Abstract: Compounds of the formula I ##STR1## in which R.sup.1 to R.sup.8 independently of one another are H and at least one of R.sup.1 and R.sup.8 is a substituent belonging to the group --F, --Si(C.sub.1 -C.sub.4 alkyl).sub.3 or --COOR.sup.10 ; or each pair of adjacent radicals of R.sup.1 to R.sup.8 is --CO--O--CO--; or at least one of R.sup.1 to R.sup.8 is C.sub.1 -C.sub.20 alkyl-(X).sub.p --, C.sub.2 -C.sub.20 alkenyl-(X).sub.p --, C.sub.2 -C.sub.20 -alkynyl-(X).sub.p --, C.sub.3 -C.sub.8 cycloalkyl-(X).sub.p --, (C.sub.1 -C.sub.12 alkyl-C.sub.3 -C.sub.8 cycloalkyl-(X).sub.p --, C.sub.3 -C.sub.8 -cycloalkyl-CH.sub.2 --(X).sub.p --, C.sub.1 -C.sub.12 alkyl-C.sub.3 -C.sub.8 cycloalkyl-CH.sub.2 --(X).sub.p --, C.sub.6 -C.sub.10 aryl-X--, C.sub.7 -C.sub.20 alkaryl-X--, C.sub.7 -C.sub.12 aralkyl-(X).sub.p -- or C.sub.8 -C.sub.20 -alkaralkyl-(X).sub.p -- or --Y-- (C.sub.m H.sub.2m --O)--.sub.n R.sup.10 each of which is unsubstituted or substituted by --F, --OH, --CN, C.sub.1 -C.sub.12 alkoxy, C.sub.1 -C.sub.

Abstract: Radical cation salts having the composition of formula I ##STR1## wherein x has a value from -0.1 to +0.2. These radical cation salts crystallize in needle form and are electric conductors. They can be incorporated in polymers to form conductive networks of crystal needles in a polymer matrix. The polymers can be used for making antistatically treated mouldings or electrodes.

Abstract: A process for the preparation of peri-dichalcogeno polycyclic aromatic compounds by preparing in a first step, in an amidic solvent, an alkali metal sulfide, selenide or telluride which, in a second step, is reacted with a peri-halogeno aromatic compound, which process comprises reacting in said first step an alkali metal base with elemental sulfur, selenium or tellurium at elevated temperature.

Abstract: Imidate derivatives of sulfamates having the following formula (I): ##STR1## wherein R.sub.1, R.sub.2, R.sub.3, R.sub.4 and X are as herein defined have been found to be useful prodrug and exhibit anticonvulsant activity when converted to the active agent upon administration to a mammal and are thus useful in the treatment of conditions such as epilepsy. Further, the present invention encompasses pharmaceutical compositions containing a compound of formula (I) as well as methods for their use.

Abstract: Novel oxolabdanes, intermediates and processes for the preparation thereof, and methods for reducing intraocular pressure utilizing compounds or compositions thereof are disclosed.

Abstract: Compounds of the general formula (I): ##STR1## wherein R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5, R.sub.6, n and p are as herein defined; exhibit anticonvulsant activity and are thus useful in the treatment of conditions such as epilepsy. Compounds of this class are also useful for the treatment of glaucoma, peptic ulcers, hypertension, congestive heart failure and other types of edema. Furthermore, pharmaceutical compositions containing a compound of formula (I) as well as methods for their use and novel intermediates are disclosed.

Abstract: Certain aryl substituted naphthalene, benzoxepine, benzazepine and henzocycloheptene derivatives are disclosed. The compounds are useful in treating hyperproliferative skin disease, allergic reactions and inflammation.

Abstract: The reaction of 5,6,11,12-tetrachlorotetracene with thiourea and sulfur in a polar aprotic solvent yields 5,6,11,12-tetrathiotetracene in high yield and purity. This compound is an electron donor for forming electrically conductive radical cation salts with electron donors.

Abstract: As a result of the action of electron acceptors, for example chlorine, bromine and/or iodine, on compositions containing a linear, branched or structurally crosslinked polymer and an unsubstituted or substituted tetrathionaphthalene, tetraselenonaphthalene, tetratelluronaphthalene, tetrathiotetracene, tetraselenotetracene or tetratellurotetracene, electrical conductivity is imparted to the compositions through the formation of charge-transfer complexes. These compositions are suitable for the production of mouldings, filaments, fibres, coatings and composite materials which have an antistatic finish or are electrically conducting.

Abstract: A charge transfer complex formed between a benzoquinone derivative represented by formula ##STR1## wherein at least one of the rings A and B represents a heterocyclic ring as defined in the specification, and an electron donor, and a salt of an anion or anion radical of the benzoquinone derivative of the above formula are disclosed. The charge transfer complex and the salt are useful as electronic materials.

Abstract: There is provided a novel and efficient stereoselective total synthesis of epipodophyllotoxin and related epipodophyllotoxin compounds of the and present invention ##STR1## wherein R.sup.1 and R.sup.2 each are independently hydrogen or (lower)alkoxy, or R.sup.1 ll and R.sup.2, taken together, is methylenedioxy; R.sup.4 and R.sup.6 each are independently hydrogen or (lower)alkoxy; and R.sup.5 is hydrogen or a phenol-protecting group; or an acid addition salt thereof. The present ivnention also provides novel intermediates and processes for the preparation of said intermediates, which are then converted into known antineoplastic agents.

Abstract: A process for the preparation of novel 14.alpha., 17.alpha.-dihydroxy-17.beta.-substituted steroids by reacting 14.alpha.-hydroxy-17-oxo-steroids with metal organic compounds and the use of the said novel steroids in the production of 14.alpha., 17.alpha.-methylenedioxy-pregnane derivatives.

Abstract: This invention relates to novel 3-substituted-2-oxindole derivatives which are inhibitors of prostaglandin H.sub.2 synthase, 5-lipoxygenase and interleukin-1 biosynthesis. The compounds of the invention are useful as inhibitors of prostaglandin H.sub.2 synthase and interleukin-1 biosynthesis, per se, and as analgesic, antiinflammatory and antiarthritic agents in the treatment of chronic inflammatory diseases. This invention also relates to pharmaceutical compositions comprising said 3-substituted-2-oxindole derivatives; to methods of inhibiting prostaglandin H.sub.2 synthase and biosynthesis of interleukin-1; and to treating chronic inflammatory diseases in a mammal with said compounds. Further, this invention relates to certain novel carboxylic acids useful as intermediates in the preparation of the 3-substituted-2-oxindole derivatives of this invention and to a process for the preparation of the 3-substituted-2-oxindole derivatives.

Abstract: Substituted tetrathiotetracenes and tetraselenotetracenes of the formula I ##STR1## in which Z is --S-- or --Se-- and (a) R.sup.1, R.sup.2, R.sup.3 and R.sup.4 are H and R.sup.5 to R.sup.8 are each H and at least one of the radicals R.sup.5 to R.sup.8 independently of one another is a substituent belonging to the group comprising C.sub.1 -C.sub.20 alkyl--X--.sub.p which is unsubstituted or substituted by halogen, --CN, --CONR.sup.9 R.sup.10, --OR.sup.9, --SR.sup.9 or --COOR.sup.9, with the exception of C.sub.1 -C.sub.4 alkyl and methoxy, C.sub.2 -C.sub.18 alkenyl--X--.sub.p, C.sub.2 -C.sub.18 -alkynyl--X--.sub.p, C.sub.3 -C.sub.8 cycloalkyl--X--.sub.p, (C.sub.1 -C.sub.12 alkyl)--C.sub.3 -C.sub.8 cycloalkyl--X--.sub.p, C.sub.3 -C.sub.8 cycloalkyl-C.sub.r H.sub.2r --X--.sub.p, (C.sub.1 -C.sub.12 alkyl)-C.sub.3 -C.sub.8 -cyclo alkyl-C.sub.r H.sub.2r --X--.sub.p, phenyl--X--.sub.p, (C.sub.1 -C.sub.12)alkyl)-phenyl--X--, phenyl-C.sub.r H.sub. 2r --X--.sub.p and (C.sub.1 -C.sub.12 alkyl)-phenyl-C.sub.r H.sub.

Abstract: Compounds of the formula ##STR1## in which Ar is substituted or unsubstituted phenyl, naphthyl, or thienyl; and Ar.sup.1 is 3-phenoxyphenyl, 4-fluoro-3-phenoxyphenyl, 2-methyl[1-1'-biphenyl]-3-yl, or 6-phenoxy-2-pyridyl, exhibit pyrethroid-like insecticidal and acaricidal activity and are relatively nontoxic to fish.

Abstract: A method for preparation of 1,3-oxathiolanes is described. The method comprises reacting, in a solvent, a fluoride ion source, a carbonyl compound, and a halomethyl trimethylsilylmethyl sulfide, wherein the halomethyl trimethylsilyl methyl sulfide is selected from a group consisting of chloromethyl trimethylsilylmethyl sulfide, bromomethyl trimethylsilylmethyl sulfide, or iodomethyl trimethylsilylmethyl sulfide.

Abstract: Novel labdanes, intermediates and processes for the preparation thereof, and methods for reducing intraocular pressure utilizing compounds or compositions thereof are disclosed.

Abstract: A charge transfer complex formed between a benzoquinone derivative represented by formula ##STR1## wherein at least one of the rings A and B represents a heterocyclic ring as defined in the specification, and an electron donor, and a salt of an anion or anion radical of the benzoquinone derivative of the above formula are disclosed. The charge transfer complex and the salt are useful as electronic materials.

Abstract: A compound represented by formula (I): ##STR1## wherein R represents a straight chain alkyl group having from 1 to 9 carbon atoms; ##STR2## represents ##STR3## represents a hydrogen atom or a fluorine atom; and ##STR4## has a trans (equatorial-equatorial) configuration, is disclosed. The compound of formula (I) exhibits a nematic phase in the vicinity of room temperature or in a temperature range higher than room temperature and has a small optical anisotropy and a positive dielectric anisotropy and is, therefore, useful in preparing a liquid crystal display cell excellent in viewing-angle characteristics.

Abstract: Tetralin derivatives of the formula I ##STR1## where X, R.sup.1, R.sup.2 and R.sup.3 have the meanings stated in the description, and their preparation are described. The novel compounds are useful for the treatment of disorders.

Abstract: Novel oxolabdanes, intermediates and processes for the preparation thereof, and methods for reducing intraocular pressure utilizing compounds or compositions thereof are disclosed.

Abstract: Novel labdanes, intermediates and processes for the preparation thereof, and methods for reducing intraocular pressure utilizing compounds or compositions thereof are disclosed.

Abstract: Novel aminoacyllabdanes, intermediates and processes for the preparation thereof, and methods for reducing intraocular pressure utilizing compounds or compositions thereof are disclosed.

Abstract: Novel condensation polymers are of the unit formula--O--A--OCO--B--CO--,--O--A--OOCNH--D--NHCO--, or--O--CH.sub.2 CHOHCH.sub.2 --O--A--O--CH.sub.2 CHOHCH.sub.2 O--E--wherein A is the residue of a substituted or unsubstituted 8,9-bis(hydroxyalkyl)-exo-3,4,5-trithiatricyclo[5.2.1.0.sup.2,6 ]decane of the formula ##STR1## B is the residue of a substituted or unsubstituted aliphatic, cycloaliphatic or aromatic dicarboxylic acid; D is the residue of a substituted or unsubstituted aliphatic, cycloaliphatic or aromatic diisocyanate; E is the residue of a substituted or unsubstituted aliphatic, cycloaliphatic or aromatic dihydroxylic chain extender for a diglycidyl ether of the trithiatricyclo[5.2.1.0.sup.2,6 ]decane and n is 1-10.

Abstract: 2- or 2,3-substituted 5,6,11,12-tetraseleneotetracene or -tetrathiotetracene of the formula ##STR1## in which X is S or Se, R is alkoxy, hydroxyalkoxy, aryloxy, cycloalkoxy, aralkoxy, --OH, --NH.sub.2, --Cl, --Br or substituted amino and Y is hydrogen or --COR. The compounds can be bonded as side groups to polymers. The polymers and the compounds combine with electron acceptors to form charge transfer complexes which can be used as electrically conductive layers.

Abstract: The invention relates to oxothienobenzoxepin compounds of the formula ##STR1## where X together with the carbon atoms to which it is attached is a thiophene ring;R.sub.1 is hydrogen, a straight or branched chain alkyl group having 1 to 5 carbon atoms or a halogen atom;R.sub.2 is hydrogen or a straight chain alkyl group having 1 to 5 carbon atoms; andR.sub.3 is hydroxyl or ##STR2## where R.sub.4 is a straight chain or branched chain alkyl group having 1 to 10 carbon atoms, a phenyl group or a trifluoromethyl group. Methods for preparing the compounds and their use as antiinflammatory and analgesic agents are provided.

Abstract: Compounds of the formula ##STR1## and the pharmaceutically acceptable, nontoxic, acid addition salts thereof, whereinR.sub.1 and R.sub.2 are each independently --H, lower alkyl, or cycloalkyl, with the proviso that R.sub.1 and R.sub.2 cannot both be --H or cycloalkyl at the same time;R.sub.1 and R.sub.2 taken together are cycloalkyl of 4-7 carbons;n is 0 or 1;X is (CH.sub.2).sub.2, CH.dbd.CH, or C.tbd.C;Y is independently selected from the group of --H, --Fl, --Br, --Cl, lower alkyl, and --OR.sub.3 ; wherein R.sub.3 is --H or lower alkyl; anda is 1 or 2, ortwo Y's taken together are --OCH.sub.2 O--;are useful as regulators of the cardiovascular system, particularly as hypotensive agents.

Abstract: Compounds of the formula I ##STR1## wherein R.sub.1 is ##STR2## wherein R.sup.I and R.sup.II each independently is alkyl of 1-4 carbon atoms, or R.sup.I and R.sup.II together with the connecting N-atom form a 5- or 6-membered heterocyclic ring whose remaining atoms are all C-atoms, or which also includes and additional N-atom, an additional O or S atom or a combination thereof; ##STR3## wherein R.sup.I and R.sup.II are as defined above; --SR.sup.III, wherein R.sup.III is methyl, ethyl or phenyl; or--OR.sup.IV, wherein R.sup.IV is methyl, ethyl, propyl, methoxymethyl, allyl, or .beta.-dimethylaminoethyl;R.sub.2 is hydrogen, methyl, or ethyl; ##STR4## wherein the wavy lines mean that the substituent is in the .alpha.- or .beta.-position, and ##STR5## M is Na, K or Li; and R.sup.V, R.sup.VI, R.sup.VII and R.sup.VIII each independently is alkyl of 1-4 carbon atoms, have valuable pharmacological properties, e.g., a combination of antiprogestational and antimineralocorticordal effects.

Abstract: Chalcogen-substituted perylenes of the formula I ##STR1## wherein X is S or Se can be obtained in a simple manner, under mild reaction conditions and in pure form by heating a compound of the formula II ##STR2## in nitrobenzene, or in a mixture of nitrobenzene and an organic solvent miscible therewith and inert under the reaction conditions, in the presence of a Lewis acid or a protonic acid at 20.degree. to 120.degree. C. The perylenes of the formula I are used for example as donors for the production of organic conductors or semiconductors (charge-transfer-salts).

Abstract: The invention relates to oxothienobenzoxepin compounds of the formula ##STR1## where X together with the carbon atoms to which it is attached is a thiophene ring;R.sub.1 is hydrogen, a straight or branched chain alkyl group having 1 to 5 carbon atoms or a halogen atom;R.sub.2 is hydrogen or a straight chain alkyl group having 1 to 5 carbon atoms; andR.sub.3 is hydroxyl or ##STR2## where R.sub.4 is a straight chain or branched chain alkyl group having 1 to 10 carbon atoms, a phenyl group or a trifluoromethyl group.Methods for preparing the compounds and their use as antiinflammatory and analgesic agents are provided.

Abstract: The pyrolysis of aromatic compounds with fused rings in the aromatic system which form free radicals on the peri position, for example, by eliminating a stable inorganic gas produces desirable products. These products include electrically conductive inert films. Further, with the addition of suitable inorganic compounds to the reactant, superconducting materials are obtainable. The addition of sulfur to the pyrolysis reactant also is possible and allows production of compounds useful as donors for the production of organic electrically conducting compositions.

Abstract: 3,4,5-Trithiatricyclo[5.2.1.0.sup.2,6 ]decanes and derivatives are prepared in high yield by contacting a bicyclo[2.2.1]hept-2-ene compound and sulfur in the presence of a solvent, and a catalytic amount of sulfide ions.

Abstract: A novel metallically conducting charge-transfer complex derived from 5,6,11,12-tetrathiotetracene and iodine is described. This complex is preferably produced by reacting 5,6,11,12-tetrathiotetracene and iodine together in the gas phase in an inert-gas atmosphere. The novel complex is characterized by a very high electrical conductivity, and it can be used, for example, as an organic conductor element.

Abstract: The invention relates to (1.alpha., 2.alpha., 4.alpha., 6.alpha.)-3-oxatricyclo[4.2.0.0.sup.2,4 ]octane-7-one and derivatives thereof in which the ketone group is protected, which compounds are useful intermediates in the preparation of natural and synthetic prostaglandins. Processes for the preparation of these compounds are described and exemplified as are processes for their conversion into known prostaglandin intermediates.

Abstract: Tricyclic nitrogenous compounds having strong plant growth regulating properties are disclosed. The compounds display the general formula ##STR1## wherein A is one of several nitrogen-containing radicals, R.sup.1, R.sup.2, R.sup.3 and R.sup.4 are selected from various recited aliphatic, aryl, araliphatic and heterocyclic groups. R.sup.3 and R.sup.4 may also together form one of a number of nitrogen, sulfur and oxygen containing radicals. These compounds have a variety of uses, including the reduction of plant growth height without harm to the plant.