Tetracyclo Ring System Having The Thiazole Ring As One Of The Cyclos Patents (Class 548/149)
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Patent number: 9683114Abstract: A monomer for a hardmask composition, a hardmask composition, and a method of forming patterns, the monomer being represented by the following Chemical Formula 1:Type: GrantFiled: January 30, 2015Date of Patent: June 20, 2017Assignee: SAMSUNG SDI CO., LTD.Inventors: Hea-Jung Kim, Sung-Hwan Kim, Youn-Hee Nam, Yun-Jun Kim, Joon-Young Moon, Hyun-Ji Song, Yong-Woon Yoon, Chung-Heon Lee
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Publication number: 20140364385Abstract: An isolated compound of Formula I and salts thereof are provided: wherein X is Cl or Br. A compound isolated from Actinomadura and having a chemical formula of C43H69ClN4O10S2 or C43H69BrN4O10S2 is also provided. Compositions including the compounds and methods of using the compounds to treat fungal infections including those such as Candida are also disclosed.Type: ApplicationFiled: June 9, 2014Publication date: December 11, 2014Inventors: Timothy BUGNI, Thomas WYCHE, David ANDES, Douglas BRAUN
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Publication number: 20140252324Abstract: Provided is an organic light-emitting diode including a compound of Formula 1 below: wherein a detailed description of a substituent in Formula 1 above is defined as described in the detailed description.Type: ApplicationFiled: August 5, 2013Publication date: September 11, 2014Inventor: Jung-Sub LEE
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Publication number: 20140256936Abstract: A compound according to Formula IA and IB, reversibly convertible under photochromic and electrochromic conditions between a ring-open isomer A and a ring-closed isomer B is provided. For substitutent groups, Z is N, O or S; each R1 is independently selected from the group consisting of H, or halo; each R2 is independently selected from the group consisting of H, halo, a polymer backbone, alkyl or aryl; or, when both R2 together form —CH?CH— and form part of a polymer backbone; each R3 is independently selected from the group consisting of H, halo, alkyl, alkoxy, thioalkyl or aryl; each R4 is aryl; and each R5 is independently selected from the group consisting of H, halo, alkyl, alkoxy, thioalkyl or aryl.Type: ApplicationFiled: September 28, 2012Publication date: September 11, 2014Applicant: SWITCH MATERIALS, INC.Inventors: Neil Robin Branda, Jeremy Graham Finden, Simon James Gauthier, Ali Hayek, Kyle Andrew Hope-Ross, James Daniel Senior, Andreea Spantulescu, Serguei Sviridov
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Publication number: 20140027755Abstract: The present invention relates to an electronic device comprising one or more compounds of a formula (I) or (II). Furthermore, the invention encompasses the use of a compound of the formula (I) or (II) in an electronic device, and the provision of certain compounds of the formula (I) or (II).Type: ApplicationFiled: March 15, 2012Publication date: January 30, 2014Applicant: Merck Patent GmbH Patents & Scientific InformationInventors: Teresa Mujica-Fernaud, Christof Pflumm, Irina Martynova
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Publication number: 20120196852Abstract: The invention is directed towards novel naphthoquinone and naphthothiazole compounds, and methods of treating disorders related to MetAP, including tuberculosis and bacterial infection, using various naphthoquinone, hydroxyquinonline, and naphthothiazole compounds.Type: ApplicationFiled: August 5, 2010Publication date: August 2, 2012Applicant: THE JOHNS HOPKINS UNIVERSITYInventors: Jun O. Liu, Omonike Arike Olaleye, Shridhar Bhat
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Publication number: 20120001157Abstract: Disclosed are an organic composition including a compound represented by Chemical Formula 1, and an organic light emitting device including the composition. In Chemical Formula 1, A1, A2, A3, A4, B1, B2, B3 and B4 are independently selected from hydrogen, a C1 to C20 alkyl group, a C1 to C20 alkenyl group, an amino group, a C1 to C20 ether group, a C1 to C20 carboxyl group, a C1 to C20 ester group, a nitro group, a cyano group, a C3 to C30 aromatic group, and a halogen-containing group, provided that at least one of A1 to A4 and at least one of B1 to B4 are a substituted or unsubstituted aromatic group and form a fused ring structure by being bound to an adjacent substituent, M is a divalent or trivalent metal, X is oxygen (O) or sulfur (S), and y is 2 or 3.Type: ApplicationFiled: June 20, 2011Publication date: January 5, 2012Applicant: SAMSUNG MOBILE DISPLAY CO., LTD.Inventors: Yuji HAMADA, Kwan-Hee LEE
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Publication number: 20110130305Abstract: Provided are dyes and compositions which are useful in a number of applications, such as the detection and monitoring protein aggregation, kinetic studies of protein aggregation, neurofibrillary plaques analysis, evaluation of protein formulation stability, protein thermal stability shift assay and analysis of molecular chaperone activity. These dyes and compositions are also useful as probes in nucleic acid and protein detection.Type: ApplicationFiled: November 30, 2009Publication date: June 2, 2011Inventors: Wayne Forrest Patton, Sergiy M. Yarmoluk, Praveen Pande, Vladyslava Kovalska, Lijun Dai, Kateryna Volkova, Jack Coleman, Mykhaylo Losytskyy, Anthony Ludlum, Anatoliy Balanda
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Publication number: 20110006287Abstract: A copolymer comprising at least one donor monomer and at least one acceptor monomer is described. The polymer may optionally further comprise, consist or consist essentially of at least one additional comonomer. Various donor monomers, acceptor monomers and additional comonomers are also described. The polymer is useful in the manufacture of microelectronic devices such as optoelectronic devices.Type: ApplicationFiled: March 18, 2010Publication date: January 13, 2011Inventors: Wei You, Shengqiang Xiao
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Patent number: 7262302Abstract: The present invention relates to derivatives of 1-thia-3-aza-dibenzoazulene class, to their pharmacologically acceptable salts and solvates, to processes and intermediates for the preparation thereof as well as to their antiinflammatory effects, especially to the inhibition of tumour necrosis factor-? (TNF-?) production and the inhibition of interleukin-1 (IL-1) production as well as to their analgetic action.Type: GrantFiled: May 20, 2003Date of Patent: August 28, 2007Assignee: GlaxoSmithKline Istrazivacki Centar Zagreb, D.O.O.Inventors: Mladen Mercep, Milan Mesic, Marina Modric, Dijana Pesic, Davor Kidemet
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Patent number: 7161010Abstract: Disclosed is a compound represented by the following formula (I): wherein Z1 represents an atomic group necessary to form a 5- or 6-membered nitrogen-containing heterocyclic ring; Z2 represents an atomic group necessary to form a 5- or 6-membered heterocyclic ring, Z2 may further be substituted, or may be condensed with a hetero ring of a benzene ring; R1 represents a hydrogen atom, a halogen atom, a mercapto group, an alkyl group, an alkenyl group, an aryl group, an alkylthio group, an alkenylthio group, or an arylthio group; L1 and L2 each represents a methine group; pi represents 0 or 1; V1 represents a substituent; and n represents 0, 1 or 2, and when n represents 2, a plurality of V1 may be the same or different.Type: GrantFiled: August 1, 2003Date of Patent: January 9, 2007Assignee: Fuji Photo Film Co., Ltd.Inventors: Katsumi Kobayashi, Takashi Katoh, Junji Nishigaki
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Patent number: 7122534Abstract: The present invention relates to compounds of formula (I) and their pharmaceutically acceptable salts, wherein R1, R2, R3 and Z are as defined herein, intermediates in the synthesis of such compounds, pharmaceutical compositions containing such compounds and methods of using such compounds in the treatment of neurological and psychological disorders.Type: GrantFiled: January 23, 2004Date of Patent: October 17, 2006Assignee: Pfizer IncInventor: Jotham Wadsworth Coe
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Publication number: 20040209117Abstract: The present invention is an organic light emitting device (OLED) comprising an anode, a cathode and a luminescent region provided between the anode and the cathode. The luminescent region comprises an electron injection and transporting zone and at least one of a hole injection and transporting zone and a mixed charge transport layer. One or both of the electron injection and transporting zone and the mixed charge transporting layer comprises an azole compound represented by formula I and/or II. The provision of the novel azole compounds of the invention as electron transport materials within an organic electroluminescent device advantageously reduces power consumption and increases power conversion efficiency within the device and as such, are suitable for a variety of display applications.Type: ApplicationFiled: November 6, 2003Publication date: October 21, 2004Applicant: Xerox CorporationInventors: Hany Aziz, George Vamvounis, Nan-Xing Hu, Zoran D. Popovic, Jennifer A. Coggan
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Patent number: 6730793Abstract: Provided are chromophores of the formula Q—(—L—Z)x, wherein x is 2 or 3, wherein Q is selected from the group consisting of wherein L is wherein R is an alkyl group having 1 to 20 carbon atoms, and wherein Z is selected from the group consisting ofType: GrantFiled: June 13, 2002Date of Patent: May 4, 2004Assignee: The United States of America as represented by the Secretary of the Air ForceInventors: Ramamurthi Kannan, Loon-Seng Tan, Bruce A. Reinhardt, Richard A. Vaia
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Patent number: 6706702Abstract: The present invention relates to compounds of formula (I) and their pharmaceutically acceptable salts, wherein R1, R2, R3 and Z are as defined herein, intermediates in the synthesis of such compounds, pharmaceutical compositions containing such compounds and methods of using such compounds in the treatment of neurological and psychological disorders.Type: GrantFiled: August 13, 2002Date of Patent: March 16, 2004Assignee: Pfizer Inc.Inventor: Jotham Wadsworth Coe
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Patent number: 6667405Abstract: Disclosed is a compound represented by the following formula (I): wherein Z1 represents an atomic group necessary to form a 5- or 6-membered nitrogen-containing heterocyclic ring; Z2 represents an atomic group necessary to form a 5- or 6-membered heterocyclic ring, Z2 may further be substituted, or may be condensed with a hetero ring or a benzene ring; R1 represents a hydrogen atom, a halogen atom, a mercapto group, an alkyl group, an alkenyl group, an aryl group, an alkylthio group, an alkenylthio group, or an arylthio group; L1 and L2 each represents a methine group; p1 represents 0 or 1; V1 represents a substituent; and n represents 0, 1 or 2, and when n represents 2, a plurality of V1 may be the same or different.Type: GrantFiled: November 1, 2001Date of Patent: December 23, 2003Assignee: Fuji Photo Film Co., Ltd.Inventors: Katsumi Kobayashi, Takashi Katoh, Junji Nishigaki
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Patent number: 6288094Abstract: The invention relates to polycyclic thiazolidin-2-ylidene amines and their physiologically tolerated salts and physiologically functional derivatives. Polycyclic thiazolidin-2-ylidene amines of the formula I, in which the radicals have the stated meanings, and their physiologically tolerated salts and processes for their preparation are described. The compounds are suitable, for example as anorectics and in the treatment or prophylaxis of type II diabetes.Type: GrantFiled: January 31, 2001Date of Patent: September 11, 2001Assignee: Aventis Pharma Deutschland GmbHInventors: Gerhard Jähne, Karl Geisen, Hans-Jochen Lang, Martin Bickel
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Patent number: 6288093Abstract: The invention relates to polycyclic thiazolidin-2-ylidene amines and their physiologically tolerated salts and physiologically functional derivatives. Polycyclic thiazolidin-2-ylidene amines of the formula I, in which the radicals have the stated meanings, and their physiologically tolerated salts and processes for their preparation are described. The compounds are suitable, for example as anorectics and in the treatment or prophylaxis of type II diabetes.Type: GrantFiled: October 27, 2000Date of Patent: September 11, 2001Assignee: Aventis Pharma Deutschland GmbHInventors: Gerhard Jähne, Karl Geisen, Hans-Jochen Lang, Martin Bickel
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Patent number: 6277995Abstract: A process for preparing a compound represented by formula (I), wherein R1 represents straight-chain or branched C1-5 alkyl, C1-5 haloalkyl, or C3-6 cycloalkyl, and R2 represents C1-3 alkyl or C1-3 haloalkyl.Type: GrantFiled: May 10, 2000Date of Patent: August 21, 2001Assignee: LG Chemical Ltd.Inventors: Goon-Ho Joe, Ju-Young Lee, Sang-Who Lee, Jae-Hoon Jeon, Kun-Tai Kim, Hwan-Sung Cheon
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Patent number: 6159996Abstract: Polycyclic thiazolidin-2-ylidene amines and their physiologically tolerable salts and physiologically functional derivatives of the formula I ##STR1## in which the radicals have the meanings indicated, and their physiologically tolerable salts and a process for their preparation are described. The compounds are suitable, for example, as anorectics.Type: GrantFiled: July 12, 1999Date of Patent: December 12, 2000Assignee: Aventis Pharma Deutschland GmbHInventors: Gerhard Jaehne, Karl Geisen, Hans Jochen Lang
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Patent number: 6043373Abstract: A thiazole compound represented by general formula (I), wherein R is hydrogen atom, a hydroxy group, a straight or branched C.sub.1 -C.sub.6 lower alkyl group, a C.sub.1 -C.sub.4 lower alkoxy group, phenyl group, a phenyl group having one to three substituents selected from a group consisting of a C.sub.1 -C.sub.4 lower alkyl group, a C.sub.1 -C.sub.4 lower alkoxy group, fluorine, chlorine, bromine and an amino group, a C.sub.1 -C.sub.5 alkylphenyl group, a phenyl group having one to three substituents selected from a group consisting of a C.sub.1 -C.sub.4 lower alkyl group, a C.sub.1 -C.sub.4 lower alkoxy group, fluorine, chlorine, bromine and an amino group, a substituted or unsubstituted guanidino group, or an amino group having a general formula: NR.sub.3 R.sub.4 in which R.sub.3 and R.sub.4, identical to or different from each other, represent independently a hydrogen atom, a C.sub.1 -C.sub.6 lower alkyl group, a C.sub.3 -C.sub.Type: GrantFiled: July 3, 1997Date of Patent: March 28, 2000Assignee: Yungjin Pharmaceutical Co., Ltd.Inventors: Han Yong Yoo, Kae Jong Chung, Jun Pyo Chai, Man Sik Chang, Sung Gyu Kim, Wahn Soo Choi, Young Hun Kim, Jae Kwang Chun, Young Kuk Chung, Young Heui Kim, Jang Hoon Paek, Kwi Hyon Seo, Dae Pil Kang
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Patent number: 5612356Abstract: A heterocycle-containing carbonic acid derivative represented by the following general formula (I): ##STR1## or a physiologically acceptable salt thereof which exhibits an excellent preventive and therapeutic effect against various diseases, and an intermediate which is useful for the production of the heterocycle-containing carbonic acid derivative.Type: GrantFiled: April 25, 1995Date of Patent: March 18, 1997Assignee: Eisai Co., Ltd.Inventors: Hiroyuki Yoshimura, Mitsuo Nagai, Shigeki Hibi, Koichi Kikuchi, Ieharu Hishinuma, Junichi Nagakawa, Makoto Asada, Norimasa Miyamoto, Takayuki Hida, Aichi Ogasawara, Isao Yamatsu
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Patent number: 5569655Abstract: Substitutued heterocyclylisoquinolinium salts, pharmaceutical compositions containing them and methods for the treatment or prevention of neurodegenerative disorders or neurotoxic injuries utilizing them.Type: GrantFiled: July 29, 1994Date of Patent: October 29, 1996Assignee: Sterling Winthrop Inc.Inventors: John A. Dority, Jr., William G. Earley, Virendra Kumar, John P. Mallamo, Matthew S. Miller, Chakrapani Subramanyam
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Patent number: 5565479Abstract: Condensed thiazole derivatives useful as 5-HT.sub.3 receptor agonists are provided and can be represented by the following formula (I) or a pharmaceutically acceptable salt thereof, a process for the production thereof and a pharmaceutical composition thereof: ##STR1## wherein R, A, L.sub.1, L.sub.2, L, and R.sup.1 -R.sup.Type: GrantFiled: April 28, 1995Date of Patent: October 15, 1996Assignee: Yamanouchi Pharmaceutical Co., Ltd.Inventors: Kiyoshi Iwaoka, Hiroyuki Koshio, Hiroyuki Ito, Keiji Miyata, Mitsuaki Ohta
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Patent number: 5414091Abstract: There are disclosed dye-providing compounds comprising color coupler dyes substituted on the phenylene diamine portion with one or two cyclic 1,3-sulfur-nitrogen groups. The dye-providing compounds are capable of releasing the coupler dye upon cleavage in the presence of silver ions or a soluble silver complex. The dye-providing compounds are useful as image-forming materials in color thermographic, photothermographic and other photographic processes.Type: GrantFiled: May 23, 1994Date of Patent: May 9, 1995Assignee: Polaroid CorporationInventors: Efthimios Chinoporos, Robert H. Pauze, David P. Waller, David C. Whritenour
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Patent number: 5329006Abstract: Chromogenic lactam compounds of the formula ##STR1## in which the ring A is an aromatic or heteroaromatic radical which has 6 ring atoms and may contain a fused aromatic ring, it being possible for both the ring A and the fused ring to be substituted;the ring B is an unsubstituted or substituted benzene ring;Z is ##STR2## R is hydrogen; unsubstituted or substituted C.sub.1 -C.sub.12 alkyl, cycloalkyl having 5 to 10 carbon atoms; unsubstituted or substituted aryl or aralkyl; C.sub.1 -C.sub.12 acyl; N-(lower alkyl)carbamoyl; or N-arylcarbamoyl which is unsubstituted or substituted on the ring;Q is C.sub.1 -C.sub.12 alkylene, aryl-C.sub.1 -C.sub.4 alkylene, 1,2-cycloalkylene, 1,2- or 1,8-arylene or aralkylene; andX.sub.1 and X.sub.2, independently of one another, are each hydrogen; unsubstituted or substituted alkyl having a maximum of 12 carbon atoms; acyl having 1 to 8 carbon atoms; cycloalkyl having 5 to 10 carbon atoms; or unsubstituted or ring-substituted aralkyl or aryl; or (X.sub.1 and X.sub.Type: GrantFiled: September 6, 1991Date of Patent: July 12, 1994Assignee: Ciba-Geigy CorporationInventors: Hans Baumann, Ian J. Fletcher
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Patent number: 5204467Abstract: Photopolymerizable compositions containing photoinitiator systems that absorb in the visible are disclosed.Type: GrantFiled: December 20, 1991Date of Patent: April 20, 1993Assignee: E. I. Du Pont de Nemours and CompanyInventor: William K. Smothers
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Patent number: 5180419Abstract: There are provided o-carboxy-(5-oxo-2-imidazolin-2-yl)benzo-(5-membered)-heterocyclic compounds and derivatives thereof and a method for the use therewith to control monocotyledenous and dicotyledenous plant species.Type: GrantFiled: November 22, 1991Date of Patent: January 19, 1993Assignee: American Cyanamid CompanyInventors: David M. Gange, Michael A. Guaciaro, Robert F. Doehner, Jr.
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Patent number: 5149819Abstract: Squarylium compounds having the following formula (I), ##STR1## and an optical information recording medium comprising a substrate, and a recording layer formed on the substrate, comprising a squarylium compound having formula (II) are disclosed: ##STR2##Type: GrantFiled: May 1, 1991Date of Patent: September 22, 1992Assignees: Ricoh Company, Ltd., Kyowa Hakko Kogyo Co., Ltd.Inventors: Tsutomu Satoh, Ikuo Shimizu, Yukiyoshi Ito
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Patent number: 4946955Abstract: A method for preparation of polycyclic 1,3-thiazolidines is described. The method comprises reacting a fluoride ion source, in a solvent, with an onium salt synthesized by the reaction of a nitrogenous heteroaromatic compound with a halomethyl trimethylsilylmethyl sulfide, the halomethyl trimethylsilylmethyl sulfide being selected from the group consisting of chloromethyl trimethylsilylmethyl sulfide, bromomethyl trimethylsilylmethyl sulfide, or iodomethyl trimethylsilylmethyl sulfide.Type: GrantFiled: September 9, 1988Date of Patent: August 7, 1990Assignee: Toray Silicone Company LimitedInventor: Akira Hosomi
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Patent number: 4895863Abstract: A compound selected from the group consisting of a compound of the formula ##STR1## wherein R.sub.1 is selected from the group consisting of ##STR2## R.sub.4, R.sub.5, R.sub.7 and R.sub.8 are individually selected from the group consisting of hydrogen and alkyl of 1 to 5 carbon atoms, R.sub.6 is selected from the group consisting of hydrogen, alkyl of 1 to 5 carbon atoms, phenyl, halogen, alkoxycarbonyl of 2 to 5 carbon atoms, cyano, ##STR3## R' and R" are individually alkyl of 1 to 5 carbon atoms, R.sub.2 and R.sub.3 together form a member of the group consisting of ##STR4## m is 1, 2 or 3, X.sub.1 and X.sub.2 are individually selected from the group consisting of hydrogen, alkyl of 1 to 5 carbon atoms, alkenyl of 2 to 5 carbon atoms, alkoxy of 1 to 5 carbon atoms, aralkoxy, aryloxy, halogen, azido and nitro or taken together form methylenedioxy and their non-toxic, pharmaceutically acceptable acid additon salts capable of treating memory disorders.Type: GrantFiled: October 18, 1988Date of Patent: January 23, 1990Assignee: Roussel UclafInventors: Charles J. R. Hedgecock, David P. Kay
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Patent number: 4889936Abstract: The invention concerns a process for preparng a thiazolo[3,2-a]benzimidazole of formula I ##STR1## in which formula n is 1 or 2, and R.sub.1 is hydrogen, lower alkyl, lower alkoxy, trifluoromethyl or halo, or a salt thereof which comprises dehydrating a compound of formula II, ##STR2## or a salt thereof wherein n and R, are a defined above, and COOR is an acid or ester function in the presence of an acid selected from sulphuric, sulphonic and phosphoric acid or mixtures thereof and if desired or required an inert solvent provided that if water is present then the amount of water is less than about 15% by volume of the acid, the reaction being carried out with heating if necessary.Type: GrantFiled: January 10, 1989Date of Patent: December 26, 1989Assignee: John Wyeth & Brotyher LimitedInventors: Robin G. Shepherd, Sie-Yearl Chai, Maynard E. Lichty, Arnold S. Milowsky
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Patent number: 4812574Abstract: The invention concerns a process for preparing a thiazolo[3,2-a]benzimidazole of formula I ##STR1## in which formula n is 1 or 2, and R.sub.1 is hydrogen, lower alkyl, lower alkoxy, trifluoromethyl or halo, or a salt thereof which comprises dehydrating a compound of formula II, ##STR2## or a salt thereof wherein n and R, are as defined above, and COOR is an acid or ester function in the presence of an acid selected from sulphuric, sulphonic and phosphoric acid or mixtures thereof and if desired or required an inert solvent provided that if water is present then the amount of water is less than about 15% by volume of the acid, the reaction being carried out with heating if necessary.Type: GrantFiled: December 23, 1987Date of Patent: March 14, 1989Assignees: John Wyeth & Brother Ltd., American Home Products CorporationInventors: Robin G. Shepherd, Sie-Yearl Chai, Maynard E. Lichty, Arnold S. Milowsky
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Patent number: 4795483Abstract: The invention provides certain herbicidal thiazolotriazole sulphonamides, processes for their preparation, and compositions containing them, the compounds being of the formula: ##STR1## where: R.sup.1 and R.sup.2, which may be the same or different, each represent hydrogen, hydroxy, halo, cyano, substituted or unsubstituted alkyl, alkoxy, alkenyloxy, alkynyloxy, aryl, aralkyl, heteroaryl or carbamoyl, or a group --COR.sup.a or --CO.sub.2 R.sup.a or where R.sup.a is hydrogen or alkyl; or R.sup.1 and R.sup.2 together represent an alkylene chain of 3 or 4 carbon atoms;R.sup.3 represents a substituted or unsubstituted aryl, heterocyclyl or benzheterocyclyl group; andR.sup.4 represents hydrogen, an alkali-metal atom, an ammonium group, a substituted or unsubstituted alkyl, alkenyl, alkynyl, acyl, alkoxycarbonyl or aralkyl group, a heterocyclic group, or a group of the formula: ##STR2## where R.sup.1 and R.sup.2 are as defined hereinbefore.Type: GrantFiled: April 28, 1987Date of Patent: January 3, 1989Assignee: Schering AgrochemicalsInventor: Peter S. Gates
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Patent number: 4794123Abstract: This invention relates to a method of treating ulcers or hypersecretion in a mammal which comprises administering a compound of formula ##STR1## or a pharmaceutically acceptable salt thereof wherein --B--B.sup.1 -- represents a chain of formula--CR.sup.5 .dbd.CR.sup.6 -- (Ib)or--(CHR.sup.5).sub.n --CR.sup.6 .dbd. (Ic);R represents an optionally substituted aryl or heteroaryl radical; R.sup.1, R.sup.2, R.sup.3 and R.sup.4 independently represent hydrogen, or a defined substituent or any adjacent pair of R.sup.1, R.sup.2, R.sup.3 and R.sup.4 together with the carbon atoms to which they are attached complete a five or six membered saturated or unsaturated carbocyclic or heterocyclic ring, said ring being optionally substituted by a defined substituent said heterocyclic ring having at least one heteroatom selected from oxygen, nitrogen and sulphur. Novel compositions and compounds of formula I are also disclosed.Type: GrantFiled: October 13, 1987Date of Patent: December 27, 1988Assignee: John Wyeth & Brother LimitedInventors: Roger Crossley, Peter J. Meade
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Patent number: 4732984Abstract: There are disclosed compounds of the formula ##STR1## wherein R.sup.1 and R.sup.2 are each, independently, hydrogen, lower alkyl, aryl or halo, or R.sup.1 and R.sup.2 taken together represent --CH.sub.2 --, --CH.sub.2 CH.sub.2 --, --O--, --NH--, ##STR2## where the dotted lines represent optional double bonds; R.sup.3, R.sup.4, R.sup.5 and R.sup.6 are each, independently, hydrogen, lower alkyl, aryl or halo;R.sup.7 is 2-pyridinyl, 2-pyrimidinyl, 2-pyrazinyl, 3-pyridazinyl or phenyl or any of the foregoing R.sup.7 moieties substituted by lower alkyl, trifluoromethyl, cyano, nitro or halo, with the proviso that when R.sup.1 and R.sup.2 taken together represent ##STR3## then R.sup.7 is other than 2-pyridinyl, 2-pyrimidinyl or substituted pyrimidin-2-yl;Z is --(CH.sub.2).sub.Type: GrantFiled: August 5, 1986Date of Patent: March 22, 1988Assignee: American Home Products CorporationInventors: Magid A. Abou-Gharbia, Guy A. Schiehser, Scott J. Childress
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Patent number: 4599410Abstract: Methine dyes are disclosed which contain a 2-halo or pseudohalo substituted 1,2,5-oxatellurazole ring fused with an aromatic nucleus, the aromatic nucleus being substituted with a methine linkage terminating in an auxochrome providing a conjugated resonance chromophore. The dyes can be formed by condensing a methine linkage precursor with a compound containing an oxatellurazole ring fused with an aromatic nucleus. The dyes are useful in optical recording elements and in photographic elements.Type: GrantFiled: February 19, 1985Date of Patent: July 8, 1986Assignee: Eastman Kodak CompanyInventor: Wolfgang H. H. Gunther
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Patent number: 4552684Abstract: An anthraquinonic dye of the formula ##STR1## is provided. When used as dichloric dyes in liquid crystalline color display elements, these dyes (1) have sufficient coloring ability in small amounts, (2) have a high dichloric ratio, (3) are fully soluble in liquid crystals, and (4) have excellent durability, are stable and do not degrade the performance of a display device upon long-term use.Type: GrantFiled: March 7, 1984Date of Patent: November 12, 1985Assignee: Mitsui Toatsu Chemicals, Inc.Inventors: Yasuyuki Yamada, Tsutomu Nishizawa, Tamio Mikoda, Tooru Miyahara, Masaharu Kikutsugi
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Patent number: 4347369Abstract: Hexahydronaphth[1',2':4,5]imidazo[2,1-b]thiazole and its derivatives of formula [I] ##STR1## (where X.sub.1 and X.sub.2 stand for hydrogen or halogen atoms; R represents a hydrogen atom, lower alkyl of 1 to 4 carbon atoms or lower alkyl substituted with a carboxyl given as --(CH.sub.2).sub.n COOH (n is an integral number of 1 to 3); A, B, C, and D symbolize the rings respectively and the configuration of rings B and C is trans) and their acid adducts, and a method of preparing them according to the chemical equation given below: ##STR2## (where X.sub.3 is a halogen atom). These compounds have immunostimulative activity.Type: GrantFiled: August 15, 1980Date of Patent: August 31, 1982Assignee: Teijin LimitedInventors: Takeshi Hara, Yasutaka Kayama
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Patent number: 4174397Abstract: Thiazolidine derivatives of the formula I ##STR1## in which the substituents R.sup.1 to R.sup.7 have the meanings as indicated in the following and which have in the free form or in the form of their non toxic acid addition salts valuable pharmaceutical properties, processes for preparing them, pharmaceutical preparations on the basis of these compounds and their use as medicines.Type: GrantFiled: September 6, 1977Date of Patent: November 13, 1979Assignee: Hoechst AktiengesellschaftInventors: Bernd Knabe, Hans-Jochen Lang, Ernold Granzer