Nitrogen Attached Indirectly To The Hetero Ring By Nonionic Bonding Patents (Class 549/551)
  • Patent number: 9957214
    Abstract: The invention provides a compound of formula (I): [insert formula (I)] wherein X, Y, and R1-R4 have any of the values defined in the specification, and salts thereof, as well as compositions comprising the compounds or salts. The compounds are useful for treating diseases associated with impaired mitochondrial function in an animal.
    Type: Grant
    Filed: October 10, 2013
    Date of Patent: May 1, 2018
    Assignee: ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY
    Inventors: Manikandadas Mathilakathu Madathil, Omar Khdour, Sidney Hecht
  • Patent number: 9789072
    Abstract: (RS)-[2-(3,4-dimethoxyphenyl)ethyl][2-hydroxy-3-(3-methylphenoxy)propyl]amine having the formula (IA), or a pharmaceutically acceptable salt thereof for the formulation of a pharmaceutical composition is useful for the prophylaxis and/or the treatment of hyperkinetic movement disorders associated with Huntington's disease, Wilson's disease, Tourette syndrome, restless leg syndrome, and tardive dyskinesia.
    Type: Grant
    Filed: June 18, 2014
    Date of Patent: October 17, 2017
    Assignee: SOM INNOVATION BIOTECH, S.L.
    Inventors: Nuria Gavalda Batalla, Raul Insa Boronat, Nuria Reig Bolano
  • Patent number: 9303114
    Abstract: The present invention discloses one liquid type cyanate ester-epoxy composite resin composition comprised of (A) cyanate ester resin, (B) epoxy resin and (C) latent curing agent. The present one liquid type cyanate ester-epoxy composite resin composition is characterized in that the above (C) latent curing agent is comprised of a modified amine (a), which has one or more amino group having active hydrogen within a molecule, obtained by a reaction of a polyamine compound (a-1) with an epoxy compound (a-2), and a phenol resin (b), and that the above polyamine compound (a-1) is a polyether polyamine compound and/or the above epoxy compound (a-2) is a polyether polyepoxy compound.
    Type: Grant
    Filed: November 19, 2009
    Date of Patent: April 5, 2016
    Assignee: ADEKA CORPORATION
    Inventors: Ryo Ogawa, Shinsuke Yamada
  • Patent number: 9151743
    Abstract: The invention relates to a method for screening compounds, which inhibit MetAP2 activity, by providing a cellular system or a sample thereof being capable of expressing MetAP2 and/or EEF1A, incubating at least a portion of the system with compounds to be screened, and detecting MetAP2 inhibition by determining EEF1A with N-terminal methionine residue (MetEEF1A). Another object of the invention concerns a method for monitoring physiological and/or pathological conditions, which are caused, mediated and/or propagated by MetAP2 activity, by administering an effective amount of at least a single compound to a mammal in need of such treatment and determining MetEEF1A in a biological sample withdrawn from the mammal. The invention also relates to the use of EEF1A as biomarker.
    Type: Grant
    Filed: October 5, 2009
    Date of Patent: October 6, 2015
    Assignee: MERCK PATENT GMBH
    Inventors: Roland Kellner, Frank Zenke, Joerg Bomke
  • Patent number: 9035078
    Abstract: The invention relates to novel nitrile compounds according to formula I and II: (I) Formula I wherein: X=—CH3 or —C?N, (II) Formula II wherein: X=—CH3 or —C?N, each Y is independently chosen from —OH or RC(0)0-, each R is independently chosen from a C1-21 alkyl group. The invention also relates to processes for the preparation of nitrile compounds according to formula I and II and to uses of the nitrile compounds.
    Type: Grant
    Filed: July 6, 2012
    Date of Patent: May 19, 2015
    Assignee: DSM IP ASSETS B.V.
    Inventors: Paulus Lambertus Alsters, Edwin Gerard Ijpeij
  • Publication number: 20150111994
    Abstract: Provided is an epoxy-amine adduct that offers high reactivity, contributes to better adhesion between a resin and a reinforcing fiber in a fiber-reinforced composite material, and can be easily blended with another component such as a resin. The epoxy-amine adduct has two or more amino groups per molecule and is obtained by a reaction of an epoxy compound (A) having two or more alicyclic epoxy groups per molecule with an amine compound (B) having two or more amino groups per molecule.
    Type: Application
    Filed: April 30, 2013
    Publication date: April 23, 2015
    Inventor: Masanori Sakane
  • Publication number: 20150111964
    Abstract: The disclosure is in part directed to crystalline forms of an oxalate salt of 6-O-(4-dimethylaminoethoxy)cinnamoyl fumagillol.
    Type: Application
    Filed: May 7, 2013
    Publication date: April 23, 2015
    Applicant: ZAFGEN, INC.
    Inventor: Thomas Crawford
  • Patent number: 9000071
    Abstract: An epoxy resin compound including an epoxy resin, a hardening agent, and an inorganic filler as a main component is provided. The epoxy resin includes an epoxy resin represented by a chemical formula. Therefore, the epoxy resin having a mesogen structure that increases crystallinity is used, and thus thermal conductivity can be increased. Further, the epoxy resin is used as an insulating material for a printed circuit board, and thus a high radiant heat substrate can be provided.
    Type: Grant
    Filed: April 29, 2013
    Date of Patent: April 7, 2015
    Assignee: LG Innotek Co., Ltd.
    Inventors: Jae Man Park, Hae Yeon Kim, SungBae Moon, Jeungook Park, SungJin Yun, JongHeum Yoon, Hyuk Soo Lee, Jaehun Jeong, In Hee Cho
  • Publication number: 20140213804
    Abstract: The invention relates to novel nitrile compounds according to formula I and II: (I) Formula I wherein: X=—CH3 or —C?N, (II) Formula II wherein: X=—CH3 or —C?N, each Y is independently chosen from —OH or RC(O)O—, each R is independently chosen from a C1?21 alkyl group. The invention also relates to processes for the preparation of nitrile compounds according to formula I and II and to uses of the nitrile compounds.
    Type: Application
    Filed: July 6, 2012
    Publication date: July 31, 2014
    Applicant: DSM IP ASSETS B.V.
    Inventors: Paulus Lambertus Alsters, Edwin Gerard Ijpeij
  • Patent number: 8735447
    Abstract: The disclosure is in part directed to crystalline forms of 6-O-(4-dimethylaminoethoxy)cinnamoyl fumagillol and variants thereof.
    Type: Grant
    Filed: November 16, 2012
    Date of Patent: May 27, 2014
    Assignee: Zafgen, Inc.
    Inventors: Thomas Crawford, Hayley A. Reece
  • Publication number: 20140066408
    Abstract: This invention provides, but is not limited to, novel oleanolic acid derivatives having the formula: wherein the variables are defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such compounds, methods and intermediates useful for making the compounds, and methods of using the compounds and compositions.
    Type: Application
    Filed: January 14, 2013
    Publication date: March 6, 2014
    Applicant: REATA PHARMACEUTICALS, INC.
    Inventor: REATA PHARMACEUTICALS, INC.
  • Patent number: 8664413
    Abstract: An epoxy compound of high-purity N,N,N?,N?-tetraglycidyl-3,4?-diaminodiphenyl ether is produced by: an addition reaction step of reacting 3,4?-diaminodiphenyl ether with epichlorohydrin in a polar protic solvent at 65 to 100° C. for 12 hours or longer to form N,N,N?,N?-tetrakis(3-chloro-2-hydroxypropyl)-3,4?-diaminodiphenyl ether; and a cyclization reaction step of reacting the N,N,N?,N?-tetrakis(3-chloro-2-hydroxypropyl)-3,4?-diaminodiphenyl ether with an alkali compound for dehydrochlorination.
    Type: Grant
    Filed: March 2, 2011
    Date of Patent: March 4, 2014
    Assignee: Toray Fine Chemicals Co., Ltd.
    Inventors: Michiya Ishikawa, Hidetoshi Kato, Jiro Nakatani, Atsuhito Arai, Hiroaki Sakata, Hiroshi Taiko
  • Publication number: 20140016179
    Abstract: A compound is disclosed. The compound has a general structure: wherein R1, R2, and R3 are each independently selected from the group consisting of hydrogen, substituted saturated hydrocarbons, non-substituted saturated hydrocarbons, substituted unsaturated hydrocarbons, and non-substituted unsaturated hydrocarbons; wherein E and D are each independently selected from the group consisting of CH2, O, S, and NH; and wherein a, b, x, y, and z are each independently any whole number between 0 and 45, inclusive, wherein the sum of a and b is less than 45 or equal to 45 and wherein the sum of x, y, and z is less than 45 or equal to 45.
    Type: Application
    Filed: July 12, 2012
    Publication date: January 16, 2014
    Inventors: Zhang-Lin Zhou, Qin Liu
  • Publication number: 20130333121
    Abstract: Mixtures are described which contain reaction products of one or more amines with one or more epoxides and additionally isocyanates. Applying such mixtures to textile fabrics, especially polyester fiber fabrics, reduces or prevents unpleasant sweaty odor after physical exercise. The effects are very durable to laundering.
    Type: Application
    Filed: February 29, 2012
    Publication date: December 19, 2013
    Applicant: Huntsman Textile Effects (Germany) GmbH
    Inventors: Alfred Weihrather, Gunter Presnitz, Reinhold Braun
  • Publication number: 20130309324
    Abstract: The present invention provides O-nitro compounds, pharmaceutical compositions of O-nitro compounds and methods of using O-nitro compounds and/or pharmaceutical compositions thereof to treat or prevent diseases or disorders characterized by abnormal cell proliferation, such as cancer, inflammation, cardiovascular disease and autoimmune disease.
    Type: Application
    Filed: July 26, 2013
    Publication date: November 21, 2013
    Applicants: RadioRx, Inc., c/o Interwest Venture Partners, Alliant Techsystems Inc.
    Inventors: Mark D. Bednarski, Susan Knox, Louis F. Cannizzo, Kristin F. Warner, Robert B. Wardle, Stephen P. Velarde, Shoucheng Ning
  • Publication number: 20130296455
    Abstract: Disclosed are a dye that is excellent in solubility and heat-resistance, and a novel compound that is suitable for the dye, and specifically provides a yellow dye having a maximum absorption wavelength in the region of 420 to 470 nm. Also disclosed are a colored (alkali-developable) photosensitive composition and an optical filter using the dye, and specifically provides a color filter that does not decrease luminance and thus is preferable for an image display device such as a liquid crystal display panel. Specifically, disclosed are a novel compound represented by the following general formula (1), a dye using the compound, and a colored (alkali-developable) photosensitive composition and a color filter. The content of the above-mentioned general formula (1) is as described in the description.
    Type: Application
    Filed: December 27, 2011
    Publication date: November 7, 2013
    Applicant: ADEKA CORPORATION
    Inventors: Yosuke Maeda, Masaaki Shimizu, Koichi Shigeno
  • Publication number: 20130284502
    Abstract: An epoxy resin compound including an epoxy resin, a hardening agent, and an inorganic filler as a main component is provided. The epoxy resin includes an epoxy resin represented by a chemical formula. Therefore, the epoxy resin having a mesogen structure that increases crystallinity is used, and thus thermal conductivity can be increased. Further, the epoxy resin is used as an insulating material for a printed circuit board, and thus a high radiant heat substrate can be provided.
    Type: Application
    Filed: April 29, 2013
    Publication date: October 31, 2013
    Applicant: LG INNOTEK CO., LTD.
    Inventors: Jae Man PARK, Hae Yeon KIM, SungBae MOON, Jeungook PARK, SungJin YUN, JongHeum YOON, Hyuk Soo LEE, Jaehun JEONG, In Hee CHO
  • Publication number: 20130172180
    Abstract: The present invention further relates to a process to make a superabsorbent polymer comprising the steps of a) preparing a neutralized monomer solution comprising a polymerizable monomer selected from unsaturated acid groups-containing monomers, ethylenically unsaturated carboxylic acid anhydride, salts, or derivatives thereof and a caustic agent selection from an alkali agent, wherein the polymerizable monomer is neutralized to from about 50 mol % to about 85 mol %; b) forming a crosslinker monomer mixture by adding an internal crosslinker composition to the neutralized monomer solution wherein the internal crosslinking composition is the reaction product of a stoichiometric excess of amine with a glycidyl compound, wherein the internal crosslinker composition has a residual amount of glycidyl compounds of less than about 500 ppm based on the mass of the internal crosslinker composition; and c) polymerizing the crosslinker monomer mixture to make a superabsorbent polymer.
    Type: Application
    Filed: February 28, 2013
    Publication date: July 4, 2013
    Applicant: EVONIK STOCKHAUSEN, LLC
    Inventor: Evonik Stockhausen, LLC
  • Publication number: 20130150290
    Abstract: The invention relates to crystalline peptide keto epoxide compounds, methods of their preparation, and related pharmaceutical compositions. This invention also relates to methods for the preparation of amino acid keto-epoxides. Specifically, allylic ketones are stereoselectively converted to the desired keto epoxides.
    Type: Application
    Filed: February 1, 2013
    Publication date: June 13, 2013
    Applicant: Onyx Therapeutics, Inc.
    Inventor: Onyx Therapeutics, Inc.
  • Patent number: 8445706
    Abstract: An unnatural amino acid including a phosphate mimicking group for mimicking a phosphate group in phosphoamino acids and a protein phosphatase modifying group for covalently binding protein phosphatases. A probe for detecting disease including a phosphate mimicking group for mimicking a phosphate group in phosphoamino acids and a protein phosphatase modifying group for covalently binding protein phosphatases. A method for detecting the presence of disease by administering the unnatural amino acid, binding the unnatural amino acid with a phosphatase, detecting a signal, and detecting the presence of disease. A method of identifying a known protein phosphatase, and a method of identifying an unknown protein phosphatase. A method of making the unnatural amino acid.
    Type: Grant
    Filed: September 1, 2009
    Date of Patent: May 21, 2013
    Assignee: Board of Trustees of Northern Illinois University
    Inventor: Kui Shen
  • Publication number: 20130046067
    Abstract: The present disclosure provides for polycyclopentadiene compounds that useful as an epoxide resin and/or as an adduct for a curable composition.
    Type: Application
    Filed: April 21, 2011
    Publication date: February 21, 2013
    Applicant: DOW GLOBAL TECHNOLOGIES LLC
    Inventors: Robert E. Hefner, JR., Michael J. Mullins
  • Publication number: 20130012730
    Abstract: An epoxy compound of high-purity N,N,N?,N?-tetraglycidyl-3,4?-diaminodiphenyl ether is produced by: an addition reaction step of reacting 3,4?-diaminodiphenyl ether with epichloro-hydrin in a polar protic solvent at 65 to 100° C. for 12 hours or longer to form N,N,N?,N?-tetrakis(3-chloro-2-hydroxypropyl)-3,4?-diaminodiphenyl ether; and a cyclization reaction step of reacting the N,N,N?,N?-tetrakis(3-chloro-2-hydroxypropyl)-3,4?-diaminodiphenyl ether with an alkali compound for dehydrochlorination.
    Type: Application
    Filed: March 2, 2011
    Publication date: January 10, 2013
    Applicant: TORAY FINE CHEMICALS CO., LTD.
    Inventors: Michiya Ishikawa, Hidetoshi Kato, Jiro Nakatani, Atsuhito Arai, Hiroaki Sakata, Hiroshi Taiko
  • Patent number: 8349891
    Abstract: The disclosure is in part directed to crystalline forms of 6-O-(4-dimethylaminoethoxy)cinnamoyl fumagillol and variants thereof.
    Type: Grant
    Filed: August 7, 2012
    Date of Patent: January 8, 2013
    Assignee: Zafgen, Inc.
    Inventors: Thomas Crawford, Hayley A. Reece
  • Patent number: 8324340
    Abstract: A one-component, moisture curing composition that has a) at least one polyurethane polymer P1, being liquid at room temperature and having isocyanate groups and b) at least one polyurethane polymer A of the formula (Ia) or (Ib), being solid at room temperature and having aldimine groups with a melting point in the range from 40° C. to 80° C., the composition 1) being capable of being applied warm; 2) having adjustable cure times and a good initial strength with suitable application properties; 3) curing under the influence of humidity without bubbles; and 4) having a good elasticity and mechanical rigidity after curing.
    Type: Grant
    Filed: October 31, 2007
    Date of Patent: December 4, 2012
    Assignee: Sika Technology AG
    Inventors: Urs Burckhardt, Michael Schlumpf
  • Patent number: 8318959
    Abstract: The method of preparing novel allyl ethers. Novel glycidyl ethers and their preparation. Polyfunctional poly(glycidyl ethers) their methods of preparation. Novel polyurethanes based on the polyfunctional glycidyl ethers and their method of preparation.
    Type: Grant
    Filed: January 4, 2012
    Date of Patent: November 27, 2012
    Assignee: Flurochem, Inc.
    Inventors: Kurt Baum, Wen-Huey Lin
  • Publication number: 20120196923
    Abstract: Disclosed herein are polymers that can be made cationic and used to deliver a substance into a cell. Also disclosed are pharmaceutical compositions comprising the polymers and methods of using the polymers.
    Type: Application
    Filed: May 17, 2010
    Publication date: August 2, 2012
    Inventors: Kaushal Rege, Ravindra S. Kane, Steven M. Cramer, Sutapa Barua
  • Patent number: 8097741
    Abstract: The invention relates to solvent-containing two-component polyurethane moisture cured hybrid sol-gel coating formulation comprising 1) an epoxy-functional binder with carbamate functionality and 2) a blended curing component comprising at least one sol gel precursor and an amine crosslinker.
    Type: Grant
    Filed: March 31, 2008
    Date of Patent: January 17, 2012
    Assignee: NDSU Research Foundation
    Inventors: Dean C. Webster, Dipak Chattopadhyay
  • Publication number: 20110301347
    Abstract: The present invention relates to the compounds of formula I, processes for their production and their use as anti-inflammatory agents.
    Type: Application
    Filed: August 15, 2011
    Publication date: December 8, 2011
    Inventors: Markus BERGER, Jan Dahmen, Hartmut Rehwinkel, Stefan Jaroch, Heike Schäcke
  • Patent number: 8039537
    Abstract: A modified bismaleimide resin of Formula (I) or (II) is provided. In Formula (I) or (II), Q is —CH2—, —C(CH3)2—, —O—, —S—, —SO2— or null, R is —(CH2)2—, —(CH2)6—, —(CH2)8—, —(CH2)12—, —CH2—C(CH3)2—CH2—CH(CH3)—CH2—CH2—, 10<n<500, and x+y=n. The invention also provides a method for preparing a modified bismaleimide resin and a composition including the modified bismaleimide resin.
    Type: Grant
    Filed: February 22, 2010
    Date of Patent: October 18, 2011
    Assignee: Industrial Technology Research Institute
    Inventors: Feng-Po Tseng, Lu-Shih Liao, Kuo-Chan Chiou
  • Publication number: 20110190302
    Abstract: The present invention pertains generally to the field of therapeutic compounds, and more specifically to certain aryl-phenyl-sulfonamido-phenylene compounds of the following formula (I) (collectively referred to herein as “APSAP compounds”).
    Type: Application
    Filed: September 18, 2009
    Publication date: August 4, 2011
    Applicant: PIMCO 2664 LIMITED
    Inventors: Iain Robert Greig, Rose Mary Sheridan, Raymond Fisher, Matthew John Tozer, Juha Andrew Clase, Andrew Smith, Andrew Robert Tuffnell, Robert Jurgen Van 't Hof
  • Publication number: 20110146536
    Abstract: Provided are aminoalcohol compounds for use as neutralizing agents for paints and coatings. The compounds are of the formula (I): or salt thereof, wherein R1, R2, R3, R4, R5, and n are as defined herein. Also provided are precursors of the aminoalcohol compounds and processes for making and using them.
    Type: Application
    Filed: December 1, 2010
    Publication date: June 23, 2011
    Inventors: Ian A. Tomlinson, Asghar A. Peera, George D. Green
  • Publication number: 20110142947
    Abstract: Nanoparticles comprising T3 and their use in treating, e.g., cardiac conditions, for example cardiac arrest, are provided. Such nanoparticles provide improved delivery of T3 and allow for acute treatment and optionally for sustained release of T3 in a patient.
    Type: Application
    Filed: June 8, 2010
    Publication date: June 16, 2011
    Inventors: Leo Rubin, Shaker Mousa
  • Patent number: 7931946
    Abstract: Disclosed are a novel liquid crystal compound containing a sulfone group, a liquid crystal composition comprising the same, and an optical film using the same liquid crystal composition. More particularly, there are provided a liquid crystal material for a viewing angle compensation film with high quality characteristics, which can improve a contrast ratio measured at a tilt angle to the front and minimize variations in color with viewing angles in a black state, a liquid crystal composition comprising the same liquid crystal material, and a compensation film obtained from the same liquid crystal composition.
    Type: Grant
    Filed: January 22, 2008
    Date of Patent: April 26, 2011
    Assignee: LG Chem, Ltd.
    Inventors: Jae-Ho Cheong, Min-Jin Ko, Myung-Sun Moon, Bum-Gyu Choi, Dae-Ho Kang, Ki-Youl Lee, Yun-Bong Kim
  • Publication number: 20110065612
    Abstract: The invention relates to a class of novel surfactants that have utility in the recovery and/or extraction of oil.
    Type: Application
    Filed: December 10, 2009
    Publication date: March 17, 2011
    Inventors: Kristoffer K. Stokes, Michael C. Berg, David Soane, Kevin T. Petersen, John H. Dise, Atul C. Thakrar, Rosa Casado
  • Publication number: 20110040111
    Abstract: A novel epoxy compound represented by the following formula and a method for producing the same are provided: wherein R1 and R2 are members selected from the group consisting of hydrogen, aliphatic hydrocarbon group having 1 to 4 carbon atoms, alicyclic hydrocarbon group having 3 to 6 carbon atoms, aromatic hydrocarbon group having 6 to 10 carbon atoms, halogen atom, ether group, ester group, acyl group and nitro group, n is an integer of 1 to 4, and m is an integer of 1 to 5.
    Type: Application
    Filed: October 13, 2009
    Publication date: February 17, 2011
    Applicant: Toray Fine Chemicals Co., Ltd.
    Inventors: Koutaro Ono, Michiya Ishikawa, Jiro Nakatani
  • Patent number: 7880023
    Abstract: A synthesis of an energetic prepolymer used as a high-energy binder for an insensitive and high performance explosive is disclosed. More specifically, provided are a novel compound 2-nitratoethyl oxirane expressed by formula III, a novel compound poly(2-nitratoethyl oxirane) expressed by formula IV, obtained by polymerization of 2-nitratoethyl oxirane used as a monomer and a preparation method thereof. The compound, used as an energetic prepolymer and a monomer for preparation thereof can substitute for existing poly(glycidyl nitrate) (PGN) which has been known to be a promising one having the best performance among existing energetic prepolymers, but which has a problem to be self-decomposed after synthesis of polyurethane elastomer, to solve this problem.
    Type: Grant
    Filed: April 28, 2009
    Date of Patent: February 1, 2011
    Assignee: Agency for Defense Development A Non Profit Korean Organization
    Inventors: Jin Seuk Kim, Jin Rai Cho, Keun Deuk Lee, Jeong-Kook Kim
  • Publication number: 20100311581
    Abstract: The present invention relates to triazolylmethyloxiranes of the formula I in which the variables D and B have the meanings as defined in the description and the claims.
    Type: Application
    Filed: December 15, 2008
    Publication date: December 9, 2010
    Applicant: BASF SE
    Inventors: Jochen Dietz, Thomas Grote, Bernd Mueller, Jan Klaas Lohmann, Jens Renner, Sarah Ulmschneider, Alice Glaettli, Marianna Vrettou
  • Patent number: 7718695
    Abstract: The present invention relates to an inclusion compound of fumagillol derivative or its salt with hydroxypropyl-?-cyclodextrin or sulfobutylether-7-?-cyclodextrin, and pharmaceutical compositions comprising the same. The inclusion compound according to the present invention has superior water solubility and stability while exhibiting low toxicity, rendering it valuable as an anticancer agent or inhibitor of tumor metastasis.
    Type: Grant
    Filed: July 25, 2007
    Date of Patent: May 18, 2010
    Assignee: Chong Kun Dang Pharmaceutical Corp.
    Inventors: Jae Hyun Kim, Su Kyung Lee, Won Kyu Choi, Jong Lae Lim, Soon Kil Ahn, Hee Jong Shin, Chung Il Hong
  • Publication number: 20100096590
    Abstract: Disclosed are a novel liquid crystal compound containing a sulfone group, a liquid crystal composition comprising the same, and an optical film using the same liquid crystal composition. More particularly, there are provided a liquid crystal material for a viewing angle compensation film with high quality characteristics, which can improve a contrast ratio measured at a tilt angle to the front and minimize variations in color with viewing angles in a black state, a liquid crystal composition comprising the same liquid crystal material, and a compensation film obtained from the same liquid crystal composition.
    Type: Application
    Filed: January 22, 2008
    Publication date: April 22, 2010
    Inventors: Jae-Ho Cheong, Min-Jin Ko, Myung-Sun Moon, Bum-Gyu Choi, Dae-Ho Kang, Ki-Youl Lee, Yun-Bong Kim
  • Patent number: 7629433
    Abstract: The invention relates to compounds of formula (I) which contain aldimine, and to the use thereof. Said compounds which contain aldimines are characterized in that they are odor-less and during hydrolysis the odor-free aldehydes are separated. They are used, therefor, as sources for aldehydes. They can also be used in cross-linking reactions.
    Type: Grant
    Filed: September 29, 2006
    Date of Patent: December 8, 2009
    Assignee: Sika Technology AG
    Inventor: Urs Burckhardt
  • Publication number: 20090275765
    Abstract: A synthesis of an energetic prepolymer used as a high-energy binder for an insensitive and high performance explosive is disclosed. More specifically, provided are a novel compound 2-nitratoethyl oxirane expressed by formula III, a novel compound poly(2-nitratoethyl oxirane) expressed by formula IV, obtained by polymerization of 2-nitratoethyl oxirane used as a monomer and a preparation method thereof. The compound, used as an energetic prepolymer and a monomer for preparation thereof can substitute for existing poly(glycidyl nitrate) (PGN) which has been known to be a promising one having the best performance among existing energetic prepolymers, but which has a problem to be self-decomposed after synthesis of polyurethane elastomer, to solve this problem.
    Type: Application
    Filed: April 28, 2009
    Publication date: November 5, 2009
    Inventors: Jin Seuk Kim, Jin Rai Cho, Keun Deuk Lee, Jeong-Kook Kim
  • Patent number: 7534540
    Abstract: An improved organophotoreceptor comprises an electrically conductive substrate and a photoconductive element on the electrically conductive substrate, the photoconductive element comprising: (a) a charge transport material having the formula where X and X? are, each independently, a linking group; Ar comprises an aromatic group; R1, R2, and R3 comprise, each independently, H, an alkyl group, an alkenyl group, an alkynyl group, an aromatic group, or a heterocyclic group; and E1 and E2 are, each independently, a reactive ring group; and (b) a charge generating compound. Corresponding electrophotographic apparatuses, imaging methods, and a polymeric charge transport material prepared from the charge transport material above are described.
    Type: Grant
    Filed: April 29, 2004
    Date of Patent: May 19, 2009
    Assignee: Samsung Electronics Co., Ltd.
    Inventors: Zbigniew Tokarski, Nusrallah Jubran, Vytautas Getautis, Vygintas Jankauskas, Tadas Malinauskas, Edmundas Montrimas
  • Publication number: 20090099333
    Abstract: The invention relates to compounds of formula (I) which contain aldimine, and to the use thereof. Said compounds which contain aldimines are characterised in that they are odour-less and during hydrolysis the odour-free aldehydes are separated. They are used, therefor, as sources for aldehydes. They can also be used in cross-linking reactions.
    Type: Application
    Filed: September 29, 2006
    Publication date: April 16, 2009
    Applicant: SIKA TECHNOLOGY AG
    Inventor: Urs Burckhardt
  • Publication number: 20080312440
    Abstract: The present invention relates to drug derivatives and linkers. The invention specifically relates to compounds and methods of phosphonates and linkers, that are useful as carriers for imaging agents and useful in the treatment of various bone diseases.
    Type: Application
    Filed: April 16, 2008
    Publication date: December 18, 2008
    Applicant: University of Southern California
    Inventors: Charles E. McKenna, Boris A. Kashemirov, Joy Lynn F. Bala
  • Publication number: 20080312404
    Abstract: The present invention relates to novel diepoxides having the formulas I. and II. R*SO2N(A)RN(A)SO2R* where A=2,3-epoxypropyl, R* is a monovalent hydrocarbon radical or an inertly substituted hydrocarbon radical and R is a divalent hydrocarbon radical or an inertly substituted divalent hydrocarbon radical. The epoxies are useful in preparing novel epoxide resins.
    Type: Application
    Filed: August 14, 2008
    Publication date: December 18, 2008
    Inventor: R. Garth Pews
  • Patent number: 7427687
    Abstract: Disclosed are novel compounds that can be used as an energetic binder used for improving the performance and the properties of a high explosive, and a preparation method thereof. More specifically, provided are glycidyl dinitropropyl formal of chemical formula IV having a nitro group (—NO2) as an energy group and having no hydrogen bonding to carbon to which the nitro group is binding, poly(glycidyl dinitropropyl formal) of chemical formula V polymerized using the glycidyl dinitropropyl formal as a monomer, and a preparation method thereof.
    Type: Grant
    Filed: March 6, 2007
    Date of Patent: September 23, 2008
    Assignee: Agency for Defense Development
    Inventors: Jin Seuk Kim, Jin Rai Cho, Keun Deuk Lee, Jae Kyoung Kim
  • Publication number: 20080194852
    Abstract: A synthesis of an energetic prepolymer used as a high-energy binder for an insensitive and high performance explosive is disclosed. More specifically, provided are a novel compound 2-nitratoethyl oxirane expressed by formula III, a novel compound poly(2-nitratoethyl oxirane) expressed by formula IV, obtained by polymerization of 2-nitratoethyl oxirane used as a monomer and a preparation method thereof. The compound, used as an energetic prepolymer and a monomer for preparation thereof can substitute for existing poly(glycidyl nitrate) (PGN) which has been known to be a promising one having the best performance among existing energetic prepolymers, but which has a problem to be self-decomposed after synthesis of polyurethane elastomer, to solve this problem.
    Type: Application
    Filed: July 12, 2007
    Publication date: August 14, 2008
    Inventors: Jin Seuk Kim, Jin Rai Cho, Keun Deuk Lee, Jeong-Kook Kim
  • Publication number: 20080193988
    Abstract: The invention relates to a process for the preparation of compounds of formula (I) wherein Q1 is a group selected from formulae (II) & (III) and a group *-NR6-Q2-A or, if appropriate, their pharmaceutically acceptable salts and/or isomers, tautomers, solvates or isotopic variations thereof, as well as intermediates used in said process.
    Type: Application
    Filed: July 10, 2006
    Publication date: August 14, 2008
    Inventors: Iain Robert Gladwell, Pieter David De Koning, Ian Brian Moses, Alan John Pettman, Nicholas Murray Thomson
  • Publication number: 20080064884
    Abstract: The present invention relates to a novel process for the preparation of compounds of formula (I) wherein X, Q, R1 and R2 are as defined in the specification, the compounds being useful in the preparation of therapeutic agents. The invention further relates to novel intermediates useful in the preparation of the therapeutic agents.
    Type: Application
    Filed: May 3, 2007
    Publication date: March 13, 2008
    Applicant: AstraZeneca AB
    Inventors: Debra Ainge, Philip Cornwall, Duncan Michael Gill, Vinod Kumar, Luis Manuel Vaz, Philip O'Keefe, Rhona Sinclair, Edward Laurence Way
  • Publication number: 20080064659
    Abstract: An efficient new route for the preparation of dihydroeponemycin, an active eponemycin derivative, is provided, which includes the synthesis of the intermediate compound, a hydroxymethyl-substituted enone. In addition, a method is provided for synthesizing inhibitors, which includes PI?-modified analogues. These analogues selectively bind to a major immunoproteasome catalytic subunit LMP2 and inactivate its proteolytic activity in a method of treating diseases, including myeloma and other cancers, Huntington's disease and Alzheimer's disease.
    Type: Application
    Filed: September 12, 2006
    Publication date: March 13, 2008
    Inventors: Kyung Bo Kim, Yik Khuan Ho