Patent number: 6448293
Abstract: A compound of general formula (I), or pharmaceutically acceptable salts, solvates or polymorphs thereof; wherein; R1 and R2, which may be the same or different, are hydrogen, C1-C6alkyl, (CH2)m (C3-C6cycloalkyl) wherein m =0, 1, 2 or 3, or R1 and R2 together with the nitrogen to which they are attached form an azetidine ring; each R3 is independently CF3, OCF3, C1-4alkylthio or C1-C4alkoxy; n is 1, 2 or 3; and R4 and R5, which may be the same or different, are: A—X, wherein A =—CH=CH— or —(CH2)p— where p is 0, 1 or 2; X is hydrogen, F, Cl, Br, I, CONR6R7, SO2NR6R7, SO2NHC(=O)R6, OH, C1-4alkoxy, NR8SO2R9, NO2, NR6R11, CN, CO2R10, CHO, SR10, S(O)R9 or SO2R10; R6, R7, R8 and R10 which may be the same or different, are hydrogen or C1-6alkyl optionally substituted independently by one or more R12; R9 is C1-6 alkyl optionally substituted independently by one or more R12; R11 is hydrogen, C1-6 alkyl optionally substituted independently by one or more R12, C(O
Type:
Grant
Filed:
March 16, 2001
Date of Patent:
September 10, 2002
Assignee:
Pfizer Inc.
Inventors:
Mark David Andrews, David Hepworth, Donald Stuart Middleton, Alan Stobie
Publication number: 20020052395
Abstract: A compound of general formula (I), or pharmaceutically acceptable salts, solvates or polymorphs thereof; wherein; R1 and R2, which may be the same or different, are hydrogen, C1-C6alkyl, (CH2)m(C3-C6cycloalkyl) wherein m =0, 1, 2 or 3, or R1 and R2 together with the nitrogen to which they are attached form an azetidine ring; each R3 is independently CF3, OCF3, C1-4alkylthio or C1-C4alkoxy; n is 1, 2 or 3; and R4 and R5, which may be the same or different, are: A-X, wherein A =—CH=CH— or —(CH2)p— where p is 0, 1 or 2; X is hydrogen, F, Cl, Br, I, CONR6R7,SO2NR6R7, SO2NHC(=O)R6, OH, C1-4alkoxy, NR8SO2R9, NO2, NR6R11, CN, CO2R10, CHO, SR10, S(O)R9 or SO2R10 R6, R7, R and R10 which may be the same or different, are hydrogen or C1-6alkyl optionally substituted independently by one or more R12; R9 is C1-6 alkyl optionally substituted independently by one or more R12; R11 is hydrogen, C1-6 alkyl optionally substituted independently by one or more R12, C(O)R6, CO2R9
Type:
Application
Filed:
March 16, 2001
Publication date:
May 2, 2002
Inventors:
Mark David Andrews, David Hepworth, Donald Stuart Middleton, Alan Stobie
Patent number: 6352959
Abstract: Thiochromanoylpyrazolone derivatives of the formula I
where:
A is an unsubstituted or substituted, saturated or unsaturated alkyl chain;
R1 is cyano, thiocyanato, nitro, OR4, SR5, SOR6, S02R6, ONR6NR7, ON═CR6R8, NR9R10, P(O)R11R12, P(S)R11R12, COR, CO2R6, unsubstituted or substituted phenyl or heterocyclyl;
R2 is alkyl, haloalkyl, alkoxy or haloalkoxy;
R3 is hydrogen, alkyl or halogen;
X is oxygen, sulfur, S═O, S(═O)2, CR13R14, C═O or C═NR15;
m is 0, 1 or 2;
n is 0, 1, 2, 3 or 4;
R16 is substituted pyrazol-4-yl-carbonyl or substituted (4,5-dihydro-5-oxo-pyrazol-4-yl)methylidene;
and their agriculturally useful salts;
Processes for preparing the thiochromanoylpyrazolone derivatives, compositions comprising them, and the use of these derivatives or of the compositions comprising them for controlling undesirable plants are described.
Type:
Grant
Filed:
May 31, 2001
Date of Patent:
March 5, 2002
Assignee:
BASF Aktiengesellschaft
Inventors:
Klaus Langemann, Ernst Baumann, Wolfgang von Deyn, Steffen Kudis, Guido Mayer, Ulf Misslitz, Ulf Neidlein, Matthias Witschel, Norbert Götz, Martina Otten, Karl-Otto Westphalen, Helmut Walter