Abstract: Aryl-mercapto-lower-alkanamides having the following formula ##STR1## wherein R.sup.1 is selected from the group consisting of phenyl, C.sub.1-4 -alkylphenyl, halophenyl, hydroxyphenyl, C.sub.1-4 -alkoxyphenyl, aminophenyl, acetamidophenyl, naphthyl, diphenyl; R.sup.2 and R.sup.3, independently represent hydrogen or C.sub.1-14 -alkyl; Y represents NR.sup.4 R.sup.5 wherein R.sup.4 and R.sup.5 independently represent hydrogen, C.sub.1 -6-alkyl, C.sub.2-3 -hydroxyalkyl, benzyl, anilyl, and taken together represent piperidyl or morpholinyl are useful for reducing cell sebum production in a mammal in the form of a topical cosmetic preparation.
Abstract: Compounds of the formula ##STR1## wherein R is thienyl, mono-, di- and trihalothienyl, furyl, 2-benzothiazolyl, pyridyl or chloropyridyl and their pharmaceutically acceptable salts are useful agents for combating fungal infections in animals, including humans.
Abstract: Tertiary amines may be quaternized by heating them with a sulfoalkylating agent of this invention to a temperature of from 100.degree. to 250.degree. C. The sulfoalkylating agents which are believed to be hydroxy alkane sulfonic acid sulfoalkyl esters are free from sultone and are prepared by heating a hydroxy alkane sulfonic acid of propane or butane or the corresponding sultone to a temperature in the region of from 80.degree. to 180.degree. C. in the presence of water in an amount of 1 to 4 moles per mole of hydroxy alkane sulfonic acid or alkane sultone.
Abstract: The invention relates to stilbene compounds of the formula ##STR1## wherein Q is hydrogen; a monocyclic 5- or 6-membered aromatic heterocyclic ring which is unsubstituted or substituted by non-chromophoric groups and which contains no fused benzene rings or one or two fused benzene rings; a bicyclic 9-membered aromatic heterocyclic ring or the radical --CH.dbd.C(R.sub.1)(R.sub.2), in which R.sub.1 is hydrogen, C.sub.1 -C.sub.6 alkyl which is unsubstituted or substituted by non-chromophoric groups, and R.sub.2 is alkoxycarbonyl containing altogether 2 to 7 carbons atoms, cyano, carboxyl, carbamoyl, phosphonic acid dialkyl ester, C.sub.1 -C.sub.6 alkyl or arylsulfonyl; or Q may also be ##STR2## R.sub.o is hydrogen or C.sub.1 -C.sub.6 alkyl, R is C.sub.1 -C.sub.6 alkyl which is unsubstituted or substituted by non-chromophoric groups, C.sub.2 -C.sub.5 alkenyl, C.sub.2 -C.sub.5 alkynyl, di(C.sub.1 -C.sub.4)alkylamino(C.sub.1 -C.sub.4)alkyl, C.sub.1 -C.sub.4 hydroxyalkyl, C.sub.1 -C.sub.
Abstract: Disclosed is a novel process and product involving the manufacture in advantageously high yields of imidazole compounds corresponding to the general formula: ##STR1## wherein a preferred embodiment of the process comprises contacting a diamine salt of the formula ##STR2## with a biscarbonyl compound of the structure ##STR3## in an acid medium, wherein R, R.sub.1 and R.sub.2 each represents hydrogen or any group which does not hinder the cyclization reaction or lead to degradation of the reactants or imidazole products, and A.sup.- is an anion equivalent such as that of mineral acids, sulfonic acids and carboxylic acids.
Abstract: Oxime ether derivatives of the formula (I): ##STR1## wherein Het is a monocyclic heteroaromatic group containing two hetero atoms at least one of which is nitrogen, or a bicyclic heteroaromatic group containing one or two hetero atoms at least one of which is nitrogen, Ar is a phenyl or a 5- or 6-membered monocyclic heteroaromatic group, and R is an alkyl, alkenyl, alkynyl, cyanoalkyl, carbamidoalkyl or aminoalkyl group, or N-oxides thereof, have anti-ulcer activity in the gastro-intestinal tract of mammals.
Abstract: A process for protecting cultivated plants against aggressive agricultural chemicals is described in which oxime derivatives of the formula ##STR1## are used as antidotes. Either the cultivated area for the cultivated plants or the cultivated plants themselves or parts of the plant (seeds, tubers, stem parts and the like), as desired, can be treated with these oxime derivatives, which are used as a dressing.
Type:
Grant
Filed:
August 28, 1979
Date of Patent:
August 31, 1982
Assignee:
Ciba-Geigy Corporation
Inventors:
Alfons Lukaszczyk, Henry Martin, Peter J. Diel, Werner Fory, Karl Gatzi, Haukur Kristinsson, Beat Muller, Rene Muntwyler, Johannes P. Pachlatko, Hermann Rempfler, Rolf Schurter, Henry Szczepanski
Abstract: A particular class of novel nitro-substituted dyes has been found to act as effective, heat labile acutance dyes for photothermographic emulsions.
Type:
Grant
Filed:
June 27, 1980
Date of Patent:
February 23, 1982
Assignee:
Minnesota Mining and Manufacturing Company
Abstract: Tin-containing oxime derivatives of the formula ##STR1## wherein n is 0, 1 or 2,m is 0 or 1,Ar is an optionally substituted phenyl radical or an optionally substituted naphthyl radical, or when m is 0, Ar may also be an ester group,X is hydrogen, --CN, halogen, lower alkyl, lower alkanoyl, --COOH, a carboxylic acid ester radical, a carbamoyl radical andR.sub.8, R.sub.9 and R.sub.10, each independently of the other, are alkyl, aryl, aralkyl or C.sub.3 -C.sub.7 cycloalkyl, are suitable for protecting cultivated plants from the phytotoxic action of aggressive agrochemicals, in particular herbicides preferred are compounds of the above formula in whichAr is alkylphenyl, alkoxyphenyl, halophenyl, naphthyl or amido,X is cyano or a carboxylic acid ester radical, andR.sub.8, R.sub.9 and R.sub.10 are the same and are C.sub.1 -C.sub.4 alkyl, benzyl or phenyl.
Abstract: Sulphoalkyl quaternary salts of the formula ##STR1## wherein X is --O--, --Se--, --S--, --NR-- or --CR(R)--, R is hydrogen or alkyl, R.sub.1 is hydrogen, methyl or ethyl, R.sub.2 and R.sub.3 are each hydrogen or substituents or together represent the atoms necessary to complete an optionally substituted benzene ring, R.sub.4 is optionally substituted alkylene of 3 or 4 carbon atoms and n is 1 or 0, except that when n is 1, R.sub.1 cannot be hydrogen, are prepared by heating at a temperature above 80.degree. C. a heterocyclic base of the formula ##STR2## wherein X, R.sub.1, R.sub.2, R.sub.3 and n have the indicated meanings with a hydroxysulphonic acid of the formula HOR.sub.4 SO.sub.3 H.
Type:
Grant
Filed:
June 5, 1978
Date of Patent:
September 1, 1981
Assignee:
Ciba-Geigy AG
Inventors:
Rainer Kitzing, Geoffrey E. Ficken, Victor W. Dolden
Abstract: Photographic silver halide emulsions show increased speed and reduced latent image fading when a compound of the following structure is incorporated: ##STR1## wherein: X is --O--, --S--, --Se--, or ##STR2## Y represents the atoms completing a fused aromatic nucleus; Z is ##STR3## and R is hydrogen or lower alkyl of from 1 to 5 carbon atoms.
Type:
Grant
Filed:
August 16, 1982
Date of Patent:
January 3, 1984
Inventors:
Roger Lok, John P. Freeman, William N. Baum