Three Or More Ring Oxygens In The Hetero Ring Patents (Class 549/367)
  • Patent number: 10743443
    Abstract: A power distribution device comprising a supporting structure having a power input connector mounted to the supporting structure, the power input connector having at least two input contacts and a power output connector mounted to the supporting structure, the power output connector having at least two output contacts corresponding to the at least two input contacts. A plurality of elongated filters are mounted inside the supporting structure, each one of the filters comprising a hollow casing filled with a mixture composed of quartz and bitumen emulsion, wherein a percent of bitumen emulsion of a total volume of the mixture is greater than 0% and no more than 50%. Wire connections define first electric paths from the input contacts to the elongated filters and second electric paths from the elongated filters to the output contacts.
    Type: Grant
    Filed: October 11, 2019
    Date of Patent: August 11, 2020
    Inventor: Daniel Robidoux
  • Patent number: 9845553
    Abstract: The present invention concerns methods for removing sulfur from yarn comprising the steps of: a) contacting never-dried polymeric yarn with an aqueous base, the polymer comprising imidazole groups and said polymer comprising sulfur atoms characterized as being in the form of sulfate anions; b) contacting the yarn with an aqueous acid solution of pH 5 or lower; and c) rinsing the yarn.
    Type: Grant
    Filed: January 11, 2012
    Date of Patent: December 19, 2017
    Assignee: E I DU PONT DE NEMOURS AND COMPANY
    Inventors: Steven R. Allen, Vlodek Gabara, Joseph Lenning Lowery, Christopher William Newton, David J. Rodini, Andrew J. Sitter
  • Publication number: 20140343302
    Abstract: A process for recycling polyoxymethylene polymers is disclosed. A polyoyxmethylene polymer is at least partially dissolved in an aprotic compound. The resulting solution or suspension (liquid mixture) is then contacted with a catalyst which causes the polyoxymethylene polymer to be converted into a cyclic acetal. The cyclic acetal can be separated, collected and used in other processes. In one embodiment, the cyclic acetal may be used to produce a polyoxymethylene polymer.
    Type: Application
    Filed: November 23, 2012
    Publication date: November 20, 2014
    Inventors: Michael Haubs, Jurgen Lingnau, Klaus Kurz
  • Publication number: 20140343300
    Abstract: The present invention relates to a process for producing cyclic acetal comprising i) preparing a liquid reaction mixture comprising a) a formaldehyde source, b) an aprotic compound and c) a catalyst; wherein the total amount of protic compounds is less than 40 wt.-%, based on the total weight of the reaction mixture; and ii) converting the formaldehyde source into cyclic acetals.
    Type: Application
    Filed: November 23, 2012
    Publication date: November 20, 2014
    Inventors: Michael Haubs, Jürgen Lingnau, Klaus Kurz
  • Publication number: 20140343301
    Abstract: The present invention relates to a process for producing cyclic acetal comprising i) preparing a reaction mixture comprising a) a formaldehyde source in a liquid medium and b) a catalyst; ii) converting the formaldehyde source into cyclic acetals, wherein the final conversion of said formaldehyde source to said cyclic acetal is greater than 10% on basis of the initial formaldehyde source.
    Type: Application
    Filed: November 23, 2012
    Publication date: November 20, 2014
    Inventors: Michael Haubs, Klaus Kurz, Jürgen Lingnau
  • Publication number: 20140329988
    Abstract: A process for producing cyclic acetals is described. A formaldehyde source is contacted with an aprotic compound in the presence of a catalyst to produce the cyclic acetals. The aprotic compound can increase conversion rates and/or efficiency. In one embodiment, the formaldehyde source is obtained from methanol. In particular, methanol can be converted into formaldehyde which is then converted into a cyclic acetal. In one embodiment, the cyclic acetal can then be used to produce oxymethylene polymers.
    Type: Application
    Filed: November 23, 2012
    Publication date: November 6, 2014
    Inventors: Michael Haubs, Michael Hoffmockel, Klaus Kurz, Jurgen Lingnau, Damian Feord
  • Publication number: 20140323686
    Abstract: A process for recovering volatile components from an oxymethylene polymer process is disclosed. The volatile components are removed from the process and the formaldehyde collected is converted to a cyclic acetal. The formaldehyde is converted to a cyclic acetal by contacting the formaldehyde with a catalyst in the presence of an aprotic solvent.
    Type: Application
    Filed: November 23, 2012
    Publication date: October 30, 2014
    Inventors: Klaus Kurz, Jurgen Lingnau, Michael Haubs, Michael Hoffmockel, Damian Feord
  • Patent number: 8815844
    Abstract: The present invention relates to the compounds useful in the prevention and/or treatment of tumors. More specifically the present invention relates to inhibitors of the activity of the electron transport chains and/or the mitochondrial TCA cycle in glioma-initiating cells (GICs) for use in a method for preventing and/or treating tumors presenting glioma-initiating cells (GICs) in a subject who has undergone a prior removal of a tumor glioma bulk. The present invention further provides a pharmaceutical composition containing the inhibitors of the invention and a screening method for identifying the inhibitors of the invention.
    Type: Grant
    Filed: May 20, 2010
    Date of Patent: August 26, 2014
    Assignees: Universite de Geneve, Hopitaux Universitaires de Geneve
    Inventors: Virginie Clement, Ivan Radovanovic
  • Publication number: 20120330032
    Abstract: A process for making a cyclic compounds such as cyclic acetal or cyclic ketones by feeding aldehyde or ketone compounds and polyhydroxyl compounds to a reaction zone at a molar ratio of polyhydroxyl compounds to aldehyde or ketone compounds of at least 3:1, reacting these compounds in the presence of a solid acid such as an acidic ion exchange resin, to generate a liquid reaction mixture without separating water from the reaction mixture as it is being formed in the reaction mixture, withdrawing the liquid reaction mixture from the reaction zone as a liquid product stream, and feeding the liquid reaction product stream to a distillation column to separate cyclic acetal compounds from unreacted polyhydroxyl compounds, and optionally recycling back the unreacted polyhydroxyl compounds to the reaction zone. The process produces cyclic acetal compounds in yields of at least 90% with long catalyst life. The process is also suitable to make cyclic ketals from ketone compounds.
    Type: Application
    Filed: June 24, 2011
    Publication date: December 27, 2012
    Applicant: EASTMAN CHEMICAL COMPANY
    Inventors: Daniel Latham Terrill, Brian David McMurray, Damon Ray Billodeaux, James Lon Little, Adam Scott Howard
  • Publication number: 20100273193
    Abstract: This disclosure is drawn to a triacetone triperoxide derivative in accordance with the general formula (I) and a diacetone diperoxide derivative in accordance with the general formula (II) wherein R1 is a hydrogen residue or an optionally halogenated or perhalogenated C1 to C5 alkyl group, R2 represents a linker molecule, and X represents a reactive or activatable group. A method for the preparation of the TATP or DADP derivatives and the use thereof as antigen for the preparation of TATP- or DADP-specific antibodies or other binders is also disclosed. The antibodies are preferably used in a biosensor for the detection of TATP or DADP in air.
    Type: Application
    Filed: April 26, 2010
    Publication date: October 28, 2010
    Applicant: BAM Bundesanstalt fur Materialforschung und-pruefung
    Inventors: Astrid Walter, Rudolf J. Schneider, Michael G. Weller
  • Publication number: 20070231300
    Abstract: The invention relates to covalent conjugates between endoperoxides and small peptides and organic compounds that bind to molecular cavities on the transferrin or lactoferrin receptor, and the use of compositions comprising these conjugates to treat cancer, hyperproliferative disorders, inflammatory diseases, and infections.
    Type: Application
    Filed: March 28, 2007
    Publication date: October 4, 2007
    Applicant: WASHINGTON, UNIVERSITY OF
    Inventors: Tomikazu Sasaki, Henry Chiu-Yuen Lai, Narendra Pal Singh, Steve J. Oh
  • Patent number: 7244854
    Abstract: The present invention relates to a method of synthesizing trioxymethylene from formaldehyde by the catalytic action of an acidic ionic liquid. In the method, formaldehyde solution with a concentration of 30˜80 wt % is used as reactant, and an ionic liquid is used as catalyst. The cation moiety of the catalyst is selected from either imidazoles cation or pyridines cation, and the anion moiety of the catalyst is selected from one of p-tolyl benzene sulfonate, trifluoromethyl sulfonate, and hydrogen sulfate. In the present invention, ionic liquid is used, for the first time, as a catalyst to synthesize trioxymethylene from formaldehyde. The catalyst can be circularly used for continuous sampling.
    Type: Grant
    Filed: December 8, 2006
    Date of Patent: July 17, 2007
    Assignee: Lanzhou Institute of Chemical Physics Chinese Academy of Sciences
    Inventors: Chungu Xia, Zhonghua Tang, Jing Chen, Xinzhi Zhang, Zhen Li, Enxiu Guo
  • Publication number: 20040230064
    Abstract: This invention relates to resiniferatoxin derivatives useful in a vanilloid receptor binding assay and methods for production thereof.
    Type: Application
    Filed: October 9, 2001
    Publication date: November 18, 2004
    Inventors: Mark E. McDonnell, Larry E. Weaner, Sui Po Zhang
  • Patent number: 6753127
    Abstract: Disclosed is an norbornene-based copolymer for photoresist, a preparation method thereof, and a photoresist composition comprising the same. The copolymer of the present invention exhibits high transparency to light of 193 nm wavelength and an excellent etching resistance, excellent resolution due to the remarkable difference between light-exposed part and light-unexposed part in the dissolving rate and excellent adhesion to the substrate due to very hydrophilic diketone group of its own. As a result, the copolymer of the present invention is very useful as ArF exposure photoresist material in the fabrication of semiconductor devices.
    Type: Grant
    Filed: September 19, 2002
    Date of Patent: June 22, 2004
    Assignee: Samsung Electronics Co., Ltd.
    Inventors: Eun Sil Han, Bong Seok Moon, Jung Han Shin, Ouck Han
  • Publication number: 20030118933
    Abstract: Disclosed is an norbornene-based copolymer for photoresist, a preparation method thereof, and a photoresist composition comprising the same. The copolymer of the present invention exhibits high transparency to light of 193 nm wavelength and an excellent etching resistance, excellent resolution due to the remarkable difference between light-exposed part and light-unexposed part in the dissolving rate and excellent adhesion to the substrate due to very hydrophilic diketone group of its own. As a result, the copolymer of the present invention is very useful as ArF exposure photoresist material in the fabrication of semiconductor devices.
    Type: Application
    Filed: September 19, 2002
    Publication date: June 26, 2003
    Inventors: Eun Sil Han, Bong Seok Moon, Jung Han Shin, Ouck Han
  • Patent number: 6462074
    Abstract: The present invention relates to novel substituted (&agr;,&bgr;-fused butyrolactones, to processes for their preparation and to their use for the prevention and/or treatment of disorders caused by hyper- or hypofunction of the glutamatergic system, in particular of cerebral ischaemias, craniocerebral trauma, states of pain or CNS-mediated spasms.
    Type: Grant
    Filed: July 14, 2000
    Date of Patent: October 8, 2002
    Assignee: Bayer Aktiengesellschaft
    Inventors: Andreas Stolle, Horst-Peter Antonicek, Stephen Lensky, Arnd Voerste, Thomas Müller, Jörg Baumgarten, Karsten von dem Bruch, Gerhard Müller, Udo Stropp, Ervin Horváth, Jean-Marie-Viktor de Vry, Rudy Schreiber
  • Patent number: 5962702
    Abstract: A process for producing trioxane by contacting an aqueous formaldehyde solution comprising 67 wt. % formaldehyde, 30 wt. % water and 3 wt. % methanol with an acidic catalyst comprising a cation exchange resin containing a sulfonic acid group. The concentration of methanol, and formic acid which is generated during the reaction, are both controlled between 0.5-5.0 wt. % and the concentration of methanol in terms of wt. % is controlled so as not to exceed two times the concentration of formic acid in terms of wt. %. With this process, the amounts of by-products formed are small, and trioxane can be produced efficiently.
    Type: Grant
    Filed: April 24, 1997
    Date of Patent: October 5, 1999
    Assignee: Asahi Kasei Kogyo Kabushiki Kaisha
    Inventor: Hirohisa Morishita
  • Patent number: 5824677
    Abstract: Disclosed are compounds having a straight or branched aliphatic hydrocarbon structure of formula I: ##STR1## In formula I, n is an integer from one to four and m is an integer from four to twenty. Independently, R.sub.1 and R.sub.2 are hydrogen, a straight or branched chain alkyl, alkenyl or alkynyl of up to twenty carbon atoms in length or --(CH.sub.2).sub.w R.sub.5. If R.sub.1 or R.sub.2 is --(CH.sub.2).sub.w R.sub.5, w may be an integer from one to twenty and R.sub.5 may be an hydroxyl, halo, C.sub.1-8 alkoxyl group or a substituted or unsubstituted carbocycle or heterocycle. Alternatively, R.sub.1 and R.sub.2 may jointly form a substituted or unsubstituted, saturated or unsaturated heterocycle having from four to eight carbon atoms, N being a hetero atom of the resulting heterocyle. R.sub.3 may be either hydrogen or C.sub.13. In the compounds, a total sum of carbon atoms comprising R.sub.1 or R.sub.2, (CH.sub.2).sub.n and (CH.sub.2).sub.m does not exceed forty. R.sub.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: October 20, 1998
    Assignee: Cell Therapeutics, Inc.
    Inventors: J. Peter Klein, Gail E. Underiner, Anil M. Kumar
  • Patent number: 5348890
    Abstract: Trioxane derivatives represented by the formula (I): ##STR1## wherein A and RA are the same with or different from each other, and represent a substituted or unsubstituted aliphatic hydrocarbon group, respectively, or represent R.sub.1 --X.sub.1 --or R.sub.2 --X.sub.2 --in which X.sub.1 and X.sub.2 represent independently a divalent organic residue, and R.sub.1 and R.sub.2 represent independently carboxyl group, amino group, hydroxyl group or mercapto group, and Z represents hydrogen atom, halogen atom, methyl group, ethyl group or propyl group, or carboxyl, amino, hydroxyl or mercapto group through a divalent organic residue, and process for the preparation thereof, as well as method for chemiluminescence comprising mixing the trioxane derivatives and a base.
    Type: Grant
    Filed: December 4, 1992
    Date of Patent: September 20, 1994
    Assignee: NOF Corporation
    Inventors: Shuji Ichikawa, Motohiro Mitani, Yuko Yokoyama, Hideo Sawada, Takeo Matsumoto
  • Patent number: 5225437
    Abstract: Novel 1,2,4-trioxanes which possess anti-malarial activity.
    Type: Grant
    Filed: January 23, 1992
    Date of Patent: July 6, 1993
    Assignee: The Johns Hopkins University
    Inventors: Gary Posner, Chang H. Oh
  • Patent number: 5166368
    Abstract: A process of producing a high-pure dichloroacetaldehyde trimer with high yield by cyclodehydrating dichloroacetaldehyde hydrate in the presence of concentrated sulfuric acid.
    Type: Grant
    Filed: April 25, 1991
    Date of Patent: November 24, 1992
    Assignee: Kureha Chemical Industry Co., Ltd.
    Inventors: Makoto Ishizuka, Takashi Wakasugi
  • Patent number: 5164518
    Abstract: The present invention provides a method for the alpha,omega-arylation/alkylation of a non-conjugated diene in one step by reacting the diene with an aryl iodide or an aryl bromide and a carbon nucleophile in the presence of an amount of a Pd(O) complex effective to catalyze the reaction.
    Type: Grant
    Filed: July 12, 1991
    Date of Patent: November 17, 1992
    Assignee: Iowa State University Research Fondation Inc.
    Inventor: Richard C. Larock
  • Patent number: 4947005
    Abstract: 1,1,2-Trialkoxyethanes of the general formula I ##STR1## where R.sup.1 to R.sup.3 are each independently of the others C.sub.1 -C.sub.20 -alkyl or cycloalkyl, or R.sup.1 and R.sup.2 may be linked together to form a 5-, 6- or 7-membered ring, are prepared by reacting formaldehyde dialkyl acetals of the general formula II ##STR2## where R.sup.1 and R.sup.2 are each as defined above, or compounds which are capable of forming formaldehyde dialkyl acetals under the reaction conditions, with carbon monoxide, hydrogen and alkanols R.sup.3 OH under superatmospheric pressure at elevated temperature in the presence of a catalyst composed of a cobalt carbonyl compound and a promotor, wherein the promotor is an alkali metal, alkaline earth metal or ammonium salt of a protogenic compound having an acid constant K.sub.a of from 10.sup.-2 to 10.sup.-14, an alkali metal or alkaline earth metal hydroxide or an aminocarboxylic acid.
    Type: Grant
    Filed: August 25, 1989
    Date of Patent: August 7, 1990
    Assignee: BASF Aktiengesellschaft
    Inventors: Dieter Koeffer, Werner Bertleff
  • Patent number: 4725682
    Abstract: Sulfur-containing bis-amino carbamate compounds exhibit outstanding acaricidal, nematocidal and insecticidal activity.
    Type: Grant
    Filed: December 2, 1986
    Date of Patent: February 16, 1988
    Assignee: Rhone-Poulenc Nederland, B.V.
    Inventor: Themistocles D. J. D'Silva
  • Patent number: 4701556
    Abstract: The invention relates to a process for the manufacture of a cephalosporin derivative of the formula I: ##STR1## in which X is a sulphur or oxygen atom or a sulphinyl radical, R.sup.1 is any one of the C-3 substituents from antibacterially-active cephalosporins known in the art, R.sup.2 is a hydrogen atom or a 1-6C alkyl or 2-6C alkenyl radical, R.sup.3 is a hydrogen atom or one of a variety of radicals defined in the specification, and the pharmaceutically-acceptable acid- and base-addition salts thereof, characterized by reaction of a compound of the formula IX: ##STR2## in which R.sup.16 and R.sup.17 individually have one of the values given above for R.sup.2 and R.sup.3, or a derivative thereof in which the carbonyl group is masked, with a compound of the formula X: ##STR3## in which R.sup.18 is a hydrogen atom or any one of the cephalosporin 3-carboxylic acid protecting groups known in the art; whereafter, when R.sup.18 is other than a hydrogen atom, the protecting group R.sup.
    Type: Grant
    Filed: November 29, 1984
    Date of Patent: October 20, 1987
    Assignee: Imperial Chemical Industries PLC
    Inventor: Frank Loftus
  • Patent number: 4540835
    Abstract: A process of preparing 2-trifluoromethylpropanol by vapor phase contact reaction between 2-trifluoromethylpropanal trimer and hydrogen in the presence of a catalyst of which the principal component is reduced nickel. The hydrogenation reaction can easily be completed at about 30.degree.-150.degree. C. and at the atmospheric pressure. The starting material is hydrogenated nearly theoretically and with very high selectivity factor for 2-trifluoromethylpropanol.
    Type: Grant
    Filed: May 17, 1984
    Date of Patent: September 10, 1985
    Assignees: Central Glass Company Limited, Sagami Chemical Research Center
    Inventors: Toshikazu Kawai, Akira Negishi, Iwao Ojima, Takamasa Fuchikami
  • Patent number: 4330474
    Abstract: A process for preparing a cyclic acetal from a saturated, aliphatic aldehyde comprises contacting a saturated, aliphatic aldehyde of 2-16 carbon atoms with a silica gel.
    Type: Grant
    Filed: May 25, 1979
    Date of Patent: May 18, 1982
    Assignee: Chemische Werke Huels, A.G.
    Inventor: Rudolf Nehring