Abstract: A thermoelectric assembly for powering one or more electromagnetic valves of a cooking appliance. According to one embodiment the assembly includes a main current circuit that includes a thermocouple, a cable configured for electrically connecting the thermocouple with an electromagnetic valve, and a transistor connected to the cable and configured for de-energizing the electromagnetic valve. The main current circuit also includes a connection module that includes a power supply connected to the transistor, the power supply having input terminals configured for being connected to an external energy source, a rectifier, and a resistive block connected between one of the input terminals and the rectifier, the resistive block being configured for minimizing the current circulating through the power supply to a value equivalent to the galvanic isolation.

Abstract: The disclosure provides compounds and methods of using Apogossypolone derivatives for treating diseases and disorders. In particular, the disclosure provides compounds of Formula I: or a pharmaceutically acceptable salt, hydrate, or solvate thereof, and provides methods for the preparation of compounds of Formula I; and methods for treating cancer, autoimmune diseases, and inflammation by administering a compound of Formula I.

Abstract: Novel crystalline forms of anti Pneumocystis carinii compound (2-[4-(4-Chlorophenyl)cyclohexyl]-3-hydroxy-1,4-naphthoquinone) commonly known as Atovaquone and methods for producing the same is disclosed herein. This also provides pharmaceutical compositions comprising the said polymorphs of Atovaquone and method of treating Pneumocystis carinii pneumonia, the method comprising administering to a warm blooded animal an effective amount of a product-by-process composition of matter comprising polymorphic forms of Atovaquone.

Abstract: A method for producing menatetrenone that does not have a deleterious influence on the environment, that is safe even when applied to large-scale production, and that is also simple to operate, wherein a compound represented by the following formula (1) is produced by treating with an oxygen source, and without the addition of an additive other than water or aqueous sodium chloride solution, a reaction solution consisting essentially of a solution of a compound represented by the following formula (2) dissolved in a solvent:

Abstract: Methods for treating, preventing, or inhibiting diseases and disorders associated with inflammation, cell-proliferation, and pain comprising the administration of a compound having the structural formula wherein R1 is a hydrogen, alkyl, aryl, hydroxyalkyl, cycloalkyl, cycloalkenyl, carboxylic acid, alkylamino or amide group having from 2 to 20 carbon atoms, R2, R3, and R4 are each independently hydrogen or an acyl residue having from 1 to 6 carbon atoms, R5 is hydrogen, CH3, or CH2OH, and R6 is an organo group such as a hydrocarbon having from 1 to 10 carbon atoms are disclosed. Other seco-pseudopterosins and compounds related to pseudopterosins are disclosed.

Abstract: Disclosed are processes for separating valuable products, including unsaponifiable materials, from any given matrix of raw materials that is mainly composed of saponifiable components and unsaponifiable components. Preferred methods include converting sodium or potassium soaps obtained from the saponification of a starting material into metallic soaps which have a lower melting point, and when melted, have viscosity sufficiently low to enable processing such as by distillation evaporation processes. Preferred raw materials include animal or vegetable products, as well as by-products, residues, and waste products from the processing of animal or vegetable products, such as from food processing, cellulose processing and the like. Valuable products which may be obtained by the disclosed processes include sterols, vitamins, flavonoids, and tocopherols.

Abstract: This invention provides analogs of triptycene which are useful as anticancer drugs, as well as for other uses. The potency of these compounds is in a similar magnitude as daunomycin, a currently used anticancer drug. Each compound of the invention produces one or more desired effects (blocking nucleoside transport, inhibiting nucleic acid or protein syntheses, decreasing the proliferation and viability of cancer cells, inducing DNA fragmentation or retaining their effectiveness against multidrug-resistant tumor cells).

Abstract: A method is described for the simultaneous preparation of p-bromophenols and p-benzoquinones, intermediates useful in the preparation of hydroquinones and 4,4′-dihydroxybiphenyls, respectively. Hydroquinones and 4,4′-dihydroxybiphenyls are useful monomers for the preparation of a variety of polymers. The method also comprises reducing the p-benzoquinone to its corresponding hydroquinone in the presence of the p-bromophenol. Limiting the amount of HBr present in the reaction mixture was shown to control the amount of benzoquinone produced. The method also allows for the recycling of many of the reagents used, thereby reducing the cost of producing each monomer.

Abstract: Methods for treating, preventing, or inhibiting diseases and disorders associated with inflammation, cell-proliferation, and pain comprising the administration of a compound having the structural formula wherein R1 is a hydrogen, alkyl, aryl, hydroxyalkyl, cycloalkyl, cycloalkenyl, carboxylic acid, alkylamino or amide group having from 2 to 20 carbon atoms, R2, R3, and R4 are each independently hydrogen or an acyl residue having from 1 to 6 carbon atoms, R5 is hydrogen, CH3, or CH2OH, and R6 is an organo group such as a hydrocarbon having from 1 to 10 carbon atoms are disclosed. Other seco-pseudopterosins and compounds related to pseudopterosins are disclosed.

Abstract: The invention relates to polycyclic aryl and heteroaryl substituted 1,4-quinone compounds useful as inhibitors of serine proteases of the coagulation cascade and compounds, compositions and methods for anticoagulant therapy for the treatment and prevention of a variety of thrombotic conditions including coronary artery and cerebrovascular diseases.

Abstract: A novel NF-&kgr;B inhibitor represented by the following formula (I) is provided.

Abstract: The present invention relates to prodrug compounds, compositions and methods useful for preventing and treating thrombotic conditions in mammals. The prodrug compounds of the present invention selectively inhibit certain proteases of the coagulation cascade.

Abstract: A substituted benzoic acid derivative which is represented by the following formula (I) and has an NF-&kgr;B inhibiting action (in the formula, R3, R4 and R5 each independently represents a hydrogen atom, an alkyl group having 1 to 6 carbon(s) or an alkoxy group having 1 to 6 carbon(s); R9 and R10 each independently represents a hydrogen atom, an alkyl group having 1 to 6 carbon(s) or an acyl group having 2 to 11 carbons); R2 represents an optionally-substituted aromatic hydrocarbon group or an optionally-substituted heterocyclic group; and X represents a carboxyl group which may be esterified or amidated).

Abstract: New enone derivatives and conjugates are described. These compounds can be used as cancer therapeutics.

Abstract: Disclosed are processes for separating valuable products, including unsaponifiable materials, from any given matrix of raw materials that is mainly composed of saponifiable components and unsaponifiable components. Preferred methods include converting sodium or potassium soaps obtained from the saponification of a starting material into metallic soaps which have a lower melting point, and when melted, have viscosity sufficiently low to enable processing such as by distillation/evaporation processes. Preferred raw materials include animal or vegetable products, as well as by-products, residues, and waste products from the processing of animal or vegetable products, such as from food processing, cellulose processing and the like. Valuable products which may be obtained by the disclosed processes include sterols, vitamins, flavonoids, and tocopherols.

Abstract: A method of oxidizing trimethylphenol (TMP) to trimethylbenzoquinone (TMBQ) by various molecular sieves containing various transition metals. In this method, TMP, a molecular sieve containing a transition metal in its framework, an oxidant and a solvent are mixed together to form a reaction system. The reaction system reacting at a temperature of about room temperature to 150° C. to obtain TMBQ, and the concentration of TMP is about 5-60% wt.

Abstract: The present invention describes a process for the preparation of 2-Methyl-1,4-naphthoquinone by oxidising 2-metbylnaphthalene with hydrogen peroxide in the presence of acetic acid.

Abstract: The invention relates to the use of compounds of the formula R1aRebOc.Ld  (I), in which and the total of a, b and c is such as to comply with the pentavalency or heptavalency of rhenium, with the proviso that c is not larger than 3×b, and in which R1 is absent or identical or different, and is an aliphatic hydrocarbon radical having 1 to 10 carbon atoms, an aromatic hydrocarbon radical having 6 to 10 carbon atoms or an arylalkyl radical having 7 to 9 carbon atoms, it being possible for the R1 radicals where appropriate to be substituted identically or differently, independently of one another, as catalysts for oxidizing electron-rich aromatic compounds and their derivatives, the catalysts being employed in a peroxide-containing solution in the presence of an anhydride of a carboxylic acid and/or of a dehydrating agent.

Abstract: Compounds for use in the treatment of heart disease include a superoxide scavenger and an organic nitrate or nitrite moiety. The compounds can be represented by the formula (A)n(B)m, in which A is a superoxide scavenger, B is an organic nitrate or organic nitrite moiety, and n and m are values between 1 and 8. These compounds do not suffer from the problem of patient tolerance that is associated with the use of conventional agents such as organic nitrates.

Abstract: The invention relates to polycyclic aryl and heteroaryl substituted 1,4-quinone compounds useful as inhibitors of serine proteases of the coagulation cascade and compounds, compositions and methods for anticoagulant therapy for the treatment and prevention of a variety of thrombotic conditions including coronary artery and cerebrovascular diseases.

Abstract: A working solution for producing hydrogen peroxide, containing an alkylanthraguinone working compound dissolved in a solvent, is regenerated by contacting the working solution with a catalyst containing from 5% to 100% boehmite at a temperature of 25° C. to 150° C. At least a portion of the tetrahydro-alkylanthraquinone epoxide present in the working solution is converted to working compound to maintain the composition of the working solution within specified limits.

Abstract: This invention relates to certain naphthoquinone derivatives of the general formula ##STR1## or a salt thereof, in which m, n, R, R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, R.sup.6, R.sup.7, R.sup.8 are as defined in the description; processes for their preparation; compositions containing such compounds and their use as a pesticide, such as a fungicide and, especially, an insecticide or an acaricide.

Abstract: Compounds of formula (A), wherein R.sub.1, R.sub.2, R.sub.3, Y and Z are organic substituents, are useful in the diagnosis of amyloidosis; some of the compounds of formula (A) are novel. Processes for their preparation, and pharmaceutical compositions containing them are also described.

Abstract: The present invention provides a naphthoquinone derivative represented by the general formula (1): ##STR1## wherein R.sup.1 represents an aryl group which may have a substituent; and R.sup.2 represents an alkylene group which may have a substituent, an arylene group which may have a substituent, etc.

Abstract: The invention relates to the use of compounds of the formulaRe.sub.a O.sub.b X.sub.c L.sub.d, (I)in whichX=F, Cl, Br, I or OH,L=Lewis base,a=an integer 1, 2 or 3b=zero or an integer from 2 to 9,c=zero or an integer from 1 to 9,d=zero or an integer from 1 to 6,and the sum of a, b and c is such that it is appropriate to the zerovalency or trivalency to heptovalency of the rhenium with the proviso that if b is not equal to zero, b.gtoreq.2.multidot.a, as catalysts for the oxidation of electron-rich aromatic compounds and derivatives thereof and a process for the oxidation of electron-rich aromatic compounds, in which electron-rich C.sub.6 -C.sub.22 aryl compounds and derivatives thereof are oxidized in an organic solvent in the presence of a catalyst of the formula (I) and of a peroxide-containing compound.

Abstract: An oil-soluble lubricating oil and fuel additive, useful as a multifunctional viscosity modifier comprising succinimide and other amine-containing polymers reacted with a quinone or substituted quinone adducts. Suitable polymers are those containing primary or secondary amine groups such as EPSA-PAM and EPDM-amine polymers. The multifunctional viscosity modifier additive provides improved dispersancy and antioxidancy to a lubricating oil or fuel composition.

Abstract: The invention relates to the use of compounds of the formula IR.sup.1.sub.a Re.sub.b O.sub.c (I),where a is from 1 to 6, b is from 1 to 4 and c is from 1 to 14 and the sum of a, b and c is in accordance with the valence of from 5 to 7 of the rhenium, with the proviso that c is not greater than 3.multidot.b, and where R.sup.1 is identical or different and is an aliphatic hydrocarbon radical having from 1 to 10 carbon atoms, an aromatic hydrocarbon radical having from 6 to 10 carbon atoms or an arylalkyl radical having from 7 to 9 carbon atoms, with the radicals R.sup.1 being able, if desired, to be identically or differently substituted independently of one another and, in the case of .sigma.-bonded radicals, at least one hydrogen atom still being bonded to the carbon atom in the .alpha. position, as catalysts for the oxidation of electron-rich aromatic compounds and their derivatives and to a process for the oxidation of electron-rich aromatic compounds which comprises oxidizing electron-rich C.sub.6 -C.sub.

Abstract: The present invention relates to intermediates useful for the preparation of vitamin K derivatives.

Abstract: Quinone derivatives of the general formula: ##STR1## (wherein R.sup.1 and R.sup.2 are the same or different, and independently are a hydrogen atom or a methyl or methoxy group, or R.sup.1 and R.sup.2 combine with each other to represent --CH.dbd.CH--CH.dbd.CH--; R.sup.3 is a hydrogen atom or a methyl group; R.sup.4 is an aliphatic, aromatic or heterocyclic group which may be substituted; R.sup.5 is a methyl or methoxy group, a hydroxymethyl group which may be substituted or a carboxyl group which may be esterified or amidated; Z is a group represented by --C.tbd.C--, --CH.dbd.CH--, ##STR2## n is an integer of 0 to 10; m is an integer of 0 to 3; k is an integer of 0 to 5, provided, however, that in the case of m being 2 or 3, Z and k can vary arbitrarily within the bracketed repeating units) are novel compounds, possess metabolism ameliorating action for polyunsaturate fatty acids, particularly production inhibitory activity of lipid peroxides (antioxidant activity), thromboxane A.sub.

Abstract: Anthraquinone compounds of the formula: ##STR1## wherein: R.sup.1 is hydrogen, hydroxy or acyloxy,R.sup.2 is hydrogen or acyl,R.sup.3 is acyl,R.sup.4 is hydrogen or acyl,R.sup.5 is hydrogen or acyl,R.sup.6 is hydrogen or acyl, andR.sup.7 is hydrogen or acylhave been found to possess endothelin antagonistic properties and are producible by various synthetic and fermentation processes.

Abstract: Phenols are oxidated to quinones with hydrogen peroxide in the presence of catalytic amounts of bromine, iodine, hydrogen bromide and hydrogen iodide.

Abstract: Naphthoquinone having a purity of higher than 95% is separated from an aqueous slurry of naphthoquinone and phthalic acid prepared by contacting, with an aqueous medium, a reaction mixture gas containing naphthoquinone and phthalic anhydride formed by a catalytic vapor phase oxidation of naphthalene. An extraction of naphthoquinone is carried out with a chain or cyclic saturated hydrocarbon at 60.degree. to 110.degree. C. under the condition adjusting pH to 1.2 to 5 and substantially dissolving phthalic acid in the aqueous phase and leaving resinous materials as a bottom.

Abstract: Disclosed is a process for the preparation of quinhydrones by the catalytic oxidation of aromatic diols with a peroxide in the presence of a catalyst system comprising a cerium carboxylate and a cupric carboxylate.

Abstract: A method for the preparation of a mixture of fused ring quinone type compounds from lignin and lignin-derived substances. The mixture of fused ring quinone compounds has been found useful in the wood pulping process as an accelerator in the degradation and separation of wood lignin from the other principal wood constituents, cellulose and hemicellulose.

Abstract: A catalyst for use in vapor phase oxidation of naphthalene into 1,4-naphthoquinone is dislosed. The catalyst which is supported on an inert carrier material is represented by the formula:(V)a(K)b(S)c(Fe)d(Sn)e(X)f(O)gwhere V, K, S, Fe, Sn and O stand for vanadium, potassium, sulfur, iron, tin and oxygen, respectively; X stands for at least one element such as silicon, titanium or aluminum which serves as a carrier in the form of oxide; and a, b, c, d, e, f and g are the atomic fractions of the respective elements wherein the ratio of a:b:c:d:e:f=10:10-100:5-100:0.1-10:0.05-10:10-300. Using the above catalyst the vapor phase oxidation can be effected at a relatively low temperature of not higher than 500.degree. C., usually not higher than 420.degree. C., resulting in the formation of 1,4-naphthoquinone in a high yield and with a high selectivity.

Abstract: Hydrolyzable substrates comprise blocked moieties which, when cleaved from the substrate during hydrolysis, provide electron transfer agents. The released electron transfer agents can be recycled between a reductant and a reducible compound that upon reduction provides a detectable species. Alternatively, they can be recycled between an oxidant and an oxidizable compound that upon oxidation provides a detectable species. These substrates are useful in analytical compositions, elements and methods for the determination of hydrolytic analytes, such as hydrolytic enzymes or biological cells containing such enzymes.