Abstract: Polydentate substituted pyrrole based chelants, metal complexes containing the same, olefin polymerization catalyst compositions, and polymerization processes using the same.

Abstract: Chiral ligands and transition metal complexes based on such chiral ligands useful in asymmetric catalysis are disclosed. The chiral ligands include (R,S,S,R)-DIOP*. The ruthenium complex reduces enamide to the corresponding amine with up to 99% enantioselectivity. The transition metal complexes of the chiral ligands are useful in asymmetric reactions such as asymmetric hydrogenation, hydride transfer, hydrosilylation, hydroboration, hydrovinylation, hydroformylation, hydrocarboxylation, isomerization, allylic alkylation, cyclopropanation, Diels-Alder reaction, Heck reaction, isomerization, Aldol reaction, Michael addition and epoxidation reactions. The chiral ligands are of the formula the identittes of the R, R? and Y groups are defined herein.

Abstract: Disclosed are a new class of a polyphosphazene-platinum(II) conjugate antitumor agent having high tumor tissue selectivity due to its enhanced permeability and retention effect to tumor tissues, and a preparation method thereof: wherein x represents the number of the ethylene oxide repeating unit and is 7, 12 or 16; y is 0, 1 or 2; z represents molar content of polyethylene glycol in the range of 0.5-1.5; n represents degree of polymerization of polyphosphazene in the range of 30-100; and A-A represents a diamine.

Abstract: One aspect of the present invention relates to novel ligands for transition metals. A second aspect of the present invention relates to the use of catalysts comprising these ligands in transition metal-catalyzed carbon-heteroatom and carbon-carbon bond-forming reactions. The subject methods provide improvements in many features of the transition metal-catalyzed reactions, including the range of suitable substrates, reaction conditions, and efficiency.

Abstract: The invention relates to a process for the preparation of 15-pentadecanolide by hydrogenating 15-pentadecenolide and to its use.

Abstract: Disclosed herein are processes for polymerizing ethylene, acyclic olefins, and/or selected cyclic olefins, and optionally selected olefinic esters or carboxylic acids, and other monomers. The polymerizations are catalyzed by selected transition metal compounds, and sometimes other co-catalysts. Since some of the polymerizations exhibit some characteristics of living polymerizations, block copolymers can be readily made. Many of the polymers produced are often novel, particularly in regard to their microstructure, which gives some of them unusual properties. Numerous novel catalysts are disclosed, as well as some novel processes for making them. The polymers made are useful as elastomers, molding resins, in adhesives, etc.

Abstract: A process for producing organic substituted aromatic or heteroaromatic compounds including biaryl and biheteroaryl compounds in a two-step reaction. In the first step, the aromatic or heteroaromatic compound is borylated in a reaction comprising a borane or diborane reagent (any boron reagent where the boron reagent contains a B—H, B—B or B—Si bond) and an iridium or rhodium catalytic complex. In the second step, a metal catalyst catalyzes the formation of the organic substituted aromatic or heteroaromatic compound from the borylated compound and an electrophile such as an aryl or organic halide, triflate (OSO2CF3), or nonaflate (OSO2C4F9). The steps in the process can be performed in a single reaction vessel or in separate reaction vessels. The present invention also provides a process for synthesis of complex polyphenylenes starting from halogenated aromatic compounds.

Abstract: A family of novel hetrocyclic-amide type catalyst precursors useful for the polymerization of olefins, such as ethylene, higher alpha-olefins, dienes, and mixtures thereof.

Abstract: 3,3?-Substituted chiral biaryl phosphine and phosphinite ligands and metal complexes based on such chiral ligands useful in asymmetric catalysis are disclosed. The metal complexes are useful as catalysts in asymmetric reactions, such as, hydrogenation, hydride transfer, allylic alkylation, hydrosilylation, hydroboration, hydrovinylation, hydroformylation, olefin metathesis, hydrocarboxylation, isomerization, cyclopropanation, Diels-Alder reaction, Heck reaction, isomerization, Aldol reaction, Michael addition, epoxidation, kinetic resolution and [m+n] cycloaddition. The metal complexes are particularly effective in Ru-catalyzed asymmetric hydrogenation of beta-ketoesters to beta-hydroxyesters and Ru-catalyzed asymmetric hydrogenation of enamides to beta amino acids.

Abstract: By means of a liquid crystalline polyester resin composition containing 100 parts by weight of a liquid crystalline polyester forming an anisotropic melt phase, and not less than 0.01 part by weight and not more than 0.2 part by weight of at least one phosphite compounds defined by the formula (I): a liquid crystalline polyester resin composition capable of producing molded products having excellent thermal stability under high temperatures without causing occurrence of blister in the molded products even in the course of soldering.

Abstract: The invention relates to an ionic compound corresponding to the formula [R1X1(Z1)—Q?—X2(Z2)—R2]m Mm+ in which Mm+ is a cation of valency m, each of the groups Xi is S?Z3, S?Z4, P—R3 or P—R4; Q is N, CR5, CCN or CSO2R5, each of the groups Zi is ?O, ?NC?N, ?C(C?N)2, ?NS (?Z)2R6 or ?C[S(?Z)2R6]2, each of the groups Ri, is Y, YO—, YS—, Y2N— or F, Y represents a monovalent organic radical or alternatively Y is a repeating unit of a polymeric frame. The compounds are useful for producing ion conducting materials or electrolytes, as catalysts and for doping polymers.

Abstract: A new ligands that include a benzene ring in the backbone can be combined with a metal or metal precursor compound or formed into a metal-ligand complex catalyze a number of different chemical transformations, including olefin polymerization reactions. The ligands, complexes formed with the ligands and compositions including the ligands are useful catalysts, depending on the reaction.

Abstract: Phosphonites I of the formula 1 or 2 1

Abstract: This invention relates to a compound represented by the formula: 1

Abstract: Metal compounds of the formula I, where M is selected from among Ni and Pd in the oxidation state +II can be used for the polymerization or copolymerization of olefins. Supported catalysts for the polymerization and copolymerization of olefins can be obtained by application of one or more of the above-described ionic metal compounds to a support.

Abstract: P-chiral bisphospholane ligands and methods for their preparation are described. Use of metal/P-chiral bisphospholane complexes to catalyze asymmetric transformation reactions to provide high enantiomeric excesses of formed compounds is also described.

Abstract: A light-emitting device comprising a pair of electrodes, and organic compound layers comprising a light-emitting layer provided in between the electrodes, wherein at least one of the organic compound layers comprises a compound having a transition metal atom-phosphorus atom bond.

Abstract: A metal compound obtained by a process comprising the step of contacting, in a specific ratio, a compound represented by the formula M1L1r, a compound represented by the formula R1s-1TH, and a compound represented by the formula R24-nJ(OH)n; a catalyst component for addition polymerization comprising the metal compound; a catalyst for addition polymerization using the catalyst component; and a process for producing an addition polymer using the catalyst.

Abstract: The invention relates to copper complexes of phosphorus compounds, to a process for their preparation and to their use in catalytic coupling reactions.

Abstract: Stable rare earth tris (organophosphate) solutions comprise a rare earth tris (organophosphate) and a hydrocarbon solvent. From about 2% to about 10% rare earth element, preferably from about 3% to about 8%, is present in the solutions. The rare earth tris (organophosphate) solutions are stable from precipitation of the rare earth tris (organophosphate) for at least about fifteen (15) days, preferably for at least about twenty (20) days and most preferably at least about thirty (30) days. A process for preparing these solutions is described herein. A stabilizing additive, acid, glycol or mixtures thereof, is utilized to inhibit precipitation. The molar ratios of free acid, glycol and/or water to the rare earth element are controlled to inhibit precipitation.

Abstract: Active vanadium/phosphorus mixed oxide catalyst for the conversion of non-aromatic hydrocarbons, e.g., n-butane, into maleic anhydride. The catalyst is prepared from the catalyst precursor, that is, prepared by the reaction of a source of vanadium in an organic medium in the presence of a phosphorus source. The organic medium is (a) isobutyl alcohol or a mixture of isobutyl alcohol and benzyl alcohol and (b) a polyol. The catalyst precursor is transformed into the active catalyst by an activation process that includes a heat treatment that includes applying a temperature of up to 600° C.

Abstract: Disclosed are organometallic compounds derived from Groups VIIb, VIII, IX, and X metals useful as precursors for the formation of metal containing powders and for the chemical deposition of the metals on substrates, particularly for the chemical vapor deposition of metal films suitable for the manufacture of electronic devices. Methods for their use are also disclosed.

Abstract: Novel phosphites have the formula I P(O—R1)x(O—R2)y(O—R3)z(O—R4)p  I where R1: aromatic radical having a C1-C18-alkyl substituent in the o position relative to the oxygen atom which connects the phosphorus atom to the aromatic system, or having an aromatic substituent in the o position relative to the oxygen atom which connects the phosphorus atom to the aromatic system, or having an aromatic system fused on in the o position relative to the oxygen atom which connects the phosphorus atom to the aromatic system, R2: aromatic radical having a C1-C18-alkyl substituent in the m position relative to the oxygen atom which connects the phosphorus atom to the aromatic system, or having an aromatic substituent in the m position relative to the oxygen atom which connects the phosphorus atom to the aromatic system, or having an aromatic system fused on in the m position relative to the oxygen atom which connects the phosphorus atom to the aromatic system, where the aromatic radical

Abstract: A series of novel late transition metal catalysts for olefin oligomerization have been invented. The catalysts demonstrate high activity and selectivity for linear &agr;-olefins.

Abstract: The invention relates to new (pre)catalysts of ruthenium complexes of formula 1, 1

Abstract: P-chiral bisphospholane ligands and methods for their preparation are described. Use of metal/P-chiral bisphospholane complexes to catalyze asymmetric transformation reactions to provide high enantiomeric excesses of formed compounds is also described.

Abstract: Disclosed is a new catalyst composition comprising a bimetallic Co—Fe catalyst, optionally complexed with a ligand selected from a N-heterocycle, phosphine, or porphorine ligand, that provides a lower cost alternative for the one step synthesis of 1,3-propanediol (1,3-PDO) from ethylene oxide and synthesis gas. For example, a catalyst containing cobalt carbonyl: iron carbonyl with no ligand, or a catalyst containing a cobalt carbonyl: octaethylporphine iron acetate provide moderate yields of 1,3-PDO in a one step synthesis under mild conditions.

Abstract: The invention is concerned with new phosphine ligands of formula I 1

Abstract: The present invention relates to chromium(III) complexes defined by following formula: 1

Abstract: Novel complexes having the formula (I) are disclosed, wherein M is a Group 6 metal and T is its oxidation state; X represents an atom or group covalenty or ionically bonded to M; b is the valency of the atom or group X; L is a group datively bound to M, and n is from 0 to 4; Z is oxygen or sulphur; A1 to A3 are each independently N or P or CR, with the provisio that at least one is CR; R1 is a polycyclic hydrocarbyl group; Q is CR5, PR5R5 or N; each R and R5 to R7 are all independently selected from hydrogen, halogen, hydrocarbyl, substituted hydrocarbyl, heterohydrocarbyl or SiR′3 where each R′ is independently selected from hydrogen, halogen, hydrocarbyl, substituted hydrocarbyl, heterohydrocarbyl, substituted heterohydrocarbyl, and any two or more of each R and R5 to R7 may be linked to form cyclic substituents. These complexes have utility as catalysts for the polymerisation of 1-olefins.

Abstract: The invention relates to new compounds of the formula, wherein R and R1 are each independently hydrogen, a linear or branched C1-40 alkyl, C2-40 alkenyl or C2-40 alkynyl group, an aryl or C1-40 alkylaryl group or an optionally complex metal ion Mn+/n wherein n is an integer from 1 to 8; the free valences of the silicate oxygen atoms are saturated by one or more of: silicon atoms of other groups of the formula, hydrogen, a linear or branched C1-12alkyl group or by cross-linking bridge members R3qM1(OR2)mOk/2 or Al(OR2)3-pOp/2 or R3Al(OR2)2-rOr/2; where M1 is Si or Ti; R2 is linear or branched C1-12 alkyl group; and R3 is a linear or branched C1-6 alkyl group; k is an integer from 1 to 4 and q and m are integers from 0 to 2; such that m+k+q=4; and p is an integer from 1 to 3; and r is an integer from 1 to 2; or other known oxo metal bridging systems; x, y and z are integers such that the radio of x:y+z, varies from 0.

Abstract: The invention relates to novel phosphane ligands of formula (Ia) and (Ib): (adamantyl)nP(alkyl)m(1a); (adamantyl)o(Alkyl)qP (alkylen′)P(adamantyl)r(alkyl)s (1b), wherein adamantyl represents an adamantyl radical (IIa, IIb) bonded to the phosphorous atom in position 1 or 2. The invention also relates to the production and use of the above-mentioned ligands in the presence of transitional metal compounds of the 8th. Subgroup of PSE for catalytic reactions, particularly for the refining of halogen aromatics for producing aryl olefins, dienes, diarylene, benzoic acid and acrylic acid derivatives, aryl alkanes and also amines.

Abstract: The application relates to diazaphospholidine compounds of Formula 1 and Formula 2: where: A and B are independently selected from C(R22R23) and C(R22R23)C(R24R25); R1, R2, R3, R4, R18, R19, R20, R21, R22, R23, R24 and R25 each may not be present and each may be independently selected from H, halide —OH, —SO2R26 (where R26 is selected from a group as defined for R22, R23, R24 and R25), —SH, —NO2, —NH2, ═O, ═S, straight chain, branched chain, cyclic, saturated, non-saturated, substituted or non-substituted alkyl, hydroalkyl, carboalkyl, alkoxy, amino, alkenyl, aryl and —CH2 Ar (where Ar is aryl or substituted aryl), preferably containing 1 to 6 carbons, or a silane containing 1 to 6 silicon atoms, wherein, where an R1, R2, R3, R4, R18, R19, R20, R21, R22, R23, R24 and/or R25 group is not present an unsaturated bond is formed; R5 and R17 are selected from H, —NH2, —OH, halide or a substituted or non-substituted strai

Abstract: A phosphine compound of formula (1) and a phosphine compound of formula (2) a transition metal complex having the phosphine compound as a ligand and a catalyst for asymmetric hydrogenation including the transition metal complex.

Abstract: A novel process for preparation of alkenylphosphine oxides or alkenylphosphinic acid esters provided by which the objective compounds can be easily, safely and efficiently synthesized and easily separated and purified with little formation of by-products. Specifically, a process of conducting the addition reaction of an easily available secondary phosphine oxide or hydrogen phosphinic acid ester with an acetylene compound with a catalyst containing a Group 9 or 10 metal of the periodic table to thereby obtain the corresponding alkenylphosphine oxide or alkenylphosphinic acid ester.

Abstract: Chelating monomers and fluoride-releasing compositions are disclosed that may be incorporated into dental composite restorative materials or other dental materials, to produce materials with high fluoride release rates, and high fluoride recharge capability. Such resins may be used in dental restorative materials to help reduce the level of dental caries in patients, particularly the level of caries occurring on the margins of the restorative materials.

Abstract: The invention provides metallocene catalyst systems for the controlled polymerization of alkenes to a wide variety of polyolefins and olefin coplymers. Catalyst systems are provided that specifically produce isotactic, syndiotactic and steroblock polyolefins. The type of polymer produced can be controlled by varying the catalyst system, specifically by varying the ligand substituents. Such catalyst systems are particularly useful for the polymerization of polypropylene to give elastomeric polypropylenes. The invention also provides novel elastomeric polypropylene polymers characterized by dyad (m) tacticities of about 55% to about 65%, pentad (mmmm) tacticities of about 25% to about 35%, molecular weights (MW) in the range of about 50,000 to about 2,000,000, and have mmrm+rrmr peak is less than about 5%.

Abstract: A process for stabilizing a fluorophosphite ligand in a hydroformylation reaction mixture having an &agr;-olefin, hydrogen, carbon monoxide and a catalyst composition having a combination of a rhodium containing compound and one or more fluorophosphite compounds having the general formula: wherein R1 and R2 are hydrocarbyl radicals which contain a total of up to about 40 carbon atoms, the process includes the step of adding to the reaction mixture an epoxide in a sufficient amount to reduce the degradation of the fluorophosphite ligand.

Abstract: A new and more efficient synthesis of combretastatin A-3 (2a) was completed (8.4% overall yield) starting front methyl gallate and isovanillin with aldehyde 5 and phosphonium salt 8 as key intermediates. Conversion of combretastatin A-3 (2a) to a series of diphosphate prodrugs (IOa-IOl) containing selected anions was achieved.

Abstract: A complex suitable for the polymerization of l-olefins is disclosed, having the Formula A wherein M is a transition metal, lanthanide or actinide; X represents an atom or group covalently or ionically bonded to the transition metal M; b is the valency of the atom or group X; Z1 is N or P; Z2 is N, P, N−, P−or NR5; Z3 is one of N, P, O, S, NHR3, NR3R4, OH, OR3, SH, SR3, PHR3, PR3R4, (NR3)−, O−, S−, (PR3)−, P(R3R4)O, NR3 or PR3 to the proviso that one of Z2 and Z3 is anionic; T is the oxidation state of the transition metal M when both Z2 or Z3 are neutral, and is one less than the oxidation state of M when one of Z2 or Z3 is anionic; A and B are independently hydrocarbyl, substituted hydrocarbyl, heterohydrocarbyl or substituted heterohydrocarbyl, and may together with Z2 form part of a heterocyclic substituent; B may be joined to Z3 by either a single or a double bond; R1 to R5 are each independently selected from hydrogen, halogen, hydrocarbyl, substitute

Abstract: New ligands and compositions with bridged bis-aromatic ligands are disclosed that catalyze the polymerization of monomers into polymers. These catalysts with metal centers have high performance characteristics, including higher comonomer incorporation into ethylene/olefin copolymers, where such olefins are for example, 1-octene, propylene or styrene. The catalysts also polymerize propylene into isotactic polypropylene.

Abstract: A process for the hydrogenation, using molecular hydrogen (H2), of a catalytic system, wherein the catalytic system comprises a base and a complex of formula; (II) wherein Y represents simultaneously or independently a hydrogen or halogen atom, a hydroxy group, or an alkoxy, carboxyl or other anionic radical, and N2P2 is a tetradentate diimine-diphosphino ligand.

Abstract: One aspect of the present invention relates to novel ligands for transition metals. A second aspect of the present invention relates to the use of catalysts comprising these ligands in transition metal-catalyzed carbon-heteroatom and carbon-carbon bond-forming reactions. The subject methods provide improvements in many features of the transition metal-catalyzed reactions, including the range of suitable substrates, reaction conditions, and efficiency.

Abstract: This invention is a process for synthesizing aliphatic 1,3-diols in one step by hydroformylation and hydrogenation of oxirane, carbon monoxide, and hydrogen employing a catalyst comprising a cobalt carbonyl compound and a cocatalyst metal compound ligated with a ligand in a ligand to cocatalyst metal atom molar ratio in the range of 0.2:1.0 to 0.6:1.0, optionally in the presence of a promoter, where recovery of product is preferably accomplished via water extraction of a diol rich phase from the bulk reaction mixture. The process modifications can, particularly in combination, be beneficial with respect to product recovery, catalyst recycle, and overall economics of a one-step process for producing aliphatic 1,3-diols.

Abstract: The present invention relates to compounds in which a transition metal is complexed with two ligand systems and the two systems are reversibly bonded together by at least one bridge consisting of a donor and an acceptor, at least one substituent on the acceptor group being a fluorinated aryl radical, to the use of these compounds as catalysts and to a process for the polymerization of olefins.

Abstract: The invention relates to novel transition metal complexes of the formula (I) 1

Abstract: 3,3′-Substituted chiral biaryl phosphine and phosphinite ligands and metal complexes based on such chiral ligands useful in asymmetric catalysis are disclosed. The metal complexes are useful as catalysts in asymmetric reactions, such as, hydrogenation, hydride transfer, allylic alkylation, hydrosilylation, hydroboration, hydrovinylation, hydroformylation, olefin metathesis, hydrocarboxylation, isomerization, cyclopropanation, Diels-Alder reaction, Heck reaction, isomerization, Aldol reaction, Michael addition, epoxidation, kinetic resolution and [m+n] cycloaddition. The metal complexes are particularly effective in Ru-catalyzed asymmetric hydrogenation of beta-ketoesters to beta-hydroxyesters and Ru-catalyzed asymmetric hydrogenation of enamides to beta amino acids.

Abstract: Compounds and metal complexes comprising a polycyclic, fused ring ligand or inertly substituted derivative thereof having up to 60 atoms other than hydrogen, said ligand comprising at least: (1) a cyclopentadienyl ring, (2) a 6, 7, or 8 membered ring other than a 6-carbon aromatic ring, and (3) an aromatic ring, with the proviso that said 6, 7, or 8 membered ring (2), is fused to both the cyclopentadienyl ring (1), and the aromatic ring (3), polymerization catalysts, a process to prepare the novel compounds and complexes, and olefin polymerization processes using the same are disclosed.

Abstract: The present invention provides a non-metallocene catalyst comprising a complex having one or more ligands coordinated a transition metal. The catalyst contains substituents bonded to the transition metal through a heteroatom such as oxygen or sulfur. Furthermore, the complex includes a Group 3 to 10 transition or lanthanide metal and one or more anionic or neutral ligands in an amount that satisfies the valency of the metal such that the complex has a net zero charge. The present invention also discloses a method for preparing the catalyst and polymerizing olefins utilizing the catalyst of the present invention.

Abstract: The invention relates to the bisphosphites of the general formula(I), wherein R1, R2, R3, $4 R5 R6 represent H, an aliphatic, alicyclic, aliphatic-alicyclic, heterocyclic, aliphatic-heterocyclic, aromatic, aliphatic-aromatic hydrocarbon group with 1 to 50 carbon atoms, F, Cl, Br, I, —OR7, —COR7, —CO2R7, —CO2M, —SR7, —SO2R7, —SOR7, —SO3R7, —SO3M, —SO2NR7R8, NR7R8, N═CR7R8, NH2, wherein R1 to R6 are the same or different and can be covalently linked with each other, R7, R8 represent H, a substituted or unsubstituted, aliphatic or aromatic hydrocarbon group with 1 to 25 carbon atoms, which are the same or different, M represents an alkali metal, alkaline earth metal, ammonium, phosphonium ion; Q represents a bivalent, aliphatic alicyclic, aliphatic-alicyclic, heterocyclic, aromatic, aliphatic-aromatic hydrocarbon group with 1 to 50 carbons atoms, W, X represent aliphatic, alicyclic, aliphatic-alicyclic, heterocyclic, aliphatic-heterocyclic, aromati