Schöfl, Harald Köhle, Siegfried Strathmann, Maria Scherer, Reinhard Stierl, Jan Rether
  • Patent number: 7772198
    Abstract: The invention concerns pharmaceutical formulas designed for the treatment of diseases related to CFTR channel dysfunction, such as cystic fibrosis, asthma or diarrhoea. These formulas contain a molecule, coming in the form of a zwitterion at physiological pH, with the general formula: where X?N or P; and Y?O or S.
    Type: Grant
    Filed: April 21, 2006
    Date of Patent: August 10, 2010
    Assignees: Centre National de la Recherche Scientifique, Universite Joseph Fourier, Universite de Poitiers
    Inventors: Jean-Luc Decout, Christel Routaboul, Frederic Becq, Caroline Norez
  • Publication number: 20100137595
    Abstract: Use vaginal odorant compounds for controlling motile cell chemotaxis.
    Type: Application
    Filed: June 27, 2008
    Publication date: June 3, 2010
    Applicant: Fraunhofer-Gesellshcaft zur Forderung der angewandten Forschung e.V.
    Inventor: Andrea Büttner
  • Patent number: 7705011
    Abstract: An object of the present invention is to provide an agent for use in the effective treatment and prevention of endometriosis and uterine adenomyosis. The present invention relates to an agent for use in the treatment and prevention of endometriosis or uterine adenomyosis, comprising, as an active ingredient, a compound selected from the group consisting of 3-ethylpyridine, 3-methylpyridine, 2-ethylpyridine, and 2-methylpyridine.
    Type: Grant
    Filed: March 15, 2006
    Date of Patent: April 27, 2010
    Inventors: Masao Igarashi, Toshio Igarashi, Shigeo Igarashi
  • Publication number: 20100094018
    Abstract: The invention provides a catalyst composition for use in a cross-coupling reaction containing an iron or cobalt fluoride and a nitrogen-containing heterocyclic ring compound represented by General Formula (1A) or (1B), wherein R1 and R2 are same or different, and represent substituted or unsubstituted aryl group etc.; and R3 and R4 are same or different, and represent hydrogen etc., represents a single bond or a double bond, and X? represents a monovalent anion. The invention also provides a method for producing a cross-coupling compound by reacting an organic magnesium compound with an organic halogen compound in the presence of the catalyst composition.
    Type: Application
    Filed: March 3, 2008
    Publication date: April 15, 2010
    Applicants: KYOTO UNIVERSITY, TOSOH FINECHEM CORPORATION
    Inventors: Masaharu Nakamura, Takuji Hatakeyama
  • Publication number: 20100051509
    Abstract: Ionic liquids of the general formula C+A? where C+ represents an organic cation, specifically, but not limited to the imidazolium, pyridinium, isoquinolinium, ammonium types, which have aliphatic and aromatic substituents, while A? represents a carboxylate, aromatic and aliphatic anion. The ionic liquids are synthesized under conventional heating or microwave irradiation This invention is also related to the application of ionic liquids to remove sulfur compounds of naphthas through a liquid-liquid extraction and the recovery and reuse of ionic liquids by the application of heat, reduced pressure and washing with solvents.
    Type: Application
    Filed: August 27, 2009
    Publication date: March 4, 2010
    Applicant: INSTITUTO MEXICANO DEL PETROLEO
    Inventors: Rafael Martinez Palou, Natalya Victorovna Likhanova, Eugenio Alejandro Flores Oropeza, Diego Javier Guzman Lucero
  • Patent number: 7635700
    Abstract: Provided are 5-substituted quinazolinone compounds, for example, of formula (I), and pharmaceutically acceptable salts, solvates, clathrates, stereoisomers, and prodrugs thereof. Methods of use for treating angiogenesis or cytokine related disorders, and pharmaceutical compositions of these compounds are disclosed.
    Type: Grant
    Filed: September 26, 2007
    Date of Patent: December 22, 2009
    Assignee: Celgene Corporation
    Inventors: George W. Muller, Hon-Wah Man
  • Patent number: 7618972
    Abstract: The present invention relates to a class of substituted triazoles of formula (I) with activity as oxytocin antagonists, uses thereof, processes for the preparation thereof and compositions containing said inhibitors. These inhibitors have utility in a variety of therapeutic areas including sexual dysfunction, particularly premature ejaculation (P.E.).
    Type: Grant
    Filed: March 8, 2006
    Date of Patent: November 17, 2009
    Assignee: Pfizer Inc
    Inventor: Andrew Antony Calabrese