Chalcogen And The Hetero Ring Bonded Directly To The Same Carbon (e.g., Glycidyl Ethers, Etc.) Patents (Class 549/555)
  • Patent number: 8921585
    Abstract: The present invention provides an efficient method of synthesizing and purifying dianhydrohexitols such as dianhydrogalactitol. In general, as applied to dianhydrogalactitol, the method comprises: (1) reacting dulcitol with a concentrated solution of hydrobromic acid at a temperature of about 80° C. to produce dibromogalactitol; (2) reacting the dibromogalactitol with potassium carbonate in t-butanol to produce dianhydrogalactitol; and (3) purifying the dianhydrogalactitol using a slurry of ethyl ether to produce purified dianhydrogalactitol. Another method produces dianhydrogalactitol from dulcitol; this method comprises: (1) reacting dulcitol with a reactant to convert the 1,6-hydroxy groups of dulcitol to an effective leaving group to generate an intermediate; and (2) reacting the intermediate with an inorganic weak base to produce dianhydrogalactitol through an intramolecular SN2 reaction. Other methods for the synthesis of dianhydrogalactitol from dulcitol are described.
    Type: Grant
    Filed: July 2, 2013
    Date of Patent: December 30, 2014
    Assignee: Del Mar Pharmaceuticals
    Inventor: Dennis M. Brown
  • Publication number: 20140016179
    Abstract: A compound is disclosed. The compound has a general structure: wherein R1, R2, and R3 are each independently selected from the group consisting of hydrogen, substituted saturated hydrocarbons, non-substituted saturated hydrocarbons, substituted unsaturated hydrocarbons, and non-substituted unsaturated hydrocarbons; wherein E and D are each independently selected from the group consisting of CH2, O, S, and NH; and wherein a, b, x, y, and z are each independently any whole number between 0 and 45, inclusive, wherein the sum of a and b is less than 45 or equal to 45 and wherein the sum of x, y, and z is less than 45 or equal to 45.
    Type: Application
    Filed: July 12, 2012
    Publication date: January 16, 2014
    Inventors: Zhang-Lin Zhou, Qin Liu
  • Patent number: 8563758
    Abstract: The present invention provides an efficient method of synthesizing and purifying dianhydrohexitols such as dianhydrogalactitol. In general, as applied to dianhydrogalactitol, the method comprises: (1) reacting dulcitol with a concentrated solution of hydrobromic acid at a temperature of about 80° C. to produce dibromogalactitol; (2) reacting the dibromogalactitol with potassium carbonate in t-butanol to produce dianhydrogalactitol; and (3) purifying the dianhydrogalactitol using a slurry of ethyl ether to produce purified dianhydrogalactitol.
    Type: Grant
    Filed: August 17, 2011
    Date of Patent: October 22, 2013
    Assignee: Del Mar Pharmaceuticals
    Inventor: Dennis M. Brown
  • Patent number: 8383317
    Abstract: Disclosed herein are methods of making a negative pattern of carbon nanotubes or a polymerized carbon nanotube composite having an interpenetrating polymer network (IPN) by modifying the surfaces of the carbon nanotubes with polymerizable functional groups such as oxirane and anhydride groups and subjecting the surface-modified carbon nanotubes either to a photolithography process or to a heatcuring process. By virtue of the present invention, desired patterns of carbon nanotubes can be easily made on the surfaces of various substrates, and polymerized carbon nanotube composites improved in hardening properties can be made without additional polymers.
    Type: Grant
    Filed: May 9, 2007
    Date of Patent: February 26, 2013
    Assignee: Samsung Electronics Co., Ltd.
    Inventors: Jong Jin Park, Jung Han Shin, Sang Yoon Lee
  • Patent number: 8372994
    Abstract: Glycidyl 2-propylheptanoate, glycidyl 4-methyl-2-propylhexanoate or a mixture of these (referred to collectively for short as glycidyl ester).
    Type: Grant
    Filed: June 24, 2008
    Date of Patent: February 12, 2013
    Assignee: BASF SE
    Inventors: Kai Gumlich, Roland Merten, Michael Henningsen, Martin Schaefer, Joaquim Henrique Teles, Bernhard Mohr
  • Publication number: 20120238717
    Abstract: A composition is provided that contains an intermediate for a water-soluble monomer, wherein this intermediate is suitable for producing a water-soluble polyalkylene glycol-type monomer that has a polymerizable terminal double bond, and suitable for the production of water-soluble polymer, and moreover allows the high-yield production of water-soluble polymer. A process of producing this composition and a water-soluble monomer-containing composition obtained therefrom are also provided. A water-soluble monomer is also provided that can be used as a starting material for a water-soluble polymer that even at high hardnesses exhibits an excellent capacity to capture metal ions such as the calcium ion and magnesium ion, an excellent anti-gelation performance, an excellent anti-soil redeposition performance, a better anti-dye transfer performance than in the past, and also an excellent compatibility with surfactants.
    Type: Application
    Filed: December 3, 2010
    Publication date: September 20, 2012
    Applicant: NIPPON SHOKUBAI CO., LTD.
    Inventors: Atsuro Yoneda, Makoto Saito, Aki Tsukajima, Daisuke Michitaka, Mitsuaki Makino
  • Patent number: 8097741
    Abstract: The invention relates to solvent-containing two-component polyurethane moisture cured hybrid sol-gel coating formulation comprising 1) an epoxy-functional binder with carbamate functionality and 2) a blended curing component comprising at least one sol gel precursor and an amine crosslinker.
    Type: Grant
    Filed: March 31, 2008
    Date of Patent: January 17, 2012
    Assignee: NDSU Research Foundation
    Inventors: Dean C. Webster, Dipak Chattopadhyay
  • Patent number: 8039537
    Abstract: A modified bismaleimide resin of Formula (I) or (II) is provided. In Formula (I) or (II), Q is —CH2—, —C(CH3)2—, —O—, —S—, —SO2— or null, R is —(CH2)2—, —(CH2)6—, —(CH2)8—, —(CH2)12—, —CH2—C(CH3)2—CH2—CH(CH3)—CH2—CH2—, 10<n<500, and x+y=n. The invention also provides a method for preparing a modified bismaleimide resin and a composition including the modified bismaleimide resin.
    Type: Grant
    Filed: February 22, 2010
    Date of Patent: October 18, 2011
    Assignee: Industrial Technology Research Institute
    Inventors: Feng-Po Tseng, Lu-Shih Liao, Kuo-Chan Chiou
  • Publication number: 20110200582
    Abstract: Disclosed are formulation and optimization protocols for delivery of therapeutically effective amounts of biologically active agents to liver, tumors, and/or other cells or tissues. Also provided are compositions and uses for cationic lipid compounds of formula (I). The invention also relates to compositions and uses for stealth lipids of formula (XI). Also provided are processes for making such compounds, compositions, and formulations, plus methods and uses of such compounds, compositions, and formulations to deliver biologically active agents to cells and/or tissues.
    Type: Application
    Filed: December 21, 2010
    Publication date: August 18, 2011
    Applicant: NOVARTIS AG
    Inventors: Jeremy BARYZA, Keith BOWMAN, Andrew GEALL, Tanzina LABONTE, Cameron LEE, Chandra VARGEESE, Laura WEST, Junping ZHAO
  • Patent number: 7868192
    Abstract: The present invention relates to a process for producing glycidol from glycerol carbonate by subjecting the glycerol carbonate to decarboxylation reaction in the presence of a solvent containing no active hydrogen. In the process, glycidol can be produced from glycerol carbonate as a raw material of the glycidol with a high selectivity.
    Type: Grant
    Filed: July 15, 2009
    Date of Patent: January 11, 2011
    Assignee: KAO Corporation
    Inventors: Yuichiro Seki, Tomoaki Sasa, Hiroki Takeuchi, Mitsuru Uno, Masanori Namba
  • Publication number: 20100056522
    Abstract: An object of the present invention is to find a novel pharmacological effect of a compound having an HDAC inhibitory effect. The compound having an HDAC inhibitory effect of the invention has an excellent effect of cell morphological change on trabecular meshwork cells and/or effect of intraocular pressure reduction, and is therefore useful as a preventive and/or therapeutic agent for a disease considered to be associated with aqueous humor circulation and/or intraocular pressure, particularly as a preventive and/or therapeutic agent for glaucoma or ocular hypertension.
    Type: Application
    Filed: March 28, 2008
    Publication date: March 4, 2010
    Applicant: Santen Pharmaceutical Co., Ltd.
    Inventors: Shinji Yoneda, Koushi Fujisawa, Katsuhiko Watanabe, Junko Fujikawa, Atsushi Shimazaki, Tomoko Kirihara, Hisashi Tajima
  • Publication number: 20100048927
    Abstract: A process for preparing (meth)acrylic esters (F) of alcohols (A) having at least one epoxy group, in which at least one alcohol (A) having at least one epoxy group is esterified with (meth)acrylic acid (S) or is transesterified with at least one (meth)acrylic ester (D) in the presence of at least one enzyme, the alcoholic leaving group being stable under the reaction conditions in the case of the transesterification.
    Type: Application
    Filed: October 23, 2007
    Publication date: February 25, 2010
    Applicant: BASF SE
    Inventors: Dietmar Haering, Uwe Meisenburg, Mathieu Chabanas, Gunter Lipowsky
  • Publication number: 20080241742
    Abstract: A surface-treating agent for forming a resist pattern, includes: a compound represented by formula (1) as defined in the specification, wherein the surface-treating agent is used in a step between a formation of a first resist pattern on a first resist film and a formation of a second resist film on the first resist pattern to form a second resist pattern, and a pattern-forming method uses the surface-treating agent.
    Type: Application
    Filed: March 24, 2008
    Publication date: October 2, 2008
    Applicant: FUJIFILM CORPORATION
    Inventors: Wataru HOSHINO, Hideaki TSUBAKI, Masahiro YOSHIDOME
  • Publication number: 20080167389
    Abstract: The present invention provides for a composition comprising a silane having the formula: (R1)(R2)(R3)Si—R4—Si(R5)(R6)(R7) wherein R1, R2, R3, R5, and R6 are each independently selected from the group consisting of 1 to 6 monovalent hydrocarbon radicals, aryl, and a hydrocarbon group of 7 to 10 carbons containing an aryl group; R4 is a hydrocarbon group of 1 to 3 carbons; R7 comprises an anionic, cationic or zwitterionic substituent. The silanes of the present invention exhibit resistance to hydrolysis over a wide pH range.
    Type: Application
    Filed: December 10, 2007
    Publication date: July 10, 2008
    Applicant: MOMENTIVE PERFORMANCE MATERIALS INC.
    Inventors: Mark D. Leatherman, George A. Policello, Wenqing Peng, Liping Zheng, Roland Wagner, Suresh K. Rajaraman, Zijun Xia
  • Publication number: 20080153991
    Abstract: Disclosed herein are methods of making a negative pattern of carbon nanotubes or a polymerized carbon nanotube composite having an interpenetrating polymer network (IPN) by modifying the surfaces of the carbon nanotubes with polymerizable functional groups such as oxirane and anhydride groups and subjecting the surface-modified carbon nanotubes either to a photolithography process or to a heatcuring process. By virtue of the present invention, desired patterns of carbon nanotubes can be easily made on the surfaces of various substrates, and polymerized carbon nanotube composites improved in hardening properties can be made without additional polymers.
    Type: Application
    Filed: May 9, 2007
    Publication date: June 26, 2008
    Applicant: SAMSUNG ELECTRONICS CO., LTD.
    Inventors: Jong Jin Park, Jung Han Shin, Sang Yoon Lee
  • Patent number: 7129271
    Abstract: Compounds, compositions, and methods that employ an eremophilane sesguiterpene are presented for controlling an arthropod pest population. The compounds have minimal adverse or toxic effects on humans, non-human animals, and the natural environment. The compounds may be isolated from natural sources, semi-synthesized from naturally occurring compounds, or completely synthesized. The compounds may be applied directly to a pest or the locus of a pest, and function as topical or ingestible toxins. Eremophilane sesguiterpenes 13-hydroxy-valencene, valencene-11,12-epoxide, valencene-13-aldehyde, and nootkatone-1,10-11,12-diepoxide are exemplary compounds.
    Type: Grant
    Filed: December 7, 2001
    Date of Patent: October 31, 2006
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventors: Gary O. Maupin, Joseph Karchesy, Nicholas A. Panella, Marc C. Dolan
  • Patent number: 6870061
    Abstract: A continuous and scalable process for producing glycidyl nitrate, or glyn, from glycerin, nitric acid, and caustic wherein the process includes the reaction of glycerin and nitric acid to form dinitroglycerin and the reaction of dinitroglycerin with caustic, such as sodium hydroxide, system for producing the inventive material is also disclosed. The vessel, a second reaction vessel, and a separation apparatus.
    Type: Grant
    Filed: January 10, 2003
    Date of Patent: March 22, 2005
    Assignee: Alliant Techsystems Inc.
    Inventors: Thomas K. Highsmith, Harold E. Johnston
  • Patent number: 6861501
    Abstract: A process is provided in which at least one multi-functional alcohol having a hydroxyl functionality of at least two serves as a polymerization initiator. The multi-functional alcohol initiator is optionally, although preferably, reacted with a catalyst to form a catalyst-initiator complex, which is then used in the polymerization of glycidyl nitrate. The resulting poly(glycidyl nitrate) has a functionality substantially equivalent in number to the hydroxyl functionality of the multi-functional alcohol initiator. The poly(glycidyl nitrate) is cross-linked with at least one aromatic polyisocyanate having at least one aromatic ring and, on average, more than two isocyanate moieties bonded directly to the aromatic ring.
    Type: Grant
    Filed: January 22, 2002
    Date of Patent: March 1, 2005
    Assignee: Alliant Techsystems Inc.
    Inventors: Andrew J. Sanderson, Laura J. Martins, Michael A. Dewey
  • Patent number: 6809130
    Abstract: A halogen-free, phosphorus-free poly-cyclic compound is used a flame retardant. This compound has amide and hydroxy groups, and thus it is able to react with an epoxy resin to form a reactive type flame-retardant advanced epoxy resin. The advanced epoxy resin together with an inorganic additive are mixed with an epoxy resin to form a halogen-free, phosphorus-free flame-retardant epoxy composition, which can be used in the manufacture of a printed circuit board and as an encapsulation material for a semi-conductor device.
    Type: Grant
    Filed: March 11, 2003
    Date of Patent: October 26, 2004
    Assignee: Industrial Technology Research Institute
    Inventors: Kuo-Chan Chiou, Tzong-Ming Lee, Feng-Po Tseng, Lu-Shih Liao, Jia-Chi Huang, Tzu-Ting Lin
  • Patent number: 6784228
    Abstract: The present invention relates to an epoxy resin composition a cure article thereof, a novel epoxy resin used therein, a polyhydric phenol compound suited for used as an intermediate thereof, and a process for preparing the same. One of the objects to be achieved by the present invention is to exert the heat resistance, the moisture resistance, the dielectric performances and the flame-resistant effect required of electric or electronic materials such as semiconductor encapsulating materials and varnishes for circuit boards in the epoxy resin composition.
    Type: Grant
    Filed: July 9, 2002
    Date of Patent: August 31, 2004
    Assignee: Dainippon Ink and Chemicals, Inc.
    Inventors: Ichiro Ogura, Yoshiyuki Takahashi, Tomoyuki Imada
  • Patent number: 6765102
    Abstract: Water-soluble or water-dispersible branched or unbranched cationic epoxy compounds comprise a backbone having covalently attached thereto two or more epoxy moieties and one or more of the same or different organoonium moieties. The backbone comprises at least 25 weight % oxygen.
    Type: Grant
    Filed: July 29, 2002
    Date of Patent: July 20, 2004
    Assignee: Eastman Kodak Company
    Inventors: Jeffrey W. Leon, Paul R. West, Robert E. Mccovick
  • Publication number: 20040127478
    Abstract: The invention provides compounds that inhibit MMPs; methods for treating or preventing cancer, angiogenesis, arthritis, connective tissue disease, cardiovascular disease, inflammation or autoimmune disease in a mammal; a method for inhibiting a matrix metalloproteinase in vivo or in vitro; and a method for imaging a tumor in vivo or in vitro.
    Type: Application
    Filed: December 24, 2003
    Publication date: July 1, 2004
    Applicant: Wayne State University
    Inventors: Shahriar Mobashery, Rafael Fridman
  • Patent number: 6703415
    Abstract: The invention provides compounds that inhibit MMPs; methods for treating or preventing cancer, angiogenesis, arthritis, connective tissue disease, cardiovascular disease, inflammation or autoimmune disease in a mammal; a method for inhibiting a matrix metalloproteinase in vivo or in vitro; and a method for imaging a tumor in vivo or in vitro.
    Type: Grant
    Filed: May 3, 2001
    Date of Patent: March 9, 2004
    Assignee: Wayne State University
    Inventors: Shahriar Mobashery, Rafael Fridman
  • Patent number: 6677468
    Abstract: In accordance with the present invention, methods have been developed for the reduction of the chloride content of epoxy compound starting materials. Invention methods comprise fractionating an epoxy compound starting material into portions (e.g., fractions or cuts) having different chloride content relative to the epoxy compound starting material. Certain of these collected portions (i.e., the portions fractionated and collected after collection of the forecut and before discontinuation of the fractionation) contain substantially reduced chloride levels relative to the epoxy compound starting material.
    Type: Grant
    Filed: July 24, 2001
    Date of Patent: January 13, 2004
    Assignee: Loctite Corporation
    Inventors: Mark T. Dimke, Richard E. Miller
  • Patent number: 6627683
    Abstract: Curable compositions, reaction products of which are reworkable through thermal decomposition, are provided. Specific compounds useful in such curable compositions, as well as curable compositions and thermosets incorporating such compounds, are provided in the present invention. The compounds include a cyclic hydrocarbon moiety including an oxirane or thiirane group and an aromatic ether moiety including an oxirane or thiirane group. The cyclic hydrocarbon moiety and the aromatic ether moiety are joined to each other through an oxycarbonyl-containing linkage or a thiocarbonyl-containing linkage, preferably a secondary or tertiary linkage. Compositions incorporating such compounds are capable of curing by exposure to a specific temperature, and are decomposable at a temperature in excess of the curing temperature, thus providing a composition which is reworkable.
    Type: Grant
    Filed: September 5, 2000
    Date of Patent: September 30, 2003
    Assignee: Henkel Loctite Corporation
    Inventors: Philip T. Klemarczyk, Lie-Zhong Gong
  • Patent number: 6613849
    Abstract: The terminal glydidyl groups of a diglycidyl ether of a hydroxyaliphatic bisphenol is optionally reacted with (meth)acrylic acid to obtain a vinyl ester. The internal hydroxyaliphatic groups are reacted with (meth)acrylic acid or cyanoacrylic acid to prepare a diglycidyl and/or (meth)acrylate-terminated (meth)acrylate or urethane acrylate.
    Type: Grant
    Filed: November 16, 2001
    Date of Patent: September 2, 2003
    Assignee: The Dow Chemical Company
    Inventors: Louis L. Walker, Robert E. Hefner, Jr., Katherine S. Clement
  • Patent number: 6590018
    Abstract: Compounds containing vinyl silane and epoxy functionality can be used as adhesion promoters or the main resin in curable compositions.
    Type: Grant
    Filed: September 28, 2001
    Date of Patent: July 8, 2003
    Assignee: National Starch and Chemical Investment Holding Corporation
    Inventor: Osama M. Musa
  • Patent number: 6586607
    Abstract: A process for the preparation of diglycidylether of alkoxylated resorcinol using novel catalysts is disclosed. In particular, it has been found that antimony, indium and tellurium halides are effective catalysts for preparation of the diglycidylether of alkoxylated resorcinol.
    Type: Grant
    Filed: April 11, 2002
    Date of Patent: July 1, 2003
    Assignee: Indspec Chemical Corporation
    Inventors: Raj B. Durairaj, Gary A. Jesionowski
  • Patent number: 6572980
    Abstract: This invention relates to thermosetting resin compositions useful for mounting onto a circuit board semiconductor devices, such as CSPs, BGAs, LGAs and the like, each of which having a semiconductor chip, such as LSI, on a carrier substrate. The compositions of this invention are reworkable when subjected to appropriate conditions.
    Type: Grant
    Filed: April 2, 2002
    Date of Patent: June 3, 2003
    Assignee: Henkel Loctite Corporation
    Inventors: Philip T. Klemarczyk, Andrew D. Messana
  • Patent number: 6566541
    Abstract: Novel compounds that are anti-angiogenic or immunosuppressive are described. Also described are methods for determining if an animal is at risk for a disease involving abnormal angiogenesis or an immune reaction resulting in pathology comprising evaluating an aspect of MetAP2 metabolism or structure; methods for identifying agents that are anti-angiogenic or immunosuppressive comprising evaluating the effect of the agent on an aspect of MetAP2 metabolism; methods for treating a cell having an abnormality in metabolism or structure of MetAP2; and methods for treating abnormal angiogenesis or an immune reaction which results in pathology in an animal. Pharmaceutical compositions are also provided.
    Type: Grant
    Filed: March 21, 2001
    Date of Patent: May 20, 2003
    Assignee: Massachusetts Institute of Technology
    Inventors: Jun O. Liu, Eric C. Griffith, Zhuang Su
  • Patent number: 6559268
    Abstract: A perfluoro group-containing compound are represented by the following formula (I): —Rf— is a perfluoro group; and —A represents —OH or a group: or —CyF2y+1 or —CzF2z−1 and a perfluoro group-containing polymerizable compound represented by the following formula (II): R1—O—CH2—CH(OH)—CH2—O—Rf—B  (II) In Formula (II), —Rf— is a perfluoro group; —B is —OH or —O—CH2—CH(OH)—CH2—O—R2, or —CyF2y+1 or —CzF2z−1; and R1 and R2 each is a dehydroxyl residue of a (meth)acryloyl group-containing compound or a vinyl group-containing compound. The hardened polymer from the compound has water-repellency, oil-repellency and adhering ability.
    Type: Grant
    Filed: March 17, 2000
    Date of Patent: May 6, 2003
    Assignee: Kyoeisha Chemcial Co., Ltd.
    Inventors: Junichi Ikeda, Hajimu Kawa
  • Patent number: 6538142
    Abstract: A process for the preparation of 5-(3,5-dimethylphenoxymethyl)-2-oxazolidinone, which includes: a) reacting 3,5-dimethylphonel with epichlorohydrin to obtain a mixture of 1-(3,5-dimethylphenoxy)2,3-epoxy propane (1) and 1-(3,5-dimethylphenoxy)-3-chloro-2-propanol (2); b) reacting the mixture of (1) and (2) obtained from step (a) with benzylamine to obtain a first compound; c) reducing the first compound with hydrogen in presence of ammonia, to obtain a second compound; and d) reacting the second compound with dimethylcarbonate in the presence of a strong base to obtain 5-(3,5-dimethlphenoxymethyl)-2-oxazolidinone.
    Type: Grant
    Filed: April 18, 2002
    Date of Patent: March 25, 2003
    Assignee: Farchemia S.r.l.
    Inventors: Gabriele Breviglieri, Sergio Contrini, Giacomo Bruno, Cinzia Assanelli
  • Patent number: 6353079
    Abstract: The present invention concerns hydroxyaliphatic functional diglycidyl ethers of bisphenols (epoxy resins); curable (thermosettable) mixtures of at least one hydroxyaliphatic functional epoxy resin and at least one curing agent and/or catalyst therefor, as well as cured (thermoset) compositions prepared therefrom; and derivatives prepared therefrom. The bisphenol precursor to the diglycidyl ether contains a hydroxyaliphatic group linkage between the two aromatic rings of the bisphenol.
    Type: Grant
    Filed: July 26, 2000
    Date of Patent: March 5, 2002
    Assignee: The Dow Chemical Company
    Inventors: Louis L. Walker, Robert E. Hefner, Jr., Katherine S. Clement
  • Patent number: 6248854
    Abstract: An epoxysiloxane condensate is modified by means of an in situ reaction with an organic compound, which is di-functional or multifunctional if warranted. By means of the disclosed method, the characteristics of epoxysiloxane condensates, epoxy resin mixtures, epoxy resin formulations and molded bodies manufactured therefrom can be varied easily and economically.
    Type: Grant
    Filed: January 26, 1999
    Date of Patent: June 19, 2001
    Assignee: Siemens Aktiengesellschaft
    Inventors: Klaus Höhn, Ernst Wipfelder
  • Patent number: 6242618
    Abstract: Invention relates to H2S scavengers polysulfide compounds and methods for scavenging H2S from polysulfide compounds. Furthermore, the invention uses a scavenger for selectively reducing the levels of hydrogen sulfide present in a polysulfide product.
    Type: Grant
    Filed: March 21, 2000
    Date of Patent: June 5, 2001
    Assignee: The Lubrizol Corporation
    Inventors: David R. Forester, Bharat B. Malik
  • Patent number: 6239204
    Abstract: A crosslinked material of a polyether copolymer comprising: (A) 1 to 98% by mol of a repeating unit derived from a monomer represented by the formula (I): (B) 95 to 1% by mol of a repeating unit derived from a monomer represented by the formula (II): (C) 0.005 to 15% by mol of a repeating unit derived from a monomer having one epoxy group and at least one reactive functional group; provides a polymer solid electrolyte which is superior in ionic conductivity and also superior in processability, moldability, mechanical strength and flexibility, furthermore thermal resistance.
    Type: Grant
    Filed: October 21, 1998
    Date of Patent: May 29, 2001
    Assignee: Baiso Co., Ltd.
    Inventors: Katsuhito Miura, Shigeru Shoji, Takahiro Sakashita, Yasuo Matoba
  • Patent number: 6211389
    Abstract: In accordance with the present invention, methods have been developed for the reduction of the chloride content of epoxy compound starting materials. Invention methods comprise subjecting specifically defined combinations comprising an epoxy resin starting material and other components to conditions sufficient to produce a treated epoxy compound (i.e., an epoxy compound having a chloride content which is reduced relative to that of the epoxy resin starting material), and separating the treated epoxy compound from the combination. Other components contemplated for use in the practice of the present invention comprise, alternatively, mixtures of crown ether, organic solvent and suitable base; mixtures of crown ether-like solvent and suitable base; mixtures of aprotic solvents and hydrides (other than tin hydride); mixtures of nonhalogenated organic solvent and reducing metal; and the like. In accordance with a further aspect of the present invention, products (i.e.
    Type: Grant
    Filed: May 23, 2000
    Date of Patent: April 3, 2001
    Assignee: Dexter Corporation
    Inventor: Mark Thomas Dimke
  • Patent number: 6207704
    Abstract: Novel compounds that are anti-angiogenic or immunosuppressive are described. Also described are methods for determining if an animal is at risk for a disease involving abnormal angiogenesis or an immune reaction resulting in pathology comprising evaluating an aspect of MetAP2 metabolism or structure; methods for identifying agents that are anti-angiogenic or immunosuppressive comprising evaluating the effect of the agent on an aspect of MetAP2 metabolism; methods for treating a cell having an abnormality in metabolism or structure of MetAP2; and methods for treating abnormal angiogenesis or an immune reaction which results in pathology in an animal. Pharmaceutical compositions are also provided.
    Type: Grant
    Filed: June 8, 1998
    Date of Patent: March 27, 2001
    Assignee: Massachusetts Institute of Technology
    Inventors: Jun O. Liu, Eric C. Griffith, Zhuang Su
  • Patent number: 6177577
    Abstract: This invention relates to novel dicationic and polycationic monoprimary alcohol compounds and their derivatives, represented by the formula wherein each alk is independently alkyl of 1-8 carbon atoms; each ALK is independently alkyl of 1-8 carbon atoms; each R1, R2, R3, R4 or R5 is independently H or alkyl of 1-8 carbon atoms; n is 2-5; G is H, CR1R2CR3OHCR4R5X or X is Cl, Br or I; An− is an anion and p is 1-10; provided that the compound is soluble in water.
    Type: Grant
    Filed: November 15, 1991
    Date of Patent: January 23, 2001
    Assignee: The Dow Chemical Company
    Inventors: Dorothy L. Roerden, R. Keith Frank
  • Patent number: 6153589
    Abstract: The present invention is related to compounds, compositions and methods of treating viral infections. Compounds of the present invention have the following general formula: ##STR1## wherein R is selected from --CH.sub.2 OH, --CO.sub.2 R.sup.2, --CONR.sup.3 R.sup.4, or COR.sup.5, wherein R.sup.2 is hydrogen or a lower alkyl group, R.sup.3 and R.sup.4 are each independently hydrogen or a lower alkyl group, R.sup.5 is an amino acid residue bound via a terminal nitrogen or peptide having at least two amino acid residues; and wherein R.sup.1 is C.sub.5 -C.sub.13 alkyl, aryl, aralkyl, aralkyl(lower alkyl)ether, or C.sub.5 -C.sub.13 alkyl(lower alkyl)ether.
    Type: Grant
    Filed: December 15, 1992
    Date of Patent: November 28, 2000
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventors: Jeffrey J. Blumenstein, Christopher J. Michejda, Stephen Oroszlan, Terry Copeland
  • Patent number: 6127558
    Abstract: Epoxy resins which are diglycidyl ethers of tetrabromobisphenol A having a crystalline structure and in particulate form have an epoxy equivalent weight between 320 and 380 g/eq and a chlorine content that is smaller than 0.3%.
    Type: Grant
    Filed: May 5, 1998
    Date of Patent: October 3, 2000
    Assignee: Bromine Compounds Ltd.
    Inventors: Yoav Bar-Yaakov, Daniel Plewinski
  • Patent number: 6048956
    Abstract: The present invention relates to a diglycidyl ether represented by the following general formula (I): ##STR1## (wherein, R.sup.1 and R.sup.2 are the same or different, and represent lower alkyl having 1.about.6 carbon atoms), a composition including the glycidyl ether and epoxy resin, and epoxy resin cured product obtained by the composition. The glycidyl ether can be used as a reactive diluent for epoxy resins.
    Type: Grant
    Filed: November 3, 1998
    Date of Patent: April 11, 2000
    Assignee: Kyowa Yuka Co., Ltd.
    Inventors: Kenji Muto, Toshikazu Murayama, Nobuko Tsuzaki
  • Patent number: 6048991
    Abstract: Alpha-hydroxy-epoxides of alpha-alkoxy-epoxides of the formula IV ##STR1## in which the substituents have the following meanings: R.sup.7, R.sup.8, R.sup.9, R.sup.10, R.sup.11 are independently hydrogen, C.sub.1 -C.sub.20 -alkyl, C.sub.3 -C.sub.12 -cycloalkyl, C.sub.4 -C.sub.20 -cycloalkylalkyl, C.sub.1 -C.sub.20 -hydroxy-alkyl, a heterocyclic ring, or an aryl or C.sub.7 -C.sub.20 -arylalkyl group optionally substituted by C.sub.1 -C.sub.8 -alkyl, C.sub.1 -C.sub.8 -alkoxy, halogen, C.sub.1 -C.sub.4 -haloalkyl, C.sub.1 -C.sub.4 -halo-alkoxy, phenyl, phenoxy, halophenyl, halophenoxy, carboxy, C.sub.2 -C.sub.8 -alkoxycarbonyl, or cyano, or R.sup.7 and R.sup.8 or R.sup.7 and R.sup.9 or R.sup.7 and R.sup.10 or R.sup.9 and R.sup.10 or R.sup.10 and R.sup.11 together form a (CH.sub.2).sub.n group in which n is an integer from 1 to 10 and which may be optionally substituted by C.sub.1 -C.sub.8 -alkyl, C.sub.1 -C.sub.8 -alkoxy, and/or halogen, andR.sup.12 is hydrogen, C.sub.1 -C.sub.8 -alkyl, or benzyl,provided that R.
    Type: Grant
    Filed: January 21, 1999
    Date of Patent: April 11, 2000
    Assignee: BASF Aktiengesellschaft
    Inventor: Dieter Haermeling
  • Patent number: 5998518
    Abstract: A description is given of compounds of the formula I ##STR1## where R.sup.1 is H, C.sub.1 -C.sub.12 alkyl, C.sub.2 -C.sub.12 alkenyl, C.sub.2 -C.sub.12 alkynyl, O--C.sub.1 -C.sub.12 alkyl, CO--C.sub.1 -C.sub.12 alkyl, in which radicals alkyl chains may also be interrupted by O, S, S.dbd.O, SO.sub.2 or N--C.sub.1 -C.sub.12 alkyl, or is C.sub.5 -C.sub.12 cycloalkyl which is unsubstituted or substituted by1 to 4 C.sub.1 -C.sub.4 alkyl and/or C.sub.1 -C.sub.4 alkoxy radicals, O--C.sub.5 -C.sub.12 cycloalkyl, which is unsubstituted or substituted by 1 to 4 C.sub.1 -C.sub.4 alkyl and/or C.sub.1 -C.sub.4 alkoxy radicals, CO--C.sub.6 -C.sub.14 aryl, which is unsubstituted or substituted by 1 to 9 C.sub.1 -C.sub.4 alkyl and/orC.sub.1 -C.sub.4 alkoxy radicals, O-benzyl, which on the aromatic ring is unsubstituted or substituted by 1 to 4 C.sub.1 -C.sub.4 alkyl and/or C.sub.1 -C.sub.4 alkoxy radicals, CO-benzyl, which on the aromatic ring is unsubstituted or substituted by 1 to 4 C.sub.1 -C.sub.4 alkyl and/or C.sub.
    Type: Grant
    Filed: October 15, 1997
    Date of Patent: December 7, 1999
    Assignee: Ciba Specialty Chemcials Corporation
    Inventor: Alfred Steinmann
  • Patent number: 5965753
    Abstract: A process for preparation of a glycidyl sulfonate derivative with high purity and in high yield, which is characterized in reacting glycidol which is prepared from treating 3-chloro-1,2-propanediol in an aqueous solvent in the basic condition, without isolating the resulting glycidol with a sulfonyl halide in a two phase solvent consisting of an organic solvent and water in the presence of an inorganic base and a tertiary amine or a pyridine derivative.
    Type: Grant
    Filed: July 20, 1998
    Date of Patent: October 12, 1999
    Assignee: Daiso Co., LTd.
    Inventors: Midori Masaki, Yoshiro Furukawa, Keishi Takenaka
  • Patent number: 5866036
    Abstract: Chiral nonracemic molecules which are useful as high tilt, high polarization and/or high birefringence FLC materials or are useful as components of such FLC materials and which have the following general structure are provided:RO--(Ph.sub.1).sub.m --(A).sub.a --(Ph.sub.2).sub.n --(B).sub.b --(Ph.sub.3).sub.p --Twhere Ph.sub.1, Ph.sub.2 and Ph.sub.
    Type: Grant
    Filed: February 2, 1994
    Date of Patent: February 2, 1999
    Assignee: Displaytech, Inc.
    Inventors: Michael D. Wand, Rohini T. Vohra, David M. Walba, Sean D. Monahan
  • Patent number: 5783712
    Abstract: The invention relates to compounds having at least one vinyl ether group which also contain in the molecule at least one further functional group selected from acrylate, methacrylate, epoxy, alkenyl, cycloalkenyl and vinylaryl groups, to compositions, especially for stereolithography, comprising those vinyl ether compounds, and to a method of producing three-dimensional objects using those compositions.
    Type: Grant
    Filed: August 13, 1996
    Date of Patent: July 21, 1998
    Assignee: Ciba Specialty Chemicals Corporation
    Inventors: Bettina Steinmann, Adrian Schulthess, Max Hunziker
  • Patent number: 5627292
    Abstract: The invention relates to monomers derived from perhalogenated sultones, to a process for their preparation, to the polymers obtained from the said monomers and to their use for the production of ion-conductive materials.The monomers are compounds corresponding to the formula A--CFX--SO.sub.2 Z in which A denotes one groups [sic] R.sup.3 --O--CF.sub.2 -- or R.sup.3 -- or R.sup.1 R.sup.2 N--CO--; Z denotes F, Cl, --OSi(CH.sub.3).sub.3 or an ionic group, Z being other than F when A denotes R.sup.3 --O--CF.sub.2 -- or R.sup.3 --; X denotes F, Cl, H or R.sub.F, X being R.sub.F when A denotes R.sup.3 --; the radicals R.sup.1, R.sup.2 and R.sup.3 are chosen from polymerizable nonperfluorinated organic radicals; R.sub.F is chosen from perfluoroalkyl radicals and perfluoroaryl radicals.The polymers obtained from these monomers can be employed for the production of ion-conductive materials.
    Type: Grant
    Filed: March 9, 1994
    Date of Patent: May 6, 1997
    Assignees: Centre National de la Recherche Scientifique, Hydro-Quebec
    Inventors: Michel Armand, Jean-Yves Sanchez, Salime Sylla
  • Patent number: 5532225
    Abstract: Acyclic purine phosphonate nucleotide analogs useful to treat herpes viral infections are provided in enantiomerically pure form. These antiviral agents have the structural formula (Ia) or (Ib) ##STR1## and may be in acid, salt or ester form. Such compounds may also be dehydrated to provide antiviral agents in cyclic form. Pharmaceutical compositions are provided containing the antiviral agents, as is a chiral synthesis which may be used to prepare the agents in enantiomerically pure form or as a racemic mixture.
    Type: Grant
    Filed: July 31, 1992
    Date of Patent: July 2, 1996
    Assignee: SRI International
    Inventors: Elmer J. Reist, Beatrice Ruhland-Fritsch, Pricilla A. Sturm
  • Patent number: 5514818
    Abstract: A method of resolving a mixture of stereoisomers of an aliphatic epoxide containing two or less oxygen atoms is provided. The method comprises utilizing a polysaccharide or a derivative thereof as a resolving agent.
    Type: Grant
    Filed: February 10, 1995
    Date of Patent: May 7, 1996
    Assignee: Daicel Chemical Industries, Ltd.
    Inventor: Kozo Tachibana