Having -c(=x)-, Wherein X Is Chalcogen, Attached Indirectly To The Hetero Ring By Nonionic Bonding Patents (Class 549/496)
  • Patent number: 4487960
    Abstract: Novel compounds of the following formula: ##STR1##
    Type: Grant
    Filed: April 19, 1982
    Date of Patent: December 11, 1984
    Assignee: The Upjohn Company
    Inventor: Chiu-Hong Lin
  • Patent number: 4479002
    Abstract: Carbamate-carbamoyl fluoride compounds are useful intermediates for the production of insecticidal bis-carbamate compounds.
    Type: Grant
    Filed: December 1, 1975
    Date of Patent: October 23, 1984
    Assignee: Union Carbide Corporation
    Inventor: Wei C. Liang
  • Patent number: 4474808
    Abstract: N-Sulphenylated biuret-N"-carboxylic acid esters of the general formula ##STR1## in which R.sup.1 and R.sup.2 can be identical or different and represent an optionally substituted aliphatic, cycloaliphatic, aromatic or araliphatic radical,R.sup.3 represents a hydrogen atom or an optionally substituted aliphatic, cycloaliphatic, araliphatic or aromatic radical andR.sup.4 represents a trihalogenomethyl radical,are obtained by the reaction of an acyl isocyanate of the general formula ##STR2## with a sulphenamide of the general formula ##STR3## if appropriate in the presence of a diluent. The compounds of the formula (I) are new. They can be used as pest-combating agents which are microbicides, especially fungicides or bactericides.
    Type: Grant
    Filed: November 3, 1982
    Date of Patent: October 2, 1984
    Assignee: Bayer Aktiengesellschaft
    Inventors: Engelbert Kuhle, Paul Reinecke, Karl-Heinz Kuck
  • Patent number: 4466822
    Abstract: Novel oxime ethers and oxime esters of the formula I given herein have various advantageous effects with regard to stimulation of plant growth, particularly in the early stage of development of the plant. Furthermore, such compounds have the property of rendering, in the sense of an antidote action, agricultural chemicals which would otherwise damage the plants (phytotoxic chemicals) more compatible with the cultivated plants. Herbicides that are insufficiently selective can be used for example in the presence of such oxime derivatives in specific cultivated crops for combating weeds, without disadvantageous consequences for the cultivated plants.
    Type: Grant
    Filed: March 11, 1980
    Date of Patent: August 21, 1984
    Assignee: Ciba-Geigy Corporation
    Inventor: Henry Martin
  • Patent number: 4459308
    Abstract: There are described 2,2-dimethyl-cyclopropanecarboxylates having in position 3 of the cyclopropane ring, a polyhalogenated chain having from 3 to 6 carbon atoms.Said compounds are insecticide and acaricide compounds with a high activity and long persistence.There is also described the use of the above mentioned compounds, as well as the synthesys processes and the corresponding intermediates.
    Type: Grant
    Filed: July 27, 1981
    Date of Patent: July 10, 1984
    Assignee: Montedison S.p.A.
    Inventors: Francesco Corda, Franco Gozzo, Vincenzo Caprioli
  • Patent number: 4458090
    Abstract: Novel .gamma.-lactone derivatives are provided. These lactone derivatives, when reacted with hydrogen halide in alcohol, yield .gamma.-halogeno-.delta.-unsaturated carboxylic acid esters. This ring-opening process is useful for the purpose of increasing the yield of pyrethrin analogs which are of value as insecticides and agricultural chemicals. Thus, the .gamma.-lactone derivatives by-produced in the production process for dihalogenovinyl chrysanthemumates are caused to undergo ring-opening reaction to yield the corresponding .gamma.-halogeno-.delta.-unsaturated carboxylic acid esters which are important intermediates for said pyrethrin analogs.
    Type: Grant
    Filed: October 15, 1981
    Date of Patent: July 3, 1984
    Assignee: Kuraray Co., Ltd.
    Inventors: Mori Fumio, Omura Yoshiaki, Nishida Takashi, Itoi Kazuo
  • Patent number: 4458077
    Abstract: Compounds of the formulaAr--(CH.sub.2).sub.m --X--(CH.sub.2).sub.n --ONHRwherein R is ##STR1## wherein R.sup.1 is hydrogen or lower alkyl;X is O or CH.sub.2 ;m=0 or 1;n=2 or 3; andAr is a moiety selected from the group ##STR2## wherein R.sub.2 is hydrogen or lower alkyl, ##STR3## with the proviso that when Ar is ##STR4## and X is CH.sub.2, then R is other than ##STR5## and the pharmacologically acceptable salts thereof have H.sub.2 -antagonist activity and activity in decreasing gastric acid secretions.
    Type: Grant
    Filed: November 22, 1982
    Date of Patent: July 3, 1984
    Assignee: American Home Products Corporation
    Inventor: John R. Potoski
  • Patent number: 4451285
    Abstract: The present disclosure relates to a new class of 2-haloacetanilide derivatives which are useful as herbicides. This disclosure further relates to herbicidal compositions containing such 2-haloacetanilides and to herbicidal methods of use employing such compounds and compositions.
    Type: Grant
    Filed: May 28, 1982
    Date of Patent: May 29, 1984
    Assignee: Monsanto Company
    Inventor: Gerhard H. Alt
  • Patent number: 4448986
    Abstract: (1R,cis)-Oxyimino-substituted cyclopropanecarboxylic acids are prepared via a (1R,4R,5S)-2-acetoxy-6,6-dimethyl-4-oxo-3-oxabicyclo[3.1.0]hexane intermediate.
    Type: Grant
    Filed: July 14, 1982
    Date of Patent: May 15, 1984
    Assignee: Shell Oil Company
    Inventor: Steven A. Roman
  • Patent number: 4440781
    Abstract: A method for producing a psychotropic response, especially for alleviating the symptoms of alcohol withdrawal, comprises administering to a human or animal subject in need thereof a psychotropically effective non-toxic amount of an oxyoctadecanoate. A composition for use in the present method is provided.
    Type: Grant
    Filed: June 11, 1982
    Date of Patent: April 3, 1984
    Assignee: The Vinoxen Company, Inc.
    Inventors: Herman P. Benecke, Bob E. Sherwood
  • Patent number: 4439442
    Abstract: The object of the invention is a new naftidrofuryl salt, naftidrofuryl citrate, which is therapeutically useful because it promotes metabolism and circulatory properties and because of its vaso-active properties in the treatment of arthritis of the limbs, Reynaud's Syndrome and cerebral circulatory insufficiency.
    Type: Grant
    Filed: May 14, 1982
    Date of Patent: March 27, 1984
    Assignee: SANOFI
    Inventors: Jacques A. Chick, Alain Heymes, Carlo Blasioli
  • Patent number: 4427685
    Abstract: Compounds of formula (I) and pharmaceutically acceptable salts thereof: ##STR1## wherein: a is 1 to 3;b is 0 to 2;c is 2 to 4;d is 1 to 5;X is sulphur, oxygen or --CH.sub.2 --;Y is oxygen, sulphur, NR.sub.4 or CHR.sub.5 wherein R.sub.4 is hydrogen, C.sub.1-4 alkyl, NO.sub.2 or CN, C.sub.1-4 alkylsulphonyl or phenylsulphonyl optionally substituted in the phenyl moiety by one or two substituents selected from C.sub.1-4 alkyl, C.sub.1-4 alkoxy, fluorine, chlorine or bromine, and R.sub.5 is NO.sub.2, C.sub.1-4 alkylsulphonyl or optionally substituted phenylsulphonyl as defined for R.sub.4 ;R.sub.1 and R.sub.2 are independently hydrogen, C.sub.1-4 alkyl, or C.sub.3-6 cycloalkyl; or R.sub.1 and R.sub.2 taken together with the nitrogen to which they are attached represent a pyrrolidino or piperidino ring;R.sub.6 and R.sub.7 are independently hydrogen or C.sub.
    Type: Grant
    Filed: February 3, 1982
    Date of Patent: January 24, 1984
    Assignee: Beecham Group P.L.C.
    Inventor: Geoffrey Stemp
  • Patent number: 4418202
    Abstract: Novel 2-vinyl(or ethyl)-1-cyanocyclopropane-1-carboxylates and 2-vinyl(or ethyl)-1-arylcyclopropane-1-carboxylates useful as herbicides, pesticides and chemical intermediates are provided. The invention also relates to a method of modifying plant growth by the application of vinyl(or ethyl)cyclopropane derivatives wherein the carboxylate group contains an amine or quaternized amine moiety.
    Type: Grant
    Filed: December 21, 1981
    Date of Patent: November 29, 1983
    Assignee: Emery Industries, Inc.
    Inventors: Richard G. Fayter, Jr., Allen L. Hall
  • Patent number: 4415743
    Abstract: Novel oxime ethers and oxime esters of the formula I given herein have various advantageous effects with regard to stimulation of plant growth, particularly in the early stage of development of the plant. Furthermore, such compounds have the property of rendering, in the sense of an antidote action, agricultural chemicals which would otherwise damage the plants (phytotoxic chemicals) more compatible with the cultivated plants. Herbicides that are insufficiently selective can be used for example in the presence of such oxime derivatives in specific cultivated crops for combating weeds, without disadvantageous consequences for the cultivated plants.
    Type: Grant
    Filed: September 30, 1982
    Date of Patent: November 15, 1983
    Assignee: Ciba-Geigy Corporation
    Inventor: Henry Martin
  • Patent number: 4411912
    Abstract: Esters and thiolesters of amino acids, intermediates therefor, synthesis thereof, and the use of said esters and thiolesters and compositions for the control of pests.
    Type: Grant
    Filed: November 13, 1979
    Date of Patent: October 25, 1983
    Assignee: Zoecon Corporation
    Inventors: Clive A. Henrick, Barbara A. Garcia
  • Patent number: 4411911
    Abstract: Novel sulfonate derivatives represented by the formulaR.sub.1 SO.sub.3 CH.sub.2 CO(CH.sub.2).sub.n R.sub.2act to inhibit esterases and chymotripsin and are useful as antilipemic agents, anti-inflammatory agents, immunity controlling agents, etc.
    Type: Grant
    Filed: January 19, 1981
    Date of Patent: October 25, 1983
    Assignee: Taiho Pharmaceutical Company, Limited
    Inventors: Setsuro Fujii, Toshihiro Hamakawa, Kazuo Ogawa, Yoshiyuki Muranaka, Sadao Hashimoto
  • Patent number: 4409398
    Abstract: (1R,cis)-Oxyimino-substituted cyclopropanecarboxylic acids are prepared via a (1R,4R,5S)-4-acetoxy-6,6-dimethyl-2-oxo-3-oxabicyclo [3.1.0]hexane intermediate.
    Type: Grant
    Filed: August 13, 1981
    Date of Patent: October 11, 1983
    Assignee: Shell Oil Company
    Inventor: Steven A. Roman
  • Patent number: 4407816
    Abstract: New derivatives of 3-furyl-, 3-thienyl- and 3-phenyl-2-propenimidamides are disclosed, which are useful as anti-ulcer agents. These new compounds are synthesized by reacting an imino ether derived from a corresponding 3-substituted-2-propenenitrile with a suitable amine.
    Type: Grant
    Filed: August 4, 1981
    Date of Patent: October 4, 1983
    Assignee: Kotobuki Seiyaku Company Limited
    Inventors: Tsuyoshi Tomiyama, Akira Tomiyama
  • Patent number: 4388469
    Abstract: Diphenylalkanoether and diphenylalkanone oxime-ether derivatives of the formula: ##STR1## wherein R.sup.1 and R.sup.2 are each independently an aryl group optionally substituted with 1 to 3 substituents selected from the group consisting of halogen, C.sub.1 -C.sub.4 alkyl, C.sub.1 -C.sub.4 alkoxy, nitro, cyano, di(C.sub.1 -C.sub.4)alkylamino, amino, benzyloxy, hydroxyl, C.sub.1 -C.sub.4 alkylthio, C.sub.1 -C.sub.4 alkylsulfinyl, C.sub.1 -C.sub.4 alkylsulfonyl, C.sub.1 -C.sub.4 alkanoylamino, C.sub.1 -C.sub.4 alkylamino and N-(C.sub.1 -C.sub.4)alkyl-N-(C.sub.1 -C.sub.4)alkanoylamino, Z.sup.1 is a group of the formula: ##STR2## (wherein R.sup.3 and R.sup.4 are each independently a hydrogen atom, a C.sub.1 -C.sub.4 alkyl group or an ar(C.sub.1 -C.sub.
    Type: Grant
    Filed: April 2, 1980
    Date of Patent: June 14, 1983
    Assignee: Sumitomo Chemical Company, Limited
    Inventors: Keiichi Ono, Hajime Kawakami, Junki Katsube
  • Patent number: 4382954
    Abstract: Compounds represented by the formula ##STR1## wherein R and R.sup.1 are independently hydrogen or lower alkyl; R.sup.2 is lower alkenyl, lower alkynyl or --CH.sub.2 X wherein X is halogen, hydroxyl, lower alkoxy, lower alkylthio or a furanyl ring; and Z is hydroxyl, lower alkoxy or --NR.sup.3 R.sup.4 wherein R.sup.3 and R.sup.4 are independently hydrogen or lower alkyl possess fungicidal activity. Moreover, some of the compounds of this invention also possess herbicidal activity.
    Type: Grant
    Filed: January 27, 1982
    Date of Patent: May 10, 1983
    Assignee: Chevron Research Company
    Inventor: David C. K. Chan
  • Patent number: 4372776
    Abstract: Compounds of the formula ##STR1## wherein R.sup.1 and R.sup.3 each is hydrogen or R.sup.1 and R.sup.3 together form a second carbon-to-nitrogen bond, R.sup.2 is hydrogen or cyano, R.sup.4 is alkyl and Ar is one of certain aromatic moieties.The compounds can be used as abscission agents for the loosening of fruit and/or leaves on plants.
    Type: Grant
    Filed: October 16, 1981
    Date of Patent: February 8, 1983
    Assignee: Shell Oil Company
    Inventors: Janet A. Day, Robert J. G. Searle
  • Patent number: 4370488
    Abstract: The invention includes novel alkali metal complex compounds (and processes for their preparation) which are useful, inter alia for the hydrogenation of alkali metals at room temperature or below room temperature to form hydrides or nitrides.
    Type: Grant
    Filed: June 18, 1981
    Date of Patent: January 25, 1983
    Assignee: Studiengesellschaft Kohle mbH
    Inventor: Borislav Bogdanovic
  • Patent number: 4370498
    Abstract: .alpha.-Ketocarboxylic acid N-acylamides of the formulaR.sup.1 --CO--CO--NH--CO--R.sup.2in whichR.sup.1 is an optionally substituted aliphatic radical with up to 12 carbon atoms, an optionally substituted cycloalkyl radical with 3 to 10 carbon atoms, an optionally substituted heterocyclic radical, andR.sup.2 is an optionally substituted aliphatic radical with up to 8 carbon atoms or an optionally substituted phenyl radical,are prepared by reacting an acyl cyanide of the formulaR.sup.1 --CO--CNwith a carboxylic acid anhydride of the formulaR.sup.2 --CO--O--CO--R.sup.2in the presence of a strong acid, and then adding water to the reaction mixture. The products can be used directly in the synthesis of known herbicides.
    Type: Grant
    Filed: February 19, 1981
    Date of Patent: January 25, 1983
    Assignee: Bayer Aktiengesellschaft
    Inventors: Gerhard Bonse, Heinz U. Blank
  • Patent number: 4349689
    Abstract: The present specification provides novel analogs of carbacyclin (CBA.sub.2), 6a-carba-prostacyclin (6a-carba-PGI.sub.2), which have pronounced prostacyclin-like pharmacological activity, e.g., as platelet anti-aggregatory agents. Specifically the novel chemical analogs of CBA.sub.2 are those substituted by fluoro (C-5), alkyl (C-9), interphenylene (C-5), and methano (C-6a,9). Further provided are benzindene analogs of CBA.sub.2 and substituted forms thereof, i.e., 9-deoxy-2',9-methano (or 2',9-metheno)-3-oxa-4,5,6-trinor-3,7-(1',3'-interphenylene)-PGF.sub.1 compounds. Also provided are a variety of novel chemical intermediates, e.g., substituted bicyclo[3.3.0]octane intermediates, and chemical process utilizing such intermediates which are useful in the preparation of the novel CBA.sub.2 analogs.
    Type: Grant
    Filed: December 22, 1980
    Date of Patent: September 14, 1982
    Assignee: The Upjohn Company
    Inventor: Paul A. Aristoff
  • Patent number: 4347372
    Abstract: A process for protecting cultivated plants against aggressive agricultural chemicals is described in which oxime derivatives of the formula ##STR1## are used as antidotes. Either the cultivated area for the cultivated plants or the cultivated plants themselves or parts of the plant (seeds, tubers, stem parts and the like), as desired, can be treated with these oxime derivatives, which are used as a dressing.
    Type: Grant
    Filed: August 28, 1979
    Date of Patent: August 31, 1982
    Assignee: Ciba-Geigy Corporation
    Inventors: Alfons Lukaszczyk, Henry Martin, Peter J. Diel, Werner Fory, Karl Gatzi, Haukur Kristinsson, Beat Muller, Rene Muntwyler, Johannes P. Pachlatko, Hermann Rempfler, Rolf Schurter, Henry Szczepanski
  • Patent number: 4344893
    Abstract: Novel compounds are described which are substituted benzophenone hydrazones. They have pesticidal activity, especially against insects and acarids, and pesticidal compositions and methods are described. Methods of making the compounds, and novel intermediates, are also described.
    Type: Grant
    Filed: February 25, 1980
    Date of Patent: August 17, 1982
    Assignee: The Boots Company Limited
    Inventors: Leonard G. Copping, John C. Kerry, Thomas I. Watkins, Robert J. Willis, Bryan H. Palmer
  • Patent number: 4339386
    Abstract: Compounds of the formula: ##STR1## wherein R is 4-chlorophenyl, 3,4-dichlorophenyl, or 3,4-dimethoxyphenyl, and R.sub.1 is hydrogen or methylaminocarbonyl with the proviso that when R is 4-chlorophenyl, R.sub.1 is methylaminocarbonyl are useful as antifungal agents.
    Type: Grant
    Filed: August 5, 1981
    Date of Patent: July 13, 1982
    Assignee: Morton-Norwich Products, Inc.
    Inventors: Robert J. Alaimo, Joseph E. Gray
  • Patent number: 4336199
    Abstract: The compound 5-(2,4-dichlorophenyl)-2-furancarboxaldehyde-O-[(methylamino)carbonyl]oxim e is useful as an antifungal agent.
    Type: Grant
    Filed: July 10, 1981
    Date of Patent: June 22, 1982
    Assignee: Morton-Norwich Products, Inc.
    Inventors: Robert J. Alaimo, Joseph E. Gray
  • Patent number: 4335138
    Abstract: Novel carbamates derived from substituted cyclic .beta.-keto-alcohols, their preparation, and pharmaceutical formulations which contain these compounds and which may be used as hypnotics in the treatment of sleep disturbance and as sedatives.
    Type: Grant
    Filed: September 15, 1980
    Date of Patent: June 15, 1982
    Assignee: BASF Aktiengesellschaft
    Inventors: Walter-Wielant Wiersdorff, Karl-Heinz Geiss, Harald Weifenbach, Wolfgang Worstmann, Dieter Lenke, Rolf Kretzschmar
  • Patent number: 4332952
    Abstract: Hypoglycemic 5-furyl and 5-thienyl derivatives of oxazolidine-2,4-dione and the pharmaceutically-acceptable salts thereof; certain 3-acylated derivatives thereof; and intermediates useful in the preparation of said compounds.
    Type: Grant
    Filed: April 23, 1981
    Date of Patent: June 1, 1982
    Assignee: Pfizer Inc.
    Inventor: Rodney C. Schnur
  • Patent number: 4332735
    Abstract: The compound 5-[3,4-dimethoxyphenyl]-N-{[(methylamino)carbonyl]oxy}-.alpha.-oxo-2-furan ethanimidoyl chloride is useful as an antifungal agent.
    Type: Grant
    Filed: July 6, 1981
    Date of Patent: June 1, 1982
    Assignee: Morton-Norwich Products, Inc.
    Inventors: Robert J. Alaimo, Joseph E. Gray, George M. Klein
  • Patent number: 4328237
    Abstract: Pyrethroid type insecticides are described having the formula: ##STR1## Compounds of general formula I are endowed with a high insecticide and acaricide activity.
    Type: Grant
    Filed: February 26, 1979
    Date of Patent: May 4, 1982
    Assignee: Montedison S.p.A.
    Inventors: Paolo Piccardi, Francesco Corda, Franco Gozzo, Augusto Menconi, Angelo Longoni