The Five-membered Hetero Ring Shares Ring Carbons With Two Benzene Rings (i.e., Carbazoles) Patents (Class 548/440)
  • Patent number: 7919500
    Abstract: The present invention is a DNA intercalating agent represented by the structure Y—Z—Y, wherein Y is an anti-tumor bis-carbazole and Z is a linear arrangement of multiple aromatic rings, containing at least two aromatic rings, or at least two alicyclic rings, wherein the rings are linked in a 1,4 or 1,3 manner. Methods of inhibiting cancer cells and treating subjects having cancer with these agents are also provided.
    Type: Grant
    Filed: July 8, 2009
    Date of Patent: April 5, 2011
    Assignee: Trustees of Dartmouth College
    Inventors: Gordon W. Gribble, Dmitry A. Androsov
  • Publication number: 20110074491
    Abstract: A photoelectric conversion device comprising an electrically conductive film, an organic photoelectric conversion film, and a transparent electrically conductive film, wherein the organic photoelectric conversion film contains a compound represented by the following formula (1) and an n-type organic semiconductor: wherein each of R1 and R2 independently represents a substituted aryl group, an unsubstituted aryl group, a substituted heteroaryl group or an unsubstituted heteroaryl group, each of R3 to R11 independently represents a hydrogen atom or a substituent provided that an acidic group is excluded, m represents 0 or 1, n represents an integer of 0 or more, R1 and R2, R3 and R4, R3 and R5, R5 and R6, R6 and R8, R7 and R8, R7 and R9, or R10 and R11 may be combined each other to form a ring, and when n is an integer of 2 or more, out of a plurality of R7's and R8's, a pair of R7's, a pair of R8's, or a pair of R7 and R8 may be combined each other to form a ring.
    Type: Application
    Filed: September 28, 2010
    Publication date: March 31, 2011
    Applicant: FUJIFILM CORPORATION
    Inventors: Katsuyuki YOFU, Kimiatsu NOMURA, Mitsumasa HAMANO, Tetsuro MITSUI
  • Patent number: 7915428
    Abstract: A photorefractive dendron compound, a photorefractive dendrimer compound and applications thereof, and more particularly, a photorefractive dendron compound, including a non-linear chromophore containing a tricyanopyrroline-based electron-withdrawing group and a carbazole derivative having excellent charge transport properties, a method of preparing the photorefractive dendrimer compound, a photorefractive device including the photorefractive dendrimer compound, and a method of manufacturing the photorefractive device. In the photorefractive dendrimer compound, dendron has the non-linear optical chromophore and carbazole introduced thereto to thus impart one molecule with both photoconductivity and non-linear optical properties, thereby solving conventional problems caused by poor compatibility between photoconductive material and chromophores in conventional photorefractive material.
    Type: Grant
    Filed: October 8, 2007
    Date of Patent: March 29, 2011
    Assignees: Samsung Electronics Co., Ltd., Seoul National University Industry Foundation, Korea University Industrial & Academic Collaboration Foundation
    Inventors: Dong Hoon Choi, Min Ju Cho, Kyung Moon Jung
  • Publication number: 20110050118
    Abstract: It is an object to provide a novel method for synthesizing an anthracene derivative with the small number of steps. It is another object to provide a novel anthracene derivative. It is further another object to provide a light-emitting element, a light-emitting device, and an electronic device, each using the anthracene derivative. A method for synthesizing an anthracene derivative represented by a general formula (1) is provided by coupling a 9-arylanthracene derivative having an active site at a 10-position with a 9-arylcarbazole derivative having an active site in an aryl group using metal, a metal compound, or a metal catalyst.
    Type: Application
    Filed: November 5, 2010
    Publication date: March 3, 2011
    Applicant: SEMICONDUCTOR ENERGY LABORATORY CO., LTD.
    Inventors: Masakazu EGAWA, Sachiko KAWAKAMI
  • Patent number: 7898171
    Abstract: The present invention provides a novel substance having an excellent color purity of blue, a light-emitting element and a light-emitting device using the novel substance. A stilbene derivative has a structure shown by the general formula (1). In the general formula (1), R1 is hydrogen, an alkyl group having 1 to 4 carbon atoms, or an aryl group having 6 to 25 carbon atoms. R2 is an alkyl group having 1 to 4 carbon atoms or an aryl group having 6 to 25 carbon atoms. Each of R3 to R5 is hydrogen or an alkyl group having 1 to 4 carbon atoms. Ar1 is an aryl group having 6 to 25 carbon atoms.
    Type: Grant
    Filed: January 9, 2009
    Date of Patent: March 1, 2011
    Assignee: Semiconductor Energy laboratory Co., Ltd.
    Inventors: Masakazu Egawa, Harue Nakashima, Sachiko Kawakami, Nobuharu Ohsawa, Satoshi Seo, Ryoji Nomura
  • Publication number: 20110046378
    Abstract: Disclosed here in are compounds and methods of diagnosing Alzheimer's Disease or a predisposition thereto in a mammal, the method comprising administering to the mammal a diagnostically effective amount of a radiolabeled compound, wherein the compound is selected from the group consisting of radiolabeled flavones, coumarins, carbazoles, quinolinones, chromenones, imidazoles and triazoles derivatives, allowing the compound to distribute into the brain tissue, and imaging the brain tissue, wherein an increase in binding of the compound to the brain tissue compared to a normal control level of binding indicates that the mammal is suffering from or is at risk of developing Alzheimer's Disease
    Type: Application
    Filed: February 17, 2009
    Publication date: February 24, 2011
    Applicant: SIEMENS MEDICAL SOLUTIONS USA, INC.
    Inventors: Hartmuth C. Kolb, Joseph C. Walsh, Qianwa Liang, Brian A. Duclos, Wei Zhang, Peter J.H. Scott, Kai Chen, Zhiyong Gao, Tieming Zhao, Vani P. Mocharla, Dhanalakshmi Kasi, Gang Chen, Eric Wang, Anjana Sinha, Chunfang Xia, Henry Clifton Padgett, Farhad Karimi
  • Publication number: 20110042654
    Abstract: Disclosed is an organic compound represented by the following Chemical Formula 1 that easily dissolves in an organic solvent, and that is applicable as a host material of an emission layer of an organic photoelectric device since it emits fluorescence and phosphorescence at a red wavelength through a blue wavelength.
    Type: Application
    Filed: March 12, 2010
    Publication date: February 24, 2011
    Inventors: Sung-Hyun Jung, Hyung-Sun Kim, Ho-Jae Lee, Eun-Sun Yu, Mi-Young Chae
  • Publication number: 20110037027
    Abstract: The present invention relates to fluorine derivatives and organic electronic devices in which said compounds are used as a matrix material in the emitting layer and/or as a hole transport material, and/or as an electron blocking or exciton blocking material, and/or as an electron transport material.
    Type: Application
    Filed: March 11, 2009
    Publication date: February 17, 2011
    Inventors: Philipp Stoessel, Holger Heil, Dominik Joosten, Christof Pfumm, Anja Gerhard
  • Patent number: 7887932
    Abstract: An organic light-emitting device including a first electrode, a second electrode, and an organic layer interposed between the first electrode and the second electrode. The organic layer includes at least one organosiloxane compound selected from organosiloxane compounds represented by An organic light-emitting device using the organosiloxane compound has a low operating voltage, high color purity, and high efficiency.
    Type: Grant
    Filed: June 7, 2006
    Date of Patent: February 15, 2011
    Assignee: Samsung Mobile Display Co., Ltd.
    Inventors: Yi-Yeol Lyu, Jong-Jin Park, Byoung-Ki Choi, Myeong-Suk Kim, Sung-Hun Lee, Lyong-Sun Pu, Ok-Kyung Cho, Young-Mok Son, O-Hyun Kwon, Young-Hun Byun, Das Rupasree Ragini
  • Publication number: 20110031484
    Abstract: A condensed-cyclic compound represented by Formula 1 and an organic light emitting diode including the same:
    Type: Application
    Filed: August 9, 2010
    Publication date: February 10, 2011
    Applicant: Samsung Mobile Display Co., Ltd.
    Inventors: Kwan-Hee Lee, Mi-Kyung Kim, Seung-Gak Yang
  • Patent number: 7879900
    Abstract: A compound of formula (I), in which R1, R2, R3, R4, R5, R6, X and Y have the meanings indicated in the description, and the pharmaceutically acceptable salts thereof. A pharmaceutical composition containing a compound of formula (I) or a pharmaceutically acceptable salt thereof. A method for preparing the abovementioned compound of formula (I) and the pharmaceutically acceptable salts thereof.
    Type: Grant
    Filed: July 25, 2006
    Date of Patent: February 1, 2011
    Assignee: Aziende Chimiche Riunite Angelini Francesco A.C.R.A.F. S.p.A.
    Inventors: Maria Alessandra Alisi, Patrizia Dragone, Guido Furlotti, Nicola Cazzolla, Vincenzo Russo, Giorgina Mangano, Isabella Coletta, Lorenzo Polenzani
  • Patent number: 7867631
    Abstract: A fluorine-containing compound is represented by Formula 1 below: wherein R1a, R1b, R2a, and R2b are each independently a hydrogen atom, a substituted or unsubstituted C1-C30 alkyl group, a substituted or unsubstituted C1-C30 alkoxy group, a substituted or unsubstituted C6-C30 aryl group, a substituted or unsubstituted C6-C30 aryloxy group, a substituted or unsubstituted C4-C30 heteroaryl group, a substituted or unsubstituted C6-C30 condensed polycyclic group, a hydroxy group, halogen, a cyano group, or a substituted or unsubstituted amino group, and adjacent groups selected from R1a, R1b, R2a, and R2b may join together to form a saturated or unsaturated carbon ring; n and m are each independently an integer of 0 to 5; Ar1a and Ar1b are each independently a C6-C30 aryl group which is unsubstituted or substituted by at least one fluorine or a C4-C30 heteroaryl group which is unsubstituted or substituted by at least one fluorine; and Ar2 is a substituted or unsubstituted C6-C30 aryl group or a substituted
    Type: Grant
    Filed: October 26, 2007
    Date of Patent: January 11, 2011
    Assignee: Samsung Mobile Display Co., Ltd.
    Inventors: Young-Kook Kim, Seok-Hwan Hwang, Yoon-Hyun Kwak, Hye-Lim Lee
  • Publication number: 20110004003
    Abstract: A novel high-performance material is provided. A certain aspect of the present invention lies in a 2,3-bis(N,N-bis(p-anisyl)4-aminophenylethynyl)dimethylfumarate producing method, characterized by illuminating light onto 2,3-bis(N,N-bis(p-anisyl)4-aminophenylethynyl)dimethylmaleate. Also, a further certain aspect of the present invention lies in a 2,3-bis(N,N-bis(p-anisyl)4-aminophenylethynyl)dimethylmaleate producing method, characterized by illuminating light onto 2,3-bis(N,N-bis(p-anisyl)4-aminophenylethynyl)dimethylfumarate. According to this constitution, there can be obtained a high-performance material by a simple technique.
    Type: Application
    Filed: August 1, 2008
    Publication date: January 6, 2011
    Applicant: The University of Tokyo
    Inventors: Hiroshi Nishihara, Ryota Sakamoto
  • Publication number: 20100327269
    Abstract: Disclosed herein are compounds represented by Formula 1. Compositions and light-emitting devices related thereto are also disclosed.
    Type: Application
    Filed: June 29, 2010
    Publication date: December 30, 2010
    Inventors: Shijun Zheng, Jensen Cayas, Sheng Li, Amane Mochizuchi, Hyunsik Chae
  • Patent number: 7854999
    Abstract: Provided are a cyclopentaphenanthrene-based compound and an organoelectroluminescent device employing the same. The cyclopentaphenanthrene-based compound is easy to prepare and excellent in solubility, color purity, color stability, and thermal stability. The cyclopentaphenanthrene-based compound is useful as a material for forming an organic layer, in particular, an emitting layer, in an organoelectroluminescent device, and as an organic dye or an electronic material such as a nonlinear optical material.
    Type: Grant
    Filed: July 18, 2007
    Date of Patent: December 21, 2010
    Assignee: Samsung Mobile Display Co., Ltd.
    Inventors: Sang-Hoon Park, Yu-Jin Kim, Jhun-Mo Son
  • Publication number: 20100292488
    Abstract: Organic dyes and photoelectric conversion devices are provided. The Organic dye has the structure represented by formula (I), wherein, n is an integral of 2-11; the plurality of X is independent and elected from the group consisting of and combinations thereof; R, R1, and R2 comprise hydrogen, halogen, C1-18 alkyl group, C1-18 alkoxy group, C3-18 heteroalkyl group, C3-20 aryl group, C3-20 heteroaryl group, C3-20 cycloaliphatic group or C3-20 cycloalkyl group, or R1 is connected to R2 to form a ring having 5-14 members; R3 comprise hydrogen, halogen, nitro group, amino group, C1-18 alkyl group, C1-18 alkoxy group, C1-18 sulfanyl group, C3-18 heteroalkyl group, C3-20 aryl group, C3-20 heteroaryl group, C3-20 cycloaliphatic group or C3-20 cycloalkyl group; and Z is hydrogen, alkali metal, or quaternary ammonium salt.
    Type: Application
    Filed: December 31, 2009
    Publication date: November 18, 2010
    Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
    Inventors: Yung-Liang Tung, Jia-Yin Wu, Jen-An Chen, Hsin-Yi Hsu, Chun-Guey Wu, Min-Fong Jhong, Song-Yeu Tsai
  • Patent number: 7829204
    Abstract: A material for organic electroluminescence device with specific structure having poor symmetry. An an organic electroluminescence device comprising a cathode, an anode and an organic thin film layer which is sandwiched between the cathode and the anode and comprises at least one layer, wherein at least one layer in the organic thin film layer contains a material for the organic electroluminescence device described above. An organic electroluminescence device with excellent efficiency of light emission, without pixel defects and which is superior in heat resistance is obtained.
    Type: Grant
    Filed: December 13, 2004
    Date of Patent: November 9, 2010
    Assignee: Idemitsu Kosan Co., Ltd.
    Inventors: Toshihiro Iwakuma, Seiji Tomita, Mitsunori Ito
  • Publication number: 20100277063
    Abstract: A fluorene-based derivative having a specific structure and an organic electro-luminescence device in which an organic thin film layer comprising a single layer or plural layers including at least a light emitting layer is sandwiched between a cathode and an anode, wherein at least one layer of the organic thin film layers described above comprises the above fluorene-based derivative having a specific structure in the form of a single component or a mixed component. The organic electroluminescence device has a high luminous efficiency, and the fluorene-based derivative materializes the same.
    Type: Application
    Filed: July 19, 2010
    Publication date: November 4, 2010
    Applicant: Idemitsu Kosan Co., Ltd.
    Inventors: Mitsunori ITO, Hiroshi Yamamoto, Satoshi Hachiya, Hisayuki Kawamura
  • Publication number: 20100276673
    Abstract: Disclosed is an organic compound that easily dissolves in an organic solvent, and that is applicable as a host material of an emission layer of an organic photoelectric device since it emits fluorescence and phosphorescence at a red wavelength through a blue wavelength. The organic compound according to one embodiment of the present invention is represented by Chemical Formula 1. In the above Chemical Formula 1, X1 to X24, Ar1 to Ar3, and Ar? to Ar??, and Chemical Formulae 2 to 5, are as described in the specification. The organic compound easily dissolves in an organic solvent, and is applicable as a host material of an emission layer of an organic photoelectric device since it emits fluorescence and phosphorescence at a red wavelength through a blue wavelength.
    Type: Application
    Filed: March 12, 2010
    Publication date: November 4, 2010
    Inventors: Sung-Hyun Jung, Hyung-Sun Kim, Ho-Jae Lee, Eun-Sun Yu, Mi-Young Chae
  • Patent number: 7816021
    Abstract: Provided are a carbazole-based compound represented by Formula 1 below and an organic light-emitting device including an organic layer including the carbazole-based compound: wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, R12, R13, and R14 are as defined in the specification. The carbazole-based compound has good electrical characteristics and charge transport capability, and thus, is useful as a hole injection material, a hole transport material, and/or an emitting material for fluorescent or phosphorescent devices capable of producing light of a full spectrum of colors, including red, green, blue, and white, thereby making it possible to produce an organic light-emitting device with high efficiency, a low driving voltage, and high brightness.
    Type: Grant
    Filed: October 29, 2007
    Date of Patent: October 19, 2010
    Assignee: Samsung Mobile Display Co., Ltd.
    Inventors: Young-Kook Kim, Seok-Hwan Hwang, Yoon-Hyun Kwak
  • Publication number: 20100244008
    Abstract: The present invention provides a novel compound that is capable of largely improving lifespan, efficiency, electrochemical stability and thermal stability of the organic light emitting device, and an organic light emitting device in which the compound is included in an organic compound layer.
    Type: Application
    Filed: November 7, 2008
    Publication date: September 30, 2010
    Inventors: Jae- Chol Lee, Kong-Kyeom Kim, Sung-Kil Hong, Tae-Yoon Park
  • Patent number: 7795801
    Abstract: An organic electroluminescent element comprising a light emission layer and a hole blocking layer adjacent to the light emission layer, wherein, (i) the light emission layer contains a compound having a specified partial structure and having a molecular weight of not more than 1700; and (ii) the hole blocking layer contains a derivative selected from the group consisting of a styryl derivative, a boron derivative and a carboline derivative.
    Type: Grant
    Filed: September 21, 2004
    Date of Patent: September 14, 2010
    Assignee: Konica Minolta Holdings, Inc.
    Inventors: Noriko Ueda, Taketoshi Yamada, Hiroshi Kita, Mitsuhiro Fukuda
  • Patent number: 7790892
    Abstract: A novel aromatic compound having an anthracene skeleton structure and an asymmetric molecular structure; and an organic electroluminescence device which comprises a cathode, an anode and an organic thin film layer comprising at least one layer containing a light emitting layer and sandwiched between the cathode and the anode in which at least one layer in the organic thin film layer contains the above novel aromatic compound singly or as a component of a mixture. The organic electroluminescence device exhibits a great luminance of emitted light, a great efficiency of light emission and a high purity of color, emits bluish light, is excellent in stability at high temperatures and has a long life. The organic electroluminescence device can be provided by utilizing the novel aromatic compound.
    Type: Grant
    Filed: April 17, 2003
    Date of Patent: September 7, 2010
    Assignee: Idemitsu Kosan Co., Ltd.
    Inventors: Hidetsugu Ikeda, Masahide Matsuura, Masakazu Funahashi, Chishio Hosokawa
  • Publication number: 20100187978
    Abstract: The present invention relates to a material for an organic electro-optical device and an organic electro-optical device including the same. More particularly, the present invention relates to a material having thermal stability of a glass transition temperature of 120° C. or more and a thermal decomposition temperature of 450° C. or more, and being capable of providing an organic electro-optical device having high efficiency and a long life-span due to less crystallization and improved amorphous properties in a material for an organic electro-optical device. The material for an organic electro-optical device can be used singularly or as a host material in combination with a dopant, and includes an asymmetric fluorene derivative compound. An organic electro-optical device including the material for an organic electro-optical device is also provided.
    Type: Application
    Filed: May 28, 2008
    Publication date: July 29, 2010
    Applicant: CHEIL INDUSTRIES INC.
    Inventors: Eun Sun Yu, Nam Soo Kim, Young Hoon Kim, Mi Young Chae
  • Patent number: 7763691
    Abstract: Norbornene monomers with fluorene group and polymer material thereof are disclosed. The norbornene monomers with fluorene group are prepared by Diels-Alder reation. The Norbornene monomers containing fluorene groups are highly active for ring-opening-metathesis polymerization (ROMP), and the molecular weight and PDI value of the obtained polymers are controllable.
    Type: Grant
    Filed: October 5, 2007
    Date of Patent: July 27, 2010
    Assignee: National Taiwan University of Science & Technology
    Inventor: Der-Jang Liaw
  • Patent number: 7763645
    Abstract: Disclosed herein is crystalline carvedilol dihydrogen phosphate monohydrate having high aqueous solubility and the process for preparation thereof. The invention further discloses methods for treating hypertension, congestive heart failure and angina in a mammal, using pharmaceutical compositions comprising the compound of invention.
    Type: Grant
    Filed: October 8, 2008
    Date of Patent: July 27, 2010
    Assignee: Wanbury Limited
    Inventors: Shankar Sanganabhatla, Sunanda Manoj, Ramanarasimha Moorthy Koduru
  • Publication number: 20100181900
    Abstract: A carbazole compound represented by Formula 1: wherein X1, X2 and X3 are each independently selected from the group consisting of a hydrogen atom, a substituted or unsubstituted C1-C20 alkyl group, a substituted or unsubstituted C1-C20 alkoxy group, a substituted or unsubstituted C6-C30 aryl group, a substituted or unsubstituted C6-C30 arylalkyl group, a substituted or unsubstituted C2-C30 heteroaryl group, a substituted or unsubstituted C3-C20 cycloalkyl group and a substituted or unsubstituted C5-C30 heterocycloalkyl group; and l, m and n are each independently an integer from 0 to 5.
    Type: Application
    Filed: October 27, 2009
    Publication date: July 22, 2010
    Applicant: SAMSUNG ELECTRONICS CO., LTD
    Inventors: Yi-yeol Lyu, Kook-heon Char, Chang-hee Lee, Jeong-hun Kwak
  • Publication number: 20100184942
    Abstract: Compounds (including polymers) for use in hybrid host materials which can be used in electroluminescent devices. The compounds comprise at least one electron-transporting moiety and at least one hole-transporting moiety which are joined by a flexible linker. Hybrid host materials comprising the compounds exhibit stability against phase separation, elevated glass transition temperature, morphological stability against crystallization, and isolation of the electron transporting moiety and hole transporting moiety ?-systems.
    Type: Application
    Filed: January 22, 2010
    Publication date: July 22, 2010
    Inventors: Shaw H. Chen, Lichang Zeng, Thomas Yung-Hsin Lee
  • Patent number: 7758972
    Abstract: An object is to provide a novel substance which exhibits blue light emission with excellent color purity, and to provide a light emitting element and a light emitting device using the novel substance. A stilbene derivative represented by the general formula (G1) is provided. Note that in the general formula (G1), each of A1 and B1 represents any one of structures represented by the following general formulae (G1-1) to (G1-4). In addition, in each of the general formulae (G1-1) to (G1-4), each of R1 to R24 represents any one of hydrogen and an alkyl group having 1 to 4 carbon atoms. Such a stilbene derivative can exhibit blue light emission with excellent color purity.
    Type: Grant
    Filed: September 17, 2007
    Date of Patent: July 20, 2010
    Assignee: Semiconductor Energy Laboratory Co., Ltd.
    Inventors: Masakazu Egawa, Sachiko Kawakami, Nobuharu Ohsawa
  • Publication number: 20100172960
    Abstract: The novel positively charged pro-drugs of NSAIAs in the general formulas (1, 2a, 2b, 2c, or 2d) “Structure 1, 2a, 2b, 2c, or 2d” were designed and synthesized. The compounds of the general formulas (1, 2a, 2b, 2c, or 2d) “Structure 1, 2a, 2b, 2c, or 2d” indicated above can be prepared from metal salts, organic base salts, or immobilized base salts of NSAIAs with suitable halide compounds. The positively charged amino groups in the pro-drugs in this invention largely increase the solubility of the drugs in water and will bond to the negative charge on the phosphate head group of membrane. Thus, the local concentration of the outside of the membrane or skin will be very high and will facilitate the passage of these pro-drugs from a region of high concentration to a region of low concentration. This bonding will disturb the membrane a little bit and may make some room for the lipophilic portion of the pro-drug.
    Type: Application
    Filed: June 4, 2007
    Publication date: July 8, 2010
    Inventors: Chongxi Yu, Lina Xu
  • Publication number: 20100174095
    Abstract: The present invention provides: an organic compound increasing an open circuit voltage, and showing high photoelectric conversion efficiency; a semiconductor film electrode employing the organic compound as a dye; a photoelectric conversion element employing the semiconductor film electrode; and a photoelectrochemical solar cell employing the photoelectric conversion element.
    Type: Application
    Filed: March 27, 2007
    Publication date: July 8, 2010
    Applicant: NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY
    Inventors: Nagatoshi Koumura, Koujirou Hara
  • Patent number: 7750036
    Abstract: The present invention relates to a salt of carvedilol and/or corresponding solvates thereof, compositions containing such carvedilol and/or corresponding solvates thereof, and/or methods of using the aforementioned compound(s) in the treatment of certain disease states in mammals, in particular man. The present invention further relates to carvedilol phosphate salts, and/or solvates thereof, which include a novel crystalline form of carvedilol dihydrogen phosphate (i.e., which is the dihydrogen phosphate salt of 1-(carbazol-4-yloxy-3-[[2-(o-methoxyphenoxy)ethyl]amino]-2-propanol) and/or carvedilol hydrogen phosphate, etc.) and/or other corresponding solvates thereof, compositions containing these carvedilol phosphate salts and/or solvates, and methods of using the aforementioned salts and/or solvates to treat hypertension, congestive heart failure and angina, etc.
    Type: Grant
    Filed: November 24, 2004
    Date of Patent: July 6, 2010
    Assignee: SB Pharmco Puerto Rico Inc.
    Inventors: Christopher S. Brook, Pingyun Y. Chen, Wei Chen, Qunying Dai, Philip C. Dell'Orco, Clifford S. Labaw, Ann Marie Diederich, Choon K. Oh, Claire Hisler, David H. Igo, Lee M. Katrincic, Li-Jen Ping, Paul G. Spoors, Jun Wang, Christopher Werner
  • Patent number: 7745988
    Abstract: A 3,6-diphenylcarbazole compound, which has a specific formula and realizes an organic electroluminescent device having high durability and high luminous efficiency. An electroluminescent device which includes an anode; a cathode which faces the anode; and at least one layer including a luminescent layer, optionally a hole transporting layer and an electron transporting layer, which is located between the anode and the cathode, wherein the at least one layer includes the 3,6-diphenylcarbazole compound.
    Type: Grant
    Filed: September 3, 2004
    Date of Patent: June 29, 2010
    Assignee: Ricoh Company, Limited
    Inventors: Masaomi Sasaki, Masafumi Torii, Toshiya Sagisaka, Takashi Okada, Shinichi Kawamura, Chihaya Adachi, Yuuichiroh Kawamura, Kenji Muneuchi
  • Patent number: 7737627
    Abstract: The present invention relates to an organic electroluminescent (OEL) compound that comprises at least one fluorene derivative and at least one carbazole derivative. The compound has good electrical properties, light emitting properties and charge transport ability, and thus is suitable as a host material suitable for fluorescent and phosphorescent dopants of all colors including red, green, blue, white, etc., and as a charge transport material. An OEL display device that uses an organic layer that includes the OEL compound has a high efficiency, a low voltage, a high luminance, and a long lifespan because it has superior current density.
    Type: Grant
    Filed: April 4, 2005
    Date of Patent: June 15, 2010
    Assignee: Samsung Mobile Display Co., Ltd.
    Inventors: Seok-Hwan Hwang, Seok-Jong Lee, Young-Kook Kim, Seung-Gak Yang, Hee-Yeon Kim
  • Publication number: 20100145067
    Abstract: The invention discloses a novel carbazole derivative which has at least two carbazole structures in the molecule, can form a stable amorphous film by itself at normal temperature or higher, has a high glass transition temperature, and can be suitably used as an organo-electronic functional material. The following compound having the formula is mentioned as a representative example.
    Type: Application
    Filed: November 9, 2007
    Publication date: June 10, 2010
    Inventors: Masami Yokota, Tomoyuki Tusbaki
  • Publication number: 20100140603
    Abstract: A blue light emitting compound is provided. The blue light emitting compound has a structure of the following Chemical Formula 1: wherein A1, A2, and A3 are each independently selected from the group consisting of hydrogen, a substituted or unsubstituted aromatic group, a hetero ring group, and an aliphatic group.
    Type: Application
    Filed: December 3, 2009
    Publication date: June 10, 2010
    Inventors: Hyuncheol Jeong, Chungun Park
  • Publication number: 20100137599
    Abstract: The present invention relates to a process for the preparation of 1,4-butanediol mononitrate as intermediate for large scale preparation of high purity nitrooxybutyl ester of pharmaceutically active compounds.
    Type: Application
    Filed: June 18, 2008
    Publication date: June 3, 2010
    Applicant: NICOX S.A.
    Inventors: Achim Hack, Gunter Weingarner, Matthias Kramer
  • Patent number: 7727690
    Abstract: Disclosed are a monomer of iridium complex having a fluoro group as a functional group, a monomer of carbazole derivative having a hydroxy group as the functional group, and a copolymer containing the monomers in its main chain. The iridium complex used as a phosphorescent material and the carbazole derivative having an excellent hole transporting capability are synthesized as the monomer to form the copolymer. The content of iridium complex is easily controlled, and the carbazole derivative and iridium complex are contained in the main chain during the copolymer formation, thereby capable of manufacturing a light emitting device with higher heat resistance and chemical stability.
    Type: Grant
    Filed: November 16, 2007
    Date of Patent: June 1, 2010
    Assignee: Gwangju Institute of Science and Technology
    Inventors: Jae-Suk Lee, Nam-Goo Kang, Hyo-Jin Jeon
  • Publication number: 20100130579
    Abstract: The present invention relates to methods of inducing expression of an epigenetically silenced gene, RASSF1A, in cells, particularly human cells, such as cancer cells. It also relates to methods of treating an individual, prophylactically or therapeutically, for cancer in which RASSF1A is epigenetically silenced.
    Type: Application
    Filed: October 23, 2007
    Publication date: May 27, 2010
    Applicant: Georgetown University
    Inventors: Partha Banerjee, Shankar Jagadeesh, Mikell Paige, Kathryn Ditmer, Milton L. Brown
  • Publication number: 20100130750
    Abstract: The present invention discloses a benzocarbazole-intercalated layered double hydroxides (LDHs) composite luminescent material and its preparation method. The detailed procedure comprises preparing divalent and trivalent metal cation solution A and glycol solution B of sodium 2-hydroxy benzo[a]carbazole-3-carboxylate, mixing the solutions A and B to obtain solution C, slowly adding the prepared NaOH solution dropwise into the solution C, regulating pH of the resultant after dropwise addition to obtain slurry D, allowing the slurry D to react under water bath or microwave temperature-controlled heating condition, centrifuging and washing the obtained product, and drying in vacuum to obtain 2-hydroxy benzo[a]carbazole-3-carboxylate anion intercalated LDHs composite material.
    Type: Application
    Filed: July 7, 2009
    Publication date: May 27, 2010
    Inventors: Dongpeng Yan, Jun Lu, Min Wei, Xue Duan
  • Patent number: 7714145
    Abstract: The present invention discloses synthesis of 2,2?-disubstituted 9,9?-spirobifluorene-based triaryldiamine. First, 2,2?-diamino-9,9?-spirobifluorene, a Pd-catalyst as auxiliary and aryl halide BX are provided, wherein X is selected from the group consisting of: Cl, Br and I, B comprises one of the following group: aryl moiety, hetero cycle, multiple fused ring, multiple fused ring with hetero atom(s). Next, a substitution reaction is performed to react the 2,2?-diamino-9,9?-spirobifluorene with the aryl halide BX to produce the 2,2?-disubstituted 9,9?-spirobifluorene-based triaryldiamines. In addition, the present invention discloses organic light emitting devices comprising hole transporting material comprising 2,2?-bis(N,N-disubstituted amino)-9,9?-spirobifluorenes.
    Type: Grant
    Filed: May 15, 2007
    Date of Patent: May 11, 2010
    Inventors: Ming-Han Tsai, Hao-Wu Lin, Hai-Ching Su, Chung-Chih Wu, Fu-Chuan Fang, Yuan-Li Liao, Ken-Tsung Wong, Chih-I Wu, Chi-Yen Lin, Wen-Yi Hung, Tei-Hung Hou, Wei-Jiun Chen
  • Publication number: 20100112479
    Abstract: A photopolymerization initiator is provided. The photopolymerization initiator contains at least one unsaturated double bond and at least one oxime ester group in the molecule. The photopolymerization initiator comprises a compound represented by Formula 1 or 2: wherein R1 and R2 are each independently —CH3, —C2H5, —C3H7 or —C6H5; wherein R3, R4 and R5 are each independently —CH3, —C2H5, —C3H7 or —C6H5. Further provided is a photosensitive resin composition comprising the photopolymerization initiator. The use of the photosensitive resin composition in photolithography reduces the formation of volatile residue during post-development baking.
    Type: Application
    Filed: October 30, 2009
    Publication date: May 6, 2010
    Inventors: Keon Woo Lee, Raisa Kharbash, Chang Ho Cho, Sung Hyun Kim, Sang Kyu Kwak, Dong Kung Oh, Chang Soon Lee
  • Patent number: 7705163
    Abstract: A process for the preparation of carvedilol of formula (I) (I) either in enantiomeric substantially pure form, or as an enantiomeric mixture, optionally as a pharmaceutically acceptable salt thereof, which process comprises reacting 2,3-eopxypropoxy carbazole of formula (II) (II) or the R or S enantiomer thereof, with N-[2-(2-methoxy-phenoxy)ethyl]-benzylamine of formula (V) (V) to yield benzyl carvedilol of formula (VI) (VI) which is debenzylated by catalytic hydrogenation to yield carvedilol of formula (I), either in enantiomeric substantially pure form, or as an enantiomeric mixture, and if desired reacting the thus formed carvedilol of formula (I) with an inorganic or organic acid to yield a pharmaceutically acceptable salt thereof, and/or, if desired, separating the enantiomers. The above process is characterised in that reaction of said 2,3-epoxypropoxy carbazole of formula (II) with said N-[2-(2-methoxy-phenoxy)ethyl]-benzylamine of formula (V) is carried out in water as the reaction medium.
    Type: Grant
    Filed: May 19, 2005
    Date of Patent: April 27, 2010
    Assignee: Cipla Limited
    Inventors: Rajendra Narayanrao Kankan, Dharmaraj Ramachandra Rao
  • Publication number: 20100098634
    Abstract: Provided herein are compounds and compositions which comprise the formulae as disclosed herein, wherein the compound is an amyloid binding compound. An amyloid binding compound according to the invention may be administered to a patient in amounts suitable for in vivo imaging of amyloid deposits, and distinguish between neurological tissue with amyloid deposits and normal neurological tissue. Amyloid probes of the invention may be used to detect and quantitate amyloid deposits in diseases including, for example, Down's syndrome, familial Alzheimer's Disease. In another embodiment, the compounds may be used in the treatment or prophylaxis of neurodegenerative disorders. Also provided herein are methods of allowing the compound to distribute into the brain tissue, and imaging the brain tissue, wherein an increase in binding of the compound to the brain tissue compared to a normal control level of binding indicates that the mammal is suffering from or is at risk of developing a neurodegenerative disease.
    Type: Application
    Filed: July 24, 2009
    Publication date: April 22, 2010
    Inventors: Hartmuth C. Kolb, Joseph C. Walsh, Wei Zhang, Umesh B. Gangadharmath, Dhanalakshmi Kasi, Kai Chen, Anjana Sinha, Eric Wang, Gang Chen, Peter J.H. Scott, Henry Clifton Padgett, Qianwa Liang, Zhiyong Gao, Tieming Zhao, Chunfang Xia
  • Publication number: 20100099890
    Abstract: An anthracene derivative is disclosed, and a light-emitting element, a light-emitting device, an electronic device, and a lighting device using the anthracene derivatives are demonstrated. The structure of the anthracene derivative is described in detail in the specification. The use of the anthracene derivative enables the production of a blue emissive light-emitting element having high emission efficiency, excellent purity of emission color, and a long lifetime, which contributes to the production of a high-performance light-emitting device, electronic device, and lighting device.
    Type: Application
    Filed: October 8, 2009
    Publication date: April 22, 2010
    Applicant: SEMICONDUCTOR ENERGY LABORATORY CO., LTD.
    Inventors: Kaori Ogita, Sachiko Kawakami, Tsunenori Suzuki, Satoshi Seo
  • Publication number: 20100089439
    Abstract: Disclosed is a compound which is an organic semiconductor material having excellent charge transport property. Specifically, disclosed is a compound represented by the following formula (1). (In the formula (1), R1-R4 independently represent a hydrogen atom, or a group selected from the group consisting of alkyl groups having 1-18 carbon atoms and groups represented by the following formula (2): R7?O—R8?a??(2) (2) (wherein R7 represents an alkyl group having 1-18 carbon atoms; R8 represents an alkylene group having 1-20 carbon atoms; a represents an integer of 1-5, and when a is 2 or more, R8's may be the same as or different from each other), and at least one of R1-R4 represents a group represented by the formula (2); R5 and R6 independently represent an alkyl group having 1-18 carbon atoms; and m and n independently represent an integer of 0-4.
    Type: Application
    Filed: February 26, 2007
    Publication date: April 15, 2010
    Inventors: Yasunori Uetani, Jun Fujiwara, Hirotoshi Nakanishi
  • Patent number: 7696348
    Abstract: It is an object to provide a novel bipolar organic compound. In particular, it is an object to provide a bipolar organic compound excellent in thermal stability. Further, it is another object to provide a bipolar organic compound which is electrochemically stable. A quinoxaline derivative represented by a general formula (1) is provided. Further, since the quinoxaline derivative represented by the general formula (1) is bipolar, the use of the quinoxaline derivative of the present invention allows fabrication of a light-emitting element and a light-emitting device with a low driving voltage and low power consumption. Furthermore, a light-emitting element with high luminous efficiency can be obtained.
    Type: Grant
    Filed: March 19, 2007
    Date of Patent: April 13, 2010
    Assignee: Semiconductor Energy Laboratories Co., Ltd.
    Inventors: Masakazu Egawa, Sachiko Kawakami, Harue Nakashima, Nobuharu Ohsawa, Satoshi Seo, Ryoji Nomura
  • Patent number: 7696257
    Abstract: An oxime ester compound represented below is useful as a photopolymerization initiator. A photopolymerization initiator including this as an active constituent has high sensitivity and causes no concern about coloration or contamination. (X represents a halogen atom or alkyl group. R1, R2, and R3 each independently represent R, OR, COR, SR, CONRR?, or CN, wherein R and R? each represent an alkyl group, an aryl group, an aralkyl group, or a heterocyclic group; these groups may be substituted with (a) halogen atom(s) and/or (a) heterocyclic group(s); the alkylene moiety in the alkyl or aralkyl group may be interrupted by (an) unsaturated bond(s), (an) ether bond(s), (a) thioether bond(s), or (an) ester bond(s); and R and R? may form a ring. Y1 represents an oxygen, sulfur, or selenium atom; A represents a heterocyclic group; m represents an integer 0-4; p represents an integer 0-5; and q represents 0 or 1.
    Type: Grant
    Filed: August 3, 2005
    Date of Patent: April 13, 2010
    Assignee: Adeka Corporation
    Inventors: Mitsuo Akutsu, Daisuke Sawamoto, Yasunori Kozaki, Toshihiko Murai
  • Patent number: 7691491
    Abstract: Novel monoaminofluorene compounds are provided, and organic light-emitting devices which exhibit good luminescence hue of extremely high purity and have optical output with high luminescence efficiency, high luminance and longer operating life are provided using the compounds.
    Type: Grant
    Filed: August 12, 2003
    Date of Patent: April 6, 2010
    Assignee: Canon Kabushiki Kaisha
    Inventors: Akihito Saitoh, Mizuho Hiraoka, Koichi Suzuki, Akihiro Senoo, Hiroshi Tanabe, Naoki Yamada, Chika Negishi
  • Publication number: 20100072887
    Abstract: The present invention provides organoselenium compounds comprising dibenzoselenophene, benzo[b]selenophene or benzo[c]selenophene and their uses in organic light emitting devices.
    Type: Application
    Filed: September 24, 2009
    Publication date: March 25, 2010
    Inventors: Raymond KWONG, Bin MA, Chuanjun XIA, Chun LIN