Polycyclo Ring System Having The Hetero Ring As One Of The Cyclos Patents (Class 549/543)
Tetracyclo ring system having the hetero ring as one of the cyclos (Class 549/544)
Tricyclo ring system having the hetero ring as one of the cyclos (Class 549/545)
Bicyclo ring system having the hetero ring as one of the cyclos (Class 549/546)
  • Synthesis of (+)-4-demethoxydaunomycinone
    Patent number: 4489206
    Abstract: It has been found that stereospecific R(-)-4-demethoxy-7-deoxydaunomycinone can be synthesized from the known compound 4-demethoxy-7,9-dideoxydaunomycinone. R(-)-4-Demethoxy-7-deoxy-daunomycinone is an intermediate in the synthesis of (+)-4-demethoxydaunomycinone, the aglycone of the nonnaturally occurring and antitumor active (-)7(S)9(S)-4-demethoxydaunorubicin.
    Type: Grant
    Filed: May 13, 1983
    Date of Patent: December 18, 1984
    Assignee: Adria Laboratories, Inc.
    Inventors: Michael P. Cava, Domingo Dominguez