Carbonyl Attached Directly Or Indirectly To Silicon By Nonionic Bonding Patents (Class 556/436)
- Silicon and the carbon of the -COO- group are bonded directly to the same hydrocarbon group (Class 556/438)
- Silicon and the oxy of the -COO- group are bonded directly to the same hydrocarbon group (Class 556/440)
- Carbocyclic ring having silicon as part of one substituent and the -COO- as part of another substituent (Class 556/441)
- Silicon is bonded directly to the oxy of the -COO- group (Class 556/442)
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Patent number: 4661611Abstract: Polyfunctional acyl silanes of the formula ##STR1## are disclosed as novel crosslinking agents. Composition and processes involving the same are also disclosed.Type: GrantFiled: December 6, 1985Date of Patent: April 28, 1987Assignee: Fuji Photo Film Co., Ltd.Inventors: Subhash C. Narang, Richard Vicari, Juesheng Gu
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Patent number: 4645844Abstract: Novel and known functionally substituted phenoxyalkyl-, thiophenoxyalkyl- and pyridyloxyalkylsilanes are prepared by reacting substantially equimolar amounts of an alkali- or alkaline earth metal phenoxide, thiophenoxide or pyridyloxide with a haloalkylsilane under anhydrous conditions using a dipolar, aprotic solvent in combination with a liquid hydrocarbon.Type: GrantFiled: July 20, 1983Date of Patent: February 24, 1987Assignee: M&T Chemicals Inc.Inventors: Abe Berger, Irwin B. Silverstein
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Patent number: 4644068Abstract: Bicyclo[3.3.0]octenylaldehyde derivatives represented by the formula: ##STR1## wherein R.sup.1 is a substituent selected from the group consisting of a hydrogen atom and a protective group of a hydroxy group;R.sup.2 is a substituent selected from the group consisting of --CH.sub.2 OR.sup.5, ##STR2## where R.sup.5 is a substituent selected from the group consisting of a hydrogen atom and a protective group of a hydroxy group,R.sup.6 is a substituent selected from the group consisting of an alkyl group, an alkenyl group and an alkynyl group, said substituent being straight, branched or cyclic and having 5 to 10 carbon atoms,X is a substituent selected from the group consisting of a vinylene group and an acetylene group, andR.sup.7 is a substituent selected from the group consisting of an alkyl, an alkenyl group, and an alkynyl group, said substituent being straight, branched or cyclic and having 5 to 10 carbon atoms; andR.sup.Type: GrantFiled: August 17, 1984Date of Patent: February 17, 1987Assignee: Sagami Chemical Research CenterInventors: Masakatsu Shibasaki, Mikiko Sodeoka, Yuji Ogawa
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Patent number: 4609668Abstract: The invention provides novel .alpha.-(ethynyl substituted phenyl)-.alpha.-hydrocarbyl-1H-azole-ethanols wherein the azole group is 1,2,4-triazol-1-yl or imidazol-1-yl, the ethynyl group is unsubstituted or substituted and the phenyl group may bear an additional substituent and ethers thereof, which are useful as fungicides.Type: GrantFiled: August 24, 1984Date of Patent: September 2, 1986Assignee: Sandoz Ltd.Inventors: Fritz Schaub, Rupert Schneider
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Patent number: 4605758Abstract: Pharmaceutically useful optically active .alpha.-arylalkanoic acids or esters, ortho esters, or amides thereof are stereoselectively prepared by contacting an aryl magnesium Grignard reagent with an optically active .alpha.-substituted acyl halide to form the optically active aryl .alpha.-substituted alkyl ketone, which is ketalized and rearranged to the desired optically active .alpha.-arylalkanoic acid or the corresponding ester, ortho ester or amide. In an alternate embodiment, the aryl .alpha.-substituted alkyl ketone is reduced to the corresponding alkanol, which is rearranged to the .alpha.-arylalkanal. The alkanal so produced is converted to the desired optically active .alpha.-arylalkanoic acid by conventional methods.Type: GrantFiled: April 23, 1984Date of Patent: August 12, 1986Assignee: Syntex Pharmaceuticals International Ltd.Inventor: George C. Schloemer
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Patent number: 4604477Abstract: A method is provided for making silylaroylhalides such as chlorodimethylsilylbenzoyl chloride. Reaction is effected between substantially equivalent amounts of a polyhaloacyl aromatic compound, for example, terephthaloyl chloride and a polyhalopolysilane such as dichlorodisilane in the presence of a palladium catalyst.Type: GrantFiled: March 29, 1985Date of Patent: August 5, 1986Assignee: General Electric CompanyInventor: Jonathan D. Rich
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Patent number: 4595776Abstract: The invention is directed to a process and intermediates for the preparation of 1.alpha.,25-dihydroxyergocalciferol as well as substantially pure and crystalline 1.alpha.,25-dihydroxyergocolciferol. The end-product 1.alpha.,25-dihydroxyergocalciferol is useful in the treatment of disease states which are characterized by insufficient amounts of 1.alpha., 25-dihydroxycholecalciferol.Type: GrantFiled: December 17, 1984Date of Patent: June 17, 1986Assignee: Hoffmann-La Roche Inc.Inventors: Enrico G. Baggiolini, Andrew D. Batcho, Alfred Boris, Milan R. Uskokovic
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Patent number: 4585885Abstract: A silyl-enol ether of the formula ##STR1## wherein n stands for the number and X stands for a group ##STR2## or n stands for the number 1 and X stands for the 6,11-dimethylhexadeca-2,4,6,8,10,12,14-heptaene-2,15-diyl group, the symbols R.sup.1 have the same or different significances and denote alkyl groups, and the symbol R.sup.2 represents a trialkylsiloxy group --OSi(R.sup.1).sub.3 or an ether group,is oxidized with percarboxylic acid and, if desired, the resulting .alpha.-siloxy ketone is hydrolyzed to an .alpha.-hydroxy ketone. This process is especially suitable for the manufacture of astaxanthin.Type: GrantFiled: August 19, 1983Date of Patent: April 29, 1986Assignee: Hoffmann-La Roche Inc.Inventors: Kurt Bernhard, Robert K. Muller, Robert Spruijtenburg
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Patent number: 4574153Abstract: Antibacterial activity is exhibited by compounds having the formula ##STR1## and pharmaceutically acceptable salts thereof, wherein, R.sub.1 is an acyl group derived from a carboxylic acid;R.sub.2 is hydrogen, methoxy, or formamido ##STR2## and one of R.sub.3 and R'.sub.3 is hydrogen and the other is ##STR3## and R.sub.4 is hydrogen alkyl, substituted alkyl, phenyl, substituted phenyl, phenylalkyl or (substituted phenyl)alkyl.Type: GrantFiled: March 1, 1985Date of Patent: March 4, 1986Assignee: E. R. Squibb & Sons, Inc.Inventors: David Kronenthal, Paula L. Kuester, William H. Koster
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Patent number: 4565886Abstract: Ethynyl and substituted ethynyl-terminated polysulfones and a process for preparing the same are disclosed. These polysulfones are thermally cured to induce cross-linking and chain extension, producing a polymer system with improved solvent resistance and use temperatures. Also disclosed are substituted 4-ethynylbenzoyl chlorides as precursors to the substituted ethynyl-terminated polysulfones and a process for preparing the same.Type: GrantFiled: August 30, 1983Date of Patent: January 21, 1986Assignee: The United States of America as represented by the Administrator of the National Aeronautics and Space AdministrationInventor: Paul M. Hergenrother
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Patent number: 4554363Abstract: Process for the preparation of bicyclic ketones containing blocked hydroxy groups, of general Formula I ##STR1## wherein R.sub.1 is the residues --CH.sub.2 OR.sub.2 wherein R.sub.2 means benzyl, dimethyl-tert-butylsilyl, diphenyl-tert-butylsilyl, dimethylphenylsilyl, tribenzylsilyl, or tetrahydropyranyl, ##STR2## with R.sub.2 having the meanings given above, R.sub.4 meaning hydrogen or methyl, and R.sub.5 meaning a straight-chain or branched-chain, saturated or unsaturated alkyl residue which can contain fluorine, chlorine, 1,2-methylene, 1,1-trimethylene, or methoxy substitutents, or a CH.sub.2 --X-Aryl residue with X meaning CH.sub.2 or O and Aryl meaning phenyl or a heterocyclic residue, which residues can be substituted by methyl, methoxy, fluorine, chlorine, bromine, or trifluoromethyl, or ##STR3## with the meanings for R.sub.2, R.sub.4, and R.sub.5 as indicated above, and R.sub.3 having the meanings set forth for R.sub.2, it being possible for R.sub.3 to be identical to R.sub.2 or different from R.sub.Type: GrantFiled: June 23, 1983Date of Patent: November 19, 1985Assignee: Schering AktiengesellschaftInventor: Helmut Vorbrueggen
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Patent number: 4536265Abstract: An organopolysiloxane photoinitiator having an average of at least two siloxane units, of which at least an average of one siloxane unit per organopolysiloxane molecule has the formula:X.sub.a R.sub.b SiO.sub.(4-a-b)/2wherein a is an integer of 1-3, b is a integer of 0-2 and a plus b equals 1-3; R is C.sub.1 -C.sub.10 hydrocarbyl or halogen substituted C.sub.1 -C.sub.10 hydrocarbyl; and X is substituted acetophenone photomoiety of the formula: ##STR1## where R.sup.1 is any substitutent which will not interfere with hydrosilation, n is an integer between 0 and 4; R.sup.2 is organosilyl substituted alkyl or alkenyl; R.sup.3 is H, alkyl or aryl; and R.sup.4 is a divalent hydrocarbon group having between 2 and 10 carbon atoms.The silicones are prepared by hydrosilation of the corresponding olefinically or acetylenically .alpha.,.alpha.-dialkenylacetophenones or .alpha.,.alpha.-dialkynylacetophenones.Type: GrantFiled: April 19, 1984Date of Patent: August 20, 1985Assignee: Loctite CorporationInventors: Louis F. Fabrizio, Samuel O. S. Lin, Anthony F. Jacobine
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Patent number: 4534838Abstract: An organopolysiloxane photoinitiator having an average of at least two siloxane units, of which at least an average of one siloxane unit per organopolysiloxane molecule has the formula:X.sub.a R.sub.b SiO(.sub.4-a-b)/2 (I)wherein a is an integer of 1-3, b is an integer of 0-2 and a plus b equals 1-3; R is C.sub.1 -C.sub.10 hydrocarbyl or halogen substituted C.sub.1 -C.sub.10 hydrocarbyl; and X is a substituted acetophenone photomoiety selected from: ##STR1## where R.sup.1 is any substituent which will not interfere with hydrosilation, n is an integer between 0 and 5 in formulas (II), (IIa), (III), (IIIa), (IV) and (IVa) and between 0 and 4 in formula (III) and (IIIa); m is 0 or 1; R.sup.2 is alkyl or substituted alkyl; R.sup.3 is H, alkyl or aryl; R.sup.4 is a divalent hydrocarbon group having between 2 and 10 carbon atoms or an alkylene oxy alkylene group; R.sup.Type: GrantFiled: September 27, 1984Date of Patent: August 13, 1985Assignee: Loctite CorporationInventors: Samuel Q. S. Lin, Anthony F. Jacobine
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Patent number: 4525586Abstract: The present specification provides novel analogs of carbacyclin (CBA.sub.2), 6a-carba-prostacyclin (6a-carba-PGI.sub.2), which have pronounced prostacyclin-like pharmacological activity, e.g., as platelet anti-aggregatory agents. Specifically the novel chemical analogs of CBA.sub.2 are those substituted by fluoro (C-5), alkyl (C-9), interphenylene (C-5), methano (C-6a,9), and an additional (olefinic) valence bond (C-6a,9). Further provided are benzindene analogs of CBA.sub.2 and substituted forms thereof, i.e., 9-deoxy-2', 9-methano (or 2', 9-methano)-3-oxa-4,5,6-trinor-3,7-(1',3'-interphenylene)-PGF.sub.1 compounds. Also provided are a variety of novel chemical intermediates, e.g., substituted bicyclo[3.3.0]octane intermediates, and chemical process utilizing such intermediates which are useful in the preparation of the novel CBA.sub.2 analogs.Type: GrantFiled: September 19, 1983Date of Patent: June 25, 1985Assignee: The Upjohn CompanyInventor: Paul A. Aristoff
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Patent number: 4520160Abstract: Siloxane-oxyalkylene block copolymer compositions are prepared by a hydrosilylation reaction, using a saturated higher alcohol, such as isostearyl alcohol, as the reaction solvent. The reaction solvent need not be removed from the resulting block copolymer, particularly when the block copolymer is used as an emulsifier in personal care compositions.Type: GrantFiled: December 27, 1983Date of Patent: May 28, 1985Assignee: Dow Corning CorporationInventor: Paul L. Brown
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Patent number: 4505905Abstract: Certain 7-oxobicyclo[3.2.0] hept-2-en-2-carboxylic acids, esters, and salts thereof useful as antibacterial agents or as intermediates for antibacterial agents, and methods for making and using them.Type: GrantFiled: April 15, 1982Date of Patent: March 19, 1985Assignee: E. I. Du Pont de Nemours and CompanyInventors: George A. Boswell, Jr., Anthony J. Cocuzza
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Patent number: 4504646Abstract: Aliphatic aldehyde polymer containing at least one Si atom in its molecular chain is a positive type resist having a very high sensitivity to radiation such as electron beams, X-rays, ion beams, etc.Type: GrantFiled: November 9, 1983Date of Patent: March 12, 1985Assignee: Hitachi, Ltd.Inventors: Kazuo Nate, Takashi Inoue, Hitoshi Yokono
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Patent number: 4495360Abstract: A method is provided for making certain methoxy-substituted silyl benzophenones useful as ultraviolet light absorbing agents for silicone hardcoat formulations. The methoxy-substituted benzophenones have been found to more readily equilibrate into silicone hardcoat formulations without adversely affecting the shelf-life of the resulting formulation. The ultraviolet light absorbing agents are obtained by equilibrating a mixture of methanol and trialkoxysilyl-substituted benzophenone in the presence of an acid catalyst. The resulting UV stabilized silicon hardcoat formulations also provide silicone hardcoated plastic articles having improved thermoformability, resistance to abrasion, and environmental degradation.Type: GrantFiled: April 30, 1982Date of Patent: January 22, 1985Assignee: General Electric CompanyInventor: Blair T. Anthony
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Patent number: 4487944Abstract: New acetylenic and allenic carbinols of formula ##STR1## respectively, wherein symbol R stands for a trialkyl-silyl or a C.sub.1 to C.sub.6 alkyl radical, preferably a methyl, a tert-butyl or an isoamyl radical, or a group of formula ##STR2## wherein, when taken separately, each of symbols R.sup.1 and R.sup.2 represents a lower alkyl radical or, when taken together, R.sup.1 and R.sup.2 represent a tetramethylene group, are useful intermediates for the preparation of .beta.-damascenone.Type: GrantFiled: September 27, 1983Date of Patent: December 11, 1984Assignee: Firmenich, SAInventors: Karl-Heinrich Schulte-Elte, Bernard M/u/ ller
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Patent number: 4467082Abstract: Novel photosensitizers are disclosed which are particularly useful in photopolymerizable organopolysiloxane and silicone resins. The photosensitizers are themselves organopolysiloxanes which contain at least one silicon-bonded benzophenone-containing radical. Synthesis methods are disclosed for preparing these photosensitizers which employ, as starting materials, an alkenyloxy-substituted benzophenone and a silicone compound containing at least one silicon-bonded hydrogen atom.Type: GrantFiled: March 15, 1982Date of Patent: August 21, 1984Assignee: Dow Corning CorporationInventors: Akihiko Shirahata, Keiichi Kishimoto
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Patent number: 4448980Abstract: In an improved catalytic process for preparing trialkylsilyl ethers from trialkylsilyl compounds and carbonyl group-containing compounds, the improvement consisting of using an organic or inorganic bifluoride (HF.sub.2.sup..crclbar.) as the catalyst.Type: GrantFiled: September 22, 1983Date of Patent: May 15, 1984Assignee: E. I. Du Pont de Nemours and CompanyInventor: Dotsevi Y. Sogah
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Patent number: 4436924Abstract: There are provided ultraviolet light absorbing agents of the following general formula ##STR1## wherein: ##STR2## Y is H or OH, Z is H, OH, OQ or OW, where at least one Z is OH if Y is H;Q is --CH.sub.2 (CH.sub.2).sub.n Si(R.sub.2).sub.x (OR.sub.1).sub.y ; andW is --C.sub.m H.sub.2m+1 ;where x=0, 1 or 2, y=1, 2 or 3, x+y=3, R.sub.1 =alkyl or alkanoyl having 1 to 6 carbon atoms, R.sub.2 =alkyl having 1 to 6 carbon atoms, n=0, 1 or 2, and m=1 to 18. Also provided are organopolysiloxane protective coating compositions containing said ultraviolet light absorbing agents having unique utility for protecting transparent plastic articles.This invention relates to new, improved ultraviolet light absorbing agents, as well as to articles primed and thereafter coated with compositions containing such agents. The novel compounds of this invention are silanolreactive alkoxysilyl- or alkanoyloxysilylalkyl ether adducts of aromatic ultraviolet absorbing agents.Type: GrantFiled: September 23, 1982Date of Patent: March 13, 1984Assignee: General Electric CompanyInventors: Bruce A. Ashby, Siegfried H. Schroeter
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Patent number: 4431832Abstract: This invention relates to polymeric organosilicon compounds containing aryl radicals and to a method for improving the gliding or slipping properties of organic fibers treated therewith. The polymeric organosilicon compounds are represented by the formulaM.sub.a R.sub.b Si{[(OSiR.sub.2).sub.n D].sub.m (OSiR.sub.2).sub.n OSiR.sub.3-d M.sub.d }.sub.4-a-bin which R is hydrocarbon or substituted hydrocarbon radical, D represents radicals of the formula--X.sub.a A--X.sub.a (A--X.sub.a).sub.c --,X represents the groups: ##STR1## --NR'--, --O--, --S--, --SO.sub.2 --, --R"--, --NR'R", ##STR2## --OR"--, --SR"--, --SO.sub.2 R", where R' is hydrogen or R, R" is a bivalent aliphatic hydrocarbon radical, A is a bivalent or substituted bivalent aromatic hydrocarbon radical, M represents radicals of the formula--X.sub.a --A--X.sub.a (A--X.sub.a).sub.c H,a is 0 or 1, b is 0, 1 or 2, c is 0 or a number of from 1 to 5, m is 0 or a number of from 1 to 20, n is a number of from 1 to 1,000 with the proviso that at least one OSiP.Type: GrantFiled: August 24, 1982Date of Patent: February 14, 1984Assignee: Wacker-Chemie GmbHInventors: Peter Huber, Peter August, Helga Lampelzammer, Willi Primas
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Patent number: 4424392Abstract: Aldehyde containing hydrolyzable silane compositions of matter and a process for preparing same by hydroformylating an ethylenically unsaturated organic containing hydrolyzable silane.Type: GrantFiled: March 24, 1982Date of Patent: January 3, 1984Assignee: Union Carbide CorporationInventor: Herbert E. Petty
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Patent number: 4424374Abstract: Compounds of the general formula: ##STR1## wherein R.sup.1 represents a straight- or branched-chain alkyl group containing from 1 to 6 carbon atoms or a phenoxy or benzyl group, and pharmaceutically acceptable salts and esters thereof, possess pharmacological properties of use in the fields of mammalian reproduction and cardiovascular disease.Type: GrantFiled: March 13, 1981Date of Patent: January 3, 1984Assignee: May & Baker LimitedInventors: Michael P. L. Caton, Keith A. J. Stuttle
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Patent number: 4406764Abstract: Disclosed is a photo-curable epoxy resin composition which comprises an epoxy resin and a combination of an aluminum compound and an .alpha.-ketosilyl compound as a catalyst.Type: GrantFiled: January 22, 1982Date of Patent: September 27, 1983Assignee: Tokyo Shibaura Denki Kabushiki KaishaInventors: Syuzi Hayase, Takeo Ito
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Patent number: 4394518Abstract: This invention relates to polymeric organosilicon compounds containing aryl radicals and to a method for improving the gliding or slipping properties of organic fibers treated therewith. The polymeric organosilicon compounds are represented by the formulaM.sub.a R.sub.b Si{[(OSiR.sub.2).sub.n D].sub.m (OSiR.sub.2).sub.n OSiR.sub.3-d M.sub.d }4-a-bin which R is hydrocarbon or substituted hydrocarbon radical, D represents radicals of the formula--X.sub.a A--X.sub.a (A--X.sub.a).sub.c --,X represents the groups: ##STR1## where R' is hydrogen or R, R" is a bivalent aliphatic hydrocarbon radical, A is a bivalent or substituted bivalent aromatic hydrocarbon radical, M represents radicals of the formula--X.sub.a --A--X.sub.a (A--X.sub.a).sub.c H,a is 0 or 1, b is 0, 1 or 2, c is 0 or a number of from 1 to 5, d is 0 or 1, m is 0 or a number of from 1 to 20, n is a number of from 1 to 1,000 with the proviso that at least one OSiR.sub.2 -- unit and at least one X.sub.a --A--X.sub.Type: GrantFiled: December 31, 1979Date of Patent: July 19, 1983Assignee: Wacker-Chemie GmbHInventors: Peter Huber, Peter August, Helga Lampelzammer, Willi Primas
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Patent number: 4390660Abstract: There are provided ultraviolet light absorbing agents of the formula ##STR1## wherein: X is >C.dbd.O, or ##STR2## Y is H or OH; Z is H, OH, OQ or OW, where at least one Z is OH if Y is H;Q is --CONH(CH.sub.2).sub.3 Si(R.sub.2).sub.x (OR.sub.1).sub.y or --CONH(CH.sub.2).sub.3 Si(R.sub.2).sub.x (OCOR.sub.1).sub.y ; andW is --C.sub.m H.sub.2m+1 ;where x=0, 1 or 2, y=1, 2 or 3, x+y=3, R.sub.1 and R.sub.2, independently are each alkyl having 1 to 6 carbon atoms and m=1 to 18. Also provided are organopolysiloxane protective coating compositions containing said ultraviolet light absorbing agents having unique utility for protecting transparent plastic articles.Type: GrantFiled: December 9, 1981Date of Patent: June 28, 1983Assignee: General Electric CompanyInventor: Bruce A. Ashby
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Patent number: 4383122Abstract: An optically active or racemic .alpha.-hydroxyaldehyde represented by the general formula (2), ##STR1## wherein R.sub.1 represents a C.sub.6 -C.sub.14 aryl group, C.sub.1 -C.sub.10 alkyl group, C.sub.3 -C.sub.10 alkenyl group, C.sub.2 -C.sub.10 alkynyl group, C.sub.7 -C.sub.14 aralkyl group, or a group containing a functional group in the organic portion of said groups and R.sub.2 represents a C.sub.1 -C.sub.10 alkyl group, C.sub.2 -C.sub.10 alkenyl group, C.sub.2 -C.sub.10 alkynyl group, C.sub.7 -C.sub.14 aralkyl group, C.sub.6 -C.sub.14 aryl group, or a group containing a functional group in the organic portion of these groups, which is an important intermediate for preparation of pharmaceuticals and agricultural chemicals, and prepared by allowing an optically active or racemic compound represented by the general formula (1), ##STR2## (wherein A represents a C.sub.6 -C.sub.14 aryl group or a C.sub.1 -C.sub.4 alkyl or alkoxy group- or halogen-substituted C.sub.6 -C.sub.14 aryl group and R.sub.Type: GrantFiled: April 27, 1981Date of Patent: May 10, 1983Assignee: Sumitomo Chemical Company, LimitedInventors: Teruaki Mukaiyama, Yoji Sakito, Masatoshi Asami
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Patent number: 4379783Abstract: A compound of the formula ##STR1## or a pharmaceutically acceptable salt thereof, wherein: G is hydroxymethylene or carbonyl;R is hydrogen or alkanoyl having from one to seven carbon atoms;R.sub.1 and R.sub.2 are each methyl or ethyl;R.sub.3 is an alkyl of from five to seven carbon atoms;m is 0 or 1; andn is 1, 2 or 3.A preferred compound is one in which m is zero, n is one or G is hydroxymethylene. Also preferred are compounds in which R.sub.1 and R.sub.2 are methyl. Additional preferred compounds include those where R is hydrogen or acetyl. A preferred compound is Z-3-(4'-(dimethyl-n-hexylsilyl)-2'-hydroxyphenyl)cyclohexanol.The invention further comprises pharmaceutical compositions containing these compounds. In accordance with the present invention, these compounds when administered in an effective amount to mammals are useful as CNS agents including analgesics, tranquilizers, sedatives, anticonvulsants, antidiarrheals, antiemetics and antianxiety agents.Type: GrantFiled: May 24, 1982Date of Patent: April 12, 1983Assignee: Pfizer Inc.Inventors: Lawrence S. Melvin, Jr., Michael R. Johnson
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Patent number: 4375548Abstract: Silylated trichloromethyl carbinol compounds are prepared by contacting aldehydes and ketones with silylated trichloroacetates at elevated temperatures in the presence of an initiator.Type: GrantFiled: December 17, 1981Date of Patent: March 1, 1983Assignee: The Dow Chemical CompanyInventors: Pen-Chung Wang, James M. Renga
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Patent number: 4374984Abstract: Compounds of the formula ##STR1## wherein the substituents A, Z, R.sup.1, R.sup.2, R.sup.3, R.sup.4, X, n and m are defined hereinbeloware effective photoinitiators, especially for the photopolymerization of ethylenically unsaturated compounds and for the curing of printing inks.Type: GrantFiled: March 4, 1981Date of Patent: February 22, 1983Assignee: Merck Patent Gesellschaft mit Beschrankter HaftungInventors: Jurgen Eichler, Claus Herz, Karl-Heinz Neisius, Gregor Wehner
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Patent number: 4374674Abstract: There are provided ultraviolet light absorbing agents of the following general formula ##STR1## wherein: X is ##STR2## Y is H or OH, Z is H, OH, OQ or OW, where at least one Z is OH if Y is H;Q is --CH.sub.2 (CH.sub.2).sub.n Si(R.sub.2).sub.x (OR.sub.1).sub.y ; andW is --C.sub.m H.sub.2m+1 ;where x=0, 1 or 2, y=1, 2 or 3, x+y=3, R.sub.1 =alkyl or alkanoyl having 1 to 6 carbon atoms, R.sub.2 =alkyl having 1 to 6 carbon atoms, n=0, 1 or 2, and m=1 to 18. Also provided are organopolysiloxane protective coating compositions containing said ultraviolet light absorbing agents having unique utility for protecting transparent plastic articles.Type: GrantFiled: January 15, 1981Date of Patent: February 22, 1983Assignee: General Electric Co.Inventors: Bruce A. Ashby, Siegfried H. Schroeter
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Patent number: 4367340Abstract: Compounds of the general formula I are disclosed as useful intermediates in the preparation of prostanoids: ##STR1## wherein A represents O or H, OR.sub.z ;R.sup.z represents hydrogen or a protecting group;R.sup.x represents hydrogen or a protecting group; andR.sup.y represents halogen, a substituted thio group, di-substituted amino group, or a group of the formula R.sup.2, and R.sup.2 represents a straight-or branched-chain alkyl alkenyl or alkynyl group which may optionally be substituted by one or more carboxyl, carboxylic acid ester, or free or protected hydroxyl, thiol, aldehyde or keto groups;with the provisos that R.sup.x is not hydrogen when A is O and R.sup.y is R.sup.2 ; and that when A is H, OR.sup.z R.sup.y is R.sup.2 and R.sup.x and R.sup.z are not both hydrogen.Processes for the preparation of these compounds and of 2-substituted 4-hydroxy-cyclopent-2-en-1-one derivatives are also disclosed.Type: GrantFiled: March 4, 1981Date of Patent: January 4, 1983Assignee: The Australian National UniversityInventors: Rodney W. Rickards, Melvyn Gill, Robert M. Christie
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Patent number: 4360686Abstract: Active hydrogen-containing compounds are silylated by contacting with trimethylsilyl trichloroacetate at elevated temperatures in the presence of an initiator.Type: GrantFiled: September 3, 1981Date of Patent: November 23, 1982Assignee: The Dow Chemical CompanyInventors: Pen-Chung Wang, James M. Renga
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Patent number: 4359581Abstract: A process for preparing a 3-oxo-7-hydroxy-bicyclo[3,3,0]octan-2-ylcarboxylic acid ester of the formula ##STR1## wherein R.sub.1 is alkyl of 1-6 carbon atoms or phenalkyl of 7-10 carbon atoms andR.sub.2 is hydrogen, alkyl or 1-6 carbon atoms, phenalkyl of 7-10 carbon atoms, tetrahydropyranyl, tetrahydrofuranyl, .alpha.-ethoxyethyl, tri-C.sub.1-4 -alkylsilyl, wherein the alkyl moieties can optionally be substituted by phenyl, or ##STR2## wherein R.sub.3 is alkyl of 1-6 carbon atoms or aryl of 6-12 carbon atoms, comprises oxidizing the corresponding 7-hydroxy-2-oxabicyclo [3,3,0]octan-3-ylideneacetic acid ester of the formula ##STR3## wherein R.sub.1 and R.sub.2 are as defined above, to form the corresponding ketone, reacting the latter with a base which opens the ether oxygen containing ring, and then reducing the resultant product to prepare the 3-oxo-7-hydroxy-bicyclo[3,3,0]octan-2-ylcarboxylic acid ester.Type: GrantFiled: June 5, 1981Date of Patent: November 16, 1982Assignee: Schering AGInventors: Werner Skuballa, Bernd Raduechel, Helmut Vorbrueggen
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Patent number: 4352917Abstract: Silylated organic polymers which may be applied to textile materials to impart hydrophilic properties thereto are prepared by reacting polymeric organic acids with silylated aminofunctional polyethers. The resultant composition may then be crosslinked to impart durable hydrophilic properties to textile materials treated therewith.Type: GrantFiled: September 18, 1980Date of Patent: October 5, 1982Assignee: SWS Silicones CorporationInventor: Jeffrey A. Tripp
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Patent number: 4346041Abstract: The present specification provides novel analogs of carbacyclin (CBA.sub.2), 6a-carba-prostacyclin (6a-carba-PGI.sub.2), which have pronounced prostacyclin-like pharmacological activity, e.g., as platelet antiaggregatory agents. Specifically the novel chemical analogs of CBA.sub.2 are those substituted by fluoro (C-5), alkyl (C-9), interphenylene (C-5), and methano (C-6a,9). Further provided are benzindene analogs of CBA.sub.2 and substituted forms thereof, i.e., 9-deoxy-2',9-methano (or 2',9-metheno)-3-oxa-4,5,6-trinor-3,7-(1',3'-interphenylene)-PGF.sub.1 compounds. Also provided are a variety of novel chemical intermediates, e.g., substituted bicyclo[3.3.0]octane intermediates, and chemical process utilizing such intermediates which are useful in the preparation of the novel CBA.sub.2 analogs.Type: GrantFiled: December 22, 1980Date of Patent: August 24, 1982Assignee: The Upjohn CompanyInventor: Paul A. Aristoff
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Patent number: 4342742Abstract: Surface-active polysiloxanes are disclosed having the formula: ##STR1## in which x denotes an integer from 3 to 10 and A denotes a cationic, anionic, zwitterionic or nonionic hydrophilic unit which contains one or more of the same or different groups which are amine, amine oxide, ammonium, ammonioalkylcarboxylate, ammonioalkylsulphonate, amide, sulphonamide, ether, thioether, sulphoxide, hydroxyl, ester or acid groups. These polysiloxanes are particularly useful for use in cosmetic and pharmaceutical compositions, especially compositions for the hair.Type: GrantFiled: November 27, 1979Date of Patent: August 3, 1982Assignee: L'OrealInventors: Henri Sebag, Guy Vanlerberghe
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Patent number: 4339388Abstract: A synthesis of periplanone-B, a female sex pheromone of the American cockroach, P. americana, is described. Novel compounds which are useful as intermediates in the synthesis of periplanone-B are described including the precursor alcohol, periplanol-B.Type: GrantFiled: April 22, 1980Date of Patent: July 13, 1982Inventor: W. Clark Still
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Patent number: 4337348Abstract: The invention provides a benzoin group-containing cyclic organopolysiloxane, which belongs to a novel class of organosilicon compounds hitherto not known or not described in any prior art literatures. The compound has at least one benzoin group of the formula ##STR1## in which Ph is a phenyl group and R.sup.1 is a hydrogen atom or an alkyl group having from 1 to 4 carbon atoms or, in particular, a methyl group, directly bonded to the silicon atom in the cyclic tri-, tetra-, penta- or hexasiloxane. The compound is useful as a sensitizer for the crosslinking reaction of a photo- or radiation-curable organopolysiloxane composition owing to the high miscibility of the inventive compounds with the organopolysiloxane composition.Type: GrantFiled: June 17, 1981Date of Patent: June 29, 1982Assignee: Shin-Etsu Chemical Company LimitedInventors: Minoru Takamizawa, Fumio Okada, Hisashi Aoki
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Patent number: 4329483Abstract: A method for preparing cyclotetrasiloxane, aliphatic chlorides and/or acyl chlorides from a chlorosilane and an acyloxy compound is disclosed. The chlorosilane and the acyloxy compound may be present as substantially equimolar amounts of separate compounds or they may be present in the same molecule in equimolar amounts. The reactants are merely heated sufficiently, with or without a soluble halide salt catalyst, to form the products. Advantageously this method can provide cyclotetrasiloxanes having water-sensitive radicals such as silicon-bonded chlorine atoms and/or silicon-bonded acyl chloride radicals.Type: GrantFiled: July 10, 1981Date of Patent: May 11, 1982Assignee: Dow Corning CorporationInventor: John L. Speier
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Patent number: 4329482Abstract: A method for preparing cyclotetrasiloxane, aliphatic chlorides and/or acyl chlorides from a cyclotrisiloxane, a chlorosilane and an acyloxy compound is disclosed. The chlorosilane and the acyloxy compound may be present as substantially equimolar amounts of separate compounds or they may be present in the same molecule in equimolar amounts. The reactants are merely heated sufficiently, with or without a soluble halide salt catalyst, to form the products. Advantageously this method can provide cyclotetrasiloxanes having water-sensitive radicals such as silicon-bonded chlorine atoms and/or silicon-bonded acyl chloride radicals. This method also provides a method for preparing cyclotetrasiloxanes having either one type of siloxane unit (non-mixed cyclotetrasiloxanes) or more than one type of siloxane unit (mixed cyclotetrasiloxanes).Type: GrantFiled: July 10, 1981Date of Patent: May 11, 1982Assignee: Dow Corning CorporationInventor: Maher Y. A. I. Elsheikh
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Patent number: 4328352Abstract: A novel norpatchoulenol synthesis is disclosed. The key step in the synthesis is an intramolecular Diels-Alder condensation of a trisubstituted silyloxy derivative of cyclohexadienone. Novel intermediates, namely trisubstituted silyloxy methanonaphthalenes (Formula V, infra) and trisubstituted silyloxy cyclohexadienes (Formula IV, infra) are prepared.Type: GrantFiled: September 22, 1980Date of Patent: May 4, 1982Assignee: Givaudan CorporationInventor: Wolfgang Oppolzer
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Patent number: 4322357Abstract: The preparation of racemic 1R, 4R, 5R-5-(4', 8'-dimethyl-5'-hydroxy-7'-nonenyl)-5-methyl-8-oxabicyclo[3.2.1]-octane-1-a cetic acid is described. The cycloheptane compounds are active uteroevacuant agents.Type: GrantFiled: February 23, 1981Date of Patent: March 30, 1982Assignee: Ortho Pharmaceutical CorporationInventor: Ramesh M. Kanojia
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Patent number: 4322543Abstract: 4,5-Unsaturated 16-hydroxy prostanoic acid derivatives displaying valuable pharmacological properties, e.g. gastric antisecretory, are described herein.Type: GrantFiled: October 24, 1980Date of Patent: March 30, 1982Assignee: G. D. Searle & Co.Inventors: Paul W. Collins, Raphael Pappo
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Patent number: 4321184Abstract: An oxidated silicon compound will react with a substituted organic compound in the presence of an alkali compound to produce organic alkali metal silicate products which may be used as molding powders, as adhesives, as coating agents and be reacted with polyisocyanates to produce insulating foams.Type: GrantFiled: April 6, 1981Date of Patent: March 23, 1982Inventor: David H. Blount
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Patent number: 4310465Abstract: A synthesis of Vitamin E has the condensation of 2,4-pentanediene and 1,2-epoxy-2,6,10,14-tetramethylpentadecane including intermediates in this synthesis which uses base catalyzed condensations of aliphatic compounds to construct the Vitamin E molecule from aliphatic precursors.Type: GrantFiled: December 17, 1979Date of Patent: January 12, 1982Assignee: Hoffmann-La Roche Inc.Inventors: Gary L. Olson, Gabriel Saucy
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Patent number: 4308372Abstract: A shelf-stable catalyst composition for a one-part room temperature vulcanizable silicone rubber composition comprising the reaction product of an adhesion promoter selected from the class consisting of silyl maleates, silyl fumarates, silyl succinates, silyl isocyanurates and silyl cyanurates and with an acyloxy functional cross-linking agent.Type: GrantFiled: June 25, 1979Date of Patent: December 29, 1981Assignee: General Electric CompanyInventors: Alfred H. Smith, Jr., John J. Dziark
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Patent number: 4308400Abstract: Aromatic-aliphatic ketones of the formulae I, II, III or IV ##STR1## wherein n is 1 or 2, Ar is an aryl radical, R.sup.1 and R.sup.2 are monvalent aliphatic, cycloaliphatic or araliphatic radicals, R.sup.3 is a direct bond or a divalent organic radical, X is a hydroxyl or amino group or the monovalent etherification or silylation products thereof, and X' is a divalent amino, ether or silyloxy group, Y is a direct bond or CH.sub.2 and Z is O, S, SO.sub.2, CH.sub.2 or C(CH.sub.3).sub.2, are suitable sensitizers for the photopolymerization of unsaturated compounds and for the photochemical crosslinking of polyolefins. Some of these compounds are novel and can be obtained by methods analogous to those for obtaining the known compounds of this type.Type: GrantFiled: December 28, 1979Date of Patent: December 29, 1981Assignee: Ciba-Geigy A.G.Inventors: Louis Felder, Rudolf Kirchmayr, Rinaldo Husler